Synthesis and anti-tumor evaluation of panaxadiol halogen-derivatives (English)
- New search for: Xiao, Shengnan
- New search for: Chen, Shuai
- New search for: Sun, Yuanyuan
- New search for: Zhou, Wuxi
- New search for: Piao, Huri
- New search for: Zhao, Yuqing
- New search for: Xiao, Shengnan
- New search for: Chen, Shuai
- New search for: Sun, Yuanyuan
- New search for: Zhou, Wuxi
- New search for: Piao, Huri
- New search for: Zhao, Yuqing
In:
Bioorganic & medicinal chemistry letters
;
27
, 17
;
4204-4211
;
2017
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ISSN:
- Article (Journal) / Print
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Title:Synthesis and anti-tumor evaluation of panaxadiol halogen-derivatives
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Contributors:Xiao, Shengnan ( author ) / Chen, Shuai ( author ) / Sun, Yuanyuan ( author ) / Zhou, Wuxi ( author ) / Piao, Huri ( author ) / Zhao, Yuqing ( author )
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Published in:Bioorganic & medicinal chemistry letters ; 27, 17 ; 4204-4211
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Publisher:
- New search for: Elsevier Science B.V., Amsterdam.
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Publication date:2017-01-01
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Size:8 pages
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ISSN:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 572
- Further information on Dewey Decimal Classification
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Classification:
DDC: 572 -
Source:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents – Volume 27, Issue 17
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 3945
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Lead selection of antiparasitic compounds from a focused library of benzenesulfonyl derivatives of heterocyclesPagliero, Romina J. / Kaiser, Marcel / Brun, Reto / Nieto, Marcelo J. / Mazzieri, María R. et al. | 2017
- 3950
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Development of helix-stabilized antimicrobial peptides composed of lysine and hydrophobic α,α-disubstituted α-amino acid residuesMisawa, Takashi / Imamura, Mitsuyoshi / Ozawa, Yuto / Haishima, Kazuchika / Kurihara, Masaaki / Kikuchi, Yutaka / Demizu, Yosuke et al. | 2017
- 3954
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Design, synthesis and antiproliferative activity of novel substituted 2-amino-7,8-dihydropteridin-6(5H)-one derivativesLi, Qiu / Yang, Hai-Kui / Sun, Qi / You, Wen-Wei / Zhao, Pei-Liang et al. | 2017
- 3959
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Design, synthesis, and cytotoxic activity of novel 7-substituted camptothecin derivatives incorporating piperazinyl-sulfonylamidine moietiesYang, Cheng-Jie / Song, Zi-Long / Goto, Masuo / Liu, Ying-Qian / Hsieh, Kan-Yen / Morris-Natschke, Susan L. / Zhao, Yong-Long / Zhang, Jun-Xiang / Lee, Kuo-Hsiung et al. | 2017
- 3963
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Imidazo[1,2-α]pyridines possess adenosine A1 receptor affinity for the potential treatment of cognition in neurological disordersLefin, Roslyn / van der Walt, Mietha M. / Milne, Pieter J. / Terre'Blanche, Gisella et al. | 2017
- 3968
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Beneficial effects of a medicinal herb, Cirsium japonicum var. maackii, extract and its major component, cirsimaritin on breast cancer metastasis in MDA-MB-231 breast cancer cellsYeon Park, Jun / Young Kim, Hyun / Shibamoto, Takayuki / Su Jang, Tae / Cheon Lee, Sang / Suk Shim, Jae / Hahm, Dae-Hyun / Lee, Hae-Jeung / Lee, Sanghyun / Sung Kang, Ki et al. | 2017
- 3974
