Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 3981
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Graphical contents list| 2009
- 3715
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Tetrahedron Young Investigator Award 2009: Carlos F. Barbas, III| 2009
- 3716
-
An efficient chemical approach to bispecific antibodies and antibodies of high valencyGavrilyuk, Julia I. et al. | 2009
- 3721
-
Potential scorpionate antibiotics: Targeted hydrolysis of lipid II containing model membranes by vancomycin–TACzyme conjugates and modulation of their antibacterial activity by Zn-ionsBauke Albada, H. et al. | 2009
- 3725
-
Development of enzymatically cleavable prodrugs derived from dendritic polyglycerolCalderón, Marcelo et al. | 2009
- 3729
-
Dynamic kinetic asymmetric transfer hydrogenation of racemic 2,4-diaryl-2,3-dihydrobenzo[b][1,4]diazepines catalyzed by chiral phosphoric acidsHan, Zhi-Yong et al. | 2009
- 3733
-
Tra1 as a screening target for transcriptional activation domain discoveryMajmudar, Chinmay Y. et al. | 2009
- 3736
-
Identification of a β3-peptide HIV fusion inhibitor with improved potency in live cellsBautista, Arjel D. et al. | 2009
- 3739
-
Kinetic resolution of aliphatic acyclic β-hydroxyketones by recombinant whole-cell Baeyer–Villiger monooxygenases—Formation of enantiocomplementary regioisomeric estersRehdorf, Jessica et al. | 2009
- 3744
-
Improving the species cross-reactivity of an antibody using computational designFarady, Christopher J. et al. | 2009
- 3748
-
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNAFurman, Jennifer L. et al. | 2009
- 3752
-
Using peptidyl aldehydes in activity-based proteomicsSabidó, Eduard et al. | 2009
- 3756
-
Identification of a disruptor of the MDM2-p53 protein–protein interaction facilitated by high-throughput in silico dockingLawrence, Harshani R. et al. | 2009
- 3760
-
Synthesis and SAR of C12–C13-oxazoline derivatives of epothilone APfeiffer, Bernhard et al. | 2009
- 3764
-
Brønsted acid-catalyzed Nazarov cyclization of pyrrole derivatives accelerated by microwave irradiationBachu, Prabhakar et al. | 2009
- 3767
-
Amino acid precursors for the detection of transketolase activity in Escherichia coli auxotrophsSimon, Grégory et al. | 2009
- 3771
-
Characterization of lassa virus cell entry inhibitors: Determination of the active enantiomer by asymmetric synthesisWhitby, Landon R. et al. | 2009
- 3775
-
Facile synthesis of cyclopeptide-centered multivalent glycoclusters with ‘click chemistry’ and molecular recognition study by surface plasmon resonanceChen, Yong-Xiang et al. | 2009
- 3779
-
CSI–FID: High throughput label-free detection of DNA binding moleculesHauschild, Karl E. et al. | 2009
- 3783
-
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurationsKasper, Amanda C. et al. | 2009
- 3787
-
Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidaseHarris, David A. et al. | 2009
- 3791
-
Predicting potential miRNA target sites within gene promotersYounger, Scott T. et al. | 2009
- 3795
-
Catalytic asymmetric synthesis of cyclic α-alkyl-amino acid derivatives having a tetrasubstituted α-carbonWang, Yong-Gang et al. | 2009
- 3798
-
Preparation of l-proline based aeruginosin 298-A analogs: Optimization of the P1-moietyWang, Guijun et al. | 2009
- 3804
-
Synthesis and reactivity of novel γ-phosphate modified ATP analoguesLee, Sarah E. et al. | 2009
- 3808
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An improved synthesis of α,β-unsaturated nitrones relevant to the stephacidins and analogs thereofHafensteiner, Benjamin D. et al. | 2009
- 3811
-
Synthesis and evaluation of a netropsin–proximicin-hybrid library for DNA binding and cytotoxicityWolter, Falko E. et al. | 2009
- 3816
-
Resin-supported catalytic dendrimers as multivalent artificial metallonucleasesZaupa, Giovanni et al. | 2009
- 3821
-
