P-Glycoprotein Activity Is Non-Monotonically Modulated by Transmembrane Voltage (English)
- New search for: Schroeder, Thomas B.H.
- New search for: Liu, Haiyan
- New search for: Sept, David
- New search for: Kapoor, Khyati
- New search for: Rao, Divya K.
- New search for: Ambudkar, Suresh V.
- New search for: Mayer, Michael
- New search for: Schroeder, Thomas B.H.
- New search for: Liu, Haiyan
- New search for: Sept, David
- New search for: Kapoor, Khyati
- New search for: Rao, Divya K.
- New search for: Ambudkar, Suresh V.
- New search for: Mayer, Michael
In:
Biophysical journal
;
116
, s1
;
126a
;
2019
-
ISSN:
- Article (Journal) / Print
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Title:P-Glycoprotein Activity Is Non-Monotonically Modulated by Transmembrane Voltage
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Contributors:Schroeder, Thomas B.H. ( author ) / Liu, Haiyan ( author ) / Sept, David ( author ) / Kapoor, Khyati ( author ) / Rao, Divya K. ( author ) / Ambudkar, Suresh V. ( author ) / Mayer, Michael ( author )
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Published in:Biophysical journal ; 116, s1 ; 126a
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Publisher:
- New search for: Elsevier Science B.V., Amsterdam
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Publication date:2019-01-01
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Size:126a
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ISSN:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 571.4
- Further information on Dewey Decimal Classification
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Classification:
DDC: 571.4 -
Source:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents – Volume 116, Issue s1
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2a
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Ketone Bodies and their Polymers in Heart Failure and Type 2 Diabetes: Lessons Learned from the Ketone Ester DietThai, Phung N. / Demirkhanyan, Lusine / King, M. Todd / Zakharian, Eleonora / Veech, Richard / Schaefer, Saul / Bers, Donald M. / Dedkova, Elena N. et al. | 2019
- 3a
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The Effect of Nucleosome Conformation on Histone Tail Binding and SpecificityMorrison, Emma A. / Bowerman, Samuel / Wereszczynski, Jeff / Musselman, Catherine et al. | 2019
- 4a
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Illuminating the Black Box of DNA-Protein InteractionsLeake, Mark C. et al. | 2019
- 7a
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Nanophotonic Tools to Resolve Nanoscale Dynamics on Biological MembranesGarcia-Parajo, Maria et al. | 2019
- 8a
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A Myosin II Nanomachine Mimicking the Striated MuscleBianco, Pasquale / Pertici, Irene / Bongini, Lorenzo / Bianchi, Giulio / Cojoc, Dan / Kellermayer, Miklós S. / Lombardi, Vincenzo et al. | 2019
- 9a
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Context and Complexity: How Ionic Conductances Interact to Control Neuronal FiringBean, Bruce et al. | 2019
- 10a
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The KdpFABC Complex: What Happens When a P-Type ATPase Hijacks an Ion ChannelStock, Charlott / Hielkema, Lisa / Tascon, Igor / Wunnicke, Dorith / Oostergetel, Gert / Haenelt, Inga / Paulino, Cristina et al. | 2019
- 12a
