β-Hydroxyisovalerylshikonin regulates macrophage polarization via the AMPK/Nrf2 pathway and ameliorates sepsis in mice (Englisch)
Freier Zugriff
- Neue Suche nach: Pan, Tao
- Neue Suche nach: Chang, Yabin
- Neue Suche nach: He, Min
- Neue Suche nach: He, Zehui
- Neue Suche nach: Jiang, Jun
- Neue Suche nach: Ren, Xinling
- Neue Suche nach: Zhang, Fang
- Neue Suche nach: Pan, Tao
- Neue Suche nach: Chang, Yabin
- Neue Suche nach: He, Min
- Neue Suche nach: He, Zehui
- Neue Suche nach: Jiang, Jun
- Neue Suche nach: Ren, Xinling
- Neue Suche nach: Zhang, Fang
In:
Pharmaceutical Biology
;
60
, 1
;
729-742
;
2022
- Aufsatz (Zeitschrift) / Elektronische Ressource
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Titel:β-Hydroxyisovalerylshikonin regulates macrophage polarization via the AMPK/Nrf2 pathway and ameliorates sepsis in mice
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Beteiligte:Pan, Tao ( Autor:in ) / Chang, Yabin ( Autor:in ) / He, Min ( Autor:in ) / He, Zehui ( Autor:in ) / Jiang, Jun ( Autor:in ) / Ren, Xinling ( Autor:in ) / Zhang, Fang ( Autor:in )
-
Erschienen in:Pharmaceutical Biology ; 60, 1 ; 729-742
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Verlag:
- Neue Suche nach: Taylor & Francis
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Erscheinungsdatum:31.12.2022
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Format / Umfang:14 pages
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ISSN:
-
DOI:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Elektronische Ressource
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Sprache:Englisch
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Schlagwörter:
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Datenquelle:
Inhaltsverzeichnis – Band 60, Ausgabe 1
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Schisandra chinensis essential oil attenuates acetaminophen-induced liver injury through alleviating oxidative stress and activating autophagyZhao, Jing / Ding, Kaixin / Hou, Manting / Li, Yuanhua / Hou, Xiaorong / Dai, Wenzhang / Li, Zhiyong / Zhao, Jun / Liu, Wenlong / Bai, Zhaofang et al. | 2022
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Protective effects of lavender oil on sepsis-induced acute lung injury via regulation of the NF-κB pathwayXie, Qian / Wang, Yi / Zou, Guo-Liang et al. | 2022
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Fraxinol attenuates LPS-induced acute lung injury by equilibrating ACE-Ang II-AT1R and ACE2-Ang (1-7)-Mas and inhibiting NLRP3Wu, Yan / Yang, Xin / Ju, Yuanyuan / Zhao, Fei et al. | 2022
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Calycosin plays a protective role in diabetic kidney disease through the regulation of ferroptosisHuang, Di / Shen, Peicheng / Wang, Chen / Gao, Jiandong / Ye, Chaoyang / Wu, Feng et al. | 2022
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Study on the mechanism of lupenone for treating type 2 diabetes by integrating pharmacological evaluation and network pharmacologyXu, Feng / Zhang, Mei / Wu, Hongmei / Wang, Yuanmin / Yang, Ye / Wang, Xiangpei et al. | 2022
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Cardamonin suppressed the migration, invasion, epithelial mesenchymal transition (EMT) and lung metastasis of colorectal cancer cells by down-regulating ADRB2 expressionLu, Ting / Zheng, Chunju / Fan, Zhimin et al. | 2022
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Combination of puerarin and tanshinone IIA alleviates ischaemic stroke injury in rats via activating the Nrf2/ARE signalling pathwayMiao, Qing / Wang, Ruihai / Sun, Xiaoxin / Du, Song / Liu, Limei et al. | 2022
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Alpinetin suppresses CYP3A4, 2C9, and 2E1 activity in vitroSong, Hongming / Wei, Chuankui / Yang, Wu / Niu, Zhaohe / Gong, Mingkai / Hu, Haiyan / Wang, Haibo et al. | 2022
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Ginsenoside Rc attenuates myocardial ischaemic injury through antioxidative and anti-inflammatory effectsShi, Lei / Fu, Wenwen / Xu, Huali / Li, Shihui / Yang, Xinyu / Yang, Wei / Sui, Dayun / Wang, Quanwei et al. | 2022
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Ellagic acid attenuates beryllium sulphate-induced oxidative stress and histopathological alterations of spleen in ratsLei, Yuandi / Jiang, Tianyi / He, Liqin / Liu, Yanping / Sun, Zhanbing / Deng, Weihua / Huang, Lian / Zhang, Zhaohui et al. | 2022
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Antiperspirant effects and mechanism investigation of Mulisan decoction in rats based on plasma metabolomicsMa, Shan-Peng / Ma, Wei-Ping / Yin, Shi-Ning / Chen, Xiang-Yue / Ma, Xiao-Qing / Wei, Bao-Hong / Lu, Jing-Guang / Liu, Hong-Bing et al. | 2022
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Research progress on antiviral constituents in traditional Chinese medicines and their mechanisms of actionChen, Zhi / Ye, Si-yong et al. | 2022
