Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 1999
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Oxadiazole scaffolds in anti-tuberculosis drug discoveryDe, Suparna S. / Khambete, Mihir P. / Degani, Mariam S. et al. | 2019
- 2008
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Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitorsTasker, Nikhil R. / Rastelli, Ettore J. / Burnett, James C. et al. | 2019
- 2016
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Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current researchZhao, Liyu / Sun, Nannan / Tian, Linfeng et al. | 2019
- 2025
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Sleep modulating agentsChoi, Younggi / Raymer, Brian K. et al. | 2019
- 2034
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Small-molecule agents for the treatment of inflammatory bowel diseaseCurrie, Kevin S. / Patel, Leena / Sedillo, Kassandra F. et al. | 2019
- 2042
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Sulfonamide derivatives as multi-target agents for complex diseasesApaydın, Sinem / Török, Marianna et al. | 2019
- 2051
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MicroRNAs, intestinal inflammatory and tumorFeng, Yuan / Zhang, Yuan / Zhou, Di et al. | 2019
- 2059
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Broad-spectrum antifungal activity of spirooxindolo-pyrrolidine tethered indole/imidazole hybrid heterocycles against fungal pathogensBolous, Mina / Arumugam, Natarajan / Almansour, Abdulrahman I. et al. | 2019
- 2064
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Novel hydrophilic galactose-conjugated chlorin e6 derivatives for photodynamic therapy and fluorescence imagingMal'shakova, Marina V. / Pylina, Yana I. / Belykh, Dmitry V. et al. | 2019
- 2070
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Synthesis and biological evaluation of novel benzo[c][1,2,5]thiadiazol-5-yl and thieno[3,2-c]- pyridin-2-yl imidazole derivatives as ALK5 inhibitorsGuo, Zhen / Song, Xiaowei / Zhao, Li-Min et al. | 2019
- 2076
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In vitro characterization of MitE and MitB: Formation of N-acetylglucosaminyl-3-amino-5-hydroxybenzoyl-MmcB as a key intermediate in the biosynthesis of antitumor antibiotic mitomycinsOgasawara, Yasushi / Nakagawa, Yo / Maruyama, Chitose et al. | 2019
- 2079
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A new approach to procyanidins synthesis with potent anti-adipogenic effectsJeong, Gyeong Han / Cho, Jae-Hyeon / Kim, Tae Hoon et al. | 2019
- 2085
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Bioactive triterpene glycosides from the fruit of Stauntonia hexaphylla and insights into the molecular mechanism of its inflammatory effectsBa Vinh, Le / Jang, Hyun-Jae / Viet Phong, Nguyen et al. | 2019
- 2090
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Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927Labadie, Sharada S. / Li, Jun / Blake, Robert A. et al. | 2019
- 2094
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Synthesis of peptidomimetics and chemo-biological tools for CD95/PLCγ1 interaction analysisNguyen, Ha Thanh / Guégan, Jean-Philippe / Poissonnier, Amanda et al. | 2019
- 2100
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Optimization of oxadiazole derivatives with a spirocyclic cyclohexane structure as novel GPR119 agonistsHarada, Kazuhito / Mizukami, Jun / Watanabe, Takashi et al. | 2019
- 2107
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Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetoneIkenuma, Hiroshi / Koyama, Hiroko / Kajino, Naoya et al. | 2019
- 2112
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Rifamycin derivatives active against pathogenic rapidly-growing mycobacteriaCombrink, Keith D. / Ramos, Andrea Ramirez / Spring, Stephanie et al. | 2019
- 2116
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Bis(benzoyl) phosphate inactivators of beta-lactamase C from MtbWhite, Dawanna S. / Choy, Cindy J. / Moural, Timothy W. et al. | 2019
- 2119
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Synthesis and evaluation of tetrahydropyrazolopyridine inhibitors of anion exchange protein SLC26A4 (pendrin)Zhu, Jie S. / Lu, Julia Y. / Tan, Joseph-Anthony et al. | 2019
- 2124
