Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 2083
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Graphical contents list| 2009
- 2099
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Synthesis and SAR of 4-substituted-2-aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitorsHumphries, Paul S. / Lafontaine, Jennifer A. / Agree, Charles S. et al. | 2009
- 2103
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Synthesis and evaluation of novel neamine derivatives effectively targeting to RNAXu, Yanli / Jin, Hongwei / Yang, Zhenjun et al. | 2009
- 2107
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1-(5-Carboxyindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2a: Synthesis and properties of bioisosteric benzimidazole, benzotriazole and indazole analoguesBovens, S. / Kaptur, M. / Elfringhoff, A. S. et al. | 2009
- 2107
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1-(5-Carboxyindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2α: Synthesis and properties of bioisosteric benzimidazole, benzotriazole and indazole analoguesBovens, Stefanie / Kaptur, Martina / Elfringhoff, Alwine Schulze et al. | 2009
- 2112
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Synthesis and activity in enhancing long-term potentiation (LTP) of clausenamide stereoisomersFeng, Zhiqiang / Li, Xingzhou / Zheng, Guojun et al. | 2009
- 2116
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Relationships between the structures of flavanone derivatives and their effects in enhancing Early growth response-1 gene expressionLee, Sunhee / Woo, Yoonkyung / Shin, Soon Young et al. | 2009
- 2121
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GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole–tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109aImbriglio, Jason E. / Chang, Sookhee / Liang, Rui et al. | 2009
- 2125
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Discovery of potent and selective DP1 receptor antagonists in the azaindole seriesLeblanc, Yves / Roy, Patrick / Dufresne, Claude et al. | 2009
- 2129
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Discovery and structure–activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitisAkama, Tsutomu / Baker, Stephen J. / Zhang, Yong-Kang et al. | 2009
- 2133
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Modulations of the amide function of the preferential dopamine D3 agonist (R,R)-S32504: Improvements of affinity and selectivity for D3 versus D2 receptorsPeglion, Jean-Louis / Poitevin, Christophe / La Cour, Clotilde Mannoury et al. | 2009
- 2139
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Discovery of novel dihydro-9,10-ethano-anthracene carboxamides as glucocorticoid receptor modulatorsYang, Bingwei V. / Vaccaro, Wayne / Doweyko, Arthur M. et al. | 2009
- 2144
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Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)aminohexyl group for 5′-terminal modificationKojima, Naoshi / Takebayashi, Toshie / Mikami, Akiko et al. | 2009
- 2144
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Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)aminohexyl group for 5prime-terminal modificationKojima, N. / Takebayashi, T. / Mikami, A. et al. | 2009
- 2148
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Anti-HBV agents. Part 2: Synthesis and in vitro anti-hepatitis B virus activities of alisol A derivativesZhang, Quan / Jiang, Zhi-Yong / Luo, Jie et al. | 2009
- 2154
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Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitorLiu, Jie / Shiono, Jun / Shimizu, Kuniyoshi et al. | 2009
- 2158
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5,6-Diarylanthranilo-1,3-dinitriles as a new class of antihyperglycemic agentsSingh, Fateh V. / Parihar, Amrita / Chaurasia, Sumit et al. | 2009
- 2162
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Synthesis and antiviral activities of novel acylhydrazone derivatives targeting HIV-1 capsid proteinTian, Baohe / He, Meizi / Tang, Shixing et al. | 2009
- 2168
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Synthesis and cytotoxicity of 2-cyano-28-hydroxy-lup-1-en-3-onesKoohang, Ali / Majewski, Nathan D. / Szotek, Erika L. et al. | 2009
- 2172
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Fluorinated non-imidazole histamine H3 receptor antagonistsIsensee, K. / Amon, M. / Galaparti, A. et al. | 2009
- 2176
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Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum productionMitchell, Lorna H. / Hu, Lain-Yen / Nguyen, Maria et al. | 2009
- 2179
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Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitorZhang, Penglie / Huang, Wenrong / Wang, Lingyan et al. | 2009
- 2186
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Anthranilamide-based N,N-dialkylbenzamidines as potent and orally bioavailable factor Xa inhibitors: P4 SARZhang, Penglie / Bao, Liang / Fan, Jingmei et al. | 2009
- 2190
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In vitro and in vivo SAR of pyrido[3,4-d]pyramid-4-ylamine based mGluR1 antagonistsMantell, Simon J. / Gibson, Karl R. / Osborne, Simon A. et al. | 2009
- 2195
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Facile synthesis of de-O-sulfated salacinols: Revision of the structure of neosalacinol, a potent a-glucosidase inhibitorTanabe, G. / Xie, W. / Ogawa, A. et al. | 2009
