Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 6527
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Graphical contents list| 2012
- 6540
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How hydrogen bonds impact P-glycoprotein transport and permeabilityDesai, Prashant V. / Raub, Thomas J. / Blanco, Maria-Jesus et al. | 2012
- 6549
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Design, synthesis and biological activities of sorafenib derivatives as antitumor agentsYao, Jianwen / He, Zuopeng / Chen, Jing et al. | 2012
- 6554
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Identification of a novel and orally available benzimidazole derivative as an NPY Y5 receptor antagonist with in vivo efficacyTamura, Yuusuke / Omori, Naoki / Kouyama, Naoki et al. | 2012
- 6559
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Chemotherapy of leishmaniasis. Part XI: Synthesis and bioevaluation of novel isoxazole containing heteroretinoid and its amide derivativesSuryawanshi, S.N. / Tiwari, Avinash / Chandra, Naveen et al. | 2012
- 6563
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Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor of the metalloenzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR)Zinglé, Catherine / Kuntz, Lionel / Tritsch, Denis et al. | 2012
- 6568
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A hierarchical method for molecular docking using cloud computingKang, Ling / Guo, Quan / Wang, Xicheng et al. | 2012
- 6573
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Design, synthesis, and structure–activity-relationship of phenyl imidazoles as potent Smoothened antagonistsCheng, Dai / Han, Dong / Gao, Wenqi et al. | 2012
- 6577
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Downregulation of mdr1 and abcg2 genes is a mechanism of inhibition of efflux pumps mediated by polymeric amphiphilesCuestas, María L. / Castillo, Amalia I. / Sosnik, Alejandro et al. | 2012
- 6580
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Formylated polyamines as peptidomimeticsJavor, Sacha / Janowsky, Aaron / Johnson, Robert et al. | 2012
- 6583
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Design, synthesis, and evaluation of potential prodrugs of DFMO for reductive activationYang, Yanhui / Voak, Andrew / Wilkinson, Shane R. et al. | 2012
- 6587
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3,3′-Disubstituted bipolar biphenyls as inhibitors of nuclear receptor coactivator bindingWeiser, Patrick T. / Williams, Anna B. / Chang, Ching-Yi et al. | 2012
- 6587
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3,3prime-Disubstituted bipolar biphenyls as inhibitors of nuclear receptor coactivator bindingWeiser, P. T. / Williams, A. B. / Chang, C. Y. et al. | 2012
- 6591
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Design, synthesis and in vitro activities on anti-platelet aggregation of 4-methoxybenzene-1,3-isophthalamidesLiu, Xiu Jie / Shi, Xin Xin / Zhong, Yong Liang et al. | 2012
- 6596
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Identification of novel 3,5-diarylpyrazoline derivatives containing salicylamide moiety as potential anti-melanoma agentsLi, Qing-Shan / Lv, Xian-Hai / Zhang, Yan-Bin et al. | 2012
- 6602
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Design, synthesis, spectral and biological evaluation of novel 1-allyl substituted 2,6-diphenylpiperidin-4-ones and its derivatives of oximes/oxime ethersNarayanan, Kuppusamy / Shanmugam, Mani / Jothivel, Sarangan et al. | 2012
- 6608
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First total synthesis of prasinic acid and its anticancer activityChakor, Narayan / Patil, Ganesh / Writer, Diana et al. | 2012
- 6611
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Synthesis, anti-inflammatory and antimicrobial evaluation of novel 1-acetyl-3,5-diaryl-4,5-dihydro (1H) pyrazole derivatives bearing urea, thiourea and sulfonamide moietiesKeche, Ashish P. / Hatnapure, Girish D. / Tale, Rajesh H. et al. | 2012
- 6616
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Novel 3-substituted-1-aryl-5-phenyl-6-anilinopyrazolo[3,4-d]pyrimidin-4-ones: Docking, synthesis and pharmacological evaluation as a potential anti-inflammatory agentsYewale, Sandeep B. / Ganorkar, Saurabh B. / Baheti, Kamalkishor G. et al. | 2012
- 6621
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Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’ binding poseVaidya, Aditya Sudheer / Neelarapu, Raghupathi / Madriaga, Antonett et al. | 2012
- 6628
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Structure-based design of pyridopyrimidinediones as dipeptidyl peptidase IV inhibitorsLam, Betty / Zhang, Zhiyuan / Stafford, Jeffery A. et al. | 2012