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Structural development of 1H-pyrazolo-[3,4-b]pyridine-4-carboxylic acid derivatives as human peroxisome proliferator-activated receptor alpha (PPARα)-selective agonistsMiyachi, Hiroyuki / Yuzuriha, Tomohiro / Tabata, Ryotaro et al. | 2019
- 2129
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Novel conjugates of podophyllotoxin and coumarin: Synthesis, cytotoxicities, cell cycle arrest, binding CT DNA and inhibition of Topo IIβHao, Shu-Yi / Feng, Shi-Liang / Wang, Xing-Rong et al. | 2019
- 2136
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Discovery of novel 9H-purin derivatives as dual inhibitors of HDAC1 and CDK2Yu, Yu / Ran, Dongzhi / Jiang, Junhao et al. | 2019
- 2141
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In vitro selection of a 3′ terminal short protector that stabilizes transcripts to improve the translation efficiency in a wheat germ extractOgawa, Atsushi / Kutsuna, Akane / Takamatsu, Masashi et al. | 2019
- 2145
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Antioxidant capacities in various animal sera as measured with multiple free-radical scavenging methodSueishi, Yoshimi / Nii, Risako / Uda, Chikako et al. | 2019
- 2150
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Dual functional cholinesterase and PDE4D inhibitors for the treatment of Alzheimer’s disease: Design, synthesis and evaluation of tacrine-pyrazolo[3,4-b]pyridine hybridsPan, Tingting / Xie, Shishun / Zhou, Yan et al. | 2019
- 2153
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Design and synthesis of 4β-Acetamidobenzofuranone-podophyllotoxin hybrids and their anti-cancer evaluationPaidakula, Suresh / Nerella, Srinivas / Vadde, Ravinder et al. | 2019
- 2157
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Design, synthesis, and evaluation of a water soluble C5-monoketone type curcumin analogue as a potent amyloid β aggregation inhibitorHotsumi, Mayumi / Tajiri, Misato / Nikaido, Yuri et al. | 2019
- 2162
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Minimum structural requirements for inhibitors of the zinc finger protein TRAF6Radwan, Mohamed O. / Koga, Ryoko / Hida, Tomohiro et al. | 2019
- 2168
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Design, synthesis and biological evaluation of hypolipidemic compounds based on BRD4 inhibitor RVX-208Yu, Ping / Liu, Wenjing / Ren, Jinghui et al. | 2019
- 2173
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RNA fluorescence in situ hybridization hybridisation using photo-cross-linkable beacon probes containing pyranocarbazole in living E. coliFujimoto, Kenzo / Hashimoto, Misaki / Watanabe, Nanami et al. | 2019
- 2178
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Development of 99mTc-conjugated JS001 antibody for in vivo mapping of PD-1 distribution in murineGuo, Xiaoyi / Zhu, Hua / Liu, Teli et al. | 2019
- 2182
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Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptaseSasaki, Tomoaki / Gannam, Zira T.K. / Kudalkar, Shalley N. et al. | 2019
- 2189
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Homoharringtonine stabilizes secondary structure of guanine-rich sequence existing in the 5′-untranslated region of Nrf2Kang, Jong-Su / Lee, June / Nam, Le Ba et al. | 2019
- 2197
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Evaluation of quinoxaline compounds as ligands of a site adjacent to S2 (AS2) of cruzainFabian, Lucas / Martini, M. Florencia / Sarduy, Emir Salas et al. | 2019
- 2203
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Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarialsBerger, Olivier / Ortial, Stéphanie / Wein, Sharon et al. | 2019
- 2208
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Discovery and pharmacological evaluation of indole derivatives as potent and selective RORγt inverse agonist for multiple autoimmune conditionsShaikh, Nadim S. / Iyer, Jitesh P. / Munot, Yogesh S. et al. | 2019
- 2218
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Design, synthesis, bioactivity and mechanism of dithioacetal derivatives containing dioxyether moietyWang, Yanju / Zhang, Jian / He, Fangcheng et al. | 2019
- 2224
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SAR inspired by aldehyde oxidase (AO) metabolism: Discovery of novel, CNS penetrant tricyclic M4 PAMsChopko, Trevor C. / Han, Changho / Gregro, Alison R. et al. | 2019
- 2229