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Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studiesSingh, Harbinder / Singh, Jatinder V. / Gupta, Manish K. / Saxena, Ajit K. / Sharma, Sahil / Nepali, Kunal / Bedi, Preet Mohinder S. et al. | 2017
- 3980
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Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibitionTavani, Cinzia / Bianchi, Lara / De Palma, Annalisa / Passeri, Giovanna Ilaria / Punzi, Giuseppe / Pierri, Ciro Leonardo / Lovece, Angelo / Cavalluzzi, Maria Maddalena / Franchini, Carlo / Lentini, Giovanni et al. | 2017
- 3987
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2-N-Arylthiazole inhibitors of Mycobacterium tuberculosisClark, Michael P. / Wang, Tiansheng / Perola, Emanuele / Deininger, David D. / Zuccola, Harmon J. / Jones, Steven M. / Gao, Hong / VanderVen, Brian C. / Russell, David G. / Shoen, Carolyn M. et al. | 2017
- 3992
-
Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanismsSiddiqui-Jain, Adam / Hoj, Jacob P. / Hargiss, J. Blade / Hoj, Taylor H. / Payne, Carter J. / Ritchie, Collin A. / Herron, Steven R. / Quinn, Colette / Schuler, Jeffrey T. / Hansen, Marc D.H. et al. | 2017
- 4001
-
Novel anti-prostate cancer scaffold identified by the combination of in silico and cell-based assays targeting the PI3K-AKT-mTOR pathwaySaidel, Marta Érica / dos Santos, Karen C. / Nagano, Luís F.P. / Montanari, Carlos Alberto / Leitão, Andrei et al. | 2017
- 4007
-
Achyrodimer F, a tyrosyl-DNA phosphodiesterase I inhibitor from an Australian fungus of the family CortinariaceaeTian, Li-Wen / Feng, Yunjiang / Tran, Trong D. / Shimizu, Yoko / Pfeifer, Tom / Vu, Hoan T. / Quinn, Ronald J. et al. | 2017
- 4011
-
Synthesis and evaluation of vitamin D3 analogues with C-11 modifications as inhibitors of Hedgehog signalingMaschinot, Chad A. / Hadden, M. Kyle et al. | 2017
- 4015
-
Development of a highly reliable assay for ubiquitin-specific protease 2 inhibitorsWang, Zhongli / Xie, Wenjuan / Zhu, Mingyan / Zhou, Huchen et al. | 2017
- 4019
-
Functionalization of peptide nucleolipid bioconjugates and their structure anti-cancer activity relationship studiesRana, Niki / Cultrara, Christopher / Phillips, Mariana / Sabatino, David et al. | 2017
- 4024
-
Efficient near infrared fluorescence detection of elastase enzyme using peptide-bound unsymmetrical squaraine dyeSaikiran, Maryala / Sato, Daisuke / Pandey, Shyam S. / Hayase, Shuzi / Kato, Tamaki et al. | 2017
- 4030
-
Design and synthesis of iodocarborane-containing ligands with high affinity and selectivity toward ERβOhta, Kiminori / Ogawa, Takumi / Endo, Yasuyuki et al. | 2017
- 4034
-
Discovery of 5-substituent-N-arylbenzamide derivatives as potent, selective and orally bioavailable LRRK2 inhibitorsDing, Xiao / Dai, Xuedong / Long, Kai / Peng, Cheng / Andreotti, Daniele / Bamborough, Paul / Eatherton, Andrew J. / Edge, Colin / Jandu, Karamjit S. / Nichols, Paula L. et al. | 2017
- 4039
-
Iodine-catalyzed Csp3-H functionalization of methylhetarenes: One-pot synthesis and cytotoxic evaluation of heteroarenyl-benzimidazoles and benzothiazoleBaig, Mirza Feroz / Shaik, Siddiq Pasha / Nayak, V. Lakshma / Alarifi, Abdullah / Kamal, Ahmed et al. | 2017
- 4044
-
Discovery of novel pyrazolo[1,5-a]pyridine-based EP1 receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationshipsNishigaya, Yosuke / Umei, Kentaro / Saito, Yoshifumi / Watanabe, Hiroyuki / Kondo, Tatsuhiro / Kondo, Atsushi / Kawamura, Naohiro / Tatani, Kazuya / Kohno, Yasushi / Tanaka, Nobuyuki et al. | 2017
- 4051
-
Structure-based design, synthesis and in vitro antiproliferative effects studies of novel dual BRD4/HDAC inhibitorsShao, Mingfeng / He, Linhong / Zheng, Li / Huang, Lingxiao / Zhou, Yuanyuan / Wang, Taijing / Chen, Yong / Shen, Mingsheng / Wang, Fang / Yang, Zhuang et al. | 2017
- 4056
-
