Bioorganic and Medicinal Chemistry Letters
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
Table of contents
- 5653
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Graphical contents list| 2011
- 5673
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Strategies to improve in vivo toxicology outcomes for basic candidate drug moleculesLuker, Tim / Alcaraz, Lilian / Chohan, Kamaldeep K. et al. | 2011
- 5680
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Sulfonamides as selective oestrogen receptor β agonistsRoberts, Lee R. / Armor, Duncan / Barker, Carolyn et al. | 2011
- 5680
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Sulfonamides as selective oestrogen receptor b agonistsRoberts, L. R. / Armor, D. / Barker, C. et al. | 2011
- 5684
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Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stabilityJohnson, Patrick S. / Ryckmans, Thomas / Bryans, Justin et al. | 2011
- 5688
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Cellular uptake of Aib-containing amphipathic helix peptideWada, Shun-ichi / Tsuda, Hirokazu / Okada, Terumi et al. | 2011
- 5692
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Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: From systemic to liver-targeting inhibitorsRamtohul, Yeeman K. / Powell, David / Leclerc, Jean-Philippe et al. | 2011
- 5697
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Mannich reaction derivatives of novobiocin with modulated physiochemical properties and their antibacterial activitiesTambo-ong, Arlyn / Chopra, Sidharth / Glaser, Bryan T. et al. | 2011
- 5701
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Discovery of inhibitors of plasminogen activator inhibitor-1: Structure–activity study of 5-nitro-2-phenoxybenzoic acid derivativesPandya, Vrajesh / Jain, Mukul / Chakrabarti, Ganes et al. | 2011
- 5707
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Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N′-(methoxyphenylalkyl)piperazine σ1 receptor ligandsMoussa, Iman A. / Banister, Samuel D. / Akladios, Fady N. et al. | 2011
- 5707
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Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-Nprime-(methoxyphenylalkyl)piperazine 1 receptor ligandsMoussa, I. A. / Banister, S. D. / Akladios, F. N. et al. | 2011
- 5711
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Towards rational design of cannabinoid receptor 1 (CB1) antagonists for peripheral selectivityFulp, Alan / Bortoff, Katherine / Zhang, Yanan et al. | 2011
- 5715
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Coprismycins A and B, neuroprotective phenylpyridines from the dung beetle-associated bacterium, Streptomyces sp.Kim, Seong-Hwan / Ko, Hyeonseok / Bang, Hea-Son et al. | 2011
- 5719
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Synthesis of deuterium labeled ketamine metabolite dehydronorketamine-d 4Sulake, Rohidas S. / Chen, Chinpiao / Lin, Huei-Ru et al. | 2011
- 5722
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Synthesis and antigastric ulcer activity of novel 5-isoproyl-3,8-dimethylazulene derivativesZhang, Lu-Yun / Yang, Fang / Shi, Wan-Qi et al. | 2011
- 5726
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Synthesis and biological evaluation of α,β-unsaturated lactones as potent immunosuppressive agentsLee, Sun-Mi / Lee, Won-Gil / Kim, Young-Chul et al. | 2011
- 5726
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Synthesis and biological evaluation of a,b-unsaturated lactones as potent immunosuppressive agentsLee, S. M. / Lee, W. G. / Kim, Y. C. et al. | 2011
- 5730
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Design, synthesis and anticancer activity of novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivativesKang, Jin-Ah / Yang, Zunhua / Lee, Ji Yeon et al. | 2011
- 5735
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2,5-Disubstituted-1,3,4-oxadiazoles/thiadiazole as surface recognition moiety: Design and synthesis of novel hydroxamic acid based histone deacetylase inhibitorsRajak, Harish / Agarawal, Avantika / Parmar, Poonam et al. | 2011
- 5739
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Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screeningXia, Guangxin / Xue, Mengzhu / Liu, Lin et al. | 2011
