Using An Orthogonal Ligand-Receptor Pair to Control Endogenous Gene Expression In Mammalian Cell (English)
- New search for: Liang, J.
- New search for: McLachlan, M.
- New search for: Zhao, H.
- New search for: Liang, J.
- New search for: McLachlan, M.
- New search for: Zhao, H.
In:
Food, pharmaceutical and bioengineering
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386
;
2011
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ISBN:
- Conference paper / Print
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Title:Using An Orthogonal Ligand-Receptor Pair to Control Endogenous Gene Expression In Mammalian Cell
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Contributors:
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Conference:conference, Food, pharmaceutical and bioengineering ; 2011 ; Minneapolis, Minnesota
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Published in:
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Publisher:
- New search for: Curran
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Place of publication:New York
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Publication date:2011-01-01
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Size:386 pages
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Remarks:Includes bibliographical references and index
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ISBN:
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Type of media:Conference paper
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Type of material:Print
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Language:English
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Keywords:
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Source:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents conference proceedings
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1
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Engineering Anaerobic Gut Fungi for Lignocellulose Hydrolysis and Biofuel ProductionO Malley, M.A. / Theodorou, M.K. / Kaiser, C.A. et al. | 2011
- 2
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Engineering Carbon and Energy Metabolism for CHO Cells for Improved Productivity and Extended LifespanWilkens, C.A. / Gerdtzen, Z.P. et al. | 2011
- 5
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Exploring the Cre/Lox System for Targeted Integration Into the Human GenomeLanza, A.M. / Alper, H. et al. | 2011
- 6
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Enhancing Transient Gene Expression In CHOs Cells Through the Co-Transfection of the Product Gene and Bcl-XIZustiak, M.P. / Xie, Y. / Zhu, J. / Betenbaugh, M.J. et al. | 2011
- 7
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Using In-Situ Raman Spectroscpy to Determine Real-Time Growth and Metabolic Profiles During a Mammalian Cell Culture ProcessSmelko, J.P. et al. | 2011
- 8
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Effect of Endoplasmic Reticulum Stress On Protein Productivity In Recombinant CHO CellsPrashad, K. / Prabhakar, A. / Mehra, S. et al. | 2011
- 9
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Uncovering the Mechanisms of Methotrexate-Mediated DHFR Amplification In Chinese Hamster Ovary Cells Through Transcriptome AnalysisJacob, N.M. / Le, H. / Ng, S.W. / Loo, B.L.W. / Tsa, Y.-S. / Liu, Z. / Hu, W.-S. et al. | 2011
- 10
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A First Principles Based Structure Prediction Algorithm for Beta and Mixed Alpha/Beta ProteinsSubramani, A. / Wei, Y. / Floudas, C.A. et al. | 2011
- 12
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Hofmeister Effects On Sup35NM Amyloid Formation KineticsRubin, J. / Behrens, S.H. / Chernoff, Y.O. / Bommarius, A.S. et al. | 2011
- 13
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Peptide Probes for Rapid, Specific and Quantitative Detection of Distinct Beta Amyloid OligomersHu, Y. / Su, B. / Zheng, H.Q. / Ahn, J.H. / Kim, J.R. et al. | 2011
- 14
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Suppressing Protein Aggregation by Reducing Local Concentration FluctuationsRoberts, C.J. / Sahin, E. / Blanco, M.A. / Das, T.K. et al. | 2011
- 15
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Aromatic Peptides Selectively Target and Remodel Soluble Oligomers of AmyloidLadiwala, A.R.A. / Dordick, J.S. / Tessier, P.M. et al. | 2011
- 16
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Mammalian Cell-Based Methods Monitoring Protein Misfolding and AggregationGreogire, S. / Kwon, I. et al. | 2011
- 17
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Identification of Transthyretin Domains Involved with Binding to Beta-Amyloid: In Search of Nature's Anti-Alzheimer's `Drug'Du, J. / Cho, P.C. / Yang, D.T. / Murphy, R.M. et al. | 2011
- 18
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Fermentation Cost Improvement Through Propagation Advances for a Commercially Relevant Biomass-to-Ethanol ProcessSutton, K.B. / Emme, B. / Jones, L. / McHatton, S. / Kang, C. / Corbett, C. / Putnam, L. / Torry-Smith, M. et al. | 2011
- 19
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Combined Computational and Experimental Investigations of Processive Cellulases for Engineering Activity ImprovementsBeckham, G.T. / Taylor, L. / Crowley, M.F. / Adney, W.S. / Himmel, M.E. et al. | 2011
- 20
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Exploration of Significant Enzyme Activities Required for the Deconstruction of Ionic-Liquid Pretreated BiomassBarr, C.J. / Mertens, J. / Schall, C. et al. | 2011
- 21
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Inhibition of Enzymatic Hydrolysis by Soluble Sugars on Model Cellulose Thin Film Using Quartz Crystal MicrobalanceLi, H.-F. / Garlapalli, R. / Flythe, M.D. / Nokes, S.E. / Rankin, S.E. / Knutson, B.L. et al. | 2011
- 23
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Selection and Characterization of Acid-Stable Cellulases Against Pretreated Oil Palm Empty Fruit Bunch From a Colombian Extreme EnvironmentMedina, L.M. / Cabezas, L. / Bahamon, I. / Palma, L. / Gonzalez, A. / Restrepo, S. et al. | 2011
- 25
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Effect of AFEX Pretreatment Degradation Products On Enzymatic Hydrolysis and Microbial Fermentation by Saccharomyces Cerevisiae 424A(LNH-ST)Tang, X. / Da Costa Sousa, L. / Chundawat, S. / Jin, M. / Ming, L. / Humpula, J. / Uppugundla, N. / Chambliss, K. / Vismeh, R. / Jones, A.D. et al. | 2011
- 26
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Modelling Simultaneous Saccharification and Fermentation of Microcrystalline Cellulose Using Computational Fluid DynamicsVan Zyl, J.M. / Harms, T.M. / Van Rensburg, E. / Van Zyl, W.H. / Lynd, L.R. et al. | 2011
- 29
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Substrate Elasticity Regulates the Biophysical Properties of Hematopoietic Stem and Progenitor CellsChoi, J.S. / Leonard, T. / Harley, B.A. et al. | 2011
- 31
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Soluble Growth Factors Mediate Mesenchymal Stem Cell Migration to TumorsGhosh, D. / Dawson, M. et al. | 2011
- 32
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Mechanical Characterization of Adult Bone Marrow Stem Cells for Injection or ImplantationRibeiro, A.J.S. / Taylor, R.W.E. / Dahl, K.N. et al. | 2011
- 33
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Effects of Substrate Mechanics On Yield and Contractility of Cardiomyocytes Generated From Pluripotent Stem CellsHazeltine, L. / Simmons, C. / Salick, M. / Badur, M. / Wakatsuki, T. / Crone, W. / Pruitt, B. / Palecek, S. et al. | 2011
- 34
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Correlating Effect of Gel Microstructural Features with Specific Differentiation Patterning of Embryonic Stem CellsTask, K. / D Amore, A. / Singh, S. / Jaramillo, M. / Kumta, P. / Banerjee, I. et al. | 2011
- 36
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Monitoring the Effect of Mechanical Load On Fibronectin Conformation Using 3-D Magnetic TweezersChai, J. / Adhikari, A.S. / Chang, A.C. / Dunn, A.R. et al. | 2011
- 37
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The Polymorphs of ROY: Application of Crystal Structure Prediction TechniquesVasileiadis, M. / Kazantsev, A.V. / Karamertzanis, P.G. / Adjiman, C.S. / Pantelides, C.C. et al. | 2011
- 39
-
Spiral Growth Model for Organic Crystals of Real Complexity: How to Account for Unstable Spiral EdgesKuvadia, Z.B. / Doherty, M.F. et al. | 2011
- 40
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Modeling of Morphology Transformations In Crystalline Materials: A Generalized FrameworkSingh, M.R. / Borchert, C. / Sundmacher, K. / Ramkrishna, D. et al. | 2011
- 41
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Microfluidic Platform for Evaporation-Based Solid Form Screening of Pharmaceutical CompoundsGoyal, S. / Thorson, M.R. / Zarkhah, A.G. / Gong, Y. / Zhang, G.G.Z. / Zukoski, C.F. / Kenis, P.J.A. et al. | 2011
- 43
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Microfluidic Platforms for Crystallization Screening and In Situ Phasing & Structure Determination of ProteinsGuha, S. / Perry, S.L. / Pawate, A. / Nair, S.K. / Kenis, P.J.A. et al. | 2011
- 44
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Microfluidic Platforms for In Situ Crystallographic AnalysisPerry, S.L. / Guha, S. / Pawate, A. / Gennis, R.B. / Ren, Z. / Kenis, P.J.A. et al. | 2011
- 46
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Development and Optimization Process Deriving Fermentable Sugars From Lignocellulosic Application In Biofuels and ChemicalsParekh, S. et al. | 2011
- 47
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Application of Physiologically Based Pharmacokinetic Model for Drug DevelopmentZhou, H. / Lukacova, V. / Bolger, M. / Woltosz, W. et al. | 2011
- 48
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Chromatography Applications In the Purification of Whey ProteinsNg, P.K. et al. | 2011
- 49
-
Controlling Glycation Levels In Antibodies Produced In Fed-Batch Cell Culture ProcessesVarma, S. / Vijayasankaran, N. / Meier, S. et al. | 2011
- 50
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Use of Statistical Modeling Tools to Characterize the Design Space for a Late-Stage Mammalian Cell Culture ProcessLambropoulos, J. / Tescione, L. / Paranandi, R. / Quirk, R. / Woppmann, B. / Yusuf-Makagiansar, H. / Sinacore, M. / Ryll, T. et al. | 2011
- 51
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Proof-of-Concept of a Continuous-Flow Heck Coupling and HBr-Catalyzed Oxidation for Pharmaceutical Lab-Hood ManufacturingZaborenko, N. / Buser, J.Y. / McFarland, A.D. / Kjell, D.P. / Astleford, B.A. / Gu, R.L. et al. | 2011
- 52
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Correlating Powder Flowability to Particle Size Distribution Using Chemometric TechniquesBurcham, C.L. / Roginski, R.T. et al. | 2011
- 53
-
Optimization of API Attributes and Flow Properties Via Crystallization and Size Reduction TechniquesGrigorov, P. / Lekhal, A. / Zarkadas, D. et al. | 2011
- 55
-
Crystallization and Milling Development Enabling A High Drug Load FormulationHoffman, P. / Vicenzi, J. et al. | 2011
- 56
-
Analysis of Bayesian Linearity (BL) to Improve Performance for API to DP IntegrationEinstiene, A.I.C. et al. | 2011
- 57
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API Particle Engineering As a Strategy to Address Sticking/Picking During Drug Product DevelopmentMcDermott, T. / Sheikh, A. / Gandarilla, J. et al. | 2011
- 58
-
Utilizing Drop-On-Demand Printing In the Manufacture of Transdermal Dosage FormsBrown, M. et al. | 2011
- 59
-
API Excipient Co-Crystal Screen to Optimize Robustness of An Oral Solution Drug ProductLuthra, S. / Murphy, B. / Samas, B. / Krzyzaniak, J. et al. | 2011
- 60
-
Quality by Design (QbD) Opportunities, Challenges and Future DirectionNasr, M. et al. | 2011
- 61
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QbD - It's Not Just for Breakfast AnymoreCollins, P.C. et al. | 2011
- 62