- 6632
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Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase BVan der Walt, Mietha M. / Terre’Blanche, Gisella / Petzer, Anél et al. | 2012
- 6636
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Identification of pyrimidine derivatives as hSMG-1 inhibitorsGopalsamy, Ariamala / Bennett, Eric M. / Shi, Mengxiao et al. | 2012
- 6642
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Anti-HIV-1 activity of resveratrol derivatives and synergistic inhibition of HIV-1 by the combination of resveratrol and decitabineClouser, Christine L. / Chauhan, Jay / Bess, Matthew A. et al. | 2012
- 6647
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Substituted pyrazolones require N2 hydrogen bond donating ability to protect against cytotoxicity from protein aggregation of mutant superoxide dismutase 1Trippier, Paul C. / Benmohamed, Radhia / Kirsch, Donald R. et al. | 2012
- 6651
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[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: Introduction of N 3-phenylpyrazinones as potential CRF-R1 PET imaging agentsDeskus, Jeffrey A. / Dischino, Douglas D. / Mattson, Ronald J. et al. | 2012
- 6656
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Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptorMaloney, Patrick R. / Khan, Pasha / Hedrick, Michael et al. | 2012
- 6661
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Hydrolytic instability of the important orexin 1 receptor antagonist SB-334867: Possible confounding effects on in vivo and in vitro studiesMcElhinny, Charles J. Jr. / Lewin, Anita H. / Mascarella, S. Wayne et al. | 2012
- 6665
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Discovery of 4-morpholino-pyrimidin-6-one and 4-morpholino-pyrimidin-2-one-containing Phosphoinositide 3-kinase (PI3K) p110β isoform inhibitors through structure-based fragment optimisationGiordanetto, Fabrizio / Wållberg, Andreas / Cassel, Johan et al. | 2012
- 6665
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Discovery of 4-morpholino-pyrimidin-6-one and 4-morpholino-pyrimidin-2-one-containing Phosphoinositide 3-kinase (PI3K) p110b isoform inhibitors through structure-based fragment optimisationGiordanetto, F. / Wallberg, A. / Cassel, J. et al. | 2012
- 6671
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Discovery of phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H-pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistanceGiordanetto, Fabrizio / Wållberg, Andreas / Ghosal, Saswati et al. | 2012
- 6671
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Discovery of phosphoinositide 3-kinases (PI3K) p110b isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H-pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistanceGiordanetto, F. / Wallberg, A. / Ghosal, S. et al. | 2012
- 6677
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Synthesis and in vitro and in vivo anticancer activity of novel 3-methyl-5H-isoxazolo[5′,4′:5,6]pyrido[2,3-b]indolesRajanarendar, E. / Govardhan Reddy, K. / Ramakrishna, S. et al. | 2012
- 6677
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Synthesis and in vitro and in vivo anticancer activity of novel 3-methyl-5H-isoxazolo[5prime,4prime:5,6]pyrido[2,3-b]indolesRajanarendar, E. / Govardhan Reddy, K. / Ramakrishna, S. et al. | 2012
- 6681
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Diarylheptanoid glycosides from Tacca plantaginea and their effects on NF-κB activation and PPAR transcriptional activityQuang, Tran Hong / Ngan, Nguyen Thi Thanh / Minh, Chau Van et al. | 2012
- 6681
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Diarylheptanoid glycosides from Tacca plantaginea and their effects on NF-kB activation and PPAR transcriptional activityQuang, T. H. / Ngan, N. T. / Minh, C. V. et al. | 2012
- 6688
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The discovery of CCR3/H1 dual antagonists with reduced hERG riskBahl, Ash / Barton, Patrick / Bowers, Keith et al. | 2012
- 6694
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Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092Bahl, Ash / Barton, Patrick / Bowers, Keith et al. | 2012
- 6700
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Synthesis and in vitro antitumour screening of 2-(β-d-xylofuranosyl)thiazole-4-carboxamide and two novel tiazofurin analogues with substituted tetrahydrofurodioxol moiety as a sugar mimicPopsavin, Mirjana / Spaić, Saša / Svirčev, Miloš et al. | 2012
- 6700
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Synthesis and in vitro antitumour screening of 2-(b-d-xylofuranosyl)thiazole-4-carboxamide and two novel tiazofurin analogues with substituted tetrahydrofurodioxol moiety as a sugar mimicPopsavin, M. / Spaic, S. / Svircev, M. et al. | 2012