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Deer antler based active ingredients have protective effects on LPS/d-GalN-induced acute liver injury in mice through MAPK and NF-κB signalling pathwaysHe, Guixiang / Zhao, Quanmin / Zhao, Yan / Zong, Ying / Gu, Shigang / Li, Mengjie / Li, Renjie / Sun, Jiaxin et al. | 2022
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Research progress on the protective effects of aucubin in neurological diseasesYang, Ping / Zhang, Qiaoyue / Shen, Hengyan / Bai, Xinyu / Liu, Ping / Zhang, Tao et al. | 2022
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Protective effect of valerian extract capsule (VEC) on ethanol- and indomethacin-induced gastric mucosa injury and ameliorative effect of VEC on gastrointestinal motility disorderFeng, Yuan / Dai, Wan / Ke, Junyu / Cui, Yong / Li, Shuang / Ma, Jingjing / Guo, Wenfeng / Chen, Gang / Li, Ning / Li, Yanwu et al. | 2022
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Myostain is involved in ginsenoside Rb1-mediated anti-obesityLi, Hong-Shi / Kuang, Jiang-Ying / Liu, Gui-Jun / Wu, Wei-Jie / Yin, Xian-Lun / Li, Hao-Dong / Wang, Lei / Qin, Tao / Zhang, Wen-Cheng / Sun, Yuan-Yuan et al. | 2022
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Prevention of ulcerative colitis by Huangqin decoction: reducing the intestinal epithelial cell apoptosis rate through the IFN-γ/JAK/ETS signalling pathwayMo, Xiaowei / Tang, Kairui / Deng, Lijing / Zhou, Xingyi / Li, Xiaojuan / Zhang, Yupei / Wang, Jing et al. | 2022
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Ethanol extract of the mushroom Coprinus comatus exhibits antidiabetic and antioxidant activities in streptozotocin-induced diabetic ratsRatnaningtyas, Nuniek Ina / Hernayanti, Hernayanti / Ekowati, Nuraeni / Husen, Fajar et al. | 2022
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Camel milk protein hydrosylate alleviates hepatic steatosis and hypertension in high fructose-fed ratsAlshuniaber, Mohammad A. / Alshammari, Ghedeir M. / Eleawa, Samy M. / Yagoub, Abu ElGasim A. / Al-Khalifah, Abdullrahman S. / Alhussain, Maha H. / Al-Harbi, Laila Naif / Yahya, Mohammed Abdo et al. | 2022
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Extract of Pinus densiflora needles suppresses acute inflammation by regulating inflammatory mediators in RAW264.7 macrophages and miceJeong, Seul-Yong / Choi, Won Seok / Kwon, Oh Seong / Lee, Jong Seok / Son, Su Young / Lee, Choong Hwan / Lee, Sarah / Song, Jin Yong / Lee, Yeon Jin / Lee, Ji-Yun et al. | 2022
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Rhodiola rosea polysaccharides promote the proliferation of bone marrow haematopoietic progenitor cells and stromal cells in mice with aplastic anaemiaLi, Jing / Chen, Yongfeng et al. | 2022
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S-Propargyl-cysteine prevents concanavalin A-induced immunological liver injury in miceMa, Beilei / Mao, Yicheng / Chang, Lingling / Dai, Tao / Xin, Xiaoming / Ma, Fenfen / Wang, Zhijun / Shen, Zhuqing / Mei, Qibing / Zhu, Yizhun et al. | 2022
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A comprehensive review of the ethnomedicine, phytochemistry, pharmacological activities of the genus KniphofiaNigussie, Gashaw / Tegegn, Metasebia / Abeje, Dessalegn / Melak, Haregua et al. | 2022
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Effects of ginkgo leaf tablet on the pharmacokinetics of rosiglitazone in rats and its potential mechanismXing, Xueting / Kong, Mengzhu / Hou, Qiaoyu / Li, Jiaqi / Qian, Wen / Chen, Xijing / Li, Hanhan / Yang, Changqing et al. | 2022
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Anti-EMT and anti-fibrosis effects of protocatechuic aldehyde in renal proximal tubular cells and the unilateral ureteral obstruction animal modelChang, Yu-Teng / Chung, Mu-Chi / Chang, Chi-Hao / Chiu, Kuan-Hsun / Shieh, Jeng-Jer / Wu, Ming-Ju et al. | 2022
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Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of actionLópez-Lorenzo, Yaraset / Sánchez-Mendoza, María Elena / Arrieta-Baez, Daniel / Perez-Ruiz, Adriana Guadalupe / Arrieta, Jesús et al. | 2022
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Investigation of cell cytotoxic activity and molecular mechanism of 5β,19-epoxycucurbita-6,23(E)-diene-3β,19(R),25-triol isolated from Momordica charantia on hepatoma cellsYuan, Mei-Kang / Kao, Ju-Wen / Wu, Wen-Tung / Chen, Chiy-Rong / Chang, Chi-I / Wu, Yu-Jen et al. | 2022
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Network pharmacology-based analysis of the mechanism of Saposhnikovia divaricata for the treatment of type I allergyLi, Xiangsheng / Li, Hui / Wang, Tingting / Zhao, Yang / Shao, Yuxin / Sun, Yizhao / Zhang, Yanfen / Liu, Zhongcheng et al. | 2022
