Bioorganic and Medicinal Chemistry
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 3463
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Graphical contents list| 2008
- 3482
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Structural insights into how irreversible inhibitors can overcome drug resistance in EGFRMichalczyk, Anja / Klüter, Sabine / Rode, Haridas B. et al. | 2008
- 3489
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1-(2-Carboxyindol-5-yloxy)propan-2-ones as inhibitors of human cytosolic phospholipase A2a: Synthesis, biological activity, metabolic stability, and solubilityFritsche, A. / Elfringhoff, A. S. / Fabian, J. et al. | 2008
- 3489
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1-(2-Carboxyindol-5-yloxy)propan-2-ones as inhibitors of human cytosolic phospholipase A2α: Synthesis, biological activity, metabolic stability, and solubilityFritsche, Alexandra / Elfringhoff, Alwine Schulze / Fabian, Jörg et al. | 2008
- 3501
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Synthesis and DNA-cleaving activity of lactenediynes conjugated with DNA-complexing moietiesBanfi, Luca / Basso, Andrea / Bevilacqua, Elisabetta et al. | 2008
- 3519
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Potent anti-prostate cancer agents derived from a novel androgen receptor down-regulating agentPurushottamachar, Puranik / Khandelwal, Aakanksha / Vasaitis, Tadas S. et al. | 2008
- 3530
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Carbonic anhydrase activators: Activation of the human tumor-associated isozymes IX and XII with amino acids and aminesPastorekova, Silvia / Vullo, Daniela / Nishimori, Isao et al. | 2008
- 3537
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N-1H-Benzimidazol-5-ylbenzenesulfonamide derivatives as potent hPXR agonistsBenod, Cindy / Subra, Guy / Nahoum, Virginie et al. | 2008
- 3550
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Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulatorFrezza, Marine / Soulère, Laurent / Reverchon, Sylvie et al. | 2008
- 3557
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Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptaneBissel, Philippe / Khalil, Ashraf / Rimoldi, John M. et al. | 2008
- 3565
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Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescensGouda, Hiroaki / Yanai, Yuichi / Sugawara, Akihiro et al. | 2008
- 3580
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Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzymeShin, Eui Seok / Park, Jiyoung / Shin, Jae-Min et al. | 2008
- 3587
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Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: Introducing a diketoacid functionality into delavirdineWang, Zhengqiang / Vince, Robert et al. | 2008
- 3596
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Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase AWang, Si-Hong / Wang, Shou-Feng / Xuan, Wei et al. | 2008
- 3602
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N-Aroyl-3,5-bis(benzylidene)-4-piperidones: A novel class of antimycobacterial agentsDas, Umashankar / Das, Swagatika / Bandy, Brian et al. | 2008
- 3608
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Synthesis of curcumin mimics with multidrug resistance reversal activitiesUm, Yumi / Cho, Sungsik / Woo, Ho Bum et al. | 2008
- 3616
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In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modification of biliverdinBulmer, Andrew C. / Blanchfield, Joanne T. / Coombes, Jeff. S. et al. | 2008
- 3626
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Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell linesKok, Stanton Hon Lung / Gambari, Roberto / Chui, Chung Hin et al. | 2008
- 3632
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Synthesis and antifungal activity of novel sulfoxide derivatives containing trimethoxyphenyl substituted 1,3,4-thiadiazole and 1,3,4-oxadiazole moietyLiu, Fang / Luo, Xiao-Qiong / Song, Bao-An et al. | 2008
- 3641
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Antioxidant and cytotoxic activities of canadine: Biological effects and structural aspectsCorreché, Estela R. / Andujar, Sebastian A. / Kurdelas, Rita R. et al. | 2008
- 3652
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Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylationWiemer, Andrew J. / Yu, Jose S. / Shull, Larry W. et al. | 2008
- 3661
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Synthesis, antimalarial activity, structure–activity relationship analysis of thieno-[3,2-b]benzothiazine S,S-dioxide analogsBarazarte, Arthur / Camacho, José / Domínguez, José et al. | 2008
- 3675
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CoMFA and HQSAR studies on 6,7-dimethoxy-4-pyrrolidylquinazoline derivatives as phosphodiesterase10A inhibitorsKulkarni, Shridhar S. / Patel, Maulik R. / Talele, Tanaji T. et al. | 2008
- 3687
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Studies on quinones. Part 43: Synthesis and cytotoxic evaluation of polyoxyethylene-containing 1,4-naphthoquinonesValderrama, Jaime A. / Leiva, Hilda / Rodríguez, Jaime A. et al. | 2008
- 3694
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Methoxylation of 3prime,4prime-aromatic side chains improves P-glycoprotein inhibitory and multidrug resistance reversal activities of 7,8-pyranocoumarin against cancer cellsFong, W. F. / Shen, X. L. / Globisch, C. et al. | 2008
- 3694
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Methoxylation of 3′,4′-aromatic side chains improves P-glycoprotein inhibitory and multidrug resistance reversal activities of 7,8-pyranocoumarin against cancer cellsFong, Wang-Fun / Shen, Xiao-Ling / Globisch, Christoph et al. | 2008
- 3704
