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How does this end? Increasingly, this question is dominating discussion of the Russia-Ukraine war in Washington and other Western capitals. Although successful Ukrainian counteroffensives in Kharkiv and Kherson in fall 2022 renewed optimism about Kyiv's prospects on the battlefield, Russian President Vladimir Putin's announcement on September 21 of a partial mobilization and annexation of four Ukrainian provinces was a stark reminder that this war is nowhere near a resolution. Fighting still rages across nearly 1,000 km of front lines. Negotiations on ending the conflict have been suspended since May. The trajectory and ultimate outcome of the war will, of course, be determined largely by the policies of Ukraine and Russia. But Kyiv and Moscow are not the only capitals with a stake in what happens. This war is the most significant interstate conflict in decades, and its evolution will have major consequences for the United States. It is appropriate to assess how this conflict may evolve, what alternative trajectories might mean for U.S. interests, and what Washington can do to promote a trajectory that best serves U.S. interests.