Multiple catalytic aldolase antibodies suitable for chemical programmingGoswami, Rajib Kumar et al. | 2009
- 3825
-
Structure–activity relationship studies of small-molecule inhibitors of Wnt responseLu, Jianming et al. | 2009
- 3828
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Identification of Hsp70 modulators through modeling of the substrate binding domainHaney, Conor M. et al. | 2009
- 3832
-
3-(Aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDBNguyen, Kong Thong et al. | 2009
- 3836
-
Synthesis of pochoxime prodrugs as potent HSP90 inhibitorsWang, Cuihua et al. | 2009
- 3841
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Cyclic glycopeptidomimetics through a versatile sugar-based scaffoldAltamura, Maria et al. | 2009
- 3845
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One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetasesMelançon, Charles E. et al. | 2009
- 3848
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Hypervalent iodine-catalyzed oxylactonization of ketocarboxylic acids to ketolactonesUyanik, Muhammet et al. | 2009
- 3852
-
Efficient syntheses of chiral myo-inositol derivatives—key intermediates in glycosylphosphatidylinositol (GPI) synthesesYu, Fei et al. | 2009
- 3856
-
Asymmetric synthesis of β,γ-unsaturated α-amino acids via efficient kinetic resolution with cinchona alkaloidsHang, Jianfeng et al. | 2009
- 3859
-
Origin of the stability conferred upon collagen by fluorinationShoulders, Matthew D. et al. | 2009
- 3863
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Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic productHayashi, Yujiro et al. | 2009
- 3866
-
Rapid identification of improved protein ligands using peptoid microarraysLim, Hyun-Suk et al. | 2009
- 3870
-
Side-chain assisted ligation in protein synthesisAjish Kumar, K.S. et al. | 2009
- 3875
-
Efficient synthesis of Idraparinux, the anticoagulant pentasaccharideChen, Chen et al. | 2009
- 3880
-
Biomolecular assembly by iterative oxime ligationsRenaudet, Olivier et al. | 2009
- 3884
-
Homogeneous gold-catalyzed efficient oxidative dimerization of propargylic acetatesCui, Li et al. | 2009
- 3888
-
Organocatalysis with endogenous compounds: Towards novel non-enzymatic reactionsAlberg, David G. et al. | 2009
- 3892
-
A flexizyme that selectively charges amino acids activated by a water-friendly leaving groupNiwa, Nobuyoshi et al. | 2009
- 3895
-
Enantioselective Henry (nitroaldol) reaction catalyzed by axially chiral guanidinesUbe, Hitoshi et al. | 2009
- 3899
-
Highly efficient synthesis of vinyl substituted triazoles by Au(I) catalyzed alkyne activationDuan, Haifeng et al. | 2009
- 3903
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Selective G-quadruplex ligands: The significant role of side chain charge density in a series of perylene derivativesMicheli, Emanuela et al. | 2009
- 3909
-
An enantioselective synthesis of (+)-(S)-[n]-gingerols via the l-proline-catalyzed aldol reactionMa, Shichao et al. | 2009
- 3912
-
Positioning of 99mTc-chelators influences radiolabeling, stability and biodistribution of Affibody moleculesEkblad, Torun et al. | 2009
- 3915
-
l-Prolinol as a highly enantioselective catalyst for Michael addition of cyclohexanone to nitroolefinsChua, Pei Juan et al. | 2009
- 3919
-
DNA sequence selectivity of hairpin polyamide turn unitsFarkas, Michelle E. et al. | 2009
- 3924
-
Selection of a buried salt bridge by phage displayVagt, Toni et al. | 2009
- 3928
-
Design and synthesis of novel hybrid benzamide–peptide histone deacetylase inhibitorsHu, Fang et al. | 2009
- 3932
-
A new synthesis of caged GABA compounds for studying GABAA receptorsFan, Lijun et al. | 2009
- 3934
-
Kinetic and mechanistic studies of proline-mediated direct intermolecular aldol reactionsZotova, Natalia et al. | 2009
- 3938
-