- 6705
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Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activitySurivet, Jean-Philippe / Lange, Roland / Hubschwerlen, Christian et al. | 2012
- 6712
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Identification of a glutathione peroxidase inhibitor that reverses resistance to anticancer drugs in human B-cell lymphoma cell linesSchulz, Riad / Emmrich, Thomas / Lemmerhirt, Heidi et al. | 2012
- 6716
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Synthesis and evaluation of naphthoic acid derivatives as fluorescent probes to screen advanced glycation end-products breakersSéro, Luc / Calard, François / Sanguinet, Lionel et al. | 2012
- 6721
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Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templatesSund, Christian / Belda, Oscar / Borkakoti, Neera et al. | 2012
- 6728
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Chemotherapy of leishmaniasis. Part IX: Synthesis and bioevaluation of aryl substituted ketene dithioacetals as antileishmanial agentsKumar, Santosh / Tiwari, Avinash / Suryawanshi, S.N. et al. | 2012
- 6731
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Novel cyanocombretastatins as potent tubulin polymerisation inhibitorsJalily, Pouria H. / Hadfield, John A. / Hirst, Nicholas et al. | 2012
- 6735
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Acremomannolipin A, the potential calcium signal modulator with a characteristic glycolipid structure from the filamentous fungus Acremonium strictumSugiura, Reiko / Kita, Ayako / Tsutsui, Nozomi et al. | 2012
- 6740
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Effect of substituents at phenyl group of 7,7prime-dioxo-9,9prime-epoxylignane on antifungal activityNishiwaki, H. / Ouchi, M. / Matsugi, J. et al. | 2012
- 6740
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Effect of substituents at phenyl group of 7,7′-dioxo-9,9′-epoxylignane on antifungal activityNishiwaki, Hisashi / Ouchi, Maya / Matsugi, Junko et al. | 2012
- 6745
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Synthesis and pharmacological evaluation of N-substituted 2-(2-oxo-2H-chromen-4-yloxy)propanamide as cyclooxygenase inhibitorsRambabu, D. / Mulakayala, Naveen / Ismail et al. | 2012
- 6750
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Part II. Development of novel colchicine-derived immunosuppressants with improved pharmacokinetic propertiesChang, Dong-Jo / Lee, Sujin / Jang, Jaebong et al. | 2012
- 6756
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Optimisation of pharmacokinetic properties in a neutral series of 11b-HSD1 inhibitorsScott, J. S. / Gill, A. L. / Godfrey, L. et al. | 2012
- 6756
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Optimisation of pharmacokinetic properties in a neutral series of 11β-HSD1 inhibitorsScott, James S. / Gill, Adrian L. / Godfrey, Linda et al. | 2012
- 6762
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Evaluation of structure-derived pharmacophore of soluble epoxide hydrolase inhibitors by virtual screeningMoser, Daniel / Achenbach, Janosch / Klingler, Franca-Maria et al. | 2012
- 6766
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4-Substituted-2-phenylquinazolines as inhibitors of BCRPJuvale, Kapil / Wiese, Michael et al. | 2012
- 6770
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Cyclic tetrapeptides with thioacetate tails or intramolecular disulfide bridge as potent inhibitors of histone deacetylasesHoque, Md. Ashraful / Arai, Toru / Nishino, Norikazu et al. | 2012
- 6773
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Corrigendum to “A highly sensitive fluorescent viscosity sensor” [Bioorg. Med. Chem. Lett. 22 (2012) 5780–5783]Yusop, Rahimi M. / Unciti-Broceta, Asier / Bradley, Mark et al. | 2012
- 6774
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Corrigendum to “Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR” [Bioorg. Med. Chem. Lett. 22 (2012) 5098–5103]Le, Phuong T. / Cheng, Hengmiao / Ninkovic, Sacha et al. | 2012
- 6774
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Corrigendum to "Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Ka and mTOR" [Bioorg. Med. Chem. Lett. 22 (2012) 5098-5103]Le, P. T. / Cheng, H. / Ninkovic, S. et al. | 2012
- 6775
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Corrigendum to “Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives” [Bioorg. Med. Chem. Lett. 22 (2012) 5791–5794]Serra, Silvia / Chicca, Andrea / Delogu, Giovanna et al. | 2012
- IFC
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Editorial board| 2012