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Platinum(II) complexes with steroidal esters of l-methionine and l-histidine: Synthesis, characterization and cytotoxic activityKvasnica, Miroslav / Budesinsky, Milos / Swaczynova, Jana et al. | 2008
- 3714
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2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: Synthesis and structure–activity relationshipVicini, Paola / Geronikaki, Athina / Incerti, Matteo et al. | 2008
- 3725
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A novel sesquiterpene lactone from Centaurea pullata: Structure elucidation, antimicrobial activity, and prediction of pharmacokinetic propertiesDjeddi, Samah / Karioti, Anastasia / Sokovic, Marina et al. | 2008
- 3732
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4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulatorsColabufo, Nicola Antonio / Berardi, Francesco / Cantore, Mariangela et al. | 2008
- 3744
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Synthesis and evaluation of homodimeric GnRHR antagonists having a rigid bis-propargylated benzene coreBonger, Kimberly M. / van den Berg, Richard J.B.H.N. / Knijnenburg, Annemiek D. et al. | 2008
- 3759
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Selective plasma protein binding of antimalarial drugs to α1-acid glycoproteinZsila, Ferenc / Visy, Júlia / Mády, György et al. | 2008
- 3759
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Selective plasma protein binding of antimalarial drugs to a1-acid glycoproteinZsila, F. / Visy, J. / Mady, G. et al. | 2008
- 3773
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Synthesis and neuropharmacological evaluation of 2-aryl- and alkylapomorphinesSipos, Attila / Kiss, Béla / Schmidt, Éva et al. | 2008
- 3780
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g-Carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activitySako, K. / Aoyama, H. / Sato, S. et al. | 2008
- 3780
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γ-Carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activitySako, Kumiko / Aoyama, Hiroshi / Sato, Shinichi et al. | 2008
- 3791
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Ester derivatives of gallic acid with potential toxicity toward L1210 leukemia cellsLocatelli, Claudriana / Rosso, Rober / Santos-Silva, Maria C. et al. | 2008
- 3800
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Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARαMizuno, Cassia S. / Ma, Guoyi / Khan, Shabana et al. | 2008
- 3800
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Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARaMizuno, C. S. / Ma, G. / Khan, S. et al. | 2008
- 3809
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Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-l-homocysteine hydrolaseAndo, Takayuki / Iwata, Masafumi / Zulfiqar, Fazila et al. | 2008
- 3816
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The synthesis of 5-substituted ring E analogs of methyllycaconitine via the Suzuki–Miyaura cross-coupling reactionHuang, Junfeng / Orac, Crina M. / McKay, Susan et al. | 2008
- 3825
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Synthesis of eudistomin D analogues and its effects on adenosine receptorsIshiyama, Haruaki / Ohshita, Kengo / Abe, Tetsuro et al. | 2008
- 3831
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Synthesis and GABAA receptor activity of oxygen-bridged neurosteroid analogsAlvarez, Lautaro D. / Veleiro, Adriana S. / Baggio, Ricardo F. et al. | 2008
- 3839
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Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitorsZhang, Jie / Wang, Qiang / Fang, Hao et al. | 2008
- 3848
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Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activityZhu, Zhengxiang / Buolamwini, John K. et al. | 2008
- 3866
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Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylaseHatano, Akihiko / Harano, Aiko / Takigawa, Yoshikatsu et al. | 2008
- 3871
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Synthesis, DNA binding and cleavage activities of the copper (II) complexes of estrogen-macrocyclic polyamine conjugatesYang, Xin-Bin / Feng, Jie / Zhang, Ji et al. | 2008
- 3878
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A spectroscopy approach for the study of the interactions of bioactive vanadium species with bovine serum albuminFerrer, Evelina G. / Bosch, Alejandra / Yantorno, Osvaldo et al. | 2008
- 3887
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Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitorsWang, Yue-Ping / Chen, Fen-Er / De Clercq, Erik et al. | 2008
- 3895
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Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicityKamal, Ahmed / Kumar, P. Praveen / Seshadri, B.N. et al. | 2008
- 3907
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Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitorsReddy, M.V. Ramana / Billa, Vinay K. / Pallela, Venkat R. et al. | 2008
- 3917
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Discovery of potent cholecystokinin-2 receptor antagonists: Elucidation of key pharmacophore elements by X-ray crystallographic and NMR conformational analysisRosen, Mark D. / Hack, Michael D. / Allison, Brett D. et al. | 2008
- 3926
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Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitorsAlexiou, Polyxeni / Nicolaou, Ioannis / Stefek, Milan et al. | 2008
- 3933
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Carbonic anhydrase inhibitors: Inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamidesSączewski, Franciszek / Innocenti, Alessio / Sławiński, Jarosław et al. | 2008
- 3941
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Novel cyclohexene derivatives as anti-sepsis agents: Synthetic studies and inhibition of NO and cytokine productionYamada, Masami / Ichikawa, Takashi / Ii, Masayuki et al. | 2008
- 3959