Organocatalytic synthesis and sterol 14α-demethylase binding interactions of enantioriched 3-(1H-1,2,4-triazol-1-yl)butyl benzoatesMing, Zhi-Hui et al. | 2009
- 3941
-
Inhibition of Pseudomonas aeruginosa quorum sensing by AI-2 analogsGanin, Hadas et al. | 2009
- 3945
-
Expedient solid-phase synthesis of both symmetric and asymmetric diol libraries targeting aspartic proteasesShi, Haibin et al. | 2009
- 3949
-
Catalyst-free tandem aldol condensation-Michael addition of 1,3-cyclohexanediones with enolizable aldehydesRohr, Kerstin et al. | 2009
- 3952
-
Organocatalytic enantioselective hetero-Diels–Alder reaction of aldehydes and o-benzoquinone diimide: Synthesis of optically active hydroquinoxalinesLi, Jun-Long et al. | 2009
- 3955
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Organocatalytic α-hydroxymethylation of cyclopentanone with aqueous formaldehyde: Easy access to chiral δ-lactonesMase, Nobuyuki et al. | 2009
- 3959
-
Enzymatic activation of hydrophobic self-immolative dendrimers: The effect of reporters with ionizable functional groupsAvital-Shmilovici, Michal et al. | 2009
- 3963
-
Dendrimers ended by non-symmetrical azadiphosphonate groups: Synthesis and immunological propertiesMarchand, Patrice et al. | 2009
- 3967
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Chiral N-phosphonyl imine chemistry: Asymmetric synthesis of α,β-diamino esters by reacting phosphonyl imines with glycine enolatesAi, Teng et al. | 2009
- 3970
-
Restricted spacer tolerance of a zinc finger nuclease with a six amino acid linkerShimizu, Yuka et al. | 2009
- 3973
-
Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomidesYamamoto, Takeshi et al. | 2009
- 3977
-
Synthesis and SAR study of novel pseudo-steroids as potent and selective progesterone receptor antagonistsJain, Nareshkumar et al. | 2009
- 4011
-
Dopamine D3 receptor antagonists: The quest for a potentially selective PET ligand. Part two: Lead optimizationMicheli, Fabrizio / Holmes, Ian / Arista, Luca et al. | 2009
- 4014
-
Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part IFuret, Pascal / Schoepfer, Joseph / Radimerski, Thomas et al. | 2009
- 4018
-
Metal ion CHElate-aSSisted LIGAtion (CHESS LIGA) for SNP detection on microarraysHien, Le Thi / Oretskaya, Tatiana S. / Zatsepin, Timofei S. et al. | 2009
- 4022
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The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonistsLunniss, Gillian E. / Barnes, Ashley A. / Barton, Nick et al. | 2009
- 4026
-
Structure–Activity Relationship of novel phenylacetic CXCR1 inhibitorsSablone, Manolo Rocco / Cesta, Maria Candida / Moriconi, Alessio et al. | 2009
- 4031
-
Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitorsDenhart, Derek J. / Deskus, Jeffrey A. / Ditta, Jonathan L. et al. | 2009
- 4034
-
Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitorsShi, Yan / Zhang, Jing / Shi, Mengxiao et al. | 2009
- 4042
-
Identification of aminoethyl pyrrolo dihydroisoquinolinones as novel poly(ADP-ribose) polymerase-1 inhibitorsBranca, Danila / Cerretani, Mauro / Jones, Philip et al. | 2009
- 4046
-
Assessment of new 2′-O-acetalester protecting groups for regular RNA synthesis and original 2′-modified proRNAMartin, Anthony R. / Lavergne, Thomas / Vasseur, Jean-Jacques et al. | 2009
- 4046
-
Assessment of new 2prime-O-acetalester protecting groups for regular RNA synthesis and original 2prime-modified proRNAMartin, A. R. / Lavergne, T. / Vasseur, J. J. et al. | 2009
- 4050
-
Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)Miyashiro, Julie / Woods, Keith W. / Park, Chang H. et al. | 2009
- 4055
-
Synthesis and evaluation of 5-benzylidene(thio)barbiturate-β-d-glycosides as mushroom tyrosinase inhibitorsYan, Qin / Cao, Rihui / Yi, Wei et al. | 2009
- 4055
-
Synthesis and evaluation of 5-benzylidene(thio)barbiturate-b-d-glycosides as mushroom tyrosinase inhibitorsYan, Q. / Cao, R. / Yi, W. et al. | 2009
