Ligand Selectivity for the Acetylcholine Binding Site of the Rat alpha4beta2 and alpha3beta4 Nicotinic Subtypes Investigated by Molecular Docking (English)
- New search for: Bisson, W. H.
- New search for: Scapozza, L.
- New search for: Westera, G.
- New search for: Mu, L.
- New search for: Schubiger, P. A.
- New search for: Bisson, W. H.
- New search for: Scapozza, L.
- New search for: Westera, G.
- New search for: Mu, L.
- New search for: Schubiger, P. A.
In:
JOURNAL OF MEDICINAL CHEMISTRY
;
48
, 16
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5123-5130
;
2005
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ISSN:
- Article (Journal) / Print
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Title:Ligand Selectivity for the Acetylcholine Binding Site of the Rat alpha4beta2 and alpha3beta4 Nicotinic Subtypes Investigated by Molecular Docking
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Contributors:Bisson, W. H. ( author ) / Scapozza, L. ( author ) / Westera, G. ( author ) / Mu, L. ( author ) / Schubiger, P. A. ( author )
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Published in:JOURNAL OF MEDICINAL CHEMISTRY ; 48, 16 ; 5123-5130
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Publisher:
- New search for: ACS AMERICAN CHEMICAL SOCIETY
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Publication date:2005-01-01
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Size:8 pages
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ISSN:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 615
- Further information on Dewey Decimal Classification
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Classification:
DDC: 615 -
Source:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents – Volume 48, Issue 16
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 5059
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The Endocannabinoid System: Drug Targets, Lead Compounds, and Potential Therapeutic ApplicationsLambert, Didier M. / Fowler, Christopher J. et al. | 2005
- 5088
-
Design and Synthesis of Depeptidized Macrocyclic Inhibitors of Hepatitis C NS3-4A Protease Using Structure-Based Drug DesignVenkatraman, Srikanth / Njoroge, F. George / Girijavallabhan, Viyyoor M. / Madison, Vincent S. / Yao, Nanua H. / Prongay, Andrew J. / Butkiewicz, Nancy / Pichardo, John et al. | 2005
- 5092
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Synthesis and Structure−Activity Relationship of Novel 6-Aryl-1,4- dihydrobenzo[d][1,3]oxazine-2-thiones as Progesterone Receptor Modulators Leading to the Potent and Selective Nonsteroidal Progesterone Receptor Agonist Tanaproget #Fensome, Andrew / Bender, Reinhold / Chopra, Rajiv / Cohen, Jeff / Collins, Mark A. / Hudak, Valerie / Malakian, Karl / Lockhead, Susan / Olland, Andrea / Svenson, Kristine et al. | 2005
- 5096
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A Positron Emission Tomography Radioligand for the in Vivo Labeling of Metabotropic Glutamate 1 Receptor: (3-Ethyl-2-[11C]methyl-6-quinolinyl)(cis- 4-methoxycyclohexyl)methanoneHuang, Yiyun / Narendran, Raj / Bischoff, François / Guo, Ningning / Zhu, Zhihong / Bae, Sung-A / Lesage, Anne S. / Laruelle, Marc et al. | 2005
- 5100
-
Discovery of Potent Poly(ADP-ribose) Polymerase-1 Inhibitors from the Modification of Indeno[1,2-c]isoquinolinoneJagtap, Prakash G. / Baloglu, Erkan / Southan, Garry J. / Mabley, Jon G. / Li, Hongshan / Zhou, Jing / van Duzer, John / Salzman, Andrew L. / Szabó, Csaba et al. | 2005
- 5104
-
Design and Synthesis of Tricyclic Imidazo[4,5-b]pyridin-2-ones as Corticotropin-Releasing Factor-1 AntagonistsGuo, Zhiqiang / Tellew, John E. / Gross, Raymond S. / Dyck, Brian / Grey, Jonathan / Haddach, Mustapha / Kiankarimi, Mehrak / Lanier, Marion / Li, Bin-Feng / Luo, Zhiyong et al. | 2005
