A comprehensive review on tyrosinase inhibitors (Englisch)
Freier Zugriff
- Neue Suche nach: Zolghadri, Samaneh
- Neue Suche nach: Bahrami, Asieh
- Neue Suche nach: Hassan Khan, Mahmud Tareq
- Neue Suche nach: Munoz-Munoz, J.
- Neue Suche nach: Garcia-Molina, F.
- Neue Suche nach: Garcia-Canovas, F.
- Neue Suche nach: Saboury, Ali Akbar
- Neue Suche nach: Zolghadri, Samaneh
- Neue Suche nach: Bahrami, Asieh
- Neue Suche nach: Hassan Khan, Mahmud Tareq
- Neue Suche nach: Munoz-Munoz, J.
- Neue Suche nach: Garcia-Molina, F.
- Neue Suche nach: Garcia-Canovas, F.
- Neue Suche nach: Saboury, Ali Akbar
In:
Journal of Enzyme Inhibition and Medicinal Chemistry
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34
, 1
;
279-309
;
2019
- Aufsatz (Zeitschrift) / Elektronische Ressource
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Titel:A comprehensive review on tyrosinase inhibitors
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Beteiligte:Zolghadri, Samaneh ( Autor:in ) / Bahrami, Asieh ( Autor:in ) / Hassan Khan, Mahmud Tareq ( Autor:in ) / Munoz-Munoz, J. ( Autor:in ) / Garcia-Molina, F. ( Autor:in ) / Garcia-Canovas, F. ( Autor:in ) / Saboury, Ali Akbar ( Autor:in )
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Erschienen in:Journal of Enzyme Inhibition and Medicinal Chemistry ; 34, 1 ; 279-309
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Verlag:
- Neue Suche nach: Taylor & Francis
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Erscheinungsdatum:01.01.2019
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Format / Umfang:31 pages
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ISSN:
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DOI:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Elektronische Ressource
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Sprache:Englisch
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Schlagwörter:
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Datenquelle:
Inhaltsverzeichnis – Band 34, Ausgabe 1
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Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
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Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5Hwang, Soyoung / Kang, Jung Yun / Kim, Min Jae / Shin, Dong Min / Hong, Jeong Hee et al. | 2019
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Discovery of cyanopyridine scaffold as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors through virtual screening and preliminary hit optimisationXu, Xi / Ren, Jie / Ma, Yinghe / Liu, Hongting / Rong, Quanjin / Feng, Yifan / Wang, Yameng / Cheng, Yu / Ge, Ruijia / Li, Zhiyu et al. | 2019
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A comprehensive review on tyrosinase inhibitorsZolghadri, Samaneh / Bahrami, Asieh / Hassan Khan, Mahmud Tareq / Munoz-Munoz, J. / Garcia-Molina, F. / Garcia-Canovas, F. / Saboury, Ali Akbar et al. | 2019
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Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2Chiu, Yi-Lin / Wu, Yi-Ying / Barndt, Robert B. / Yeo, Yee Hui / Lin, Yu-Wen / Sytwo, Hou-Ping / Liu, Huan-Cheng / Xu, Yuan / Jia, Bailing / Wang, Jehng-Kang et al. | 2019
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Evaluation of the anticancer potential of a sulphonamide carbonic anhydrase IX inhibitor on cervical cancer cellsKoyuncu, Ismail / Tülüce, Yasin / Slahaddin Qadir, Hewa / Durgun, Mustafa / Supuran, Claudiu T. et al. | 2019
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Inhibition potential of phenolic constituents from the aerial parts of Tetrastigma hemsleyanum against soluble epoxide hydrolase and nitric oxide synthaseWang, Cai Yi / Lee, Sunggun / Jang, Hyun-Jae / Su, Xiang Dong / Wang, Heng-Shan / Kim, Young Ho / Yang, Seo Young et al. | 2019
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The protective role of jervine against radiation-induced gastrointestinal toxicityYakan, Selvinaz / Aydin, Tuba / Gulmez, Canan / Ozden, Ozkan / Eren Erdogan, Kivilcim / Daglioglu, Yusuf Kenan / Andic, Fundagul / Atakisi, Onur / Cakir, Ahmet et al. | 2019
