Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 1801
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Graphical contents list| 2010
- 1816
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Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruziHolloway, G.A. / Parisot, J.P. / Novello, P.M. et al. | 2010
- 1819
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Antimicrobial activity of long-chain (E)-3-alken-2-onesWood, William F. / Kubo, Aya / Shaffer, Tony B. et al. | 2010
- 1821
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Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding siteMcLean, Larry R. / Zhang, Ying / Li, Hua et al. | 2010
- 1825
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Benzimidazole Thumb Pocket I finger-loop inhibitors of HCV NS5B polymerase: Improved drug-like properties through C-2 SAR in three sub-seriesBeaulieu, Pierre L. / Dansereau, Nathalie / Duan, Jianmin et al. | 2010
- 1830
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Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonistsLemoine, Rémy C. / Petersen, Ann C. / Setti, Lina et al. | 2010
- 1834
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Efficient approach for profiling photoaffinity labeled peptides with a cleavable biotinyl photoprobeBongo, Nlandu B. / Tomohiro, Takenori / Hatanaka, Yasumaru et al. | 2010
- 1837
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Unprecedented NES non-antagonistic inhibitor for nuclear export of Rev from Sida cordifoliaTamura, Satoru / Kaneko, Masafumi / Shiomi, Atsushi et al. | 2010
- 1840
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Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitorKakuta, Hiroki / Fukai, Ryosuke / Xiaoxia, Zheng et al. | 2010
- 1844
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Synthesis and antitumor activity of 1-mesityl-3-(2-naphthoylmethano)-1H-imidazolium bromideZeng, Xianghui / Yang, Xiaodong / Zhang, Yanli et al. | 2010
- 1848
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Ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit—Potential anti-metastatic drugsJanser, Romy F.J. / Meka, Ranjith K. / Bryant, Zack E. et al. | 2010
- 1848
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Ethacrynic acid analogues lacking the a,b-unsaturated carbonyl unit-Potential anti-metastatic drugsJanser, R. F. / Meka, R. K. / Bryant, Z. E. et al. | 2010
- 1851
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Identification of a urea bioisostere of a triazole oxytocin antagonistBrown, Alan / Ellis, Dave / Wallace, Olga et al. | 2010
- 1854
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Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) alkylation subunitBoyle, Kristopher E. / MacMillan, Karen S. / Ellis, David A. et al. | 2010
- 1858
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Design of two new chemotypes for inhibiting the Janus kinase 2 by scaffold morphingFuret, Pascal / Gerspacher, Marc / Pissot-Soldermann, Carole et al. | 2010
- 1861
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Ultrasmall particle of iron oxide—RGD peptidomimetic conjugate: synthesis and characterisationRerat, Vincent / Laurent, Sophie / Burtéa, Carmen et al. | 2010
- 1866
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Synthesis and evaluation of a library of 2,5-bisdiamino-benzoquinone derivatives as probes to modulate protein–protein interactions in prionsTran, Hoang Ngoc Ai / Bongarzone, Salvatore / Carloni, Paolo et al. | 2010
- 1869
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Novel powerful water-soluble lipid immunoadjuvants inducing mouse dendritic cell maturation and B cell proliferation using TLR2 pathwaySpanedda, Maria Vittoria / Heurtault, Béatrice / Weidner, Steffen et al. | 2010
- 1873
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SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regeliiRyu, Young Bae / Park, Su-Jin / Kim, Young Min et al. | 2010
- 1877
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Discovery and SAR of hydantoin TACE inhibitorsYu, Wensheng / Guo, Zhuyan / Orth, Peter et al. | 2010
- 1881
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Synthesis, antibacterial and antifungal activities of some carbazole derivativesZhang, Fei-Fei / Gan, Lin-Ling / Zhou, Cheng-He et al. | 2010
- 1885
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SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine pKa in enzyme inhibitionRajapakse, Hemaka A. / Nantermet, Philippe G. / Selnick, Harold G. et al. | 2010