- 2195
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Facile synthesis of de-O-sulfated salacinols: Revision of the structure of neosalacinol, a potent α-glucosidase inhibitorTanabe, Genzoh / Xie, Weijia / Ogawa, Ai et al. | 2009
- 2199
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Structure–activity relationships of diverse annonaceous acetogenins against human tumor cellsYang, Haijun / Zhang, Ning / Li, Xiang et al. | 2009
- 2203
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Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosisCastagnolo, Daniele / Radi, Marco / Dessì, Filippo et al. | 2009
- 2206
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A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic propertiesMoss, Neil / Choi, Younggi / Cogan, Derek et al. | 2009
- 2211
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Regioisomerism-dependent TLR7 agonism and antagonism in an imidazoquinolineShukla, Nikunj M. / Kimbrell, Matthew R. / Malladi, Subbalakshmi S. et al. | 2009
- 2215
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Exploring the PI3Kα and γ binding sites with 2,6-disubstituted isonicotinic derivativesCherian, Philip T. / Koikov, Leonid N. / Wortman, Matthew D. et al. | 2009
- 2215
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Exploring the PI3Ka and g binding sites with 2,6-disubstituted isonicotinic derivativesCherian, P. T. / Koikov, L. N. / Wortman, M. D. et al. | 2009
- 2220
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Piperidinyl-2-phenethylamino inhibitors of DPP-IV for the treatment of Type 2 diabetesBenbow, John W. / Andrews, Kim A. / Aubrecht, Jiri et al. | 2009
- 2224
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[35S]GTPγS binding studies of amphiphilic drugs-activated Gi proteins: A caveatManetti, Dina / Mannelli, Lorenzo Di Cesare / Dei, Silvia et al. | 2009
- 2224
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[35S]GTPgS binding studies of amphiphilic drugs-activated Gi proteins: A caveatManetti, D. / Mannelli, L. D. / Dei, S. et al. | 2009
- 2230
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1-Aryl-3,4-dihydroisoquinoline inhibitors of JNK3Christopher, John A. / Atkinson, Francis L. / Bax, Benjamin D. et al. | 2009
- 2235
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Optimisation of a series of potent, selective and orally bioavailable GlyT1 inhibitorsThomson, Joanne L. / Blackaby, Wesley P. / Jennings, Andrew S.R. et al. | 2009
- 2240
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Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivityLavieri, Robert / Scott, Sarah A. / Lewis, Jana A. et al. | 2009
- 2244
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Discovery of 5-pyrrolopyridinyl-2-thiophenecarboxamides as potent AKT kinase inhibitorsSeefeld, Mark A. / Rouse, Meagan B. / McNulty, Kenneth C. et al. | 2009
- 2249
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2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturationWeterings, Jimmy J. / Khan, Selina / van der Heden van Noort, Gerbrand J. et al. | 2009
- 2252
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Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategyWijtmans, Maikel / Verzijl, Dennis / van Dam, Cindy M.E. et al. | 2009
- 2258
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Synthesis and β-amyloid binding properties of rhenium 2-phenylbenzothiazolesLin, Kuo-Shyan / Debnath, Manik L. / Mathis, Chester A. et al. | 2009
- 2258
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Synthesis and b-amyloid binding properties of rhenium 2-phenylbenzothiazolesLin, K. S. / Debnath, M. L. / Mathis, C. A. et al. | 2009
- 2263
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Tricyclic HIV integrase inhibitors V. SAR studies on the benzyl moietyJin, Haolun / Metobo, Sammy / Jabri, Salman et al. | 2009
- 2266
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The preparation of 2,6-disubstituted pyridinyl phosphine oxides as novel anti-cancer agentsLam, Kim Hung / Gambari, Roberto / Yuen, Marcus Chun Wah et al. | 2009
- 2270
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Synthesis and anti-inflammatory activity of the major metabolites of imrecoxibFeng, Zhiqiang / Chu, Fengming / Guo, Zongru et al. | 2009
- 2273
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Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moietiesSinger, Mathilde / Lopez, Marie / Bornaghi, Laurent F. et al. | 2009
- 2277
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Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitorsGellibert, F. / Fouchet, M.-H. / Nguyen, V.-L. et al. | 2009
- 2282
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Novel small molecule activators of β-catenin-mediated signaling pathway: structure–activity relationships of indirubinsPark, Eun-Jung / Choi, Soo Jeong / Kim, Yong-Chul et al. | 2009
- 2282
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Novel small molecule activators of b-catenin-mediated signaling pathway: structure-activity relationships of indirubinsPark, E. J. / Choi, S. J. / Kim, Y. C. et al. | 2009
- 2285
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Turn-on fluorescent probe with visible light excitation for labeling of hexahistidine tagged proteinKamoto, Mie / Umezawa, Naoki / Kato, Nobuki et al. | 2009