- 5108
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Discovery of Cell-Permeable Non-Peptide Inhibitors of beta-Secretase by High-Throughput Docking and Continuum Electrostatics CalculationsHuang, D. / Luthi, U. / Kolb, P. / Edler, K. / Cecchini, M. / Audetat, S. / Barberis, A. / Caflisch, A. et al. | 2005
- 5108
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Discovery of Cell-Permeable Non-Peptide Inhibitors of β-Secretase by High-Throughput Docking and Continuum Electrostatics Calculations #Huang, Danzhi / Lüthi, Urs / Kolb, Peter / Edler, Karin / Cecchini, Marco / Audetat, Stephan / Barberis, Alcide / Caflisch, Amedeo et al. | 2005
- 5108
-
Discovery of Cell-Permeable Non-Peptide Inhibitors of b-Secretase by High-Throughput Docking and Continuum Electrostatics CalculationsHuang, D. et al. | 2005
- 5112
-
A Novel Immunostimulator, N^2-[alpha-O-Benzyl-N-(acetylmuramyl)-L-alanyl-D-isoglutaminyl]-N^6-trans-(m-nitrocinnamoyl)-L-lysine, and Its Adjuvancy on the Hepatitis B Surface AntigenYang, H.-Z. / Xu, S. / Liao, X.-Y. / Zhang, S.-D. / Liang, Z.-L. / Liu, B.-H. / Bai, J.-Y. / Jiang, C. / Ding, J. / Cheng, G.-F. et al. | 2005
- 5112
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A Novel Immunostimulator, N2-(a-O-Benzyl-N-(acetylmuramyl)-l-alanyl-d- isoglutaminyl)-N6-trans-(m-nitrocinnamoyl)-l-lysine, and Its Adjuvancy on the Hepatitis B Surface AntigenYang, H.-Z. et al. | 2005
- 5112
-
A Novel Immunostimulator, N 2-[α-O-Benzyl-N-(acetylmuramyl)-l-alanyl-d- isoglutaminyl]-N 6-trans-(m-nitrocinnamoyl)-l-lysine, and Its Adjuvancy on the Hepatitis B Surface AntigenYang, Hong-Zhen / Xu, Song / Liao, Xue-Yan / Zhang, Suo-De / Liang, Zheng-Lun / Liu, Bai-He / Bai, Jin-Ye / Jiang, Chao / Ding, Jian / Cheng, Gui-Fang et al. | 2005
- 5123
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Ligand Selectivity for the Acetylcholine Binding Site of the Rat a4b2 and a3b4 Nicotinic Subtypes Investigated by Molecular DockingBisson, W.H. et al. | 2005
- 5123
-
Ligand Selectivity for the Acetylcholine Binding Site of the Rat α4β2 and α3β4 Nicotinic Subtypes Investigated by Molecular DockingBisson, William H. / Scapozza, Leonardo / Westera, Gerrit / Mu, Linjing / Schubiger, P. A. et al. | 2005
- 5123
-
Ligand Selectivity for the Acetylcholine Binding Site of the Rat alpha4beta2 and alpha3beta4 Nicotinic Subtypes Investigated by Molecular DockingBisson, W. H. / Scapozza, L. / Westera, G. / Mu, L. / Schubiger, P. A. et al. | 2005
- 5131
-
6-Aryl-8H-indeno[1,2-d]thiazol-2-ylamines: A1 Adenosine Receptor Agonist Allosteric Enhancers Having Improved PotencyChordia, Mahendra D. / Zigler, Molly / Murphree, Lauren J. / Figler, Heidi / Macdonald, Timothy L. / Olsson, Ray A. / Linden, Joel et al. | 2005
- 5140
-
Antifungal Agents. 11. N-Substituted Derivatives of 1-[(Aryl)(4-aryl-1H-pyrrol-3-yl)methyl]-1H-imidazole: Synthesis, Anti-Candida Activity, and QSAR StudiesDi Santo, Roberto / Tafi, Andrea / Costi, Roberta / Botta, Maurizo / Artico, Marino / Corelli, Federico / Forte, Michela / Caporuscio, Fabiana / Angiolella, Letizia / Palamara, Anna Teresa et al. | 2005
- 5154
-
A Rapid Computational Filter for Cytochrome P450 1A2 Inhibition Potential of Compound LibrariesChohan, Kamaldeep K. / Paine, Stuart W. / Mistry, Jaina / Barton, Patrick / Davis, Andrew M. et al. | 2005
- 5162
-
Novel, Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis, Structure−Activity Relationships, and Molecular Modeling StudiesDa Settimo, Federico / Primofiore, Giampaolo / La Motta, Concettina / Taliani, Sabrina / Simorini, Francesca / Marini, Anna Maria / Mugnaini, Laura / Lavecchia, Antonio / Novellino, Ettore / Tuscano, Daniela et al. | 2005
- 5175
