TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp. TC 1084 and Saccharothrix sp. TC 1094. I. Taxonomy, Fermentation, Isolation, and Biological Activities (English)
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JOURNAL OF ANTIBIOTICS
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52
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1069-1076
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1999
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ISSN:
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Title:TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp. TC 1084 and Saccharothrix sp. TC 1094. I. Taxonomy, Fermentation, Isolation, and Biological Activities
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Contributors:Koguchi, Y. ( author ) / Kohno, J. ( author ) / Suzuki, S.-I. ( author ) / Nishio, M. ( author ) / Takahashi, K. ( author ) / Ohnuki, T. ( author ) / Komatsubara, S. ( author )
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Published in:JOURNAL OF ANTIBIOTICS ; 52 ; 1069-1076
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Publication date:1999-01-01
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
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Table of contents – Volume 52
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1
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Original Articles - Beauveriolides, Specific Inhibitors of Lipid Droplet Formation in Mouse Macrophages, Produced by Beauveria sp FO-6979| 1999
- 1
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Beauveriolides, Specific Inhibitors of Lipid Droplet Formation in Mouse Macrophages, Produced by Beauveria sp. FO-6979Namatame, I. / Tomoda, H. / Si, S. / Yamaguchi, Y. / Masuma, R. / Omura, S. et al. | 1999
- 7
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Original Articles - Structure Elucidation of Fungal Beauveriolide III, a Novel Inhibitor of Lipid Droplet Formation in Mouse Macrophages| 1999
- 7
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Structure Elucidation of Fungal Beauveriolide III, a Novel Inhibitor of Lipid Droplet Formation in Mouse MacrophagesNamatame, I. / Tomoda, H. / Tabata, N. / Si, S. / Omura, S. et al. | 1999
- 13
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Original Articles - Brasilicardin A, a New Terpenoid Antibiotic from Pathogenic Nocardia brasiliensis: Fermentation, Isolation and Biological Activity| 1999
- 13
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Brasilicardin A, a New Terpenoid Antibiotic from Pathogenic Nocardia brasiliensis: Fermentation, Isolation and Biological ActivityKomaki, H. / Nemoto, A. / Tanaka, Y. / Takagi, H. / Yazawa, K. / Mikami, Y. / Shigemori, H. / Kobayashi, J. / Ando, A. / Nagata, Y. et al. | 1999
- 20
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Original Articles - IC202A, a New Siderophore with Immunosuppressive Activity Produced by Streptoalloteichus sp 1454-19 - I Taxonomy, Fermentation, Isolation and Biological Activity| 1999
- 20
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IC202a, a New Siderophore with Immunosuppressive Activity Produced by Streptoalloteichus sp. 1454-19. I. Taxonomy, Fermentation, Isolation and Biological ActivityIijima, M. / Someno, T. / Imada, C. / Okami, Y. / Ishizuka, M. / Takeuchi, T. et al. | 1999
- 25
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Original Articles - IC202A, a New Siderophore with Immunosuppressive Activity Produced by Streptoalloteichus sp 1454-19 - II Physico-chemical Properties and Structure Elucidation| 1999
- 25
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IC202a, a New Siderophore with Immunosuppressive Activity Produced by Streptoalloteichus sp. 1454-19. II. Physico-chemical Properties and Structure ElucidationIijima, M. / Someno, T. / Amemiya, M. / Sawa, R. / Naganawa, H. / Ishizuka, M. / Takeuchi, T. et al. | 1999
- 29
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Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp. K96-0670. I. Production, Isolation and Biological PropertiesZhang, H. / Tomoda, H. / Tabata, N. / Oohori, M. / Shinose, M. / Takahashi, Y. / Omura, S. et al. | 1999
- 29
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Original Articles - Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp K96-0670 - I Production, Isolation and Biological Properties| 1999
- 34
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Original Articles - Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp K96-0670 - II Structure Elucidation| 1999
- 34
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Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp. K96-0670. II. Structure ElucidationTabata, N. / Tomoda, H. / Zhang, H. / Uchida, R. / Omura, S. et al. | 1999
- 40
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Growth and Production Kinetics of a Teicoplanin Producing Strain of Actinoplanes teichomyceticusHeydorn, A. / Suhr-Jessen, T. / Nielsen, J. et al. | 1999
- 40
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Original Articles - Growth and Production Kinetics of a Teicoplanin Producing Strain of Actinoplanes teichomyceticus| 1999
- 45
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lmmunosuppressant Deoxyspergualin-induced Inhibition of Cell Proliferation is Accompanied with an Enhanced Reduction of Tetrazolium SaltOdaka, C. / Toyoda, E. / Nemoto, K. et al. | 1999
- 45
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Original Articles - Immunosuppressant Deoxyspergualin-induced Inhibition of Cell Proliferation is Accompanied with an Enhanced Reduction of Tetrazolium Salt| 1999
- 52
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Studies on Time-kill Kinetics of Different Classes of Antibiotics Against Veterinary Pathogenic Bacteria Including Pasteurella, Actinobacillus and Escherichia coilNorcia, L. J. L. / Silvia, A. M. / Hayashi, S. F. et al. | 1999
- 52
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Original Articles - Studies on Time-Kill Kinetics of Different Classes of Antibiotics Against Veterinary Pathogenic Bacteria Including Pasteurella, Actinobacillus and Escherichia coli| 1999
- 61
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Isolation and Structure of a New Antibiotic Viridomycin F Produced by Streptomyces sp. K96-0188Omura, S. / Enomoto, Y. / Shinose, M. / Takahashi, Y. / Iwai, Y. / Shiomi, K. et al. | 1999
- 61
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Notes - Isolation and Structure of a New Antibiotic Viridomycin F Produced by Streptomyces sp K96-0188| 1999
- 65
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Inhibitory Effect of Antimicrobial Agents on Alginate Production in Pseudomonas aeruginosaHosoyama, T. / Yuge, T. / Takahashi, S. / Suzuki, T. / Okubo, T. / Iyobe, S. / Nakagawa, A. et al. | 1999
- 65
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Notes - Inhibitory Effect of Antimicrobial Agents on Alginate Production in Pseudomonas aeruginosa| 1999
- 68
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New Derivatives of Tylosin IV Dihydro and Tetrahydro Desmycosin OximesNaranda, A. / Lopotar, N. et al. | 1999
- 68
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Notes - New Derivatives of Tylosin - IV Dihydro and Tetrahydro Desmycosin Oximes| 1999
- 71
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Communications to the Editor - Effects of Erythromycin and Its Derivatives on Interleukin-8 Release by Human Bronchial Epithelial Cell Line BEAS-2B Cells| 1999
- 71
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Effects of Erythromycin and Its Derivatives on Interleukin-8 Release by Human Bronchial Epithelial Cell Line Beas-2b CellsSunazuka, T. / Takizawa, H. / Desaki, M. / Suzuki, K. / Obata, R. / Otoguro, K. / Omura, S. et al. | 1999
