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1
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<i>Candida</i>: What Should Clinicians and Scientists Be Talking About?
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9
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An Introduction to the Medically Important <i>Candida</i> Species
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27
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Comparative Genomics of <i>Candida</i> Species
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45
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The Genetic Code of the <i>Candida</i> CTG Clade
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57
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Genome Instability and DNA Repair
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75
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Switching and Mating
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91
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Detection and Clinical Significance of Variability among <i>Candida</i> Isolates
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101
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Cell Cycle and Growth Control in <i>Candida</i> Species
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125
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Immunology of Invasive Candidiasis
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137
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Mucosal Immunity to <i>Candida albicans</i>
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155
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Innate Immunity to <i>Candida</i> Infections
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171
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Vaccines and Passive Immunity against Candidiasis
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185
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Salivary Histatins: Structure, Function, and Mechanisms of Antifungal Activity
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195
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The Cell Wall: Glycoproteins, Remodeling, and Regulation
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225
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Stress Responses in <i>Candida</i>
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243
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Adhesins in Opportunistic Fungal Pathogens
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261
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Encounters with Mammalian Cells: Survival Strategies of <i>Candida</i> Species
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283
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Gene Expression during the Distinct Stages of Candidiasis
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299
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Biofilm Formation in <i>Candida albicans</i>
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317
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<i>Candida</i> spp. in Microbial Populations and Communities: Molecular Interactions and Biological Importance
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331
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Back to the Future: <i>Candida</i> Mitochondria and Energetics
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343
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Antifungals: Drug Class, Mechanisms of Action, Pharmacokinetics/Pharmacodynamics, Drug‐Drug Interactions, Toxicity, and Clinical Use
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373
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The Impact of Antifungal Drug Resistance in the Clinic
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387
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Insights in Antifungal Drug Discovery
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403
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Multidrug Resistance Transcriptional Regulatory Networks in <i>Candida</i>
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417
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Mucosal Candidiasis
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429
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Systemic Candidiasis: Candidemia and Deep‐Organ Infections
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443
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New Developments in Diagnostics and Management of Invasive Candidiasis
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449
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The Epidemiology of Invasive Candidiasis
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481
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Cool Tools 1: Development and Application of a <i>Candida albicans</i> Two‐Hybrid System
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489
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Cool Tools 2: Development of a <i>Candida albicans</i> Cell Surface Protein Microarray
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497
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Cool Tools 3: Large‐Scale Genetic Interaction Screening in <i>Candida albicans</i>
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501
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Cool Tools 4: Imaging <i>Candida</i> Infections in the Live Host
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505
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Cool Tools 5: The <i>Candida albicans</i> ORFeome Project
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511
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Index
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i
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Front Matter