Correction (Unbekannt)
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mAbs
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13
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2021
- Aufsatz (Zeitschrift) / Elektronische Ressource
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Titel:Correction
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Erschienen in:mAbs ; 13, 1
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Verlag:
- Neue Suche nach: Taylor & Francis
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Erscheinungsdatum:01.01.2021
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DOI:
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Medientyp:Aufsatz (Zeitschrift)
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Format:Elektronische Ressource
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Sprache:Unbekannt
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Inhaltsverzeichnis – Band 13, Ausgabe 1
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Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
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Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragmentsNannini, Francesco / Senicar, Lenart / Parekh, Farhaan / Kong, Khai J. / Kinna, Alexander / Bughda, Reyisa / Sillibourne, James / Hu, Xihao / Ma, Biao / Bai, Yuchen et al. | 2021
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Discovery-stage identification of drug-like antibodies using emerging experimental and computational methodsMakowski, Emily K. / Wu, Lina / Gupta, Priyanka / Tessier, Peter M. et al. | 2021
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A platform-agnostic, function first-based antibody discovery strategy using plasmid-free mammalian expression of antibodiesZhang, Ruijun / Prabakaran, Ponraj / Yu, Xiaocong / Mackness, Brian C. / Boudanova, Ekaterina / Hopke, Joern / Sancho, Jose / Saleh, Jacqueline / Cho, HyunSuk / Zhang, Ningning et al. | 2021
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Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoproteinHarshbarger, Wayne / Abeyrathne, Priyanka D. / Tian, Sai / Huang, Ying / Chandramouli, Sumana / Bottomley, Matthew James / Malito, Enrico et al. | 2021
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Enhancing the multi-attribute method through an automated and high-throughput sample preparationSitasuwan, Pongkwan / Powers, Thomas W. / Medwid, Tiffany / Huang, Yuting / Bare, Bradley / Lee, L. Andrew et al. | 2021
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Antibody-mediated delivery of LIGHT to the tumor boosts natural killer cells and delays tumor progressionStringhini, Marco / Mock, Jacqueline / Fontana, Vanessa / Murer, Patrizia / Neri, Dario et al. | 2021
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Identification of critical chemical modifications by size exclusion chromatography of stressed antibody-target complexes with competitive bindingShi, Rachel Liuqing / Xiao, Gang / Dillon, Thomas M. / McAuley, Arnold / Ricci, Margaret S. / Bondarenko, Pavel V. et al. | 2021
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Data mining patented antibody sequencesKrawczyk, Konrad / Buchanan, Andrew / Marcatili, Paolo et al. | 2021
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Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid proteinHodge, Curtis D. / Rosenberg, Daniel. J. / Grob, Patricia / Wilamowski, Mateusz / Joachimiak, Andrzej / Hura, Greg L. / Hammel, Michal et al. | 2021
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Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1Chen, Weimin / Pandey, Madhu / Sun, Hong / Rolong, Andrea / Cao, Mingyan / Liu, Dengfeng / Wang, Jihong / Zeng, Lingmin / Hunter, Alan / Lin, Shihua et al. | 2021
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501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitroLiu, Haolin / Wei, Pengcheng / Zhang, Qianqian / Chen, Zhongzhou / Aviszus, Katja / Downing, Walter / Peterson, Shelley / Reynoso, Lyndon / Downey, Gregory P. / Frankel, Stephen K. et al. | 2021
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Immunogenicity risk assessment for biotherapeutics through in vitro detection of CD134 and CD137 on T helper cellsCohen, Sivan / Myneni, Srividya / Batt, Anna / Guerrero, Joyce / Brumm, Jochen / Chung, Shan et al. | 2021