- 75
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Original Articles - Phosphatoquinones A and B, Novel Tyrosine Phosphatase Inhibitors Produced by Streptomyces sp| 1999
- 75
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Phosphatoquinones A and B, Novel Tyrosine Phosphatase Inhibitors Produced by Streptomyces spKagamizono, T. / Hamaguchi, T. / Ando, T. / Sugawara, K. / Adachi, T. / Osada, H. et al. | 1999
- 81
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Original Articles - Purification and Characterization of 2-Deoxy-scyllo-inosose Synthase Derived from Bacillus circulans. A Crucial Carbocyclization Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics| 1999
- 81
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Purification and Characterization of 2-Deoxy-scyllo-inosose Synthase Derived from Bacillus circulans. A Crucial Carbocyclization Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside AntibioticsKudo, F. / Hosomi, Y. / Tamegai, H. / Kakinuma, K. et al. | 1999
- 89
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Isolation and Characterisation of a Prenylated p-Terphenyl Metabolite of Aspergillus candidus Possessing Potent and Selective Cytotoxic Activity; Studies on Mechanism of ActionStead, P. / Affleck, K. / Sidebottom, P. J. / Taylor, N. L. / Drake, C. S. / Todd, M. / Jowett, A. / Webb, G. et al. | 1999
- 89
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Original Articles - Isolation and Characterisation of a Prenylated p-Terphenyl Metabolite of Aspergillus candidus Possessing Potent and Selective Cytotoxic Activity; Studies on Mechanism of Action| 1999
- 96
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Original Articles - Biosynthesis of Polyketomycin Produced by Streptomyces diastatochromogenes Tü 6028| 1999
- 96
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Biosynthesis of Polyketomycin Produced by Streptomyces diastatochromogenes Tue 6028Paululat, T. / Zeeck, A. / Gutterer, J. M. / Fiedler, H.-P. et al. | 1999
- 102
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Production of Nikkomycins B~z and B~z by Mutasynthesis with Genetically Engineered Streptomyces tendae TUE901Bormann, C. / Kalmanczhelyi, A. / Suessmuth, R. / Jung, G. et al. | 1999
- 102
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Original Articles - Production of Nikkomycins Bx and Bz by Mutasynthesis with Genetically Engineered Streptomyces tendae TÜ901| 1999
- 109
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Bioconversion of Milbemycin-related Compounds: Biosynthetic Pathway of MilbemycinsNonaka, K. / Kumasaka, C. / Okamoto, Y. / Maruyama, F. / Yoshikawa, H. et al. | 1999
- 109
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Original Articles - Bioconversion of Milbemycin-related Compounds: Biosynthetic Pathway of Milbemycins| 1999
- 117
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Biosynthesis of the Pyrroindomycins by Streptomyces rugosporus LL-42D005; Characterization of Nutrient RequirementsAbbanat, D. / Maiese, W. / Greenstein, M. et al. | 1999
- 117
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Original Articles - Biosynthesis of the Pyrroindomycins by Streptomyces rugosporus LL-42D005; Characterization of Nutrient Requirements| 1999
- 127
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Time and Concentration Dependent Influence of Dirithromycin on Neutrophils Oxidative BurstLevert, H. / Gressier, B. / Brunet, C. / Dine, T. / Luyckx, M. / Ballester, L. / Templier, F. / Cazin, M. / Cazin, J. C. et al. | 1999
- 127
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Original Articles - Time and Concentration Dependent Influence of Dirithromycin on Neutrophils Oxidative Burst| 1999
- 134
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Original Articles - (--)-Phenylahistin Arrests Cells in Mitosis by Inhibiting Tubulin Polymerization| 1999
- 134
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( - )-Phenylahistin Arrests Cells in Mitosis by Inhibiting Tubulin PolymerizationKanoh, K. / Kohno, S. / Katada, J. / Takahashi, J. / Uno, I. et al. | 1999
- 142
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Original Articles - Structure-activity Relationships of Carbapenems to the Antagonism of the Antipseudomonal Activity of Other b-Lactam Agents and to the b-Lactamase Inducibility in Pseudomonas aeruginosa: Effects of 1b-Methyl Group and C-2 Side Chain| 1999
- 142
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Structure-activity Relationships of Carbapenems to the Antagonism of the Antipseudomonal Activity of Other -Lactam Agents and to the -Lactamase Inducibility in Pseudomonas aeruginosa: Effects of 1-Methyl Group and C-2 Side ChainKanazawa, K. / Nouda, H. / Sumita, Y. / Sunagawa, M. et al. | 1999
- 150
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First Total Synthesis of N-4909 and Its Diastereomer; A Stimulant of Apolipoprotein E Secretion in Human Hepatoma Hep G2 CellsYanai, M. / Hiramoto, S. et al. | 1999
- 150
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Original Articles - First Total Synthesis of N-4909 and Its Diastereomer; A Stimulant of Apolipoprotein E Secretion in Human Hepatoma Hep G2 Cells| 1999
- 160
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Original Articles - Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by Azaphilones| 1999
- 160
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Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by AzaphilonesTomoda, H. / Matsushima, C. / Tabata, N. / Namatame, I. / Tanaka, H. / Bamberger, M. J. / Arai, H. / Fukazawa, M. / Inoue, K. / Omura, S. et al. | 1999
- 171
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Notes - 11-Keto-9(E), 12(E)-octadecadienoic Acid, a Novel Fatty Acid that Enhances Fibrinolytic Activity of Endothelial Cells| 1999
- 171
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11-Keto-9(E),12(E)-octadecadienoic Acid, a Novel Fatty Acid that Enhances Fibrinolytic Activity of Endothelial CellsShinohara, C. / Hasumi, K. / Chikanishi, T. / Kikuchi, T. / Endo, A. et al. | 1999
- 175
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Notes - SNA-4606-1, a New Member of Elaiophylins with Enzyme Inhibition Activity Against Testosterone 5 a-Reductasen| 1999
- 175
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SNA-4606-1, a New Member of Elaiophylins with Enzyme Inhibition Activity Against Testosterone 5 -ReductaseNakakoshi, M. / Kimura, K.-I. / Nakajima, N. / Yoshihama, M. / Uramoto, M. et al. | 1999
- 178
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BE-40665D, a New Antibacterial Antibiotic Produced by an Actinoplanes spTsukamoto, M. / Nakajima, S. / Murooka, K. / Suzuki, H. / Hirayama, M. / Egawa, M. / Kondo, H. / Kojiri, K. / Suda, H. et al. | 1999
- 178
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Notes - BE40665D, a New Antibacterial Antibiotic Produced by an Actinoplanes sp| 1999
- 182
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Notes - Korormicin, an Antibiotic Specific for Gram-negative Marine Bacteria, Strongly Inhibits the Respiratory Chain-linked Na+-Translocating NADH: Quinone Reductase from the Marine Vibrio alginolyticus| 1999
- 182
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Korormicin, an Antibiotic Specific for Gram-negative Marine Bacteria, Strongly Inhibits the Respiratory Chain-linked Na^+-Translocating NADH: Quinone Reductase from the Marine Vibrio alginolyticusYoshikawa, K. / Nakayama, Y. / Hayashi, M. / Unemoto, T. / Mochida, K. et al. | 1999
- 186