Macrocyclic factor XIa inhibitorsWang, Cailan / Corte, James R. / Rossi, Karen A. / Bozarth, Jeffrey M. / Wu, Yiming / Sheriff, Steven / Myers, Joseph E. Jr. / Luettgen, Joseph M. / Seiffert, Dietmar A. / Wexler, Ruth R. et al. | 2017
- 4061
-
Design, synthesis and evaluation of 2,2-dimethyl-1,3-dioxolane derivatives as human rhinovirus 3C protease inhibitorsZhang, Qiyan / Cao, Ruiyuan / Liu, An / Lei, Shihai / Li, Yuexiang / Yang, Jingjing / Li, Song / Xiao, Junhai et al. | 2017
- 4066
-
Design and synthesis of piperazine acetate podophyllotoxin ester derivatives targeting tubulin depolymerization as new anticancer agentsSun, Wen-Xue / Ji, Ya-Jing / Wan, Yun / Han, Hong-Wei / Lin, Hong-Yan / Lu, Gui-Hua / Qi, Jin-Liang / Wang, Xiao-Ming / Yang, Yong-Hua et al. | 2017
- 4075
-
Design, synthesis and biological evaluation of Lenalidomide derivatives as tumor angiogenesis inhibitorHu, Shengquan / Yuan, Libin / Yan, Hong / Li, Zhigang et al. | 2017
- 4082
-
ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4ATillotson, Joseph / Kedzior, Magdalena / Guimarães, Larissa / Ross, Alison B. / Peters, Tara L. / Ambrose, Andrew J. / Schmidlin, Cody J. / Zhang, Donna D. / Costa-Lotufo, Letícia V. / Rodríguez, Abimael D. et al. | 2017
- 4086
-
Direct observation of positive supercoils introduced by reverse gyrase through atomic force microscopyLi, Dawei / Lv, Bei / wang, Qiang / Liu, Yun / Zhuge, Qiang et al. | 2017
- 4091
-
Synthesis of antimalarial amide analogues based on the plant serrulatane diterpenoid 3,7,8-trihydroxyserrulat-14-en-19-oic acidKumar, Rohitesh / Duffy, Sandra / Avery, Vicky M. / Davis, Rohan A. et al. | 2017
- 4096
-
Synthesis, antiviral activity, and molecular docking study of trans-ferulic acid derivatives containing acylhydrazone moietyWang, Zhenzhen / Xie, Dandan / Gan, Xiuhai / Zeng, Song / Zhang, Awei / Yin, Limin / Song, Baoan / Jin, Linhong / Hu, Deyu et al. | 2017
- 4101
-
Synthesis and evaluation of modified chalcone based p53 stabilizing agentsIftikhar, Sunniya / Khan, Sardraz / Bilal, Aishah / Manzoor, Safia / Abdullah, Muhammad / Emwas, Abdel-Hamid / Sioud, Salim / Gao, Xin / Chotana, Ghayoor Abbas / Faisal, Amir et al. | 2017
- 4107
-
Interplay between H6PDH and 11β-HSD1 implicated in the pathogenesis of type 2 diabetes mellitusYao, Fan / Chen, Li / Fan, Zheng / Teng, Fei / Zhao, Yali / Guan, Fengying / Zhang, Ming / Liu, Yanjun et al. | 2017
- 4114
-
Radiosynthesis and evaluation of new PET ligands for peripheral cannabinoid receptor type 1 imagingYamasaki, Tomoteru / Fujinaga, Masayuki / Shimoda, Yoko / Mori, Wakana / Zhang, Yiding / Wakizaka, Hidekatsu / Ogawa, Masanao / Zhang, Ming-Rong et al. | 2017
- 4118
-
N-alkyl-[1,1′-biphenyl]-2-sulfonamide derivatives as novel broad spectrum anti-epileptic drugs with efficacy equivalent to that of sodium valproateTanaka, Tomoyuki / Yajima, Nana / Kiyoshi, Tomoko / Miura, Yoshiki / Iwama, Seiji et al. | 2017
- 4122
-
Chemical constituents from the rare mushroom Calvatia nipponica inhibit the promotion of angiogenesis in HUVECsLee, Seulah / Park, Jun Yeon / Lee, Dahae / Seok, Soonja / Kwon, Yeon Jung / Jang, Tae Su / Kang, Ki Sung / Kim, Ki Hyun et al. | 2017
- 4128
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Design, synthesis and in vitro anticancer activity of novel quinoline and oxadiazole derivatives of ursolic acidGu, Wen / Jin, Xiao-Yan / Li, Dong-Dong / Wang, Shi-Fa / Tao, Xu-Bing / Chen, Hao et al. | 2017
- 4133
-
Pocket detection and interaction-weighted ligand-similarity search yields novel high-affinity binders for Myocilin-OLF, a protein implicated in glaucomaSrinivasan, Bharath / Tonddast-Navaei, Sam / Skolnick, Jeffrey et al. | 2017
- 4140
-
Design, synthesis and anticancer activity of N-(1-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)-1-oxo-3-phenylpropan-2-yl derivativesGudisela, Mura Reddy / Srinivasu, N. / Mulakayala, Chaitanya / Bommu, Praveen / Rao, M.V. Basaveswara / Mulakayala, Naveen et al. | 2017