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Developments and opportunities in continuous biopharmaceutical manufacturingKhanal, Ohnmar / Lenhoff, Abraham M. et al. | 2021
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Protective antibodies against human parainfluenza virus type 3 infectionBoonyaratanakornkit, Jim / Singh, Suruchi / Weidle, Connor / Rodarte, Justas / Bakthavatsalam, Ramasamy / Perkins, Jonathan / Stewart-Jones, Guillaume B.E. / Kwong, Peter D. / McGuire, Andrew T. / Pancera, Marie et al. | 2021
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Animal immunization merges with innovative technologies: A new paradigm shift in antibody discoveryPrabakaran, Ponraj / Rao, Sambasiva P / Wendt, Maria et al. | 2021
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A T cell redirection platform for co-targeting dual antigens on solid tumorsEnderle, Leonie / Shalaby, Karim H. / Gorelik, Maryna / Weiss, Alexander / Blazer, Levi L. / Paduch, Marcin / Cardarelli, Lia / Kossiakoff, Anthony / Adams, Jarrett J. / Sidhu, Sachdev S. et al. | 2021
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A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and preventionKwon, Young D. / Asokan, Mangaiarkarasi / Gorman, Jason / Zhang, Baoshan / Liu, Qingbo / Louder, Mark K. / Lin, Bob C. / McKee, Krisha / Pegu, Amarendra / Verardi, Raffaello et al. | 2021
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Host cell protein detection gap risk mitigation: quantitative IAC-MS for ELISA antibody reagent coverage determinationWaldera-Lupa, Daniel M. / Jasper, Yvonne / Köhne, Pia / Schwichtenhövel, Ronja / Falkenberg, Heiner / Flad, Thomas / Happersberger, Peter / Reisinger, Bernd / Dehghani, Alireza / Moussa, Roland et al. | 2021
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Host cell protein profiling of commercial therapeutic protein drugs as a benchmark for monoclonal antibody-based therapeutic protein developmentMolden, Rosalynn / Hu, Mengqi / Yen E, Sook / Saggese, Diana / Reilly, James / Mattila, John / Qiu, Haibo / Chen, Gang / Bak, Hanne / Li, Ning et al. | 2021
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Characterizing and understanding the formation of cysteine conjugates and other by-products in a random, lysine-linked antibody drug conjugateQiu, Difei / Huang, Yande / Chennamsetty, Naresh / Miller, Scott A. / Hay, Michael et al. | 2021
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TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHLMalik-Chaudhry, Harbani K. / Prabhakar, Kirthana / Ugamraj, Harshad S. / Boudreau, Andrew A. / Buelow, Benjamin / Dang, Kevin / Davison, Laura M. / Harris, Katherine E. / Jorgensen, Brett / Ogana, Heather et al. | 2021
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The influence of antibody engineering on Fc conformation and Fc receptor binding properties: Analysis of FcRn-binding engineered antibodies and an Fc fusion proteinSuzuki, Takuo / Hashii, Noritaka / Tada, Minoru / Ishii-Watabe, Akiko et al. | 2021
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Targeting cancer with antibody-drug conjugates: Promises and challengesDean, Alexis Q. / Luo, Shen / Twomey, Julianne D. / Zhang, Baolin et al. | 2021
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Targeting and pharmacology of an anti-IL13Rα2 antibody and antibody-drug conjugate in a melanoma xenograft modelGupta, Parul / Jiang, Ziyue Karen / Yang, Bing / Manzuk, Lisa / Rosfjord, Edward / Yao, Johnny / Lemon, Luanna / Noorbehesht, Kavon / David, John / Puthenveetil, Sujiet et al. | 2021
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Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reductionPark, Seo-Young / Egan, Susan / Cura, Anthony J. / Aron, Kathryn L. / Xu, Xuankuo / Zheng, Mengyuan / Borys, Michael / Ghose, Sanchayita / Li, Zhengjian / Lee, Kyongbum et al. | 2021
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Ten years in the making: application of CrossMab technology for the development of therapeutic bispecific antibodies and antibody fusion proteinsSurowka, Marlena / Schaefer, Wolfgang / Klein, Christian et al. | 2021
