Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 4559
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Evolution of physicochemical properties of melanin concentrating hormone receptor 1 (MCHr1) antagonistsJohansson, Anders et al. | 2016
- 4565
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Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A proteaseKataoka, Hiroki / Ohe, Tomoyuki / Takahashi, Kyoko et al. | 2016
- 4568
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Rapid nuclear import of short nucleic acidsKitagawa, Mai / Okamoto, Akimitsu et al. | 2016
- 4571
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Gallic acid induces apoptosis in EGFR-mutant non-small cell lung cancers by accelerating EGFR turnoverNam, Boas / Rho, Jin Kyung / Shin, Dong-Myung et al. | 2016
- 4576
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Synthesis and biological evaluation of Hederacolchiside A1 derivatives as anticancer agentsFang, Yuanying / Yang, Zunhua / Ouyang, Hui et al. | 2016
- 4580
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Synthesis, antitumor evaluation and 3D-QSAR studies of [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivativesXu, Feng / Yang, Zhen-zhen / Ke, Zhong-lu et al. | 2016
- 4587
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In vitro and in vivo inhibitory activity of 6-amino-2,4,5-trimethylpyridin-3-ols against inflammatory bowel diseaseBanskota, Suhrid / Kang, Han-eol / Kim, Dong-Guk et al. | 2016
- 4592
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6′-O-Caffeoyldihydrosyringin isolated from Aster glehni suppresses lipopolysaccharide-induced iNOS, COX-2, TNF-α, IL-1β and IL-6 expression via NF-κB and AP-1 inactivation in RAW 264.7 macrophagesSeo, Seunghwan / Lee, Kyoung-Goo / Shin, Ji-Sun et al. | 2016
- 4599
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2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidaseNel, Magdalena S. / Petzer, Anél / Petzer, Jacobus P. et al. | 2016
- 4606
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Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitorsGarton, Neil S. / Barker, Michael D. / Davis, Rob P. et al. | 2016
- 4613
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Dual action Smac mimetics–zinc chelators as pro-apoptotic antitumoral agentsManzoni, Leonardo / Gornati, Davide / Manzotti, Mattia et al. | 2016
- 4620
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Quassinoids: Viral protein R inhibitors from Picrasma javanica bark collected in Myanmar for HIV infectionWin, Nwet Nwet / Ito, Takuya / Win, Yi Yi et al. | 2016
- 4625
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Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-ones as potent PLK4 inhibitors with oral antitumor efficacyLi, Sze-Wan / Liu, Yong / Sampson, Peter B. et al. | 2016
- 4631
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A novel lead of P-selectin inhibitor: Discovery, synthesis, bioassays and action mechanismWu, Jianhui / Zhao, Ming / Wang, Yuji et al. | 2016
- 4637
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Optimization of the choline transporter (CHT) inhibitor ML352: Development of VU6001221, an improved in vivo tool compoundBertron, Jeanette L. / Ennis, Elizabeth A. / Tarr, Christopher J. et al. | 2016
- 4641
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Hydrogen peroxide derived from marine peroxy sesquiterpenoids induces apoptosis in HCT116 human colon cancer cellsMiyazato, Haruna / Taira, Junsei / Ueda, Katsuhiro et al. | 2016
- 4645
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Pharbilignan C induces apoptosis through a mitochondria-mediated intrinsic pathway in human breast cancer cellsPark, Yong Joo / Choi, Chang-Ik / Chung, Kyu Hyuck et al. | 2016
- 4650
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Synthesis and biological evaluation of the codrug of Leonurine and Aspirin as cardioprotective agentsGao, Huan / Yang, Xiaohong / Gu, Xianfeng et al. | 2016
- 4655
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Anti-adipogenic and anti-diabetic effects of cis-3′,4′-diisovalerylkhellactone isolated from Peucedanum japonicum Thunb leaves in vitroChoi, Ra-Yeong / Nam, Sang-Jip / Ham, Ju Ri et al. | 2016
- 4661
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Synthesis and biological activities of novel 5-substituted-1,3,4-oxadiazole Mannich bases and bis-Mannich bases as ketol-acid reductoisomerase inhibitorsZhang, Yan / Liu, Xing-Hai / Zhan, Yi-Zhou et al. | 2016
- 4666
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Synthesis and antitumor activity evaluation of quinazoline derivatives bearing piperazine-1-carbodithioate moiety at C4-positionZhang, Ying / Yang, Chao-Rui / Tang, Xue et al. | 2016
