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Synonyms were used for: Molekülphysik
Search without synonyms: keywords:(Molekülphysik)
Used synonyms:
- molecular physics
- molecules
- molekularphysik
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G-Protein-Coupled Receptor Trafficking: Understanding the Chemical Basis of Health and Disease
American Chemical Society | 2006|Keywords: Mutant receptors: Protein molecules with an altered amino acid sequence due to changes in the nucleotide sequence of their corresponding gene., Pharmacological chaperones: Low-molecularweight molecules that enter cells and are templates for correcting misfolded mutants. -
Small-Molecule Screening: Advances in Microarraying and Cell-Imaging Technologies
American Chemical Society | 2007|Keywords: Chemical genetics: The use of small molecules to perturb protein and signaling pathways of biological systems., High-throughput screening: Process by which large numbers of small molecules are screened for biological activity rapidly and in parallel., Small-molecule microarray: Array of small molecules immobilized as spatially discrete spots onto a modified glass or gel surface. -
Design and Implementation of Cell-Based Assays To Model Human Disease
American Chemical Society | 2007|Keywords: Library choice: The selection of collections of small molecules for use in high-throughput screens., High-throughput screening: The utilization of an enzymatic, biochemical, or a cell-based assay to evaluate hundreds or thousands of small molecules or genes in parallel. -
A Survey of Single-Molecule Techniques in Chemical Biology
American Chemical Society | 2007|Keywords: Fluorescence resonance energy transfer (FRET): When a fluorescent dye (donor) is excited by a light source, energy can be transferred nonradiatively to another dye (acceptor), which is within ∼2–8 nm. Typically, FRET measurements are performed between two different fluorescent dyes where the emission of the donor dye overlaps the absorption of the acceptor. As the two molecules come closer together, the donor emission decreases in intensity while the acceptor emission increases., Optical tweezers: A technique in which a bead or microsphere is trapped in a laser beam. Molecules can be attached to the trapped bead, which is then immobilized to another bead, a micropipet, or the surface. The beads can then be manipulated so that physical properties, such as force or molecular motions, can be measured. -
Expanding the Nucleotide Repertoire of the Ribosome with Post-Transcriptional Modifications
American Chemical Society | 2007|Keywords: Small nucleolar RNAs: snoRNAs are a class of small noncoding RNA molecules that guide chemical modification (e.g., methylation or pseudouridylation) of eukaryotic rRNAs. -
A TAD Further: Exogenous Control of Gene Activation
American Chemical Society | 2007|Keywords: Activator ATF: An activator ATF up-regulates specific genes or sets of genes by binding to a particular sequence of DNA and interacting with one or more components of the transcriptional machinery. Molecules that indirectly affect gene activation, for example, by stimulating signal transduction cascades or altering DNA structure, are thus not activator ATFs. -
Achieving In-Depth Proteomics Profiling by Mass Spectrometry
American Chemical Society | 2007|Keywords: Electrospray ionization (ESI): A method that ionizes analytes and efficiently transfers nonvolatile biomolecules from solution to the gas phase. Analytes are introduced to the MS inlet at atmospheric pressure via liquid droplets sprayed from a finely drawn needle held at a high potential relative to the inlet. Large electric fields generate charged droplets. Evaporation of solvent from the droplets leads to increased charge density and coulombic repulsion between analytes, driving fission processes that eventually create single, gas-phase analyte molecules. -
Molecular Electron Microscopy: State of the Art and Current Challenges