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Comparative study on the gastrointestinal- and immune- regulation functions of Hedysari Radix Praeparata Cum Melle and Astragali Radix Praeparata cum Melle in rats with spleen-qi deficiency, based on fuzzy matter-element analysisZhang, Yugui / Niu, Jiangtao / Zhang, Shujuan / Si, Xinlei / Bian, Tian-Tian / Wu, Hongwei / Li, Donghui / Sun, Yujing / Jia, Jing / Xin, Erdan et al. | 2022
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The complex lipid, SPPCT-800, reduces lung damage, improves pulmonary function and decreases pro-inflammatory cytokines in the murine LPS-induced acute respiratory distress syndrome (ARDS) modelSordillo, Peter P. / Allaire, Andrea / Bouchard, Annie / Salvail, Dan / Labbe, Sebastien M. et al. | 2022
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Anti-liver fibrosis effects of the total flavonoids of litchi semen on CCl4-induced liver fibrosis in rats associated with the upregulation of retinol metabolismYan, Jiongyi / Feng, Yinyi / Fang, Xuewan / Cui, Xiaojuan / Xia, Xing / Li, Fang / Luo, Weisheng / Liang, Jianqin / Feng, Jianfang / Yu, Kai et al. | 2022
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Isolation, characterisation and complement fixation activity of acidic polysaccharides from Argemone mexicana used as antimalarials in MaliDénou, Adama / Togola, Adiaratou / Inngjerdingen, Kari Tvete / Moussavi, Nastaran / Rise, Frode / Zou, Yuan Feng / Dafam, Dalen G. / Nep, Elijah I. / Ahmed, Abubakar / Alemika, Taiwo E. et al. | 2022
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Repair mechanism of Wuwei Fuzheng Yijing formula in di-2-ethylhexyl phthalate-induced sperm DNA fragmentation in miceZhang, Chenming / Wang, Shiqi / Wang, Zulong / Zhang, Qi / Chen, Rubing / Zhang, Hao / Hua, Zhong / Ma, Sicheng et al. | 2022
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Morinda officinalis polysaccharide enable suppression of osteoclastic differentiation by exosomes derived from rat mesenchymal stem cellsWu, Peiyu / Jiao, Feng / Huang, He / Liu, Donghua / Tang, Wang / Liang, Jie / Chen, Wen et al. | 2022
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Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamilChowański, Szymon / Winkiel, Magdalena / Szymczak-Cendlak, Monika / Marciniak, Paweł / Mańczak, Dominika / Walkowiak-Nowicka, Karolina / Spochacz, Marta / Bufo, Sabino A. / Scrano, Laura / Adamski, Zbigniew et al. | 2022
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Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacologyTian, Jie / Wang, Xiao-Long / Wang, Long-Cheng / Chen, Fei / Tian, Yun / Ma, Li / Pan, Chao-Yun / Wang, Yan-Ping et al. | 2022
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Sleep-promoting activity of lotus (Nelumbo nucifera) rhizome water extract via GABAA receptorsAhn, Yejin / Kim, Singeun / Park, Chunwoong / Kim, Jung Eun / Suh, Hyung Joo / Jo, Kyungae et al. | 2022
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An integrated strategy for the comprehensive profiling of the chemical constituents of Aspongopus chinensis using UPLC-QTOF-MS combined with molecular networkingZhang, Fengyu / Li, Bichen / Wen, Ying / Liu, Yanyang / Liu, Rong / Liu, Jing / Liu, Shao / Jiang, Yueping et al. | 2022
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Improvement of irradiation-induced fibroblast damage by α2-macroglobulin through alleviating mitochondrial dysfunctionHuangfu, Chaoji / Tang, Nan / Yang, Xiaokun / Gong, Zhanwei / Li, Junzheng / Jia, Junting / Zhang, Jingang / Huang, Yan / Ma, Yuyuan et al. | 2022
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Cytotoxic effects of extracts obtained from plants of the Oleaceae family: bio-guided isolation and molecular docking of new secoiridoids from Jasminum humileMansour, Khaled Ahmed / Elbermawi, Ahmed / Al-Karmalawy, Ahmed A. / Lahloub, Mohamed-Farid / El-Neketi, Mona et al. | 2022
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Evaluation of the toxicology, anti-lipase, and antioxidant effects of Callistemon citrinus in rats fed with a high fat-fructose dietOrtega-Pérez, Luis Gerardo / Piñón-Simental, Jonathan Saúl / Magaña-Rodríguez, Oliver Rafid / Lopéz-Mejía, Alejandro / Ayala-Ruiz, Luis Alberto / García-Calderón, Aram Josué / Godínez-Hernández, Daniel / Rios-Chavez, Patricia et al. | 2022
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Network pharmacology approach to investigate the multitarget mechanisms of Zhishi Rhubarb Soup on acute cerebral infarctionShao, Yuejia / Zhang, Yue / Wu, Rongrong / Dou, Lurui / Cao, Fengjiao / Yan, Yuqing / Tang, Yuming / Huang, Chi / Zhao, Yang / Zhang, Jinghua et al. | 2022
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Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathwayWang, Hui / Jiang, Qingtao / Zhang, Lizhu et al. | 2022