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Synthesis and biological evaluation of PSMA-targeting paclitaxel conjugatesMachulkin, Alexey E. / Skvortsov, Dmitry A. / Ivanenkov, Yan A. et al. | 2019
- 2236
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New dual ligands for the D2 and 5-HT1A receptors from the group of 1,8-naphthyl derivatives of LCAPZaręba, Przemysław / Jaśkowska, Jolanta / Śliwa, Paweł et al. | 2019
- 2243
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Synthesis of carbazoloquinone derivatives and their antileukemic activity via modulating cellular reactive oxygen speciesSuematsu, Natsumi / Ninomiya, Masayuki / Sugiyama, Hodaka et al. | 2019
- 2248
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Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agentsMantipally, Manohar / Gangireddy, Madhusudhana Reddy / Gundla, Rambabu et al. | 2019
- 2254
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l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophanHall, Colton / Wolfe, Hannah / Wells, Alyssa et al. | 2019
- 2259
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Development of a novel inducer for EBV lytic therapyTikhmyanova, Nadezhda / Paparoidamis, Nicholas / Romero-Masters, James et al. | 2019
- 2265
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Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonistsLu, Zhonghui / Duan, James J.-W. / Xiao, Haiyun et al. | 2019
- 2270
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Synthesis and biological evaluation of [18F]fluorovinpocetine, a potential PET radioligand for TSPO imagingNag, S. / Krasikova, R. / Airaksinen, A.J. et al. | 2019
- 2275
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Discovery of BR102375, a new class of non-TZD PPARγ full agonist for the treatment of type 2 diabetesChoung, Wonken / Yang, Deokmo / Kim, Hakdo et al. | 2019
- 2283
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Inhibition of neutral lipid synthesis by avarols from a marine spongeOhshiro, Taichi / Kobayashi, Keisuke / Suzuki, Aika et al. | 2019
- 2286
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Styryl quinazolinones and its ethynyl derivatives induce myeloid differentiationRadhakrishnan, Sridhar / Syed, Riyaz / Takei, Hisashi et al. | 2019
- 2290
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ER subtype selectivity of m-carborane-containing phenols: C-alkyl groups on the m-carborane cage enhance ERα selectivityOhta, Kiminori / Ogawa, Takumi / Kato, Koichi et al. | 2019
- 2294
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Design of a brain-penetrant CDK4/6 inhibitor for glioblastomaBronner, Sarah M. / Merrick, Karl A. / Murray, Jeremy et al. | 2019
- 2302
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Synthesis of novel benzothiazole amides: Evaluation of PPAR activity and anti-proliferative effects in paraganglioma, pancreatic and colorectal cancer cell linesAmmazzalorso, Alessandra / De Lellis, Laura / Florio, Rosalba et al. | 2019
- 2307
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SAR optimization studies on modified salicylamides as a potential treatment for acute myeloid leukemia through inhibition of the CREB pathwayChae, Hee-Don / Cox, Nick / Capolicchio, Samanta et al. | 2019
- 2316
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Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequenceFuret, Pascal / Salem, Bahaa / Mesrouze, Yannick et al. | 2019
- 2320
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The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of painShirahashi, Hiromitsu / Toriihara, Eisuke / Suenaga, Yoshihito et al. | 2019
- 2327
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Structure-activity relationships study of neolamellarin A and its analogues as hypoxia inducible factor-1 (HIF-1) inhibitorsLi, Guangzhe / Dong, Huijuan / Ma, Yao et al. | 2019
- 2332
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Discovery of 1,2,3-triazole-based fibroblast growth factor receptor modulatorsSakai, Hiroki / Inoue, Hidekazu / Toba, Tetsuya et al. | 2019
- 2338
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Discovery of novel N-methyl carbazole tethered rhodanine derivatives as direct inhibitors of Mycobacterium tuberculosis InhAShaikh, Mahamadhanif S. / Kanhed, Ashish M. / Chandrasekaran, Balakumar et al. | 2019
- 2345
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Discovery of 2,3′-diindolylmethanes as a novel class of PCSK9 modulatorsWinston-McPherson, Gabrielle N. / Xie, Haibo / Yang, Ka et al. | 2019
