High-cycle fatigue (HCF) behavior of a melt-infiltrated, prepreg SiC/SiC composite was investigated using specimens without and with simulated cooling holes at 816 and 1,316 °C. The ceramic-matrix composite (CMC) material used for this study was fabricated by GE Aviation and had a ply configuration of [0/90/0]3. HCF tests were conducted with an R-ratio of 0.6 and a cyclic frequency of 30 Hz. Maximum tensile gross-section stresses used in the HCF tests ranged from 152 to 359 MPa. Runout in HCF was defined as 30 million cycles (278 h) at both temperatures. Monotonic tensile tests were conducted at room temperature (RT) on as-received CMC specimens and on HCF runout specimens without and with holes to determine residual tensile strengths. Digital image correlation (DIC) and acoustic emission (AE) techniques were used to monitor progression of damage in RT tensile tests on specimens without and with holes. Fractography was performed on a limited number of specimens without and with holes to determine morphology of fracture surfaces. Representative RT stress-strain behavior, elevated temperature HCF behavior at the two temperatures, and RT residual tensile strengths of HCF runout specimens are documented in this report. Select examples of DIC and AE data from RT tensile tests on specimens without and with holes and typical features observed on fracture surfaces of specimens tested under tensile and HCF conditions are also discussed.