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Integrated serum pharmacochemistry and investigation of the anti-gastric ulcer effect of Zuojin pill in rats induced by ethanolZhang, Jiaying / Yin, Yi / Xu, Qianqian / Che, Xiaoqing / Yu, Chen / Ren, Yan / Li, Dongsheng / Zhao, Juanjuan et al. | 2022
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Antidepressant effects of total alkaloids of Fibraurea recisa on improving corticosterone-induced apoptosis of HT-22 cells and chronic unpredictable mild stress-induced depressive-like behaviour in miceHe, Zhongmei / Yu, He / Wu, Hong / Su, Lili / Shi, Kun / Zhao, Yan / Zong, Ying / Chen, Weijia / Du, Rui et al. | 2022
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A novobiocin derivative, XN4, triggers ferroptosis in gastric cancer cells via the activation of NOX4Li, Rongrong / Yin, Bin / Zeng, Deyu / Liu, Zhenyang et al. | 2022
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Salvianolic acid B inhibits myocardial I/R-induced ROS generation and cell apoptosis by regulating the TRIM8/GPX1 pathwayLu, Bo / Li, Jianhua / Gui, MingTai / Yao, Lei / Fan, Mingsong / Zhou, Xunjie / Fu, Deyu et al. | 2022
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Combination of paeoniflorin and calycosin-7-glucoside alleviates ischaemic stroke injury via the PI3K/AKT signalling pathwayWang, Peng-Cheng / Wang, Sheng-Xin / Yan, Xiang-Li / He, Ying-Ying / Wang, Min-Chun / Zheng, Hao-Zhen / Shi, Xu-Guang / Tan, Yong-Heng / Wang, Li-Sheng et al. | 2022
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Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing lossYang, Yi-Fang / Yan, Xi-Rui / Wu, Rui-Xin / Li, Ning / Chu, Min / Dong, Yang / Fu, Shu-Ping / Shi, Jian-Rong / Liu, Qing et al. | 2022
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Antiproliferative activity, cell-cycle arrest, apoptotic induction and LC-HRMS/MS analyses of extracts from two Linum speciesMouna, Ryma / Broisat, Alexis / Ahmed, Abdalwahab / Debiossat, Marlène / Boumendjel, Ahcène / Ghezzi, Catherine / Kabouche, Zahia et al. | 2022
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Aaptamine – a dual acetyl – and butyrylcholinesterase inhibitor as potential anti-Alzheimer’s disease agentMiao, Shuang / He, Qianqian / Li, Chen / Wu, Yan / Liu, Mengshan / Chen, Yongshou / Qi, Shizhou / Gong, Kaikai et al. | 2022
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Antiproliferative and cytotoxic effects of sesquiterpene lactones isolated from Ambrosia artemisiifolia on human adenocarcinoma and normal cell linesKovács, Balázs / Szemerédi, Nikoletta / Kúsz, Norbert / Kiss, Tivadar / Csupor-Löffler, Boglárka / Tsai, Yu-Chi / Rácz, Bálint / Spengler, Gabriella / Csupor, Dezső et al. | 2022
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Louki Zupa decoction attenuates the airway inflammation in acute asthma mice induced by ovalbumin through IL-33/ST2-NF-κB/GSK3β/mTOR signalling pathwayHuang, Xi / Yu, Hang / Xie, Cong / Zhou, Yao-Long / Chen, Meng-Meng / Shi, Han-Lin / Tang, Wei-Feng / Dong, Jing-Cheng / Luo, Qing-Li et al. | 2022
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Effect of Wuzi Yanzong prescription on oligoasthenozoospermia rats based on UPLC-Q-TOF-MS metabolomicsChen, Zhimin / Dong, Baohua / Jiang, Yunxiu / Peng, Ying / Li, Wenbing / Yu, Lingying / Gao, Yongxiang / Hu, Changjiang et al. | 2022
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Jiedutongluotiaogan formula restores pancreatic function by suppressing excessive autophagy and endoplasmic reticulum stressLuo, Jinli / Jin, Wenqi / Jin, Meiying / Pan, Weiwei / Gao, Shengnan / Zhao, Xiaohua / Lai, Xingrong / Sun, Liwei / Piao, Chunli et al. | 2022
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Paclitaxel induces cognitive impairment via necroptosis, decreased synaptic plasticity and M1 polarisation of microgliaTang, Miao / Zhao, Shuang / Liu, Jia-Xin / Liu, Xin / Guo, Yue-Xian / Wang, Gui-Ying / Wang, Xiu-Li et al. | 2022
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Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitroYang, Yang / Ren, Zhen-Zhen / Wei, Wu-Jun / He, Zhi-Long / Deng, You-Lin / Wang, Zhuan / Fan, Yu-Chun / Zhou, Jie / Jiang, Li-He et al. | 2022
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Assessing potential liver injury induced by Polygonum multiflorum using potential biomarkers via targeted sphingolipidomicsJia, Zhixin / Liu, Lirong / Liu, Jie / Fang, Cong / Pan, Mingxia / Zhang, Jingxuan / Li, Yueting / Xian, Zhong / Xiao, Hongbin et al. | 2022
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In vitro differences in toddalolactone metabolism in various species and its effect on cytochrome P450 expressionShan, Lina / Shi, Xianbao / Hu, Tingting / Hu, Jiayin / Guo, Zhe / Song, Yonggui / Su, Dan / Zhang, Xiaoyong et al. | 2022