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In Vitro Anti-methicillin-resistant Staphylococcus aureus Activity Found in Extracts of Marine Algae Indigenous to the Coastline of JapanHorikawa, M. / Noro, T. / Kamei, Y. et al. | 1999
- 186
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Notes - In Vitro Anti-methicillin-resistant Staphylococcus aureus Activity Found in Extracts of Marine Algae Indigenous to the Coastline of Japan| 1999
- 190
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Notes - Structural Elucidation of a Novel Erythromycin, 13-Cyclopentyl-13-desethyl-erythromycin B, from a Recombinant Saccharopolyspora erythraea Strain, NRRL 2338 pIG-1| 1999
- 190
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Structural Elucidation of a Novel Erythromycin, 13-Cyclopentyl-13-desethyl-erythromycin B, from a Recombinant Saccharopolyspora erythraea Strain, NRRL 2338 pIG/1Parsons, I. C. / Everett, J. R. / Pacey, M. S. / Ruddock, J. C. / Swanson, A. G. / Thompson, C. M. et al. | 1999
- 193
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Notes - Absolute Stereochemistry Determination of 16-Methyloxazolomycin Produced by a Streptomyces sp| 1999
- 193
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Absolute Stereochemistry Determination of 16-Methyloxazolomycin Produced by a Streptomyces spRyu, G. / Kim, S.-K. et al. | 1999
- 198
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Communication to the Editors - Adxanthromycin: A New Inhibitor of ICAM-1-LFA-1 Mediated Cell Adhesion from Streptomyces sp NA-148| 1999
- 198
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Adxanthromycin: A New Inhibitor of ICAM-1/LFA-1 Mediated Cell Adhesion from Streptomyces sp. NA-148Koiwa, T. / Nakano, T. / Takahashi, S. / Koshino, H. / Yamazaki, M. / Takashi, T. / Nakagawa, A. et al. | 1999
- 201
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Production of Erythromycin E by Pathogenic Nocardia brasiliensisMikami, Y. / Yazawa, K. / Nemoto, A. / Komaki, H. / Tanaka, Y. / Graefe, U. et al. | 1999
- 201
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Communication to the Editors - Production of Erythromycin E by Pathogenic Nocardia brasiliensis| 1999
- 215
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Asterriquinones Produced by Aspergillus candidus Inhibit Binding of the Grb-2 Adapter to Phosphorylated EGF Receptor Tyrosine KinaseAlvi, K. A. / Pu, H. / Luche, M. / Rice, A. / App, H. / McMahon, G. / Dare, H. / Margolis, B. et al. | 1999
- 215
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Original Articles - Asterriquinones Produced by Aspergillus candidus Inhibit Binding of the Grb-2 Adapter to Phosphorylated EGF Receptor Tyrosine Kinase| 1999
- 224
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A Novel Fungal Metabolite NG-061 Enhances and Mimics Neurotrophic Effect of Nerve Growth Factor (NGF) on Neurite Outgrowth in PC12 CellsIto, M. / Sakai, N. / Ito, K. / Mizobe, F. / Hanada, K. / Mizoue, K. / Bhandari, R. / Eguchi, T. / Kakinuma, K. et al. | 1999
- 224
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Original Articles - A Novel Fungal Metabolite NG-061 Enhances and Mimics Neurotrophic Effect of Nerve Growth Factor (NGF) on Neurite Outgrowth in PC12 Cells| 1999
- 231
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Original Articles - Structure of NG-061, a Novel Potentiator of Nerve Growth Factor (NGF) Isolated from Penicillium minioluteum F-4627| 1999
- 231
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Structure of NG-061, a Novel Potentiator of Nerve Growth Factor (NGF) Isolated from Penicillium minioluteum F-4627Bhandari, R. / Eguchi, T. / Sekine, A. / Ohashi, Y. / Kakinuma, K. / Ito, M. / Mizoue, K. et al. | 1999
- 235
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Original Articles - RP-1551s, a Family of Azaphilones Produced by Penicillium sp, Inhibit the Binding of PDGF to the Extracellular Domain of Its Receptor| 1999
- 235
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RP-1551S, a Family of Azaphilones Produced by Penicillium sp., Inhibit the Binding of PDGF to the Extracellular Domain of Its ReceptorToki, S. / Tanaka, T. / Uosaki, Y. / Yoshida, M. / Suzuki, Y. / Kita, K. / Mihara, A. / Ando, K. / Lokker, N. A. / Giese, N. A. et al. | 1999
- 245
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Original Articles - Glucolipsin A and B, Two New Glucokinase Activators Produced by Streptomyces purpurogeniscleroticus and Nocardia vaccinii| 1999
- 245
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Glucolipsin A and B, Two New Glucokinase Activators Produced by Streptomyces purpurogeniscleroticus and Nocardia vacciniiQian-Cutrone, J. / Ueki, T. / Huang, S. / Mookhtiar, K. A. / Ezekiel, R. / Kalinowski, S. / Brown, K. S. / Golik, J. / Lowe, S. / Pirnik, D. M. et al. | 1999
- 256
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Novel Naphthoquinones from a Streptomyces spKulanthaivel, P. / Perun, T. J. / Belvo, M. D. / Strobel, R. J. / Paul, D. C. / Williams, D. C. et al. | 1999
- 256
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Original Articles - Novel Naphthoquinones from a Streptomyces sp| 1999
- 263
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Gilvusmycin, a New Antitumor Antibiotic Related to CC-1065Tokoro, Y. / Isoe, T. / Shindo, K. et al. | 1999
- 263
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Original Articles - Gilvusmycin, a New Antitumor Antibiotic Related to CC-1065| 1999
- 269
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Original Articles - Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities| 1999
- 269
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Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological ActivitiesMatsumoto, N. / Tsuchida, T. / Maruyama, M. / Kinoshita, N. / Homma, Y. / Iinuma, H. / Sawa, T. / Hamada, M. / Takeuchi, T. / Heida, N. et al. | 1999
- 276
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Original Articles - Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4. II. Structure Determination| 1999
- 276
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Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4. II. Structure DeterminationMatsumoto, N. / Tsuchida, T. / Nakamura, H. / Sawa, R. / Takahashi, Y. / Naganawa, H. / Iinuma, H. / Sawa, T. / Takeuchi, T. / Shiro, M. et al. | 1999
- 281
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New Types of Liposidomycins Produced by Streptomyces that Inhibit Bacterial Peptidoglycan Synthesis. Structure Elucidation of Fatty Acid Components by Tandem Mass SpectrometryEsumi, Y. / Suzuki, Y. / Kimura, K.-I. / Yoshihama, M. / Ichikawa, T. / Uramoto, M. et al. | 1999
- 281
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Original Articles - New Types of Liposidomycins Produced by Streptomyces that Inhibit Bacterial Peptidoglycan Synthesis. Structure Elucidation of Fatty Acid Components by Tandem Mass Spectrometry| 1999
- 288
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Molecular Analysis of tlrB, an Antibiotic-resistance Gene from Tylosin-producing Streptomyces fradiae, and Discovery of a Novel Resistance MechanismWilson, V. T. W. / Cundliffe, E. et al. | 1999
- 288
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Original Articles - Molecular Analysis of tlrB, an Antibiotic-resistance Gene from Tylosin-producing Streptomyces fradiae, and Discovery of a Novel Resistance Mechanism| 1999
- 297
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Original Articles - Inhibition of Nitric Oxide Synthase Induction by 15-Deoxyspergualin in a Cultured Macrophage Cell Line, J744A.1 Activated with IFN-g and LPS| 1999
- 297