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CRISPR/Cas9-based liver-derived reporter cells for screening of mPGES-1 inhibitorsChen, Zhanfei / Cai, Xiaoling / Li, Man / Yan, LinLin / Wu, Luxi / Wang, Xiaoqian / Tang, Nanhong et al. | 2019
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Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hoppingZhang, Zhimin / Gu, Lili / Wang, Beibei / Huang, Wenhai / Zhang, Yanmin / Ma, Zhen / Zeng, Shenxin / Shen, Zhengrong et al. | 2019
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The antitumor activity of CYB-L10, a human topoisomerase IB catalytic inhibitorYu, Qian / Chen, Yu / Yang, Hui / Zhang, Hong-Li / Agama, Keli / Pommier, Yves / An, Lin-Kun et al. | 2019
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New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agentsChiarelli, Laurent R. / Mori, Matteo / Beretta, Giangiacomo / Gelain, Arianna / Pini, Elena / Sammartino, Josè Camilla / Stelitano, Giovanni / Barlocco, Daniela / Costantino, Luca / Lapillo, Margherita et al. | 2019
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Design, synthesis, and apoptosis-promoting effect evaluation of novel pyrazole with benzo[d]thiazole derivatives containing aminoguanidine unitsLiu, Da Chuan / Gao, Mei Jia / Huo, Qiang / Ma, Tao / Wang, Ying / Wu, Cheng Zhu et al. | 2019
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Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profileMghwary, Aml E.-S. / Gedawy, Ehab M. / Kamal, Aliaa M. / Abuel-Maaty, Suzan M. et al. | 2019
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Sesquiterpenoids and 2-(2-phenylethyl)chromones respectively acting as α-glucosidase and tyrosinase inhibitors from agarwood of an Aquilaria plantYang, Li / Yang, Yi-Ling / Dong, Wen-Hua / Li, Wei / Wang, Pei / Cao, Xue / Yuan, Jing-Zhe / Chen, Hui-Qin / Mei, Wen-Li / Dai, Hao-Fu et al. | 2019
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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogsShalaby, Raed / Petzer, Jacobus P. / Petzer, Anél / Ashraf, Usman M. / Atari, Ealla / Alasmari, Fawaz / Kumarasamy, Sivarajan / Sari, Youssef / Khalil, Ashraf et al. | 2019
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In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimersJanockova, Jana / Korabecny, Jan / Plsikova, Jana / Babkova, Katerina / Konkolova, Eva / Kucerova, Dana / Vargova, Jana / Koval, Jan / Jendzelovsky, Rastislav / Fedorocko, Peter et al. | 2019
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Antioxidant activity and antibacterial evaluation of new thiazolin-4-one derivatives as potential tryptophanyl-tRNA synthetase inhibitorsStana, Anca / Vodnar, Dan C. / Marc, Gabriel / Benedec, Daniela / Tiperciuc, Brînduşa / Tamaian, Radu / Oniga, Ovidiu et al. | 2019
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Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanomaQin, Feifei / Wang, Yali / Jiang, Xian / Wang, Yujia / Zhang, Nan / Wen, Xiang / Wang, Lian / Jiang, Qinglin / He, Gu et al. | 2019
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Evaluation of caffeine as inhibitor against collagenase, elastase and tyrosinase using in silico and in vitro approachEun Lee, Kyung / Bharadwaj, Shiv / Yadava, Umesh / Gu Kang, Sang et al. | 2019
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Benzonate derivatives of acetophenone as potent α-glucosidase inhibitors: synthesis, structure–activity relationship and mechanismDan, Wen-Jia / Zhang, Qiang / Zhang, Fan / Wang, Wei-Wei / Gao, Jin-Ming et al. | 2019
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Thermostability enhancement of the α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense by using the anchoring-and-self-labelling-protein-tag system (ASLtag)Del Prete, Sonia / Merlo, Rosa / Valenti, Anna / Mattossovich, Rosanna / Rossi, Mosè / Carginale, Vincenzo / Supuran, Claudiu T. / Perugino, Giuseppe / Capasso, Clemente et al. | 2019