- 4059
-
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)Kuduk, Scott D. / Chang, Ronald K. / Wai, Jenny M.-C. et al. | 2009
- 4064
-
Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivativesFrançois, Isabelle E.J.A. / Cammue, Bruno P.A. / Bresseleers, Sara et al. | 2009
- 4067
-
Bis-anthracenyl isoxazolyl amides have enhanced anticancer activityGajewski, Mariusz P. / Beall, Howard / Schnieder, Mark et al. | 2009
- 4070
-
Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitorsKoltun, Dmitry O. / Zilbershtein, Timur M. / Migulin, Vasily A. et al. | 2009
- 4075
-
Development of a selective and potent radioactive ligand for histamine H3 receptors: A compound potentially useful for receptor occupancy studiesMitobe, Yuko / Ito, Sayaka / Mizutani, Takashi et al. | 2009
- 4079
-
Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activityXu, Peng / Liu, Lu / Chen, Xiao-zhuo et al. | 2009
- 4084
-
Peperomins as anti-inflammatory agents that inhibit the NF-κB signaling pathwayTsutsui, Chieko / Yamada, Yuriko / Ando, Masayoshi et al. | 2009
- 4084
-
Peperomins as anti-inflammatory agents that inhibit the NF-kB signaling pathwayTsutsui, C. / Yamada, Y. / Ando, M. et al. | 2009
- 4088
-
Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitorsOwen, Dafydd R. / Walker, John K. / Jon Jacobsen, E. et al. | 2009
- 4092
-
Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring systemHughes, Robert O. / Walker, John K. / Cubbage, Jerry W. et al. | 2009
- 4097
-
Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitorsEdmondson, Scott D. / Mastracchio, Anthony / Cox, Jason M. et al. | 2009
- 4102
-
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian α-carbonic anhydrase isoformsParkkila, Seppo / Innocenti, Alessio / Kallio, Heini et al. | 2009
- 4102
-
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian a-carbonic anhydrase isoformsParkkila, S. / Innocenti, A. / Kallio, H. et al. | 2009
- 4107
-
7-Cycloalkylcamptothecin derivatives: Preparation and biological evaluationLi, Mingzong / Jin, Wei / Jiang, Chen et al. | 2009
- 4110
-
Tetrahydrocarbazole amides with potent activity against human papillomavirusesGudmundsson, Kristjan S. / Boggs, Sharon D. / Sebahar, Paul R. et al. | 2009
- 4115
-
Synthesis and evaluation of new endomorphin analogues modified at the Pro2 residueTorino, Domenica / Mollica, Adriano / Pinnen, Francesco et al. | 2009
- 4119
-
Synthesis of novel quinoxaline derivatives and its cytotoxic activitiesTanimori, Shinji / Nishimura, Takeshi / Kirihata, Mitsunori et al. | 2009
- 4122
-
Synthesis and evaluation of 3Prime- and 4Prime-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000Raju, R. / Castillo, B. F. / Richardson, S. K. et al. | 2009
- 4122
-
Synthesis and evaluation of 3″- and 4″-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000Raju, Ravinder / Castillo, Bernard F. / Richardson, Stewart K. et al. | 2009
- 4126
-
First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor XaVerghese, Jenson / Liang, Aiye / Sidhu, Preet Pal Singh et al. | 2009
- 4130
-
The synthesis and biological evaluation of a novel series of C7 non-basic substituted fluoroquinolones as antibacterial agentsHuang, Xiaoguang / Chen, Dongliang / Wu, Ning et al. | 2009
- 4134
-
Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitorsKang, Iou-Jiun / Wang, Li-Wen / Hsu, Sheng-Ju et al. | 2009
- 4139
-
Bisintercalator-containing dinuclear iron(III) complex: An efficient artificial nucleaseChen, Xiaoqiang / Fan, Jiangli / Peng, Xiaojun et al. | 2009
- 4143
-
Synthesis and antitumor activity of substituted triazolo[4,3-a]pyrimidin-6-sulfonamide with an incorporated thiazolidinone moietyHafez, Hend N. / El-Gazzar, Abdel-Rahman B.A. et al. | 2009
- 4148
-
Synthesis of calcium phosphate-binding liposome for drug deliveryAnada, Takahisa / Takeda, Yoichi / Honda, Yoshitomo et al. | 2009