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Challenges and Opportunities for Process Systems Engineering Approaches to QbD and Design SpaceReklaitis, G.V. et al. | 2011
- 64
-
Regulating Calcitonin-Like Receptor Signaling Through Transmembrane Domain InteractionsSu, P.-C. / Si, W. / Wu, J. / Berger, B.W. et al. | 2011
- 66
-
Spatiotemporal Membrane Organization At the Single Molecular Level During T Cell Receptor TriggeringRoh, K.-H. / Davis, M.M. et al. | 2011
- 67
-
Spatial Dynamics In Bacterial Signal TransductionWu, K. / Rao, C.V. et al. | 2011
- 68
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Investigation of the Residue Specific Interactions of A beta with Neuron-Like Cell Surface Molecules: Implications for the Mechanism of Pathogenesis of Alzheimer's DiseaseVenkatasubramaniam, A.K. / Good, T.A. et al. | 2011
- 70
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Stochastic Modeling of BMP Signaling Pathways Identifies Mechanisms of Noise Suppression In Cell SignalingKarim, M.S. / Buzzard, G.T. / Umulis, D.M. et al. | 2011
- 71
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Implication of Particle-Cell Dynamics In Physiological Blood Flow On the Efficacy of Vascular-Targeted Drug CarriersCharoenphol, P. / Eniola-Adefeso, O. et al. | 2011
- 73
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cAMP Stimulation Regulates Aquaporin-1 Mediated Transendothelial Water Transport In Bovine Aortic Endothelium MonolayersRaval, C.B. / Tarbell, J.M. / Jan, K.-M. / Rumschitzki, D.S. et al. | 2011
- 75
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Antibiotic Pumps In Bacteria Export Endocrine Disrupting Chemicals During Wastewater TreatmentLi, X. / Conroy-Ben, O. et al. | 2011
- 77
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Optimization of a Louisiana Native Algal Co-Culture for Biofuel ProductionBai, R. / Gutierrez-Wing, M.T. / Benton, M.G. / Rusch, K.A. et al. | 2011
- 78
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Controls of Microalgal Biomass and Lipid Production In Municipal Wastewater-Fed BioreactorsSturm, B.S.M. / Smith, V.H. / Fortier, M.-O. / Peltier, E. / Denoyelles, F.J. et al. | 2011
- 79
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Effects of Total Inorganic Carbon and Nitrogen Concentrations On Lipid Formation In Chlorella VulgarisKim, J. / Lee, J.-Y. / Siddiqui, K.F. et al. | 2011
- 81
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Medium Optimization for Enhanced Lipid Production by Chlorella Protothecoides UTEX25Cheng, K.-C. / Ren, M. / Ogden, K. et al. | 2011
- 82
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Single-Cell Growth Kinetics of Algae, Chlorela VulgarisDewan, A. / Kim, J. / Bithi, S.S. / Kerls, M. / Vanapalli, S.A. / Karim, M.N. et al. | 2011
- 84
-
Modeling and Optimization of Algae Based Biodiesel ProductionYadala, S. / Cremaschi, S. et al. | 2011
- 86
-
Enzymatic Reduction of Nitro Compounds to Amines with NitroreductasePark, J.T. / Bommarius, A.S. et al. | 2011
- 87
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How to Tie Peptide KnotsLink, A.J. et al. | 2011
- 88
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Implementation of Metabolic Engineering to Construct a Robust Platform for Resveratrol Production and Protein Engineering Study of Stilbene SynthaseBhan, N. / Lim, C.G. / Fowler, Z. / Hueller, T. / Schaffer, S. / Koffas, M.A.G. et al. | 2011
- 89
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Refactored Biosynthetic Pathways: Delineating Pathway Expression From Sophisticated Regulation Cascades Via Synthetic BiologyShao, Z. / Zhao, H. et al. | 2011
- 91
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Constructing Building Blocks for a Cell-Free Synthetic Pathway Biotransformation: A High Yield and Low-Cost Bio-Manufacturing PlatformMyung, S. / Zhang, Y.-H.P. et al. | 2011
- 92
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Engineering E. Coli Whole-Cell Catalysts for Consolidated Production of Lactic Acid From CellodextrinRutter, C. / Mathew, N. / Chen, R. et al. | 2011
- 93
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Inceasing Organic Acid Tolerance In CyanobacteriaBegemann, M.B. / Pfleger, B.F. et al. | 2011
- 94
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Extrinsic Growth Signals Driving Drosophila Imaginal Cell Proliferation In VitroZartman, J.J. / Restrepo, S. / Basler, K. et al. | 2011
- 95
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Gene Expression Profiling of Cd133^+ Prostate Cancer Stem Cells Induced from PC3 Carcinoma Cell Line CulturesPortillo-Lara, R. / Alvarez, M.M. et al. | 2011
- 104
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Breaking the Habit: Overcoming Acute Sensitivities of Antibody-Producing Mammalian Cell Lines to pH and Raw MaterialsJaluria, P. / Malanson, H. / Sorensen, E.T. / Kantardjieff, A. / Adams, D. et al. | 2011
- 105
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Process Characterization for Commercial Cell Culture ProcessVijayasankaran, N. / Calhoun, K. / Varma, S. / Winchester, A. / Meier, S. et al. | 2011
- 106
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Improved Process Development Based On Increased Understanding of MetabolismGilbert, A. / McElearney, K. / Kshirsagar, R. / Sinacore, M. / Ryll, T. et al. | 2011
- 107
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Effect of Operating Parameters On the Product Quality of Monoclonal AntibodySarenac, M. / Neunstoecklin, B. / Soos, M. / Morbidelli, M. et al. | 2011
- 108
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In Vitro Aggregation Behavior of a Lambda Light Chain Dimer Expressed In Mammalian CellsArosio, P. / Owczarz, M. / Muller-Spath, T. / Beeg, M. / Wu, H. / Salmona, M. / Morbidelli, M. et al. | 2011
- 109
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Mutagenesis of the Lasso Antibiotic Peptide Microcin J25: Discovery of Variants with Increased Potency and New Insights Into the Structure-Activity RelationshipPan, J.S.-J. / Link, A.J. et al. | 2011
- 110
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Deep Mutational Scanning As a New Tool for Protein Structure/Function RelationshipsWhitehead, T. et al. | 2011
- 111
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Broadly Protective Influenza Vaccines Based On the Conserved Hemagglutinin Stalk RegionLu, Y. / Welsh, J.P. / Swartz, J.R. et al. | 2011
- 112
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Designing Viral Capsid Nanoreactors for the Study of Compartmentalized ProcessesTullman-Ercek, D. / Glasgow, J. et al. | 2011
- 113
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Endothelial Modulation of Adiponectin Oligomer Transport and FunctionRutkowski, J.M. / Scherer, P.E. et al. | 2011
- 114
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Engineered, Peptide Binding Chaperones for Membrane Protein CrystallizationMaynard, J.A. / Pai, J.C. / Enztminger, K. / Lieberman, R.L. et al. | 2011
- 115
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Enhanced Affinity of An Insulin Degrading Enzyme Mutant towards InsulinCakir, B. / Kavakli, H. / Kizilel, S. et al. | 2011
- 116
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Practical Applications of QbD for a Parenteral Drug ProductHarper, N.J. / Koganti, V. / Ranade, G.R. et al. | 2011
- 119
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Rational Design and Scale-up of Batch Lubrication Processes for Immediate Release FormulationsKushner, J. / Blackwood, D.O. / Macdonald, B.C. / Polizzi, M. / Moore, F.M. / Hancock, B.C. et al. | 2011
- 120
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Automation and Control of Drug-On-Demand TechnologyHirshfield, L. / Giridhar, A. / Reklaitis, G.V. / Venkatasubramanian, V. / Harris, M.T. et al. | 2011
- 121
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Dynamic Simulation of the Dissolution of Pharmaceutical Tablet Integrated with Continuous Manufacturing ProcessBoukouvala, F. / Mioduszewski, L. / Ramachandran, R. / Ierapetritou, M.G. et al. | 2011
- 122
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Innovative Techniques for Planning Experiments Across Multiple Unit OperationsCanter, K. / Perry, L. et al. | 2011
- 123
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Real-Time Process Management and Knowledge Management for Continuous Pharmaceutical ManufacturingJoglekar, G. / Giridhar, A. / Reklaitis, G.V. / Venkatasubramanian, V. et al. | 2011
- 124
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Collagen Binding Domain Fusion Proteins for Therapeutics: Expression and IsolationFruchtl, M. / Moreland, H. / Beitle, R.R. / Sakon, J. et al. | 2011
- 125
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Identification of Macromolecular Designs for Inhibiting the Atherogenic Effect of Endothelial Scavenger Receptor, LOX-1Kamisoglu, K. / Poree, D. / Sparks, S.M. / Uhrich, K.E. / Welsh, W. / Moghe, P.V. et al. | 2011
- 126
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The Missing Links: Elucidating Mechanisms of Heterologous GPCR Expression and Trafficking In S. CerevisiaeYoung, C.L. / Britton, Z.T. / McCusker, E.C. / Caplan, J. / Czymmek, K.J. / Robinson, A.S. et al. | 2011
- 127
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Computational and Experimental Study of Palmitate Binding to the IRE1 ProteinCho, H.J. / Fang, L. / Palasuberniam, P. / Bush, C. / Feig, M. / Chan, C. et al. | 2011
- 128
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A Library of Inducible Synthetic Devices for Phenotype Regulation In ProkaryotesVolzing, K.G. / Biliouris, K. / Kaznessis, Y. et al. | 2011
- 129
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Designing Highly Active siRNAs From Asymmetry-Based Selection Algorithm PredictionsMalefyt, A.P. / Wu, M. / Chan, C. / Walton, S.P. et al. | 2011
- 130
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Streamlined Protocol for mRNA DisplayBarendt, P.A. / McQuade, C.N. / Sarkar, C.A. et al. | 2011
- 131
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Micropatterned Growth Factor-Containing Surfaces to Study Hepatic Response to InjuryPatel, D. / Jones, C. / Revzin, A. et al. | 2011
- 132
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Microfluidic Assay for Neutrophil Chemotaxis towards Chemoattractant GradientsJones, C.N. / Irimia, D. et al. | 2011
- 133
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Neutrophil Migratory Response In Competing Endogenous Chemotactic GradientsKapoor, A. / Kimura, Y. / Byrne, M. / He, Y. / Wang, F. / Kenis, P.J.A. / Rao, C.V. et al. | 2011
- 134
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A Combined Experimental and Theoretical Approach to Model Cell-Cell Interactions In Cancer Cell MigrationSarkar, S. / Bustard, B. / Welter, J.F. / Baskaran, H. et al. | 2011
- 135
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Comparing Monocyte Adhesion and Transendothelial Migration Between a 3D Vascular Tissue Model and a 2D Cell Culture System Under Normal Conditions and Activated with TNF-&alphaGhousifam, N. / Leemasawatdigul, K. / Fahlenkamp, H.G. et al. | 2011
- 137
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Optimization of Mesenchymal Stem Cell Migration In the Wound BedRodriguez, K. / Ghosh, D. / McAndrews, K. / McGrail, D. / Dawson, M. et al. | 2011
- 138
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Metastatic Cancer Cells Optimize Space-SearchingHuda, S. / Soh, S. / Tretiakov, K. / Pilans, D. / Kandere-Grzybowska, K. / Grzybowski, B. et al. | 2011
- 139
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Focal Adhesion Maturation and Dynamics Regulate Cell-to-Cell Variability In EGF-Stimulated MigrationSchneider, I. / Hou, Y. et al. | 2011
- 141
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Mucin-16 and Podocalyxin Are Functional Selectin Ligands Expressed by Pancreatic Cancer CellsChen, S.-H. / Dallas, M. / Thomas, S.N. / Konstantopoulos, K. et al. | 2011
- 142
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The Unexpected Nucleation/Polymorphic Transformation-Promoting Effect of Glycine on Crystallisation of L-Glutamic AcidRusin, M. / Ewan, B.C.R. / Ristic, R.I. et al. | 2011
