Bioorganic and Medicinal Chemistry
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 3065
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The recent progress of isoxazole in medicinal chemistryZhu, Jie / Mo, Jun / Lin, Hong-zhi et al. | 2018
- 3076
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Design, synthesis and biological evaluation of benzofuran appended benzothiazepine derivatives as inhibitors of butyrylcholinesterase and antimicrobial agentsMostofi, Manizheh / Mohammadi Ziarani, Ghodsi / Lashgari, Negar et al. | 2018
- 3096
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Exploiting polarity and chirality to probe the Hsp90 C-terminusForsberg, Leah K. / Davis, Rachel E. / Wimalasena, Virangika K. et al. | 2018
- 3111
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Synthesis and characterization of radioiodinated 3-phenethyl-2-indolinone derivatives for SPECT imaging of survivin in tumorsIshikawa, Natsumi / Fuchigami, Takeshi / Mizoguchi, Tatsuya et al. | 2018
- 3117
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Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairmentLiu, Wenwen / Wang, Huan / Li, Xiaokang et al. | 2018
- 3126
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Osteoblastic differentiation on hydrogels fabricated from Ca2+-responsive self-assembling peptides functionalized with bioactive peptidesTsutsumi, Hiroshi / Kawamura, Megumi / Mihara, Hisakazu et al. | 2018
- 3133
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Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitorsNgo, Van T.H. / Hoang, Van-Hai / Tran, Phuong-Thao et al. | 2018
- 3145
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Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistryCao, Jiangying / Ma, Chunhua / Zang, Jie et al. | 2018
- 3158
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Novel amidrazone derivatives: Design, synthesis and activity evaluationZhou, Hua / Wang, Zhi Sen / Liu, Xin Hua et al. | 2018
- 3166
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Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptidesLaqua, Katja / Klemm, Marcel / Richard-Greenblatt, Melissa et al. | 2018
- 3191
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Novel 8-hydroxyquinoline derivatives targeting β-amyloid aggregation, metal chelation and oxidative stress against Alzheimer's diseaseYang, Xuelian / Cai, Pei / Liu, Qiaohong et al. | 2018
- 3202
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Structure-activity relationship of clovamide and its related compounds for the inhibition of amyloid β aggregationTsunoda, Tatsuhiko / Takase, Mio / Shigemori, Hideyuki et al. | 2018
- 3210
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Applications of a novel biodetection system to saliva using protein fingerprints with data processingTominaga, Yuki / Usui, Kenji / Hirata, Akiyoshi et al. | 2018
- 3217
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Synthesis and biological evaluation of 2, 4-disubstituted phthalazinones as Aurora kinase inhibitorsWang, Wei / Feng, Xiu / Liu, Huan-Xiang et al. | 2018
- 3227
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Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulatorsGerlach, Kai / Hobson, Scott / Eickmeier, Christian et al. | 2018
- 3242
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Design, synthesis and evaluation of benzoheterocycle analogues as potent antifungal agents targeting CYP51Zhao, Shizhen / Wei, Peng / Wu, Mengya et al. | 2018
- 3254
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Luminescent europium sensors for specific detection of 8-oxo-dGTP by time-gated fluorescenceFuchi, Yasufumi / Fukuda, Takashi / Sasaki, Shigeki et al. | 2018
- 3261
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Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3, 5-disubstituted piperidine to improve pharmacokinetic profileTokuhara, Hidekazu / Imaeda, Yasuhiro / Fukase, Yoshiyuki et al. | 2018
- 3287
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Efficiency of newly prepared thiazole derivatives against some cutaneous fungiOuf, Salama A. / Gomha, Sobhi M. / Eweis, Mohamed et al. | 2018
- 3296
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Design and synthesis of 2, 6-disubstituted-8-amino imidazo[1, 2a]pyridines, a promising privileged structureBoulahjar, Rajaa / Rincon Arias, Angela / Bolteau, Raphaël et al. | 2018
- 3308
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Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitorsWang, Chenglin / Zhu, Mingfei / Lu, Xiuhong et al. | 2018
- 3321