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Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitorsJin, Xiao-Yan / Chen, Hao / Li, Dong-Dong / Li, A-Liang / Wang, Wen-Yan / Gu, Wen et al. | 2019
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Probing the role of an invariant active site His in family GH1 β-glycosidasesStrazzulli, Andrea / Perugino, Giuseppe / Mazzone, Marialuisa / Rossi, Mosè / Withers, Stephen G. / Moracci, Marco et al. | 2019
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Design, synthesis and biological activity evaluation of a new class of 2,4-thiazolidinedione compounds as insulin enhancersHuiying, Zou / Guangying, Chen / Shiyang, Zhou et al. | 2019
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Kinetic and computational molecular docking simulation study of novel kojic acid derivatives as anti-tyrosinase and antioxidant agentsChen, Yan-Mei / Li, Chen / Zhang, Wen-Jing / Shi, Yan / Wen, Zi-Jie / Chen, Qing-Xi / Wang, Qin et al. | 2019
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A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from Rostellularia procumbens (L.) NeesWu, Songtao / Yang, Yanfang / Liu, Bo / Xie, Zhoutao / Xiong, Weichen / Hao, Pengfei / Xiao, Wenping / Sun, Yuan / Ai, Zhongzhu / Wu, Hezhen et al. | 2019
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Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligasesHrast, Martina / Rožman, Kaja / Ogris, Iza / Škedelj, Veronika / Patin, Delphine / Sova, Matej / Barreteau, Hélène / Gobec, Stanislav / Grdadolnik, Simona Golič / Zega, Anamarija et al. | 2019
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Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approachda Silva, Jorge Alberto Valle / Nepovimova, Eugenie / Ramalho, Teodorico Castro / Kuca, Kamil / Celmar Costa França, Tanos et al. | 2019
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Novel sulfonamide benzoquinazolinones as dual EGFR/HER2 inhibitors, apoptosis inducers and radiosensitizersSoliman, Aiten M. / Alqahtani, Ali S. / Ghorab, Mostafa M. et al. | 2019
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Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative studyIaccarino, Nunzia / Amato, Jussara / Pagano, Bruno / Di Porzio, Anna / Micucci, Matteo / Bolelli, Luca / Aldini, Rita / Novellino, Ettore / Budriesi, Roberta / Randazzo, Antonio et al. | 2019
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Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studiesAmmazzalorso, Alessandra / Carradori, Simone / Angeli, Andrea / Akdemir, Atilla / De Filippis, Barbara / Fantacuzzi, Marialuigia / Giampietro, Letizia / Maccallini, Cristina / Amoroso, Rosa / Supuran, Claudiu T. et al. | 2019
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Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinomaKassab, Shaymaa E. / Mowafy, Samar / Alserw, Aya M. / Seliem, Joustin A. / El-Naggar, Shahenda M. / Omar, Nesreen N. / Awad, Mohamed M. et al. | 2019
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Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivativeBibi, David / Shusterman, Bella / Nocentini, Alessio / Supuran, Claudiu T. / Bialer, Meir et al. | 2019
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Synthesis and biological evaluation of 3–(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer’s disease agentsHu, Yu-Heng / Yang, Jie / Zhang, Yun / Liu, Ke-Chun / Liu, Teng / Sun, Jie / Wang, Xiao-Jing et al. | 2019
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Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cellsdos Santos, Mariana Bastos / Bertholin Anselmo, Daiane / de Oliveira, Jéssica Gisleine / Jardim-Perassi, Bruna V. / Alves Monteiro, Diego / Silva, Gabriel / Gomes, Eleni / Lucia Fachin, Ana / Marins, Mozart / de Campos Zuccari, Débora Aparecida Pires et al. | 2019