- 1890
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Synthesis and structure–activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonistsHartz, Richard A. / Ahuja, Vijay T. / Schmitz, William D. et al. | 2010
- 1895
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Heterocyclic acetamide and benzamide derivatives as potent and selective β3-adrenergic receptor agonists with improved rodent pharmacokinetic profilesGoble, Stephen D. / Wang, Liping / Howell, K. Lulu et al. | 2010
- 1895
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Heterocyclic acetamide and benzamide derivatives as potent and selective b3-adrenergic receptor agonists with improved rodent pharmacokinetic profilesGoble, S. D. / Wang, L. / Howell, K. L. et al. | 2010
- 1900
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Rigidified 2-aminopyrimidines as histamine H4 receptor antagonists: Effects of substitution about the rigidifying ringKoenig, John R. / Liu, Huaqing / Drizin, Irene et al. | 2010
- 1905
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Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R)Vrudhula, Vivekananda M. / Dasgupta, Bireshwar / Pin, Sokhom S. et al. | 2010
- 1910
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Synthesis of amino acid conjugates to 2-imino-3-methylene-5-carboxypyrrolidine and 2-imino-3-methylene-6-carboxypiperidineMitchell, Robin E. et al. | 2010
- 1913
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Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonistsHe, Shuwen / Dobbelaar, Peter H. / Liu, Jian et al. | 2010
- 1918
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3D-QSAR and docking studies on transforming growth factor (TGF)-β receptor 1 antagonistsGeldenhuys, Werner J. / Nakamura, Hiroshi et al. | 2010
- 1918
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3D-QSAR and docking studies on transforming growth factor (TGF)-b receptor 1 antagonistsGeldenhuys, W. J. / Nakamura, H. et al. | 2010
- 1924
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Structure-based design and synthesis of novel P2/P3 modified, non-peptidic b-secretase (BACE-1) inhibitorsHanessian, S. / Shao, Z. / Betschart, C. et al. | 2010
- 1924
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Structure-based design and synthesis of novel P2/P3 modified, non-peptidic β-secretase (BACE-1) inhibitorsHanessian, Stephen / Shao, Zhihui / Betschart, Claudia et al. | 2010
- 1928
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New adjuvants to enhance anticoagulant activity of WarfarinStromich, Jeremiah J. / Weber, Ashley K. / Mirzaei, Yousef R. et al. | 2010
- 1933
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Synthesis, characterization, and in vitro antimicrobial activities of 5-alkenyl/hydroxyalkenyl-2-phenylamine-1,3,4-oxadiazoles and thiadiazolesFarshori, Nida N. / Banday, Mudasir R. / Ahmad, Anis et al. | 2010
- 1939
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The development of benzimidazoles as selective rho kinase inhibitorsSessions, E. Hampton / Smolinski, Michael / Wang, Bo et al. | 2010
- 1944
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Bioactivity-guided isolation of cytotoxic triterpenoids from the trunk of Berberis koreanaKim, Ki Hyun / Choi, Sang Un / Lee, Kang Ro et al. | 2010
- 1948
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Syntheses of water-soluble [60]fullerene derivatives and their enhancing effect on neurite outgrowth in NGF-treated PC12 cellsTsumoto, Hiroki / Kawahara, Syo / Fujisawa, Yuki et al. | 2010
- 1953
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Novel glitazones: Design, synthesis, glucose uptake and structure–activity relationshipsKumar, B.R. Prashantha / Nanjan, M.J. et al. | 2010
- 1957
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Synthesis of fluorinated C-mannopeptides as sialyl Lewisx mimics for E- and P-selectin inhibitionGouge-Ibert, Vanessa / Pierry, Camille / Poulain, Florent et al. | 2010
- 1961
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Synthesis, chiral resolution, and determination of novel furan lignan derivatives with potent anti-tumor activitySun, Hai Ling / Wang, Tian Tian / Lv, Zhi Liang et al. | 2010
- 1965
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Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCθ inhibitorsBoschelli, Diane H. / Subrath, Joan / Niu, Chuansheng et al. | 2010