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Synthesis and structure–activity relationship studies of MI-2 analogues as MALT1 inhibitorsWu, Guolin / Wang, Haixia / Zhou, Wenhui et al. | 2018
- 3345
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Discovery of bicyclo[3, 3, 1]non-2-ene as a novel skeleton for HIF-1 inhibitorsUeda, Hiroki / Yoshimori, Atsushi / Nakamura, Hiroyuki et al. | 2018
- 3352
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Conversion of iodine to fluorine-18 based on iodinated chalcone and evaluation for β-amyloid PET imagingKaide, Sho / Ono, Masahiro / Watanabe, Hiroyuki et al. | 2018
- 3359
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Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxiaKhdour, Omar M. / Bandyopadhyay, Indrajit / Chowdhury, Sandipan Roy et al. | 2018
- 3370
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Novel oxazolxanthone derivatives as a new type of α-glucosidase inhibitor: synthesis, activities, inhibitory modes and synergetic effectDing, Sen-Miao / Lan, Tian / Ye, Gao-Jie et al. | 2018
- 3379
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Design and synthesis of new antitumor agents with the 1, 7-epoxycyclononane framework. Study of their anticancer action mechanism by a model compoundMontaña, Ángel M. / Lorenzo, Julia / Ponzano, Stefano et al. | 2018
- 3399
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Straightforward hit identification approach in fragment-based discovery of bromodomain-containing protein 4 (BRD4) inhibitorsBorysko, Petro / Moroz, Yurii S. / Vasylchenko, Oleksandr V. et al. | 2018
- 3406
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An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a convenient Fluorescence Imaging Plate Reader assayStevenson, Ralph J. / Azimi, Iman / Flanagan, Jack U. et al. | 2018
- 3414
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Molecular modeling, synthesis, antibacterial and cytotoxicity evaluation of sulfonamide derivatives of benzimidazole, indazole, benzothiazole and thiazoleNaaz, Farha / Srivastava, Ritika / Singh, Anuradha et al. | 2018
- 3429
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Design, synthesis and biological evaluation of phosphopeptides as Polo-like kinase 1 Polo-box domain inhibitorsLin, Tong-yuan / Min, Hong-ping / Jiang, Cheng et al. | 2018
- 3438
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Drug efficacy of novel 3-O-methoxy-4-halo disubstituted 5, 7-dimethoxy chromans; evaluated via DNA gyrase inhibition, bacterial cell wall lesion and antibacterial prospectivePonnusamy, Thangarasu / Alagumuthu, Manikandan / Thamaraiselvi, S. et al. | 2018
- 3453
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Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeusLiang, Hai / Zhou, Guangfeng / Ge, Yunhui et al. | 2018
- 3461
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Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) SinclairPrabha, B. / Neethu, S. / Krishnan, S. Lekshmy et al. | 2018
- 3468
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Dual emissive bispyrene peptide probes for highly sensitive measurements of trypsin activity and evaluation of trypsin inhibitorsSato, Daisuke / Kondo, Takuya / Kato, Tamaki et al. | 2018
- 3474
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Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cellsBatran, Rasha Z. / Kassem, Asmaa F. / Abbas, Eman M.H. et al. | 2018
- 3491
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Design, synthesis and biological evaluation of pyrimidine derivatives as novel CDK2 inhibitors that induce apoptosis and cell cycle arrest in breast cancer cellsWang, Yiting / Chen, Yanmei / Cheng, Xiaoling et al. | 2018
- 3502
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Chiral analogues of (+)-cyclazosin as potent α1B-adrenoceptor selective antagonistSagratini, Gianni / Buccioni, Michela / Marucci, Gabriella et al. | 2018
- 3514
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Optimized synthesis and antiproliferative activity of desTHPdactylolidesChen, Guanglin / Wang, Rubing / Vue, Bao et al. | 2018
- 3521
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Synthesis of 4′-C-aminoalkyl-2′-O-methyl modified RNA and their biological propertiesKoizumi, Kana / Maeda, Yusuke / Kano, Toshifumi et al. | 2018
- 3535
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Novel carbamate-linked quaternary ammonium lipids containing unsaturated hydrophobic chains for gene deliveryZhou, Hengjun / Yang, Jian / Du, Yanyan et al. | 2018
- 3541
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Anthranilic diamides derivatives as potential ryanodine receptor modulators: Synthesis, biological evaluation and structure activity relationshipLiu, Jing-Bo / Li, Feng-Yun / Dong, Jing-Yue et al. | 2018