- 143
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Implementation of a High-Resolution Population Balance Solver to Model Pharmaceutical CrystallizationsTabora, J.E. / Murugesan, S. / Vernille, J. / Braatz, R. / Fujiwara, M. / Rasche, M.L. et al. | 2011
- 144
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Optimal Control of Antisolvent and Cooling CrystallizationZhou, L. / Ma, K.-N. / Feng, H. / Braatz, R.D. et al. | 2011
- 146
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Super-Saturation Control In API Crystallization for Optimal Impurity Rejection and Particle Size DistributionCao, L. / Li, D. / Yang, Y. et al. | 2011
- 148
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Design of Nanostructured `Catalyst' for Nucleation of Molecular CrystalsDiao, Y. / Helgeson, M.E. / Doyle, P.S. / Myerson, A.S. / Hatton, T.A. / Trout, B.L. et al. | 2011
- 149
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Turbidity and Endoscopy Assisted Monitoring of Solvent Mediated Polymorphic Transformation ProcessesSimon, L.L. / Hungerbuehler, K. et al. | 2011
- 151
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Transcriptional Regulatory Network In Pluripotent Stem CellsSharma, S. / Yongky, A. / Verfaillie, C. / Hu, W.-S. et al. | 2011
- 152
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A Systems Approach to Identify Effects of Chronic Alcohol Intake On the Dynamic Gene Regulatory Response Patterns During Liver RegenerationVadigepalli, R. / Patra, B. / Kuttippurathu, L. / Juskeviciute, E. / Hoek, J. et al. | 2011
- 154
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Targeted Metabolomics of Cofactors In Liver Drug MetabolismYi, M. / Stachenfeld, K.L. / Sridharan, G.V. / Carson, K.A. / Lee, K. et al. | 2011
- 156
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Metabolic Flux Analysis Using 13C-Tracers and Tandem Mass SpectrometryAntoniewicz, M.R. / Choi, J. / Grossbach, M. et al. | 2011
- 157
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Quantitative Assessment of Cell Signaling Pathways Affecting Stem Cell Differentiation Using Lentiviral ArraysAlimperti, S. / Tian, J. / Lei, P. / Andreadis, S.T. et al. | 2011
- 159
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A Novel Experimental Approach to Investigate Cytokine Signaling Networks of Human T CellsHan, Q. / Bagheri, N. / Lauffenburger, D. / Love, J.C. et al. | 2011
- 160
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Pairwise Agonist Screening and Microfluidics Reveal Platelet Function PhenotypeColace, T. / Chatterjee, M. / Diamond, S.L. et al. | 2011
- 163
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Determination of Drop Size Distribution In a Centrifugal ContactorWyatt, N.B. / O Hern, T.J. / Shelden, B. et al. | 2011
- 164
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Effect of Impeller Submergence On Flow Characteristics and Minimum Agitation Speed for Solids Suspension In Partially Filled Stirred Vessels for Different Impeller off-Bottom Clearances and Impellers SizesMotamedvaziri, S. / Armenante, P. et al. | 2011
- 166
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Aggregation In Homogeneous, Isotropic TurbulenceDerksen, J. et al. | 2011
- 167
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Towards the Modelling of the Stabilization Process In Pickering EmulsionsFradette, L. / Tsabet, E. et al. | 2011
- 168
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Effect of Oxygen Bubble Distributions On Rare Earth Precipitates In Molten SaltsBezzant, R.W. / Phongikaroon, S. / Simpson, M.F. et al. | 2011
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Power Dissipation and Impeller Power Number In USP Dissolution Testing Apparatus 2Wang, Y. / Armenante, P.M. et al. | 2011
- 172
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A Combined Experimental and Model-Based Approach to Prediction of Particle Size Attrition In Agitated DryersMarchut, A.J. / Czyzewski, A.M. / Ho, R. / Orihuela, C. / Sheikh, A. / Nordstrom, F.L. / Borchardt, T.B. / Bordawekar, S.V. et al. | 2011
- 174
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Investigation of Acoustic Dryer for API ProcessingLamberto, D. / Lucon, P. / Nyquist, D.R. / Yarrington, J.E. et al. | 2011
- 176
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Near-Infrared Spectroscopy for On-Line Drying End-Point Determination In a Small-Scale Fluidized BedHeigl, N. / Khinast, J.G. / Glasser, B. / Muzzio, F.J. et al. | 2011
- 178
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Developing a Robust Isolation and Drying Protocol for An API with Unique Physical PropertiesRogers, A. / Murugesan, S. / Braem, A. / Deshpande, P. / Bartels, W. / Tabora, J. et al. | 2011
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Developing Dynamic Models of Pharmaceutical Drying Operations Using On-Line Mass SpectroscopyGopi, A. / Saranteas, K. / Henson, M.A. et al. | 2011
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Development of Laboratory Methods (``Predictive Tools'') to Preserve Particle Properties of APIs Upon Scale-up to Agitated Filter DriersMaloney, M.T. / Ende, D.J.A. / Brenek, S.J. / Maranzano, B. et al. | 2011
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Rapid Characterization and Engineering of Natural Product Biosynthetic Pathways Via DNA AssemblerShao, Z. / Luo, Y. / Zhao, H. et al. | 2011
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Engineering the Microalgae Strain Chlamydomonas Reinhardtii for Xylose UtilizationPourmir, A. / Johannes, T. et al. | 2011
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Kinetic Modeling of Isobutanol Fermentation by Recombinant Escherichia ColiXiao, Y. / Feng, X. / Yu, H. / Varman, A. / Tang, Y. et al. | 2011
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Uncovering Cryptic Biosynthetic Pathways Using Synthetic BiologyLuo, Y. / Shao, Z. / Zhao, H. et al. | 2011
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Substrate Specificity Change of a DehydrogenaseAbrahamson, M.J. / Bommarius, A.S. et al. | 2011
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Asymmetric Reduction of Alpha-Hydroxy Aromatic Ketones to Chiral Aryl Vicinal Diols Using Carrot Enzymatic SystemLiu, X. / Wang, Y. / Xu, J. et al. | 2011
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Phylogenetic and Experimental Characterization of An Acyl-ACP Thioesterase Family Reveals Significant Diversity In Enzymatic Specificity and ActivityCantu, D.C. / Jing, F. / Tvaruzkova, J. / Chipman, J.P. / Nikolau, B.J. / Yandeau-Nelson, M.D. / Reilly, P.J. et al. | 2011
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The Genome Sequence of the Chinese Hamster:Ushering In An Era of CHO Genome EngineeringJacob, N.M. / Vishwanathan, N. / Yusufi, F. / Chin, J.-X. / Lee, T.S. / Johnson, K.C. / Le, H. / Ramaraj, T. / Woodward, J. / Retzel, E.F. et al. | 2011
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Metabolic Flux Analysis of CHO Cells In Semi Fed-Batch CultureAntoniewicz, M.R. / Ahn, W.S. et al. | 2011
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The Metabolic Effects of An Anti-Apoptotic Protein Bcl-2 Delta Overexpressing CHO Cell LineTempleton, N. / Young, J. et al. | 2011
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Proteomic and Metabolic Flux Analysis of Recombinant CHO Cell CulturesMorgan, J.A. / Sengupta, N. / Zhang, M. et al. | 2011
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Bistability In Glycolysis Pathway As a Physiological Switch In Energy MetabolismMulukutla, B.C. / Yongky, A. / Daoutidis, P. / Hu, W.-S. et al. | 2011
- 200
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Dynamic Model for CHO Cell and Process EngineeringNolan, R.P. / Lee, K. et al. | 2011
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Towards the Implementation of QbD to the Production of Therapeutic Monoclonal Antibodies with Desired Glycosylation PatternsDel Val, I.J. / Kontoravdi, C. et al. | 2011
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Transport Modulation of Nanocarriers Across the Pulmonary Epithelium: Potential Strategy for the Local and Systemic Delivery of Drugs to and Through the LungsBharatwaj, B. / Conti, D.S. / Da Rocha, S.R.P. et al. | 2011
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High Throughput Evaluation of the In Vivo Biodistribution and Dispersion of Polyanhydride Nanoparticle AdjuvantsPetersen, L. / Huntimer, L. / Walz, K. / Ramer-Tait, A. / Wannemuehler, M.J. / Narasimhan, B. et al. | 2011
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Polyelectrolyte-Gold Nanorod Assemblies for Transgene DeliveryRamos, J. / Huang, H.-C. / Rege, K. et al. | 2011
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Nanoparticle/Heat-Responsive-Polymer Complex for Hyperthermia and Sustained Drug ReleaseWang, S. / Liu, M.C. / Kang, K.A. et al. | 2011
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Elastic Mapping of Epithelial Cells Treated with NanomaterialsDong, C. / Sargeni, L.Q. / Lowry, D.H. / Dinu, C.Z. et al. | 2011
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Enhanced Biodesulfurization by Magnetic Immobilized Rhodococcus Erythropolis LSSE8-1-Vgb Assembled with Nano-Al2O3Xing, J. / Zhang, T. / Wang, Z. / Li, W. et al. | 2011
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A Multiplexed Microfluidic Platform Utilizing Normally Closed Valves for Investigation of Microbial Gene ExpressionMohan, R. / Mukherjee, A. / Schroeder, C.M. / Kenis, P.J.A. et al. | 2011
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Influence of Nuclear Stiffness On Cell MigrationHarada, T. / Discher, D.E. et al. | 2011
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JNK Regulates Cell-Substrate and Cell-Cell Adhesion On Substrates of Varying ComplianceYou, H. / Ranganathan, A. / Andreadis, S.T. et al. | 2011
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F-Actin and Myosin IIa-Dependent Microtubule Targeting of Focal AdhesionsHuda, S. / Soh, S. / Byrska-Bishop, M. / Pilans, D. / Kim, J. / Kandere-Grzybowska, K. / Grzybowski, B. et al. | 2011
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Control On Glioblastoma Multiforme Dynamics Using Aligned Fiber NetworksSheets, K. / Nain, A.S. et al. | 2011
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Platelet Adhesion to Fibrinogen Patterned SubstratesFontenot, J. / Van De Walle, A.B. / Spain, T. / Schmidtke, D.W. et al. | 2011
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Engineering Bioadhesive Polyvinyl Alcohol Hydrogels for Aneurysm OcclusionRafat, M. / Rotenstein, L. / You, J.-O. / Auguste, D. et al. | 2011
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Influence of CD151 Expression and Endothelial Cell Phenotype On Selectivity of Cancer Cell Adhesion to Endothelial MonolayersFischer, J. / Shearer, A. / Deng, X. / Yang, X. / Eitel, R. / Anderson, K.W. et al. | 2011
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Engineering the Lymph Node Microenvironment with Controlled Release Polymer Particles for Enhanced VaccinationJewell, C.M. / Lopez, S.C.B. / Irvine, D.J. et al. | 2011
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Design and Characterization of Self-Assembling, Peptide-Based Biomaterials As ImmunotherapeuticsTrent, A. / Black, M.J. / Olive, C. / Tirrell, M. et al. | 2011
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siRNA Based Gene Therapy In Alzheimer's DiseaseChaudhary, A. / Garg, S. et al. | 2011
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Identifying Novel Bacterial Proteases Involved In Enhanced Virulence During Chronic InfectionMacdonald, L. / Nice, J. / O Keefe, S. / Berger, B.W. et al. | 2011
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Interplay of Flow and Oncotically Active Solute Transport Across the Arterial Endothelium: Hydraulic Conductivity Masking and Relevance to AtherogenesisJoshi, S.D. / Jan, K.-M. / Rumschitzki, D.S. et al. | 2011
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Molecularly Imprinted Polymeric Nanoparticles for Treating Viral Infections - A Synthetic Antibody ApproachTong, Y.W. / Sankarakumar, N. et al. | 2011