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Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substancesGarcia, Andreza R. / Oliveira, Danielle M. P. / Claudia F. Amaral, Ana / Jesus, Jéssica B. / Rennó Sodero, Ana Carolina / Souza, Alessandra M. T. / Supuran, Claudiu T. / Vermelho, Alane B. / Rodrigues, Igor A. / Pinheiro, Anderson S. et al. | 2019
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Design, synthesis, molecular modelling, and biological evaluation of novel substituted pyrimidine derivatives as potential anticancer agents for hepatocellular carcinomaAhmed, Naglaa Mohamed / Youns, Mahmoud / Soltan, Moustafa Khames / Said, Ahmed Mohammed et al. | 2019
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Design and synthesis of novel pyrazolo[4,3-d]pyrimidines as potential therapeutic agents for acute lung injuryWang, Bao Shi / Huang, Xin / Chen, Liu Zeng / Liu, Ming Ming / Shi, Jing Bo et al. | 2019
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Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysisDi Paolo, Veronica / Fulci, Chiara / Rotili, Dante / Sciarretta, Francesca / Lucidi, Alessia / Morozzo della Rocca, Blasco / De Luca, Anastasia / Rosato, Antonio / Quintieri, Luigi / Caccuri, Anna Maria et al. | 2019
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Discovery and antitumor evaluation of novel inhibitors of spermine oxidaseSun, Lidan / Yang, Jianlin / Qin, Yu / Wang, Yanlin / Wu, Hongyan / Zhou, You / Cao, Chunyu et al. | 2019
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Identification of novel indole derivatives acting as inhibitors of the Keap1–Nrf2 interactionCosimelli, Barbara / Greco, Giovanni / Laneri, Sonia / Novellino, Ettore / Sacchi, Antonia / Amendola, Giorgio / Cosconati, Sandro / Bortolozzi, Roberta / Viola, Giampietro et al. | 2019
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Identification of phenazine analogue as a novel scaffold for thioredoxin reductase I inhibitors against Hep G2 cancer cell linesLiao, Jianming / Wang, Linlin / Wu, Zhongxi / Wang, Zhixiang / Chen, Jun / Zhong, Yucheng / Jiang, Feng / Lu, Yuanyuan et al. | 2019
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Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovaniNocentini, Alessio / Osman, Sameh M. / Rodrigues, Igor A. / Cardoso, Veronica S. / Alasmary, Fatmah Ali S. / AlOthman, Zeid / Vermelho, Alane B. / Gratteri, Paola / Supuran, Claudiu T. et al. | 2019
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Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitorsThacker, Pavitra S. / Shaikh, Pirpasha / Angeli, Andrea / Arifuddin, Mohammed / Supuran, Claudiu T. et al. | 2019
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The first activation study of the β-carbonic anhydrases from the pathogenic bacteria Brucella suis and Francisella tularensis with amines and amino acidsAngeli, Andrea / Del Prete, Sonia / Pinteala, Mariana / Maier, Stelian S. / Donald, William A. / Simionescu, Bogdan C. / Capasso, Clemente / Supuran, Claudiu T. et al. | 2019
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Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivativesGitto, Rosaria / De Luca, Laura / Mancuso, Francesca / Del Prete, Sonia / Vullo, Daniela / Supuran, Claudiu T. / Capasso, Clemente et al. | 2019
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Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivativesAkocak, Suleyman / Lolak, Nabih / Bua, Silvia / Nocentini, Alessio / Supuran, Claudiu T. et al. | 2019
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Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitorsSwain, Baijayantimala / Angeli, Andrea / Angapelly, Srinivas / Thacker, Pavitra S. / Singh, Priti / Supuran, Claudiu T. / Arifuddin, Mohammed et al. | 2019
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Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agentsSun, Xian-yu / Zhong, Chun-yan / Qiu, Qing-qing / Li, Zhen-wang / Liu, Mei-yu / Wang, Xin / Jin, Cheng-hao et al. | 2019
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1D NMR WaterLOGSY as an efficient method for fragment-based lead discoveryRaingeval, Claire / Cala, Olivier / Brion, Béatrice / Le Borgne, Marc / Hubbard, Roderick Eliot / Krimm, Isabelle et al. | 2019
