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Experimental investigations for a 96 day period into the effect of a mixture of gases with an aerosol in SO2 concentrations of 0.05 mg/cu m, CO 1 mg/cu m, phenol 0.01 mg/cu m and dust 0.15 mg/cu m showed significant changes in all tests used for the animals. The total of the combinations of fractional concentrations of substances from their threshold (concentrations) at a level of 0.76 proved to be inoperative. The combined resorptive effect of small concentrations of sulfur dioxide, carbon monoxide, phenol, and dust is characteristic of the effect of summation. To evaluate the degree to which atmospheric air is polluted with around the clock sampling it can be recommended that the level at which the sum of the fractions of concentrations from their maximum permissible amounts not exceed 0.76.