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Breast Cancer CSC Display Novel In Vivo Imaging Features, Reminiscent of Development, During Early Tumor ProgressionParashurama, N. / Lobo, N. / Clarke, M. / Gambhir, S.S. et al. | 2011
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What a Difference a Letter Makes: Aggregation of PolyA and PolyQBernacki, J.P. / Walters, R.H. / Murphy, R.M. et al. | 2011
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Synthetic YE8 Peptide Triggers Secondary Heterogeneous Nucleation of InsulinSorci, M. / Takor, G. / Higashiya, S. / Kurouski, D. / Gehan, T. / Zhang, S. / Lednev, I.K. / Welch, J.T. / Belfort, G. et al. | 2011
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Engineering of Non-Aggregating Alpha Synuclein VariantsHernandez, M. / Golbert, S. / Zhang, L.G. / Kim, J.R. et al. | 2011
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Curcumin Attenuates Amyloid Beta Peptide Toxicity by Forming off-Pathway IntermediatesThapa, A. / Chi, E.Y. et al. | 2011
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Structure-Function Analysis of the Novel Small Molecule Modulators of Amyloid-Beta Aggregation and CytotoxicityWong, H.-C. / Fernandez, E.E. / Kwon, I. et al. | 2011
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Mechanistic Inhibition of Alzheimer's-Associated A beta Aggregation by Gold NanoparticlesWilson, K.A. / Lim, M. / Jackson, K. / Mahtab, R. / Moss, M.A. et al. | 2011
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Conformational Differences Between Toxic and Non-Toxic Oligomers of AmyloidLadiwala, A.R.A. / Tessier, P.M. et al. | 2011
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QbD Principles for Packaging Design and Stability: A Regulatory PerspectiveChatterjee, S. et al. | 2011
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Stability In a QbD FrameworkKourti, T. et al. | 2011
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Science-Based Stability and Packaging Development Under the Umbrella of QbDChern, R. et al. | 2011
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Using QbD to Asses the Factors That Affect Stability and PackagingKrogmeier, S. / Bittorf, K.J. et al. | 2011
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Designing Pharmaceutical Packaging Using a Product-Packaging Stability ModelingYoon, S.-Y. et al. | 2011
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Implementation of QbD Paradigm In Sterile Dosage Form Packaging - Some Practical ConsiderationsJoshi, H.N. et al. | 2011
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Advances In Microalgal BiotechnologyChen, F. et al. | 2011
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Biobutanol R&D In ChinaLi, Y. / Zhang, Y. et al. | 2011
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Organic Acid In China: Progress and ProspectHuang, H. et al. | 2011
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Systematic Analysis and Decoupling of Yeast Tolerance to Combined Inhibitors In Liginocellulose HydrolytesYuan, Y.-J. / Ding, M.-Z. et al. | 2011
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How Polymer Enhances the Stability and Functionality of the Conjugated ProteinYang, C. / Zhu, B. / Lu, D. / Liu, Z. et al. | 2011
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Prodrugs AS Multifunctional Drug NanocarriersShen, Y. et al. | 2011
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Genome-Scale Metabolic Network Modeling Results In Minimal Interventions That Cooperatively Force Carbon Flux towards Malonyl-CoAXu, P. / Ranganathan, S. / Maranas, C.D. / Koffas, M.A.G. et al. | 2011
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Validation of Metabolic Network Model for E. Coli and Assumptions of 13C-Metabolic Flux Analysis and Using [U-13C]Glucose TracerAntoniewicz, M.R. / Leighty, R. et al. | 2011
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Metabolic Flux Analysis of the Central Metabolism of Laboratory and Industrial Saccharomyces Cerevisiae Strains Using 13C-Labeling ExperimentsKim, B. / Zhao, H. et al. | 2011
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Metabolic Flux Analysis Using Designed Isotope Labeling Experiments Reveals Effects of Light On Metabolic Fluxes In Heterotrophic Plant Suspension CellsNargund, S. / Joffe, M.E. / Tugarinov, V. / Sriram, G. et al. | 2011
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Metabolic Response of Perfused Livers to Various Oxygenation ConditionsOrman, M.A. / Mattick, J. / Ierapetritou, M.G. / Androulakis, I.P. / Berthiaume, F. et al. | 2011
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Probing Cancer Metabolism Using Isotope TracersMetallo, C.M. / Gameiro, P. / Stephanopoulos, G. et al. | 2011
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Isotopically Nonstationary Proteinogenic MFA As a Tool for Analysis of Tumor Cell MetabolismMurphy, T.A. / Young, J. et al. | 2011
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Application of Design Space Mapping Accounting for Model Uncertainty and Common Cause Variability In Drug Substance DevelopmentVaidyaraman, S. / Figueroa, I. / Wong, S.W. / Viswanath, S. et al. | 2011
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Design Space Development for the Final Recrystallization Process for Axitinib, a Complex Solvating APIGuinness, S.M. / Chekal, B.P. / Steeno, G.S. et al. | 2011
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Impurity Fate Mapping In the Development of PazopanibMcGuire, M.A. et al. | 2011
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A Model-Centric Solution to Link Content Uniformity Targets with API Particle Size Specifications and Process for a QbD ExcerciseGarcia-Munoz, S. / Yu, W. / Pinto, M.A. / Bermingham, S.K. et al. | 2011
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Process QbD Case Study: An Integrated PAT Approach for a Dynamic Pharmaceutical Co-Precipitation Process Characterization and Process Design Space DevelopmentWu, H. / White, M. / Khan, M.A. et al. | 2011
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A QbD Approach to Improve Tablet Coating UniformityDubey, A. / Boukouvala, F. / Keyvan, G. / Hsia, R. / Saranteas, K. / Brone, D. / Misra, T. / Ierapetritou, M. / Muzzio, F.J. et al. | 2011
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Evaporation-Driven Fluid Flow Enhances Sensitivity of An In Vitro Influenza Virus Drug-Susceptibility AssayLindsay, S.M. / Yin, J. et al. | 2011
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Single-Cell Kinetics of Infection by An RNA Virus: a Step Toward Drug-Targeting Strategies That Resist EscapeTimm, A.C. / Yin, J. et al. | 2011
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Engineering Hetero-Bivalent Peptidic Ligands to Inhibit Mast Cell Degranulation In AllergiesHandlogten, M.W. / Kiziltepe, T. / Bilgicer, B. et al. | 2011
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Model-Based Clustering Applied to Combinatorial LibrariesWhite, A.D. / Jiang, S. et al. | 2011
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Acetylcholinesterase Inhibitors Can Interfere In Amyloid- beta Self-Assembly: Potential As Multi-Target Drugs for Alzheimer's DiseaseTseng, J.-H. / Suo, C. / Davda, D. / Gao, J. / Terry, A. / Chapman, J. / Moss, M.A. et al. | 2011
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Identification of Mitochondria Damaging Agents Using Parallel ScreeningTaylor, D.J. / Jayaraman, A. / Rege, K. et al. | 2011
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Targeted Nitric Oxide Donor Enhances Efficacy of Chemotherapeutics Used to Treat Glioblastoma MultiformeSafdar, S. / Taite, L.J. et al. | 2011
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Living Polymerization/Reaction Control: Innovative Strategies for Enhancing Drug Delivery From Imprinted Thin FilmsSalian, V.D. / Byrne, M.E. et al. | 2011
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Stripfilms As Oral Dosage Platform for the Delivery of Nano-Particles of Active Pharmaceutical Ingredients (APIs)Dave, R.N. / Sievens-Figueroa, L. / Bilgili, E. et al. | 2011
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Particle Scale Study of the Dispersion of Dry Powder In Pharmaceutical Aerosol InhalersTong, Z.B. / Yang, R.Y. / Yu, A.B. / Adi, S. / Chan, H.-K. et al. | 2011
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A Microfluidic Platform for Aerosol and Nanoparticle Drug and Gene DeliveryQi, A. / Rajapaksa, A. / Chan, P. / Friend, J. / Yeo, L.Y. et al. | 2011
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Development of Anti-Tubercular Nanoscale Drug Cocktails for Targeted TherapyD Addio, S.M. / Reddy, V. / Kwok, P. / Einck, L. / Chan, H.-K. / Prud Homme, R. et al. | 2011
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Engineering Multifunctional Nanoparticles for Overcoming Drug Resistance In Multiple MyelomaKiziltepe, T. / Ashley, J.D. / Stefanick, J. / Bilgicer, B. et al. | 2011
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Melt Mixing Active Pharmaceutical Ingredient and Polymer to Achieve Different Release ProfilesAdegoke, A. / Sarode, A. / Wang, P. et al. | 2011
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A Novel SHF Process for Conversion of AFEX-CS to Ethanol Featuring High Ethanol Productivity, Enzyme Recycling, and Yeast Cells ReuseJin, M.J. / Gunawan, C. / Uppugundla, N. / Chundawat, S. / Dale, B. / Balan, V. et al. | 2011
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Concentration of a Solids-Free Lignocellulose Hydrolysate for Very High Gravity Fermentation: Inhibition EffectsSchneiderman, S.J. / Menkhaus, T.J. / Gilcrease, P.C. et al. | 2011
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Separate Processing of Hemicellulose and Cellulose to Optimize Ethanol Production From Corn StoverChapeaux, A. / Dowe, N. / Schell, D.J. et al. | 2011
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Ethanol and Furfural Production From Corn Stover Using Hybrid Fractionation Process with Zinc Chloride and Simultaneous Saccharification and Fermentation (SSF)Yoo, C.G. / Kim, T.H. / Kuo, M. et al. | 2011
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Fischer Tropsch Synthesis Via Biomass Derived Synthesis GasGardezi, S.A. / Joseph, B. / Wolan, J.T. et al. | 2011
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Integrations of Biosurfactant Production Into Advanced BiorefineriesColonna, W. / Marti, M.E. / Pynn, M. / Reznik, G. / Jarrell, K. / Lamsal, B. / Glatz, C.E. et al. | 2011
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Structure and Application of Nucleic Acid-Surfactant Films for Transfection In Human CellsPerry, S.L. / Gajria, S. / Neumann, T. / Ni, J. / Weinstein, J. / Schaffer, D.V. / Tirrell, M.V. et al. | 2011
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Analysis of siRNA Transport and Delivery within 3-Dimensional Collagen MatricesMalefyt, A.P. / Hinds, E. / Jayaraman, A. / Kuo, C. / Lee, K. / Chan, C. / Walton, S.P. et al. | 2011
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Design, Synthesis and Evaluation of Poly (amino ethers) for Efficient Transgene DeliveryPotta, T. / Vu, L. / Rege, K. et al. | 2011
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Microarray Analysis of Gene Expression Profiles Characteristic of Successfully Transfected CellsMartin, T.M. / Plautz, S.A. / Riethoven, J.-J.M. / Pannier, A.K. et al. | 2011
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Dynamics of DNA Release From Polyplexes Induced by Inter-Polyelectrolyte ExchangeZou, Y. / Mao, G. et al. | 2011
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Interplay of Matrix Rigidity and Cell Type for Non-Viral Gene DeliveryChu, C. / Kong, H. et al. | 2011
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Gene Activated Matrix Transfection of Human Mesenchymal Stem Cells by Chitosan-DNA Nanoparticles In Chitosan-Based ScaffoldsHunter, K.T. / Ma, T. et al. | 2011
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FDA Perspective On QbD for Analytical MethodsMorefield, E. et al. | 2011
