Human‐Based In Vitro Brain Endothelial Cell Models (Englisch)
- Neue Suche nach: Wilson, Hannah K.
- Neue Suche nach: Shusta, Eric V.
- Neue Suche nach: Di, Li
- Neue Suche nach: Kerns, Edward H.
- Neue Suche nach: Wilson, Hannah K.
- Neue Suche nach: Shusta, Eric V.
In:
Blood‐Brain Barrier in Drug Discovery
: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs
;
238-273
;
2015
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ISBN:
- Aufsatz/Kapitel (Buch) / Elektronische Ressource
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Titel:Human‐Based In Vitro Brain Endothelial Cell Models
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Beteiligte:Di, Li ( Herausgeber:in ) / Kerns, Edward H. ( Herausgeber:in ) / Wilson, Hannah K. ( Autor:in ) / Shusta, Eric V. ( Autor:in )
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Erschienen in:Blood‐Brain Barrier in Drug Discovery : Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs ; 238-273
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Verlag:
- Neue Suche nach: John Wiley & Sons, Inc
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Erscheinungsort:Hoboken, NJ
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Erscheinungsdatum:30.01.2015
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Format / Umfang:36 pages
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ISBN:
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DOI:
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Medientyp:Aufsatz/Kapitel (Buch)
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Format:Elektronische Ressource
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Sprache:Englisch
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Schlagwörter:
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Datenquelle:
Inhaltsverzeichnis E-Book
Die Inhaltsverzeichnisse werden automatisch erzeugt und basieren auf den im Index des TIB-Portals verfügbaren Einzelnachweisen der enthaltenen Beiträge. Die Anzeige der Inhaltsverzeichnisse kann daher unvollständig oder lückenhaft sein.
- 1
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Introduction and OverviewDi, Li / Kerns, Edward H. et al. | 2015
- 5
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Pharmacokinetics of CNS PenetrationReichel, Andreas et al. | 2015
- 42
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Free Drug Hypothesis for CNS Drug CandidatesLiu, Xingrong / Chen, Cuiping et al. | 2015
- 66
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Species Differences and Impact of Disease State on BBBNicolas, Jean‐Marie et al. | 2015
- 95
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Passive Diffusion Permeability of the BBB—Examples and SARSummerfield, Scott / Jeffrey, Phil / Sahi, Jasminder / Chen, Liangfu et al. | 2015
- 113
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Establishment of P‐Glycoprotein Structure–Transport Relationships to Optimize CNS Exposure in Drug DiscoveryHochman, Jerome H. / Ha, Sookhee N. / Sheridan, Robert P. et al. | 2015
- 125
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Uptake Transport at the BBB—Examples and SARCheng, Ziqiang / Liu, Qian et al. | 2015
- 146
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Transport of Protein and Antibody Therapeutics Across the Blood–Brain BarrierPardridge, William M. et al. | 2015
- 167
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In Silico Tools for Predicting Brain Exposure of DrugsChen, Hongming / Winiwarter, Susanne / Engkvist, Ola et al. | 2015
- 188
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In Vitro Assays for Assessing BBB PermeabilityAvdeef, Alex / Deli, Mária A. / Neuhaus, Winfried et al. | 2015
- 238
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Human‐Based In Vitro Brain Endothelial Cell ModelsWilson, Hannah K. / Shusta, Eric V. et al. | 2015
- 274
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Methods for Assessing Brain BindingDi, Li / Chang, Cheng et al. | 2015
- 284
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In Vivo Studies of Brain Exposure in Drug DiscoveryKerns, Edward H. et al. | 2015
- 296
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PBPK Modeling Approach for Predictions of Human CNS Drug Brain Distributionde Lange, Elizabeth C.M. et al. | 2015
- 324
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PK/PD Modeling of CNS Drug CandidatesGabrielsson, Johan / Hjorth, Stephan / Peletier, Lambertus A. et al. | 2015
- 351
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Microdialysis to Assess Free Drug Concentration in BrainKielbasa, William / Stratford, Robert E. Jr. et al. | 2015
- 365
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Imaging Techniques for Central Nervous System (CNS) Drug DiscoveryZhang, Lei / Villalobos, Anabella et al. | 2015
- 385
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Designing CNS Drugs for Optimal Brain ExposureRankovic, Zoran et al. | 2015
- 425
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Case Studies of CNS Drug Optimization—Medicinal Chemistry and CNS Biology PerspectivesHodgetts, Kevin J. et al. | 2015
- 446
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Designing Peripheral Drugs for Minimal Brain ExposureBungay, Peter / Bagal, Sharan / Pike, Andy et al. | 2015
- 463
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Case Studies of Non‐CNS Drugs to Minimize Brain Penetration—Nonsedative AntihistaminesCrowe, Andrew et al. | 2015
- 483
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Case Study 1Laurenza, Antonio / Ferry, Jim / Yang, Haichen / Hibi, Shigeki / Hanada, Takahisa / Satlin, Andrew et al. | 2015
- 505
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Case Study 2Bundgaard, Christoffer / Pehrson, Alan L. / Sánchez, Connie / Bang‐Andersen, Benny et al. | 2015
- 521
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Brain Delivery Using NanotechnologyHuile Gao / Jiang, Xinguo et al. | 2015
- 535
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Intranasal Delivery to the Central Nervous SystemIllum, Lisbeth et al. | 2015
- 567
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Future PerspectivesAbbott, N. Joan et al. | 2015
- 580
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Index| 2015
- a1
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Supplementary Images| 2015
- i
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Front Matter| 2015