-
Structure-Based Design, Synthesis, and Memapsin 2 (BACE) Inhibitory Activity of Carbocyclic and Heterocyclic PeptidomimeticsHanessian, Stephen / Yun, Hongying / Hou, Yihua / Yang, Gaoqiang / Bayrakdarian, Malken / Therrien, Eric / Moitessier, Nicolas / Roggo, Silvio / Veenstra, Siem / Tintelnot-Blomley, Marina et al. | 2005
- 5191
-
Application of Fluorescence Microscopy for Investigation of Cellular Distribution of Dinuclear Platinum Anticancer DrugsKalayda, Ganna V. / Zhang, Guofang / Abraham, Tsion / Tanke, Hans J. / Reedijk, Jan et al. | 2005
- 5203
-
Novel 17beta-Substituted Conformationally Constrained Neurosteroids that Modulate GABA~A ReceptorsSouli, C. / Avlonitis, N. / Calogeropoulou, T. / Tsotinis, A. / Maksay, G. / Biro, T. / Politi, A. / Mavromoustakos, T. / Makriyannis, A. / Reis, H. et al. | 2005
- 5203
-
Novel 17β-Substituted Conformationally Constrained Neurosteroids that Modulate GABAA ReceptorsSouli, Charikleia / Avlonitis, Nicolaos / Calogeropoulou, Theodora / Tsotinis, Andrew / Maksay, Gábor / Bíró, Tímea / Politi, Aggeliki / Mavromoustakos, Thomas / Makriyannis, Alexandros / Reis, Heribert et al. | 2005
- 5203
-
Novel 17b-Substituted Conformationally Constrained Neurosteroids that Modulate GABAA ReceptorsSouli, C. et al. | 2005
- 5215
-
Discovery and Structure−Activity Relationship of 3-Aryl-5-aryl-1,2,4-oxadiazoles as a New Series of Apoptosis Inducers and Potential Anticancer AgentsZhang, Han-Zhong / Kasibhatla, Shailaja / Kuemmerle, Jared / Kemnitzer, William / Ollis-Mason, Kristin / Qiu, Ling / Crogan-Grundy, Candace / Tseng, Ben / Drewe, John / Cai, Sui Xiong et al. | 2005
- 5224
-
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino)- phenylcarbamoylsulfanyl]propionic Acid and Its Derivatives as a Novel Class of Glutathione Reductase InhibitorsSeefeldt, Teresa / Dwivedi, Chandradhar / Peitz, Greg / Herman, Jocqueline / Carlson, Laura / Zhang, Zhiling / Guan, Xiangming et al. | 2005
- 5232
-
A Chiral Benzoquinolizine-2-carboxylic Acid Arginine Salt Active against Vancomycin-Resistant Staphylococcus a ureusde Souza, Noel J. / Gupte, Shrikant V. / Deshpande, Prasad K. / Desai, Vijaya N. / Bhawsar, Satish B. / Yeole, Ravindra D. / Shukla, Milind C. / Strahilevitz, Jacob / Hooper, David C. / Bozdogan, Bülent et al. | 2005
- 5243
-
A-Ring-Substituted Estrogen-3-O-sulfamates: Potent Multitargeted Anticancer AgentsLeese, Mathew P. / Hejaz, Hatem A. M. / Mahon, Mary F. / Newman, Simon P. / Purohit, Atul / Reed, Michael J. / Potter, Barry V. L. et al. | 2005
- 5257
-
Androsterone 3a-Ether-3b-Substituted and Androsterone 3b-Substituted Derivatives as Inhibitors of Type 3 17b-Hydroxysteroid Dehydrogenase: Chemical Synthesis and Structure-Activity RelationshipTchedam Ngatcha, B. et al. | 2005
- 5257
-
Androsterone 3α-Ether-3β-Substituted and Androsterone 3β-Substituted Derivatives as Inhibitors of Type 3 17β-Hydroxysteroid Dehydrogenase: Chemical Synthesis and Structure−Activity RelationshipTchédam Ngatcha, Béatrice / Luu-The, Van / Labrie, Fernand / Poirier, Donald et al. | 2005
- 5257
-
Androsterone 3alpha-Ether-3beta-Substituted and Androsterone 3beta-Substituted Derivatives as Inhibitors of Type 3 17beta-Hydroxysteroid Dehydrogenase: Chemical Synthesis and Structure-Activity RelationshipNgatcha, B. T. / Luu-The, V. / Labrie, F. / Poirier, D. et al. | 2005
- 5269
-
Syntheses and Biological Activities of Disaccharide DaunorubicinsZhang, Guisheng / Fang, Lanyan / Zhu, Lizhi / Aimiuwu, Josephine E. / Shen, Jie / Cheng, Hao / Muller, Mark T. / Lee, Gun Eui / Sun, Duxin / Wang, Peng George et al. | 2005
- 5279
-