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Quality by Design for Analytical Methods In Early DevelopmentPellett, J. et al. | 2011
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Examples of Applying Quality by Design Principles to Analytical MethodsBarnett, K. / Graul, T. / Hanna-Brown, M. et al. | 2011
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Quality by Design for Particle Size AnalysisSun, Z. et al. | 2011
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High-Throughput Evolutionary Substrate Screening for Embryonic Stem Cell Attachment and Long-Term MaintenanceZonca, M.R. / Yune, P.S. / Belfort, G. / Xie, Y. et al. | 2011
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Bioactive Peptides for Mesenchymal Stem Cell Differentiation In Cartilage Tissue EngineeringRenner, J.N. / Kim, Y. / Liu, J.C. et al. | 2011
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An Injectable, Self-Healing Protein Hydrogel for Stem Cell DeliveryLampe, K.J. / Aguado, B. / Parisi-Amon, A. / Mulyasasmita, W. / Su, J. / Heilshorn, S.C. et al. | 2011
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Decellularization of Tissue Engineered Leaflets with Adult Stem Cell RecellularizationSyedain, Z. / Bradee, A. / Tranquillo, R.T. et al. | 2011
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Guided Cardiogenic Differentiation of Human Pluripotent Stem Cells In Static and Stirred-Suspension CulturesJing, D. / Parikh, A. / Tzanakakis, E.S. et al. | 2011
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Controlling the Electrophysiological Maturation of Stem Cell-Derived Cardiomyocytes Via Nitric Oxide SupplementationHodge, A.J. / Morris, J.H. / Lipke, E.A. et al. | 2011
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Functional Smooth Muscle Cells Derived From Induced Pluripotent Stem Cells for Cardiovascular Tissue Engineering ApplicationsBajpai, V.K. / Andreadis, S.T. et al. | 2011
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Metabolic Flux Analysis of Escherichia Coli MG1655 Under Octanoic Acid StressFu, Y. / Yoon, J.M. / Royce, L.A. / Rodriguez-Moya, M. / Gonzalez, R. / Jarboe, L. / Shanks, J.V. et al. | 2011
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Metabolic Engineering of Rhizopus Oryzae for Enhanced Production of Fumaric Acid From SugarsZhang, B. / Yang, S.-T. et al. | 2011
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Styrene Biosynthesis from Glucose by Engineered E. ColiMcKenna, R. / Nielsen, D.R. et al. | 2011
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Enhanced Xylitol Production Through Simultaneous Co-Consumption of Cellobiose and Xylose by An Engineereed Saccharomyces Cerevisiae StrainOh, E.J. / Ha, S.-J. / Kim, S.R. / Galazka, J.M. / Cate, J.H.D. / Jin, Y.-S. et al. | 2011
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alpha -Olefin Biosynthesis In the Cyanobacterium Synechococcus Sp. PCC7002Mendez-Perez, D. / Begemann, M.B. / Pfleger, B.F. et al. | 2011
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Building a Better Biofuel Production Platform: Engineering Metabolic Control Techniques to Control the Photosynthetic Cyanobacterium Synechocystis Sp. PCC 6803Albers, S. / Peebles, C.A.M. et al. | 2011
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Proteomic, Physiological, and In Silico Testing of Economic Tradeoffs In Metabolic NetworksCarlson, R.P. / Taffs, R. / Folsom, J.P. et al. | 2011
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Pattern Formation In the Acto-Myosin Cortex: An Active Reaction-Diffusion-Advection ProcessBois, J.S. / Julicher, F. / Grill, S.W. et al. | 2011
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SHREDing a Biochemical Network Into Hierarchical ModulesSridharan, G.V. / Hassoun, S. / Lee, K. et al. | 2011
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Shewanella Oneidensis MR-1 Population-Level Chemotaxis In a Diffusion Gradient ChamberLi, R. / Auchtung, J.M. / Tiedje, J.M. / Worden, R.M. et al. | 2011
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Higher Order Gene Deletion Mutants Give Insights On Latent Pathway ActivationGawand, P. / Mahadevan, R. et al. | 2011
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Derivation of a Kinematic Model Coupling Stress Fiber Dynamics with JNK Activation In Response to Matrix StretchingKaunas, R. / Huang, Z. / Hahn, J. et al. | 2011
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A Systems Biology Approach to Identify Immune Targets That Control Tuberculosis Granuloma FunctionFallahi-Sichani, M. / Kirschner, D.E. / Linderman, J.J. et al. | 2011
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Dissecting Gene Regulation Through DNA Loop Formation Using Statistical Mechanical Models and ExperimentsBoedicker, J. / Garcia, H. / Phillips, R. et al. | 2011
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Regulation of Epidermal Growth Factor Receptor Phosphorylation and Endocytosis Dynamics by Protein Tyrosine PhosphatasesMonast, C.S. / Lazzara, M.J. et al. | 2011
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Evaluating Metabolic Network Elements Via a Forced Coupling AlgorithmTervo, C.J. / Reed, J.L. et al. | 2011
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Robust Selection of Gene ModificationsYousofshahi, M. / Orshansky, M. / Lee, K. / Hassoun, S. et al. | 2011
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Flux Balance Analysis of Plant Suspension Cell CultureMisra, A. / Simons, M. / Conway, M. / Coleman, G.D. / Sriram, G. et al. | 2011
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Immersed Boundary Model of Biofilm Deformation In Response to Fluid FlowHeys, J.J. / Vo, G.D. et al. | 2011
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Modeling Population Dynamics of Cancer Stem Cells with Epithelial-Mesenchymal TransitionLee, H. / Yoon, S. et al. | 2011
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Intra-Thrombus Transport and Local Shear Stress Distributions Modeling Based On In-Vivo Imaging with Single Platelet ResolutionVoronov, R.S. / Stalker, T.J. / Brass, L.F. / Diamond, S.L. et al. | 2011
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Kinetics and Modeling of Disproportionation Reactions Catalyzed by Clostridium Acetobutylicum and Ruminococcus Flavefaciens EndoglucanasesWarner, C.D. / Ford, C. / Reilly, P.J. et al. | 2011
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Inflamed Leukocyte-Mimetic Nanoparticles for Molecular Imaging of Inflammation: Application to Detection of Tumor and Acute InflammationChen, X. / Wong, R. / Khalidov, I. / Wang, Y.A. / Leelawattanachai, J. / Wang, Y. / Jin, M. et al. | 2011
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Stable High Affinity Streptavidin Protomers for Cell Biology ApplicationLim, K.H. / Hsu, C.K. / Huang, H. / Pralle, A. / Park, S. et al. | 2011
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Engineering High-Affinity, Aggregation-Resistant Domain AntibodiesPerchiacca, J.M. / Bhattacharya, M. / Tessier, P.M. et al. | 2011
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Isolation and Characterization of Novel Antibodies That Target the Blood-Brain BarrierStutz, C.C. / Jones, A.R. / Tan, S.-Z. / Shusta, E. et al. | 2011
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Using An Orthogonal Ligand-Receptor Pair to Control Endogenous Gene Expression In Mammalian CellLiang, J. / McLachlan, M. / Zhao, H. et al. | 2011
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De Novo Protein Design of Agonists and Antagonists of the C3a Receptor: Theoretical Predictions and Experimental ValidationPeterson, M.B. / Fung, H. / Floudas, C.A. / Morikis, D. / Monk, P.N. / Woodruff, T.M. et al. | 2011
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Directed Evolution of Bright Mutants of a Flavin Dependent Anaerobic Fluorescent Protein From Pseudomonas PutidaMukherjee, A. / Schroeder, C.M. et al. | 2011
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Ampicillin Synthesis Using a Two-Enzyme Cascade System with Both &alpha-Amino Ester Hydrolase and Penicillin G AcylaseBlum, J. / Deaguero, A.L. / Perez, C.V. / Bommarius, A.S. et al. | 2011
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Continuous Processing As a Process Development Tool for Fast ReactionsHamedi, M. / Gnanadesikan, V. / Zarkadas, D. / Pridgen, C. / Wu, G. et al. | 2011
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Kilos and Beyond: Using Continuous Chemistry to Speed Early Candidate Delivery and the Hurdles Incumbent throughout the Development ProcessVan Alsten, J.G. / Li, B. / Lucas, J. / Place, D. et al. | 2011
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Synthesis of 7-Methoxy -4'-Substituted Flavones As Potential Pharmaceutically Active CompoundsAn, J. / Liu, X. / Wang, Y. et al. | 2011
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Progress In Quality by Design Implementation In Fda's Office of New Drug Quality AssessmentMoore, C. et al. | 2011
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QbD Approaches for Continuous ManufacturingMuzzio, F.J. et al. | 2011
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Experiences with Quality by Design Filings and Prior Approval InspectionsBalducci, C. et al. | 2011
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Quality by Design for Generic DrugsPeng, Y. et al. | 2011
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Quality by Design (QbD), Biopharmaceutical ManufactureBrorson, K. et al. | 2011
- 402
-
Optimal Strain Design of Saccharomyces Cerevisiae for Bioethanol ProductionQuarterman, J.C. / Jin, Y.-S. / Price, N.D. / Kim, P.-J. et al. | 2011
- 403
-
Towards Cellulosic Biodiesel: Engineering Xylose and Lipid Metabolism In YeastTai, M. / Stephanopoulos, G. et al. | 2011
- 404
-
Metabolic Engineering of Fatty Acid Pathways In Synechocystis PCC 6803 for Biofuel ProductionCheah, Y.E. / Peebles, C.A.M. et al. | 2011
- 405
-
Predicting Immediate Behaviors of Engineered Microbial Strains for Biofuel ProductionKim, J. / Maravelias, C.T. / Reed, J.L. et al. | 2011
- 408
-
Functional Genomics Study of Fatty Acid Overproduction In Escherichia ColiLennen, R.M. / Kruziki, M.A. / Kumar, K. / Zinkel, R.A. / Burnum, K.E. / Lipton, M.S. / Hoover, S.W. / Ranatunga, R. / Wittkopp, T.M. / Marner, W.D. et al. | 2011
- 409
-
Transcriptomic and Proteomic Profiling of Ethanol-Tolerant Clostridium ThermocellumSui, S. / Goh, L.T. / Griffin, T.J. / Hu, W.-S. et al. | 2011
- 410
-
Conversion of Proteins Into Biofuels by Engineering Nitrogen FluxHuo, Y. / Cho, K.M. / Liao, J.C. et al. | 2011
- 412
-
Development of a Continuous Filter-Drier for Lab to Kilo-Lab ScaleEnde, D.J.A. / Pfisterer, D. / Girard, K. / Blackwood, D. / Plocharczyk, E. et al. | 2011
- 413
-
Development of a Continuous Process for Tasisulam SodiumGroh, J.M. / White, T.D. / Berglund, K.D. / Johnson, M.D. et al. | 2011
- 414
-
API Attribute Control by Continuous Fast Crystallization/PrecipitationZarkadas, D. / Pridgen, C. / Hamedi, M. / Grigorov, P. / Whittington, M. et al. | 2011
- 416
-
Efficient and Cost Effective Dehydration of Pharmaceutical Streams by PervaporationZarkadas, D. / Feng, R. / Wu, M. / Grigorov, P. / Lekhal, A. / Molter, K. et al. | 2011
- 418
-
Failure Mode Analysis of Continuous Process with Process ModelsWong, S.W. / Kokitkar, P.B. / Berglund, K.D. / Johnson, M. et al. | 2011
- 419
-
Novel Concepts for Continuous Purification of APIs Using Electro- ChromatographyBraunbruck, M.-G. / Gruber-Woelfler, H. / Feenstra, P. / Laskowski, R. / Bart, H.-J. / Khinast, J.G. et al. | 2011
- 421
-
Taking PAT From the Laboratory to Commercial ManufacturingLapack, M.A. / Jeffery, S.B. / Doherty, S.J. / Martinelli, J.R. / Burcham, C.L. et al. | 2011
- 422
-
Combining Microwave Resonance Technology to Multivariate Data Analysis As a Novel PAT Tool to Improve Process Understanding In Fluid Bed GranulationLourenco, V. / Herdling, T. / Reich, G. / Menezes, J.C. / Lochmann, D. / Schewitz, J. et al. | 2011
- 423
-
PAT Application and Validation of Online Particle Sizing Measurement for Controlling a Critical Quality AttributeBittorf, K.J. et al. | 2011
