Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11@b-hydroxysteroid dehydrogenase 1 inhibitors (English)
- New search for: Hofer, S.
- New search for: Kratschmar, D. V.
- New search for: Schernthanner, B.
- New search for: Vuorinen, A.
- New search for: Schuster, D.
- New search for: Odermatt, A.
- New search for: Easmon, J.
- New search for: Hofer, S.
- New search for: Kratschmar, D. V.
- New search for: Schernthanner, B.
- New search for: Vuorinen, A.
- New search for: Schuster, D.
- New search for: Odermatt, A.
- New search for: Easmon, J.
In:
BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS
;
23
, 19
;
5397-5400
;
2013
-
ISSN:
- Article (Journal) / Print
-
Title:Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11@b-hydroxysteroid dehydrogenase 1 inhibitors
-
Contributors:Hofer, S. ( author ) / Kratschmar, D. V. ( author ) / Schernthanner, B. ( author ) / Vuorinen, A. ( author ) / Schuster, D. ( author ) / Odermatt, A. ( author ) / Easmon, J. ( author )
-
Published in:BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS ; 23, 19 ; 5397-5400
-
Publisher:
- New search for: Elsevier Science B.V., Amsterdam.
-
Publication date:2013-01-01
-
Size:4 pages
-
ISSN:
-
Type of media:Article (Journal)
-
Type of material:Print
-
Language:English
- New search for: 572.5
- Further information on Dewey Decimal Classification
-
Classification:
DDC: 572.5 -
Source:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents – Volume 23, Issue 19
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 5249
-
Graphical contents list| 2013
- 5259
-
A high-yield route to synthesize the P-glycoprotein radioligand [11C]N-desmethyl-loperamide and its parent radioligand [11C]loperamideWang, Min / Gao, Mingzhang / Zheng, Qi-Huang et al. | 2013
- 5264
-
Synthesis and antiproliferative activity of new cytotoxic tri- and tetraazabenzo[3,2-a]fluorene-5,6-dione derivativesLeepasert, Theerachart / Shahabi, Manochehr / Shanab, Karem / Schirmer, Eva / Holzer, Wolfgang / Spreitzer, Helmut / Aicher, Babette / Müller, Gilbert / Günther, Eckhard et al. | 2013
- 5267
-
Systematic replacement of amides by 1,4-disubstituted[1,2,3]triazoles in Leu-enkephalin and the impact on the delta opioid receptor activityProteau-Gagné, Arnaud / Rochon, Kristina / Roy, Mélissa / Albert, Pierre-Julien / Guérin, Brigitte / Gendron, Louis / Dory, Yves L. et al. | 2013
- 5270
-
Solid-phase synthesis, characterization and RNAi activity of branch and hyperbranch siRNAsMaina, Anthony / Blackman, Brittany A. / Parronchi, Christopher J. / Morozko, Eva / Bender, Maria E. / Blake, Allan D. / Sabatino, David et al. | 2013
- 5275
-
Evaluation of the Influence of thiosemicarbazone–triazole hybrids on genes implicated in lipid oxidation and accumulation as potential anti-obesity agentsKinfe, Henok H. / Belay, Yonas H. / Joseph, Jitcy S. / Mukwevho, Emmanuel et al. | 2013
- 5279
-
Design, synthesis and biological evaluation of peptide derivatives of l-dopa as anti-parkinsonian agentsZhou, Tao / Hider, Robert C. / Jenner, Peter / Campbell, Bruce / Hobbs, Christopher J. / Rose, Sarah / Jairaj, Mark / Tayarani-Binazir, Kayhan A. / Syme, Alexander et al. | 2013
- 5283
-
Synthesis and antitumor activities of novel α-aminophosphonates dehydroabietic acid derivativesHuang, Xiao-Chao / Wang, Meng / Pan, Ying-Ming / Tian, Xiao-Yan / Wang, Heng-Shan / Zhang, Ye et al. | 2013