- 4151
-
Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamideUto, Yoshikazu / Ogata, Tsuneaki / Harada, Jun et al. | 2009
- 4159
-
Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluationUto, Yoshikazu / Ogata, Tsuneaki / Kiyotsuka, Yohei et al. | 2009
- 4167
-
Synthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotorLiu, Zong-ying / He, Xiao-bo / Yang, Zhao-yong et al. | 2009
- 4171
-
Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting groupAihara, Yoshiyuki / Yoshida, Atsusi / Furuta, Takumi et al. | 2009
- 4175
-
Real-time fluorescence monitoring of GSK3b-catalyzed phosphoryation by use of a BODIPY-based Zn(II)-Dpa chemosensorSakamoto, T. / Inoue, M. a. / Ojida, A. et al. | 2009
- 4175
-
Real-time fluorescence monitoring of GSK3β-catalyzed phosphoryation by use of a BODIPY-based Zn(II)–Dpa chemosensorSakamoto, Takashi / Inoue, Masa-aki / Ojida, Akio et al. | 2009
- 4178
-
N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cellsYamazaki, Yoshimitsu / Kawano, Yasuhiro / Yamanaka, Akiko et al. | 2009
- 4183
-
Discovery and functional evaluation of diverse novel human CB1 receptor ligandsFoloppe, Nicolas / Benwell, Karen / Brooks, Teresa D. et al. | 2009
- 4191
-
Discovery of N-[(1-aryl-1H-indazol-5-yl)methyl]amides derivatives as smoothened antagonists for inhibition of the hedgehog pathwayDessole, Gabriella / Branca, Danila / Ferrigno, Federica et al. | 2009
- 4196
-
Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitorsOrvieto, Federica / Branca, Danila / Giomini, Claudia et al. | 2009
- 4201
-
Discovery of β-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IVNordhoff, Sonja / Cerezo-Gálvez, Silvia / Deppe, Holger et al. | 2009
- 4201
-
Discovery of b-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IVNordhoff, S. / Cerezo-Galvez, S. / Deppe, H. et al. | 2009
- 4204
-
Design, synthesis and biological evaluation of 2H-benzo[b][1,4] oxazine derivatives as hypoxia targeted compounds for cancer therapeuticsDas, Bhaskar C. / Madhukumar, Ankanahlli V. / Anguiano, Jaime et al. | 2009
- 4207
-
5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109bSkinner, Philip J. / Webb, Peter J. / Sage, Carleton R et al. | 2009
- 4210
-
Synthesis of 9-β-d-arabinofuranosylguanine by combined use of two whole cell biocatalystsMédici, Rosario / Iribarren, Adolfo M. / Lewkowicz, Elizabeth S. et al. | 2009
- 4210
-
Synthesis of 9-b-d-arabinofuranosylguanine by combined use of two whole cell biocatalystsMedici, R. / Iribarren, A. M. / Lewkowicz, E. S. et al. | 2009
- 4213
-
Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activityAlagha, Ahmed / Moman, Edelmiro / Adamo, Mauro F.A. et al. | 2009
- 4217
-
First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligandPalmioli, Alessandro / Sacco, Elena / Abraham, Sherwin et al. | 2009
- 4223
-
A stabilized demethoxyviridin derivative inhibits PI3 kinaseYuan, Hushan / Pupo, Monica T. / Blois, Joe et al. | 2009
- 4228
-
Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitorsHosoda, Shinnosuke / Matsuda, Daisuke / Tomoda, Hiroshi et al. | 2009
- 4232
-
Synthesis, structure–activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H3 receptor inverse agonistsSasaki, Takahide / Takahashi, Toshiyuki / Nagase, Tsuyoshi et al. | 2009
- 4237
-
Synthesis and antimultidrug resistance evaluation of icariin and its derivativesLiu, Dong-Fang / Li, Yan-Ping / Ou, Tian-Miao et al. | 2009
- 4241
-
Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureasHart, Terance / Macias, Alba T. / Benwell, Karen et al. | 2009
- 4245
-
N-(4-Fluorobenzyl)-3-hydroxy-9,9-dimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrazino[1,2-a]pyrimidine-2-carboxamides a novel class of potent HIV-1 integrase inhibitorsPetrocchi, Alessia / Jones, Philip / Rowley, Michael et al. | 2009
- 4250
-
