Refined assessment and perspectives on the cumulative risk resulting from the dietary exposure to pesticide residues in the Danish population (Englisch)
- Neue Suche nach: Larsson, M.O.
- Neue Suche nach: Laporte, F.
- Neue Suche nach: Bjerre, N.
- Neue Suche nach: Nielsen, V.S.
- Neue Suche nach: Cedergreen, N.
- Neue Suche nach: Larsson, M.O.
- Neue Suche nach: Laporte, F.
- Neue Suche nach: Bjerre, N.
- Neue Suche nach: Nielsen, V.S.
- Neue Suche nach: Cedergreen, N.
In:
Toxicology letters
;
295
, s1
;
S139
;
2018
-
ISSN:
- Aufsatz (Zeitschrift) / Print
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Titel:Refined assessment and perspectives on the cumulative risk resulting from the dietary exposure to pesticide residues in the Danish population
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Beteiligte:Larsson, M.O. ( Autor:in ) / Laporte, F. ( Autor:in ) / Bjerre, N. ( Autor:in ) / Nielsen, V.S. ( Autor:in ) / Cedergreen, N. ( Autor:in )
-
Erschienen in:Toxicology letters ; 295, s1 ; S139
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Verlag:
- Neue Suche nach: Elsevier Science B.V., Amsterdam.
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Erscheinungsdatum:01.01.2018
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Format / Umfang:S139
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ISSN:
-
Medientyp:Aufsatz (Zeitschrift)
-
Format:Print
-
Sprache:Englisch
- Neue Suche nach: 363.179
- Weitere Informationen zu Dewey Decimal Classification
-
Klassifikation:
DDC: 363.179 -
Datenquelle:
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Inhaltsverzeichnis – Band 295, Ausgabe s1
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- I
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Author Index| 2018
- iii
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EUROTOX Contents| 2018
- S2
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Risk assessment of chemical mixtures – Regulatory requirements and current scientific approachesSolecki, R. et al. | 2018
- S3
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Aggregate and cumulative exposure of bisphenols from food and personal care products: A hands-on trainingKarrer, C. / Delmaar, C. / Bokkers, B. / Hungerbühler, K. / von Goetz, N. et al. | 2018
- S4
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Presentation of the EFSA WEB app based on PROASTCortinas Abrahantes, J. et al. | 2018
- S5
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Developing TK databases and tools to support food safety assessmentDorne, J.-L.C.M. / Amzal, B. / Quignot, N. / Wiecek, W. / Bechaux, C. / Darney, K. / Grech, A. / Brochot, C. / Beaudouin, R. / Bois, F. et al. | 2018
- S7
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Kidney-based in vitro models for toxicity testingJennings, P. et al. | 2018
- S8
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Beyond the Chip: Development and application of a micro-physiological flux analyzerNahmias, Y. et al. | 2018
- S9
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Scientific issues that need to be addressed for a successful read-across predictionCronin, M.T.D. et al. | 2018
- S10
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The OECD framework for AOP Development and the supporting toolsGourmelon, A. et al. | 2018
- S12
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D – Adverse Outcome Pathways are the future for regulatory toxicology| 2018
- S15
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A microfluidic intestinal model to investigate altered drug behavior under disease conditionsMoisan, A. et al. | 2018
- S16
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In vitro alternatives: progress, challenges and opportunitiesKimber, I. et al. | 2018
- S17
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Ensuring validity of in vitro replacements. Case study 2 - agrochemicalsBotham, P.A. et al. | 2018
- S18
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Pesticide-induced immunotoxicity: the experience at EFSATerron, A. et al. | 2018
- S20
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The use of in vitro and in vivo pharmacology and safety data to set safe starting doses for FIH studies with monoclonal antibodiesde Haan, L. et al. | 2018
- S21
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Advanced hepatic drug safety assessment: 3D & microphysiological systemsWilliams, D.P. et al. | 2018
- S22
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How oligonucleotides can be exploited as therapeuticsAartsma-Rus, A. et al. | 2018
- S23
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Non-clinical aspects of oligonucleotide drug development: A regulator's perspectiveJones, D.R. et al. | 2018
- S24
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A human brain microphysiological iPSC-derived system to study neurotoxicityHogberg, H.T. / Barreras, P. / Chesnut, M. / Gama, L. / Harris, G. / Pardo, C.A. / Smirnova, L. / Zhong, X. / Hartung, T. / Pamies, D. et al. | 2018
- S25
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In vitro models for predictive immunological testing of nanopharmaceuticals targeted to human epithelial barriersLehr, C.-M. / Hittinger, M. / Loretz, B. / Murgia, X. / Carvalho-Wodarz, C. / Schneider-Daum, N. et al. | 2018
- S26
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Single cell imaging for quantitative systems toxicology of hepatoxicityvan de Water, B. / Leist, M. / Beltman, J. / Kamp, H. / Hengstler, J. et al. | 2018
- S27
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N3RvousSystem: A 3R systems biology strategy for human neurotoxicity hazard, risk and safety assessmentWesterink, R.H.S. / Albrecht, C. / Sofranko, A. / Stahlmecke, B. / Breitenstein, D. / Pijnenburg, D. / Bokkers, B. / Schins, R.P.F. / Heusinkveld, H.J. et al. | 2018
- S30
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Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and humanPognan, F. et al. | 2018
- S31
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Respirometric screening and characterization of mitochondrial toxicities induced by ToxCast chemicalsSimmons, S.O. et al. | 2018
- S34
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Rethinking immunotherapy for neurodegenerative diseasesTjalkens, R. et al. | 2018
- S35
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Carbon load in airway macrophages as a biomarker of chronic exposure to air pollutionNemery, B. et al. | 2018
- S36
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Application of adverse outcome pathways (AOPs) in ecotoxicology – A multi-taxon AOP network to reduce animal testingVergauwen, L. et al. | 2018
- S37
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Harmonised risk assessment for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals: a food and feed safety perspectiveDorne, J.-L.C.M. / Benford, D. / Ragas, A. / Posthuma, L. / Kass, G.E. / Manini, P. / Dujardin, B. / Benfenati, E. / Hardy, A. / Testai, E. et al. | 2018
- S38
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What can we do better in bringing safe medicines to children - an industry perspectiveSchmitt, G. et al. | 2018
- S40
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AOP-based ontologies for developmental toxicityKnudsen, T.B. et al. | 2018
- S41
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Impact of oral exposure to nanomaterials for consumersBouwmeester, H. et al. | 2018
- S43
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3Rs Favourable CNS evaluation: Integration of safety pharmacology endpoints in toxicology studiesRedfern, W.S. et al. | 2018
- S44
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Role of the innate immunity in drug-induced hepatotoxicityJaeschke, H. et al. | 2018
- S45
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Neutrophil-monocyte interplay in drug-induced liver injuryPieters, R. / Bol-Schoenmakers, M. / Weaver, R. / Smit, J. / Giustarini, G. et al. | 2018
- S47
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Building an AOP based prenatal developmental toxicity ontologyPiersma, A.H. et al. | 2018
- S48
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Developing solutions to detect and avoid cardiovascular toxicity in the clinicValentin, J.-P. / Delaunois, A. et al. | 2018
- S51
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How effectively toxicology saves consumers?Goumenou, M. et al. | 2018
- S52
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Importance of fetal thyroid hormone signaling to brain development: a window of vulnerability for endocrine disruptionDemeneix, B.A. / Fini, J.-B. / Leemans, M. / Mughal, B. / LeMevel, S. / Spirhanslova, P. et al. | 2018
- S53
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From cohorts to organoids: endocrine disruption in human neurodevelopmental modelsCaporale, N. / Germain, P. / Cheroni, C. / Chorev, N. Even / Tobon, A. Lopez / Trattaro, S. / D'Agostino, G. / Bressan, R.B. / Pollard, S. / Testa, G. et al. | 2018
- S57
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Steatotic effects of propiconazole and tebuconazole in human liver cells are PXR-mediatedKnebel, C. / Nguyen, D.H.D. / Lampen, A. / Braeuning, A. / Marx-Stoelting, P. et al. | 2018
- S59
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Nrf2 regulates the skin innate immune response to chemical sensitizersHelou, D.G. / Noel, B. / Gaudin, F. / Groux, H. / Pallardy, M. / Chollet-Martin, S. / Kerdine-Römer, S. et al. | 2018
- S61
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Troglitazone and Rosiglitazone profiles in Tox21/Toxcast: Verifying results with toxicology data from published in vivo data and human pharmacovigilance data using an evidence-based approachDirven, H. / Vist, G. / Sayed, A. / Bandhakavi, S. / Branik, M. / Peace, N. / Tsaioun, K. et al. | 2018
- S62
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Development and validation of computational models for predicting oxidative stress responses using comprehensive series of drug-like compoundsPastor, M. / Westen, G.J.P. / Gómez-Tamayo, J.C. / Lenselink, B.E. / Lam, C.-C. / Water, B. / Norinder, U. / Manganelli, S. / Gadaleta, D. / Roncaglioni, A. et al. | 2018
- S63
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In utero exposure to cigarette smoke and NAFLD pathways: Sex and age specific effects in the human fetusTalia, C. / Filis, P. / Soffientini, U. / Lucendo-Villarin, B. / Douglas, A. / Hay, D. / Shaw, S. / Iredale, J.P. / Swortwood, M.J. / Huestis, M.A. et al. | 2018
- S65
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Evaluation of 3D skin model-based assays using difficult to test substances: an EPAA multi-sector projectIrizar, A. / Mehling, A. / Adriaens, E. / Casati, S. / Hubesch, B. / Klaric, M. / Manou, I. / Mueller, B. / Roggen, E. / van Vliet, E. et al. | 2018
- S66
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A novel in-vitro human skin explant test to predict adverse immune reactions to biologics and aggregated monoclonal antibodiesBibby, L. / Ribeiro, A. / Ahmed, S. / Dickinson, A.M. et al. | 2018
- S67
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Lung-on-a-Chip: The interplay of primary human epithelial and endothelial cells improves the alveolar barrier functionStucki, A.O. / Raggi, G. / Sigrist, S. / Zamprogno, P. / Schneider-Daum, N. / Lehr, C.-M. / Huwer, H. / Stucki, J.D. / Hobi, N. / Guenat, O.T. et al. | 2018
- S70
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Weight of evidence skin sensitization safety assessment using the bayesian net integrated testing strategyKern, P.S. / Ryan, C.A. / Deconinck, E. / Jaworska, J. / Dameron, G. et al. | 2018
- S71
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Developmental toxicity assessment of thalidomide and its derivatives lenalidomide and pomalidomide in zebrafish embryosGonzalez, I. / Ipiñazar, M. / Altuna, A. / Quevedo, C. et al. | 2018
- S73
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Proteomics and AllerCatPro analysis for the identification of low allergenic proteinsKrutz, N.L. / Winget, J. / Ryan, C.A. / Wimalasena, R. / Maurer-Stroh, S. / Dearman, R. / Kimber, I. / Gerberick, G.F. et al. | 2018
- S75
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Human In Vitro models for respiratory toxicology: evaluation of goblet cell hyperplasia, mucus production, and ciliary beating assaysGilbert, B. / Hill, E. / Aragon, M. / Frentzel, S. / Hoeng, J. / Ito, S. / Ishikawa, S. / Budde, J. / Maione, A.G. / Hayden, P. et al. | 2018
- S76
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Assessment of pre/prohaptens and surfactants using the SENS-IS assay, to measure skin sensitization potencyCottrez, F. / Boitel, E. / Groux, H. et al. | 2018
- S78
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Addressing the exceptions of the limitation for highly volatile substances in the Short Time Exposure (STE) test method and the predictive performance for assessing eye irritation potentialAbo, T. / Yuki, T. / Xu, R. / Araki, D. / Takahashi, Y. / Sakaguchi, H. / Itagaki, H. et al. | 2018
- S79
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Use of tests on Hydra attenuata and Brachydanio rerio for teratogenic testsSornat, R.E. / Krakowian, D. / Napora-Rutkowska, M. / Faron, J. / Gruszka, K. / Wolany, M. / Mrzyk, I. / Kropidlo, A. / Paleczny, M. / Rzodeczko, H. et al. | 2018
- S81
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Developmental expression of genes involved in the metabolism and transport of xenobiotics in the zebrafish from the embryonic until the juvenile stageBars, C.C.C. / Verbueken, E. / Periz-Stanaćev, J. / Vergauwen, L. / Michiels, E. / Stinckens, E. / Gabriëls, I. / Knapen, D. / Van Ginneken, C. / Van Cruchten, S.J. et al. | 2018
- S86
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Effects of rapamycin on in vivo and ex vivo cell-mediated immune responses in cynomolgus monkeysAncian, P. / Grosdidier, E. / Decheix-Nguyen, A. / Sarlang, S. / Descotes, J. et al. | 2018
- S88
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Expression of line-1 retrotransposon induced by environmental pollutants in breast cancer cellsMiret, N. / Zappia, D. / Zárate, L. / Pontillo, C. / Chiappini, F.A. / Lasagna, M. / Cocca, C. / Monczor, F. / Randi, A.S. et al. | 2018
- S90
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Chances for reducing rodent carcinogenicity testing of human pharmaceuticalsVan der Laan, J.W. / Bode, G. / Pasanen, M. et al. | 2018
- S91
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Oncogenic biomarkers in the safety assessment of novel food sourcesShestakova, S.I. et al. | 2018
- S93
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Prospective follow-up study on battery ingestion in children in the NetherlandsNugteren, J.J. / Hunault, C.C. / van Riel, A.J.H.P. / de Vries, I. et al. | 2018
- S94
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Metabolic dysfunction and obesogenic effects in individuals with the acute and chronic intoxication of pesticidesBubalo, N. / Balan, G. / Zhminko, P. / Bubalo, V. / Usenko, T. / Rashkivska, I. et al. | 2018