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Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancerXiang, Hong / Chan, Abigael G. / Ahene, Ago / Bellovin, David I. / Deng, Rong / Hsu, Amy W. / Jeffry, Ursula / Palencia, Servando / Powers, Janine / Zanghi, James et al. | 2021
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Identification of a CE-SDS shoulder peak as disulfide-linked fragments from common CH2 cleavages in IgGs and IgG-like bispecific antibodiesCao, Mingyan / Jiao, Yang / Parthemore, Conner / Korman, Samuel / Ma, Jiao / Hunter, Alan / Kilby, Greg / Chen, Xiaoyu et al. | 2021
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Nonclinical safety evaluation, pharmacokinetics, and target engagement of Lu AF82422, a monoclonal IgG1 antibody against alpha-synuclein in development for treatment of synucleinopathiesFjord-Larsen, Lone / Thougaard, Annemette / Wegener, Karen Malene / Christiansen, Joan / Larsen, Frank / Schrøder-Hansen, Lise Maj / Kaarde, Marianne / Ditlevsen, Dorte Kornerup et al. | 2021
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Agonistic nanobodies and antibodies to human VISTAMa, Yu-Heng Vivian / Sparkes, Amanda / Romão, Ema / Saha, Shrayasee / Gariépy, Jean et al. | 2021
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Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal modelsKumar, Sujatha / Ghosh, Srimoyee / Sharma, Geeta / Wang, Zebin / Kehry, Marilyn R. / Marino, Margaret H. / Neben, Tamlyn Y. / Lu, Sharon / Luo, Shouqi / Roberts, Simon et al. | 2021
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Identification of critical chemical modifications and paratope mapping by size exclusion chromatography of stressed antibody-target complexesBondarenko, Pavel V. / Nichols, Andrew C. / Xiao, Gang / Shi, Rachel Liuqing / Chan, Pik Kay / Dillon, Thomas M / Garces, Fernando / Semin, David J. / Ricci, Margaret S. et al. | 2021
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A bivalent, bispecific Dab-Fc antibody molecule for dual targeting of HER2 and HER3Rau, Alexander / Kocher, Katharina / Rommel, Mirjam / Kühl, Lennart / Albrecht, Maximilian / Gotthard, Hannes / Aschmoneit, Nadine / Noll, Bettina / Olayioye, Monilola A. / Kontermann, Roland E. et al. | 2021
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A non-clinical comparative study of IL-23 antibodies in psoriasisZhou, Li / Wang, Yibing / Wan, Qi / Wu, Fei / Barbon, Jeffrey / Dunstan, Robert / Gauld, Stephen / Konrad, Mark / Leys, Laura / McCarthy, Richard et al. | 2021
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Structure-based charge calculations for predicting isoelectric point, viscosity, clearance, and profiling antibody therapeuticsThorsteinson, Nels / Gunn, John R. / Kelly, Kenneth / Long, Will / Labute, Paul et al. | 2021
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Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody librariesTeixeira, Andre Azevedo Reis / Erasmus, Michael Frank / D’Angelo, Sara / Naranjo, Leslie / Ferrara, Fortunato / Leal-Lopes, Camila / Durrant, Oliver / Galmiche, Cecile / Morelli, Aleardo / Scott-Tucker, Anthony et al. | 2021
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Current strategies for detecting functional convergence across B-cell receptor repertoiresRaybould, Matthew I. J. / Rees, Anthony R. / Deane, Charlotte M. et al. | 2021
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Coming together at the hinges: Therapeutic prospects of IgG3Chu, Thach H. / Patz, Edward F.Jr / Ackerman, Margaret E. et al. | 2021
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Off-target binding of an anti-amyloid beta monoclonal antibody to platelet factor 4 causes acute and chronic toxicity in cynomolgus monkeysLoberg, Lise I. / Chhaya, Meha / Ibraghimov, Alexander / Tarcsa, Edit / Striebinger, Andreas / Popp, Andreas / Huang, Lili / Oellien, Frank / Barghorn, Stefan et al. | 2021
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Targeting cancer homing into the lymph node with a novel anti-CCR7 therapeutic antibody: the paradigm of CLLCuesta-Mateos, Carlos / Juárez-Sánchez, Raquel / Mateu-Albero, Tamara / Loscertales, Javier / Mol, Wim / Terrón, Fernando / Muñoz-Calleja, Cecilia et al. | 2021