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Inhibition of Nitric Oxide Synthase Induction by 15-Deoxyspergualin in a Cultured Macrophage Cell Line, J744A. 1 Activated with IFN- and LPSNosaka, C. / Kunimoto, S. / Atsumi, S. / Takeuchi, T. et al. | 1999
- 305
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Original Articles - Mulundocandin, an Echinocandin-like Lipopeptide Antifungal Agent: Biological Activities In Vitro| 1999
- 305
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Mulundocandin, an Echinocandin-like Lipopeptide Antifungal Agent: Biological Activities In VitroHawser, S. / Borgonovi, M. / Markus, A. / Isert, D. et al. | 1999
- 311
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Original Articles - Aspirochlorine: A Highly Selective and Potent Inhibitor of Fungal Protein Synthesis| 1999
- 311
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Aspirochlorine: A Highly Selective and Potent Inhibitor of Fungal Protein SynthesisMonti, F. / Ripamonti, F. / Hawser, S. P. / Islam, K. et al. | 1999
- 319
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Chemical Modification of Antibiotic Eremomycin at the Asparagine Side ChainOlsufyeva, E. N. / Berdnikova, T. F. / Miroshnikova, O. V. / Reznikova, M. I. / Preobrazhenskaya, M. N. et al. | 1999
- 319
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Original Articles - Chemical Modification of Antibiotic Eremomycin at the Asparagine Side Chain| 1999
- 325
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Kitamycins, New Antimycin Antibiotics Produced by Streptomyces spHayashi, K.-I. / Nozaki, H. et al. | 1999
- 325
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Notes - Kitamycins, New Antimycin Antibiotics Produced by Streptomyces sp| 1999
- 329
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De-N-methylpamamycin-593A and B, New Pamamycin Derivatives Isolated from Streptomyces albonigerKozone, I. / Chikamoto, N. / Abe, H. / Natsume, M. et al. | 1999
- 329
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Notes - De-N-methylpamamycin-593A and B, New Pamamycin Derivatives Isolated from Streptomyces alboniger| 1999
- 332
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9-Hydroxyoudemansin A, a Novel Antifungal (E)--Methoxyacrylate from a Mycena speciesKleinwaechter, P. / Schlegel, B. / Dornberger, K. / Doerfelt, H. et al. | 1999
- 332
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Notes - 9-Hydroxyoudemansin A, a Novel Antifungal (E)-b-Methoxyacryhte from a Mycena species| 1999
- 335
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Notes - Inactivation of Fusidic Acid by Pathogenic Nocardia| 1999
- 335
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Inactivation of Fusidic Acid by Pathogenic NocardiaHarada, K.-I. / Tomita, K. / Fujii, K. / Sato, N. / Uchida, H. / Yazawa, K. / Mikami, Y. et al. | 1999
- 340
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Skeletal Structure of Neocopiamycin B from Streptomyces hygroscopicus var. crystallogenesFukai, T. / Kuroda, J. / Nomura, T. / Uno, J. / Akao, M. et al. | 1999
- 340
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Notes - Skeletal Structure of Neocopiamycin B from Streptomyces hygroscopicus var crystallogenes| 1999
- 345
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Notes - Synthesis of 1-Monoglycerides Having C11-20 Branched Chain Fatty Acids and Their Hemolysis Effects| 1999
- 345
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Synthesis of 1-Monoglycerides Having C~1~1~asymptotically equal to~2~0 Branched Chain Fatty Acids and Their Hemolysis EffectsPing, X. / Usuki, Y. / Akeda, Y. / Taniguchi, M. et al. | 1999
- 348
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A Facile Synthesis of D-Galactose-type Gem-Diamine 1-N-Iminosugar: A New Family of Galactosidase InhibitorShitara, E. / Nishimura, Y. / Kojima, F. / Takeuchi, T. et al. | 1999
- 348
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Communications to the Editor - A Facile Synthesis of D-Galactose-type Gem-Diamine 1-N-Iminosugar: A New Family of Galactosidase Inhibitor| 1999
- 363
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Lichenysins G, a Novel Family of Lipopeptide Biosurfactants from Bacillus licheniformis IM 1307: Production, Isolation and Structural Evaluation by NMR and Mass SpectrometryGrangemard, I. / Bonmatin, J.-M. / Bernillon, J. / Das, B. C. / Peypoux, F. et al. | 1999
- 363
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Production, Isolation and Structural Evaluation by NMR and Mass Spectrometry| 1999
- 374
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Feglymycin, a Novel Inhibitor of the Replication of the Human Immunodeficiency Virus. Fermentation, Isolation and Structure Elucidation| 1999
- 383
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Structure Elucidation of Sch 20562, a Glucosidic Cyclic Dehydropeptide Lactone - The Major Component of W-10 Antifungal Antibiotic| 1999
- 398
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Structure Elucidation of Sch 20561, a Cyclic Dehydropeptide Lactone -- A Major Component of W-10 Antifungal Antibiotic| 1999
- 407
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A New Enzyme, Edeine B~1 Amidinohydrolase, from Bacillus brevis TT02-8. Purification and Determination of the N-terminal Amino Acid SequenceShimotohno, K. W. / Iida, J. / Endo, T. et al. | 1999
- 407
-
Notes - A New Enzyme, Edeine B, Amidinohydrolase, from Bacillus brevis TT02-8. Purification and Determination of the N-terminal Amino Acid Sequence| 1999
- 412
-
Diazaphilonic Acid, a New Azaphilone with Telomerase Inhibitory ActivityTabata, Y. / Ikegami, S. / Yaguchi, T. / Sasaki, T. / Hoshiko, S. / Sakuma, S. / Shin-Ya, K. / Seto, H. et al. | 1999
- 412
-
Notes - Diazaphilonic Acid, a New Azaphilone with Telomerase Inhibitory Activity| 1999
- 415
-
C-1027 Enediyne Chromophore: Presence of Another Active Form and Its Chemical StructureOtani, T. / Yoshida, K.-I. / Sasaki, T. / Minami, Y. et al. | 1999
- 415
-
Notes - C-1027 Enediyne Chromophore: Presence of Another Active Form and Its Chemical Structure| 1999
- 422
-
Synthesis of an N-Methyl-D-aspartate Receptor Antagonist, ES-242-5, and Its AnalogsTatsuta, K. / Nagai, T. / Mase, T. / Yamazaki, T. / Tamura, T. et al. | 1999
- 422
-
Notes - Synthesis of an N-Methyl-D-aspartate Receptor Antagonist, ES-242-5, and Its Analogs| 1999
- 426
-
Communications to the Editor - Inhibition of Angiogenesis by a New Isocoumarin, NM-3| 1999
- 426
-
Inhibition of Angiogenesis by a New Isocoumarin, NM-3Nakashima, T. / Hirano, S.-I. / Agata, N. / Kumagai, H. / Isshiki, K. / Yoshioka, T. / Ishizuka, M. / Maeda, K. / Takeuchi, T. et al. | 1999
- 429
-
Communications to the Editor - Screening of Microbial Products Modifying the Action of Leptin (Obese Gene Product) by a Biosensor| 1999
- 429
-
Screening of Microbial Products Modifying the Action of Leptin (Obese Gene Product) by a BiosensorHidaka, T. / Morishita, T. / Shimotohno, K. W. / Endo, T. / Seto, H. / Noguchi, T. et al. | 1999
- 433
-
Absolute and Atropisomeric Structure of ES-242s, N-Methyl-D-aspartate Receptor AntagonistsTatsuta, K. / Nagai, T. / Mase, T. / Tamura, T. / Nakamura, H. et al. | 1999
- 433
-
Communications to the Editor - Absolute and Atropisomeric Structure of ES-242s, N-Methyl-D-aspartate Receptor Antagonists| 1999
- 449
-
High-mannose Type Oligosaccharide-dependent Apoptosis in U937 Cells Induced by Pradimicin, a Mannose-binding Antibiotic| 1999
- 449
-
Original Articles - High-mannose Type Oligosaccharide-dependent Apoptosis in U937 Cells Induced by Pradimicin, a Mannose-binding Antibiotic| 1999
- 455
-
Original Articles - Involvement of Ca2+ Ion and Reactive Oxygen Species as a Mediator in Pradimicin-induced Apoptosis| 1999