- S99
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Computational approaches for predicting Molecular Initiating EventsAllen, T.E.H. / Goodman, J.M. / Grayson, M.N. / Gutsell, S. / Russell, P.J. et al. | 2018
- S100
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Meta-analysis for genotoxicity prediction using data from multiple human in vitro cell modelsBayjanov, J.R. / Kleinjans, J.C. / Jennen, D.G.J. et al. | 2018
- S102
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In silico approaches in the selection of a series of aroylhydrazones bearing melatonin moiety for neuropharmacological testingGateva, P. / Ramanathan, K. / Shanthi, V. / Nivya, J. / Kamenova, K. / Angelova, V. / Tchekalarova, J. et al. | 2018
- S104
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ToxGPS, a solution guiding read-across workflow based on chemoinformatics and safety assessmentYang, C. / Bienfait, B. / Cronin, M.T.D. / Fioravanzo, E. / Gatnik, M. / Kleinoeder, T. / Park, J. / Liu, J. / Magdziarz, T. / Marusczyk, J. et al. | 2018
- S106
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Development of a high content imaging assay to assess drug induced lysosome perturbationBaines, I.A. / Davis, L.J. / Lennon, M.G. / Taylor, C.G. / Dare, T.O. / Bright, N.A. / Luzio, J.P. / Parry, J.D. / Gresham, S.L. / Dear, G.J. et al. | 2018
- S107
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Ursodeoxycholic acid modulates intracellular redox state and sensitizes colon cancer cells to the cytotoxicity induced by epigenetic agent vorinostatPavlovic, N. / Stankov, K. / Stanimirov, B. / Djanic, M. / Bogdanovic, G. / Golocorbin-Kon, S. / Mikov, M. et al. | 2018
- S109
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Fluoxetine affects midbrain neuronal specification and neurogenesis in vitroLupu, D. / Varshney, M. / Nalvarte, I. / Insunza, J. / Loghin, F. / Rüegg, J. et al. | 2018
- S111
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Development of high-throughput liver-on-a-chip for drug toxicity screeningWilschut, K. / Annida, R.J. / Wang, Z. / Ng, C. / Shevchenko, V. / Chesne, C. / Joore, J. et al. | 2018
- S114
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Development of highly sensitive and specific in vitro renal solute carrier (SLC) uptake cell models using normal human adult renal proximal tubule epithelial cells for drug transporter interaction studiesMenth, R. / Zou, C. / Romero, L. / Turner, E. / Huang, K. / Gibson, A. / McWilliams-Koeppen, P. / Chase, B. et al. | 2018
- S116
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Novel differentiation of human induced pluripotent stem cell-drived intestinal organoids (HiOs) for evaluation of intestinal fibrosisOnozato, D. / Akagawa, T. / Kida, Y. / Ogawa, I. / Hashita, T. / Iwao, T. / Matsunaga, T. et al. | 2018
- S118
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Non in vivo skin sensitization strategy under REACh in practice: Hurdles that need attention to minimize the need for in vivo testingPelgrom, S. / Barentsen, H. / Jonis, S. / Westerink, W. / Rijk, J. / Paulussen, J. et al. | 2018
- S119
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Neural crest related gene transcripts could serve as future targets for biomarker selection in the cardiac embryonic stem cell testMennen, G. / Pennings, J. / Piersma, A.H. et al. | 2018
- S121
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Streptococcus pneumoniae inhibits Pseudomonas aeruginosa growth on nasal human epithelium in vitroConstant, S. / Alouani, P. / Huang, S. / Bertinetti, C. / Verbeke, O. / Wiszniewski, L. / Caul-Futy, M. et al. | 2018
- S122
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Neurospheres for species-specific, medium-throughput analyses of developmental neurotoxicity (DNT) EvaluationFritsche, E. / Masjosthusmann, S. / Förster, N. / Baumann, J. / Bendt, F. / Dach, K. / Hübenthal, U. / Schmuck, M. / Temme, T. / Mosig, A. et al. | 2018
- S123
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Differentiation of hepatotoxic compounds by metabolomics in HepG2 cellsSperber, S. / Birk, B. / Haake, V. / Walk, T. / van Ravenzwaay, B. / Kamp, H. et al. | 2018
- S126
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Acute lung injury on-chip: building a disease predictive model that emulates alveolar biomechanicsRoldan, N. / Rapet, A. / Stucki, A.O. / Raggi, G. / Fytianos, K. / Geiser, T. / Hobi, N. / Guenat, O.T. et al. | 2018
- S127
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Rapid and accurate high-throughput in vitro prediction of nephrotoxicity in humans with ProxTox-HTSde Wilde, R. / Kovács, B. / Gliesche, D. / Zink, D. et al. | 2018
- S129
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Liver-chip identifies mitochondrial dysfunction, oxidative stress, and innate immune response as potential pathways of toxicity for the GPR40 agonist TAK-875Jang, K.-J. / Otieno, M. / Ronxhi, J. / Kodella, K. / Rubins, J. / Simic, D. / Singer, M. / Lim, H.-K. / Lam, W. / Chen, J. et al. | 2018
- S130
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Simultaneous measurement of contractility, electrophysiology and biomarker secretion to determine cardiotoxicity in hiPSC derived cardiomyocytesFouassier, A. / Braam, S. / Tessa, D.K. / Marijn, V. / Farbod, F. / Greg, L. et al. | 2018
- S131
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A realistic mixture of persistent organic pollutants (POPs) reveals possible synergism to inhibit the transactivation activities of the rat aryl hydrocarbon receptor (rAhR) in vitroDoan, Q.T. / Muller, M. / Berntsen, H.F. / Zimmer, K.E. / Verhaegen, S. / Ropstad, E. / Connolly, L. / Scippo, M.-L. et al. | 2018
- S133
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Assessment of the oxidative stress effects on the reproductive system of young male rats to n-butylparabenBru, E. Schreiber / Garcia, T. / Torrente, M. / Kumar, V. / Sharma, R.P. / Domingo, J.L. / Gómez, M.M. et al. | 2018
- S134
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Identification of endocrine active substances in medical devices within testing strategy according to ISO 10993-1Raemisch, A. / Mueller, A. / Deters, A. / Poth, A. et al. | 2018
- S135
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Investigation of possible effect of carnosic acid (CA) on combined exposure to bisphenol A (BPA) and diethyl hexyl phthalate (DEHP)Özdatlı, S. / Kalkan, R. / Hatimoğlu, M. / Kilic, U. / Aydın, A. et al. | 2018
- S137
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Prenatal phthalate exposure levels in the Flemish 3xG cohortDe Soomer, M. / Lambrechts, N. / Remy, S. / Govarts, E. / Morrens, B. / Hond, E. Den / Nelen, V. / De Decker, A. / Loots, I. / Schoeters, G. et al. | 2018
- S139
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Investigation of pyrrolizidine alkaloids – cytotoxicity tests using primary rat hepatocytes and HepG2 cells: Role of cytochrome P450 3AGao, L. / Rutz, L. / Merz, K.-H. / Schrenk, D. et al. | 2018
- S140
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P10-07 The safety assessment of proteins in food: where do we stand?Dumont, A. Fernandez / Paoletti, C. / Ruiz, J. Gomez / Ardizzone, M. / Lanzoni, A. et al. | 2018
- S141
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Health effects of red meat products containing phytochemicals and reduced levels of nitrite: the PHYTOME projectvan Breda, S.G. / de Kok, T.M. et al. | 2018
- S142
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Transcriptome responses in Caco-2 cells to micro- and nanoparticles in food-grade titanium dioxide (E171) and potential impact on colon cancer developmentBriede, J. / Proquin, H. / de Kok, T.M. / van Loveren, H. et al. | 2018
- S143
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A tool to integrate scientific risk assessment principles into the management and prioritization of chemical contaminants in raw materialsStroheker, T. / Scholz, G. / Mazzatorta, P. et al. | 2018
- S146
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Toxicity and metabolism of deoxynivalenol in human hepatoma (HepG2) cell lineRadko, L. / Tkaczyk, A. / Jedziniak, P. / Stypuła-Trębas, S. / Posyniak, A. et al. | 2018
- S147
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HPLC-FLD and LC-MS/MS determination of aflatoxin M1 from milk after biofixators usageIvešić, M. / Kuharić, Z. / Pavlek, Z. / Jakopović, Z. / Čanak, I. / Frece, J. / Markov, K. / Bošnir, J. et al. | 2018
- S148
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Genotoxicity of molybdenum(III) and nickel(II) and interactions between these microelementsTerpilowska, S. / Siwicki, A.K. et al. | 2018
- S150
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Investigation of the potential non-genotoxic mode of action for 1, 2-Dichloroethane (DCE)-induced mammary tumors in female ratsBoverhof, D.R. / Hotchkiss, J.A. / LeBaron, M.J. / Segal, L.M. / Howick, C. et al. | 2018
- S151
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Assessment of the sensitivity of the Ames Assay to pick up true mutagens at concentrations lower than the maximum OECD TG471 guideline doseHolland, D. / Pfuhler, S. et al. | 2018
- S153
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Combined application of comprehensive DNA analysis for DNA modification and reporter gene mutation assay to investigation of the mechanisms underlying hepatocarcinogenicity of elemicinIshii, Y. / Shi, L. / Takasu, S. / Kijima, A. / Ogawa, K. / Umemura, T. et al. | 2018
- S154
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Genetic toxicological comparison of Extract of Acer tegmentosumCho, E. / Kim, Y. / Yoon, J. / Kim, S. / Kim, D. / Kang, B. et al. | 2018
- S155
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Evaluation of Inhaled Low Dose Formaldehyde Induced DNA Damage by Liquid Chromatography-Tandem Mass SpectrometryLeng, J. / Liu, C.-W. / Hartwell, H.J. / Yu, R. / Lai, Y. / Lu, K. / Leibold, E. / Swenberg, J.A. et al. | 2018
- S157
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Compilation of historical negative and positive control group data of CHO-HPRT assay as per OECD guidelinesMishra, K.K. / Vashi, K.D. / Barad, I.M. / Nagane, R.M. et al. | 2018
- S159
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Genes associated with Parkinson's disease respond to increasing polychlorinated biphenyl levels in the blood of healthy femalesBohler, S. / Espín-Pérez, A. / Gebel, S. / Bergdahl, I. / Palli, D. / Rantakokko, P. / Kiviranta, H. / Kyrtopoulos, S. / Balling, R. / Kleinjans, J.C.S. et al. | 2018
- S160
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An integrated understanding of metabolic processes relevant to mammalian and environmental toxicology in the context of REACHMehmood, Z. / Fisk, P. / Wildey, R. et al. | 2018
- S161
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The use of a THP-1/3D reconstructed human epidermis (RHE) coculture system to assess the sensitizing potential of chemicalsSchellenberger, M.T. / Bock, U. / Hennen, J. / Groeber-Becker, F. / Walles, H. / Blömeke, B. et al. | 2018
- S162
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Development of an in chemico/in vitro testing strategy to assess the respiratory toxicity of inhalable substances from chemical-, consumer goods- and pharmaceutical industryBlömeke, B. / Hennen, J. / Bock, U. / Hittinger, M. / Groß, H. / Lehr, C.-M. / Birk, B. / Ma-Hock, L. / Landsiedel, R. / Kirsch, T. et al. | 2018
- S164
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Spatiotemporal variability of N-nitrosamines exposure in drinking water of a high incidence area of esophageal cancerYin, L. / Zhao, C. / Feng, Y. / Miao, Y. / Liu, R. / Pu, Y. et al. | 2018
- S165
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Chemical analysis of metallic trace elements of toxicological concern in Lebanese pita and risk characterization for the consumersLebbos, N. / Bou-Maroun, E. / Daou, C. / Ouaini, R. / Chebib, H. / Keller, C. / Afram, M. / Curmi, P. / Chagnon, M.-C. et al. | 2018
- S166
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Outdoor and indoor air pollution exposure: A cross-sectional study in Dakar city (Senegal)Ndong, A. / Verdin, A. / Thomas, J. / Cazier, F. / Cabral, M. / Garat, A. / Allorge, D. / Garcon, G. / Loguidice, J.-M. / Diouf, A. et al. | 2018
- S167
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Derivation of a point of departure for alkyl-substituted urea compounds using a category-based read-across approachLampe, B.J. et al. | 2018
- S168
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Life-course exposure and physical activity impact on genomic biomarkers of a group of older adultsTeixeira-Gomes, A. / Lage, B. / Silva, S. / Esteves, F. / Carvalho, J. / Valdiglesias, V. / Teixeira, J.P. / Costa, S. et al. | 2018
- S169
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Degradation of cyclophosphamide using plasma activated water and UV/H2O2 for the abatement of persistent pharmaceuticals in wastewaterGraumans, M.H.F. / Hoeben, W.F. / Russel, F.G. / Leenders, P.H. / Scheepers, P.T.J. et al. | 2018
- S171
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Human exposure to disinfection by-products in indoor swimming pools - looking at the genotoxic effectsEsteves, F.C. / Amaro, A. / Silva, S. / Costa, C. / Costa, S. / Teixeira, J.P. et al. | 2018
- S172
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Ad hoc risk assessments by Front Office Food and Product SafetyJeurissen, S. / de Jonge, R. / Schuur, G. / Keizers, P. / Hoogenboom, R. et al. | 2018
- S173
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Exploring the presence of ESBL-producing bacteria in different aquatic ecosystems in EnglandAnjum, U. / Reid, R. / Hoosen, H. / Lobo-Bedmar, M.C. / Fernández, A. Peña et al. | 2018
- S174
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Effect of the herbicide paraquat in larval phase of the BullfrogEstrada, A.C. Razo / Jiménez-García, B.G. / Pérez, N.-A. Romero / Guzmán-Ibarra, R.D.C. et al. | 2018
- S175
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Environmental risk assessment and spatiotemporal variability of atmospheric volatile organic compounds and nitrogen dioxide using passive sampler in Meknes City (Morocco)Ghazi, I. El / Berni, I. / Menouni, A. / Kestemont, M.-P. / Amane, M. / Jaafari, S. El et al. | 2018
- S176
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Behavioral effects changes in rats exposed to real-life chemical mixture at doses around toxicological reference valuesDocea, A.O. / Calina, D. / Gofita, E. / Arsene, A.L. / Zlatian, O. / Nicolae, A. Crenguţa / Drăgoi, C.M. / Nosyrev, A. / Izotov, B. / Buga, A.M. et al. | 2018
- S177
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Primary risk assessment done after detection of fipronil in eggs in BelgiumFierens, S. / Lernout, T. / Vleminckx, C. et al. | 2018
- S179
