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Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis
American Chemical Society | 2016| -
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors
American Chemical Society | 2020| -
Discovery and Characterization of (8S,9R)‑5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl‑1H‑1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro‑3H‑pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer Agent
American Chemical Society | 2016| -
The Importance of Being Me: Magic Methyls, Methyltransferase Inhibitors, and the Discovery of Tazemetostat
American Chemical Society | 2016| -
Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival
American Chemical Society | 2016| -
New Frontiers in Selective Human MAO‑B Inhibitors
MiniperspectiveAmerican Chemical Society | 2015| -
Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer
American Chemical Society | 2020| -
Discovery of 2‑Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods
American Chemical Society | 2016| -
Targeting Nucleus DNA with a Cyclometalated Dipyridophenazineruthenium(II) Complex
American Chemical Society | 2014| -
Origins of the Quinolone Class of Antibacterials: An Expanded “Discovery Story”
MiniperspectiveAmerican Chemical Society | 2015| -
Optimization of a Novel Binding Motif to (E)‑3-(3,5-Difluoro-4-((1R,3R)‑2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro‑1H‑pyrido[3,4‑b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist
American Chemical Society | 2015| -
Novel 3‑Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism
American Chemical Society | 2016|
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