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The Proton/Electron Coupling Mechanism of Cytochrome C OxidaseRich, Peter R. / Sharma, Vivek et al. | 2019
- 13a
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Uncovering the Molecular Basis for the Clinical N642H Mutation in STAT5B Using Atomistic Molecular SimulationsMeneksedag-Erol, Deniz / de Araujo, Elvin D. / Erdogan, Fettah / Seo, Hyuk-Soo / Dhe-Paganon, Sirano / Gunning, Patrick T. / Rauscher, Sarah et al. | 2019
- 14a
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Atomic-Level Characterization of C-Type Inactivation for Voltage-Gated Potassium Channels Shaker and hERGLi, Jing / Hoon Koh, Young / Rohaim, Ahmed / Perozo, Eduardo / Roux, Benoit et al. | 2019
- 16a
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Understanding the Molecular Underpinnings of Collagen-Protein Interactions in Healthy and Pathological StatesHoop, Cody L. / Zhu, Jie / Kemraj, Allysa / Case, David A. / Baum, Jean et al. | 2019
- 17a
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Isotopically Edited Vibrational Spectra and Dynamics for Three-Strand B-Sheet Peptides. DFT Spectral and MD Dynamics SimulationsKeiderling, Timothy A. / Chi, Heng / McElheny, Dan / Scheerer, David / Shahid Islam, Mohammad / Hauser, Karin et al. | 2019
- 19a
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Twisting of a Mechanosensitive Molecular Probe Detects Lipid Order in MembranesLicari, Giuseppe / Tajkhorshid, Emad et al. | 2019
- 20a
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A Link between Peptide Lipidation and Membrane Curvature ModulusSanderson, John M. / Britt, Hannah M. / Mosely, Jackie A. et al. | 2019
- 21a
-
Elucidating Complimentary Base Specificity of Thymine DNA Glycosylase via Potential of Mean Force Molecular Dynamics SimulationsYoluk, Ozge / Drohat, Alexander C. / MacKerell, Alexander D. et al. | 2019
- 23a
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After the Structure Comes the Dynamics: Molecular Modeling of Glutamate Receptors Reveals Long-Range Allosteric Coupling between Ligand Binding Site and Channel GateKurnikova, Maria G. et al. | 2019
- 24a
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The Nucluear Pore Complex as Intrinsic Reporter for Isotropic Expansion MicroscopyBianchini, Paolo / Pesce, Luca / Cozzolino, Marco / Lanzano', Luca / Diaspro, Alberto et al. | 2019
- 25a
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An Inner Activation Gate Controls TMEM16F Phospholipids ScramblingLe, Trieu / Jia, ZhiGuang / Zhang, Yang / Le, Son C. / Chen, Jianhan / Yang, Huanghe et al. | 2019
- 26a
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Folding Mechanism of β-Helical Passenger Domains from a Bacterial AutotransporterHazel, Anthony / Tik Pang, Yui / Gumbart, James C. et al. | 2019
- 27a
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Understanding the Molecular Parameters Determining the Pathological Properties of Amyloid FibrilsKumar, Harish / Udgaonkar, Jayant B. et al. | 2019
- 29a
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Beta-Myosin Heavy Chain Post-Translational Modifications in Failing and Non-Failing Human HeartsParvatiyar, Michelle S. / Singh, Rakesh K. / Brundage, Elizabeth A. / Whitson, Bryan A. / Janssen, Paul M.L. / Biesiadecki, Brandon J. / Pinto, J. Renato et al. | 2019
- 30a