- 1969
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Simple and conveniently accessible bi-fluorescence-labeled substrates for amylasesOka, Hiroyuki / Koyama, Tetsuo / Hatano, Ken et al. | 2010
- 1972
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Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M1 PAMBridges, Thomas M. / Kennedy, J. Phillip / Noetzel, Meredith J. et al. | 2010
- 1976
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Synthesis and evaluation of 2-pyridylbenzothiazole, 2-pyridylbenzoxazole and 2-pyridylbenzofuran derivatives as 11C-PET imaging agents for β-amyloid plaquesSwahn, Britt-Marie / Wensbo, David / Sandell, Johan et al. | 2010
- 1976
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Synthesis and evaluation of 2-pyridylbenzothiazole, 2-pyridylbenzoxazole and 2-pyridylbenzofuran derivatives as 11C-PET imaging agents for b-amyloid plaquesSwahn, B. M. / Wensbo, D. / Sandell, J. et al. | 2010
- 1981
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Discovery of novel inhibitors for DHODH via virtual screening and X-ray crystallographic structuresMcLean, Larry R. / Zhang, Ying / Degnen, William et al. | 2010
- 1985
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Rational design of potent GSK3b inhibitors with selectivity for Cdk1 and Cdk2Lesuisse, D. / Dutruc-Rosset, G. / Tiraboschi, G. et al. | 2010
- 1985
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Rational design of potent GSK3β inhibitors with selectivity for Cdk1 and Cdk2Lesuisse, Dominique / Dutruc-Rosset, Gilles / Tiraboschi, Gilles et al. | 2010
- 1990
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The synthesis and Angiotensin Converting Enzyme (ACE) inhibitory activity of chalcones and their pyrazole derivativesBonesi, Marco / Loizzo, Monica R. / Statti, Giancarlo A. et al. | 2010
- 1994
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The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymeraseTanis, Steven P. / Strohbach, Joseph W. / Parker, Timothy T. et al. | 2010
- 2001
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Design and evaluation of Trypanosoma brucei metacaspase inhibitorsBerg, Maya / Veken, Pieter Van der / Joossens, Jurgen et al. | 2010
- 2007
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Substituted fused bicyclic pyrrolizinones as potent, orally bioavailable hNK1 antagonistsMorriello, Gregori J. / Mills, Sander G. / Johnson, Tricia et al. | 2010
- 2013
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The identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposureHolmes, Ian P. / Blunt, Richard J. / Lorthioir, Olivier E. et al. | 2010
- 2017
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Discovery of a new series of 5-HT1A receptor agonistsFranchini, Silvia / Prandi, Adolfo / Sorbi, Claudia et al. | 2010
- 2021
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Bisleuconothine A, an eburnane–aspidosperma bisindole alkaloid from Leuconotis griffithiiHirasawa, Yusuke / Shoji, Tomokazu / Arai, Takashi et al. | 2010
- 2025
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Design and synthesis of novel deoxybenzoin derivatives as FabH inhibitors and anti-inflammatory agentsLi, Huan-Qiu / Luo, Yin / Lv, Peng-Cheng et al. | 2010
- 2029
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Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirineSkepper, Colin K. / Dalisay, Doralyn S. / Molinski, Tadeusz F. et al. | 2010
- 2033
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Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cellsChoi, Soo Jeong / Moon, Myoung Ju / Lee, So Deok et al. | 2010
- 2038
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Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Seprime-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)-against colon cancerDesai, D. / Madhunapantula, S. V. / Gowdahalli, K. et al. | 2010
- 2038
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Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se′-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)—against colon cancerDesai, Dhimant / Madhunapantula, SubbaRao V. / Gowdahalli, Krishnegowda et al. | 2009
- 2044
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SelSA, selenium analogs of SAHA as potent histone deacetylase inhibitorsDesai, Dhimant / Salli, Ugur / Vrana, Kent E. et al. | 2009
- IFC
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Editorial board| 2010