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Synthesis, antiasthmatic, and insecticidal/antifungal activities of allosamidinsHuang, Gangliang / Huang, Hualiang et al. | 2019
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Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitorsYe, Lianbao / Zhao, Tao / Du, Wenjun / Li, Anhu / Gao, Wei / Li, Jingrong / Wang, Ling / Chen, Weiqiang et al. | 2019
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In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamideKassem, Asmaa F. / Moustafa, Gaber O. / Nossier, Eman S. / Khalaf, Hemat S. / Mounier, Marwa M. / Al-Yousef, Suliman A. / Mahmoud, Sabry Y. et al. | 2019
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Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studiesOthman, Ismail M. M. / Gad-Elkareem, Mohamed A. M. / El-Naggar, Mohamed / Nossier, Eman S. / Amr, Abd El-Galil E. et al. | 2019
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Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1Herman, Bianka Edina / Kiss, Anita / Wölfling, János / Mernyák, Erzsébet / Szécsi, Mihály / Schneider, Gyula et al. | 2019
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Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activationSu, Chang-Ming / Hou, Gui-Ge / Wang, Chun-Hua / Zhang, Hong-Qin / Yang, Cheng / Liu, Mei / Hou, Yun et al. | 2019
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10H-1,9-diazaphenothiazine and its 10-derivatives: synthesis, characterisation and biological evaluation as potential anticancer agentsMorak-Młodawska, Beata / Pluta, Krystian / Latocha, Małgorzata / Jeleń, Małgorzata / Kuśmierz, Dariusz / Suwińska, Kinga / Shkurenko, Aleksander / Czuba, Zenon / Jurzak, Magdalena et al. | 2019
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Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cellsEttari, Roberta / Pallio, Giovanni / Pizzino, Gabriele / Irrera, Natasha / Zappalà, Maria / Maiorana, Santina / Di Chio, Carla / Altavilla, Domenica / Squadrito, Francesco / Bitto, Alessandra et al. | 2019
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Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as highly selective and potent BRAFV600E and CRAF inhibitorKim, Jinwoong / Choi, Byeongha / Im, Daseul / Jung, Hoyong / Moon, Hyungwoo / Aman, Waqar / Hah, Jung-Mi et al. | 2019
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Carbazole scaffolds in cancer therapy: a review from 2012 to 2018Issa, Samar / Prandina, Anthony / Bedel, Nicolas / Rongved, Pål / Yous, Saïd / Le Borgne, Marc / Bouaziz, Zouhair et al. | 2019
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Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibitionElmeligie, Salwa / Aboul-Magd, Asmaa M. / Lasheen, Deena S. / Ibrahim, Tamer M. / Abdelghany, Tamer M. / Khojah, Sohair M. / Abouzid, Khaled A. M. et al. | 2019
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Novel 2-phenoxypyrido[3,2-b]pyrazin-3(4H)-one derivatives as potent and selective aldose reductase inhibitors with antioxidant activityHao, Xin / Qi, Gang / Ma, Hongxing / Zhu, Changjin / Han, Zhongfei et al. | 2019
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Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screeningAtatreh, Noor / Al Rawashdah, Sara / Al Neyadi, Shaikha S. / Abuhamdah, Sawsan M. / Ghattas, Mohammad A. et al. | 2019
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Anticancer sulfonamide hybrids that inhibit bladder cancer cells growth and migration as tubulin polymerisation inhibitorsLiu, Jia / Liu, Chunlai / Zhang, Xiling / Yu, Liu / Gong, Xue / Wang, Ping et al. | 2019
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New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moietyUgwuja, D. I. / Okoro, U. C. / Soman, S. S. / Soni, R. / Okafor, S. N. / Ugwu, D. I. et al. | 2019