- 4146
-
Neuropathic pain-alleviating effects of pyrazole-conjugated arylsulfonamides as 5-HT6 receptor antagonistsHong, Jin Ri / Choo, Hyunah / Nam, Ghilsoo et al. | 2017
- 4150
-
Design, synthesis and biological evaluation of indole derivatives as Vif inhibitorsPu, Chunlan / Luo, Rong-Hua / Zhang, Mengqi / Hou, Xueyan / Yan, Guoyi / Luo, Jiang / Zheng, Yong-Tang / Li, Rui et al. | 2017
- 4156
-
Design, synthesis, docking and biological evaluation of 4-phenyl-thiazole derivatives as autotaxin (ATX) inhibitorsBalupuri, Anand / Lee, Dae-Yon / Lee, Myeong Hwi / Chae, Sangeun / Jung, Eunmi / Kim, Yunki / Ryu, Jeonghee / Kang, Nam Sook et al. | 2017
- 4165
-
The hydrolytic susceptibility of prochelator BSIH in aqueous solutionsWang, Qin / Franz, Katherine J. et al. | 2017
- 4171
-
Discovery of (R)-5-(benzo[d][1,3]dioxol-5-yl)-7-((1-(vinylsulfonyl)pyrrolidin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (B6) as a potent Bmx inhibitor for the treatment of NSCLCHe, Linhong / Li, Da / Zhang, Chufeng / Bai, Peng / Chen, Lijuan et al. | 2017
- 4176
-
Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptorYamamoto, Naoshi / Ohrui, Sayaka / Okada, Takahiro / Yata, Masahiro / Saitoh, Tsuyoshi / Kutsumura, Noriki / Nagumo, Yasuyuki / Irukayama-Tomobe, Yoko / Ogawa, Yasuhiro / Ishikawa, Yukiko et al. | 2017
- 4180
-
Design, synthesis and biological evaluation of dual acetylcholinesterase and phosphodiesterase 5A inhibitors in treatment for Alzheimer’s diseaseZhou, Li-yun / Zhu, Yao / Jiang, Yu-ren / Zhao, Xiong-jie / Guo, Dong et al. | 2017
- 4185
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Discovery of novel 4(1H)-quinolone derivatives as potential antiproliferative and apoptosis inducing agentsZhou, Ping / Huang, Linsheng / Zhou, Jie / Jiang, Bin / Zhao, Yanmei / Deng, Xuehua / Zhao, Qin / Li, Fei et al. | 2017
- 4190
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Effects of novel triple-stage antimalarial ionic liquids on lipid membrane modelsFerraz, Ricardo / Pinheiro, Marina / Gomes, Ana / Teixeira, Cátia / Prudêncio, Cristina / Reis, Salette / Gomes, Paula et al. | 2017
- 4194
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Discovery of orally bioavailable cyclohexanol-based NR2B-selective NMDA receptor antagonists with analgesic activity utilizing a scaffold hopping approachAnan, Kosuke / Masui, Moriyasu / Hara, Shinichiro / Ohara, Miho / Kume, Masaharu / Yamamoto, Shoichi / Shinohara, Shunji / Tsuji, Hiroki / Shimada, Shinji / Yagi, Shigenori et al. | 2017
- 4199
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Syntheses of cytotoxic novel arctigenin derivatives bearing halogen and alkyl groups on aromatic ringsYamauchi, Satoshi / Wukirsari, Tuti / Ochi, Yoshiaki / Nishiwaki, Hisashi / Nishi, Kosuke / Sugahara, Takuya / Akiyama, Koichi / Kishida, Taro et al. | 2017
- 4204
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Synthesis and anti-tumor evaluation of panaxadiol halogen-derivativesXiao, Shengnan / Chen, Shuai / Sun, Yuanyuan / Zhou, Wuxi / Piao, Huri / Zhao, Yuqing et al. | 2017
- 4212
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Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonistsLao, Kejing / Sun, Jie / Wang, Chong / Wang, Ying / You, Qidong / Xiao, Hong / Xiang, Hua et al. | 2017
- 4218
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Corrigendum to ‘Easy and rapid preparation of benzoylhydrazides and their diazene derivatives as inhibitors of 15-lipoxygenase’ [Bioorg. Med. Chem. Lett. 27 (2017) 1649–1653]Tirapegui, Cristian / Acevedo-Fuentes, Williams / Dahech, Pablo / Torrent, Claudia / Barrias, Pablo / Rojas-Poblete, Macarena / Mascayano, Carolina et al. | 2017
- IFC
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Editorial board| 2017