- 5739
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Potent and novel 11b-HSD1 inhibitors identified from shape and docking based virtual screeningXia, G. / Xue, M. / Liu, L. et al. | 2011
- 5745
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Design and synthesis of C35-fluorinated solamins and their growth inhibitory activities against human cancer cell linesKojima, Naoto / Suga, Yuki / Hayashi, Hiromi et al. | 2011
- 5750
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Enhanced ROS production and cell death through combined photo- and sono-activation of conventional photosensitising drugsMcCaughan, Bridgeen / Rouanet, Claire / Fowley, Colin et al. | 2011
- 5753
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Identification of novel BRAF kinase inhibitors with structure-based virtual screeningPark, Hwangseo / Choi, Hwanho / Hong, Seunghee et al. | 2011
- 5757
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Improved synthesis and biological evaluation of chelator-modified α-MSH analogs prepared by copper-free click chemistryBaumhover, Nicholas J. / Martin, Molly E. / Parameswarappa, Sharavathi G. et al. | 2011
- 5757
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Improved synthesis and biological evaluation of chelator-modified a-MSH analogs prepared by copper-free click chemistryBaumhover, N. J. / Martin, M. E. / Parameswarappa, S. G. et al. | 2011
- 5762
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d(TGGGAG) with 5′-nucleobase-attached large hydrophobic groups as potent inhibitors for HIV-1 envelop proteins mediated cell–cell fusionChen, Wei / Xu, Liang / Cai, Lifeng et al. | 2011
- 5762
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d(TGGGAG) with 5prime-nucleobase-attached large hydrophobic groups as potent inhibitors for HIV-1 envelop proteins mediated cell-cell fusionChen, W. / Xu, L. / Cai, L. et al. | 2011
- 5765
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Synthesis and evaluation of 1-(4-[18F]fluoroethyl)-7-(4′-methyl)curcumin with improved brain permeability for β-amyloid plaque imagingLee, Iljung / Yang, Jehoon / Lee, Jung Hee et al. | 2011
- 5765
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Synthesis and evaluation of 1-(4-[18F]fluoroethyl)-7-(4prime-methyl)curcumin with improved brain permeability for b-amyloid plaque imagingLee, I. / Yang, J. / Lee, J. H. et al. | 2011
- 5770
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Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivativeDevji, Tehsina / Reddy, Claire / Woo, Christina et al. | 2011
- 5774
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Structure–activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activatorsXing, Xuechao / Chang, Ling-Chu / Kong, Qiongman et al. | 2011
- 5778
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Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug designMiura, Takaaki / Fukami, Takaaki A. / Hasegawa, Kiyoshi et al. | 2011
- 5784
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Microbial metabolism. Part 13. Metabolites of hesperetinHerath, Wimal / Khan, Ikhlas Ahmad et al. | 2011
- 5787
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Synthesis, structure–activity relationship and in vitro biological evaluation of N-arylethyl isoquinoline derivatives as Coxsackievirus B3 inhibitorsWang, Yan-Xiang / Li, Yu-Huan / Li, Ying-Hong et al. | 2011
- 5791
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Design, synthesis and structure–activity relationship of novel [3.3.1] bicyclic sulfonamide-pyrazoles as potent γ-secretase inhibitorsAubele, Danielle L. / Truong, Anh P. / Dressen, Darren B. et al. | 2011
- 5791
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Design, synthesis and structure-activity relationship of novel [3.3.1] bicyclic sulfonamide-pyrazoles as potent g-secretase inhibitorsAubele, D. L. / Truong, A. P. / Dressen, D. B. et al. | 2011
- 5795
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Synthesis of a series of γ-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonistsMüller, Andreas / Höfner, Georg / Renukappa-Gutke, Thejavathi et al. | 2011
- 5795
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Synthesis of a series of g-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonistsMuller, A. / Hofner, G. / Renukappa-Gutke, T. et al. | 2011
