Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 3391
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Graphical contents list| 2015
- 3409
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Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approachMcConnell, Jeanette R. / Buckton, Laura K. / McAlpine, Shelli R. et al. | 2015
- 3415
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The structural use of carbostyril in physiologically active substancesTashima, Toshihiko et al. | 2015
- 3420
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Cyclin dependent kinase (CDK) inhibitors as anticancer drugsSánchez-Martínez, Concepción / Gelbert, Lawrence M. / Lallena, María José et al. | 2015
- 3436
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Discovery and optimization of a highly efficacious class of 5-aryl-2-aminopyridines as FMS-like tyrosine kinase 3 (FLT3) inhibitorsLiu, Gang / Abraham, Sunny / Liu, Xing et al. | 2015
- 3442
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Discovery of new acetylcholinesterase inhibitors with small core structures through shape-based virtual screeningChen, Yao / Liu, Zong-liang / Fu, Ting-ming et al. | 2015
- 3447
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Activity of aminoferrocene-based prodrugs against prostate cancerSchikora, Margot / Reznikov, Alexander / Chaykovskaya, Liudmila et al. | 2015
- 3451
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C4 phenyl aporphines with selective h5-HT2B receptor affinityKapadia, Nirav / Harding, Wayne W. et al. | 2015
- 3455
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Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activityJo, Yang Hee / Kim, Seon Beom / Liu, Qing et al. | 2015
- 3458
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Hybrid pyrimidine alkynyls inhibit the clinically resistance related Bcr-AblT315I mutantLu, Xiaoyun / Zhang, Zhang / Ren, Xiaomei et al. | 2015
- 3464
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Novel inhibitor against Malassezia globosa LIP1 (SMG1), a potential anti-dandruff targetGuo, Shaohua / Huang, Wenkang / Zhang, Jian et al. | 2015
- 3468
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Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical spaceRoss, Audrey G. / Benton, Bret M. / Chin, Donovan et al. | 2015
- 3476
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Targeted fluorescent probes for detection of oxidative stress in the mitochondriaYapici, Nazmiye B. / Mandalapu, Srinivas / Michael Gibson, K. et al. | 2015
- 3481
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Human SIRT3 tripeptidic inhibitors containing Nε-thioacetyl-lysineChen, Bing / Wang, Juan / Huang, Yajun et al. | 2015
- 3488
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Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeysFischer, Christian / Zultanski, Susan L. / Zhou, Hua et al. | 2015
- 3495
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Potent benzoazepinone γ-secretase modulators with improved bioavailabilityMethot, Joey L. / Fischer, Christian / Li, Chaomin et al. | 2015
- 3501
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Discovery of 11β-hydroxysteroid dehydrogenase type 1 inhibitorHong, Sung Pyo / Nam, Ky Youb / Shin, Young June et al. | 2015
- 3507
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The selectivity of 6-nor-ABA and 7′-nor-ABA for abscisic acid receptor subtypesTakeuchi, Jun / Ohnishi, Toshiyuki / Okamoto, Masanori et al. | 2015
- 3511
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Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid estersAntoszczak, Michał / Sobusiak, Maria / Maj, Ewa et al. | 2015
- 3515
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Further optimization of the mGlu5 PAM clinical candidate VU0409551/JNJ-46778212: Progress and challenges towards a back-up compoundZhou, Ya / Malosh, Chrysa / Conde-Ceide, Susana et al. | 2015
- 3520
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Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonistsLai, Zhong / He, Shuwen / Sherer, Edward C. et al. | 2015
- 3526
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Quinolizidine alkaloids reduced mortality in EV71-infected mice by compensating for the levels of T cellsYang, Yajun / Guan, Feifei / Bai, Lin et al. | 2015
- 3529
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Geraniin inhibits TGF-β1-induced epithelial–mesenchymal transition and suppresses A549 lung cancer migration, invasion and anoikis resistanceKo, Hyeonseok et al. | 2015
- 3535
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Novel hybrids of 3-n-butylphthalide and edaravone: Design, synthesis and evaluations as potential anti-ischemic stroke agentsSheng, Xiao / Hua, Kai / Yang, Chunyu et al. | 2015
- 3541
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Hedgehog inhibitors from Withania somniferaYoneyama, Tatsuro / Arai, Midori A. / Sadhu, Samir K. et al. | 2015
- 3545