- 455
-
Involvement of Ca^2^+ Ion and Reactive Oxygen Species as a Mediator in Pradimicin-induced Apoptosis| 1999
- 460
-
Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520. III. Inhibitory Properties| 1999
- 460
-
Original Articles - Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No 1520. III. Inhibitory Properties| 1999
- 466
-
Original Articles - Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp A92-308110 - I. Taxonomy, Fermentation, Isolation and Biological Activity| 1999
- 466
-
Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp. A92-308110. I. Taxonomy, Fermentation, Isolation and Biological Activity| 1999
- 474
-
Original Articles - Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp A92-308110 - II. Structure Elucidation, Stereochemistry and Physico-chemical Properties| 1999
- 474
-
Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp. A92-308110. II. Structure Elucidation, Stereochemistry and Physico-chemical Properties| 1999
- 480
-
Original Articles - UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp 517-02 - IV. Comparative Studies of UK-2A with Antimycin A3 on Cytotoxic Activity and Reactive Oxygen Species Generation in LLC-PK1 Cells| 1999
- 480
-
UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. IV. Comparative Studies of UK-2A with Antimycin A~3 on Cytotoxic Activity and Reactive Oxygen Species Generation in LLC-PK1 Cells| 1999
- 485
-
Original Articles - Effect of Thiazinotrienomycin B, an Ansamycin Antibiotic, on the Function of Epidermal Growth Factor Receptor in Human Stomach Tumor Cells| 1999
- 485
-
Effect of Thiazinotrienomycin B, an Ansamycin Antibiotic, on the Function of Epidermal Growth Factor Receptor in Human Stomach Tumor Cells| 1999
- 491
-
Original Articles - AS-924, a Novel Bifunctional Prodrug of Ceftizoxime| 1999
- 491
-
AS-924, a Novel Bifunctional Prodrug of Ceftizoxime| 1999
- 501
-
New Members of the Macrosphelides from Microsphaeropsis sp. FO-5050 IV| 1999
- 501
-
Notes - New Members of the Macrosphelides from Microsphaeropsis sp FO-5050 IV| 1999
- 505
-
Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus| 1999
- 505
-
Notes - Novel Antibiotics Pyrisulfoxin A and B Produced by Streptomyces californicus| 1999
- 508
-
Communications to the Editor - A Novel Screen for the Detection of Chitin Acting Antifungal Compounds| 1999
- 525
-
Scyphostatin, a Neutral Sphingomyelinase Inhibitor from a Discomycete, Trichopeziza mollissima: Taxonomy of the Producing Organism, Fermentation, Isolation, and Physico-chemical Properties| 1999
- 525
-
Original Articles - Scyphostatin, a Neutral Sphingomyelinase Inhibitor from a Discomycete, Trichopeziza mollissima: Taxonomy of the Producing Organism, Fermentation, Isolation, and Physico-chemical Properties| 1999
- 531
-
Biological Activities of Scyphostatin, a Neutral Sphingomyelinase Inhibitor from a Discomycete, Trichopeziza mollissima| 1999
- 531
-
Original Articles - Biological Activities of Scyphostatin, a Neutral Sphingomyelinase Inhibitor from a Discomycete, Trichopeziza mollissima| 1999
- 536
-
Original Articles - WF14861, a New Cathepsins B and L Inhibitor Produced by Colletotrichum sp. I. Taxonomy, Production, Purification and Structure Elucidation| 1999
- 536
-
WF14861, a New Cathepsins B and L Inhibitor Produced by Colletotrichum sp. I. Taxonomy, Production, Purification and Structure Elucidation| 1999
- 542
-
Original Articles - WF14861, a New Cathepsins B and L Inhibitor Produced by Colletotrichum sp. II. Biological Properties| 1999
- 542
-
WF14861, a New Cathepsins B and L Inhibitor Produced by Colletotrichum sp. II. Biological Properties| 1999
- 548
-
Original Articles - Conagenin Derived from Streptomyces roseosporus Enhances Macrophage Functions| 1999
- 548
-
Conagenin Derived from Streptomyces roseosporus Enhances Macrophage Functions| 1999
- 552
-
Original Articles - Efficacy of Antibacterial Drugs in Mice with Complex Infection by Candida albicans and Escherichia coli| 1999
- 552
-
Efficacy of Antibacterial Drugs in Mice with Complex Infection by Candida albicans and Escherichia coli| 1999
- 559
-
Original Articles - Molecular Cloning of the Gene for the Key Carbocycle-forming Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminocyclitol Antibiotics and Its Comparison with Dehydroquinate Synthase| 1999
- 559
-
Molecular Cloning of the Gene for the Key Carbocycle-forming Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminocyclitol Antibiotics and Its Comparison with Dehydroquinate Synthase| 1999
- 572
-
Alutenusin, a Specific Neutral Sphingomyelinase Inhibitor, Produced by Penicillium sp. FO-7436| 1999
- 572
-
Notes - Alutenusin, a Specific Neutral Sphingomyelinase Inhibitor, Produced by Penicillium sp. FO-7436| 1999
- 575
-
TMC-169, a New Antibiotic of the Aspochalasin Group Produced by Aspergillus flavipes| 1999
- 575
-
Notes - TMC-169, a New Antibiotic of the Aspochalasin Group Produced by Aspergillus flavipes| 1999
- 578
-
Notes - Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Bodies of Fistulina hepatica| 1999
- 578
-
Cinnatriacetins A and B, New Antibacterial Triacetylene Derivatives from the Fruiting Bodies of Fistulina hepatica| 1999
- 582
-
Notes - Novel Nikkomycins Lx and Lz Produced by Genetically Engineered Streptomyces tendae Tü901| 1999
- 582
-
Novel Nikkomycins L~x and L~z Produced by Genetically Engineered Streptomyces tendae Tue901| 1999
- 586
-
Roselipins, Novel Fungal Metabolites Having a Highly Methylated Fatty Acid Modified with a Mannose and an Arabinitol| 1999
- 586
-
Communications to the Editor - Roselipins, Novel Fungal Metabolites Having a Highly Methylated Fatty Acid Modified with a Mannose and an Arabinitol| 1999
- 590
-
Communications to the Editor - Mer-f3, 12-Hydroxy-ovalicin, Produced by Metarrhizium sp. f3| 1999
- 590
-
Mer-f3, 12-Hydroxy-ovalicin, Produced by Metarrhizium sp. f3| 1999
- 607
-
TMC-66, a New Endothelin Converting Enzyme Inhibitor Produced by Streptomyces sp. A5008| 1999
- 607
-
Original Articles - TMC-66, a New Endothelin Converting Enzyme Inhibitor Produced by Streptomyces sp A5008| 1999
- 613
-
Antiviral and Hemolytic Activities of Surfactin Isoforms and Their Methyl Ester Derivatives| 1999
- 613
-
Original Articles - Antiviral and Hemolytic Activities of Surfactin Isoforms and Their Methyl Ester Derivatives| 1999
- 620
-
Original Articles - Bioconversion of Milbemycin-related Compounds: Isolation and Utilization of Non-producer, Strain RNBC-5-51| 1999
- 620
-
Bioconversion of Milbemycin-related Compounds: Isolation and Utilization of Non-producer, Strain RNBC-5-51| 1999
- 628
-
Original Articles - Mode of Action of Anhydrofulvic Acid against Candida utilis ATCC 42402 under Acidic Condition| 1999
- 628
-
Mode of Action of Anhydrofulvic Acid against Candida utilis ATCC 42402 under Acidic Condition| 1999
- 635
-
Original Articles - Cineromycins, g-Butyrolactones and Ansamycins by Analysis of the Secondary Metabolite Pattern Created by a Single Strain of Streptomyces| 1999
- 635
-
Cineromycins, -Butyrolactones and Ansamycins by Analysis of the Secondary Metabolite Pattern Created by a Single Strain of Streptomyces| 1999
- 643
-
Convergent Syntheses of Oral THF 1-Methylcarbapenems| 1999
- 643
-
Original Articles - Convergent Syntheses of Oral THF 1b-Methylcarbapenems| 1999
- 649
-
In Vitro Antibacterial Activity of FK041, a New Orally Active Cephalosporin| 1999
- 649
-
Original Articles - In Vitro Antibacterial Activity of FK041, a New Orally Active Cephalosporin| 1999
- 660
-
In Vivo Antibacterial Activity of FK041, a New Orally Active Cephalosporin| 1999
- 660
-
Original Articles - In Vivo Antibacterial Activity of FK041, a New Orally Active Cephalosporin| 1999