- 5800
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Synthesis and anticonvulsant activity of new 1-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-dionesKamiński, Krzysztof / Rzepka, Sabina / Obniska, Jolanta et al. | 2011
- 5804
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Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivativesShi, Xue-Liang / Ge, Jian-Feng / Liu, Bao-Qiang et al. | 2011
- 5808
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Synthesis of β-functionalized Temoporfin derivatives for an application in photodynamic therapyAicher, Daniel / Gräfe, Susanna / Stark, Christian B.W. et al. | 2011
- 5808
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Synthesis of b-functionalized Temoporfin derivatives for an application in photodynamic therapyAicher, D. / Grafe, S. / Stark, C. B. et al. | 2011
- 5812
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Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitorsMotiwala, Hashim / Kandre, Shivaji / Birar, Vishal et al. | 2011
- 5818
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Synthesis and evaluation of ferrocenoyl pentapeptide (Fc-KLVFF) as an inhibitor of Alzheimer's Ab1-42 fibril formation in vitroWei, C. W. / Peng, Y. / Zhang, L. et al. | 2011
- 5818
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Synthesis and evaluation of ferrocenoyl pentapeptide (Fc-KLVFF) as an inhibitor of Alzheimer’s Aβ1–42 fibril formation in vitroWei, Chuan-Wan / Peng, Yong / Zhang, Lin et al. | 2011
- 5822
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Synthesis and acrosin inhibitory activities of substituted ethyl 5-(4-aminophenyl)-1H-pyrazole-3-carboxylate derivativesQi, Jingjing / Zhu, Ju / Liu, Xuefei et al. | 2011
- 5826
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Design and synthesis of long acting inhaled corticosteroids for the treatment of asthmaMillan, David S. / Ballard, Stephen A. / Chunn, Sara et al. | 2011
- 5831
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Anti-AIDS agents 87. New bio-isosteric dicamphanoyl-dihydropyranochromone (DCP) and dicamphanoyl-khellactone (DCK) analogues with potent anti-HIV activityLiu, Hong-Shan / Xu, Shi-Qing / Cheng, Ming et al. | 2011
- 5835
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Solid-phase synthesis and pharmacological evaluation of novel nucleoside-tethered dinuclear platinum(II) complexesD’Errico, Stefano / Oliviero, Giorgia / Piccialli, Vincenzo et al. | 2011
- 5839
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Hydrazidomycins, cytotoxic alkylhydrazides from Streptomyces atratusUeberschaar, Nico / Ndejouong, Basile Le Sage Tchize / Ding, Ling et al. | 2011
- 5842
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Synthesis and evaluation of compounds that induce readthrough of premature termination codonsJung, Michael E. / Ku, Jin-Mo / Du, Liutao et al. | 2011
- 5849
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Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activitiesSun, Xicheng / Qiu, Jian / Strong, Sarah A. et al. | 2011
- 5854
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Synthesis of a new trifluoromethylketone analogue of l-arginine and contrasting inhibitory activity against human arginase I and histone deacetylase 8Ilies, Monica / Dowling, Daniel P. / Lombardi, Patrick M. et al. | 2011
- 5859
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Design and evaluation of a novel fluorescent CB2 ligand as probe for receptor visualization in immune cellsPetrov, Ravil R. / Ferrini, Maria E. / Jaffar, Zeina et al. | 2011
- 5863
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Simple synthetic toll-like receptor 2 ligandsAbdel-Aal, Abu-Baker M. / Al-Isae, Kalifa / Zaman, Mehfuz et al. | 2011
- 5866
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Metal-free cleavage efficiency toward DNA by a novel PNA analog-bridged macrocyclic polyamineWang, Ming-Qi / Zhang, Ji / Zhang, Yu et al. | 2011
- 5870
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Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitorsZeng, Hongbo / Belanger, David B. / Curran, Patrick J. et al. | 2011
- 5876