- 5283
-
Synthesis and antitumor activities of novel @a-aminophosphonates dehydroabietic acid derivativesHuang, X. C. / Wang, M. / Pan, Y. M. / Tian, X. Y. / Wang, H. S. / Zhang, Y. et al. | 2013
- 5290
-
Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitorsVacondio, Federica / Carmi, Caterina / Galvani, Elena / Bassi, Michele / Silva, Claudia / Lodola, Alessio / Rivara, Silvia / Cavazzoni, Andrea / Alfieri, Roberta R. / Petronini, Pier Giorgio et al. | 2013
- 5295
-
Rhodamine–propargylic esters for detection of mitochondrial hydrogen sulfide in living cellsChen, Xi / Wu, Shuqi / Han, Jiahuai / Han, Shoufa et al. | 2013
- 5300
-
Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective @b-site APP-cleaving enzyme 1 (BACE1) inhibitors: Structure based design and in vivo reduction of amyloid @b-peptidesRueeger, H. / Lueoend, R. / Machauer, R. / Veenstra, S. J. / Jacobson, L. H. / Staufenbiel, M. / Desrayaud, S. / Rondeau, J. M. / Mobitz, H. / Neumann, U. et al. | 2013
- 5300
-
Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: Structure based design and in vivo reduction of amyloid β-peptidesRueeger, Heinrich / Lueoend, Rainer / Machauer, Rainer / Veenstra, Siem Jacob / Jacobson, Laura Helen / Staufenbiel, Matthias / Desrayaud, Sandrine / Rondeau, Jean-Michel / Möbitz, Henrik / Neumann, Ulf et al. | 2013
- 5307
-
Doxorubicin-antioxidant co-drugsChegaev, Konstantin / Riganti, Chiara / Rolando, Barbara / Lazzarato, Loretta / Gazzano, Elena / Guglielmo, Stefano / Ghigo, Dario / Fruttero, Roberta / Gasco, Alberto et al. | 2013
- 5311
-
Phosphodiesterase inhibitors. Part 6: Design, synthesis, and structure–activity relationships of PDE4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory activityKojima, Akihiko / Takita, Satoshi / Sumiya, Tatsunobu / Ochiai, Koji / Iwase, Kazuhiko / Kishi, Tetsuya / Ohinata, Akira / Yageta, Yuichi / Yasue, Tokutaro / Kohno, Yasushi et al. | 2013
- 5317
-
Internal heavy atom effect of Au(III) and Pt(IV) on hypocrellin A for enhanced in vitro photodynamic therapy of cancerZhou, Lin / Ge, Xuefeng / Liu, Jihua / Zhou, Jiahong / Wei, Shaohua / Li, Fuyou / Shen, Jian et al. | 2013
- 5325
-
Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs)Mishra, Om P. / Simmons, Nicholas / Tyagi, Sonia / Pietrofesa, Ralph / Shuvaev, Vladimir V. / Valiulin, Roman A. / Heretsch, Philipp / Nicolaou, K.C. / Christofidou-Solomidou, Melpo et al. | 2013
- 5329
-
Synthesis and antiproliferative activities of quebecol and its analogsPericherla, Kasiviswanadharaju / Shirazi, Amir Nasrolahi / Kameshwara Rao, V. / Tiwari, Rakesh K. / DaSilva, Nicholas / McCaffrey, Kellen T. / Beni, Yousef A. / González-Sarrías, Antonio / Seeram, Navindra P. / Parang, Keykavous et al. | 2013
- 5332
-
Design, synthesis and ex vivo evaluation of colon-specific azo based prodrugs of anticancer agentsSharma, Rajiv / Rawal, Ravindra K. / Gaba, Tripti / Singla, Nishu / Malhotra, Manav / Matharoo, Sahil / Bhardwaj, T.R. et al. | 2013
- 5339
-
Molecular design of new aggrecanases-2 inhibitorsShan, Zhi Jie / Zhai, Hong Lin / Huang, Xiao Yan / Li, Li Na / Zhang, Xiao Yun et al. | 2013
- 5351
-
Optimization of anti-proliferative activity using a screening approach with a series of bis-heterocyclic G-quadruplex ligandsOhnmacht, Stephan A. / Ciancimino, Cristina / Vignaroli, Giulia / Gunaratnam, Mekala / Neidle, Stephen et al. | 2013