- 666
-
Notes - Isolation and Structural Elucidation of New Peptaibols, Bergofungins B, C and D, from Emericellopsis donezkii HKI 0059| 1999
- 666
-
Isolation and Structural Elucidation of New Peptaibols, Bergofungins B, C and D, from Emericellopsis donezkii HKI 0059| 1999
- 670
-
Notes - Macquarimicin A Inhibits Membrane-bound Neutral Sphingomyelinase from Rat Brain| 1999
- 670
-
Macquarimicin A Inhibits Membrane-bound Neutral Sphingomyelinase from Rat Brain| 1999
- 674
-
FK463, a Novel Water-soluble Echinocandin Lipopeptide: Synthesis and Antifungal Activity| 1999
- 674
-
Communications to the Editor - FK463, a Novel Water-soluble Echinocandin Lipopeptide: Synthesis and Antifungal Activity| 1999
- 689
-
Original Articles - Roselipins, Inhibitors of Diacylglycerol Acyltransferase, Produced by Gliociadium roseum KF-1040| 1999
- 689
-
Roselipins, Inhibitors of Diacylglycerol Acyltransferase, Produced by Gliocladium roseum KF-1040| 1999
- 695
-
Rhodopeptins (Mer-N1033), Novel Cyclic Tetrapeptides with Antifungal Activity from Rhodococcus sp. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities| 1999
- 695
-
Original Articles - Rhodopeptins (Mer-N1033), Novel Cyclic Tetrapeptides with Antifungal Activity from Rhodococcus sp - I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities| 1999
- 700
-
Rhodopeptins, Novel Cyclic Tetrapeptides with Antifungal Activities from Rhodococcus sp. II. Structure Elucidation| 1999
- 700
-
Original Articles - Rhodopeptins, Novel Cyclic Tetrapeptides with Antifungal Activities from Rhodococcus sp - II. Structure Elucidation| 1999
- 710
-
Original Articles - Rhodopeptins, Novel Cyclic Tetrapeptides with Antifungal Activities from Rhodococcus sp - III. Synthetic Study of Rhodopeptins| 1999
- 710
-
Rhodopeptins, Novel Cyclic Tetrapeptides with Antifungal Activities from Rhodococcus sp. III. Synthetic Study of Rhodopeptins| 1999
- 721
-
Melithiazols, New -Methoxyacrylate Inhibitors of the Respiratory Chain Isolated from Myxobacteria. Production, Isolation, Physico-chemical and Biological Properties| 1999
- 721
-
Original Articles - Melithiazols, New b-Methoxyacrylate Inhibitors of the Respiratory Chain Isolated from Myxobacteria - Production, Isolation, Physico-chemical and Biological Properties| 1999
- 730
-
Ala(0)-actagardine, a New Lantibiotic from Cultures of Actinoplanes liguriae ATCC 31048| 1999
- 730
-
Original Articles - Ala(0)-actagardine, a New Lantibiotic from Cultures of Actinoplanes liguriae ATCC 31048| 1999
- 742
-
Original Articles - Production of 6-Deoxy-13-cyclopropyl-Erythromycin B by Saccharopolyspora erythraea NRRL 18643| 1999
- 742
-
Production of 6-Deoxy-13-cyclopropyl-Erythromycin B by Saccharopolyspora erythraea NRRL 18643| 1999
- 748
-
UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. V. Inhibition Mechanism of Bovine Heart Mitochondrial Cytochrome bc~1 by the Novel Antibiotic UK-2A| 1999
- 748
-
Original Articles - UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp 517-02 - V. Inhibition Mechanism of Bovine Heart Mitochondrial Cytochrome bc1 by the Novel Antibiotic UK-2A| 1999
- 754
-
Novel Cyclopentanone Derivatives Pentenocins A and B, with Interleukin-1 Converting Enzyme Inhibitory Activity, Produced by Trichoderrna hamatum FO-6903| 1999
- 754
-
Notes - Novel Cyclopentanone Derivatives Pentenocins A and B, with Interleukin-1b Converting Enzyme Inhibitory Activity, Produced by Trichoderma hamatum FO-6903| 1999
- 758
-
Phenazostatin C, a New Diphenazine with Neuronal Cell Protecting Activity from Streptomyces sp.| 1999
- 758
-
Notes - Phenazostatin C, a New Diphenazine with Neuronal Cell Protecting Activity from Streptomyces sp| 1999
- 775
-
IC202B and C, New Siderophores with Immunosuppressive Activity Produced by Streptoalloteichus sp. 1454-19.| 1999
- 775
-
Original Articles - IC202B and C, New Siderophores with Immunosuppressive Activity Produced by Streptoalloteichus sp 1454-19| 1999
- 781
-
Decatromicins A and B, New Antibiotics Produced by Actinomadura sp. MK73-NF4. I. Taxonomy, Isolation, Physico-chemical Properties and Biological Activities.| 1999
- 781
-
Original Articles - Decatromicins A and B, New Antibiotics Produced by Actinomadura sp MK73-NF4 - I. Taxonomy, Isolation, Physico-chemical Properties and Biological Activities| 1999
- 787
-
Original Articles - Decatromicins A and B, New Antibiotics Produced by Actinomadura sp MK73-NF4 - II. Structure Determination| 1999
- 787
-
Decatromicins A and B, New Antibiotics Produced by Actinomadura sp. MK73-NF4. II Structure Determination.| 1999
- 797
-
Inhibition of Plasminogen Activator Inhibitor-1 by 11-Keto-9(E),12(E)-octadecadienoic Acid, a Novel Fatty Acid Produced by Trichoderma sp.| 1999
- 797
-
Original Articles - Inhibition of Plasminogen Activator Inhibitor-1 by 11-Keto-9(E), 12(E)-octadecadienoic Acid, a Novel Fatty Acid Produced by Trichoderma sp| 1999
- 803
-
Original Articles - The Decrease of Cytochrome c Oxidase Activity by 15-Deoxyspergualin Results in Enhancement of XTT Reduction in Cultured Cells| 1999
- 803
-
The Decrease of Cytochrome c Oxidase Activity by 15-Deoxyspergualin Results inEnhancement of XTT Reduction in Cultured Cells.| 1999
- 809
-
Original Articles - Enzymatic 1-N-Acetylation of Paromomycin by an Actinomycete Strain #8 with Multiple Aminoglycoside Resistance and Paromomycin Sensitivity| 1999
- 809
-
Enzymatic 1-N-Acetylatin of Paromomycin by an Actinomycete Strain #8 with Multiple Aminoglycoside Resistance and Paromomycin Sensitivity.| 1999
- 815
-
Original Articles - Structure Elucidation of Roselipins, Inhibitors of Diacylglycerol Acyltransferase Produced by Gliocladium roseum KF-1040| 1999
- 815
-
Structure Elucidation of Roselipins, Inhibitors ofDiacylglycerol Acyltransfrase Produced by Gliocladium roseum KF-1040.| 1999
- 827
-
Notes - F-11334s, New Inhibitors of Membrane-bound Neutral Sphingomyelinase| 1999
- 827
-
F-11334s, New Inhibitors of Membrane-bound Neutral Sphingomyelinase.| 1999
- 831
-
Preparation and In Vitro Antibacterial Activity of 6-O-Methylerythromycin D.| 1999
- 831
-
Notes - Preparation and In Vitro Antibacterial Activity of 6-O-Methylerythromycin D| 1999
- 835
-
Notes - Solid-Phase Synthesis of Cyclooctadepsipeptide N-4909 Using a Cyclization-Cleavage Method with Oxime Resin| 1999
- 835
-
Solid-Phase Synthesis of Cyclooctadepsipetide N-4909 Using a Cyclization-Cleavage Method with Oxime Resin.| 1999
- 851
-
Phenochalasins, Inhibitors of Lipid Droplet Formation in Mouse Macrophages, Produced by Phomopsis sp. FT-0211TOMODA, H. / NAMATAME, I. / SI, S. / KAWAGUCHI, K. / MASUMA, R. / NAMIKOSHI, M. / OMURA, S. et al. | 1999
- 851
-
Original Articles - Phenochalasins, Inhibitors of Lipid Droplet Formation in Mouse Macrophages, Produced by Phomopsis sp FT-0211| 1999
- 857
-
Structure Elucidation of Fungal Phenochalasins; Novel Inhibitors of Lipid Droplet Formation in Mouse Macrophages.TOMODA, H. / NAMATAME, I. / TABATA, N. / KAWAGUCHI, K. / SI, S. / OMURA, S. et al. | 1999
- 857
-
Original Articles - Structure Elucidation of Fungal Phenochalasins, Novel Inhibitors of Lipid Droplet Formation in Mouse Macrophages| 1999
- 862
-
Original Articles - A Novel (6S)-4,6-Dimethyldodeca-2E,4E-dienoyl Ester of Phomalactone and Related a-Pyrone Esters from it Phomopsis sp with Cytokine Production Inhibitory Activity| 1999
- 862
-
A Novel (6S)-4,6-Dimethyldodeca-2E,4E-dienoyl Ester of Phomalactone and Related alpha-Pyrone Esters from a Phomopsis sp. with Cytokine Production Inhibitory Activity.WRIGLEY, S. K. / SADEGHI, R. / BAHL, S. / WHITING, A. J. / AINSWORTH, A. M. / MARTIN, S. M. / KATZER, W. / FORD, R. / KAU, D. A. / ROBINSON, N. et al. | 1999
- 873
-