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The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compoundsHasinoff, Brian B. / Liang, Hong / Wu, Xing et al. | 2008
- 3969
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Structure–activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effectsTakasawa, Ryoko / Takahashi, Saki / Saeki, Kazunori et al. | 2008
- 3976
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Cytotoxic activity of proflavine diureas: Synthesis, antitumor, evaluation and DNA binding properties of 1prime,1Prime-(acridin-3,6-diyl)-3prime,3Prime-dialkyldiureasKozurkova, M. / Sabolova, D. / Janovec, L. et al. | 2008
- 3976
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Cytotoxic activity of proflavine diureas: Synthesis, antitumor, evaluation and DNA binding properties of 1′,1″-(acridin-3,6-diyl)-3′,3″-dialkyldiureasKožurková, Mária / Sabolová, Danica / Janovec, Ladislav et al. | 2008
- 3985
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Novel 16-membered macrolides modified at C-12 and C-13 positions of midecamycin A1 and miokamycin. Part 1: Synthesis and evaluation of 12,13-carbamate and 12-arylalkylamino-13-hydroxy analoguesMiura, Tomoaki / Kurihara, Ken-ichi / Furuuchi, Takeshi et al. | 2008
- 4003
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A single thiourea group is not enough to get stable thiourea lipoplexesKabha, Eihab / Jacquement, Claire / Pembouong, Gaëlle et al. | 2008
- 4009
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Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanonesSerra, H. / Mendes, T. / Bronze, M.R. et al. | 2008
- 4019
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A class of novel nitronyl nitroxide labeling basic and acidic amino acids: Synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigationsZhang, Jianwei / Zhao, Ming / Cui, Guohui et al. | 2008
- 4029
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DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy·dGWeledji, Yvonne N. / Wiederholt, Carissa J. / Delaney, Michael O. et al. | 2008
- 4035
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Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligandsSong, Kwang-Seop / Lee, Sung-Han / Chun, Hyun Ji et al. | 2008
- 4052
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A structural analysis of the differential cytotoxicity of chemicals in the NCI-60 cancer cell linesChakravarti, Suman K. / Klopman, Gilles et al. | 2008
- 4064
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Modeling and synthesis of novel tight-binding inhibitors of cytochrome P450 2C9Peng, Chi-Chi / Rushmore, Tom / Crouch, Gregory J. et al. | 2008
- 4075
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Synthesis, structure and antibacterial activity of novel 1-(5-substituted-3-substituted-4,5-dihydropyrazol-1-yl)ethanone oxime ester derivativesLiu, Xin-Hua / Cui, Pin / Song, Bao-An et al. | 2008
- 4083
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Alkyl deoxy-arabino-hexopyranosides: Synthesis, surface properties, and biological activitiesSilva, Filipa V.M. / Goulart, Margarida / Justino, Jorge et al. | 2008
- 4093
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Synthesis and structure–activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitorsFukushima, Hiroshi / Hiratate, Akira / Takahashi, Masato et al. | 2008
- 4107
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A binary QSAR model for classification of hERG potassium channel blockersThai, Khac-Minh / Ecker, Gerhard F. et al. | 2008
- 4120
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Bioactive alkenylphenols from Piper obliquumValdivia, Carola / Marquez, Nieves / Eriksson, John et al. | 2008
- 4127
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Design and synthesis of cyclic disulfide-bonded antibacterial peptides on the basis of the α helical domain of Tenecin 1, an insect defensinAhn, Hye-sun / Cho, Wonmi / Kim, Joung-min et al. | 2008
- 4127
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Design and synthesis of cyclic disulfide-bonded antibacterial peptides on the basis of the a helical domain of Tenecin 1, an insect defensinAhn, H. s. / Cho, W. / Kim, J. m. et al. | 2008
- 4138
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Structure-based virtual screening against SARS-3CLpro to identify novel non-peptidic hitsMukherjee, Prasenjit / Desai, Prashant / Ross, Larry et al. | 2008
- 4150
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Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activityFortuna, Cosimo Gianluca / Barresi, Vincenza / Berellini, Giuliano et al. | 2007
- 4160
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Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure–activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamatesCesarini, Sara / Spallarossa, Andrea / Ranise, Angelo et al. | 2007
- 4173
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Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Parallel synthesis, molecular modelling and structure–activity relationship studies on analogues of O-(2-phenylethyl)-N-phenylthiocarbamateCesarini, Sara / Spallarossa, Andrea / Ranise, Angelo et al. | 2007
- 4186
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Erratum to “Novel analogs of d-e-MAPP and B13. Part 1: Synthesis and evaluation as potential anticancer agents” [Bioorg. Med. Chem. 16 (2008) 1015–1031]Szulc, Zdzislaw M. / Mayroo, Nalini / Bai, AiPing et al. | 2008
- 4187
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Erratum to “Novel analogs of d-e-MAPP and B13. Part 2: Signature effects on bioactive sphingolipids” [Bioorg. Med. Chem. 16 (2008) 1032–1045]Bielawska, Alicja / Bielawski, Jacek / Szulc, Zdzislaw M. et al. | 2008
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Instructions to contributors| 2008
- IFC
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Editorial board| 2008