- 2289
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Syntheses of novel high affinity ligands for opioid receptorsWentland, Mark P. / Lou, Rongliang / Lu, Qun et al. | 2009
- 2295
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Inhibitors of hepatitis C virus NS3/4A: α-Ketoamide based macrocyclic inhibitorsAvolio, Salvatore / Robertson, Keith / Hernando, Josè Ignacio Martin et al. | 2009
- 2295
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Inhibitors of hepatitis C virus NS3/4A: a-Ketoamide based macrocyclic inhibitorsAvolio, S. / Robertson, K. / Hernando, J. I. et al. | 2009
- 2299
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Inhibitors of potassium channels KV1.3 and IK-1 as immunosuppressantsPegoraro, Stefano / Lang, Martin / Dreker, Tobias et al. | 2009
- 2305
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Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure–activity relationships of the 2-aryl groupSirisoma, Nilantha / Pervin, Azra / Nguyen, Bao et al. | 2009
- 2310
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Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement productsGauthier, Charles / Legault, Jean / Piochon, Marianne et al. | 2009
- 2315
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Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonistsEvindar, Ghotas / Satz, Alexander L. / Bernier, Sylvie G. et al. | 2009
- 2320
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Synthesis of protein tyrosine phosphatase 1B inhibitors: Model validation and docking studiesSaxena, Anil K. / Pandey, Gyanendra / Gupta, Swati et al. | 2009
- 2324
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QSAR analysis of pyrazolidine-3,5-diones derivatives as Dyrk1A inhibitorsKoo, Kyung Ah / Kim, Nam Doo / Chon, Yong Sog et al. | 2009
- 2329
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Design and optimization of selective serotonin re-uptake inhibitors with high synthetic accessibility Part 1Andrews, Mark / Brown, Alan / Chiva, Jean-Yves et al. | 2009
- 2333
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Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitorsLin, Ronghui / Johnson, Sigmond G. / Connolly, Peter J. et al. | 2009
- 2338
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8-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: Dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors—Part IIBromidge, Steven M. / Bertani, Barbara / Borriello, Manuela et al. | 2009
- 2343
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Synthesis of boronic acid derivatives of tyropeptin: Proteasome inhibitorsWatanabe, Takumi / Momose, Isao / Abe, Masatoshi et al. | 2009
- 2346
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N-Hydroxy-(4-oxime)-cinnamide: A versatile scaffold for the synthesis of novel histone deacetilase (HDAC) inhibitorsGiannini, Giuseppe / Marzi, Mauro / Pezzi, Riccardo et al. | 2009
- 2350
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Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activatorsBemis, Jean E. / Vu, Chi B. / Xie, Roger et al. | 2008
- 2354
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Discovery of potent non-urea inhibitors of soluble epoxide hydrolaseXie, Yuli / Liu, Yidong / Gong, Gangli et al. | 2008
- 2360
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Synthesis and in vitro activity of new tetrahydronaphtho[1,2-b]azepine derivatives against Trypanosoma cruzi and Leishmania chagasi parasitesPalma, Alirio / Yépes, Andrés Felipe / Leal, Sandra Milena et al. | 2008
- 2364
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Corrigendum to “Novel 3,5-diaryl pyrazolines as human acyl-CoA:cholesterol acyltransferase inhibitors” [Bioorg. Med. Chem. Lett. 14 (2004) 3109–3112]Jeong, Tae-Sook / Kim, Kyung Soon / An, Sojin et al. | 2004
- 2365
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Corrigendum to “Novel tetrahydro-β-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)” [Bioorg. Med. Chem. Lett. 17 (2007) 4657–4663]Trujillo, John I. / Meyers, Marvin J. / Anderson, David R. et al. | 2007
- 2365
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Corrigendum to "Novel tetrahydro-b-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)" [Bioorg. Med. Chem. Lett. 17 (2007) 4657-4663]Trujillo, J. I. / Meyers, M. J. / Anderson, D. R. et al. | 2009
- 2366
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Corrigendum to "Structure-based design and synthesis of macrocyclic peptidomimetic b-secretase (BACE-1) inhibitors" [Bioorg. Med. Chem. Lett. 19 (2009) 1361-1365]Machauer, R. / Veenstra, S. / Rondeau, J. M. et al. | 2009
- 2366
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Corrigendum to “Structure-based design and synthesis of macrocyclic peptidomimetic β-secretase (BACE-1) inhibitors” [Bioorg. Med. Chem. Lett. 19 (2009) 1361–1365]Machauer, Rainer / Veenstra, Siem / Rondeau, Jean-Michel et al. | 2009
- 2367
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Corrigendum to “Synthesis and antibacterial activities of novel oxazolidinones having cyclic sulfonamide moieties” [Bioorg. Med. Chem. Lett. 18 (2008) 5815–5818]Kim, Seong Jong / Jung, Myung-Ho / Yoo, Kyung Ho et al. | 2008
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Instructions to contributors| 2009
- IFC
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Editorial board| 2009