American Chemical Society | 2008|Keywords: Single particle electron microscopy: A TEM method to study an ensemble of identical molecules (single particles). While images of the individual particles are noisy, by combining thousands of images the signal-to-noise ratio can be improved and a three-dimensional reconstruction can be calculated., Electron crystallography: A TEM method used to study the structure of molecules in a two-dimensional array (2D crystal). In materials sciences this method mostly relies on electron diffraction for data collection, while for 2D crystals of biological molecules typically both images and electron diffraction patterns are recorded, which provide phase and amplitude information, respectively., Molecular electron microscopy: The use of transmission electron microscopy (TEM) to obtain structural information of biological molecules, isolated or in the context of a cell, as opposed to the use of TEM to visualize cellular fine structure. -
Design and Applications of Bifunctional Small Molecules: Why Two Heads Are Better Than One
American Chemical Society | 2008|Keywords: Chemical Inducers of Dimerization (CID): Small molecules that can specifically cause dimerization of two protein molecules. -
Bright Ideas for Chemical Biology
American Chemical Society | 2008|Keywords: Fluorophore: A fluorescent moiety that can consist of disparate chemical structures, including small molecules, proteins, and semiconductor beads -
Building a Parallel Metabolism within the Cell
American Chemical Society | 2008|Keywords: Compartmentalization: A phenomenon used to isolate different molecules within the cell via physical barriers, temporally distinct synthesis, or an absence of molecular interactions. For example, membrane-bound organelles can have different pH, availability of molecular precursors, and enzyme systems. This enables the cell to carry out different metabolic activities without interference. -
Combined Approaches to Site-Specific Modification of RNA
American Chemical Society | 2008|Keywords: Solid-phase synthesis: A method in which molecules are bound to a bead and reacted in a stepwise fashion; the attachment to the bead facilitates removal of excess reagents and byproducts. The order of the reaction is generally controlled by stepwise deprotection of the functional groups on the starting molecule or added groups. -
Sesamin Mitigates Inflammation and Oxidative Stress in Endothelial Cells Exposed to Oxidized Low-Density Lipoprotein
American Chemical Society | 2009|Keywords: adhesion molecules -
Modulation of Akt, JNK, and p38 Activation Is Involved in Citrus Flavonoid-Mediated Cytoprotection of PC12 Cells Challenged by Hydrogen Peroxide
American Chemical Society | 2009|Keywords: signaling molecules -
Panax notoginseng Reduces Atherosclerotic Lesions in ApoE-Deficient Mice and Inhibits TNF-α-Induced Endothelial Adhesion Molecule Expression and Monocyte Adhesion
American Chemical Society | 2009|Keywords: adhesion molecules -
Acteoside and 6-O-Acetylacteoside Downregulate Cell Adhesion Molecules Induced by IL-1β through Inhibition of ERK and JNK in Human Vascular Endothelial Cells
American Chemical Society | 2009|Keywords: cell adhesion molecules -
Olive Oil Phenolic Compounds Inhibit Homocysteine-Induced Endothelial Cell Adhesion Regardless of Their Different Antioxidant Activity
American Chemical Society | 2009|Keywords: Adhesion molecules -
Ribosomal Translocation: One Step Closer to the Molecular Mechanism
American Chemical Society | 2009|Keywords: Ribosomes: Megadalton ribonucleoprotein particles that synthesize protein in all cells and bacterium-derived organelles. The ribosome is composed of three or four large RNA molecules and >50 distinct protein molecules. Each ribosome has two subunits and three tRNA binding sites, aminoacyl (A), peptidyl (P), and exit (E), which lie at the subunit interface. Codons on mRNA are iteratively decoded on the small subunit, while peptidyl transfer occurs on the large subunit. -
Using Small Molecules To Dissect Mechanisms of Microbial Pathogenesis
American Chemical Society | 2009|Keywords: Quorum sensing: A process by which bacteria use secreted small molecules such as N-Acyl Homoserine Lactones (AHLs) to communicate population density., Chemical genetics: The use of highly specific small molecules to determine the function of a gene product of interest. -
Illuminating the Chemistry of Life: Design, Synthesis, and Applications of “Caged” and Related Photoresponsive Compounds
American Chemical Society | 2009|Keywords: Quantum yield (Θ) of uncaging: A measure of the efficiency with which absorbed light converts a caged compound to its uncaged counterpart. Θ is acquired by dividing the number of uncaged molecules produced by the number of photons absorbed. Consequently, by definition, Θ ≤ 1.
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