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Ursolic acid is a PPAR-α agonist that regulates hepatic lipid metabolismJia, Yaoyao / Bhuiyan, Muhammad Javidul Haque / Jun, Hee-jin et al. | 2011
- 5876
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Ursolic acid is a PPAR-a agonist that regulates hepatic lipid metabolismJia, Y. / Bhuiyan, M. J. / Jun, H. j. et al. | 2011
- 5881
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Development of 2-substituted-N-(naphth-1-ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and Ab-aggregation inhibitors: Synthesis and biological evaluationMohamed, T. / Yeung, J. C. / Rao, P. P. et al. | 2011
- 5881
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Development of 2-substituted-N-(naphth-1-ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and Aβ-aggregation inhibitors: Synthesis and biological evaluationMohamed, Tarek / Yeung, Jacky C.K. / Rao, Praveen P.N. et al. | 2011
- 5888
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Fuscoside E: A strong anti-inflammatory diterpene from Caribbean octocoral Eunicea fuscaReina, Eduardo / Puentes, Carlos / Rojas, Juan et al. | 2011
- 5892
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Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and IIKnaus, Edward E. / Innocenti, Alessio / Scozzafava, Andrea et al. | 2011
- 5897
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Synthesis and in-vitro anticancer activity of 3,5-bis(indolyl)-1,2,4-thiadiazolesKumar, Dalip / Kumar, N. Maruthi / Chang, Kuei-Hua et al. | 2011
- 5901
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In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin AIshimoto, Hidekazu / Shibata, Mari / Myojin, Yuki et al. | 2011
- 5905
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Synthesis of a quinazoline derivative: A new α1-adrenoceptor ligand for conjugation to quantum dots to study α1-adrenoceptors in living cellsZhou, Guoheng / Wang, Lei / Ma, Yudao et al. | 2011
- 5905
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Synthesis of a quinazoline derivative: A new a1-adrenoceptor ligand for conjugation to quantum dots to study a1-adrenoceptors in living cellsZhou, G. / Wang, L. / Ma, Y. et al. | 2011
- 5910
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Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockersWoo, Hyun Min / Lee, Yun Suk / Roh, Eun Joo et al. | 2011
- 5916
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MDM2-p53 protein–protein interaction inhibitors: A-ring substituted isoindolinonesWatson, Anna F. / Liu, Junfeng / Bennaceur, Karim et al. | 2011
- 5920
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Histone deacetylase activators: N-acetylthioureas serve as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrateSingh, Raushan K. / Mandal, Tanmay / Balsubramanian, Narayanaganesh et al. | 2011
- 5924
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Discovery of BI 99179, a potent and selective inhibitor of type I fatty acid synthase with central exposureKley, Jörg T. / Mack, Jürgen / Hamilton, Bradford et al. | 2011
- 5928
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Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cellsRadi, Marco / Brullo, Chiara / Crespan, Emmanuele et al. | 2011
- 5934
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Synthesis and evaluation of furoxan-based nitric oxide-releasing derivatives of tetrahydroisoquinoline as anticancer and multidrug resistance reversal agentsZou, Zhi-hong / Lan, Xiao-bu / Qian, Hai et al. | 2011
- 5939
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Discovery of a highly potent series of TLR7 agonistsJones, Peter / Pryde, David C. / Tran, Thien-Duc et al. | 2011
- 5944
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New betulinic acid derivatives as potent proteasome inhibitorsQian, Keduo / Kim, Sang-Yong / Hung, Hsin-Yi et al. | 2011
- 5948
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Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3bCociorva, O. M. / Li, B. / Nomanbhoy, T. et al. | 2011
- 5948
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Synthesis and structure–activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3βCociorva, Oana M. / Li, Bei / Nomanbhoy, Tyzoon et al. | 2011
- 5952