- 424
-
Experimental and Theoretical Study of Lyophilization From a Packing of Vials: Using of Tunable Diode Laser Absorption Spectroscopy (TDLAS) for Process Monitoring and Model CalibrationRajniak, P. / Mifkovich, C. / Farber, L. et al. | 2011
- 426
-
Optical Coherence Tomography: A New PAT-Tool for Fast and Non-Destructive Analysis of Tablet Coating QualityKoller, D.M. / Schinwald, C. / Scheibelhofer, O. / Leitner, M. / Khinast, J.G. et al. | 2011
- 427
-
QbD-Driven PAT Applications for Precision Spray-Coating Development and ControlMiller, C. / Thompson, B.T. / Zhang-Plasket, F. / Schilling, P.T. / Higgins, J. / Thurau, G. / Ramasamy, M. / Ahuja, E. et al. | 2011
- 428
-
Process Analytical Technology for Recombinant Pandemic Flu Vaccines: Viral Ultrastructure, Aggregation, and BindingTsai, D.-H. / Lipin, D. / Guha, S. / Feldblyum, J. / Cole, K.D. / Brorson, K.A. / Zachariah, M. / Tarlov, M.J. / Middelberg, A.P.J. / Pease, L.F. et al. | 2011
- 444
-
Developing a Novel Preparation Method for Residual Biomass Polymer BlendsZhang, J. et al. | 2011
- 446
-
Polymerization of Lactide to Polylactic Acid and Co-Polymers of Polylactic Acid Using High Viscosity Kneader ReactorsSafrit, B.T. / Schlager, G.E. et al. | 2011
- 447
-
Biodegradable Poly(hydroxyalkanoate) FoamsTsui, A. / Liao, Q. / Frank, C.W. et al. | 2011
- 450
-
Modification of Biomass Rheology: The Influence of Physical ChemistrySamaniuk, J.R. / Scott, C.T. / Root, T.W. / Klingenberg, D.J. et al. | 2011
- 451
-
Torrefied Wood Pellets Production Using Natural Biomass CompoundsPenmetsa, V.K. / Steele, P. et al. | 2011
- 454
-
Mechanical Strain Decreases the Rate of Fibrin Gel Degradation by PlasminAdhikari, A.S. / Mekhdjian, A. / Dunn, A.R. et al. | 2011
- 455
-
Engineering Synthetic ECM Analogs Using Elastin Mimetic PeptidesPatel, D. / Menon, R. / Taite, L. et al. | 2011
- 457
-
Increased Schwann Cell Migration Speed and Directionality Occurs During Electrical Stimulation Through Polypyrrole SubstratesForciniti, L. / Ybarra, J. / Zaman, M.H. / Schmidt, C. et al. | 2011
- 458
-
Improving Cochlear Implant Performance by Directing Nerve Growth with Photopolymerized MicropatternsTuft, B. / Clarke, J. / White, S. / Hansen, M. / Guymon, C.A. et al. | 2011
- 459
-
Fibril Alignment Induces Alignment of Sprouts From Endothelial Cell Spheroids In Fibrin GelMorin, K.T. / Tranquillo, R.T. et al. | 2011
- 460
-
Dynamic Adhesion of Endothelial Progenitor Cells On Peptide-Coupled Hydrogels Under FlowSeeto, W.J. / Lipke, E.A. et al. | 2011
- 461
-
Cell Adhesion On Thermosensitive Bio-Inert Materials with a Tunable LCSTLing, K. / Wischerhoff, E. / Anderson, L.S. et al. | 2011
- 462
-
Elucidating Human Transferrin-Receptor Interactions Using Linear Epitope MappingKarande, P. / Chandra, D. et al. | 2011
- 463
-
Dendrimer-Based Nanotherapeutics for Targeted Post-Natal Therapy In Cerebral Palsy: Chemistry, Mechanism and In Vivo EfficacyKannan, R.M. / Navath, R. / Dai, H. / Balakrishnan, B. / Romero, R. / Kannan, S. et al. | 2011
- 465
-
Early T Cell Activation Events In the Context of Single Dose Vaccination with Polyanhydride NanoparticlesHuntimer, L. / Ross, K.A. / Ramer-Tait, A. / Narasimhan, B. / Wannemuehler, M.J. et al. | 2011
- 466
-
Delivery of a Phospholipid Agent From a Silicone Hydrogel Contact LensPitt, W.G. / Zhao, Y. / Perez, K.X. / Nelson, J.L. / Pruitt, J.D. et al. | 2011
- 468
-
Lytic Peptide-Polymer Conjugate with Enhanced Potency and Sensitivity to Tumor-Associated ProteaseChau, Y. / Zhong, J. et al. | 2011
- 470
-
Development of Aptamer-Amphiphiles for Targeted Delivery to Colon Cancer Cells Expressing FractalkineWaybrant, B.M. / Lamont, E.A. / Pearce, T.R. / Sreevatsan, S. / Kokkoli, E. et al. | 2011
- 471
-
Molecularly Imprinted Extended-Wear Contact Lenses with Controlled Delivery of High Molecular Weight Comfort MoleculesWhite, C.J. / McBride, M.K. / Byrne, M.E. et al. | 2011
- 472
-
Removal of Selenite with Microbial Fuel Cells Utilizing Shewanella Oneidensis MR-1Chellamuthu, P. / Ward, M. / Nealson, K. / Kronen, M. et al. | 2011
- 474
-
Reaction Mechanism of Catalytic Oxidative Depolymerization of Cellulosic BiomassLin, H. et al. | 2011
- 475
-
Infrared Spectroscopy and Thermo Gravimetric Analysis for Cellulose and Residue by Hydrothermal DecompositionGeng, L. / Zhu, Z. et al. | 2011
- 476
-
Landfill Gas Utilization In Gas Turbines: Experimental Results for Combustion of Landfill Impurities In Premixed FlamesJalali, A. / Motamedhashemi, M. / Egolfopoulos, F.N. / Tsotsis, T. et al. | 2011
- 477
-
New Modeling Framework of Enzymatic Hydrolysis of CelluloseZhang, Y. / Zhou, W. et al. | 2011
- 478
-
Theoretical Analysis of Biodiesel Production Under High Temperature and Pressure ConditionsOlmos, F. / Manousiouthakis, V. et al. | 2011
- 479
-
Multiparametric Characterization of Actively-Secreting B Cells Reveals Dissimilarities Between HIV-1 Specific Responses In Blood and GALTOgunniyi, A.O. / Kwon, D. / Varadarajan, N. / Walker, B.D. / Love, J.C. et al. | 2011
- 480
-
Quantitative Proteomic Discovery of the Epigenetic Mechanisms That Control Human Cytomegalovirus InfectionDimaggio, P.A. / O Connor, C.M. / Shenk, T. / Garcia, B.A. et al. | 2011
- 482
-
Parallel Analysis of Transcription FactorsBilgin, B. / Walton, S.P. et al. | 2011
- 483
-
Microfluidics-Based Quantitative Screening of C. Elegans with Adaptive AlgorithmLee, H. / Crane, M. / Lu, H. et al. | 2011
- 484
-
Temporal Gene Expression Profiling In Live Cell Array: Application In Understanding Mesenchymal Stem Cell Differentiation towards Myogenic LineageMoharil, J. / Lei, P. / Tian, J. / Andreadis, S. et al. | 2011
- 486
-
Use of 3D Free Form Fabrication for Design of Functional Human TissuesSingh, G. / Trasatti, J.P. / Lee, V. / Dai, G. / Karande, P. et al. | 2011
- 487
-
Modeling the Residence Time Distribution In a Batch Fermentor: Comparison of CFD Prediction with ExperimentDutta, A. / Fernandes, R.L. / Heins, A.-L. / Lantz, A.E. / Jensen, A.D. / Gernaey, K.V. / Nopens, I. et al. | 2011
- 489
-
Mixing It up: Probing Cell Culture Bioreactors Using CFD ModelingSorensen, E.T. / Jaluria, P. / Munholand, L. / Adams, D. et al. | 2011
- 490
-
Effect of Different Agitation Systems and Protocols On the Growth of Nicotiana Tabacum Cells: Comparison of Growth Kinetics In Erlenmeyer Flasks, Conventional Stirred Tanks, and Eccentrically Agitated Tank BioreactorsCastillo-Reyna, J. / Alvarez, M.M. et al. | 2011
- 498
-
Bioreactor Mass Transfer At Large ScaleBrown, S. et al. | 2011
- 499
-
Development of a Method to Measure Bioreactor Mass TransferFrank, G. et al. | 2011
- 500
-
Experimental Measurement and CFD Modelling of Bubble Size Distribution in An Aerated Stirred TankKalal, Z. / Jahoda, M. et al. | 2011
- 510
-
Improved Thermostability of AEH by Combining B-FIT Analysis and Structure-Guided Consensus MethodBlum, J. / Ricketts, M.D. / Bommarius, A.S. et al. | 2011
- 511
-
Using the Unconventional Nucleotide Binding-site for Affinity Purification of AntibodiesAlves, N.J. / Handlogten, M.W. / Ashley, J.D. / Kiziltepe, T. / Bilgicer, B. et al. | 2011
- 512
-
Construction of Intein-Mediated Bioactive Protein HydrogelChen, Z. / Ramirez, M. et al. | 2011
- 513
-
Engineering a Reversible and High-Affinity Scaffold for Protein PurificationLiu, F. / Chen, W. et al. | 2011
- 514
-
Azide-Bearing Amino Acid Incorporation Into Recombinant Proteins In E. ColiAbdeljabbar, D.M. / Link, A.J. et al. | 2011
- 515
-
Site-Specific Labeling of Transcription Factors Using Non-Canonical Amino Acids and Ring Strain-Promoted [2+3] Cycloaddition Via Copper-Free Click ChemistryKim, Y. / Kim, S. / Katzenellenbogen, J.A. / Schroeder, C.M. et al. | 2011
- 516
-
Engineering a Ligand-Free Molecular Switch In Bacterial Flagellar MotorLele, P. / Nathan, V. / Berg, H.C. et al. | 2011
- 517
-
Classical and Chemical Imaging Applied to Food ``Grains'' Processing and Control: A Critical ReviewBonifazi, G. et al. | 2011
- 518
-
A New Drug Screening Method for Chinese Herbal Medicines As Enhancers for Embryonic Stem Cell ProliferationLi, D. / Wang, J. / Yang, S.-T. et al. | 2011
- 519
-
Effects of High Pulsed Magnetic Field On Enzymes and Microorganisms In Strawberry JuiceXiao, K. / Luo, L.-P. / Jin, J.-T. / Zheng, B.-S. / Ren, Y. et al. | 2011
- 520
-
Compressed Gas Fractionation of High Value Lipids From PlantsTallon, S.J. et al. | 2011
- 521
-
Furan Formation During UV-Treatment of Fruit JuicesBule, M. / Desai, K. / Parisi, B. / Parulekar, S.J. / Slade, P. / Singhal, R. / Rodriguez, A. et al. | 2011
- 522
-
Supercritical Carbon Dioxide Inactivation of Listeria Monocytogenes Spiked On Dry Cured Ham Pig SkinFerrentino, G. / Balzan, S. / Spilimbergo, S. et al. | 2011
- 530
-
The Use of Real-Time PCR to Determine the Growth Kinetics of Fungal Biomass On Solid Food At Different Water ActivitiesArquiza, J.M.R.A. / Hunter, J.B. et al. | 2011
- 531
-
Designing Novel Cellulase Systems Through Agent Based Modeling and Global Sensitivity AnalysisApte, A. / Senger, R.S. / Fong, S.S. et al. | 2011
- 532
-
Improving Exogenous Sugar Utilization by Engineered TransportersYoung, E.M. / Alper, H. et al. | 2011
- 533
-
Metabolic Engineering of Saccharomyces Cerevisiae for Improved Xylose UtilizationZhou, H. / Cheng, J. / Stephanopoulos, G. et al. | 2011
- 535
-
Elementary Mode Analysis of Ralstonia Eutropha Metabolism for the Production of Useful MetabolitesLopez, G. / Srienc, F. et al. | 2011
- 536
-
Analysis of Growth of Thermus Thermophilus HB8 Using Mini-bioreactors and Defined Growth Medium Without Yeast ExtractAntoniewicz, M.R. / Lu, J. et al. | 2011
- 537
-
Comparative Genomic Analysis of a High n-Butanol Tolerant and Producing Mutant Strain of ClostridiumZhao, J. / Yang, S.-T. et al. | 2011
- 538
-
Probing Carbon Flow Patterns in a Photosynthetically Efficient Marine Diatom Toward Biofuel ProductionZheng, Y. / Sriram, G. et al. | 2011
- 539
-
Transferring Monitoring Models Between Different Scales Through Multivariate Statistical TechniquesTomba, E. / Facco, P. / Bezzo, F. / Garcia-Munoz, S. / Barolo, M. et al. | 2011
- 541
-
Implementation of Genetic Algorithms In the Generation of High-Order Statistical ModelsMack, B.C. / Domagalski, N. / Hallow, D. / Fenster, M. / Hobson, L. / Tabora, J. et al. | 2011
- 542
-
Understanding the Impact of the Properties of Raw Materials Onto Product Quality Using JR-PLSGarcia-Munoz, S. et al. | 2011
- 543
-
De-Risking Scale-up of a High Shear Wet Granulation Process Using Latent Variable Modeling and near Infrared SpectroscopyMuteki, K. / Yamamoto, K. / Reid, G.L. / Krishnan, M.K. et al. | 2011
- 544
-
Diverse Uses of Latent Variable Methods In Vaccines and Biologics ManufacturingMiller, C. / Obando, L. / Higgins, J. et al. | 2011
- 545
-
Insights Into Lactate Metabolism Through Multivariate Analysis of Cell Culture Bioprocess DataLe, H. / Kabbur, S. / Sun, Z. / Pollastrini, L. / Johnson, K. / Mills, K. / Karypis, G. / Hu, W.-S. et al. | 2011
- 546
-
Continuous Production of Stable Drug Nanoparticle Suspensions Via Wet Stirred Media MillingBilgili, E. / Afolabi, A. et al. | 2011
- 547
-
A Plant-Wide Dynamic Model of a Continuous Pharmaceutical ProcessBenyahia, B. / Lakerveld, R. / Barton, P.I. et al. | 2011
- 548
-
NIR Spectroscopy with Multivariate Statistical Process Control for Selected Pharmaceutical ProcessesHeigl, N. / Wahl, P. / Scheibelhofer, O. / Koller, D. / Schlingmann, M. / Reiter, F. / Straka, G. / Khinast, J.G. et al. | 2011
- 549
-
Optimizing Continuous Powder Mixing Processes Using Periodic Section ModelingGao, Y. / Muzzio, F.J. / Ierapetritou, M.G. et al. | 2011
- 552
-
Model-Based Control of An Integrated Continuous Pharmaceutical Manufacturing ProcessRamachandran, R. / Chaudhury, A. / Ierapetritou, M.G. et al. | 2011
- 553
-
The Effects of Hydrophobically Modified Chitosan On LiposomesZheng, R. / Zhan, J. / Dowling, M.B. / Raghavan, S.R. / St. Dennis, J. / Venkataraman, P. / He, J. / John, V.T. et al. | 2011
- 554
-
Combating Pseudomonas Aeruginosa Biofilm Infections Using Synergistic Drug TherapiesRoss, S. / Kock, A. / Sanchez, L. / Fiegel, J. et al. | 2011
