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Plant-derived exosomes: a green approach for cancer drug delivery
Royal Society of Chemistry | 2024|limitations of traditional drug delivery tools. Extraction of PDEs from plant sources employ diverse methodologies, encompassing ultracentrifugation ...Publisher: The Royal Society of Chemistry -
Structure-based investigation of pyruvate dehydrogenase kinase-3 inhibitory potential of thymoquinone, targeting lung cancer therapy
Elsevier | 2024|phosphorylation” (OXPHOS) in mitochondria. The pyruvate dehydrogenase kinases (PDKs) have many regulatory roles in energy generation balance by ...Keywords: Drug design and discovery -
Exosome-mediated delivery and regulation in neurological disease progression
Elsevier | 2024|biological sources, have recently seized the attention of researchers due to their theranostic potential for neurological diseases. Released actively ...Keywords: Drug delivery -
Role of Metal-Organic Frameworks (MOFs) in treating and diagnosing microbial infections
Elsevier | 2024|Abstract This review article highlights the innovative role of metal ... -
Epigenetic regulation of hepatocellular carcinoma progression: MicroRNAs as therapeutic, diagnostic and prognostic factors
Elsevier | 2024|regulatory role of miRNAs in HCC extends beyond their immediate function, as they are also influenced by other epigenetic factors like lncRNAs and ... -
Recombinant monoclonal antibody production in yeasts: Challenges and considerations
Elsevier | 2024|for the successful production of recombinant mAbs. However, there are very few yeast-derived mAbs that got the approval of the regulatory ...Keywords: Variable domain of heavy chain, Variable domain of light chain, Constant domain of heavy chain, Constant domain of light chain, United States Food and Drug Administration, Kyoto Encyclopedia of Genes and Genomes, Target-mediated drug deposition, Anti-drug antibodies -
Identification and characterization of a flexile G-quadruplex in the distal promoter region of stemness gene REX1
Elsevier | 2023|R1WT to be a promising drug target. The endogenous existence of R1WT was confirmed by BG4 antibody derived chromatin immunoprecipitation ... -
The functions and mechanisms of post-translational modification in protein regulators of RNA methylation: Current status and future perspectives
Elsevier | 2023|. Despite advances in the structure and pharmacology of RNA methylation regulators that have improved drug discovery, regulating these proteins by ... -
Preparation methods, structural characteristics, and biological activity of polysaccharides from Platycodon grandiflorus
Elsevier | 2023|, anticancer, antiangiogenic, and immune regulatory properties. Incorporating the principles of traditional Chinese medicine, carrier concepts, and ...Keywords: Drug target -
Elucidation of the anti-colon cancer mechanism of Phellinus baumii polyphenol by an integrative approach of network pharmacology and experimental verification
Elsevier | 2023|constructed a network of “Disease-Drug-Pathways-Targets” and a protein-protein interaction (PPI) network among the targets using Cytoscape 3.9.1 ...
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