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Danggui Niantong granules ameliorate rheumatoid arthritis by regulating intestinal flora and promoting mitochondrial apoptosisLu, Qi-Jin / Li, Jia-Yu / Lin, Hong-Xin / Cai, Yi-Si / Liu, Chang-Shun / Fu, Li-Ping / Liu, Gang / Yuan, Li-Xia et al. | 2022
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Aidi injection reduces doxorubicin-induced cardiotoxicity by inhibiting carbonyl reductase 1 expressionLu, Yuan / Liu, Wen / Lv, Ting / Wang, Yanli / Liu, Ting / Chen, Yi / Jin, Yang / Huang, Jin / Zheng, Lin / Huang, Yong et al. | 2022
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Effects of osthole on osteoporotic rats: a systematic review and meta-analysisWu, Bin / Zhu, Xiu-Fang / Yang, Xiao-Qiang / Wang, Wei-Yi / Lu, Jian-Hua et al. | 2022
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Asiaticoside reverses M2 phenotype macrophage polarization-evoked osteosarcoma cell malignant behaviour by TRAF6/NF-κB inhibitionLi, Dang-ke / Wang, Guang-hui et al. | 2022
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Chlorogenic acid promotes angiogenesis and attenuates apoptosis following cerebral ischaemia-reperfusion injury by regulating the PI3K-Akt signallingFan, Yong / Li, Yongkun / Yang, Yongkai / Lin, Kunzhe / Lin, Qingqiang / Luo, Shenghui / Zhou, Xiaohui / Lin, Qun / Zhang, Fan et al. | 2022
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New insights on the phytochemical intervention for the treatment of neuropsychiatric disorders using the leaves of Michelia champaca: an in vivo and in silico approachV. H., Pushpa / M. K., Jayanthi / H. R., Rashmi / Shivamurthy, Veeresh Kumar N. / Patil, Shashank M. / Shirahatti, Prithvi S. / Ramu, Ramith et al. | 2022
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Correction| 2022
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Effects of Bushen Yiyuan recipe on testosterone synthesis in Leydig cells of rats with exercise-induced low serum testosterone levelsWang, Yirong / Peng, Xiyang / Zhou, Zhihong / Tang, Changfa / Liu, Wenfeng et al. | 2022
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Kuhuang injection exerts a protective effect by activating PPAR-γ in an in vitro model of chlorpromazine-induced cholestatic liver injury constructed by tissue engineeringWu, Qiao / Duan, Zhongping / Huang, Long / Li, Zhijie et al. | 2022
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Kirenol alleviates diabetic nephropathy via regulating TGF-β/Smads and the NF-κB signal pathwayLi, Jialin / Zhang, Jiawen / Yang, Meng / Huang, Xiaocui / Zhang, Meng / Fang, Xiansong / Wu, Suzhen et al. | 2022
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The changes of hepatic bile acid synthesis and transport and bile acids profiles in isopsoralen-induced liver injury C57BL/6J miceMen, Wei-jie / Meng, Zhao-jun / Wang, Qin / Chen, Meng-ying / Zhai, Yu-xia / Shi, Hong / Wang, An-hong / Zhou, Kun et al. | 2022
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Astragalus polysaccharide (APS) attenuated PD-L1-mediated immunosuppression via the miR-133a-3p/MSN axis in HCCHe, Lihua / Xu, Kecheng / Niu, Lizhi / Lin, Lizhu et al. | 2022
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Modified Taohong Siwu decoction improves cardiac function after myocardial ischaemia and reperfusion in rats by promoting endogenous stem cell mobilization and regulating metabolitesMeng, Wan-ting / Xiao, Zhong-Xin / Li, Han / Wang, Ya-chao / Zhao, Yue / Zhu, Yan / Guo, Hai-dong et al. | 2022
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Protective effect of salidroside on streptozotocin-induced diabetic nephropathy by inhibiting oxidative stress and inflammation in rats via the Akt/GSK-3β signalling pathwayPei, Delong / Tian, Shengri / Bao, Yanqiu / Zhang, Jun / Xu, Dongyuan / Piao, Minhu et al. | 2022
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Tao-Hong-Si-Wu decoction improves depressive symptoms in model rats via amelioration of BDNF-CREB-arginase I axis disordersZhang, Xiaoping / Li, Zeng / Shen, Chuanpu / He, Jinzhi / Wang, Longfei / Di, Lei / Rui, Bin / Li, Ning / Liu, Zhicheng et al. | 2022
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Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validationQu, Yan-Jie / Ding, Min-Rui / Gu, Chao / Zhang, Li-Min / Zhen, Rong-Rong / Chen, Jin-Fang / Hu, Bing / An, Hong-Mei et al. | 2022
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Small ubiquitin-related modifier (SUMO)ylation of SIRT1 mediates (-)-epicatechin inhibited- differentiation of cardiac fibroblasts into myofibroblastsLuo, Yingchun / Lu, Jing / Wang, Zeng / Wang, Lu / Wu, Guodong / Guo, Yuanyuan / Dong, Zengxiang et al. | 2022