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Metronidazole hydrazone conjugates: Design, synthesis, antiamoebic and molecular docking studiesAnsari, Mohammad Fawad / Siddiqui, Shadab Miyan / Agarwal, Subhash M. et al. | 2015
- 3550
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Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktisVullo, Daniela / De Luca, Viviana / Del Prete, Sonia et al. | 2015
- 3556
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Monoterpene indole alkaloid hydrazone derivatives with apoptosis inducing activity in human HCT116 colon and HepG2 liver carcinoma cellsPaterna, Angela / Borralho, Pedro M. / Gomes, Sofia E. et al. | 2015
- 3560
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Synthesis of the aggregation pheromone of the Colorado potato beetle from its degradation productWacławczyk-Biedroń, Weronika / Frąckowiak-Wojtasek, Bożena / Strub, Daniel et al. | 2015
- 3564
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The 2′,4′-dihydroxychalcone could be explored to develop new inhibitors against the glycerol-3-phosphate dehydrogenase from Leishmania speciesPassalacqua, Thais G. / Torres, Fábio A.E. / Nogueira, Camila T. et al. | 2015
- 3569
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Identification and optimisation of a 4′,5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitorsFairhurst, Robin A. / Imbach-Weese, Patricia / Gerspacher, Marc et al. | 2015
- 3575
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Identification and optimisation of 4,5-dihydrobenzo[1,2-d:3,4-d]bisthiazole and 4,5-dihydrothiazolo[4,5-h]quinazoline series of selective phosphatidylinositol-3 kinase alpha inhibitorsFairhurst, Robin A. / Gerspacher, Marc / Imbach-Weese, Patricia et al. | 2015
- 3582
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Discovery of a novel tricyclic 4H-thiazolo[5′,4′:4,5]pyrano[2,3-c]pyridine-2-amino scaffold and its application in a PI3Kα inhibitor with high PI3K isoform selectivity and potent cellular activityGerspacher, Marc / Fairhurst, Robin A. / Mah, Robert et al. | 2015
- 3585
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The discovery of oxazolones-grafted spirooxindoles via three-component diversity oriented synthesis and their preliminary biological evaluationDong, Hui / Song, Sicheng / Li, Jingjing et al. | 2015
- 3592
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Anticancer effect and mechanism of a Se-modified porphyrin Au(III) complexYang, Feng-Rui / Li, Yue / Zhang, Xiao-Hong et al. | 2015
- 3597
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Synthesis and cytotoxic properties of tryptamine derivativesSalikov, Rinat F. / Belyy, Aleksandr Yu. / Khusnutdinova, Nailya S. et al. | 2015
- 3601
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Synthesis and anticancer activity of novel curcumin–quinolone hybridsRaghavan, Saiharish / Manogaran, Prasath / Gadepalli Narasimha, Krishna Kumari et al. | 2015
- 3606
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Lipid-lowering polyketides from a soft coral-derived fungus Cladosporium sp. TZP29Zhu, Meilin / Gao, Huquan / Wu, Chongming et al. | 2015
- 3610
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Synthesis of novel cationic spermine-conjugated phosphotriester oligonucleotide for improvement of cell membrane permeabilityHayashi, Junsuke / Hamada, Tomoko / Sasaki, Ikumi et al. | 2015
- 3616
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Antiproliferative and tumor inhibitory studies of 2,3 disubstituted 4-thiazolidinone derivativesSharath Kumar, Kothanahally S. / Hanumappa, Ananda / Vetrivel, Maruthai et al. | 2015
- 3621
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Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding modeGessier, François / Kallen, Joerg / Jacoby, Edgar et al. | 2015
- 3626
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Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinaseBagdanoff, Jeffrey T. / Jain, Rama / Han, Wooseok et al. | 2015
- 3630
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Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5)Singh, Sheo B. / Kaelin, David E. / Meinke, Peter T. et al. | 2015
- 3636
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Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6)Singh, Sheo B. / Kaelin, David E. / Wu, Jin et al. | 2015
- 3644
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Discovery, design, and synthesis of indole-based EZH2 inhibitorsGehling, Victor S. / Vaswani, Rishi G. / Nasveschuk, Christopher G. et al. | 2015
- 3650
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Synthesis and anti-tubercular activity of 2-nitroimidazooxazines with modification at the C-7 position as PA-824 analogsKang, Young-Goo / Park, Chan-Yong / Shin, Hongsuk et al. | 2015
- 3654
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3-Hydroxy-4-pyridinone derivatives designed for fluorescence studies to determine interaction with amyloid protein as well as cell permeabilityTelpoukhovskaia, Maria A. / Cawthray, Jacqueline F. / Rodríguez-Rodríguez, Cristina et al. | 2015
- 3658