The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4′-azidocytidine (R1479)McGuigan, Christopher / Kelleher, Mary Rose / Perrone, Plinio et al. | 2009
- 4250
-
The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4prime-azidocytidine (R1479)McGuigan, C. / Kelleher, M. R. / Perrone, P. et al. | 2009
- 4255
-
Induction of apoptosis in HuH-7 cancer cells by monoterpene and b-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegansMansoor, T. A. / Ramalho, R. M. / Mulhovo, S. et al. | 2009
- 4255
-
Induction of apoptosis in HuH-7 cancer cells by monoterpene and β-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegansMansoor, Tayyab A. / Ramalho, Rita M. / Mulhovo, Silva et al. | 2009
- 4259
-
Unsymmetrical non-adamantyl N,Nprime-diaryl urea and amide inhibitors of soluble expoxide hydrolaseAnandan, S. K. / Webb, H. K. / Do, Z. N. et al. | 2009
- 4259
-
Unsymmetrical non-adamantyl N,N′-diaryl urea and amide inhibitors of soluble expoxide hydrolaseAnandan, Sampath-Kumar / Webb, Heather K. / Do, Zung N. et al. | 2009
- 4264
-
Discovery and optimization of a novel Neuromedin B receptor antagonistFu, Jiasheng / Shuttleworth, Stephen J. / Connors, Richard V. et al. | 2009
- 4268
-
Optimization of 2-piperidin-4-yl-acetamides as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Designing out hERG inhibitionBerglund, Susanne / Egner, Bryan J. / Gradén, Henrik et al. | 2009
- 4274
-
Optimization of piperidin-4-yl-urea-containing melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Reducing hERG-associated liabilitiesBerglund, Susanne / Egner, Bryan J. / Gradén, Henrik et al. | 2009
- 4280
-
Dipeptidyl nitrile inhibitors of Cathepsin LAsaad, Nabil / Bethel, Paul A. / Coulson, Michelle D. et al. | 2009
- 4284
-
Structure–activity relationship of etomidate derivatives at the GABAA receptor: Comparison with binding to 11β-hydroxylaseAtucha, Erika / Hammerschmidt, Friedrich / Zolle, Ilse et al. | 2009
- 4284
-
Structure-activity relationship of etomidate derivatives at the GABAA receptor: Comparison with binding to 11b-hydroxylaseAtucha, E. / Hammerschmidt, F. / Zolle, I. et al. | 2009
- 4288
-
Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramideVeerapen, Natacha / Brigl, Manfred / Garg, Salil et al. | 2009
- 4288
-
Synthesis and biological activity of a-galactosyl ceramide KRN7000 and galactosyl (a12) galactosyl ceramideVeerapen, N. / Brigl, M. / Garg, S. et al. | 2009
- 4292
-
Discovery of novel aminothiadiazole amides as selective EP3 receptor antagonistsHilfiker, Mark A. / Wang, Ning / Hou, Xiaoping et al. | 2009
- 4296
-
Photochemical control of FlAsH labeling of proteinsWilkins, Bryan J. / Yang, Xu / Cropp, T. Ashton et al. | 2009
- 4299
-
Synthesis and structure–activity relationships of γ-carboline derivatives as potent and selective cysLT1 antagonistsBonjoch, Josep / Diaba, Faïza / Pagès, Lluís et al. | 2009
- 4299
-
Synthesis and structure-activity relationships of g-carboline derivatives as potent and selective cysLT1 antagonistsBonjoch, J. / Diaba, F. / Pages, L. et al. | 2009
- 4303
-
Pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione derivatives as novel small molecule chaperone amplifiersZhou, Yuefen / Wei, Linyi / Brady, Thomas P. et al. | 2009
- 4308
-
Potent agonists of the Hedgehog signaling pathwayBrunton, Shirley A. / Stibbard, John H.A. / Rubin, Lee L. et al. | 2009
- 4312
-
Structure–activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of actionBolognesi, Maria Laura / Bartolini, Manuela / Rosini, Michela et al. | 2009
- 4316
-
The phosphoramidate ProTide approach greatly enhances the activity of β-2′-C-methylguanosine against hepatitis C virusMcGuigan, Christopher / Perrone, Plinio / Madela, Karolina et al. | 2009
- 4316
-
The phosphoramidate ProTide approach greatly enhances the activity of b-2prime-C-methylguanosine against hepatitis C virusMcGuigan, C. / Perrone, P. / Madela, K. et al. | 2009