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Evaluation of an integrated strategy for skin allergy risk assessment using six ingredients and two cosmetic product typesVandenbossche, E. / Baltazar, M. / Butcher, J. / Cubberley, R. / Gilmour, N. / MacKay, C. / Pendlington, R. / Reynolds, J. / Maxwell, G. et al. | 2018
- S181
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Immunoprotective effects of selenium on hepatorenal toxicity induced by scorpion venomMegdad-Lamraoui, A. / Adi-Bessalem, S. / Laraba-Djebari, F. et al. | 2018
- S184
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Reduced risk of allergy induction for hairdressers? An occupational risk assessment for the new oxidative hair dye 2-methoxymethyl-p-phenylenediamineGoebel, C. / Gargano, E.M. / Gaspari, A.A. / Blömeke, B. et al. | 2018
- S186
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Characterization of cytochrome p450 induction by the type ii pyrethroid lambda-cyhalothrinAnadón, A. / Ares, I. / Rodríguez, J.-L. / Martínez, M. / Lopez-Torres, B. / Roura-Martínez, D. / Martínez-Larrañaga, M.-R. / Martínez, M.-A. et al. | 2018
- S187
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In vivo comparison between two nephrotoxic agents, sodium fluoride and uranyl nitrate: phenotypic aspects and molecular mechanisms involvedBontemps, A. / Conquet, L. / Elie, C. / Magneron, V. / Gloaguen, C. / Kereselidze, D. / Tack, K. / Barbier, O. / Guéguen, Y. et al. | 2018
- S189
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Respiratory hazard of Li-ion battery components: elective toxicity of lithium cobalt oxide (LiCoO2) particles via IL-1β and HIF-1αSironval, V. / Reylandt, L. / Ibouraadaten, S. / Palmai-Pallag, M. / Yakoub, Y. / Tomatis, M. / Ucakar, B. / Vanbever, R. / Marbaix, E. / Lison, D. et al. | 2018
- S190
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Revisiting the paradigm of silica pathogenicity: silanols, not crystallinity, as key determinantPavan, C. / Turci, F. / Tomatis, M. / Leinardi, R. / Pastero, L. / Fabbiani, M. / Martra, G. / Fubini, B. / Lison, D. et al. | 2018
- S191
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Mechanism of chronic ethanol consumption-induced oxidative stress in mice renal cortex: involvement of iNOSSilva, C.B.P. / Gonzaga, N.A. / Ceron, C.S. / Santos, J.D. / Castro, M.M. / Tirapelli, C.R. et al. | 2018
- S192
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The synthetic psychostimulant 4-fluoromethamphetamine induces in vitro hepatotoxic effects, via CYP2E1 metabolismBravo, R.R.D.S. / Moreira, P. / Carvalho, F. / Bastos, M.D.L. / Carmo, H. / Silva, D. Dias da et al. | 2018
- S193
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Unravelling essential key events in mitochondrial adverse outcome pathwaysvan der Stel, W. / Darici, S. / van de Water, B. / Danen, E. et al. | 2018
- S195
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The mechanism for potentiation of the combined effects of 2, 4-D and methylmercury in warm-blooded organismsRakitskii, V. / Sinitskaya, T. et al. | 2018
- S196
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A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in ratsSingh, P. / Strupp, C. / Bomann, W.H. / Spézia, F. / Gervais, F. / Forster, R. / Richert, L. et al. | 2018
- S197
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Hepatic and thyroid effects of phenobarbital in the minipigBoje Nielsen, J. / Decorde, J. / Erratico, C.-A. / Parmentier, C. / Untrau, M. / Bansard, C. / Ancian, P. / Fonsi, M. / Richert, L. / Forster, R. et al. | 2018
- S198
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Multiple targets/molecular initiating events, for OP neurotoxicity may be related with interactions of cholinesterase and phenylvalerate activities in chicken, the model of delayed neurotoxicityEstévez, J. / Benavent, M. / Selva, V. / Mangas, I. / del Río, E. / Sogorb, M.A. / Vilanova-Gisbert, E. et al. | 2018
- S199
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Sterigmatocystin induces oxidative stress in male Wistar ratsRašić, D. / Želježić, D. / Micek, V. / Kifer, D. / Jakšić, D. / Peraica, M. / Kopjar, N. / Klarić, M. Šegvić et al. | 2018
- S200
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Combined assays on isolated heart mitochondria and Cor.4U hiPS-derived cardiomyocytes to predict drug-induced cardiotoxicityMartel, C. / Pertuiset, C. / Aubry, B. / Porceddu, M. / Buron, N. / Kettenhofen, R. / Fouassier, A. / Borgne-Sanchez, A. et al. | 2018
- S203
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Carbon nanotubes influence surface properties of the phospholipid membraneKondej, D. / Sosnowski, T.R. et al. | 2018
- S204
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Behavioral alterations in the short and long term after chronic exposure of silver nanoparticles to young ratsOrzelska-Gorka, J. / Struzynska, L. / Talarek, S. / Kedzierska, E. / Biala, G. et al. | 2018
- S209
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Iron oxide nanoparticle toxicity on human cell lines, aquatic and soil organisms and interactions with metal pollutantsCabellos, J. / González-Andrés, V. / Diez-Ortiz, M. / Janer, G. et al. | 2018
- S210
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Hazard assessment for a Ti-based nano-additived material: from core-shell production to final partVerstraelen, S. / Van Rompay, A. / Jacobs, A. / Hollanders, K. / Boonen, F. / Geukens, G. / Frijns, E. / Geerts, L. / Weltens, R. et al. | 2018
- S211
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Single-walled and multi-walled carbon nanotubes induce epigenetic alterations in association with the nuclear deposition in 16 HBE cellsGhosh, M. / Öner, D. / Bové, H. / Moisse, M. / Boeckx, B. / Duca, R.C. / Vanoirbeek, J.A.J. / Ameloot, M. / Bekaert, B. / Lambrechts, D. et al. | 2018
- S212
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Insights into the role of the physicochemical properties in the toxicity of SiO2 nanoparticles in rat alveolar epithelial RLE-6TN cellsBrandão, M.F.P. / Bessa, M.J. / Costa, C. / Fraga, S. / Haase, A. / Teixeira, J.P. et al. | 2018
- S215
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Data-driven identification of interspecies pathway perturbations in vivo and in vitro: the case of Nrf2Souza, T.M. / Kleinjans, J.C.S. / Jennen, D.G.J. et al. | 2018
- S217
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Enabling high throughput transcriptomics (HTTr) for mechanistic toxicology by tuning dynamic rangeVan Steenhouse, H. / Yeakley, J. / Shepard, P. / McComb, J. / Seligmann, B. et al. | 2018
- S218
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FDA SEND process streamlining and implementation – CT-compatible simulated studyAnzai, T. / Aerni, R. / Wasko, M. / Mura, F. / Horikawa, S.-I. / Sato, S.-I. / Murase, Y. / Hatakeyama, H. et al. | 2018
- S219
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Application of a new biochip array platform to the simultaneous screening of drugs of abuse in urine and oral fluid in under 20minAnderson, V. / Cardwell, S. / Doone, D. / Dicks, J. / Speers, A. / Darragh, J. / Vance, P. / Dyttus, O. / Rodríguez, M.L. / Benchikh, M.E. et al. | 2018
- S221
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Follow-up on worthiness of LICl use in the rats' dietSadykova, E.O. / Shestakova, S.I. / Timonin, A.N. / Trebukh, M.D. et al. | 2018
- S222
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Reviewing the use of two species in toxicology studies supporting drug developmentPrior, H. / Gellatly, N. / Sewell, F. / Kimber, I. et al. | 2018
- S223
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Use of recovery animals for human safety assessment across the pharmaceutical development packageSewell, F. / Gellatly, N. / Prior, H. et al. | 2018
- S224
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Rotational thromboelastometry for ex vivo assessment of drug effects on platelet functionAuthier, S. / Negro, F. Silva / Saint-Jean, C. / Li, C. / Forster, R. / Foulon, O. et al. | 2018
- S225
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DNA microarray analysis on characteristics of hepatocyte-like cells derived from human iPS cells for the application to the cell based drug safety testsIshida, S. / Horiuchi, S. / kuroda, Y. / Fujii, R. / Kim, S.-R. / Kanda, Y. et al. | 2018
- S226
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Guidance for synthesising epidemiology evidence for the UK Committee on Toxicity (COT) and on Carcinogenicity (COC) of chemicals in foods, consumer products and the environmentGott, D. / Hansell, A. / Potter, C. et al. | 2018
- S227
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Introducing WikiPathways to link molecular pathways to adverse outcome pathways to support regulatory risk assessmentMartens, M. / Willighagen, E. / Nymark, P. / Grafström, R. / Burgoon, L.D. / Aladjov, H.T. / Andón, F. Torres / Evelo, C.T. et al. | 2018
- S228
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Antibody-drug conjugates: strategies, experiences and challenges from the non-clinical development to clinical development in cancer treatment in FranceBurbank, M.G. / Menoret, C. / Lopes, S. / Gazin, V. / Boudali, L. et al. | 2018
- S229
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Anticancer effect of arsenic compounds on apoptosis in oral cavity cancer cellsHuang, B.-M. et al. | 2018
- S231
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New approach for assessment of Wistar Hannover male rats reproductive toxicityKolianchuk, Y. / Prodanchuk, M. / Nedopytanska, N. / Rashkivska, I. / Bubalo, V. / Usenko, T. et al. | 2018
- S232
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Coenzyme Q10 supplementation rescues infertility and reproductive outcomes following exposure to the endocrine disruptor bisphenol A in Caenorhabditis elegansHornos Carneiro, M.F. / Shin, N. / Colaiacovo, M.P. et al. | 2018
- S233
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Prenatal administration of SMe1EC2 changed anxiety- and depression-like behavior with changes in the brain oxytocin expression of adult offspringStefanik, P. / Olexova, L. / Dzirbikova, Z. / Ujhazy, E. / Mach, M. et al. | 2018
- S235
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Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneysCurcic, M. / Đorđević, A. Buha / Milovanović, V. / Janković, S. / Vučinić, S. / Antonijević, E. / Đukić-Ćosić, D. / Bulat, Z. / Matović, V. / Antonijević, B. et al. | 2018
- S236
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Toxicity of DEP and metal oxide nanoparticles mixtures in human lung cellsZerboni, A. / Mantecca, P. et al. | 2018
- S237
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A comparative high-content screening-based assessment of e-cigarette liquids in primary bronchial epithelial cellsMarescotti, D. / Taylor, M. / Gonzalez-Suarez, I. / Acali, S. / Walker, P. / Belcastro, V. / Martin, F. / Frentzel, S. / Thorne, D. / Peitsch, M.C. et al. | 2018
- S238
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Quercetin ameliorates cadmium chloride-induced hepatotoxicity in Wistar ratsEgbung, G.E. / Nna, V.U. / Atangwho, I.J. / Obi-Abang, M. et al. | 2018
- S239
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Attenuation of livery injury with hypothermia in acute hepatotoxicityTan, Y.L. / Ho, H.K. et al. | 2018
- S240
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Effects on cigarette smoke extract on cell proliferation and apoptosis in mouse embryonic stem cells via reactive oxygen species-induced endoplasmic reticulum stress signaling pathwaysKim, C.-W. / Go, R.-E. / Choi, K.-C. et al. | 2018
- S242
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The effects of dioxin action on hr-deficient epidermal keratinocytes are associated with changes in expression of AhR-regulated genes both in vitro and in hairless mouse skin in vivoRudyak, S.G. / Shinin, V.V. / Usakin, L.A. / Belushkina, N.N. / Paltsev, M.A. / Panteleyev, A.A. et al. | 2018
- S243
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The interaction between the guanidine polymers of disinfectants and cytoplasmic organellesYoo, S.H. / Jeong, M.H. / Jang, E.H. / Jung, Y.J. / Chung, K.H. et al. | 2018
- S245
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Subchronic toxicity of Al2O3, TiO2 and SiO2 nanoparticles in different combinations for rats and its attenuation with a complex of innocuous bioprotectorsKlinova, S.V. / Minigalieva, I.A. / Privalova, L.I. / Panov, V.G. / Makeev, O.G. / Valamina, I.E. / Shishkina, E.V. et al. | 2018
- S246
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Incorporation of toxicodynamic feedback in a physiologically-based toxicokinetic model of acetaminophen overdoseReddyhoff, D. / Fisher, C.P. / Gardner, I. et al. | 2018
- S249
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New approaches for parameterization and evaluation of PBK models using human in silico, in vitro, biomonitoring and volunteer dataBessems, J. / Schoeters, G. / Santonen, T. et al. | 2018
- S250
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An inter-species comparison approach for triclopyr, utilizing in silico, in vitro and in vivo toxicokinetic properties, for risk assessment purposeCorvaro, M. / Bartels, M. et al. | 2018
- S251
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High-throughput and non-depletive quantification of chemicals in a 3D liver microtissue in vitro assayTeixeira, A. / Lee, M.-Y. / Nicol, B. et al. | 2018
- S252
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Development of a novel in vitro aerosol exposure system: The Independent Holistic Air-Liquid aerosol exposure system (InHALES)Steiner, S. / Herve, P. / Majeed, S. / Pak, C. / Frentzel, S. / Hoeng, J. et al. | 2018
- S254
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Treatment of impaired wounds – Understanding the therapeutic mechanisms of umbilical cord-derived mesenchymal stem cellsCamões, S.P. / de la Fuente, A. / Carvalho, F. / Abal, M. / Santos, J.M. / Miranda, J.P. et al. | 2018
- S255
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Interplay of four genetic high risk variants for urinary bladder cancerSelinski, S. / Ickstadt, K. / Gerullis, H. / Otto, T. / Roth, E. / Volkert, F. / Ovsiannikov, D. / Moormann, O. / Banfi, G. / Nyirady, P. et al. | 2018
- S256
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A simplified numerical scoring system to quantify skin and eye irritation/corrosionPerea, M. / Charmeau-Genevois, C. / Sahigara, F. / Thomas, P. et al. | 2018
- S257
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Microextraction by Packed Sorbent (MEPS) for the determination of Polybrominated Diphenyl Ether (PBDE) in eggs by Gas Chromatography-Mass Spectrometry (GC-MS)Souza, M.C.O. / Rocha, B.A. / Souza, J.M.O. / Barbosa Júnior, F. et al. | 2018
- S258
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TOX-OER MOOC: The liver as target organRocha-Pereira, C. / Soares, J. / Casanova, A.G. / Carmo, H. / Carvalho, F. / Bastos, M.D.L. / Remião, F. et al. | 2018
- S263