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Antioxidant properties of polyphenols from snow chrysanthemum (Coreopsis tinctoria) and the modulation on intestinal microflora in vitroZhang, Minghao / Zhao, Naiyu / Xie, Minhao / Dong, Deqiao / Chen, Weilin / He, Yuanpeng / Yan, Dalin / Fu, Haiyan / Liang, Xinlin / Zhou, Li et al. | 2022
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Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathwayJiao, Yuhan / Xin, Ming / Xu, Juanjuan / Xiang, Xindong / Li, Xuan / Jiang, Jingjing / Jia, Xiuqin et al. | 2022
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Jing-an oral liquid alleviates Tourette syndrome via the NMDAR/MAPK/CREB pathway in vivo and in vitroXi, Leying / Ji, Xixi / Ji, Wenxiu / Yang, Yue’e / Zhang, Yajie / Long, Hongyan et al. | 2022
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Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathwayBian, Yaoyao / Xue, Mei / Guo, Xinlong / Jiang, Wenjuan / Zhao, Ye / Zhang, Zhaofeng / Wang, Xian / Hu, Yongkang / Zhang, Qi / Dun, Wenliang et al. | 2022
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The BCL2/BAX/ROS pathway is involved in the inhibitory effect of astragaloside IV on pyroptosis in human umbilical vein endothelial cellsSu, Yi / Yin, Xin / Huang, Xin / Guo, Qianqian / Ma, Mingyuan / Guo, Liheng et al. | 2022
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Integrated strategy of RNA-sequencing and network pharmacology for exploring the protective mechanism of Shen-Shi-Jiang-Zhuo formula in rat with non-alcoholic fatty liver diseaseXu, Zheng / Wu, Fan-Wei / Niu, Xuan / Lu, Xiao-Peng / Li, Yan-Rong / Zhang, Shu-Ting / Ou, Jun-Zhao / Wang, Xue-Mei et al. | 2022
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Bullatine A exerts anti-inflammatory effects by inhibiting the ROS/JNK/NF-κB pathway and attenuating systemic inflammatory responses in miceLiu, Shuhan / Che, Na / Ou, Wen / Yan, Meichen / Liao, Yajin / Cheng, Yong et al. | 2022
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Mechanism of lily bulb and Rehmannia decoction in the treatment of lipopolysaccharide-induced depression-like rats based on metabolomics study and network pharmacologyChi, Xiansu / Xue, Xiaoyan / Pan, Jin / Wu, Jiang / Shi, Huishan / Wang, Yong / Lu, Yanting / Zhang, Zhe / Ma, Ke et al. | 2022
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Sasanquasaponin inhibited epithelial to mesenchymal transition in prostate cancer by regulating the PI3K/Akt/mTOR and Smad pathwaysLi, Wenfeng / Mao, Yuanshen / Hua, Bao / Gu, Xin / Lu, Chao / Xu, Bin / Pan, Weixin et al. | 2022
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Genistein-induced mitochondrial dysfunction and FOXO3a/PUMA expression in non-small lung cancer cellsChan, Liujia / Pang, Yuheng / Wang, Yuji / Zhu, Di / Taledaohan, Ayijinag / Jia, Yijiang / Zhao, Lichun / Wang, Wenjing et al. | 2022
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Guanxin V attenuates myocardial ischaemia reperfusion injury through regulating iron homeostasisZhou, Fuqiong / Zhang, Zhengguang / Wang, Meiyuan / Zhu, Weina / Ruan, Jie / Long, Hongyan / Zhang, Yajie / Gu, Ning et al. | 2022
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Thais savignyi tissue extract: bioactivity, chemical composition, and molecular dockingHabib, Mohamed R. / Hamed, Ahmed A. / Ali, Rasha E. M. / Zayed, Khaled M. / Gad El-Karim, Rasha M. / Sabour, Rehab / Abu El-Einin, Hanaa M. / Ghareeb, Mosad A. et al. | 2022
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Echinatin mitigates sevoflurane-induced hippocampal neurotoxicity and cognitive deficits through mitigation of iron overload and oxidative stressXu, Zilong / You, Yanqiu / Tang, Qiuqin / Zeng, Hui / Zhao, Tianshou / Wang, Juan / Li, Fujun et al. | 2022
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Ethnomedicinal plants used for treatment of snakebites in Tanzania – a systematic reviewMogha, Neema Gideon / Kalokora, Olivia John / Amir, Halima Mvungi / Kacholi, David Sylvester et al. | 2022
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Dolichandrone serrulata flower improves seminal biochemical parameters and proteins in T2DM rats induced by a high-fat diet and streptozotocinSawatpanich, Tarinee / Chaimontri, Chadaporn / Wu, Alexander Tsang-Hsien / Iamsaard, Sitthichai / Yannasithinon, Supataechasit et al. | 2022
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Pharmacokinetic study on the co-administration of abemaciclib and astragaloside IV in ratsSun, Sen / Liu, Lu / Song, Hongming / Li, Hong et al. | 2022
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Gypenosides counteract hepatic steatosis and intestinal barrier injury in rats with metabolic associated fatty liver disease by modulating the adenosine monophosphate activated protein kinase and Toll-like receptor 4/nuclear factor kappa B pathwaysShen, Shuhua / Wang, Kungen / Zhi, Yihui / Dong, Yue et al. | 2022