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Oligomerization of Micropeptides that Regulate SERCASingh, Deo R. / Cho, Ellen / Dalton, Michael / Pribadi, Marsha / Makarewich, Catherine A. / Olson, Eric N. / Robia, Seth L. et al. | 2019
- 31a
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Blood Flow Control by ATP-Sensitive Potassium Channel in HeartZhao, Guiling / Joca, Humberto C. / Lederer, W. Jonathan et al. | 2019
- 32a
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Nurturing Nature for NanotechnologyZwolak, Michael et al. | 2019
- 33a
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Revealing the Dynamics of Single-Molecule Reactions in a Single-Molecule NanoreactorQiu, Kaipei / Yuan, Bo / Long, Yi-Tao et al. | 2019
- 34a
-
Phase Separation of TPX2 Enhances and Spatially Biases Microtubule NucleationPetry, Sabine et al. | 2019
- 35a
-
Measuring Dynamics of the Acid-Sensing Ion Channel N-Terminus using Transition Metal Ion FRETCullinan, Megan / Aryal, Prafulla / Bankston, John et al. | 2019
- 36a
-
Probing Structural States of a Pentameric Ligand-Gated Ion Channel with Small Angle Neutron ScatteringLycksell, Marie / Johansen, Nicolai T. / Howard, Rebecca J. / Arleth, Lise / Lindahl, Erik et al. | 2019
- 38a
-
FRET-Filtered Spectroscopy to Simultaneously Probe Local and Global Conformations of Nucleic AcidsWidom, Julia R. et al. | 2019
- 39a
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Chromatin Remodeling Induced by the Invasion of Yeast Pioneer Transcription Factor Rap1 Revealed by Single-Molecule FRETCao, Anne-Marinette / Mivelaz, Maxime / Boichenko, Iuliia / Bryan, Louise / Kubik, Slawomir / Shore, David / Fierz, Beat et al. | 2019
- 40a
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Recruitment of Actin-Binding Proteins on the Membrane Interface: Effects of Cholesterol on Protein/PIP2 InteractionsFatunmbi, Ololade / Bradley, Ryan / Bucki, Robert / Janmey, Paul / Radhakrishnan, Ravi et al. | 2019
- 41a
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Molecular Dynamics Simulation and Photo-Crosslinking Reveal a Specific Cholesterol Binding Site for the Metabotropic Glutamate Receptor 2Kurth, Markus / Beck, Rainer / Aponte-Santamaria, Camilo A. / Bruegger, Britta et al. | 2019
- 42a
-
Detecting RyR Clusters with CaCLEAN: Validation and Influence of Spatial HeterogeneityLadd, David / Tilunaite, Agne / Roderick, H. Llewelyn / Soeller, Christian / Crampin, Edmund / Rajagopal, Vijay et al. | 2019
- 43a
-
Filopodia Dynamics are Affected by Cation Flux through TRP ChannelsHeckman, Carol A. / Cayer, Marilyn L. / Ademuwiya, Omolade M. et al. | 2019
- 44a
-
Comparison of the Effects of Daptomycin on Bacterial and Model MembranesLee, Ming-Tao / Yang, Pei-Yin / Charron, Nicholas E. / Hsieh, Meng-Hsuan / Chang, Yu-Yung / Hung, Wei-Chin / Huang, Huey W. et al. | 2019
- 46a
-
Atomic Simulations of Trp-Cage Folding by Umbrella Sampling using Q Function as Reaction CoordinateMeshkin, Hamed / Zhu, Fangqiang et al. | 2019
- 48a
-
Investigating How Protein Mixtures Interact with Gold NanoparticlesHill, Rebecca A. / Boulet, Katarina J. / Perera, Randika / Davidson, Mack B. / Fitzkee, Nicholas C. et al. | 2019
- 49a
-
Investigating the Function of Mutl Conformational Changes in Mismatch Repair using smFRETLeBlanc, Sharonda J. / Hao, Pengyu / Hinds, Malikiya A. / Morgan, Andi N. / Gbozah, Korene / Weninger, Keith R. / Erie, Dorothy A. et al. | 2019
- 51a