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Determination of proinflammatory cytokines level and NF-κB activation level in the human lung cells line stimulated with essential oils for a vehicle ventilation system applicationJanicka, A. / Molska, J. / Zawiślak, M. / Czarny, A. / Zaczyńska, E. et al. | 2018
- S265
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Alginate microencapsulated capsaicin suppresses ROS production and sustains human dermal fibroblasts cells viabilityDragomir, S. / Hudita, A. / Galateanu, B. / Costache, M. / Ion, R.M. / Ginghina, O. / Stan, M. / Baconi, D.L. / Negrei, C. et al. | 2018
- S269
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Co-exposure to cocaine and ethanol induces oxidative impairment in H9c2 cardiomyocytesMartins, M.J. / Bravo, R.R.D.S. / Carmo, H. / Carvalho, F. / Bastos, M.D.L. / Dinis-Oliveira, R.J. / Dias da Silva, D. et al. | 2018
- S270
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A Single Intraventricular dose Toxicity Study of K-6187, mesenchymal stem cells, in Neonatal Sprague-Dawley RatsJeong, J.-S. / Park, D.-Y. / Koh, E.-M. / Chang, Y.-S. / Ahn, S.Y. / Jeong, E.J. et al. | 2018
- S271
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Biomonitoring of 18 trace elements in the urine of workers from a smelting industry in the state of São Paulo (Brazil)Freire, B.M. / Pedron, T. / Pedreira Filho, W.R. / Batista, B.L. et al. | 2018
- S272
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Classification of toxicological findings observed in repeated–dose toxicity tests by using statistical analysis with toxicity test databaseKitsunai, Y. / Takeshita, J.-I. / Watanabe, M. / Sasaki, T. / Hosaka, T. / Shizu, R. / Yoshinari, K. et al. | 2018
- vii
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EUROTOX Sponsors and Exhibitors| 2018
- XXVI
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Keyword Index| 2018
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Introduction to Social ToxicologyLiesivuori, J. / Tsatsakis, A.M. et al. | 2018
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The hidden face of monocytes in particle-induced fibrosis and mesotheliomaHuaux, F. et al. | 2018
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Pathway approaches in human toxicologyVinken, M. et al. | 2018
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New opportunities for psychoactive drugs in neuropsychopharmacological diseaseDuffy, P.A. et al. | 2018
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The bright and the dark sides of Nrf2 in wound repair and skin tumorigenesisWerner, S. et al. | 2018
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Towards realistic in vitro models for prediction of nanomaterials' immunotoxicity and impact on immune response developmentNelissen, I. et al. | 2018
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Mechanistic de-risking using 3D organoids: addressing human relevance of rat goblet cell expansionBertinetti-Lapatki, C. et al. | 2018
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How do the ADME properties of oligonucleotides influence their Therapeutic Index?Hood, S.R. et al. | 2018
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Evaluation of sex differences in diazepam and amphetamine conditioned place preference in Sprague Dawley ratsBreche, S. / Sablé, E. / Castagné, V. / Madar-Balakirski, N. / Kedar, H. / Froger-Colléaux, C. et al. | 2018
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An in-vitro investigation in rat L6 and mouse C2C12 cell lines into the skeletal muscle toxicity observed in the mouse of Trypanosoma Cruzi whole cell inhibitor compoundsGrimsditch, D. / Brunori, G. / Armitage, J. / Taylor, C. / Dare, T.O. / Lennon, M. / Jimenez-Navarro, E. / Valle, S. Gonzalez-Del / Gresham, S. / Lyon, J. et al. | 2018
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Electrophysiological evaluation of developmental neurotoxicity induced by the prenatal exposure to 1-bromopropaneFueta, Y. / Ishidao, T. / Yoshida, S. / Hori, H. / Yamasaki, D. / Kanda, Y. / Ueno, S. et al. | 2018
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An overview of popular (Q)SAR packages for regulatory purposes: an agrobusiness point of viewCalçada, B.E.S. / Dias, P.V.B. / Sousa, C.S.R. et al. | 2018
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Effects of double-walled carbon nanotubes on the pneumonia in respiratory syncytial virus-infected miceWatanabe, W. / Akashi, T. / Hirose, A. / Miyauchi, A. / Yoshida, H. / Kurokawa, M. et al. | 2018
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Dependence of developmental toxicity for polyaromatic hydrocarbons on aryl hydrocarbon receptor: Range-finding with benzo(a)pyreneKetelslegers, H. / North, C. / Van Otterdijk, F. / Adenuga, D. et al. | 2018
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Potential cytotoxic risk and chronical inflammation after exposure to graphene plateletsSvadlakova, T. / Malkova, A. / Kulich, P. / Masek, J. / Hubatka, F. / Knotigova, P. Turanek / Fiala, Z. / Borska, L. / Turanek, J. et al. | 2018
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Relative potency ranking of azoles altering cranio-facial morphogenesis in rat: an in vitro data modelling approachBattistoni, M. / Di Renzo, F. / Metruccio, F. / Moretto, A. / Menegola, E. et al. | 2018
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Implication of TGF-β in the immunosuppressive functions of mesotheliomagenic macrophagesKiyambu, H. / Hatem, C. Al / Palmai-Pallag, M. / Orsi, M. / Lison, D. / Huaux, F. et al. | 2018
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Microbiome composition of air samples from livestock farms and their effect on innate immune receptors and cellsLiu, D. / Mariman, R. / Gerlofs-Nijland, M.E. / Boere, J.F. / Folkerts, G. / Cassee, F.R. / Pinelli, E. et al. | 2018
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In vitro assessment of medical device extracts potential to produce skin sensitizationCottrez, F. / Pellevoisin, C. / Coleman, K. / Groux, H. et al. | 2018
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In vitro alternatives for assessing human safety of botanical mixturesMahony, C. / Vandermolen, K. / Otto-Bruc, A. / Naciff, J. / Kennedy, K. / Daston, G. et al. | 2018
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Chronic exposure to low concentration of di-(2-ethylhexyl) phthalate adversely affects aging indicators in Caenorhabditis elegansLiao, V. H.-C. / How, C.-M. / Yen, P.-L. et al. | 2018
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Refined assessment and perspectives on the cumulative risk resulting from the dietary exposure to pesticide residues in the Danish populationLarsson, M.O. / Laporte, F. / Bjerre, N. / Nielsen, V.S. / Cedergreen, N. et al. | 2018
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Are epigenetic modifications linked to BPS obesogen effect after perinatal exposure? Differential DNA methylation study in mouse liversBrulport, A. / Le Corre, L. / Vaiman, D. / Chagnon, M.-C. et al. | 2018
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Comparative inhalation toxicity testing using in vitro organotypic rat and human airway epithelial modelsHayden, P. / Jackson, G.R. / Vinall, J.L. / Storey, E. / Simpson, H. / Debatis, M. / Maione, A.G. / Roper, C. / Klausner, M. et al. | 2018
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An in vitro approach to e-cigarette toxicity testingSimms, L. / Czekala, L. / Stevenson, M. / Phillips, G. / Tilley, R. / Rudd, K. / Walele, T. et al. | 2018
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Impact and necessity of a kinase safety strategy for CNS IndicationsLemper, M. / Schramm, C. / Class, R. / Tilmant, K. / Neres, J. / Swinnen, D. / Geraerts, M. / De Wever, V. / Melas, I. / Camargo, M. et al. | 2018
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What is "overexpression"? Example: Glycoprotein (MUC 1) in Lung Cancer CarcinomaBode, G. / Paulitschke, M. / Joehrens, K. et al. | 2018
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Apoptosis activity on the vitamin and mineral deficiency model under CCL4 intoxicationShestakova, S.I. / Tyshko, N.V. et al. | 2018
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Watch out! pesticide exposure contributes to tumor angiogenesis in our breastsZárate, L. / Pontillo, C. / Español, A. / Miret, N. / Chiappini, F.A. / Cocca, C. / Álvarez, L. / Kleiman de Pisarev, D. / Sales, M.E. / Randi, A.S. et al. | 2018
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Effects of phenobarbital (PB) acute exposure on minipig liver gene expressionSilvano, J. / Ancian, P. / Bansard, C. / Nielsen, J. Boje / Singh, P. / Forster, R. et al. | 2018
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The effects of a plant-based antidiabetic supplement on the antioxidant capacity of serum and serum lipoproteins in diabetic ratsUngurianu, A. / Şeremet, O. / Grădinaru, D. / Ionescu-Tîrgoviște, C. / Dănciulescu-Miulescu, R. / Margină, D. et al. | 2018
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A new in vitro approach to verify the moisturizing activity of topical cosmetic productsRegola, E. / Vicini, R. / Buzzella, A. / Riva, F. / Mori, M. / Giorgetti, S. / Angelinetta, C. / Pastoris, O. et al. | 2018
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Creation of a stable and highly functional pluripotent stem cell derived hepatocyte model for drug metabolisation and toxicity screeningKumar, M. / Chesnais, F. / Boon, R. / Krebs, A. / Curtiss, C. / Toprakhisar, B. / Jacobs, F. / Schmidt, B. / Leist, M. / Verfaillie, C. et al. | 2018
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Toxicity assays using expanded liver cells promote the reduction of animal use in pre-clinical researchNagy, N. / Noerenberg, A. / Evenburg, T. / Johannssen, T. et al. | 2018
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The development of in vitro embryotoxicity testing using human iPS cellsAikawa, N. et al. | 2018
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A novel model of alphavirus-induced neurotoxicity for studying gene x environment interactionsBantle, C.M. / Roche, S.M. / Tjalkens, R.B. et al. | 2018
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MicroRNAs as signatures of structural cardiotoxicity in human induced pluripotent stem cell-derived cardiomyocytesGryshkova, V. / Palmer, J. / Smith, A. / Burrier, R. / Colwell, M. / Delaunois, A. / Costa, A. Nogueira da / Valentin, J.-P. et al. | 2018
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Case-study: Combining dietary and non-dietary pesticide exposure (hands-on training)Kennedy, M. et al. | 2018
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The effect of thiamine on oxidative stress and apoptosis in the liver of Japanese quails treated with chlorpyrifosMiladinović, D. Ćupić / Borozan, S. / Peković, S. / Dacić, S. / Đukić-Ćosić, D. / Ćupić, V. / Ivanović, S. et al. | 2018
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Exposure data for baby wipe productsNalin, A. / Herbin, C. et al. | 2018
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Polyethylemine coated silver nanoparticles induce human neutrophils' oxidative burst via NADPH oxidase, through the activation of PKCSoares, T. / Gónzalez-Gómez, M. / Rivas, J. / Freitas, P. / Carvalho, F. / Fernandes, E. / Freitas, M. et al. | 2018
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Reference reagents for a better harmonisation of Cytokine Release AssaysVessillier, S. et al. | 2018
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Evaluation of emerging biomarkers for major organ toxicities and disease statesEllinger-Ziegelbauer, H.C. / Hellmund, M. / Pavkovic, M. / Petzuch, B. / Raschke, M. / Riefke, B. / Slopianka, M. et al. | 2018
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Current challenges and opportunities in cardiac safety: a clinical perspectiveDarpo, B. et al. | 2018
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Industry perspective on the challenges and opportunities of the safety assessment of biologicalsSims, J. et al. | 2018
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European air pollution modelsHoek, G. / de Hoogh, K. et al. | 2018
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Ecological risk assessment of chemical mixturesRagas, A. et al. | 2018
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Physiology, pharmacology and toxicology of the Nrf2 pathwayCopple, I. et al. | 2018
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Antisense oligonucleotides – recent advances in preclinical safety assessmentFestag, M. et al. | 2018
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Data encounters at the in vitro-in vivo interface: building target to event hypothesisMunoz-Muriedas, J. et al. | 2018
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Future direction in immunotoxicology: immunosuppression as key playerHuaux, F. et al. | 2018
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PrefaceLison, Dominique / Wallace, Heather et al. | 2018
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Microorganisms reduce indoor air pollutionVerdonck, J. / Vanoirbeeck, J.A.J. / Poels, K. / Hoet, P.H.M. / Godderis, L. et al. | 2018
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Application of PBPK modelling of enterocyte exposure aids in vitro to in vivo translational risk assessment of μ-opioid-induced clinical constipationKavanagh, S. / Ribeiro, L. Rosenbrier / Noeske, T. / Sharma, P. et al. | 2018
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Natural antioxidants prevent contrast-induced nephropathy by enhancing nitric oxide synthesis in an animal modelFragkiadoulaki, I. / Mamoulakis, C. / Alegakis, A. / Tzatzarakis, M.N. / Karzi, V. / Stratidakis, A. / Renieri, E. / Vardavas, A. / Leon, G. / Tsitsimpikou, C. et al. | 2018
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Acute mixture toxicity of pesticide formulations and perspective of use in silico methods to complement risk assessment of plant protection productsKolesnyk, S. / Riabukha, O. / Prodanchuk, M. / Zhminko, P. / Vasetska, O. et al. | 2018
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Perinatal exposure to secondary organic aerosol influences neurobehavioral development and inflammatory markers in ratsWin-Shwe, T.-T. / Fujitani, Y. / Hirano, S. et al. | 2018
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Six-month systems toxicology inhalation/cessation study in ApoE−/− mice to investigate cardiovascular and respiratory exposure effects of two reduced risk products compared with conventional cigarettesSzostak, J.G. / Phillips, B. / Emmanuel, G. / Wong, E.T. / Titz, B. / Martin, F. / Vuillaume, G. / Leroy, P. / Buettner, A. / Vanscheeuwijck, P. et al. | 2018
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Possible role of n-hexane as endocrine disruptor in occupationally exposed women at reproductive ageRuiz-García, L. / Malacara-Hernández, J.M. / Figueroa-Vega, N. / Bartoloucci, G.B. / Carrieri, M. / Salamon, F. / Jiménez-Garza, O. et al. | 2018