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Upregulation of claudin‑4 by Chinese traditional medicine Shenfu attenuates lung tissue damage by acute lung injury aggravated by acute gastrointestinal injuryZheng, Yueliang / Zheng, Mian / Shao, Jing / Jiang, Chengxing / Shen, Jian / Tao, Rujia / Deng, Yuqin / Xu, Yingge / Lu, Yuanqiang et al. | 2022
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Volatile composition, antidiabetic, and anti-obesity potential of Brassica incana leaf and flowering top extractsTaviano, Maria Fernanda / Núñez, Sonia / Millán-Laleona, Adrián / Condurso, Concetta / Verzera, Antonella / Merlino, Maria / Ragusa, Monica / Miceli, Natalizia / López, Víctor et al. | 2022
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TangNaiKang, herbal formulation, alleviates obesity in diabetic SHR/cp rats through modulation of gut microbiota and related metabolic functionsTian, Peng / Wu, Lili / Kudo, Maya / Hayashi, Misa / Qin, Lingling / Gao, Ming / Xu, Anlong / Liu, Tonghua et al. | 2022
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Shenlian extract attenuates myocardial ischaemia-reperfusion injury via inhibiting M1 macrophage polarization by silencing miR-155Song, Min / Cui, Xihe / Zhang, Jing / Li, Yujie / Li, Jingjing / Zang, Yuanlong / Li, Qi / Yang, Qing / Chen, Ying / Cai, Weiyan et al. | 2022
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Bazi Bushen capsule attenuates cognitive deficits by inhibiting microglia activation and cellular senescenceJi, Chuanyuan / Wei, Cong / Li, Mengnan / Shen, Shuang / Zhang, Shixiong / Hou, Yunlong / Wu, Yiling et al. | 2022
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Anti-inflammatory effect of Gyeji-tang in a chronic obstructive pulmonary disease mouse model induced by cigarette smoke and lipopolysaccharideBaek, Eun Bok / Kim, Yu Jin / Rho, Jin-Hyung / Hong, Eun-Ju / Lee, Mee-Young / Kwun, Hyo-Jung et al. | 2022
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Natural products from medicinal plants in Asia and the Pacific for RNA viruses: Hercules’ fifth labourSulaiman, Mazdida / Zarubaev, Vladimir / Samudi, Chandramathi / Rahmatullah, Mohammed / Jannat, Khoshnur / Paul, Alok / Rajagopal, Mogana / Selvaraja, Malarvili / Nissapatorn, Veeranoot / Suleiman, Monica et al. | 2022
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The anti-inflammatory activity of resveratrol in acute kidney injury: a systematic review and meta‐analysis of animal studiesCao, Shangmei / Fu, Xiuhong / Yang, Shaozhe / Tang, Shuifu et al. | 2022
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A clinical herbal prescription Gu-Shu-Kang capsule exerted beneficial effects on the musculoskeletal system of dexamethasone-treated mice by acting on tissue IGF-1 signalling pathwayLi, Xiao-Li / Wang, Liang / He, Ming-Chao / Li, Wen-Xiong / Zhang, Jia-Li / Fu, Yong-Fang / Zhang, Yan et al. | 2022
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The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathwayZhang, Yan / Liu, Qinghuan / Zhang, Ting / Wang, Hong / Fu, Yu / Wang, Wentong / Li, Dongdong et al. | 2022
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Qushi Huayu decoction attenuated hepatic lipid accumulation via JAK2/STAT3/CPT-1A-related fatty acid β-oxidation in mice with non-alcoholic steatohepatitisSun, QinMei / Wang, Xin / Xin, Xin / An, ZiMing / Hu, YiYang / Feng, Qin et al. | 2022
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Ameliorative effect of chitosan nanoparticles against carbon tetrachloride-induced nephrotoxicity in Wistar ratsNomier, Yousra A. / Alshahrani, Saeed / Elsabahy, Mahmoud / Asaad, Gihan F. / Hassan, Azza / El-Dakroury, Walaa A. et al. | 2022
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Veratramine ameliorates pain symptoms in rats with diabetic peripheral neuropathy by inhibiting activation of the SIGMAR1-NMDAR pathwayZhang, Yu / Ye, Guangyao / Chen, Yuebo / Sheng, Chaoxu / Wang, Jianlin / Kong, Lingsi / Yuan, Liyong / Lin, Chunyan et al. | 2022
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Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulationEi, Zin Zin / Hutamekalin, Pilaiwanwadee / Prommeenate, Peerada / Singh, Avtar / Benjakul, Soottawat / Visuttijai, Kittichate / Chanvorachote, Pithi et al. | 2022
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Therapeutic potential of plant iridoids in depression: a reviewKou, Yaoyao / Li, Zhihao / Yang, Tong / Shen, Xue / Wang, Xin / Li, Haopeng / Zhou, Kun / Li, Luyao / Xia, Zhaodi / Zheng, Xiaohui et al. | 2022
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Herbal remedies used by traditional healers to treat haemorrhoids in Tabora region, TanzaniaKacholi, David Sylvester / Mvungi Amir, Halima et al. | 2022
