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Severe bone loss commonly occurs in individuals with chronic spinal cord injury who are non-weightbearing and leads to an increased risk of lower extremity fractures. This multi-site, double-blind, randomized, placebo- controlled study evaluates the efficacy and safety of two interventions known to be anabolic to bone, parathyroid hormone and mechanical loading (provided as teriparatide and vibration) in 60 SCI individuals with low bone mass. After the first year of this project, all clinical sites have obtained regulatory approval and all preparatory work has been completed. Five participants have been enrolled with 4 additional participants in the run-in phase of the study. No results regarding efficacy or safety of these interventions are yet available.