Vinylamycin, a New Depsipeptide Antibiotic, from Streptomyces sp.IGARASHI, M. / SHIDA, T. / SASAKI, Y. / KINOSHITA, N. / NAGANAWA, H. / HAMADA, M. / TAKEUCHI, T. et al. | 1999
- 873
-
Original Articles - Vinylamycin, a New Depsipeptide Antibiotic, from Streptomyces sp| 1999
- 880
-
Heme-dependent Radical Generation: Possible Involvement in Antimalarial Action of Non-peroxide Microbial Metabolites, Nanaomycin A and Radicicol.TANAKA, Y. / KAMEI, K. / OTOGURO, K. / OMURA, S. et al. | 1999
- 880
-
Original Articles - Heme-dependent Radical Generation: Possible Involvement in Antimalarial Action of Non-peroxide Microbial Metabolites, Nanaomycin A and Radicicol| 1999
- 889
-
Role of Aminoglycoside 6'-Acetyltransferase in a Novel Multiple Aminoglycoside Resistance of an Actinomycete Strain #8: Inactivation of Aminoglycosides with 6'-Amino Group Except Arbekacin and Neomycin.CHUN-BAO, Z. / SUNADA, A. / ISHIKAWA, J. / IKEDA, Y. / KONDO, S. / HOTTA, K. et al. | 1999
- 889
-
Original Articles - Role of Aminoglycoside 6'-Acetyltransferase in a Novel Multiple Aminoglycoside Resistance of an Actinomycete Strain #8: Inactivation of Aminoglycosides with 6'-Amino Group Except Arbekacin and Neomycin| 1999
- 895
-
Original Articles - A Mammalian Vector Carrying the Bleomycin N-Acetyltransferase Gene from Bleomycin-producing Streptomyces verticillus as a Selective Marker| 1999
- 895
-
A Mammalian Vector Carrying the Bleomycm N-Acetyltransferase Gene from Bleomycin-producing Streptomyces verticillus as a Selective Marker.SUGIYAMA, M. / TANAKA, M. / KUMAGAI, T. et al. | 1999
- 900
-
Original Articles - Synthesis and Biological Evaluation of New Oral Carbapenems with 1-Methyl-5-oxopyrrolidin-3-ylthio Moiety| 1999
- 900
-
Synthesis and Biological Evaluation of New Oral Carbapenems with 1-Methyl-5-oxopyrrolidin-3-ylthio Moiety.KANNO, O. / MIYAUCHI, M. / SHIBAYAMA, T. / OHYA, S. / KAWAMOTO, I. et al. | 1999
- 908
-
Original Articles - Synthesis and Antibacterial Activities of Novel 12-O-Methylerythromycin A Derivatives| 1999
- 908
-
Synthesis and Antibacterial Activities of Novel 12-O-Methylerythromycin A Derivatives.YI-YIN, K. / RILEY, D. / GRIEME, T. / NILIUS, A. et al. | 1999
- 913
-
Production, Isolation and Biological Properties of TMC-120A, B and C, Novel Inhibitors of Eosinophil Survival from Aspergillus ustus TC 1118.KOHNO, J. / SAKURAI, M. / KAMEDA, N. / NISHIO, M. / KAWANO, K. / KISHI, N. / OKUDA, T. / KOMATSUBARA, S. et al. | 1999
- 913
-
Notes - Production, Isolation and Biological Properties of TMC-120A, B and C, Novel Inhibitors of Eosinophil Survival from Aspergillus ustus TC 1118| 1999
- 917
-
Isolation and Characterization of Gibbestatin B, an Inhibitor of Gibberellin-induced Expression of alpha-Amylase, and Gibbestatin C from Streptomycetaes.KEN-ICHIRO, H. / NOZAKI, H. et al. | 1999
- 917
-
Notes - Isolation and Characterization of Gibbestatin B, an Inhibitor of Gibberellin-induced Expression of a-Amylase, and Gibbestatin C from Streptomycetaes| 1999
- 921
-
Indocarbazostatin, a Novel Inhibitor of NGF-induced Neurite Outgrowth from Rat Pheochromocytoma PC12 Cells.UBUKATA, M. / TAMEHIRO, N. / MATSUURA, N. / NAKAJIMA, N. et al. | 1999
- 921
-
Communications to the Editor - Indocarbazostatin, a Novel Inhibitor of NGF-induced Neurite Outgrowth from Rat Pheochromocytoma PC12 Cells| 1999
- 925
-
Communications to the Editor - Studies on the Biosynthesis of Bialaphos (SF-1293). 18. 2-Phosphinomethylmalic Acid Synthase: A Descendant of (R)-Citrate synthase?| 1999
- 925
-
Studies on the Biosynthesis of Bialaphos (SF-1293). 18. 2-Phosphinomethylmalic Acid Synthase: A Descendant of (R)-Citrate synthase?HIDAKA, T. / SHIMOTOHNO, K. W. / MORISHITA, T. / SETO, H. et al. | 1999
- 945
-
Original Articles - Biomolecular-chemical Screening - A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites. I. Screening Strategy and Validation| 1999
- 945
-
Biomolecular-chemical Screening. A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites. I. Screening Strategy and ValidationMaier, A. / Maul, C. / Zerlin, M. / Sattler, I. / Grabley, S. / Thiericke, R. et al. | 1999
- 945
-
A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites. I. Screening Strategy and Validation| 1999
- 952
-
Biomolecular-chemical Screening. A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites. II. Application Studies with Pure MetabolitesMaier, A. / Maul, C. / Zerlin, M. / Grabley, S. / Thiericke, R. et al. | 1999
- 952
-
Original Articles - Biomolecular-chemical Screening - A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites. II. Application Studies with Pure Metabolites| 1999
- 952
-
A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites. II. Application Studies with Pure Metabolites| 1999
- 960
-
Original Articles - Stresgenin B, an Inhibitor of Heat-induced Heat Shock Protein Gene Expression, Produced by Streptomyces sp AS-9| 1999
- 960
-
Stresgenin B, an Inhibitor of Heat-induced Heat Shock Protein Gene Expression, Produced by Streptomyces sp. AS-9Akagawa, H. / Takano, Y. / Ishii, A. / Mizuno, S. / Izui, R. / Sameshima, T. / Kawamura, N. / Dobashi, K. / Yoshioka, T. et al. | 1999
- 971
-
Original Articles - EM2487, a Novel Anti-HIV-1 Antibiotic, Produced by Streptomyces sp Mer-2487. Taxonomy, Fermentation, Biological Properties, Isolation and Structure Elucidation| 1999
- 971
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EM2487, a Novel Anti-HIV-1 Antibiotic, Produced by Streptomyces sp. Mer-2487. Taxonomy, Fermentation, Biological Properties, Isolation and Structure ElucidationTakeuchi, H. / Asai, N. / Tanabe, K. / Kozaki, T. / Fujita, M. / Sakai, T. / Okuda, A. / Naruse, N. / Yamamoto, S. / Sameshima, T. et al. | 1999
- 983
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Original Articles - Agrochelin, a New Cytotoxic Antibiotic from a Marine Agrobacterium. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity| 1999
- 983
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Agrochelin, a New Cytotoxic Antibiotic from a Marine Agrobacterium. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activity| 1999
- 988
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Original Articles - Memnobotrins and Memnoconols: Novel Metabolites from Memnoniella echinata| 1999
- 988
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Memnobotrins and Memnoconols: Novel Metabolites from Memnoniella echinata| 1999
- 998
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Tylopeptins A and B, New Antibiotic Peptides from Tylopilus neofelleus| 1999
- 998
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Original Articles - Tylopeptins A and B, New Antibiotic Peptides from Tylopilus neofelleus| 1999
- 1007
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Original Articles - In Vitro Microbiological Characterization of Novel Cyclic Homopentapeptides, CP-101,680 and CP-163,234, for Animal Health Use| 1999
- 1007
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In Vitro Microbiological Characterization of Novel Cyclic Homopentapeptides, CP-101,680 and CP-163,234, for Animal Health Use| 1999
- 1017
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Effective Production of Dehydro Cyclic Dipeptide Albonoursin Exhibiting Pronuclear Fusion Inhibitory Activity. I. Taxonomy and Fermentation| 1999
- 1017
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Original Articles - Effective Production of Dehydro Cyclic Dipeptide Albonoursin Exhibiting Pronuclear Fusion Inhibitory Activity - I. Taxonomy and Fermentation| 1999
- 1023
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Structures of Flagranones A, B and C, Cyclohexenoxide Antibiotics from the Nematode-trapping Fungus Duddingtonia flagrans| 1999