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Identifying biophysical assays and in silico properties that enrich for slow clearance in clinical-stage therapeutic antibodiesGrinshpun, Boris / Thorsteinson, Nels / Pereira, Joao NS / Rippmann, Friedrich / Nannemann, David / Sood, Vanita D. / Fomekong Nanfack, Yves et al. | 2021
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Stability of a high-concentration monoclonal antibody solution produced by liquid–liquid phase separationBramham, Jack E. / Davies, Stephanie A. / Podmore, Adrian / Golovanov, Alexander P. et al. | 2021
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Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumorsWingert, Susanne / Reusch, Uwe / Knackmuss, Stefan / Kluge, Michael / Damrat, Michael / Pahl, Jens / Schniegler-Mattox, Ute / Mueller, Thomas / Fucek, Ivica / Ellwanger, Kristina et al. | 2021
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Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometryLippold, Steffen / Knaupp, Alexander / de Ru, Arnoud H. / Tjokrodirijo, Rayman T. N. / van Veelen, Peter A. / van Puijenbroek, Erwin / de Taeye, Steven W. / Reusch, Dietmar / Vidarsson, Gestur / Wuhrer, Manfred et al. | 2021
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Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumorsRoot, Adam R. / Guntas, Gurkan / Katragadda, Madan / Apgar, James R. / Narula, Jatin / Chang, Chew Shun / Hanscom, Sara / McKenna, Matthew / Wade, Jason / Meade, Caryl et al. | 2021
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Antibodies to watch in 2021Kaplon, Hélène / Reichert, Janice M. et al. | 2021
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Ensembles in solution as a new paradigm for antibody structure prediction and designFernández-Quintero, Monica L. / Georges, Guy / Varga, Janos M. / Liedl, Klaus R. et al. | 2021
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An efficient system for bioconjugation based on a widely applicable engineered O-glycosylation tagMurray, Thomas V. / Kozakowska-McDonnell, Kasia / Tibbles, Adam / Taylor, Annabel / Higazi, Daniel / Rossy, Emmanuel / Rossi, Alessandra / Genapathy, Sivaneswary / Tamburrino, Giulia / Rath, Nicola et al. | 2021
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Effect of variable domain charge on in vitro and in vivo disposition of monoclonal antibodiesLiu, Shufang / Verma, Ashwni / Kettenberger, Hubert / Richter, Wolfgang F. / Shah, Dhaval K. et al. | 2021
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Isolation and characterization of monoclonal antibodies against human carbonic anhydrase-IXLenferink, Anne E.G. / McDonald, Paul C. / Cantin, Christiane / Grothé, Suzanne / Gosselin, Mylene / Baardsnes, Jason / Banville, Myriam / Lachance, Paul / Robert, Alma / Cepero-Donates, Yuneivy et al. | 2021
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Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibodyFalck, David / Thomann, Marco / Lechmann, Martin / Koeleman, Carolien A. M. / Malik, Sebastian / Jany, Cordula / Wuhrer, Manfred / Reusch, Dietmar et al. | 2021
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Rational selection of building blocks for the assembly of bispecific antibodiesGong, Danyang / Riley, Timothy P. / Bzymek, Krzysztof P. / Correia, Ana R. / Li, Danqing / Spahr, Christopher / Robinson, John H. / Case, Ryan B. / Wang, Zhulun / Garces, Fernando et al. | 2021
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Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoVJiang, Wen / Wang, Junchao / Jiao, Shasha / Gu, Chenjian / Xu, Wei / Chen, Ben / Wang, Rongjuan / Chen, Huilin / Xie, Youhua / Wang, An et al. | 2021
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Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studiesValtonen, Salla / Vuorinen, Emmiliisa / Eskonen, Ville / Malakoutikhah, Morteza / Kopra, Kari / Härmä, Harri et al. | 2021
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Impact of IgG subclass on molecular properties of monoclonal antibodiesTang, Yu / Cain, Paul / Anguiano, Victor / Shih, James J. / Chai, Qing / Feng, Yiqing et al. | 2021
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Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIXSheff, Joey G. / Kelly, John F. / Robotham, Anna / Sulea, Traian / Malenfant, Félix / L’Abbé, Denis / Duchesne, Mélanie / Pelletier, Alex / Lefebvre, Jean / Acel, Andrea et al. | 2021