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Identification of compounds exhibiting inhibitory activity toward the Pseudomonas tolaasii toxin tolaasin I using in silico docking calculations, NMR binding assays, and in vitro hemolytic activity assaysLee, Younggiu / Woo, Yoonkyung / Lee, Soohyun et al. | 2009
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Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activityKameda, Minoru / Kobayashi, Kensuke / Ito, Hirokatsu et al. | 2009
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Structure-based de novo design and biochemical evaluation of novel Cdc25 phosphatase inhibitorsPark, Hwangseo / Bahn, Young Jae / Ryu, Seong Eon et al. | 2009
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Fe(II) phthalocyanine catalyzed oxidation of dGMP by molecular oxygenKuznetsova, Aleksandra A. / Solovyeva, Lyudmila I. / Kaliya, Oleg L. et al. | 2009
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Identification of a chromone-based retinoid containing a polyolefinic side chain via facile synthetic routesSun, Weilin / Carroll, Patrick J. / Soprano, Dianne R. et al. | 2009
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[11C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient 11C-O-methylation and initial small animal PET studiesRiss, Patrick J. / Hooker, Jacob M. / Alexoff, David et al. | 2009
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Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kB inhibitor, DMAPT (LC-1)Neelakantan, S. / Nasim, S. / Guzman, M. L. et al. | 2009
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Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-κB inhibitor, DMAPT (LC-1)Neelakantan, Sundar / Nasim, Shama / Guzman, Monica L. et al. | 2009
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Substituted benzothiadizine inhibitors of Hepatitis C virus polymeraseShaw, Antony N. / Tedesco, Rosanna / Bambal, Ramesh et al. | 2009
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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitorsTedesco, Rosanna / Chai, Deping / Darcy, Michael G. et al. | 2009
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Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the α6∗ subtypeBreining, Scott R. / Bencherif, Merouane / Grady, Sharon R. et al. | 2009
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Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the a6* subtypeBreining, S. R. / Bencherif, M. / Grady, S. R. et al. | 2009
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Effect of varying chain length between P1 and P1′ position of tripeptidomimics on activity of angiotensin-converting enzyme inhibitorsChaudhary, Snehlata / Vats, Ishwar Dutt / Chopra, Madhu et al. | 2009
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Effect of varying chain length between P1 and P1prime position of tripeptidomimics on activity of angiotensin-converting enzyme inhibitorsChaudhary, S. / Vats, I. D. / Chopra, M. et al. | 2009
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Antitumor activity of deoxypodophyllotoxin isolated from Anthriscus sylvestris: Induction of G2/M cell cycle arrest and caspase-dependent apoptosisYong, Yeonjoong / Shin, Soon Young / Lee, Young Han et al. | 2009
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Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitorsPark, Hwangseo / Li, Minghua / Choi, Jungeun et al. | 2009
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Ionic interactions for substituted MCH1R inhibitors studied by pKa valuesLee, Joo Yun / Lee, Hyuk / Lim, Jung Yun et al. | 2009
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Brain-penetrating 2-aminobenzimidazole H1-antihistamines for the treatment of insomniaCoon, Timothy / Moree, Wilna J. / Li, Binfeng et al. | 2009