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A new screening approach for the evaluation of retinoic acid receptor alpha (RARα) interaction of chemicalsBirk, B. / Demuth, P. / Roth, N. / Sessler, K. / Hüner, H.-A. / Verlohner, A. / Flick, B. / van Ravenzwaay, B. / Landsiedel, R. et al. | 2018
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Stereotactic surgeries and MRI-guided Convection-Enhanced Delivery (CED) into the striatum in cynomolgus macaquesLuft, J. / von Keutz, A. / Runge, F. / Voß, T. / Grote-Wessels, S. / Korte, S. et al. | 2018
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Percellome toxicogenomics project: newly designed repeated dose studyKanno, J. / Kitajima, S. / Ono, R. / Aisaki, K. et al. | 2018
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In vitro toxic effects of L-glutamic acid-g-p(HEMA) polymeric nanoparticleBakan, N.B. / Gülcemal, S. / Akgöl, S. / Hoet, P.H.M. / Yavaşoğlu, N.U. Karabay et al. | 2018
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A system-based comparative proteomics approach to investigate heavy metals mixtures toxicity mechanism relates to the neurodegeneration on hippocampal cell lineKumar, V. / Karri, V. / Edwin, M. / Coort, S.L. / Evelo, C.T. / Oliveira, E. / Schuhmacher, M. et al. | 2018
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1, 2-Diacetylbenzene with inflammatory related pathway associated neurotoxicityKim, M.-S. / Kang, S.-W. et al. | 2018
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Prenatal high fat diet alters DNA methylation and gene expression of metabolic genes in mouse offspringRouschop, S. / Karl, T. / Maas, L. / Risch, A. / Opperhuizen, A. / van Schooten, F.J. / Godschalk, R. et al. | 2018
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Up-regulation of bisphenol A-mediated BAFF expression in Raw264.7 murine macrophagesLee, S.H. / Yoon, S.S. / Moon, E.Y. et al. | 2018
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Evaluation of human health risks associated with toxic metals present in coastal ecosystem: a study on trophic level transfer of metals in Bay of Bengal, IndiaSatapathy, S. et al. | 2018
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Trends on PM2.5 research, 1997–2016: a bibliometric studyLiang, G. / Sui, J. / Wu, W. / Liu, T. / Xu, S. / Yin, L. / Pu, Y. et al. | 2018
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Subchronic inhaling toxicity study of diphenylcyanarsine in SD ratsLi, L. / Zhang, R. / Yin, Y. / Shi, T. / Wang, C. / Chen, X. / Xu, J. et al. | 2018
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UV-A and UV-B damage: the protective effect of Vitis vinifera L. extract on HaCaT cell lineLolli, F. et al. | 2018
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Genotoxic damage among Bolivian farmers exposed to a complex mixture of pesticidesBarron Cuenca, J.X. / Tirado, N. / Barral, J. / Almaraz, P. / Stenius, U. / Berglund, M. / Dreij, K. et al. | 2018
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Prospective hazards of fenvalerate in extensive pollution influence the apoptosis sensitivityCui, Z.-G. / Jin, Y.-J. / Sun, L. / Zakki, S.A. / Feng, Q. / Inadera, H. et al. | 2018
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Acute and sub-acute oral toxicity study of fermented platycodon extract in ratsHeo, J.-D. / Choi, J. / Kim, J. / Lee, S.-J. / Moon, Y.-G. / Kim, W.-S. / Tak, T.-K. / Lee, J.-H. / Hwang, K.-H. et al. | 2018
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Safety assessment of biotechnologically produced 2'-Fucosyllactose, a novel food additiveSalverda, J. / van Berlo, D. / Wallinga, A. / van Acker, F. / Delsing, D. et al. | 2018
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Safety evaluation of plants collected from the wild served as food in Danish restaurantsEgebjerg, M.M. / Olesen, P.T. / Eriksen, F.D. / Ravn-Haren, G. / Bredsdorff, L. / Pilegaard, K. et al. | 2018
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Multi-omics Analysis reveals that co-exposure to phthalates and metals disturbs urea cycle and choline metabolismSarigiannis, D. / Papaioannou, N. / Kapretsos, N. / Gabriel, C. / Distel, E. / de Oliveira, E. / Karakitsios, S. / Aggerbeck, M. / Barouki, R. et al. | 2018
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Antiandrogenic effects of gibberellins in the recombinant yeast androgen bioassayStypuła-Trębas, S. / Radko, L. / Jedziniak, P. / Posyniak, A. et al. | 2018
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Human tissue based sensitization assessment: set-up of an accurate prediction model for distinguishing skin sensitizers using a new assay adapted to hydrophobic substances and mixturesAndres, E. / Barry, M. / Hundt, A. / Dini, C. / Ferret, P.-J. et al. | 2018
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Cell-based screening of drug-induced metabolic dysfunctionSchwalfenberg, M. / McGarrigle, R. / Hayes, I. / Carey, C. / Hynes, J. et al. | 2018
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3D spheroid cultures from human astrocyte- and neuronal- like cells: New in vitro models to assess magnetite nanoparticle-induced adverse effects on CNSDe Simone, U. / Caloni, F. / Roccio, M. / Gribaldo, L. / Spinillo, A. / Coccini, T. et al. | 2018
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Maternal smoking and changes in drug metabolising enzymes in the human fetusZafeiri, A. / Filis, P. / Soffientini, U. / Lucendo-Villarin, B. / Douglas, A. / Shaw, S. / Iredale, J.P. / Swortwood, M.J. / Huestis, M.A. / Bellingham, M. et al. | 2018
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Effect of rocuronium on duration of ventilation after organophosphorus insecticide poisoning – A pilot randomised controlled trialDhanarisi, H.K.J. / Gawarammana, I. / Mohamed, F. / Eddleston, M. et al. | 2018
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An automated workflow for Adverse Outcome Pathway hypothesis generationDoktorova, T. / Exner, T.E. / Hardy, B. / Noffisat, O. et al. | 2018
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Predicting in silico the Direct-Peptide-Reactivity-Assay (DPRA) within the Allergic Contact Dermatitis framework: A module accounting for test variability and abiotic transformationsDetroyer, A. / Ivanova, H. / Eilstein, J. / Piroird, C. / Imbert, S. / Del Bufalo, A. / Popova, I. / Kuseva, C. / Karakolev, I. / Dimitrov, S. et al. | 2018
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Levels of heavy metals and essential minerals in hair samples of children with autism in Algeria: A case–control studyZebbiche, Y. / Bencherif, M.S. / Boughazi, H. / Aries, S. / Amziane, A. / Djidjik, R. / Alamir, B. et al. | 2018
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BioCelerate Toxicology Data Sharing initiative: Development of a centralized, searchable Preclinical Data Repository for the Biopharmaceutical IndustryBjerregaard, T.G. / Graziano, M. / Vock, E. / Kahlbaugh, G. / Houser, W. / Page, T. / Mera, K. / Fukushima, T. / Kuzumoto, M. / Frahm, S. et al. | 2018
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Discovery of urinary biomarkers for early detection of diabetic- induced chronic kidney diseasesKim, K.S. / Kim, J.S. / Kim, H.S. et al. | 2018
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A novel microtissue-based 3D human liver NASH model for drug discoveryRupp, J. / Strassfeld, T. / Steiert, S. / Guye, P. / Messner, S. / Kostadinova, R. et al. | 2018
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In vitro permeability assay using an epithelial model of Caco-2/HT29-MTX/Raji-B cells: enhancer aspects of a papain-cyclodextrin complexLopes, P.S. / Corazza, F.G. / Nambu, F.A.N. / Ernesto, J.V. / Varca, G.H.C. / Leite-Silva, V.R. / Andréo-Filho, N. et al. | 2018
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Molecular and chemical response signatures illustrate species differences of developing neural progenitor cells from human, mouse and ratMasjosthusmann, S. / Barenys, M. / Baumann, J. / Bendt, F. / Becker, D. / Deenen, R. / Förster, N. / Mosig, A. / Hübenthal, U. / Klose, J. et al. | 2018
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Liver-chips and liver spheroids as models to determine hepatic safety and metabolismFoster, A.J. / Chouhan, B. / Regan, S. / Rollison, H. / Amberntsson, S. / Andersson, L. / Srivastava, A. / Jang, K.-J. / Petropolis, D. / Kodella, K. et al. | 2018
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Use of chemical-specific adjustment factors in health risk assessments: A tale of two preservativesGoodman, J.E. / Pizzurro, D.M. / Lemay, J.C. / Lewandowski, T.A. / Zu, K. et al. | 2018
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Persistent organic pollutants, pre-pregnancy use of combined oral contraceptive and time-to-pregnancy in SELMA cohortBjörvang, R.D. / Gennings, C. / Lin, P.-I. / Hussein, G. / Kiviranta, H. / Rantakokko, P. / Ruokojärvi, P. / Damdimopoulou, P. / Bornehag, C.-G. et al. | 2018
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Glial-neuronal signaling mechanisms underlying the neurotoxic effects of manganesePopichak, K.A. / Afzali, M.F. / Kirkley, K.S. / Tjalkens, R.B. et al. | 2018
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Cutaneous innate immunity activation in response to xenobiotics: how do contact allergens manage this activation?Kerdine-Römer, S. et al. | 2018
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Nanomedicinal products and immunotoxicity assessment: an improved and integrated strategyGiannakou, C. / Geertsma, R.E. / de Jong, W.H. / van Loveren, H. / Vandebriel, R.J. / Park, M.V.D.Z. et al. | 2018
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Uncertainty analysis in risk assessments of chemicals have equal principles for protecting either human health or the ecosystemSmolders, E. / Verougstraete, V. et al. | 2018
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Environmental risk and eco-toxicology of nanomaterials: exposure driven methodologyRose, J. / Auffan, M. / Chaurand, P. / Borschneck, D. / Levard, C. / Labille, J. / Masion, A. / Bottero, J.-Y. et al. | 2018
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Advancing risk assessment of cosmetics using COSMOS in silico modelling and databasePaini, A. / Richarz, A.N. / Sala Benito, J.V. / Worth, A.P. et al. | 2018
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Capturing Toxicology with human and animal derived OrganoidsVries, R.G.J. et al. | 2018
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Determination of environmental persistent organic pollutants (POPs) in hair samples from wild terrestrial mammalsIatrou, E. / Tzatzarakis, M.N. / Vakonaki, E.K. / Papachristou, S. / Renieri, E. / Golokhvast, K. / Seryodkin, I. / Tsygankov, V. / Valerii, R. / Tsatsakis, A.M. et al. | 2018
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Evaluation of e-cigarette liquids on labelling, packaging and technical features prior the adoption of the Tobacco Products Directive (TPD) in multiple European countriesTzatzarakis, M.N. / Girvalaki, C. / Vardavas, A. / Stivaktakis, P. / Nosyrev, A. / Leon, G. / Tsatsakis, A.M. / Vardavas, C. et al. | 2018
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Protective effects of SIRT1 antagonist on diabetic-induced renal fibrosisKim, J.S. / Kim, K.S. / Kundu, A. / Kim, H.S. et al. | 2018
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Mineral mix diet composition for reprotoxicological experiments in vivo: Lithium saltTyshko, N.V. et al. | 2018
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Toxicology Out of The Box - an overview of the Lush PrizeRam, R. et al. | 2018
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Toxicity of ceramic nanoparticles in human alveolar epithelial A549 cells at the air-liquid interfaceFraga, S. / Bessa, M.J. / Brandão, M.F.P. / Fokkens, P. / Boere, J.F. / Leseeman, D. / Salmatonidis, A. / Viana, M. / Cassee, F.R. / Teixeira, J.P. et al. | 2018
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European Food Safety Authority (EFSA) protocol for the re-assessment of the safety for consumers of Bisphenol A (BPA)Croera, C. / Castoldi, A.F. / Putzu, C. / Barizzone, F. / Carmona, J. Cara / Gundert-Remy, U. et al. | 2018
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A comprehensive comparison of in vitro assays utilised to detect mitochondrial toxicityMaclennan, R.A. / Eakins, J. / Bauch, C. / Park, B. / Walker, P. et al. | 2018
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The membrane toxicology of rods and spheric zinc oxide nanoparticlesHarmaza, Y. / Tamashevski, A. / Jevdokimovs, D. / Viter, R. / Slobozhanina, E. et al. | 2018
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Chronic organophosphate exposure triggers ROS-mediated injuries at organismal and sub-organismal levels of non-target Drosophila melanogasterRoy, S. et al. | 2018
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Expression of aryl hydrocarbon receptor in the developing mouse brainKimura, E. / Maekawa, F. / Tohyama, C. et al. | 2018
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Use of read-across in EU approved biocidal active substances (focus on human health)Papadaki, P. / Airaksinen, A. / Antal, D. / Damsten, M. / Martinez, C. Estevan / Muller, G. / Myohanen, K. / Naeem, M.U. / Ruggeri, L. et al. | 2018
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Developing an adverse outcome pathway framework for carcinogenicity from alerts in an expert rule-based systemFoster, R. / Cayley, A. / Fisk, L. / Guesne, S. / Canipa, S. / Kane, S. et al. | 2018
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Updates and overview of derivation of subacute guidance values for contaminants in drinking water in JapanMatsumoto, M. / Kawamura, T. / Inoue, K. / Yamada, T. / Kobayashi, N. / Hirose, A. et al. | 2018
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Human induced pluripotent stem cell-derived neurospheres develop into electrically active neuronal networks which suit as an alternative method to study neurotoxicity in vitroNimtz, L. / Hofrichter, M. / Kabiri, Y. / Theiss, S. / Adjaye, J. / Fritsche, E. et al. | 2018
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Prevalence of food allergy among United Arab Emirates (UAE) population, a meta- analysis studyMustafa, N.E.M. et al. | 2018
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Hepatotoxicity of pyrrolizidine alkaloids in human hepatocytes and endothelial cellsGlück, J. / Ebmeyer, J. / Waizenegger, J. / Luckert, C. / Braeuning, A. / Lampen, A. / Hessel-Pras, S. et al. | 2018
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Structure-activity relationships of Baikal seal estrogen receptors and environmental phenolsYoshinouchi, Y. / Hirano, M. / Nakata, H. / Nomyamai, K. / Tanabe, S. / Kim, E.-Y. / Iwata, H. et al. | 2018
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Co-presence of mycotoxins in tunisian feed samplesJuan, C. / Oueslati, S. / Juan-García, A. / Mañes, J. / Berrada, H. et al. | 2018