- 3551
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Vinyldiaminotriazine-acridine conjugate as G-quadruplex alkylating agentHazemi, Madoka E. / Onizuka, Kazumitsu / Kobayashi, Tomohito et al. | 2018
- 3559
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Discovery and synthesis of 6, 7, 8, 9-tetrahydro-5H-pyrido[4, 3-c]azepin-5-one-based novel chemotype CCR2 antagonists via scaffold hopping strategyQin, Li-Huai / Wang, Zhi-Long / Xie, Xin et al. | 2018
- 3573
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Facilely accessible quinoline derivatives as potent antibacterial agentsTeng, Peng / Li, Chunhui / Peng, Zhong et al. | 2018
- 3580
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Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonistsStepniewski, Tomasz Maciej / Torrens-Fontanals, Mariona / Rodríguez-Espigares, Ismael et al. | 2018
- 3588
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Pyrroloquinoline scaffold-based 5-HT6R ligands: Synthesis, quantum chemical and molecular dynamic studies, and influence of nitrogen atom position in the scaffold on affinityGrychowska, Katarzyna / Kurczab, Rafał / Śliwa, Paweł et al. | 2018
- 3596
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Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugsPileggi, Elisa / Serpi, Michaela / Andrei, Graciela et al. | 2018
- 3610
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Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisininÇapcı Karagöz, Aysun / Reiter, Christoph / Seo, Ean-Jeong et al. | 2018
- 3619
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Synthesis and biological evaluation of irreversible EGFR tyrosine kinase inhibitors containing pyrido[3, 4-d]pyrimidine scaffoldZhang, Hao / Wang, Jin / Zhao, Hong-Yi et al. | 2018
- 3634
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Synthesis and biophysical properties of 5′-thio-2′, 4′-BNA/LNA oligonucleotideIslam, Md Ariful / Fujisaka, Aki / Mori, Shohei et al. | 2018
- 3639
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Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1, 3, 6-trisubstituted 1, 4-diazepan-7-onesMurafuji, Hidenobu / Sugawara, Hajime / Goto, Megumi et al. | 2018
- 3654
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Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylaseTaha, Muhammad / Rashid, Umer / Imran, Syahrul et al. | 2018
- 3664
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Cyclic biphalin analogues with a novel linker lead to potent agonist activities at mu, delta, and kappa opioid receptorsRemesic, Michael / Macedonio, Giorgia / Mollica, Adriano et al. | 2018
- 3668
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Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitorsTóth, Krisztián / Höfner, Georg / Wanner, Klaus T. et al. | 2018
- 3688
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Identification of novel thiazolo[5, 4-d]pyrimidine derivatives as human A1 and A2A adenosine receptor antagonists/inverse agonistsVarano, Flavia / Catarzi, Daniela / Falsini, Matteo et al. | 2018
- 3696
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Synthesis, structure-activity relationship and molecular docking studies of 3-O-flavonol glycosides as cholinesterase inhibitorsMughal, Ehsan Ullah / Javid, Asif / Sadiq, Amina et al. | 2018
- 3707
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Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysisSaeed, Aamer / Saddique, Gufran / Ali Channar, Pervaiz et al. | 2018
- 3716
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Design, synthesis, and biological evaluation of novel biphenyl-4-carboxamide derivatives as orally available TRPV1 antagonistsOka, Hiromasa / Yonezawa, Koichi / Kamikawa, Akio et al. | 2018
- 3727
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Corrigendum to "A study of 2-component i, i + 3 peptide stapling using thioethers" [Bioorg. Med. Chem. 26(6) (2018) 1203–1205]St. Louis, Lauren E. / Rodriguez, Tayliz M. / Waters, Marcey L. et al. | 2018
- 3728
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Corrigendum to "Structure–activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures" [Bioorg. Med. Chem. 23 (2015) 1601–1612]Nowotarski, Shannon L. / Pachaiyappan, Boobalan / Holshouser, Steven L. et al. | 2018
- III
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Graphical abstract TOC continued| 2018
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Editorial Board| 2018
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Graphical abstract TOC| 2018