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Cell-free expression with the toxic amino acid canavanineWorst, Emanuel G. / Exner, Matthias P. / De Simone, Alessandro et al. | 2015
- 3661
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Biarylsulfonamide CCR9 inhibitors for inflammatory bowel diseaseZhang, Jing / Romero, Jan / Chan, Audrey et al. | 2015
- 3665
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Discovery of a 6-(pyridin-3-yl)benzo[d]thiazole template for optimization of hedgehog and PI3K/AKT/mTOR dual inhibitorsYang, Zhaohui / Ma, Haikuo / Sun, Zhijian et al. | 2015
- 3671
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Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screeningDoddaramappa, Shridevi D. / Lokanatha Rai, K.M. / Srikantamurthy, Ningaiah et al. | 2015
- 3676
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Discovery of non-competitive thrombin inhibitor derived from competitive tryptase inhibitor skeleton: Shift in molecular recognition resulted from skeletal conversion of carboxylate into phosphonateAoyama, Hiroshi / Ijuin, Ryosuke / Kato, Jun-ya et al. | 2015
- 3681
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AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamideSatam, Vijay / Babu, Balaji / Patil, Pravin et al. | 2015
- 3686
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New geranylated flavanones from the fruits of Paulownia catalpifolia Gong Tong with their anti-proliferative activity on lung cancer cells A549Gao, Tian-yang / Jin, Xing / Tang, Wen-zhao et al. | 2015
- 3690
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Structure–activity relationship of N-benzenesulfonyl matrinic acid derivatives as a novel class of coxsackievirus B3 inhibitorsWang, Sheng-Gang / Kong, Lan-Ying / Li, Ying-Hong et al. | 2015
- 3694
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Synthesis and biological evaluation of N-cyclopropylbenzamide-benzophenone hybrids as novel and selective p38 mitogen activated protein kinase (MAPK) inhibitorsHeo, Jinyuk / Shin, Hanbo / Lee, Jun et al. | 2015
- 3699
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Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu2+ mediated DNA-targeting antibacterial agentsZhang, Ling / Kumar, Kannekanti Vijaya / Geng, Rong-Xia et al. | 2015
- 3706
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Design and synthesis of constrained analogs of LCRF-0004 as potent RON tyrosine kinase inhibitorsRaeppel, Stéphane L. / Therrien, Eric / Raeppel, Franck et al. | 2015
- 3711
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Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitorsBoucle, Sebastien / Tao, Sijia / Amblard, Franck et al. | 2015
- 3716
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Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activitiesNair, Padma / Yamamoto, Takashi / Cowell, Scott et al. | 2015
- 3721
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Exploration on natural product anibamine side chain modification toward development of novel CCR5 antagonists and potential anti-prostate cancer agentsXu, Guoyan G. / Zaidi, Saheem A. / Zhang, Feng et al. | 2015
- 3726
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Synthesis and cytotoxic activities of 2-substituted (25R)-spirostan-1,4,6-triene-3-ones via ring-opening/elimination and ‘click’ strategyLu, Xiao-Feng / Yang, Zheng / Huang, Nian-Yu et al. | 2015
- 3730
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Design, synthesis and evaluation of benzotriazole derivatives as novel antifungal agentsShah, Jay J. / Khedkar, Vijay / Coutinho, Evans C. et al. | 2015
- 3738
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Discovery of 2-arylamino-4-(1-methyl-3-isopropylsulfonyl-4-pyrazol-amino)pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitorsZhang, Peilong / Dong, Jiaqiang / Zhong, Boyu et al. | 2015
- 3744
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Dendritic hexadecapeptide as a cathepsin B degradable carrier for delivery of HSP90 inhibitorKolhatkar, Vidula / Suárez, Jose / Kolhatkar, Rohit et al. | 2015
- 3748
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Discovery of a novel 2,3,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinoline-1,4(6H)-dione series promoting neurogenesis of human neural progenitor cellsLin, Hong / Fang, Haiyan / Wang, Jamie et al. | 2015
- 3754
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Corrigendum to “Synthesis and cytotoxicity of 3,4-disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and novel 5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives bearing 3,4,5-trimethoxyphenyl moiety” [Bioorg. Med. Chem. Lett. 22/13 (2012) 4471–4474]Zhao, Pei-Liang / Duan, An-Na / Zou, Min et al. | 2015
- 3755
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Corrigendum to “Development of methyl isoxazoleazepines as inhibitors of BET” [Bioorg. Med. Chem. Lett. 25/9 (2015) 1842–1848]Hewitt, Michael C. / Leblanc, Yves / Gehling, Victor S. et al. | 2015
- IFC
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Editorial board| 2015