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Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitorsNi, Yike / Gopalsamy, Ariamala / Cole, Derek et al. | 2011
- 5957
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Pyrrolidin-3-yl-N-methylbenzamides as potent histamine 3 receptor antagonistsZhou, Dahui / Gross, Jonathan L. / Sze, Jean Y. et al. | 2011
- 5961
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Preparation and antibacterial evaluation of decarboxylated fluoroquinolonesNguyen, Son T. / Ding, Xiaoyuan / Butler, Michelle M. et al. | 2011
- 5964
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3D QSAR and docking study of flavone derivatives as potent inhibitors of influenza H1N1 virus neuraminidaseGao, Li / Zu, Mian / Wu, Song et al. | 2011
- 5971
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RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptorKrysko, Andrei A. / Samoylenko, Georgiy V. / Polishchuk, Pavel G. et al. | 2011
- 5975
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Synthesis and cytotoxicity of 8-cyano-3-substitutedalkyl-5-methyl-4-methylene-7-methoxy-3,4-dihydropyrido[4,3-d]pyrimidinesMo, Wen-Yan / Liang, Yong-Ju / Gu, Yu-Cheng et al. | 2011
- 5978
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Synthesis of phenanthroindolizidine alkaloids and evaluation of their antitumor activities and toxicitiesIkeda, Takashi / Yaegashi, Takashi / Matsuzaki, Takeshi et al. | 2011
- 5982
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Constructing transferrin receptor targeted drug delivery system by using doxorubicin hydrochloride and vanadocene dichlorideZhang, Yanxia / Xiang, Junfeng / Liu, Yan et al. | 2011
- 5987
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Formation, recognition and bioactivities of a novel G-quadruplex in the STAT3 geneLin, Sen / Li, Sufang / Chen, Zan et al. | 2011
- 5992
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Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitorsSleebs, Brad E. / Nikolakopoulos, George / Street, Ian P. et al. | 2011
- 5995
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Inhibition of COX-1 activity and COX-2 expression by 3-(4′-geranyloxy-3′-methoxyphenyl)-2-trans propenoic acid and its semi-synthetic derivativesGenovese, Salvatore / Curini, Massimo / Gresele, Paolo et al. | 2011
- 5995
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Inhibition of COX-1 activity and COX-2 expression by 3-(4prime-geranyloxy-3prime-methoxyphenyl)-2-trans propenoic acid and its semi-synthetic derivativesGenovese, S. / Curini, M. / Gresele, P. et al. | 2011
- 5999
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Conformationally constrained analogs of BAY 59–3074 as novel cannabinoid receptor ligandsTeng, Heidi / Thakur, Ganesh A. / Makriyannis, Alexandros et al. | 2011
- 6003
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4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparumVerhaeghe, Pierre / Dumètre, Aurélien / Castera-Ducros, Caroline et al. | 2011
- 6007
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Dual pro-drugs of 2′-C-methyl guanosine monophosphate as potent and selective inhibitors of hepatitis C virusMcGuigan, Christopher / Madela, Karolina / Aljarah, Mohamed et al. | 2011
- 6007
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Dual pro-drugs of 2prime-C-methyl guanosine monophosphate as potent and selective inhibitors of hepatitis C virusMcGuigan, C. / Madela, K. / Aljarah, M. et al. | 2011
- 6013
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Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonistsBuzard, Daniel / Han, Sangdon / Thoresen, Lars et al. | 2011
- 6019
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Corrigendum to “Synthesis and antihistamine evaluations of novel loratadine analogues” [Bioorg. Med. Chem. Lett. 21 (2011) 4454–4456]Wang, Yue / Wang, Juan / Lin, Yan et al. | 2011
- 6020
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Corrigendum to “Synthesis and evaluation of indole-based new scaffolds for antimicrobial activities—Identification of promising candidates” [Bioorg. Med. Chem. Lett. 21 (2011) 3367–3372]Singh, Palwinder / Pooja / Yadav, Bhawna et al. | 2011
- IFC
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Editorial board| 2011