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Mechanism of Huangqi–Honghua combination regulating the gut microbiota to affect bile acid metabolism towards preventing cerebral ischaemia–reperfusion injury in ratsWang, Kai / Chen, Yue / Cao, Jinyi / Liang, Ruimin / Qiao, Yi / Ding, Likun / Yang, Xiaojuan / Yang, Zhifu et al. | 2022
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Ganoderma lucidum polysaccharides ameliorate lipopolysaccharide-induced acute pneumonia via inhibiting NRP1-mediated inflammationZhang, Xuelian / Wu, Daoshun / Tian, Yu / Chen, Xiangdong / Lan, Jin / Wei, Fei / Li, Ye / Luo, Yun / Sun, Xiaobo et al. | 2022
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Catalpol relieved angiotensin II-induced blood–brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cellsXia, Yu / Lu, Yun Wei / Hao, Ren Juan / Yu, Gu Ran et al. | 2022
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Isoorientin ameliorates osteoporosis and oxidative stress in postmenopausal ratsCao, Zhilin / Liu, Wei / Bi, Benjun / Wu, Hao / Cheng, Gong / Zhao, Zhongyuan et al. | 2022
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Ginsenoside Rb1 reduces oxidative/carbonyl stress damage and ameliorates inflammation in the lung of streptozotocin-induced diabetic ratsSu, Hao / Tian, Cheng-Ju / Wang, Ying / Shi, Jiaojiao / Chen, Xiaoxiao / Zhen, Zhong / Bai, Yu / Deng, Lan / Feng, Chunpeng / Ma, Zhuang et al. | 2022
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Deciphering the anti-filarial potential of bioactive compounds from Ocimum sanctum: a combined experimental and computational studyMishra, Ayushi / Kumar, Vipin / Singh, Anchal et al. | 2022
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Rongjin Niantong Fang ameliorates cartilage degeneration by regulating the SDF-1/CXCR4-p38MAPK signalling pathwayChen, Jun / Chen, Nan / Zhang, Ting / Lin, Jie / Huang, Yunmei / Wu, Guangwen et al. | 2022
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Factors determining the oral absorption and systemic disposition of zeaxanthin in rats: in vitro, in situ, and in vivo evaluationsSeo, Seong‑Wook / Han, Dong‑Gyun / Choi, Eugene / Seo, Min‑Jeong / Song, Im‑Sook / Yoon, In‑Soo et al. | 2022
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13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathwayHsu, Chang-Min / Lin, Jen-Jie / Su, Jui-Hsin / Liu, Chih-I et al. | 2022
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Ferulic acid alleviates alveolar epithelial barrier dysfunction in sepsis-induced acute lung injury by activating the Nrf2/HO-1 pathway and inhibiting ferroptosisTang, Xianming / Liu, Jiqiang / Yao, Shuo / Zheng, Jianfei / Gong, Xun / Xiao, Bing et al. | 2022
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Curcuma longa and Boswellia serrata extract combination for hand osteoarthritis: an open-label pre-post trialHenrotin, Yves / Dierckxsens, Yvan / Delisse, Gaëlle / Maes, Nathalie / Albert, Adelin et al. | 2022
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Solid lipid nanoparticle as an effective drug delivery system of a novel curcumin derivative: formulation, release in vitro and pharmacokinetics in vivoZhao, Wenmei / Zeng, Mingtang / Li, Ke / Pi, Chao / Liu, Zerong / Zhan, Chenglin / Yuan, Jiyuan / Su, Zhilian / Wei, Yuxun / Wen, Jie et al. | 2022
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Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) ratsHe, Zhen / Zhang, Mengjuan / Xu, Hepeng / Zhou, Wenping / Xu, Chang / Wang, Zheng / He, Ming / Wang, Xiangting et al. | 2022
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Didymin, a natural flavonoid, relieves the progression of myocardial infarction via inhibiting the NLR family pyrin domain containing 3 inflammasomeZhang, Yong / RuXian, GuLi et al. | 2022
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Resveratrol accelerates wound healing by inducing M2 macrophage polarisation in diabetic miceDing, Youjun / Yang, Ping / Li, Shiyan / Zhang, Hao / Ding, Xiaofeng / Tan, Qian et al. | 2022
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Integration of network pharmacology and intestinal flora to investigate the mechanism of action of Chinese herbal Cichorium intybus formula in attenuating adenine and ethambutol hydrochloride-induced hyperuricemic nephropathy in ratsLi, Na / Amatjan, Mukaram / He, Pengke / Zhang, Boheng / Mai, Xianyan / Jiang, Qianle / Xie, Haochen / Shao, Xiaoni et al. | 2022
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XiaoEr LianHuaQinqGan alleviates viral pneumonia in mice infected by influenza A and respiratory syncytial virusesLi, Wenyan / Li, Tongtong / Zhao, Chi / Song, Tao / Mi, Yao / Chuangfeng, Zhang / Hou, Yunlong / Jia, Zhenhua et al. | 2022
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A tribute to Prof. em. Dr. Dr. h.c. mult. Hildebert WagnerBauer, Rudolf et al. | 2022