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Research on environmental exposure and health effects in residents around mining areas in MongoliaHong, Y.S. / Seo, J.W. / Nam, S.H. / Altangerel, E. / Kim, D.S. et al. | 2018
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Effect of compounds Y on the barrier function of human iPSCs derived brain microvascular endothelial cellsYamashita, M. / Aoki, H. / Hashita, T. / Iwao, T. / Matsunaga, T. et al. | 2018
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Critical substances in bovine corneal opacity and permeability (BCOP) versus isolated chicken eye (ICE) assaysEhrenberg, S. / Burkhardt, S. / Werner, C. / Bachmann, N. / Allingham, P. / Wetzel, P. et al. | 2018
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High-throughput 3D brain model of iPSC-derived neurons and glia for prediction of neurotoxicity and safety pharmacologyRamakers, C. / Chang, C. / Wilschut, K. / Nicolas, A. / Olivier, T. / Lanz, H.L. / Trietsch, S.J. et al. | 2018
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Predicting skin sensitizers with confidence – using conformal prediction to determine applicability domain of GARDJohansson, H. / Forreryd, A. / Norinder, U. / Lindberg, T. / Lindstedt, M. et al. | 2018
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Evaluation of 3D-culture methods for the hepatic differentiation of human skin-derived stem cellsNatale, A. / Vanmol, K. / Arslan, A. / Van Vlierberghe, S. / Dubruel, P. / Van Erps, J. / Thienpont, H. / De Kock, J. / Rogiers, V. / Rodrigues, R.M. et al. | 2018
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In vitro antiproliferative effects of Fe3O4_BA loaded liposomesFarcas, C.G. / Moaca, E.A. / Coricovac, D. / Dehelean, C. / Loghin, F. et al. | 2018
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Cytotoxic activity of Zn(II)/Au(I), Zn(II)/Ag(I) and Ru(III) complexes with Schiff base Salen in human cancer and non-cancer cellsDinev, D.R. / Petrova, Z. / Zhivkova, T. / Spasov, R. / Georgieva, M. / Miloshev, G. / Patron, L. / Marinescu, G. / Culita, D.-C. / Alexandrova, R. et al. | 2018
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Pharmacological properties of a thrombin-like, inducer of platelet aggregation, purified from Cerastes cerastes venom: Elucidation of activated pathway signalingFatah, C. / Saoud, S. / Laraba-Djebari, F. et al. | 2018
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OpenRiskNet, an open e-infrastructure to support data sharing, knowledge integration and in silico analysis and modelling in risk assessmentExner, T.E. / Dokler, J. / Bachler, D. / Farcal, L.R. / Evelo, C.T. / Willighagen, E. / Jennen, D.G.J. / Jabocs, M. / Doganis, P. / Sarimveis, H. et al. | 2018
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ToxicBlend: Virtual screening of toxic compound with ensemble predictorsZaslavskiy, M. / Jegou, S. / Tramel, E.W. / Wainrib, G. et al. | 2018
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Impact of diabetes on gabapentin pharmacokinetics in patients with neuropathic painCosta, A.C.C. / Yamamoto, P.A. / Benzi, J.R.D.L. / Lauretti, G.R. / de Moraes, N.V. et al. | 2018
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Calcium supplementation of pied flycatcher females in a metal-polluted environment: protective effect against oxidative stress?Espín, S. / Sánchez-Virosta, P. / Ruiz, S. / Eeva, T. et al. | 2018
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Is there a relationship between bioaccessibility and bioavailability for metals?Lowney, Y.W. / Verougstraete, V. / Oller, A. et al. | 2018
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Skin sensitisation assessment of 2 biocide formulations: comparison of 3 alternative methodsCatoire, S. / Thelu, A. / Page, B. / Creusot, T. / Soum, S. / Beaudequin, L. / Lopez, B. / Martin, S. / Bree, F. / Ficheux, H.E. et al. | 2018
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Effects of exposure to e-cigarette aerosols compared with cigarette smoke on 3D human buccal and small airway cultures: a systems toxicology assessmentIskandar, A.R. / Sandro, S. / Shoaib, M. / Kondylis, A. / Xiang, Y. / Zanetti, F. / Frentzel, S. / Martin, F. / Ivanov, N.V. / Peitsch, M.C. et al. | 2018
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Assay ready frozen THP-1 cells can be used like a reagent in a human Cell Line Activation Test (h-CLAT) to measure the skin sensitizing potential of chemicalsMazurov, V. / Walbech, J. / Loa, A. / Wehmeier, O. et al. | 2018
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The malformation of Purkinje cells becomes the sensing tool for developmental neurotoxicity; its potential and limitationYoshida, S. / Iwamoto, S. / Fueta, Y. / Ueno, S. / Sekino, Y. / Nomura, Y. / Kanda, Y. et al. | 2018
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Predictive Tools and Databases for ToxicokineticsMadden, J.C. et al. | 2018
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The ToxTracker reporter assay detects indirect genotoxicity caused by high levels of oxidative stressvan Rossum, P. / Derr, R. / Racz, P. / Moelijker, N. / Brandsma, I. / Hendriks, G. et al. | 2018
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An autopsy case of diphenhydramine poisoningFurukawa, S. et al. | 2018
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Levels of rare earth elements in hair from a group of young Spanish adults (aged 20-24 years)Fernández, A. Peña / Angulo, S. / Bedmar, M.C. Lobo et al. | 2018
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The role of cross-species microphysiological systems in understanding target organ toxicity in Oncology drug projectsEwart, L. et al. | 2018
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Occupational exposure to bitumen fumesBorska, L. / Andrys, C. / Kremlacek, J. / Malkova, A. / Svadlakova, T. / Borsky, P. / Fiala, Z. et al. | 2018
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Stem cell derived human organ cells for toxicity testing in microfluidic devicesMandenius, C.-F.A. et al. | 2018
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PBPK/PD coupled HPG SB model to analyze the reproductive toxicity of EDs: Case study on mixture effects of DEHP and TCDDSharma, R.P. / Schuhmacher, M. / Kumar, V. et al. | 2018
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Clorgyline and N-acetyl-L-cysteine provide partial protection against the toxicity of synthetic cathinones and methamphetamine on SH-SY5Y humans cellsSoares, J. / Costa, V. / Bronze, S. / Gaspar, H. / Santos, S. / Bastos, M.D.L. / Carvalho, F. / Capela, J. et al. | 2018
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Evaluation of bile acids as additional markers for drug-induced liver injuryRiefke, B. et al. | 2018
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Anticancer potential of semi-volatile compounds present in cork: Cytotoxic mixture effects in human colorectal adenocarcinoma cellsOliveira, A.S. / Pinto, J. / Lopes, P. / Cabral, M. / Bastos, M.L. / Dias da Silva, D. / Guedes de Pinho, P. et al. | 2018
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Extended applicability domain with new solvent selection for the GARD platformJenvert, R.-M. / Larne, O. / Torstensdotter Mattson, U.I. / Johansson, H. et al. | 2018
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In vitro approaches to risk assess chemical mediated changes in thyroid functionHiggins, L.G. / Haines, C. / MacLeod, A.K. / Chatham, L.R. / Clark, G. / Princivalle, M. et al. | 2018
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How modern toxicology serves the societyHartung, T. et al. | 2018
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Effects of zinc chloride on Zebrafish locomotion, circadian rhythm, social behavior and memory: Correlation between toxicity and neurobehavior changesSarasamma, S. et al. | 2018
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K03 – Metabolism, Inflammation and CancerGooderham, N.J. et al. | 2018
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Spontaneous lesions associated with test article-unrelated deaths in repeated dose rat studiesPan, L. / McPherson, S.M. / Zhou, T. et al. | 2018
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Training to prepare human health undergraduate students to respond to biological incidentsFernández, A. Peña / Machado-Ferreira, F. / Lobo-Bedmar, M.C. et al. | 2018
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Natural antioxidants prevent contrast-induced nephropathy in an animal model: Results from a biochemical studyZisis, R. / Fragkiadoulaki, I. / Alegakis, A. / Karkala, F. / Vakonaki, E.K. / Apalaki, E. / Vaki, G.A. / Kovatsi, L. / Tsatsakis, A.M. / Mamoulakis, C. et al. | 2018
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Natural antioxidants prevent contrast-induced nephropathy in an animal model: Results from a cytological studyTsatsakis, A.M. / Fragkiadoulaki, I. / Kalogeraki, A. / Tsiaoussis, I. / Karkala, F. / Kalliantasi, K. / Stivaktakis, P. / Fragkiadaki, P. / Psycharakis, C. / Mamoulakis, C. et al. | 2018
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A high-content imaging approach for AOP development of kidney proximal tubule toxicityDi FIore, S. / Schmelter, F. / Ellinger, B. / Jarzina, S. / Mally, A. et al. | 2018
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Neurotoxicity in vivo and in vitro by glyphosateMartínez-Larrañaga, M.-R. / Rodríguez, J.-L. / Ares, I. / Lopez-Torres, B. / Martínez, M. / Roura-Martínez, D. / Anadon, A. / Martínez, M.-A. et al. | 2018
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Selective evaluation of potentially carcinogenic polycyclic aromatics in mineral oil by the DMSO based IP346 methodCarrillo, J.C. / Boogaard, P.J. et al. | 2018
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Global proteomic analysis of major metabolic tissues from Wistar rats chronically exposed to the contaminants bisphenol A and SAzevedo, L.F. / Carneiro, M.F.H. / Dechandt, C.R.P. / Cassoli, J.S. / Alberici, L.C. / Júnior, F. Barbosa et al. | 2018
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ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNTs – Comparative in vitro investigationsZiemann, C. / Reamon-Buettner, S.M. / Lison, D. / Bonner, J.C. / van den Brule, S. / Simon, S. / Creutzenberg, O.H. et al. | 2018
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Influence of dispersion method on silica nanoparticle size distribution/aggregation and their chronic toxicity in-vitroMurugadoss, S. / van den Brule, S. / Sebaihi, N. / Brassinne, F. / Mast, J. / Godderis, L. / Lison, D. / Hoet, P.H.M. et al. | 2018
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The PLATOX project: Combining in vitro and in vivo investigations to generate valid toxicity data for risk assessment of graphene nanoplateletsCreutzenberg, O.H. / Ziemann, C. / Schaudien, D. / Oliveira, H. / Farcal, L. et al. | 2018
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Sodium molybdate attenuates lipid accumulation in the livers of mice fed a diet deficient in methionine and cholineRyu, D.-Y.R. / Lee, S. et al. | 2018
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Dose-dependent sensitization effects of transcutaneously exposed acid-hydrolyzed wheat proteinCho, Y.-M. / Akagi, J.-I. / Mizuta, Y. / Toyoda, T. / Tamehiro, N. / Kimura, Y. / Adachi, R. / Ogawa, K. et al. | 2018
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Genetic damage in young swimmers exposed to pool disinfection by-productsAmaro, R.D.N. / Esteves, F.C. / Silva, S. / Costa, C. / Costa, S. / Teixeira, J.P. et al. | 2018
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Usage patterns of cosmetic products by pregnant womenNguyen, T. / Berrada-Gomez, M.-P. / Rielland, A. / Bellec, M. / Gil, S. / De Javel, D. / Ferret, P.-J. et al. | 2018
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Chromosomal aberrations and micronuclei structures after dermal exposure to polycyclic aromatic hydrocarbon and ultraviolet radiationMalkova, A. / Smejkalova, J. / Hamakova, K. / Kremlacek, J. / Svadlakova, T. / Borska, L. / Fiala, Z. et al. | 2018
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Polycyclic aromatic hydrocarbons in herbal medicinal productsVavvas, T. / Bode, G. et al. | 2018
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Suggestions for the OECD's extended one-generation reproductive toxicity study to further understand the temporality of endocrine-disrupting effects from chemical exposure: example using bisphenol AChoi, J. / Mune, W. / Joas, A. et al. | 2018
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In vitro model for the prediction of respiratory sensitizationChary, A. / Serchi, T. / Cambier, S. / Moschini, E. / Contal, S. / Hennen, J. / Ezendam, J. / Blömeke, B. / Gutleb, A.C. et al. | 2018
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Real-time monitoring of oxygen consumption of hepatocytes in a microbioreactorUhlig, K. / Gehre, C.P. / Kammerer, S. / Küpper, J.-H. / Coleman, D. / Püschel, G. / Duschl, C. et al. | 2018
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Development of a state-of-the-art multiple regression KY-method corresponding to the big data era and its application to fish toxicityYuta, K. et al. | 2018
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Systems toxicology approach for the assessment of zebrafish cardiotoxicityLi, R. / vom Berg, C. / Talikka, M. / Madan, S. / Dörpinghaus, J. / Fluck, J. / Szostak, J.G. / Martin, F. / Peitsch, M.C. / Hoeng, J. et al. | 2018
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Identifying potential analogues for read-across in Physiologically-Based Kinetic (PBK) modellingMadden, J.C. / Ebbrell, D.J. / Cronin, M.T.D. et al. | 2018
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LincRNA-RoR regulates the apoptotic function of p53 via targeting miR-204/MDM2 in human esophageal squamous cell carcinomaLiu, R. / Wang, T. / Shang, M. / Wang, X. / Zhang, P. et al. | 2018
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Empowering scientists in the use of new approach methods: the Altertox AcademyTenie, G.A. / Prachkovski, I. / Busquet, F. et al. | 2018
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The effect of diet-induced obesity on general and explorative toxicity parameters in Sprague-Dawley ratsRojas, J.M. / Bolze, F. / Thorup, I. / Nowak, J. / Dalsgaard, C.M. / Skydsgaard, M. / Berthelsen, L.O. / Keane, K.A. / Søeborg, H. / Sjögren, I. et al. | 2018
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One-month repeated cigarette smoke exposure of human organotypic bronchial epithelial cell cultureIto, S. / Ishimori, K. / Ishikawa, S. et al. | 2018
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3D NephroScreen: high throughput drug-induced nephrotoxicity screening on a proximal tubule-on-a-chip modelGijzen, L. / Vormann, M.K. / Hutter, S. / Vriend, J. / Trietsch, S.J. / Joore, J. / Wilmer, M. / Suter-Dick, L. / Masereeuw, R. / Lanz, H.L. et al. | 2018
