Most unmanned aircraft systems will be required to be equipped with a Detect-and-Avoid (DAA) system. The surveillance performance of the DAA system to detect and track intruder aircraft will depend on the encounter geometries that unmanned aircraft are expected to have with other aircraft in the airspace. The performance of DAA alerting and avoidance system is also dependent on the timeliness of alerting for UAS pilots to give a sufficient time to determine and command a resolution maneuver to avoid well clear separation violations. This presentation introduces general background of UAS DAA systems and concept of well clear separation standard to satisfy see and avoid regulations. The presentation shows the several UAS mission profiles and analysis of the encounter geometries that were simulated using historical VFR traffic data and some proposed UAS missions. This presentation introduces several potential metrics for evaluating the performance of a DAA system and shows the results that measured through fast-time simulation with traffic scenarios that include NAS-wide VFR manned aircraft and IFR UAS flights. At the end, some research areas will be briefly discussed.