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Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor Signalling
Karger Verlag | 2017|Keywords: FXR antagonism, FXR agonism -
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
Free accessBASE | 2016|Keywords: FXR, selective FXR agonists -
Discovery and SAR study of 3-(tert-butyl)-4-hydroxyphenyl benzoate and benzamide derivatives as novel farnesoid X receptor (FXR) antagonists
Elsevier | 2015|Keywords: FXR, FXR antagonist -
Prevention of spontaneous hepatocarcinogenesis in FXR null mice by intestinal specific FXR re-activation.
Free accessBASE | 2015|Keywords: Farnesoid X receptor (FXR) -
Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet
Elsevier | 2011|Keywords: FXR -
NR1H4 rs35724 G>C variant modulates liver damage in nonalcoholic fatty liver disease
Wiley | 2021|Keywords: FXR -
Role of FXR in Bile Acid and Metabolic Homeostasis in NASH: Pathogenetic Concepts and Therapeutic Opportunities
Free accessThieme Verlag | 2021|Keywords: FXR -
Promotion of lipogenesis by PPARγ-activated FXR expression in adipocytes
Elsevier | 2020|Keywords: FXR -
Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists
Elsevier | 2014|Keywords: FXR agonist -
Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties
Elsevier | 2015|Keywords: FXR agonists, Fluorescent FXR ligand -
Transcriptional Regulation of Human UDP-Glucuronosyltransferase 2B10 by Farnesoid X Receptor in Human Hepatoma HepG2 Cells
American Chemical Society | 2017|Keywords: FXR -
Altered enterohepatic circulation of bile acids in Crohn’s disease and their clinical significance: a new perspective
Taylor & Francis Verlag | 2013|Keywords: FXR, FXR agonists -
Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation
Free accessWiley | 2019|Keywords: FXR -
Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist
Elsevier | 2007|Keywords: FXR, FXR antagonist -
Novel stereoselective synthesis and chromatographic evaluation of E-guggulsterone
Elsevier | 2011|Keywords: FXR
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