- 5356
-
C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: Effects of conjugation to cholesterol and side chain–side chain crosslinkingHiggins, Chelsea D. / Koellhoffer, Jayne F. / Chandran, Kartik / Lai, Jonathan R. et al. | 2013
- 5361
-
Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine (23)Biftu, Tesfaye / Qian, Xiaoxia / Chen, Ping / Feng, Dennis / Scapin, Giovanna / Gao, Ying-Duo / Cox, Jason / Sinha Roy, Ranabir / Eiermann, George / He, Huabing et al. | 2013
- 5367
-
Analogues of the Inhoffen–Lythgoe diol with anti-proliferative activityDeBerardinis, Albert M. / Lemieux, Steven / Hadden, M. Kyle et al. | 2013
- 5371
-
Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcriptionXie, Fuchun / Li, Bingbing X. / Broussard, Candice / Xiao, Xiangshu et al. | 2013
- 5376
-
β2-Adrenoceptor agonists in the regulation of mitochondrial biogenesisPeterson, Yuri K. / Cameron, Robert B. / Wills, Lauren P. / Trager, Richard E. / Lindsey, Chris C. / Beeson, Craig C. / Schnellmann, Rick G. et al. | 2013
- 5376
-
@b"2-Adrenoceptor agonists in the regulation of mitochondrial biogenesisPeterson, Y. K. / Cameron, R. B. / Wills, L. P. / Trager, R. E. / Lindsey, C. C. / Beeson, C. C. / Schnellmann, R. G. et al. | 2013
- 5382
-
Molecular docking studies of the interaction between propargylic enol ethers and human DNA topoisomerase II@aSilveira-Dorta, G. / Sousa, I. J. / Rios-Luci, C. / Martin, V. S. / Fernandes, M. X. / Padron, J. M. et al. | 2013
- 5382
-
Molecular docking studies of the interaction between propargylic enol ethers and human DNA topoisomerase IIαSilveira-Dorta, Gastón / Sousa, Inês J. / Ríos-Luci, Carla / Martín, Víctor S. / Fernandes, Miguel X. / Padrón, José M. et al. | 2013
- 5385
-
Four-membered heterocycles-containing 4-anilino-quinazoline derivatives as epidermal growth factor receptor (EGFR) kinase inhibitorsZhao, Feng / Lin, Zhaohu / Wang, Feng / Zhao, Weili / Dong, Xiaochun et al. | 2013
- 5389
-
Donor specificity and regioselectivity in Lipolase mediated acylations of methyl @a-d-glucopyranoside by vinyl esters of phenolic acids and their analoguesMastihubova, M. / Mastihuba, V. et al. | 2013
- 5389
-
Donor specificity and regioselectivity in Lipolase mediated acylations of methyl α-d-glucopyranoside by vinyl esters of phenolic acids and their analoguesMastihubová, Mária / Mastihuba, Vladimír et al. | 2013
- 5393
-
Design, synthesis and antitubercular evaluation of novel 2-substituted-3H-benzofuro benzofurans via palladium–copper catalysed Sonagashira coupling reactionYempala, Thirumal / Sridevi, Jonnalagadda Padma / Yogeeswari, Perumal / Sriram, Darmarajan / Kantevari, Srinivas et al. | 2013
- 5397
-
Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11β-hydroxysteroid dehydrogenase 1 inhibitorsHofer, Sandra / Kratschmar, Denise V. / Schernthanner, Brigitte / Vuorinen, Anna / Schuster, Daniela / Odermatt, Alex / Easmon, Johnny et al. | 2013
- 5397
-
Synthesis and biological analysis of benzazol-2-yl piperazine sulfonamides as 11@b-hydroxysteroid dehydrogenase 1 inhibitorsHofer, S. / Kratschmar, D. V. / Schernthanner, B. / Vuorinen, A. / Schuster, D. / Odermatt, A. / Easmon, J. et al. | 2013
- 5401
-
Fragment-based discovery of focal adhesion kinase inhibitorsGrädler, Ulrich / Bomke, Jörg / Musil, Djordje / Dresing, Verena / Lehmann, Martin / Hölzemann, Günter / Greiner, Hartmut / Esdar, Christina / Krier, Mireille / Heinrich, Timo et al. | 2013