Development of Dual-Acting Benzofurans for Thromboxane A2 Receptor Antagonist and Prostacyclin Receptor Agonist: Synthesis, Structure−Activity Relationship, and Evaluation of Benzofuran DerivativesOhno, Michihiro / Miyamoto, Mitsuko / Hoshi, Kazuhiro / Takeda, Takahiro / Yamada, Naohiro / Ohtake, Atsushi et al. | 2005
- 5295
-
Antidiabetic Activity of Passive Nonsteroidal Glucocorticoid Receptor ModulatorsLink, J. T. / Sorensen, Bryan / Patel, Jyoti / Grynfarb, Marlena / Goos-Nilsson, Annika / Wang, Jiahong / Fung, Steven / Wilcox, Denise / Zinker, Brad / Nguyen, Phong et al. | 2005
- 5305
-
Dipeptides as Effective Prodrugs of the Unnatural Amino Acid (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740), a Selective Group II Metabotropic Glutamate Receptor AgonistBueno, Ana Belén / Collado, Iván / de Dios, Alfonso / Domínguez, Carmen / Martín, José Alfredo / Martín, Luisa M. / Martínez-Grau, María Angeles / Montero, Carlos / Pedregal, Concepción / Catlow, John et al. | 2005
- 5321
-
Novel Fluorinated Prodrugs for Activation by Carboxypeptidase G2 Showing Good in Vivo Antitumor Activity in Gene-Directed Enzyme Prodrug TherapyDavies, Lawrence C. / Friedlos, Frank / Hedley, Douglas / Martin, Jan / Ogilvie, Lesley M. / Scanlon, Ian J. / Springer, Caroline J. et al. | 2005
- 5329
-
Synthesis of Classical, Four-Carbon Bridged 5-Substituted Furo(2,3-d)pyrimidine and 6-Substituted Pyrrolo(2,3-d)pyrimidine Analogues as Antifolates1Gangjee, A. et al. | 2005
- 5329
-
Synthesis of Classical, Four-Carbon Bridged 5-Substituted Furo[2,3-d]pyrimidine and 6-Substituted Pyrrolo[2,3-d]pyrimidine Analogues as AntifolatesGangjee, Aleem / Zeng, Yibin / McGuire, John J. / Kisliuk, Roy L. et al. | 2005
- 5337
-
High-Affinity Epidermal Growth Factor Receptor (EGFR) Irreversible Inhibitors with Diminished Chemical Reactivities as Positron Emission Tomography (PET)-Imaging Agent Candidates of EGFR Overexpressing TumorsMishani, Eyal / Abourbeh, Galith / Jacobson, Orit / Dissoki, Samar / Daniel, Revital Ben / Rozen, Yulia / Shaul, Mazal / Levitzki, Alexander et al. | 2005
- 5349
-
Designer Antibacterial Peptides Kill Fluoroquinolone-Resistant Clinical IsolatesOtvos,, Laszlo / Wade, John D. / Lin, Feng / Condie, Barry A. / Hanrieder, Joerg / Hoffmann, Ralf et al. | 2005
- 5360
-
Mechanism of Poly(acrylic acid) Acceleration of Antithrombin Inhibition of Thrombin: Implications for the Design of Novel Heparin MimicsMonien, Bernhard H. / Cheang, Kai I. / Desai, Umesh R. et al. | 2005
- 5369
-
Design and Synthesis of 4-(a-Hydroxymalonyl)phenylalanine as a New Phosphotyrosyl Mimetic and Its Use in Growth Factor Receptor Bound 2 Src-Homology 2 (Grb2 SH2) Domain-Binding PeptidesKang, S.-U. et al. | 2005
- 5369
-
Design and Synthesis of 4-(α-Hydroxymalonyl)phenylalanine as a New Phosphotyrosyl Mimetic and Its Use in Growth Factor Receptor Bound 2 Src-Homology 2 (Grb2 SH2) Domain-Binding PeptidesKang, Sang-Uk / Worthy, Karen M. / Bindu, Lakshman K. / Zhang, Manchao / Yang, Dajun / Fisher, Robert J. / Burke, Terrence R. et al. | 2005
- 5369
-
Design and Synthesis of 4-(alpha-Hydroxymalonyl)phenylalanine as a New Phosphotyrosyl Mimetic and Its Use in Growth Factor Receptor Bound 2 Src-Homology 2 (Grb2 SH2) Domain-Binding PeptidesKang, S.-U. / Worthy, K. M. / Bindu, L. K. / Zhang, M. / Yang, D. / Fisher, R. J. / Burke, T. R. et al. | 2005
- 5373
-
Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its EnantiomerAlbert, Rainer / Hinterding, Klaus / Brinkmann, Volker / Guerini, Danilo / Müller-Hartwieg, Constanze / Knecht, Helmut / Simeon, Corinne / Streiff, Markus / Wagner, Trixie / Welzenbach, Karl et al. | 2005
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-
Efficient Transfection of DNA by Liposomes Formulated with Cationic Gemini AmphiphilesBombelli, Cecilia / Faggioli, Francesca / Luciani, Paola / Mancini, Giovanna / Sacco, Maria Grazia et al. | 2005