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Application of Electron Paramagnetic Resonance Spectroscopy to Probe the Structural Topology, Dynamics and Conformational Changes of S21 Pinholin ProteinAhammad, Tanbir / Drew, Daniel L. / Rafferty, Sophia / Sahu, Indra D. / McMarrick, Robert / Lorigan, Gary A. et al. | 2019
- 52a
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Dimerization of Human Adenosine A2AReceptor - Impact of the C-TerminusNguyen, Khanh D. / Seppala, Susanna / Vigers, Michael / Schonenbach, Nicole S. / Han, Songi / O'Malley, Michelle A. et al. | 2019
- 53a
-
Elucidating Olfactory Receptor - Odorant Interactions: Leveraging Drug-Design IdeationsCrasto, Chiquito J. / Lokubandara, Anuththara / Mandla, Vasanth / Buzatu, Dan et al. | 2019
- 54a
-
Site-Directed Labeling of Type II Cannabinoid Receptor CB2 for Structural EPR AnalysisHooper, Levi T. et al. | 2019
- 55a
-
Coarse-Grained Simulations of Transmembrane Domain Interactions in Semaphroin-Plexin-Neuropilin Signal SystemMeng, Zhiyuan / Li, Zhenlu / Buck, Matthias et al. | 2019
- 58a
-
Redefining the Protein Kinase Conformational Space with Machine LearningMan-Un Ung, Peter / Rahman, Rayees / Schlessinger, Avner et al. | 2019
- 59a
-
Experimental Characterization of "Metamorphic" Proteins Predicted from an Ensemble-Based Thermodynamic DescriptionWrabl, James O. / Russo, Miranda / Hoffmann, Jordan / Sheetz, Keila / Munoz, Andrew / Hilser, Vincent J. et al. | 2019
- 61a
-
The Mechanism of Action for Drugs that Undermine HIV-1 Viral Capsid Formation and Activity: Insights from Large-Scale Coarse-Grained SimulationsPak, Alexander J. / Grime, John M.A. / Voth, Gregory A. et al. | 2019
- 62a
-
Probing and Differentiating the Shell and Enzyme Proteins of the Bacterial Microcompartment by Thermal Shift AssayKalim Bari, Naimat / Kumar, Gaurav / Kaur, Simerpreet / Sinha, Sharmistha et al. | 2019
- 63a
-
Resolving the Transition States of Human Hemoglobin Assembly through a Combination of Spectroscopic Studies and All-Atom Molecular Dynamics SimulationsSamuel Mohan Dass, Premila P. / Phillips, George N. / Olson, John S. / Case, David A. et al. | 2019
- 64a
-
Study of the Lysine Deprotonation Mechanism in Ubiquitin Conjugating Enzyme Ubc13Elliott, Katherine / Seward, N. Cole / Hampton, Heath / Sumner, Isaiah et al. | 2019
- 65a
-
A Kinetic Study of Ligand Binding and Conformational Changes in Inducible Nitric Oxide SynthaseNienhaus, Karin / Horn, Michael / Nienhaus, G. Ulrich et al. | 2019
- 66a
-
Structural and Dynamical Effects of Ubiquitination of Key Lysine Residues in the Human Myeloperoxidase. Understanding the Signaling Mechanisms Involved in Autoimmune Responses in Systemic Lupus ErythematosusCarrillo-Vázquez, Daniel / Gómez-Martín, Diana / Jardón-Valadez, Eduardo et al. | 2019
- 67a
-
Light-Induced Activation of Organo-Metallic Co-C Bond in MeCbl-Dependent Methionine Synthase- QM/MM StudyGhosh, Arghya P. / Al Mamun, Abdullah / Kozlowski, Pawel M. et al. | 2019
- 68a
-
Sequence-Dependent Asymmetric Unwrapping of Nucleosomes of YeastKono, Hidetoshi / Luo, Di / Kato, Daiki / Nogami, Jumpei / Ohkawa, Yasuyuki / Kurumizaka, Hitoshi et al. | 2019
- 71a
-
A Platform for Investigating Nuclear Organization and its Changes During Human iPSC DifferentiationRafelski, Susanne M. et al. | 2019
- 72a
-
Chromatin Folding Heterogeneity Inferred from High-Resolution Nucleosome StructuresTodolli, Stefjord / Yager, John / Olson, Wilma K. et al. | 2019
- 73a
-