- 1023
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Original Articles - Structures of Flagranones A, B and C, Cyclohexenoxide Antibiotics from the Nematode-trapping Fungus Duddingtonia flagrans| 1999
- 1029
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Semisynthetic Derivatives of Madurahydroxylactone and Their Antibacterial Activities| 1999
- 1029
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Original Articles - Semisynthetic Derivatives of Madurahydroxylactone and Their Antibacterial Activities| 1999
- 1042
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Notes - Inhibition of Cholesteryl Ester Transfer Protein by Fungal Metabolites, L681,512| 1999
- 1042
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Inhibition of Cholesteryl Ester Transfer Protein by Fungal Metabolites, L681,512Tabata, N. / Tomoda, H. / Yamaguchi, Y. / Masuma, R. / Bamberger, M. J. / Omura, S. et al. | 1999
- 1046
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UCT1072s, New Antitumor Antibiotics with Topoisomerase II Mediated DNA Cleavage Activity, from Aspergillus spAsai, A. / Yamashita, Y. / Ando, K. / Kakita, S. / Kita, K. / Suzuki, Y. / Mihara, A. / Ashizawa, T. / Mizukami, T. / Nakano, H. et al. | 1999
- 1046
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Notes - UCT1072s, New Antitumor Antibiotics with Topoisomerase II Mediated DNA Cleavage Activity, from Aspergillus sp| 1999
- 1050
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Structural Modification of the Lincomycin Antibiotic| 1999
- 1050
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Notes - Structural Modification of the Lincomycin Antibiotic| 1999
- 1069
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Original Articles - TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp TC 1084 and Saccharothrix sp TC 1094 - I. Taxonomy, Fermentation, Isolation, and Biological Activities| 1999
- 1069
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TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp. TC 1084 and Saccharothrix sp. TC 1094. I. Taxonomy, Fermentation, Isolation, and Biological ActivitiesKoguchi, Y. / Kohno, J. / Suzuki, S.-I. / Nishio, M. / Takahashi, K. / Ohnuki, T. / Komatsubara, S. et al. | 1999
- 1077
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Production of a Family of Kinase-inhibiting Lactones from Fungal FermentationsDombrowski, A. / Jenkins, R. / Raghoobar, S. / Bills, G. / Polishook, J. / Pelaez, F. / Burgess, B. / Zhao, A. / Huang, L. / Zhang, Y. et al. | 1999
- 1077
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Original Articles - Production of a Family of Kinase-inhibiting Lactones from Fungal Fermentations| 1999
- 1086
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Original Articles - Resorcylic Acid Lactones: Naturally Occurring Potent and Selective Inhibitors of MEK| 1999
- 1086
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Resorcylic Acid Lactones: Naturally Occurring Potent and Selective Inhibitors of MEKZhao, A. / Lee, S. H. / Mojena, M. / Jenkins, R. G. / Patrick, D. R. / Huber, H. E. / Goetz, M. A. / Hensens, O. D. / Zink, D. L. / Vilella, D. et al. | 1999
- 1095
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Original Articles - Funalenone, a Novel Collagenase Inhibitor Produced by Aspergillus niger| 1999
- 1095
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Funalenone, a Novel Collagenase Inhibitor Produced by Aspergillus nigerInokoshi, J. / Shiomi, K. / Masuma, R. / Tanaka, H. / Yamada, H. / Omura, S. et al. | 1999
- 1101
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Ferroverdins, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Streptomyces sp. WK-5344. I. Production, Isolation and Biological PropertiesTomoda, H. / Tabata, N. / Shinose, M. / Takahashi, Y. / Woodruff, H. B. / Omura, S. et al. | 1999
- 1101
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Original Articles - Ferroverdins, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Streptomyces sp WK-5344 - I. Production, Isolation and Biological Properties| 1999
- 1108
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Original Articles - Ferroverdins, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Streptomyces sp WK-5344 - II. Structure Elucidation| 1999
- 1108
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Ferroverdins, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Streptomyces sp. WK-5344. II. Structure ElucidationTabata, N. / Tomoda, H. / Omura, S. et al. | 1999
- 1114
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TMC-171A, B, C and TMC-154, Novel Polyketide Antibiotics Produced by Gliocladium sp. TC 1304 and TC 1282Kohno, J. / Asai, Y. / Nishio, M. / Sakurai, M. / Kawano, K. / Hiramatsu, H. / Kameda, N. / Kishi, N. / Okuda, T. / Komatsubara, S. et al. | 1999
- 1114
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Original Articles - TMC-171A, B, C and TMC-154, Novel Polyketide Antibiotics Produced by Gliocladium sp TC 1304 and TC 1282| 1999
- 1124
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Biomolecular-chemical Screening: A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites. III. New DNA-binding MetabolitesMaul, C. / Sattler, I. / Zerlin, M. / Hinze, C. / Koch, C. / Maier, A. / Grabley, S. / Thiericke, R. et al. | 1999
- 1124
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Original Articles - Biomolecular-chemical Screening: A Novel Screening Approach for the Discovery of Biologically Active Secondary Metabolites - III. New DNA-binding Metabolites| 1999
- 1135
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Notes - Presence of Genes for b-Lactamases of Two Different Classes on a Single Plasmid from a Clinical Isolate of Serratia marcescens| 1999
- 1135
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Presence of Genes for beta-Lactamases of Two Different Classes on a Single Plasmid from a Clinical Isolate of Serratia marcescensYano, H. / Kuga, A. / Irinoda, K. / Okamoto, R. / Kobayashi, T. / Inoue, M. et al. | 1999
- 1140
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Synthesis and Properties of the Pyrrole Analogs of ChloramphenicolKrajewska, D. / Rozanski, A. et al. | 1999
- 1140
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Notes - Synthesis and Properties of the Pyrrole Analogs of Chloramphenicol| 1999
- 1143
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Notes - Tylosin Derivatives. V. Electrochemical Opening of Oxirane Ring| 1999
- 1143
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Tylosin Derivatives. V. Electrochemical Opening of Oxirane RingMandic, Z. / Naranda, A. / Lopotar, N. / Duic, L. / Ivekovic, D. / Tkalcec, M. et al. | 1999
- 1146
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The Total Synthesis and Absolute Structure of Antifungal Antibiotics (-)-PF1163A and BTatsuta, K. / Takano, S. / Ikeda, Y. / Nakano, S. / Miyazaki, S. et al. | 1999
- 1146
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Communications to the Editor - The Total Synthesis and Absolute Structure of Antifungal Antibiotics (-)-PF1163A and B| 1999
- 1152
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Synthesis and Biological Properties of a Novel Cephalosporin FR86521 Having Potent Activity Against Methicillin-resistant Staphylococcus aureus (MRSA)Kishi, K. / Ohki, H. / Okuda, S. / Kawabata, K. / Sakane, K. / Matsumoto, Y. / Matsumoto, S. / Tawara, S. et al. | 1999
- 1152
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Communications to the Editor - Synthesis and Biological Properties of a Novel Cephalosporin FR86521 Having Potent Activity Against Methicillin-resistant Staphylococcus aureus (MRSA)| 1999