- 4671
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Water-soluble extract of Saxifraga stolonifera has anti-tumor effects on Lewis lung carcinoma-bearing miceLiu, Dong / Yang, Ping / Zhang, Yu-Qing et al. | 2016
- 4679
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Design, synthesis and in vitro evaluation of amidoximes as histone deacetylase inhibitors for cancer therapyJiao, Peifu / Jin, Peng / Li, Chencan et al. | 2016
- 4684
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Benzo[b]thiophene-2-carboxamide derivatives as potent urotensin-II receptor antagonistsLim, Chae Jo / Woo, Seong Eun / Ko, Su Ik et al. | 2016
- 4687
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New labdane diterpenoids from Croton laui and their anti-inflammatory activitiesYang, Li / Zhang, Yu-Bo / Chen, Li-Feng et al. | 2016
- 4692
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Lipoic acid functionalized amino acids cationic lipids as gene vectorsSu, Rong-Chuan / Liu, Qiang / Yi, Wen-Jing et al. | 2016
- 4698
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Optimization of amino acid thioesters as inhibitors of metallo-β-lactamase L1Liu, Xiao-Long / Yang, Ke-Wu / Zhang, Yue-Juan et al. | 2016
- 4702
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Insights into the structure–activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A role played by the lactone moietyQiu, Haibo / Qian, Shan / Head, Sarah A. et al. | 2016
- 4705
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DNA-binding studies of the natural β-carboline eudistomin UGiulietti, Jennifer M. / Tate, Patrick M. / Cai, Ang et al. | 2016
- 4709
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One pot Click chemistry: A three component reaction for the synthesis of 2-mercaptobenzimidazole linked coumarinyl triazoles as anti-tubercular agentsAnand, Ashish / Kulkarni, Manohar V. / Joshi, Shrinivas D. et al. | 2016
- 4714
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Potent selective monoamine oxidase B inhibition by maackiain, a pterocarpan from the roots of Sophora flavescensLee, Hyun Woo / Ryu, Hyung Won / Kang, Myung-Gyun et al. | 2016
- 4720
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Wnt/β-catenin signaling plays an important role in the protective effects of FDP-Sr against oxidative stress induced apoptosis in MC3T3-E1 cellQi, Huan-Huan / Bao, Jun / Zhang, Qi et al. | 2016
- 4724
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Imaging human melanoma using a novel Tc-99m-labeled lactam bridge-cyclized alpha-MSH peptideLiu, Liqin / Xu, Jingli / Yang, Jianquan et al. | 2016
- 4729
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Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitorsFairhurst, Robin A. / Caravatti, Giorgio / Guagnano, Vito et al. | 2016
- 4735
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Three new alkaloids from Veratrum grandiflorum Loes with inhibition activities on Hedgehog pathwayGao, Lijuan / Chen, Fengyang / Li, Xiaoyu et al. | 2016
- 4739
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Discovery of novel 5-hydroxy-4-pyridone-3-carboxy acids as potent inhibitors of influenza Cap-dependent endonucleaseMiyagawa, Masayoshi / Akiyama, Toshiyuki / Mikamiyama-Iwata, Minako et al. | 2016
- 4743
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Benzimidazole analogs as WTA biosynthesis inhibitors targeting methicillin resistant Staphylococcus aureusYang, Shu-Wei / Pan, Jianping / Yang, Christine et al. | 2016
- 4748
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Indole-based allosteric inhibitors of HIV-1 integrasePatel, Pratiq A. / Kvaratskhelia, Nina / Mansour, Yara et al. | 2016
- 4753
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Facile synthesis of autophagonizer and evaluation of its activity to induce autophagic cell death in apoptosis-defective cell lineNguyen, Jennifer / Chen, Luxi / Kumar, Dhiraj et al. | 2016
- 4757
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Structure–activity relationship of novel series of 1,5-disubstituted tetrazoles as cyclooxygenase-2 inhibitors: Design, synthesis, bioassay screening and molecular docking studiesJawabrah Al-Hourani, Baker / Al-Awaida, Wajdy / Matalka, Khalid Z. et al. | 2016
- 4763
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Synthesis of novel 25-hydroxyprotopanaxadiol derivatives by methylation and methoxycarbonylation using dimethyl carbonate as a environment-friendly reagent and their anti-tumor evaluationGuo, Junhui / Xu, Zhe / Liu, Yafei et al. | 2016
- 4769