DNA Mismatch Repair Relies Entirely on Stochastic TransactionsLiu, Jiaquan / Lee, Ryang-Geun / Britton, Brooke / London, James / Hanne, Jeungphill / Lee, Jong-Bong / Fishel, Richard et al. | 2019
- 75a
-
Single-Molecule Studies Reveal New Replication Reactivation Pathways of Bacteriophage T7Sun, Bo / Wang, Michelle D. et al. | 2019
- 76a
-
Tracking the Acceleration of DNA Repair in X-Ray Irradiated Cells by Interaction with Healthy CellsJin, Sha / Cordes, Nils et al. | 2019
- 78a
-
The Role of Ergosterol in Phase Separation of Yeast Vacuole MembranesLeveille, Chantelle L. / Cornell, Caitlin E. / Merz, Alexey J. / Keller, Sarah L. et al. | 2019
- 79a
-
Investigating Single-Cell Variation in Membrane Fluidity and Respiration RatesOjha, Krishna / Blechman, Sam / Kasburg, Joshua / Konopka, Michael C. et al. | 2019
- 80a
-
Nesting Lipid Bilayers in Nanopores: Effect of Pore Diameter on Macroscopic Order and the Layer CountJafarabadi, Morteza / Chestnut, Melanie / Marek, Antonin / Nevzorov, Alexander / Smirnov, Alex I. et al. | 2019
- 81a
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Excitation of Fluorescent Lipid Probes Accelerates Phospholipid Vesicle Rupture and Supported Lipid Bilayer FormationBaxter, Ashley M. / Wittenberg, Nathan J. et al. | 2019
- 83a
-
Membrane Remodeling Induced by a pH Dependant Pore Forming Peptide via Atomic Force MicroscopyPittman, Anna / Kim, Sarah Y. / Wimley, William C. / Hristova, Kalina / King, Gavin et al. | 2019
- 84a
-
Effect of Biopolymer Tethers on Antimicrobial Peptide Activity in BiomembranesDoole, Fathima T. / Singharoy, Abhishek / Brown, Michael F. / Kim, Minkyu et al. | 2019
- 86a
-
The Role of Greasy Residues in Teixobactin DerivativesWen, Po-Chao / Tajkhorshid, Emad / Rempe, Susan B. et al. | 2019
- 87a
-
Effect of Alcohol on Water Translocation in All-Atom Simulations of Osmotic Gradient Across Lipid MembranesCoffman, Robert E. / Busath, David D. / Woodbury, Dixon J. et al. | 2019
- 88a
-
Influence of Sterol in Ternary Mixtures Containing Sphingomyelin: An All-Atom Molecular Dynamics StudyFavela-Rosales, Fernando / Galván-Hernández, Arturo / Hernández-Cobos, Jorge / Ortega-Blake, Iván et al. | 2019
- 90a
-
Distinct Interactions of Sodium and Calcium Cations and Neutral Phospholipid Membranes and How to Simulate ThemMartinez-Seara, Hector / Javanainen, Matti / Melcrová, Adéla / Jurkiewicz, Piotr / Jungwirth, Pavel / Magarkar, Aniket / Hof, Martin / Melcr, Josef / Nencini, Ricky / Ollila, Samuli O. et al. | 2019
- 91a
-
Curvature Generation by Endocytic Clathrin CoatsFerguson, Joshua / Cakez, Cemal / Hasan, Farah / Cocucci, Emanuele / Kural, Comert et al. | 2019
- 92a
-
Mechanochemical Feedback Control of Dynamin Independent Endocytosis Modulates Membrane Tension in Adherent CellsJose Thottacherry, Joseph / Joanna Kosmalska, Anita / Pradhan, Susav / Pal Singh, Parvinder / Trepat, Xavier / Vishwakarma, Ram / Pullarkat, Pramod / Roca-Cusachs, Pere / Mayor, Satyajit et al. | 2019
- 94a
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Quantitative In Silico Analysis of the Arrhythmogenic CaMKII-Sodium-Calcium-CaMKII Feedback in the Failing Rabbit Ventricular MyocyteLiu, Caroline / Hegyi, Bence / Ni, Haibo / Bers, Donald M. / Grandi, Eleonora / Morotti, Stefano et al. | 2019
- 95a
-
An Autosomal Dominant Mutation in Calsequestrin 2 Causes CPVT Without Changing Protein LevelsWleklinski, Matthew / Parikh, Shan / Knollmann, Bjorn C. et al. | 2019