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Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancerSchofield, Darren J. / Percival-Alwyn, Jennifer / Rytelewski, Mateusz / Hood, John / Rothstein, Raymond / Wetzel, Leslie / McGlinchey, Kelly / Adjei, Grace / Watkins, Amanda / Machiesky, LeeAnn et al. | 2021
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Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor responseDela Cruz Chuh, Josefa / Go, MaryAnn / Chen, Yvonne / Guo, Jun / Rafidi, Hanine / Mandikian, Danielle / Sun, Yonglian / Lin, Zhonghua / Schneider, Kellen / Zhang, Pamela et al. | 2021
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Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activationWei, Bingchuan / Gao, Xuan / Cadang, Lance / Izadi, Saeed / Liu, Peilu / Zhang, Hui-Min / Hecht, Elizabeth / Shim, Jeongsup / Magill, Gordon / Pabon, Juan Rincon et al. | 2021
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Calculation of therapeutic antibody viscosity with coarse-grained models, hydrodynamic calculations and machine learning-based parametersLai, Pin-Kuang / Swan, James W. / Trout, Bernhardt L. et al. | 2021
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Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer modelsRabia, Emilia / Garambois, Véronique / Hubert, Julie / Bruciamacchie, Marine / Pirot, Nelly / Delpech, Hélène / Broyon, Morgane / Theillet, Charles / Colombo, Pierre-Emmanuel / Vie, Nadia et al. | 2021
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Development of potent and effective synthetic SARS-CoV-2 neutralizing nanobodiesStefan, Maxwell A. / Light, Yooli K. / Schwedler, Jennifer L. / McIlroy, Peter R. / Courtney, Colleen M. / Saada, Edwin A. / Thatcher, Christine E. / Phillips, Ashlee M. / Bourguet, Feliza A. / Mageeney, Catherine M. et al. | 2021
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Quantification of natural abundance NMR data differentiates the solution behavior of monoclonal antibodies and their fragmentsBan, David / Rice, Cory T. / McCoy, Mark A. et al. | 2021
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Antibody mix-and-read assays based on fluorescence intensity probesPatil, Ujwal / Goyal, Atul / Vu, Binh / Liu, Yanyun / Maranholkar, Vijay / Kourentzi, Katerina / Briggs, James M. / Willson, Richard C. et al. | 2021
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Development of a fully canine anti-canine CTLA4 monoclonal antibody for comparative translational research in dogs with spontaneous tumorsMason, Nicola J. / Chester, Nicholas / Xiong, Ailian / Rotolo, Antonia / Wu, Ying / Yoshimoto, Sho / Glassman, Patrick / Gulendran, Gayathri / Siegel, Don L. et al. | 2021
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The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearanceOpolka-Hoffmann, Eugenia / Jordan, Gregor / Otteneder, Michael / Kieferle, Robin / Lechmann, Martin / Winter, Gerhard / Staack, Roland F. et al. | 2021
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Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecificsChing, Kathryn H. / Berg, Kimberley / Reynolds, Kevin / Pedersen, Darlene / Macias, Alba / Abdiche, Yasmina N. / Harriman, William D. / Leighton, Philip A. et al. | 2021
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Innovative approaches to biologic development on the trail of CT-P13: biosimilars, value-added medicines, and biobettersKim, HoUng / Alten, Rieke / Cummings, Fraser / Danese, Silvio / D’Haens, Geert / Emery, Paul / Ghosh, Subrata / Gilletta de Saint Joseph, Cyrielle / Lee, JongHyuk / Lindsay, James O. et al. | 2021
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A computational method for immune repertoire mining that identifies novel binders from different clonotypes, demonstrated by identifying anti-pertussis toxoid antibodiesRichardson, Eve / Galson, Jacob D. / Kellam, Paul / Kelly, Dominic F. / Smith, Sarah E. / Palser, Anne / Watson, Simon / Deane, Charlotte M. et al. | 2021
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Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibodyCampbell, Sharon M. / DeBartolo, Joseph / Apgar, James R. / Mosyak, Lydia / McManus, Virginie / Beyer, Sonia / Bennett, Eric M. / Lambert, Matthew / Cunningham, Orla et al. | 2021