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Structural determinants of diphenethylamines for interaction with the κ opioid receptor: Synthesis, pharmacology and molecular modeling studiesGuerrieri, Elena / Bermudez, Marcel / Wolber, Gerhard et al. | 2016
- 4775
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Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clusteringGu, Chungang / Lamb, Michelle L. / Johannes, Jeffrey W. et al. | 2016
- 4781
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The discovery and preclinical characterization of 6-chloro-N-(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonistsRech, Jason C. / Bhattacharya, Anindya / Branstetter, Bryan J. et al. | 2016
- 4785
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Bioactive diterpenoids from Trigonostemon chinensis: Structures, NO inhibitory activities, and interactions with iNOSXu, Jing / Peng, Maoqin / Sun, Xiaocong et al. | 2016
- 4790
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Development of single and mixed isoform selectivity PI3Kδ inhibitors by targeting Asn836 of PI3KδMiller, Michelle S. / Mountford, Simon J. / Pinson, Jo-Anne et al. | 2016
- 4795
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Identification of a benzo imidazole thiazole derivative as the specific irreversible inhibitor of protein tyrosine phosphataseGe, Lin / Li, Kang-shuai / Li, Meng-meng et al. | 2016
- 4799
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Synthesis and hypoglycemic activity of 9-O-(lipophilic group substituted) berberine derivativesZhang, Shanshan / Wang, Xiaohong / Yin, Weicheng et al. | 2016
- 4804
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Role of a gitogenin-type steroidal saponin (3-O-β-d-glucopyranosyl (1→2)-β-d-glucopyranosyl (1→4)-β-d-galactopyranoside-25R,5α-spirostane-2α,3β-diol), isolated from the leaves of Malvastrum coromandelianum in regulating thyrotoxicosis in ratsPanda, Sunanda / Kar, Anand et al. | 2016
- 4808
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Synthesis and antinociceptive activity of new 2-substituted 4-(trifluoromethyl)-5,6-dihydrobenzo[h]quinazolinesBonacorso, Helio G. / Rosa, Wilian C. / Oliveira, Sara M. et al. | 2016
- 4815
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Synthesis, biological evaluation and molecular modeling study of some new methoxylated 2-benzylthio-quinazoline-4(3H)-ones as nonclassical antifolatesEl-Messery, Shahenda M. / Hassan, Ghada S. / Nagi, Mahmoud N. et al. | 2016
- 4824
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Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitorsKuklish, Steven L. / Antonysamy, Stephen / Bhattachar, Shobha N. et al. | 2016
- 4829
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Synthesis of novel nicotinohydrazide and (1,3,4-oxadiazol-2-yl)-6-(trifluoromethyl)pyridine derivatives as potential anticancer agentsNaresh Kumar, R. / Poornachandra, Y. / Nagender, P. et al. | 2016
- 4832
-
Spirobisnaphthalenes and lactones from the seeds of Strychnos angustiflora with potential anti-inflammatory activityJiang, Hua / Ma, Shuang-Gang / Li, Yong et al. | 2016
- 4837
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Discovery of a novel class of highly potent inhibitors of the p53–MDM2 interaction by structure-based design starting from a conformational argumentFuret, Pascal / Masuya, Keiichi / Kallen, Joerg et al. | 2016
- 4842
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Synthesis and biological evaluation of novel tricyclic oxazine and oxazepine fused quinazolines. Part 2: Gefitinib analogsSun, Min / Zhao, Jun / Chen, Xiangfeng et al. | 2016
- 4846
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Parallel inhibition of amino acid efflux and growth of erythrocytic Plasmodium falciparum by mefloquine and non-piperidine analogs: Implication for the mechanism of antimalarial actionGhavami, Maryam / Dapper, Christie H. / Dalal, Seema et al. | 2016
- 4851
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Substituted tetracyclic indole core derivatives of HCV NS5A inhibitor MK-8742Yu, Wensheng / Zhou, Guowei / Coburn, Craig A. et al. | 2016
- 4857
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Radiosynthesis and preliminary PET evaluation of 18F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptorsYuan, Gengyang / Jones, Graham B. / Vasdev, Neil et al. | 2016
- 4861
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Photo-controlled binding of MutS to photo-caged DNA duplexes incorporating 4-O-(2-nitrobenzyl) or 4-O-[2-(2-nitrophenyl)propyl]thymidineSeio, Kohji / Ohno, Yurie / Ohno, Kentaro et al. | 2016
- IFC
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Editorial board| 2016