- 96a
-
Double Regulation of Cardiac Excitation-Contraction Coupling and Oxidant Stress by PirfenidoneMonsalvo-Villegas, Adrian / Avila, Guillermo et al. | 2019
- 97a
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Pharmacological and Ischemic Preconditioning Up-Regulate the Expression of Socs in Adult Cardiac Myocytes: Its Physiological SignificanceSampieri, Raúl / Thomas, Joice / Garcia, Maria C. / Carrillo, Elba D. / Fuentes, Eridani / Orea, Wilibaldo / Sanchez, Jorge A. et al. | 2019
- 98a
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The Effects of Pinacidil, an ATP Sensitive K+ Channel Opener on Cardiac Na+/Ca2+ Exchanger Function in Guinea Pig CardiomyocytesIguchi, Keisuke / Saotome, Masao / Yamashita, Kanna / Ikoma, Takenori / Hasan, Prottoy / Maekawa, Yuichiro / Watanabe, Yasuhide et al. | 2019
- 99a
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Effect of a Small Molecule Activator of Potassium Currents on Repolarization Reserve in hiPSC-CardiomyocytesTreat, Jacqueline A. / Goodrow, Robert J. / Aistrup, Gary L. / Bot, Corina T. / Cordeiro, Jonathan M. et al. | 2019
- 100a
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Longitudinal Cardiotoxic Effect of Doxorubicin in a Multicellular Cardiac ModelZlochiver, Viviana / Edwards, Stacie / Joshi-Mukherjee, Rosy et al. | 2019
- 101a
-
Screening of Negative Charges by Ca2+ in the Turret Region Controls Kv7.1 Inactivation Gating and is Regulated by PIP2 and CalmodulinAttali, Bernard / Tobelaim, William S. / Lipinsky, Maya / Peretz, Asher S. / Yakubovich, Daniel / Paas, Yoav et al. | 2019
- 102a
-
Nature Utilization of the Slow Inactivation Mechanism in Voltage Gated K+ ChannelsKarbat, Izhar / Gueta, Hagit / Szanto, Tibor / Hamer-Rogotner, Shelly / Dym, Orly / Frolow, Felix / Gordon, Dalia / Panyi, Gyorgy / Gurevitz, Michael / Reuveny, Eitan et al. | 2019
- 103a
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Quantum Calculations on the K+ Ion in the KV1.2 Channel Pore: Hydration and CosolvationKariev, Alisher M. / Green, Michael E. et al. | 2019
- 104a
-
Differential Regulation of BK Channels by Fragile X Mental Retardation ProteinKshatri, Aravind / Cerrada, Alejandro / Gimeno, Roger / Giraldez, Teresa et al. | 2019
- 105a
-
Study of a Heteromeric Kainate Receptor Gluk2/K5 by Probing Single-Molecule FRETPaudyal, Nabina / Litwin, Douglas B. / Berka, Vladmir / Carrillo Flores, Elisa / Jayaraman, Vasanthi et al. | 2019
- 106a
-
Computational Characterization of the Binding of Non-Competitive Inhibitors to AMPA ReceptorsNarangoda, Chamali / Sakipov, Serzhan / Kurnikova, Maria G. et al. | 2019
- 107a
-
Development of a High-Throughput Ca2+ Flux Screening Assay to Monitor Cyclic Nucleotide-Gated Channel Activity and Evaluate Achromatopsia Disease Mutant Channel FunctionTanaka, Jacqueline / Almonte, Cristy / McDuffie, Elizabeth / Jones, Laura / Colussi, Dennis / Jacobson, Marlene et al. | 2019
- 108a
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Nucleotide Modulation of KATP Channels Disentangled with FRETPuljung, Michael C. / Usher, Samuel / Vedovato, Natascia / Ashcroft, Frances et al. | 2019
- 109a
-
Elucidating the Function and Cell-Specific Interactions of P2X7 Receptor Variants Linked to Mental DisordersHomann Poulsen, Mette / Fang, Jamie / Pless, Stephan A. et al. | 2019
- 111a