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Introduction to the BMD approachSlob, W. et al. | 2018
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In vitro Cardiotoxicity evaluation on hiPSC using phenotypic analysisPerrier, A. / Postic, B. / Martins, M. / Rutault, L. / Buvat, A. / Bécourt-Lhote, N. / Claude, N. / Aerts, H. et al. | 2018
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Pulmonary Inflammatory Signaling Responses Induced by Saturated Aliphatic Aldehydes via Orphan G protein-coupled Receptor 124Cho, Y. / Kim, T.S. / Ryu, J.-C. et al. | 2018
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This poster abstract has been withdrawn| 2018
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A novel approach to chemical mixture risk assessment - Linking data from population based epidemiology and experimental animal testsBornehag, C.-G. / Gennings, C. et al. | 2018
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Is global chemical policy reaching its goals?Leinala, E. et al. | 2018
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Exciting challenges in the regulatory field of preclinical abuse liability testing of novel CNS-active drug candidates: can we cope?Teuns, G. et al. | 2018
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Regulatory aspects under REACH relating to the developmental immunotoxicity (DIT) cohort in the extended one-generation reproductive toxicity study (EOGRTS)Bichlmaier, I. / Rossi, L. / Sakha, P. / Leppäranta, O. / Huuskonen, H. et al. | 2018
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Adversity of changes in immune parameters and findings in developmental immunotoxicity studiesHessel, E.V. et al. | 2018
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Approaching the development of alternative testing methods using information available in the adverse outcome pathway knowledgebase (AOP-KB)Sachana, M. et al. | 2018
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In vitro models and opensource toxicokinetic databases to support quantitative in vitro to in vivo extrapolation for human risk assessmentClewell, H. et al. | 2018
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S – Cell proliferation and carcinogenesis: bad luck and the environmentCohen, S.M. et al. | 2018
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Developmental neurotoxicity study of zeta-cypermethrinNedopytanska, N. / Prodanchuk, M. / Kornuta, N. / Kolianchuk, Y. / Usenko, T. / Rashkivska, I. et al. | 2018
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Acute lead poisoning in a golden eagle from Italian Alps: An evaluation to metals exposure through blood and feathers analysisSquadrone, S. / Orusa, R. / Robetto, S. / Mantia, M. / Rizzi, M. / Colombero, G. / Parovel, E. / Abete, M.C. et al. | 2018
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High-throughput platform for rapid TEER measurement of Organ-on-a-Chip endothelial and epithelial tubulesStrijker, W. / Nicolas, A. / Olivier, T. / Lanz, H.L. / Trietsch, S.J. et al. | 2018
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Paracetamol (acetaminophen) may interfere with the human fetal ovary development in an ex vivo modelLecante, L.L. / Leverrier-Penna, S. / Lavoué, V. / Rolland, A.D. / Mazaud-Guittot, S. et al. | 2018
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Omics-based analysis of the impact of cigarette smoke and cessation in mouse liver and kidney following a 6-month exposureMatsumura, K. / Hirata, T. / Motohashi, Y. / Ito, S. / Mine, T. / Suzuki, H. et al. | 2018
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Benzo[a]pyrene induced regulation of mRNA translation and its impact on gene expressionSmit, E. / Caiment, F. / Piepers, J. / Kleinjans, J.C.S. / van den Beucken, T. et al. | 2018
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The applicability of zebra fish animal models for acute toxicity testing of silver nanoparticleWang, Y.-J. / Lee, Y.-H. et al. | 2018
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DNA adducts mapping as possible urban pollution biomarkerMedeiros, M.H.G. / Sanchez, A.B. / Di Mascio, P. et al. | 2018
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Inhalation exposure to cigarette smoke exacerbates vascular fibrosis and causes endothelial nitric oxide synthase uncoupling in streptozotocin-induced diabetic ratsDo, Q.V. / Park, K.-H. / Seo, Y.-S. / Lee, M.-Y. et al. | 2018
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Irritant-induced asthma to hypochlorite in mice due to impairment of the airway barrierVanoirbeek, J.A.J. / Van Den Broucke, S. / Pollaris, L. / Velde, G. Vande / Jonckheere, A.-C. / Decaesteker, T. / Verbeken, E. / Nemery, B. / Hoet, P.H.M. et al. | 2018
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Does altered gut barrier function facilitate food allergy development?Drønen, E.K. / Namork, E. / Dirven, H. / Hylland, K. / Nygaard, U.C. et al. | 2018
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Toxicological impacts of the fungicide isoprothiolane on common carp, Cyprinus carpio: a multi-biomarker assessmentHur, J.H. / Manoharan, S. / Hur, K.J. / Kim, J. et al. | 2018
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The Threshold of Toxicological Concern (TTC) approach can be applied to organosilicon compoundsSchmitt, B.G. / Jensen, E. / Laufersweiler, M.C. / Rose, J.L. et al. | 2018
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Cytogenetic activity of 2, 6-dimethylpyridine-N-oxide in a test for induction of chromosome aberrations in mouse bone marrow cells in vivoVasetska, O. / Zubko, O. / Prodanchuk, M. / Kravchuk, O. / Zhminko, P. et al. | 2018
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Estimation of the non-genotoxic effect level in vivo in bone marrow micronucleus tests for a rare disease drug candidateMueller, L. / Zeller, A. / Guerard, M. / Poirier, A. et al. | 2018
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Pathogenic gene profiles of Listeria monocytogenes isolated from food and environment in KoreaBae, Y. / Lee, Y.S. / Kim, B.J. / Choi, M.R. / Hwang, J.H. / Kim, S.H. / Kwak, H.S. et al. | 2018
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Concern for adverse effects of huperzine a when sold as an ingredient in food supplementsBredsdorff, L. / Pilegaard, K. et al. | 2018
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3-MCPD-induced organ toxicity is based on oxidative stressSchultrich, K. / Buhrke, T. / Henderson, C. / Wolf, R. / Braeuning, A. / Lampen, A. et al. | 2018
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Effect of n-butyl paraben on fertility of perinatally exposed F1 female progenyMaske, P.V. / Dighe, V.D. / Vanage, G.R. et al. | 2018
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Drug transporter expression in non-parenchymal liver cells in comparison to hepatocytesJoseph, C. / Rönnpagel, V. / Ullrich, A. / Runge, D. / Grube, M. et al. | 2018
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Toxicological evaluation of the interaction between circadian rhythm activators and general anestheticsAydin, A. / Kelleci, F. / Hamitoglu, M. et al. | 2018
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Safety evaluation of a human chimeric monoclonal antibody that recognizes the extracellular loop domain of claudin-2Hashimoto, Y. / Hata, T. / Tada, M. / Iida, M. / Watari, A. / Okada, Y. / Doi, T. / Kuniyasu, H. / Yagi, K. / Kondoh, M. et al. | 2018
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Identification of novel natural inhibitors of snake venom nucleotidases using a structure-based molecular docking studySaoud, S. / Chérifi, F. / Laraba-Djebari, F. et al. | 2018
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A mechanism of action classification method unifying toxicology and ecotoxicologyThomas, P. / Bauer, F. et al. | 2018
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ISafeRabbit® QSAR to predict skin and eye irritation potency of organic chemicalsDelannoy, M. / Charmeau-Genevois, C. / Bauer, F. / Sahigara, F. / Bicherel, P. / Mayer, N. / Thomas, P. et al. | 2018
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Interest of methemoglobine dosage in patients under dapsoneFatima Zohra, S. et al. | 2018
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Short-term exposure to ambient motor vehicle emissions perturb the human circulating miRNA genomeKrauskopf, J. / Caiment, F. / van Veldhoven, K. / Chadeau-Hyam, M. / Sinharay, R. / Fan Chung, K. / Cullinan, P. / Collins, P. / Barratt, B. / Kelly, F.J. et al. | 2018
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Schmidtea mediterranea as an alternative model to predict carcinogenicity via its stem cell responsesPloem, J.-P. / Wouters, A. / Willems, M. / Artois, T. / Smeets, K. et al. | 2018
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Mitigation of hypothetical on-target mechanosensory transduction risk in a TRPC6 antagonist project by evaluation of auditory function in the ratLiljevald, M. / Purbrick, S. / Tapp, R. / Rolf, M. / Redfern, W. et al. | 2018
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Introduction to Effectopedia: a platform for creating quantitative Adverse Outcome PathwaysSachana, M. et al. | 2018
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The EFSA WEB app based on PROAST: data table generationBokkers, B. et al. | 2018
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Pro-inflammatory responses to PM0.25 from airport and urban traffic emissionsHe, R. et al. | 2018
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An Evaluation of U.S. Forest Service Worksheets and their usefulness in modern risk assessment for exposure to pesticidesPhang, K. / Bonnar, D. et al. | 2018
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A homeopathic ophthalmic ointment containing Echinacea purpurea, Euphrasia officinalis and Calendula officinalis extracts: A PDE case reportTos, E. Gillio / Rodda, M.D. / Iavello, A. / Cattarello, L. Brunasso / Conto, A. et al. | 2018
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Effects of exposure of T cells to fine particulate matter and the influence of age; a prospective pilot studyZallouha, M. Al / Billet, S. / Landkocz, Y. / Borgie, M. / Poddighe, S. / Delepée, R. / Ledoux, F. / Cazier, F. / Vitagliano, J.J. / Visade, F. et al. | 2018
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EUROTOX Committee| 2018
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Dietary intake of PCDD/Fs by the population of Tarragona County, Catalonia, Spain. Temporal trends (1998-2018)González, N. / Marquès, M. / Nadal, M. / Domingo, J.L. et al. | 2018
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Utility of humanized mouse models for assessment of cytokine release induced by biotherapeuticsO'Donnell, L.M. et al. | 2018
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Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Metabolotes in H9c2 Cardiac Differentiated CellsReis-Mendes, A. / Carvalho, F. / Sousa, E. / Remião, F. / Bastos, M.D.L. / Costa, V.M. et al. | 2018
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Integrative Modeling and AOP-based Simulation of Developmental ToxicityKnudsen, T.B. et al. | 2018
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Adverse outcome pathway (AOP) -informed tiered testing to predict developmental or reproductive toxicity (DART) risks during new active substance R&DCurrie, R. / Delany, J. / Kidley, N. / Papachristos, K. / Wolton, K. / Cowie, D. / Richards-Doran, R. / Wang, S. / Modi, S. et al. | 2018
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Non-clinical safety considerations to support paediatric drug development – a regulatory updateBaldrick, P. et al. | 2018
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Immunotoxicity assessment of biotech products and small moleculesPallardy, M. et al. | 2018
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Repurposing of new medicines: opportunities and challengesRoberts, R.A. et al. | 2018
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The Nrf2-antioxidant response element signaling pathway controls fibrosis and autoimmunity in sclerodermaBatteux, F. et al. | 2018
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Neurocognitive effects of air pollutionSunyer, J. et al. | 2018
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Environmental carcinogenesis: when Nrf2 and the anti-oxidant response would drive the clonal evolution in colorectal cancerHuc, L. / Surya, R. / Dalleau, S. / Baradat, M. / Gueraud, F. / Pierre, F. et al. | 2018
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Mitochondrial toxicity and oxidative stress: Defining the tipping point between adaptive and adverse effects for consumer safety risk assessmentWestmoreland, C. / Cooper, S. / Guo, J. / Li, J. / Middleton, A. / Reynolds, J. / Peng, S. / van de Water, B. / White, A. / Yuan, H. et al. | 2018
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"TKPlate": A web-based platform for toxicokinetic modelling in food safetyQuignot, N. / Wiecek, W. / Amzal, B. / Dorne, J.-L.C.M. et al. | 2018
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Combination of energy drink and alcohol and its associated toxicityArbo, M.D. / Costa-Valle, M. / Tonietto, B. / Altknecht, L. / Duarte, C. / Garcia, S.C. / Dallegrave, E. / Leal, M.B. et al. | 2018
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The validation of GARDskinSandberg, P. / Agemark, M. / Johansson, A. / Gradin, R. / Forreryd, A. / Larne, O. / Edwards, A. / Hoepflinger, V. / Burleson, F. / Gehrke, H. et al. | 2018
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Can we do better with paracetamol poisoning in rural Asia? – A model based approach to reduce cost of management of paracetamol poisoning in Sri LankaPathiraja, V.M. / Gawarammana, I.B. / Buckley, N.A. / Mohamed, F. / Jayamanna, S.F. / Dawson, A.H. et al. | 2018
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(Eco)toxicity assessment of commercial engineered nanomaterials for plastic industry in zebrafishPassos, M. / Pinheiro, I. / Vieira, A. / Martins, J.C. / Campos, A. / Espiña, B. et al. | 2018
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Relationship between developmental toxicity of multi-wall carbon nanotubes and lung inflammation in pregnant mice after repeated intratracheal instillationHojo, M. / Kobayashi, N. / Hasegawa, Y. / Sakamoto, Y. / Murakami, S. / Yamamoto, Y. / Tada, Y. / Maeno, A. / Kubo, Y. / Ando, H. et al. | 2018
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Risk assessment and mechanism of toxicity of mycosynthesised silver nanoparticles to prokaryotic and eukaryotic modelGupta, I.R. / Rai, M.K. et al. | 2018
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A comparative in vitro investigation on the cardiotoxicity of two tyrosine kinase inhibitors: Regorafenib and lenvatinibGunaydin, A. / Boran, T. / Jannuzzi, A.T. / Alpertunga, B. et al. | 2018
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NFIL-3 regulates dendritic cells functions following nickel and cobalt exposurePallardy, M. / Bechara, R. / Nabhan, M. / Hullo, M. et al. | 2018