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Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2Lim, Shion A. / Gramespacher, Josef A. / Pance, Katarina / Rettko, Nicholas J. / Solomon, Paige / Jin, Jing / Lui, Irene / Elledge, Susanna K. / Liu, Jia / Bracken, Colton J. et al. | 2021
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Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivoMester, Simone / Evers, Mitchell / Meyer, Saskia / Nilsen, Jeannette / Greiff, Victor / Sandlie, Inger / Leusen, Jeanette / Andersen, Jan Terje et al. | 2021
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Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapyWaldhauer, Inja / Gonzalez-Nicolini, Valeria / Freimoser-Grundschober, Anne / Nayak, Tapan K / Fahrni, Linda / Hosse, Ralf J. / Gerrits, Danny / Geven, Edwin J. W. / Sam, Johannes / Lang, Sabine et al. | 2021
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N-terminal selective conjugation method widens the therapeutic window of antibody–drug conjugates by improving tolerability and stabilityKo, Min Ji / Song, Daehae / Kim, Juhee / Kim, Jae Yong / Eom, Jaehyun / Sung, Byungje / Son, Yong-Gyu / Kim, Young Min / Lee, Sang Hoon / You, Weon-Kyoo et al. | 2021
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A human antibody of potent efficacy against SARS-CoV-2 in rhesus macaques showed strong blocking activity to B.1.351Gu, Chunyin / Cao, Xiaodan / Wang, Zongda / Hu, Xue / Yao, Yanfeng / Zhou, Yiwu / Liu, Peipei / Liu, Xiaowu / Gao, Ge / Hu, Xiao et al. | 2021
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Challenges of non-clinical safety testing for biologics: A Report of the 9th BioSafe European Annual General Membership MeetingKissner, Thomas / Blaich, Guenter / Baumann, Andreas / Kronenberg, Sven / Hey, Adam / Kiessling, Andrea / Schmitt, Petra M. / Driessen, Wouter / Carrez, Chantal / Kramer, Daniel et al. | 2021
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Animal- versus in vitro-derived antibodies: avoiding the extremesBradbury, Andrew R.M. / Dübel, Stefan / Knappik, Achim / Plückthun, Andreas et al. | 2021
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Antibody blockade of CD96 by distinct molecular mechanismsLee, Peter S. / Chau, Bryant / Barman, Ishita / Bee, Christine / Jashnani, Aarti / Hogan, Jason M. / Aguilar, Barbara / Dollinger, Gavin / Rajpal, Arvind / Strop, Pavel et al. | 2021
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Viro-antibody therapy: engineering oncolytic viruses for genetic delivery of diverse antibody-based biotherapeuticsKontermann, Roland E. / Ungerechts, Guy / Nettelbeck, Dirk M. et al. | 2021
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Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysisChang, Hsueh-Yuan / Wu, Shengjia / Li, Yingyi / Zhang, Wanying / Burrell, Matthew / Webster, Carl I. / Shah, Dhaval K. et al. | 2021
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Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodiesRouet, Romain / Mazigi, Ohan / Walker, Gregory J. / Langley, David B. / Sobti, Meghna / Schofield, Peter / Lenthall, Helen / Jackson, Jennifer / Ubiparipovic, Stephanie / Henry, Jake Y. et al. | 2021
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Correction| 2021
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An integrated approach for characterizing immunogenic responses toward a bispecific antibodyCohen, Sivan / Chung, Shan / Spiess, Christoph / Lundin, Victor / Stefanich, Eric / Laing, Steven T. / Clark, Vanessa / Brumm, Jochen / Zhou, Ying / Huang, Catherine et al. | 2021
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Highly sensitive detection of antibody nonspecific interactions using flow cytometryMakowski, Emily K. / Wu, Lina / Desai, Alec A. / Tessier, Peter M. et al. | 2021
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The therapeutic potential of sialylated Fc domains of human IgGPleass, Richard J. et al. | 2021
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Development of a robust and semi-automated two-step antibody purification processYang, Xiaomin / Yuan, Richard / Garcia, Christopher / Berry, Jessica / Foster, Denisa / He, Dongmei / Zhang, Gui-Feng / Jones, Bryan E. et al. | 2021