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Treatment of CaV1.2 Channelopathies May Be Complicated by Altered Channel InactivationBamgboye, Moradeke A. / Traficante, Maria / Yue, David T. / Dick, Ivy E. et al. | 2019
- 112a
-
Skeletal γ1 Subunit Modulation of Human CaV1.1 and CaV1.2 ChannelsAngelini, Marina / Savalli, Nicoletta / Yusifov, Taleh / Olcese, Riccardo et al. | 2019
- 113a
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Pore-Blocking Effect of Isoindoline MDIMP on Voltage-Gated Calcium ChannelsDe La Rosa, Juan Antonio M. / García-Castañeda, Maricela / Nishigaki, Takuya / Carlos Gomora, Juan / Mancilla-Percino, Teresa / Avila, Guillermo et al. | 2019
- 115a
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Engineered Thin Filament Mutation to Increase Calcium Sensitivity of Force in Tropomyosin Mutation of Dilated CardiomyopathyKooiker, Kristina B. / Powers, Joseph D. / Tardiff, Jil / Regnier, Michael / Davis, Jennifer / Moussavi-Harami, Farid et al. | 2019
- 116a
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C0 Ig-Domain of Cardiac Myosin Binding Protein-C Interacts with the Regulatory Light Chain of Myosin-S1 Bound to the Native Cardiac Thin FilamentRisi, Cristina / Belknap, Betty / Harris, Samantha / White, Howard / Galkin, Vitold E. et al. | 2019
- 117a
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Single Molecule Visualization of Cardiac Myosin-Binding Protein C N-Terminal Fragments Interacting with Regulated Actin Filaments: Mechanisms of Calcium SensitizationInchingolo, Alessio V. / Previs, Samantha B. / Previs, Michael J. / Warshaw, David M. / Kad, Neil M. et al. | 2019
- 118a
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Impact of Hypertrophic Cardiomyopathy Mutations on the Cardiac Myosin Super-Relaxed StateByrapuneni, Sriya / Chu, Sami / Muretta, Joseph M. / Thomas, David D. et al. | 2019
- 119a
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Mapping the Biochemical Interactions of the Mechanoresponsive Contractility ControllerKothari, Priyanka / Srivastava, Vasudha / Aggarwal, Vasudha / Tchernyshyov, Irina / Van Eyk, Jennifer / Ha, Taekjip / Robinson, Douglas N. et al. | 2019
- 120a
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Large Scale Simulations of Cell Resolved Tissue by a Cellular Potts ModelRosenbauer, Jakob et al. | 2019
- 122a
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Scutoids: Understanding the 3D Packing of Curved EpitheliaBuceta, Javier / Pedro, Gómez-Gálvez / Vicente-Munuera, Pablo / Escudero, Luis M. et al. | 2019
- 123a
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High Troughput Microfluidic Characterization of Erythrocyte Shapes and Mechanical VariabilityReichel, Felix / Mauer, Johannes / Ahsan Nawaz, Ahmad / Gompper, Gerhard / Guck, Jochen R. / Fedosov, Dmitry et al. | 2019
- 124a
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Kinesin-1 Acts Independently and Also Regulates Kinesin-3-Dependent Transport of Synaptophysin Vesicles in Mammalian AxonsEncalada, Sandra E. et al. | 2019
- 126a
-
Mechanistic Study of a Peptidase Containing ABC-Transporter, Employing Microsecond Level Molecular Dynamics Simulations and Enhanced Sampling TechniquesOgden, Dylan S. / Govind Kumar, Vivek / Moradi, Mahmoud et al. | 2019
- 127a
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What is Your Machine Really Doing? Systematic Exploration of Alternative Mechanisms as Applied to TransportGeorge, August / Grabe, Michael / Rosenberg, John M. / Zuckerman, Daniel M. et al. | 2019