- 556
-
Drug Delivery Using Stimuli-Responsive Polymer Gel SpheresNinawe, P. / Parulekar, S.J. et al. | 2011
- 557
-
Synthesis of Polyanhydride Particles As An Antibiotic Delivery Platform Against Intracellular PathogensPhanse, Y. / Brenza, T. / Carrillo-Conde, B. / Narasimhan, B. / Bellaire, B.H. et al. | 2011
- 558
-
Discovery of Tight Junction Disrupting Peptides for Drug Delivery to the BrainTrasatti, J.P. / Karande, P. et al. | 2011
- 559
-
Lung Targeting with Triggered Release Using Gel Microparticles with Encapsulated NanoparticlesPinkerton, N.M. / Shi, L. / Wan, J. / Benson, B. / Prud Homme, R.K. / Stone, H.A. / Sinko, P.J. et al. | 2011
- 561
-
Mechanistic Studies of Self Emulsifying Drug Delivery Systems for the Oral Delivery of Lipophilic DrugsBuyukozturk, F. / Benneyan, J. / Carrier, R.L. et al. | 2011
- 564
-
Formation of Itraconazole-Malic Acid Cocrystals In a CO2-Expanded LiquidOber, C.A. / Gupta, R.B. et al. | 2011
- 565
-
Preparation of Calcium Stearate Pellets by Extrusion/Spheronization: Effect of Drying TechniqueSchrank, S. / Hodzic, A. / Glasser, B. / Zimmer, A. / Khinast, J.G. / Roblegg, E. et al. | 2011
- 567
-
Particle Engineering Via Dry Coating: Development of a Novel Material Sparing Technology for Pharmaceutical PowdersDave, R.N. / Beach, L. / Scicolone, J.V. / Gurumurthy, L. et al. | 2011
- 568
-
Microstructural Characterization and Dissolution Behavior of Drug/Semicrystalline Polymer SystemsZhu, Q. / Taylor, L. / Harris, M.T. / Hsu, H.-Y. et al. | 2011
- 569
-
In Vivo Cellular Uptake of PEGylated NanoparticlesZhan, X. / Tran, K.K. / Shen, H. et al. | 2011
- 570
-
On Single Step Assembly of Uniform Core-Shell Microparticles with Tunable Controlled Release FunctionalitiesLiu, W. / Wu, W.D. / Selomulya, C. / Chen, X.D. et al. | 2011
- 572
-
Spray Drying of Uniform Silica Microencapsulates: Implications for Controlled ReleaseWu, W.D. / Liu, W. / Selomulya, C. / Chen, X.D. et al. | 2011
- 574
-
Integrated Biogeochemical Modeling for Sustained Uranium RemovalZhao, J. / Mahadevan, R. et al. | 2011
- 578
-
The Role of Geobacterial Cytochromes In Uranium ReductionAwate, B.P. / Reguera, G. / Worden, R.M. et al. | 2011
- 579
-
Evaluation of Non-Growth Biokinetic Models for Chromate Reduction with ShewanellaeHsu, L. / Nealson, K.H. / Pirbazari, M. et al. | 2011
- 580
-
Detoxification of Coffee Pulp/Husk by Ligniculous Filamentous FungiDel Pilar Sierra-Gumez, M. / Ortiz-Bermedez, P. et al. | 2011
- 582
-
Detecting Biological Networks In Clostridium Thermocellum Using Computational ApproachesZhou, W. / Patil, V. et al. | 2011
- 583
-
Investigating the Mechanisms of Arsenic Removal by Microbial Layer In a Bio-Sand FilterGray, H. / Chan, C. / Ravindran, V. / Hsu, L. / Pirbazari, M. et al. | 2011
- 585
-
Intracellular Trafficking of Toll-Like Receptor 9 LigandsChen, H.C. / Shen, H. et al. | 2011
- 586
-
Toward a Quantitative and Predictive Model of Growth for An RNA VirusTimm, C.M. / Yin, J. et al. | 2011
- 587
-
Quantifying Metabolism of Differentiated Adipocytes Using 13C-Metabolic Flux AnalysisAntoniewicz, M.R. / Crown, S.B. / Marze, N. et al. | 2011
- 588
-
Systems-Level and Subcellular Resolution Dynamic Analysis of Trophectodermal Differentiation In Human Embryonic Stem CellsSarkar, P. / Randall, S.M. / Collier, T.S. / Muddiman, D.C. / Rao, B. et al. | 2011
- 589
-
Regulation of Mesenchymal Stem Cell Myogenic Differentiation by Cell-Cell Adhesion: The Role of Cadherins In DifferentiationAlimperti, S. / Andreadis, S.T. et al. | 2011
- 590
-
Efflux and Metabolism: Elucidating the Mechanisms of Metabolite Overflow and SecretionChubiz, L. / Rao, C.V. et al. | 2011
- 591
-
Single-Cell Analysis of Cellular Quality Control In S. Cerevisiae: How `Low' Can You Go?Young, C.L. / Yuraszeck, T. / Caplan, J. / Czymmek, K.J. / Doyle, F.J. / Robinson, A.S. et al. | 2011
- 593
-
The Free Energy of a Salt Bridge From SimulationsWhite, A.D. / Jiang, S. et al. | 2011
- 594
-
Molecular Dynamics Studies On the Forced Dissociation of Cucurbituril-Guest and Protein-Ligand Systems: Stress, Rupture Force and Binding AffinityVelez-Vega, C. / Gilson, M.K. et al. | 2011
- 596
-
Computational Discovery and Characterization of Peptide Chains That Recognize the tRNALys3 Anticodon LoopXiao, X. / Hall, C.K. / Agris, P. et al. | 2011
- 597
-
Effect of Local Sequence On the Genomic Positioning of NucleosomesFreeman, G.S. / Hinckley, D.M. / Ortiz, V. / Toepperwein, G.N. / De Pablo, J.J. et al. | 2011
- 599
-
Molecular Architecture of a Late 40S Ribosome Assembly IntermediateVashisth, H. / Brooks, C.L. et al. | 2011
- 600
-
Molecular Insight Into the Inhibition Effect of (-)-Epigallocatechin-3-Gallate On the Conformational Transition of Amyloid Peptide 42Liu, F. / Dong, X. / Sun, Y. et al. | 2011
- 601
-
Enhanced Meta-Analysis of Acetylcholine Binding Protein Structures Reveals Conformational Signatures of Agonism In Nicotinic ReceptorsStober, S.T. / Abrams, C.F. et al. | 2011
- 602
-
Re-Engineering Multicloning Sites for Function and ConvenienceCrook, N. / Freeman, E.S. / Alper, H. et al. | 2011
- 603
-
MetRxn: Reaction and Metabolite Standardization and Congruency Across Databases and Genome-Scale Metabolic ModelsSuthers, P. / Kumar, A. / Maranas, C.D. et al. | 2011
- 605
-
Modeling Metabolic Variation In Mutant Library Selections for Sugar UtilizationGroot, J. / Gill, R. et al. | 2011
- 606
-
Design Principles for 13C-Metabolic Flux Analysis Using Elementary Metabolite Unit Basis Vectors (EMU-BV)Antoniewicz, M.R. / Crown, S.B. et al. | 2011
- 607
-
Improving the Efficiency of 13C Isotopic Instationary Metabolic Flux AnalysisZhang, X. / Macintire, I. / Sriram, G. et al. | 2011
- 608
-
Cost Efficiency Model for the Network-Wide Quantitative Determination of Enzyme ActivitiesYang, H. / Libourel, I.G.L. et al. | 2011
- 609
-
Combining Experimental Data with Sampling Know-How: Large-Scale Kinetic Modeling of Chlamydomonas ReinhardtiiBollinger, J. / Castellanos, M. et al. | 2011
- 610
-
Evaluation of Escherichia Coli Proteins That Burden Recombinant Protein Purification On Inexpensive, Non-Affinity-Based ResinsBartlow, P.R. / Tiwari, N. / Beitle, R.R. / Ataai, M.M. et al. | 2011
- 611
-
Proteomics Approach for Predicting Separation Behavior of a Mixture of Proteins During Downstream PurificationSwanson, R.K. / Xu, R. / Nettleton, D.S. / Glatz, C.E. et al. | 2011
- 615
-
A Mathematical Model for Protein Purification with Affinity MembranesDimartino, S. / Boi, C. / Sarti, G.C. et al. | 2011
- 616
-
ELP-ZZ Fusions for the Purification of Immunoglobulins by Affinity PrecipitationMadan, B. / Chaudhary, G. / Cramer, S.M. / Chen, W. et al. | 2011
- 617
-
Reversible Oligomerization and Irreversible Coagulation of Monoclonal Antibodies In Downstream ProcessingArosio, P. / Rima, S. / Jaquet, B. / Muller-Spath, T. / Morbidelli, M. et al. | 2011
- 618
-
Effect of Feed Solution Properties On Viral Filtration PerformanceWalker, J. et al. | 2011
- 619
-
``Kinetically Limited'' Differential Centrifugation As An Inexpensive and Readily Available Alternative to Centrifugal ElutriationLee, B.-D. / Tan, J. / Polo-Parada, L. / Sengupta, S. et al. | 2011
- 620
-
Triggered Binding Activity of Anti-HER2/Neu Lipid Vesicles Encapsulating Doxorubicin Enhances Tumor Control In Vivo While Preserving the Potential for Low ToxicitiesBandekar, A. / Sofou, S. et al. | 2011
- 621
-
Sustained In Vivo Release From Imprinted Daily Wear Contact LensesTieppo, A. / White, C.J. / Paine, A.C. / Voyles, M.L. / McBride, M.K. / Byrne, M.E. et al. | 2011
- 622
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Hemodynamics-Driven Design of Carriers for Imaging and Drug Delivery In AtherosclerosisThompson, A. / Namdee, K. / Mocherla, S. / Mastria, E. / Bouis, D. / Eniola-Adefeso, O. et al. | 2011
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Impact of Food-Associated Stimuli On Barrier Properties of Gastrointestinal Mucus to Particle TransportYildiz, H.M. / Carrier, R. et al. | 2011
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Diffusion Coefficient Prediction Model for Sustained Release From Silk FilmsHines, D.J. / Kaplan, D.L. et al. | 2011
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The Mammalian MAPK/ERK Pathway Exhibits Properties of a Negative Feedback AmplifierSturm, O. / Orton, R. / Grindlay, J. / Birtwistle, M.R. / Vyshemirsky, V. / Gilbert, D. / Calder, M. / Pitt, A. / Kholodenko, B.N. / Kolch, W. et al. | 2011
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Quantifying Cross-Talk Among Interferon- gamma , Interleukin-12 and Tumor Necrosis Factor Signaling Pathways within a T~H1 Cell Model: A Model-Based Inference ApproachKlinke, D.J. / Chambers, E. / Cheng, N. et al. | 2011
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Reorientation During Cell Migration Occurs by a PI3K-Dependent Steering MechanismWelf, E.S. / Haugh, J. et al. | 2011
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A Mechanism Leading to Imbalanced EGFR Oncogenic Signaling Common to Lung and Brain Cancers with Distinct EGFR-Activating MutationsHall, J.M. / Furcht, C.M. / Rojas, A.M. / Lazzara, M.J. et al. | 2011
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Mitochondrial Dysfunction In Hepatic LipotoxicityEgnatchik, R. / Young, J. et al. | 2011
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Multisite Phosphorylation Underlies Ultrasensitive Response of CDK Inhibitor Sic1 In Yeast Cell Cycle RegulationVaredi K., S.M. / Song, H. / Hale, W.A. / Hakansson, K. / Lin, X.N. et al. | 2011
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Interpretation of Dynamic Signals: How Genes Respond When the Signal ChangesReeves, G.T. / Trisnadi, N. / Truong, T. / Nahmad, M. / Katz, S. / Stathopoulos, A. et al. | 2011
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In-Silico Design of Experiments As a Tool for Nonlinear Sensitivity Analysis of Detailed ModelsKiparissides, A. / Mantalaris, A. / Pistikopoulos, S. / Georgakis, C. et al. | 2011
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In Silico Prediction of Cancer GI50Whitebay, E.A. / Ramsey, J.D. / Neely, B.J. / Gasem, K.A.M. et al. | 2011
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A Mesoscopic Membrane Model for the Investigation of Mechanisms Underlaying Caveolae-Mediated EndocytosisAkpa, B.S. / Minshall, R.D. / Wedgewood, L.E. / Nitsche, L.C. et al. | 2011
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Modeling Heterogeneity In Populations of Self-Renewing Human Embryonic Stem CellsWu, J. / Tzanakakis, E.S. et al. | 2011
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Systematic Engineering Approach to Development and Identification of Physiologically-Based Pharmacokinetic ModelsHall, C. / Heitzig, M. / Sin, G. / Gani, R. / Linninger, A. et al. | 2011
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A Compartmentalized Sepsis Model Based On Neutrophil Kinetics As a Decision Supporting Tool of Therapeutic InterventionSong, S.O. / Hogg, J.S. / Parker, R.S. / Clermont, G. et al. | 2011
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A Lattice-Based Computational Model of Microscopic Bone Resorption In Cortical Bone Multicellular UnitsJeon, J. / Buenzli, P.R. / Pivonka, P. / Smith, D.W. / Cummings, P.T. et al. | 2011
- 646
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Optimal Control of Fed-Batch Fermentation Process Using Modified Iterative Dynamic ProgrammingLi, Z. / Karim, M.N. et al. | 2011
- 647
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Estimating the Free Energy of the Association of Amyloid Fibril Forming PeptidesShukla, D. / Trout, B.L. et al. | 2011
- 648
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The Role of Aromatic Residues In the Catalytic Domain Tunnel of Hypocrea Jecorina Cellobiohydrolase Cel6APayne, C.M. / Sammond, D.W. / Himmel, M.E. / Crowley, M.F. / Beckham, G.T. et al. | 2011
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Ultrasonic Stimulation of Chondrocytes: Harmonic Analysis Elucidates Frequency Dependent BioeffectsLouw, T. / Guhathakurta, S. / Subramanian, A. / Viljoen, H. et al. | 2011
- 650