- 5410
-
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptorMcClure, Kim F. / Jackson, Margaret / Cameron, Kimberly O. / Kung, Daniel W. / Perry, David A. / Orr, Suvi T.M. / Zhang, Yingxin / Kohrt, Jeffrey / Tu, Meihua / Gao, Hua et al. | 2013
- 5415
-
Investigation of an F-18 oxytocin receptor selective ligand via PET imagingSmith, Aaron L. / Freeman, Sara M. / Voll, Ronald J. / Young, Larry J. / Goodman, Mark M. et al. | 2013
- 5421
-
Discovery of novel (1S)-(−)-verbenone derivatives with anti-oxidant and anti-ischemic effectsJu, Chung / Song, Sumi / Hwang, Sunyoung / Kim, Chorong / Kim, Minkyoung / Gu, Jail / Oh, Yu-Kyoung / Lee, Kyeong / Kwon, Jinsun / Lee, Kiho et al. | 2013
- 5426
-
Substituted pyrrolo[2,3-d]pyrimidines as Cryptosporidium hominis thymidylate synthase inhibitorsKumar, Vidya P. / Frey, Kathleen M. / Wang, Yiqiang / Jain, Hitesh K. / Gangjee, Aleem / Anderson, Karen S. et al. | 2013
- 5429
-
Design, synthesis and biological studies of Survivin Dimerization Modulators that prolong mitotic cycleChettiar, Somsundaram N. / Cooley, James V. / Park, In-Hee / Bhasin, Deepak / Chakravarti, Arnab / Li, Pui-Kai / Li, Chenglong / Jacob, Naduparambil Korah et al. | 2013
- 5434
-
Anticholinesterase insecticide action at the murine male reproductive systemNoro, Yuki / Tomizawa, Motohiro / Ito, Yuki / Suzuki, Himiko / Abe, Keisuke / Kamijima, Michihiro et al. | 2013
- 5437
-
Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerasesMiles, Timothy J. / Hennessy, Alan J. / Bax, Ben / Brooks, Gerald / Brown, Barry S. / Brown, Pamela / Cailleau, Nathalie / Chen, Dongzhao / Dabbs, Steven / Davies, David T. et al. | 2013
- 5442
-
Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonistsSheppeck, James E. II / Gilmore, John L. / Xiao, Hai-Yun / Dhar, T.G. Murali / Nirschl, David / Doweyko, Arthur M. / Sack, Jack S. / Corbett, Martin J. / Malley, Mary F. / Gougoutas, Jack Z. et al. | 2013
- 5448
-
Synthesis and structure–activity relationships of novel indazolyl glucocorticoid receptor partial agonistsGilmore, John L. / Sheppeck, James E. II / Wang, Jim / Dhar, T.G. Murali / Cavallaro, Cullen / Doweyko, Arthur M. / Mckay, Lorraine / Cunningham, Mark D. / Habte, Sium F. / Nadler, Steven G. et al. | 2013
- 5452
-
Corrigendum to “Two dimeric lignans with an unusual α,β-unsaturated ketone motif from Zanthoxylum podocarpum and their inhibitory effects on nitric oxide production” [Bioorg. Med. Chem. Lett. 21 (2011) 373–376]Zhou, Xiao-Jiang / Chen, Xiao-Liang / Li, Xue-Song / Su, Jia / He, Jiang-Bo / Wang, Yue-Hu / Li, Yan / Cheng, Yong-Xian et al. | 2013
- 5452
-
Corrigendum to ''Two dimeric lignans with an unusual @a,@b-unsaturated ketone motif from Zanthoxylum podocarpum and their inhibitory effects on nitric oxide production'' [Bioorg. Med. Chem. Lett. 21 (2011) 373-376]Zhou, X. J. / Chen, X. L. / Li, X. S. / Su, J. / He, J. B. / Wang, Y. H. / Li, Y. / Cheng, Y. X. et al. | 2013
- 5453
-
Corrigendum to “Design, synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing methyl ferulate” [Bioorg. Med. Chem. Lett. 23 (2013) 2089–2092]Yang, Xiao-Zhi / Diao, Xiao-Juan / Yang, Wen-Hui / Li, Feng / He, Guang-Wei / Gong, Guo-Qing / Xu, Yun-Gen et al. | 2013
- IFC
-
Editorial board| 2013