- 2349
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Exploring small molecules with pan-genotypic inhibitory activities against hepatitis C virus NS3/4A serine proteaseRen, Jinhong / Ojeda, Isabel / Patel, Maulik et al. | 2019
- 2354
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Fluorogenic 7-azidocoumarin and 3/4-azidophthalimide derivatives as indicators of reductase activity in microorganismsChalansonnet, Valerie / Lowe, John / Orenga, Sylvain et al. | 2019
- 2358
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Identification and characterization of potent and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B)Jin, Jia / Ye, Xiaoqing / Boateng, Derrick et al. | 2019
- 2364
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2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: Design, synthesis, and biological evaluationBazanov, Daniil R. / Pervushin, Nikolay V. / Savitskaya, Victoria Yu. et al. | 2019
- 2369
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Synthesis of N′-propylhydrazide analogs of hydroxamic inhibitors of histone deacetylases (HDACs) and evaluation of their impact on activities of HDACs and replication of hepatitis C virus (HCV)Kozlov, Maxim V. / Konduktorov, Konstantin A. / Shcherbakova, Anastasia S. et al. | 2019
- 2375
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Discovery of novel biaryl sulfonamide based Mcl-1 inhibitorsFollows, Bruce / Fessler, Shawn / Baumeister, Timm et al. | 2019
- 2383
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A graphene oxide fluorescent sensing platform for sensitive and specific detecting biomarker of radiation-resistant nasopharyngeal carcinomaYang, Zhaoqi / Qin, Lan / Yang, Dutao et al. | 2019
- 2387
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Synthesis and pharmacological evaluation of novel N-Mannich bases derived from 5,5-diphenyl and 5,5-di(propan-2-yl)imidazolidine-2,4-dione coreCzopek, Anna / Byrtus, Hanna / Zagórska, Agnieszka et al. | 2019
- 2393
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In vitro selection of aptamer S1 against MCF-7 human breast cancer cellsZhang, Wei-Yun / Chen, Hong-Li / Chen, Quan-Cheng et al. | 2019
- 2398
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PEGylated cyanine dye nanoparticles as photothermal agents for mosquito and cancer cell controlXu, Qi / Shen, Yujun / Zhang, Yongchao et al. | 2019
- 2405
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SAR studies in the sulfonyl carboxamide class of HBV capsid assembly modulatorsKuduk, Scott D. / Lam, Angela M. / Espiritu, Christine et al. | 2019
- 2410
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Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infectionsSpletstoser, Jared T. / Dreabit, Jason / Knox, Andrew N. et al. | 2019
- 2415
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Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi® and Epclusa®Link, John O. / Taylor, James G. / Trejo-Martin, Alejandra et al. | 2019
- 2428
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Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®Taylor, James G. / Zipfel, Sheila / Ramey, Kyla et al. | 2019
- 2437
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Corrigendum to “Aegeline, a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast” [Bioorg. Med. Chem. Lett. 29 (2019) 454–460]Derf, Asma / Sharma, Ankita / Bharate, Sandip B. et al. | 2019
- 2439
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Corrigendum to ‘Novel carbocyclic nucleoside analogs suppress glomerular mesangial cells proliferation and matrix protein accumulation through ROS-dependent mechanism in the diabetic milieu. II. Acylhydrazone-functionalized pyrimidines’ [Bioorg. Med. Chem. Lett. 26 (2016) 1020–1024]Bouhadir, Kamal H. / Koubeissi, Ali / Mohsen, Fatima A. et al. | 2019
- 2440
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Corrigendum to “Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury” [Bioorg. Med. Chem. Lett. 29(8) (2019) 995–1000]Goncalves, Maria B. / Clarke, Earl / Jarvis, Christopher I. et al. | 2019
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Graphical abstract TOC continued| 2019
- IBC
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Graphical abstract TOC| 2019
- ii
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Editorial Board| 2019