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Exploring Virus Maturation Pathways Through Computer SimulationsMay, E.R. / Brooks, C.L. et al. | 2011
- 651
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Quantification of Sugar Binding Affinity and Study of Proton Translocation In Lactose Permease of Escherichia ColiPendse, P.Y. / Klauda, J. et al. | 2011
- 653
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Avoiding Macrophages: Design and Rationale Behind a `Marker of Self' PeptidePantano, D.A. / Klein, M.L. / Discher, D.E. et al. | 2011
- 654
-
Interaction Between PEG and Conjugated Insulin: A Molecular Dynamics Simulation and Experimental ObservationYang, C. / Wang, R. / Lu, D. / Liu, Z. et al. | 2011
- 655
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CMC Reviewer Expectations for ANDAs Using QbD ApproachesIser, R.L. et al. | 2011
- 656
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Mechanistic Models and Computer Software for Quality by Design In Formulation of Modified Release Dosage FormsWu, X.Y. / Zhou, Y. et al. | 2011
- 664
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Mechanistic Investigation of Drug Release From Asymmetric Membrane TabletsEnde, M.T.A. et al. | 2011
- 665
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QbD for Generic MR Drug ProductsTeng, Y. et al. | 2011
- 666
-
Fluid Bed Coating Process for Modified Release ApplicationsRubino, O. et al. | 2011
- 668
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Implementation of QbD In the Development of a CR Dosage FormSever, N.E. / Mackaplow, M.B. / Lefebvre, D. et al. | 2011
- 669
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Control Strategy for Manufacturing of Modified Release Capsules: A Regulatory PerspectiveSun, Z. et al. | 2011
- 670
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A Systems Approach to Decipher Stress Response Networks In MycobacteriaPrasanna, A.N. / Varusai, T.M. / Mehra, S. et al. | 2011
- 671
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Determination of Progerin Lamin A Phase Association and Orientation to Phospholipid MembranesKalinowski, A. / Yaron, P.N. / Lasche, M. / Dahl, K.N. et al. | 2011
- 672
-
CD47 Inhibit the Immune System Response Against Nanoparticles In VivoRodriguez, P.L. / Discher, D.E. et al. | 2011
- 673
-
Modeling of the Transcriptional Regulation of Tryptophan Hydroxylase In C. ElegansLee, H. / Lu, H. et al. | 2011
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-
On Damped Wave Diffusion of Oxygen In Iselts of Langergahns: Part-VI Comparison of Parabolic and Hyperbolic Models In a Finite Sphere for Pulse Boundary ConditionSharma, K.R. et al. | 2011
- 675
-
Experimental Analysis and Model-Based Optimization of Microalgae Growth in Photo-Bioreactors Using Flue GasHe, L. / Wu, G. / Tang, Y. et al. | 2011
- 676
-
Solvent-Enhanced Transformations of Steroids by Beauveria BassianaGonzalez, R. / Nicolau, F. / Olivo, H.F. / Peeples, T.L. et al. | 2011
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-
On Damped Wave Diffusion of Oxygen In Iselts of Langergahns: Part-VIII Comparison of Parabolic and Hyperbolic Models In a Finite Sphere Subject to Periodic Boundary ConditionSharma, K.R. et al. | 2011
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Toxicity, Transport, and Accumulation of Hydrocarbons In Saccharomyces CerevisiaeLing, H. / Chen, B. / Zhao, H. / Lim, P.Y. / Yaohari, H. / Leong, S. / Chang, M.W. et al. | 2011
- 679
-
Adiponectin Levels Mediate Recovery of Renal Function In a Novel Model of Podocyte AblationRutkowski, J.M. / Scherer, P.E. et al. | 2011
- 680
-
Assaying Secreted Titer of Heterologous Proteins In SalmonellaMetcalf, K.J. / Tullman-Ercek, D. et al. | 2011
- 681
-
Metabolic Engineering of Escherichia Coli for Dihomomethionine ProductionKang, A. / Chen, W. / Leong, S.S.J. / Ching, C.B. / Chang, M.W. et al. | 2011
- 682
-
Engineering E. Coli for Improved Efflux of Fuel MoleculesLeong, S.S.J. / Foo, J.L. / Chang, M.W. / Ching, C.B. et al. | 2011
- 683
-
Method for Using Peptide Labeling In Metabolic Flux AnalysisMandy, D. / Yang, H. / Allen, D.K. / Libourel, I.G.L. et al. | 2011
- 684
-
Do Bacteria Optimize Their Contact Area with Surfaces?Kargar, M. / Saucke, J.R. / Nain, A.S. / Behkam, B. et al. | 2011
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Engineering S. Cerevisiae for Production of Medium Chain HydrocarbonsLeong, S.S.J. / Lim, P.Y. / Yaohari, H. / Zhao, H. / Chen, B.B. / Ling, H. / Chang, M.W. et al. | 2011
- 686
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Collagen Binding Domain Fusion Proteins for Therapeutics: Fermentation and IsolationMoreland, H. / Fruchti, M. / Beitle, R.R. / Sakon, J. et al. | 2011
- 687
-
Effect of Surface Functional Groups On Interactions of Engineered Nanomaterials with a Lipid BilayerNegoda, A. / Baker, G. / Worden, R.M. et al. | 2011
- 688
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Effect of the Electrostatic Potential On the Internalization Mechanism of Cell Penetrating PeptidesFlores, K.A. / Salgado, J.C. / Zapata-Torres, G. / Gerdtzen, Z.P. / Gonzalez, M.J. / Hermoso, M.A. et al. | 2011
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Enhancement of Activity of Cross-Linked Enzyme Aggregates by a Novel Sugar-Assisted Precipitation StrategyWang, M. / Qi, W. / Su, R. / He, Z. et al. | 2011
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Inhibition and Deconstruction of Insulin Amyloid FibrillationLiu, R. / Su, R. / Qi, W. / He, Z. et al. | 2011
- 699
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Identification of Physically Unlinked Determinants of Complex PhenotypesGuo, Y. / Almario, M.P. / Kao, K. et al. | 2011
- 700
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Effects of Inoculation Methods On Fumaric Acid Fermentation by Rhizopus OryzaeZhang, K. / Yang, S.-T. et al. | 2011
- 701
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Structural Elucidation of Unknown Alkaloids Present In Catharanthus Roseus by Precursor Ion FingerprintingEspronceda, C.D.F. / Sander, G.W. / Perera, M.A. / Shanks, J.V. et al. | 2011
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Design and Use of Oligonucleotide Microarray Probes for Detection of Food-Borne Pathogenic Salmonella Enterica SerotypesShin, H.H. / Hwang, B.H. / Cha, H.J. et al. | 2011
- 703
-
Development of Brushite Bone Cement Using Recombinant Mussel Adhesive ProteinBahn, S.Y. / Choi, Y.S. / Cha, H.J. et al. | 2011
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Recombinant Shematrin: Silk-Like Protein From the OceanJung, D. / Yang, Y.J. / Kang, D.G. / Choi, Y.S. / Cha, H.J. et al. | 2011
- 705
-
Systems Biology of Glucose Metabolism In Humanized YeastVemuri, G. et al. | 2011
- 706
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Functional Nanofibers Fabricated by Mussel Adhesive Proteins for Tissue EngineeringKim, B.J. / Choi, Y.S. / Cha, H.J. et al. | 2011
- 707
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Marine Silk Protein From Sea AnemoneYang, Y.J. / Choi, Y.S. / Jung, D. / Cha, H.J. et al. | 2011
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Development of Lectin Immunoassay for Detection of Glyco-Chain Conjugated with BiomarkerEmori, Y. / Ohigashi, Y. / Kumada, Y. / Kishimoto, M. et al. | 2011
- 709
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A Mussel Adhesive Protein Fused with the BC Domain of Protein A Is a Functional Linker Material That Efficiently Immobilizes Antibodies Onto Diverse SurfacesKim, C.S. / Choi, Y.S. / Cha, H.J. et al. | 2011
- 710
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Production of Islet Cell Progeny From Human Pluripotent Stem Cells In Microcarrier CulturesWu, J. / Fan, Y. / Lock, L.T. / Tzanakakis, E.S. et al. | 2011
- 712
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Complete Cell-Free Conversion of Glucose to HydrogenRollin, J.A. / Zhang, P. et al. | 2011
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A Systemic Model for the Receptor Complex NRC/MASC Based On Its Inferred Interproteic NetworkCampos, J.A. / Gerdtzen, Z.P. / Salgado, J.C. et al. | 2011
- 718
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Cellulase Recycling and Reuse: Comparison of Immobilization, Ultrafiltration and Re-AdsorptionSu, R. / Qi, W. / He, Z. et al. | 2011
- 720
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Application of Hydroxyproline-O-Glycosylation Code for Enhanced Recombinant Protein Production In Plants and for Reconstruction of Plant Cell Wall for Improved Biomass ProcessabilityXu, J. / Ge, X. / Kieliszewski, M. et al. | 2011
- 721
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Effect of UV Curing On Peptide Antimicrobials and Considerations for Incorporation In Polymeric CoatingsAlim, F. / Neff, J.A. et al. | 2011
- 726
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Production of Lignocellulases by Trichoderma Viride In Free-Cell and Immobilized-Cell Fermentations: A Comparative Study of the SecretomeLan, T.-Q. / Yang, S.-T. / Wei, D. et al. | 2011
- 727
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Syngas Fermentation In Trickle Bed Reactor Using ``Clostridium Ragsdalei'' Strain P11Devarapalli, M. / Atiyeh, H.K. / Lewis, R.S. / Huhnke, R.L. et al. | 2011
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Effect of Propionyl-CoA Synthetase From Ralstonia Solanacearum by LC-MS/MS Quantification of Acyl-CoA Thioesters In Escherichia ColiArmando, J.W. / Pfeifer, B.A. et al. | 2011
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Developing a Miniaturized Assay for Label-Free, High-Throughput Biomolecule AnalysisJoffe, A.M. / Truong, T. / Ferguson, W.S. / Lo, R.C. et al. | 2011
- 730
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Analysis of Microbial Population Dynamics Using the Visualizing Evolution In Real Time (VERT) SystemWinkler, J.D. / Kao, K. et al. | 2011
- 731
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Metabolic Engineering of P. Freudenrichii for Enhanced Propionic Acid ProductionAmmar, E.M. / Yang, S.-T. et al. | 2011
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-
Computational and Thermodynamic Characterization of a Mostly Disordered Protein and An Aging Related MutantKalinowski, A.M. / Qin, Z. / Buehler, M.J. / Dahl, K.N. et al. | 2011
- 733
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Characterization of Short Chain Alcohol Dehydrogenases From Lactobacillus BrevisPugh, S. / Nielsen, D.R. et al. | 2011
- 734
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Integrating Functional Genomics Tools to Survey Retrovirus Production In Human CellsRodrigues, A.F. / Teixeira, A. / Carinhas, N. / Bandeira, V.S. / Alves, P.M. / Oliveira, R. / Hu, W.-S. / Coroadinha, A.S. et al. | 2011
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Inclusive Design of Flux-Determining 13C NMR ExperimentsMeade, J. / Khan, S.A. / Ataai, M.M. / Domach, M.M. et al. | 2011
- 737
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Pervaporative Separation of Bioethanol Using a Composite Hollow Fiber MembraneLee, H.-J. / Cho, E.-J. / Wi, S.-G. / Bae, H.-J. et al. | 2011
- 744
-
MicrobesFlux: A Web Based Platform for Reconstruction and Analysis of Genome-Scale Metabolic ModelsFeng, X. / Xu, Y. / Chen, Y. / Tang, Y.J. et al. | 2011
- 745
-
Mathematical Modeling of the Amensal Relation Between Pseudomonas Aeruginosa and Micrococcus Luteus - Experimental and Simulation StudiesSivaprakash, B. / Jayalakshmi, S. / Karunanithi, T. et al. | 2011
- 746
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Host Selection for Synthetic Pathways Using a Genome-Scale Model DatabaseNazem-Bokaee, H. / Senger, R.S. et al. | 2011
- 747
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Reverse Engineering the ``Small-World'' Gene NetworksGupta, P. / Garg, S. et al. | 2011
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Growth of B. Methanolicus MGA3 In Seawater-Based Media In a BioreactorPatel, A. / Yeary, J. / Komives, C.F. et al. | 2011
- 749
-
Confinement Can Destabilize Alpha-Helix Folding Proteins by Stabilizing the Beta StructuresJavidpour, L. / Sahimi, M. et al. | 2011