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Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffoldRotondi, Giulia / Guglielmi, Paolo / Carradori, Simone / Secci, Daniela / De Monte, Celeste / De Filippis, Barbara / Maccallini, Cristina / Amoroso, Rosa / Cirilli, Roberto / Akdemir, Atilla et al. | 2019
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Synthesis and enzyme-based evaluation of analogues L-tyrosine thiol carboxylic acid inhibitor of metallo-β-lactamase IMP-1Khalili Arjomandi, Omid / Kavoosi, Mahboubeh / Adibi, Hadi et al. | 2019
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Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitorsNam, Yunju / Hwang, Dongkeun / Kim, Namdoo / Seo, Hong-Seog / Selim, Khalid B. / Sim, Taebo et al. | 2019
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Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Leishmania chagasiTeixeira, Bárbara Velame Ferreira / Teles, André Lacerda Braga / Silva, Suellen Gonçalves da / Brito, Camila Carane Bitencourt / Freitas, Humberto Fonseca de / Pires, Acássia Benjamim Leal / Froes, Thamires Quadros / Castilho, Marcelo Santos et al. | 2019
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Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C proteaseMaseko, Sibusiso / Padayachee, Eden / Maphumulo, Siyabonga / Govender, Thavendran / Sayed, Yasien / Maguire, Glenn / Lin, Johnson / Naicker, Tricia / Baijnath, Sooraj / Gerhardus, Kruger Hendrik et al. | 2019
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Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitorsAl-Sanea, Mohammad M. / Elkamhawy, Ahmed / Paik, Sora / Bua, Silvia / Ha Lee, So / Abdelgawad, Mohamed A. / Roh, Eun Joo / Eldehna, Wagdy M. / Supuran, Claudiu T. et al. | 2019
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Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activitySabatier, Laureano L. / Palestro, Pablo H. / Enrique, Andrea V. / Pastore, Valentina / Sbaraglini, María L. / Martín, Pedro / Gavernet, Luciana et al. | 2019
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A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activityMenden, Ariane / Hall, Davane / Paris, Daniel / Mathura, Venkatarian / Crawford, Fiona / Mullan, Michael / Crynen, Stefan / Ait-Ghezala, Ghania et al. | 2019
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Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activityKwon, Mincheol / Ko, Sung-Kyun / Jang, Mina / Kim, Gun-Hee / Ryoo, In-Ja / Son, Sangkeun / Ryu, Hyung Won / Oh, Sei-Ryang / Lee, Won-Kyu / Kim, Bo Yeon et al. | 2019
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Dual-target anti-Alzheimer’s disease agents with both iron ion chelating and monoamine oxidase-B inhibitory activityMi, Zhisheng / Gan, Bing / Yu, Sihang / Guo, Jianan / Zhang, Changjun / Jiang, Xiaoying / Zhou, Tao / Su, Jing / Bai, Renren / Xie, Yuanyuan et al. | 2019
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Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivityLangella, Emma / Alterio, Vincenzo / D’Ambrosio, Katia / Cadoni, Roberta / Winum, Jean-Yves / Supuran, Claudiu T. / Monti, Simona Maria / De Simone, Giuseppina / Di Fiore, Anna et al. | 2019
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Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approachDe Simone, Giuseppina / Di Fiore, Anna / Truppo, Emanuela / Langella, Emma / Vullo, Daniela / Supuran, Claudiu T. / Monti, Simona Maria et al. | 2019
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Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activityGuglielmi, Paolo / Secci, Daniela / Petzer, Anél / Bagetta, Donatella / Chimenti, Paola / Rotondi, Giulia / Ferrante, Claudio / Recinella, Lucia / Leone, Sheila / Alcaro, Stefano et al. | 2019
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Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrasesDistinto, Simona / Meleddu, Rita / Ortuso, Francesco / Cottiglia, Filippo / Deplano, Serenella / Sequeira, Lisa / Melis, Claudia / Fois, Benedetta / Angeli, Andrea / Capasso, Clemente et al. | 2019