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Evaluation of the dose-response and fate in the lung and pleura of chrysotile containing brake dust compared to chrysotile or crocidolite asbestos in a 28 day inhalation toxicology studyToth, B. / Bernstein, D.M. / Rogers, R.A. / Kunzendorf, P. / Ernst, H. et al. | 2018
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Guidance for the risk assessment of enzyme-containing consumer productsKruszewski, F.H. / Concoby, B. / Simonsen, M. / Bookstaff, R. / Baccam, M. / Paschal, J. et al. | 2018
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Assessing acute inhalation exposure to hydrogen fluoride from thermal runaway of lithium-ion batteriesHercegovac, J. / Frangos, J. et al. | 2018
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Investigation of the effects of infrared rays on DNA strand in hot environment workers by comet assayKanbur, S. / Beceren, A. / Aydemir, S. / Uzun, M.F. et al. | 2018
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Next generation safety assessment strategy based on combined use of in silico toolsGranitzny, A. / Heinz, S. / Kawamoto, T. / Fuchs, A. / Fautz, R. et al. | 2018
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Pouteria ramiflora (Sapotaceae) leaves extract increases the antiproliferative and pro-apoptotic effects of cisplatin in HepG2 cellsCólus, I.M.S. / Tuttis, K. / Serpeloni, J.M. / Varanda, E.A. / Santos, L.C. / Vilegas, W. / Martínez-Lopez, W. et al. | 2018
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Hierarchical Bayesian exposure assessment of dietary polycyclic aromatic hydrocarbons in 3–6 year old FinnsHirvonen, T.M. / Hokkanen, M. / Pasonen, P. / Uusitalo, L. / Erkkola, M. / Korkalo, L. / Tuominen, P. / Mikkelä, A. et al. | 2018
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In vitro study of the cytotoxic effects of microcystin-LR, cylindrospermopsin and their mixture in the neuronal SH-SY5Y cell lineHinojosa, M.G. / Gutierrez-Praena, D. / Prieto, A.I. / Espinar-López, L. / Cameán, A.M. / Jos, A. et al. | 2018
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Characterization of drug metabolizing enzymes, transporters and permeation in a human organotypic corneal tissue modelKaluzhny, Y. / Kinuthia, M. / Truong, T. / Lapointe, A. / Klausner, M. / Letasiova, S. / Hayden, P. et al. | 2018
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Inter- and intra-laboratory reproducibility of the in vitro photo-toxicity test using 3D reconstructed human epidermis modelKandarova, H. / Liskova, A. / Milasova, T. / Letasiova, S. et al. | 2018
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Primary human hepatocyte spheroid generation and performance in different culture systemsBuesch, S. / Bunger, M. / Schroeder, J. / Stosik, M. et al. | 2018
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Evaluation of the cytotoxicity of cocaine and adulterants in precursor cells of the gliaRocha, R.A. / Figueroa, J. / Manzo, R. / Diaz, D. / Vasquez, A. / Soto, D. / Duffau, B. / Triviño, I. et al. | 2018
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Development of a human autologous 3-cell cytokine release assay that models the vascular wall in vitroKawai, R. / Ahmetaj-Shala, B. / Shih, C.C. / Marei, I. / Bhatti, K. / Kirkby, N.S. / Mitchell, J.A. et al. | 2018
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Prediction of drug-induced liver injuryGhafourian, T. / Baricicova, M. et al. | 2018
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Ligand based and structural based modeling for the understanding, classification and prediction ofmitochondrial toxicityGómez-Tamayo, J.C. / Troger, F. / Pastor, M. / Norinder, U. / Zdrazil, B. / Ecker, G. et al. | 2018
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Large-scale in silico screening of compounds contained in printing inks for food packaging materialsSmieško, M. / Don, C. / Meuwly, R. / Kucsera, S. / Brüschweiler, B.J. et al. | 2018
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Use of in silico methods in IATA for skin corrosion and irritationAbe, A. / Sezaki, T. / Kinoshita, K. et al. | 2018
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Polymethoxyflavones prevent benzo[a]pyrene/dextran sodium sulfate-induced colorectal carcinogenesis through modulating xenobiotic metabolism in ICR micePan, M.-H. / Wu, J.-C. / Wang, Y.-J. / Ho, C.-T. et al. | 2018
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Monitoring of triclosan and parabens in amniotic fluidKarzi, V. / Katsikantami, I. / Tzatzarakis, M.N. / Vakonaki, E.K. / Xezonaki, P. / Stratidakis, A. / Iliaki, E. / Sifakis, S. / Rizos, A. / Tsatsakis, A.M. et al. | 2018
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Exposure to environmental levels of polycyclic aromatic hydrocarbons leads to epigenetic modulation in a rat modelDuca, R.C. / Grova, N. / Gosh, M. / Hoet, P.H.M. / Vanoirbeek, J.A.J. / Appenzeller, B.M.R. / Godderis, L. et al. | 2018
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RVis: a freely available modelling platformLoizou, G.D. et al. | 2018
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Case study: Exposure to mixtures of chemicals in a human study and verification of aggregated exposure models with real-life dataDirven, H. / Andreassen, M. / Karrer, C. / von Goetz, N. / Sakhi, A.K. / Husøy, T. et al. | 2018
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In vitro toxicogenomic and proteomic assessment of e-cigarette aerosol compared to cigarette smokeVerrastro, I. / Haswell, L. / Corke, S. / Baxter, A. / Thorne, D. / Breheny, D. / Minet, E. / Gaca, M. et al. | 2018
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Evaluation of prostate cancer volatilome: An in vitro approachLima, A.R. / Araújo, A.M. / Pinto, J. / Jerónimo, C. / Henrique, R. / Bastos, M.D.L. / Carvalho, M. / Guedes de Pinho, P. et al. | 2018
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Determining mechanisms of mitochondrial toxicity using Agilent Seahorse XF TechnologyRomero, N. / Swain, P.M. / Dranka, B.P. et al. | 2018
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Editorial Board| 2018
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Synthetic cannabinoids enhance neuronal differentiation in neuroblastoma cells at in vivo relevant concentrationsAlexandre, J. / Carmo, H. / Carvalho, F. / Silva, J.P. et al. | 2018
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Mechanisms of adult and developmental immunotoxicityDietert, R.R. et al. | 2018
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Recent advances on novel translational kidney safety biomarkers and their use in the value chainGautier, J.-C. et al. | 2018
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Challenges in the assessment of reproductive toxicology of anti-obesity drugsBolze, F. / Rojas, J.M. / Bhuwania, R. / Egecioglu, N.E. / Dalgaard, M. / Andersen, L.W. et al. | 2018
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The discovery of innovative medicines with the Right Safety to increase R&D productivityHornberg, J.J. et al. | 2018
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K02 – Nrf2 and its futureYamamoto, M. et al. | 2018
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H – Big data for biologists: A maths in medicine case studyNandi, M. et al. | 2018
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Requirement of Nrf2 for termination of liver regeneration caused by acute proliferative responseTakasu, S. / Ishii, Y. / Kijima, A. / Ogawa, K. / Umemura, T. et al. | 2018
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A lipase biosensor using digital camera for the determination of neurotoxic compoundsPohanka, M. / Zakova, J. / Sedlacek, I. et al. | 2018
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Toxicity of synthetic cathinones in human kidney (HK-2) cellsCarvalho, T. / Vaz, I. / Araújo, A.M. / Remião, F. / Bastos, M.D.L. / Carvalho, M. et al. | 2018
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My family and other animals: comparative requirements for human and animal metabolism studiesMcEwen, A. et al. | 2018
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P19-06 Retrospective histopathology evaluation of respiratory tract tissues from two rat 90-day OECD 413 inhalation studies: Tobacco Heating System 2.2 versus Mentholated Tobacco Heating System 2.2 compared with conventional and mentholated reference cigarettesOviedo, A. / Neves, P.F. / Wong, E.T. / Foong, C. / Vuillaume, G. / Sciuscio, D. / Peitsch, M.C. / Vanscheeuwijck, P. et al. | 2018
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MEtabolomics standaRds Initiative in Toxicology (MERIT)Kamp, H. / Beger, R. / Dorne, J.-L.C.M. / Ebbels, T. / Ekman, D. / Guillou, C. / Goetz, A. / Loizou, G. / Leonards, P. / van Ravenzwaay, B. et al. | 2018
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Transcriptional changes underlying cerium dioxide nanoparticle modulation of allergen induced type II airway inflammationMeldrum, K. / Robertson, S.B. / Gant, T.W. / Tetley, T.D. / Smith, R. / Leonard, M.O. et al. | 2018
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Exploring the usefulness of morphological profiling of cells to study toxicity mechanismsGeorgieva, P. / Schaal, W. / Spjuth, O. et al. | 2018
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Whole-genome expression analysis in THP-1 macrophage-like cells exposed to diverse metal-containing nanomaterialsRössner, P. / Brzicova, T. / Libalova, H. / Vrbova, K. / Sikorova, J. / Philimonenko, V. / Klema, J. / Topinka, J. et al. | 2018
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Characterization of the TiO2 E171 food additiveBrassinne, F. / De Vos, S. / Verleysen, E. / De Temmerman, P.-J. / Ledecq, M. / Mast, J. et al. | 2018
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Microsomal metabolism and mutagenicity of cis- and trans-anetholeFuhlbrueck, J.A. / Schwind, E.C. / Lencioni, A. / Carlsson, M.J. / Cartus, A.T. et al. | 2018
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Role of Hif-1a and its target gene PTP4A3 in regulating cell proliferation during benzene exposurePu, Y. / Sun, R. / Sun, F. / Zhang, J. / Yin, L. / Man, Z. et al. | 2018
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Olive-derived hydroxytyrosol shows anti-inflammatory effect without immunotoxicityYonezawa, Y. / Nejishima, H. / Takeda, Y. / Imai, K. / Ogawa, H. et al. | 2018
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Effect of kynurenic acid and metformin on mercury-exposed SH-SY5Y cellsEngin, A.B. / Karakisa, D. / Engin, E.D. et al. | 2018
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Quercetin attenuates ergotamine induced toxicity in rat liver hepatocytesFard, J. Khalili / Sattari, M. / Hamzeiy, H. / Eghbal, M.A. / Jafari, S. et al. | 2018
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Identification of potential tattoo allergens by combining in vitro assays and chemical analysisSchreiver, I. / Kühn, M. / Yildirim, S. / Eschner, L.-M. / Hutton-Carlson, K. / Serup, J. / Luch, A. et al. | 2018
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Ecotoxicological and toxicological assessment of substances in wastewater: making an informed decisionLovsin Barle, E. / Burri, E. / Hermann, F. / Niederer, C. / Trudel, D. / Arnold, C. et al. | 2018
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Integrated genotoxicity testing (Pig-a and MNT) within 28-day mouse study – A case study with Meptyldinocap metabolite, X12335709Aggarwal, M. / Murphy, L. / Terry, C. / Donner, E.M. et al. | 2018
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A proof-of-concept study: evaluating the applicability of high-throughput screening data and read-across tools for food relevant chemicalsNguyen, J.L. / Maier, A. / Ovesen, J. / Kleinstreuer, N. / Judson, R. / Krishan, M. et al. | 2018
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Identification of oxidative stress potential in phenolic compounds and their link to liver injurySchimming, J.P. / Bischoff, L.J.M. / ter Braak, B. / van de Water, B. et al. | 2018
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Characterization of a lung/liver organ-on-a-chip modelBovard, D. / Sandoz, A. / Morelli, M. / Trivedi, K. / Marescotti, D. / Frentzel, S. / Luettich, K. / Hoeng, J. et al. | 2018
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Differentiation of human pluripotent stem cells (hPSC) into neurons: A fast, reproducible and inducible system for neurotoxicity screeningAleksic, J. / Geti, I. / Apic, G. / Stoop, A. / Kotter, M. et al. | 2018
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The THP-1 Toolbox: A new method that integrates the 4 key events of skin sensitizationClouet, E. / Raffalli, C. / Damiens, M.-H. / Pallardy, M. / Ferret, P.-J. / Kerdine-Römer, S. et al. | 2018
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Cell-type specific effects of using two valproic acid isomers in the neural embryonic stem cell testde Leeuw, V.C. / Hessel, E.V. / Piersma, A.H. et al. | 2018
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Imaging and computational modelling to unravel the dynamics of the oxidative stress pathway upon repeated perturbationKuijper, I.A. / Bischoff, L.J.M. / Noort, D. / Langenberg, J.P. / van de Water, B. / Beltman, J. et al. | 2018
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Development of an in silico model to evaluate in vivo chromosome damaging potential of chemicalsVan Bossuyt, M. / Raitano, G. / Van Hoeck, E. / Rogiers, V. / Benfenati, E. / Mertens, B. et al. | 2018
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Evaluation of biomarkers for haemocomopatibility of polymer biomaterialsMiyajima-Tabata, A. / Komoriya, K. / Tanaka, M. / Hiruma, H. / Kato, R. / Haishima, Y. et al. | 2018
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Toxicogenomics of gold nanoparticles in a marine fish: linkage to established biomarkersTeles, M. / Reyes-López, F. / Balasch, J.C. / Guimarães, L. / Tort, L. / Oliveira, M. et al. | 2018
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Using the SENS-IS assay, to assess skin sensitization hazard of commercial cosmetics finished productsCottrez, F. / Boitel, E. / Groux, H. et al. | 2018
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AllerCatPro – Prediction of protein allergenicity potential from the protein sequenceMaurer-Stroh, S. / Krutz, N.L. / Kern, P.S. / Gunalan, V. / Nguyen, M.N. / Limviphuvadh, V. / Gerberick, G.F. et al. | 2018
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Prediction of adverse male reproductive health effects by integrating in vitro data and physiologically-based kinetic modellingTaxvig, C. / Scholze, M. / Kortenkamp, A. / Boberg, J. / Svingen, T. / Ermler, S. / Hermann, S.S. / Lykkeberg, A.K. / Pedersen, M. / Hass, U. et al. | 2018
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EPA and EFSA approaches for benchmark dose modelingDavis, A. et al. | 2018