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Americans are traveling more and, in the view of many observers, enjoying it less. Modern jet travel, along with the necessity or desire to see as many tourist sights or conduct as many business meetings as possible in a single day, serve to create a well-defined but often overlooked symptom complex called travel stress. Travel stress is the complex interaction of a number of environmental, physiological, and psychological stressors. Disruptions in the traveler's circadian rhythm, changes in dietary habits, noise, vibration, pattern changes in the use of stimulants and alcohol, and the pressure of trying to get the most for one's travel dollar impact the health and efficiency of the traveler. This paper outlines proven and practical pre-travel prevention techniques and en route therapy. (Author)