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Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab librariesBhatta, Pallavi / Whale, Kevin D. / Sawtell, Amy K. / Thompson, Clare L. / Rapecki, Stephen E. / Cook, David A. / Twomey, Breda M. / Mennecozzi, Milena / Starkie, Laura E. / Barry, Emily M. C. et al. | 2021
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In memoriam: Jefferson FooteWard, E. Sally / Jones, Peter / Buss, Tim / Rada, Cristina / Winter, Gregory / Willson, Richard et al. | 2021
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Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitopeWong, Wing Ki / Robinson, Sarah A. / Bujotzek, Alexander / Georges, Guy / Lewis, Alan P. / Shi, Jiye / Snowden, James / Taddese, Bruck / Deane, Charlotte M. et al. | 2021
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One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeuticsChen, Wei / Yang, Fan / Wang, Carole / Narula, Jatin / Pascua, Edward / Ni, Irene / Ding, Sheng / Deng, Xiaodi / Chu, Matthew Ling-Hon / Pham, Amber et al. | 2021
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Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose controlLiu, Qiang / Garg, Pankaj / Hasdemir, Burcu / Wang, Linya / Tuscano, Emily / Sever, Emily / Keane, Erica / Hernandez, Ana G Lujan / Yuan, Tom Z. / Kwan, Eric et al. | 2021
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Collecting antibodies and large molecule biomarkers in mouse interstitial brain fluid: a comparison of microdialysis and cerebral open flow microperfusionLe Prieult, Florie / Barini, Erica / Laplanche, Loic / Schlegel, Kerstin / Mezler, Mario et al. | 2021
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An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeuticsFurtmann, Norbert / Schneider, Marion / Spindler, Nadja / Steinmann, Bjoern / Li, Ziyu / Focken, Ingo / Meyer, Joachim / Dimova, Dilyana / Kroll, Katja / Leuschner, Wulf Dirk et al. | 2021
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Accurate determination of epitope for antibodies with unknown 3D structuresTahir, Shifa / Bourquard, Thomas / Musnier, Astrid / Jullian, Yann / Corde, Yannick / Omahdi, Zakaria / Mathias, Laetitia / Reiter, Eric / Crépieux, Pascale / Bruneau, Gilles et al. | 2021
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Allometric scaling of therapeutic monoclonal antibodies in preclinical and clinical settingsGermovsek, Eva / Cheng, Ming / Giragossian, Craig et al. | 2021
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Selective depletion of radiolabeled HER2-specific antibody for contrast improvement during PETKhare, Priyanka / Sun, Wei / Ramakrishnan, Sreevidhya / Swiercz, Rafal / Hao, Guiyang / Lo, Su-Tang / Nham, Kien / Sun, Xiankai / Ober, Raimund J. / Ward, E. Sally et al. | 2021
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Versatile and rapid microfluidics-assisted antibody discoveryGaa, Ramona / Menang-Ndi, Emmanuel / Pratapa, Shruti / Nguyen, Christine / Kumar, Satyendra / Doerner, Achim et al. | 2021
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Novel chimeric monoclonal antibodies that block fentanyl effects and alter fentanyl biodistribution in miceBan, Bhupal / Barrientos, Rodell C. / Oertel, Therese / Komla, Essie / Whalen, Connor / Sopko, Megan / You, Yingjian / Banerjee, Partha / Sulima, Agnieszka / Jacobson, Arthur E. et al. | 2021
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Differences in human IgG1 and IgG4 S228P monoclonal antibodies viscosity and self-interactions: Experimental assessment and computational predictions of domain interactionsLai, Pin-Kuang / Ghag, Gaurav / Yu, Yao / Juan, Veronica / Fayadat-Dilman, Laurence / Trout, Bernhardt L. et al. | 2021
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Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichmentWhite, Ian / Tamot, Ninkka / Doddareddy, Rajitha / Ho, Jason / Jiao, Qun / Harvilla, Paul B. / Yang, Tong-Yuan / Geist, Brian / Borrok, M. Jack / Truppo, Matthew D. et al. | 2021
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Polyreactivity and polyspecificity in therapeutic antibody development: risk factors for failure in preclinical and clinical development campaignsCunningham, Orla / Scott, Martin / Zhou, Zhaohui Sunny / Finlay, William J.J. et al. | 2021