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Design, synthesis, in vitro potent antiproliferative activity, and kinase inhibitory effects of new triarylpyrazole derivatives possessing different heterocycle terminal moietiesGamal El-Din, Mahmoud M. / El-Gamal, Mohammed I. / Abdel-Maksoud, Mohammed S. / Yoo, Kyung Ho / Oh, Chang-Hyun et al. | 2019
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Synthesis and biological evaluation of novel N-(piperazin-1-yl)alkyl-1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential MEK inhibitorsChen, Hao / Qiao, Chao / Miao, Ting-Ting / Li, A-Liang / Wang, Wen-Yan / Gu, Wen et al. | 2019
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Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivativesRafiq, Muhammad / Nazir, Yasir / Ashraf, Zaman / Rafique, Hummera / Afzal, Samina / Mumtaz, Amara / Hassan, Mubashir / Ali, Anser / Afzal, Khurram / Yousuf, Muhammad Rizwan et al. | 2019
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Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activitiesJaballah, Maiy Y. / Serya, Rabah A. T. / Saad, Nasser / Khojah, Sohair M. / Ahmed, Marawan / Barakat, Khaled / Abouzid, Khaled A. M. et al. | 2019
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Design and application of oral colon administration systemCheng, Hao / Huang, Shiyu / Huang, Gangliang et al. | 2019
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Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonistsLao, Kejing / Xun, Guoliang / Gou, Xingchun / Xiang, Hua et al. | 2019
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Synthesis and bioevaluation of novel steroidal isatin conjugates derived from epiandrosterone/androsteroneKe, Shaoyong / Zhang, Zhigang / Liu, Manli / Fang, Wei / Huang, Daye / Wan, Zhongyi / Zhou, Ronghua / Wang, Kaimei / Shi, Liqiao et al. | 2019
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An overview of carbonic anhydrases and membrane channels of synoviocytes in inflamed jointsJi, Min Jeong / Hong, Jeong Hee et al. | 2019
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Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticusJenis, Janar / Baiseitova, Aizhamal / Yoon, Sang Hwa / Park, Chanin / Kim, Jeong Yoon / Li, Zuo Peng / Lee, Keun Woo / Park, Ki Hun et al. | 2019
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Novel tyrosinase inhibitory peptide with free radical scavenging abilityShen, Zhiwei / Wang, Yujiao / Guo, Zhen / Tan, Tingyuan / Zhang, Yi et al. | 2019
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Exosomes in head and neck cancer. Updating and revisitingZorrilla, Samuel Rodríguez / García, Abel García / Carrión, Andrés Blanco / Vila, Pilar Gándara / Martín, Manuel Somoza / Torreira, Mercedes Gallas / Sayans, Mario Pérez et al. | 2019
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Activation of α-, β-, γ- δ-, ζ- and η- class of carbonic anhydrases with amines and amino acids: a reviewAkocak, Suleyman / Supuran, Claudiu T. et al. | 2019
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Anti-Helicobacter pylori activity of ethoxzolamideModak, Joyanta K. / Tikhomirova, Alexandra / Gorrell, Rebecca J. / Rahman, Mohammad M. / Kotsanas, Despina / Korman, Tony M. / Garcia-Bustos, Jose / Kwok, Terry / Ferrero, Richard L. / Supuran, Claudiu T. et al. | 2019
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Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFRwt-TK inhibitorZhang, Yaling / Chen, Li / Li, Xiabing / Gao, Li / Hao, Yunxia / Li, Baolin / Yan, Yaping et al. | 2019
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Synthesis and in vitro and in vivo anti-inflammatory activity of novel 4-ferrocenylchroman-2-one derivativesGuo, Wei-Yun / Chen, Liu-Zeng / Shen, Bang-Nian / Liu, Xin-Hua / Tai, Guang-Ping / Li, Qing-Shan / Gao, Li / Ruan, Ban-Feng et al. | 2019
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Extraction and derivatisation of active polysaccharidesLiu, Yang / Huang, Gangliang et al. | 2019
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