- 128a
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Single-Molecule Studies of ATP Binding to the Sodium PumpMadhira, Sushi / Lamb, Don C. / Pratap, Promod R. et al. | 2019
- 129a
-
Predicting TGF-β-Induced Epithelial-Mesenchymal Transition using Data AssimilationMendez, Mario J. / Hoffman, Matthew J. / Cherry, Elizabeth M. / Lemmon, Christopher A. / Weinberg, Seth H. et al. | 2019
- 130a
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Prediction of Metabolite Concentrations, Rate Constants and Post-Translational Regulation of Neurospora Crassa using Maximum Entropy Optimizations and Reinforcement LearningCannon, William R. / Britton, Samuel R. / Banwarth-Kuhn, Mikahl / Alber, Mark / Hurley, Jennifer M. / Jankowski, Meaghan S. / Zucker, Jeremy D. / Baxter, Douglas J. / Kumar, Neeraj / Baker, Scott E. et al. | 2019
- 132a
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Quantifying FRET Efficiency between Fluorescent Proteins using Fluorescence Polarization MicroscopyRao, Vishnu et al. | 2019
- 134a
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Molecular Counting by Photon Statistics in Confocal Fluorescence ImagingKoenig, Marcelle / Berlage, Caroline / Reisch, Paja / Oelsner, Christian / Koberling, Felix / Ta, Haisen / Erdmann, Rainer et al. | 2019
- 135a
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Brownian Motion using a Piezo Actuated Microscope StageVickers, Nicholas A. / Andersson, Sean B. et al. | 2019
- 136a
-
Human Stem Cell Structures Measured with Concentration-Calibrated Super-Resolution MicroscopyThirstrup, Derek / Wiegraebe, Winfried et al. | 2019
- 138a
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Three-Color Single-Molecule FRET and Fluorescence Lifetime Analysis of Fast Protein FoldingYoo, Janghyun / Louis, John M. / Gopich, Irina V. / Sung Chung, Hoi et al. | 2019
- 139a
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High-Precision FRET Reveals Sequence Dependent Structures of RNA Three-Way JunctionsDoroshenko, Olga / Vardanyan, Hayk / Prakash, Aiswaria / Froebel, Sascha / Kalinin, Stanislav / Sindbert, Simon / Opanasyuk, Oleg / Hanke, Christian A. / Mueller, Sabine / Gohlke, Holger et al. | 2019
- 140a
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MDFF Error Analysis: A Tool for Determining Stereochemical and Thermodynamic Correct StructuresSarkar, Daipayan / Vant, John / Shekhar, Mrinal / Richardson, Jane S. / Skeel, Robert / Singharoy, Abhishek et al. | 2019
- 142a
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Gromaps: A Gromacs-Based Toolset to Analyse Density Maps Derived from Molecular Dynamics SimulationsBriones, Rodolfo / Blau, Christian / Kutzner, Carsten / de Groot, Bert L. / Aponte-Santamaría, Camilo et al. | 2019
- 143a
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Hamiltonian Replica Exchange for Enhanced Sampling of the Conformational Landscape for Intrinsically Disordered ProteinsKim, Justin S.H. / Rauscher, Sarah et al. | 2019
- 146a
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Luminescent Molecular Sensors for the Selective Detection of Neurodegenerative Disease Protein Pathology in CSFMonge, Florencia / Fanni, Adeline / Jiang, Shanya / Whitten, David G. / Bhaskar, Kiran / Chi, Eva Y. et al. | 2019
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Optimizing Nucleic Acid Biomarker Detection in a Solid-State Nanopore Through Probabilistic ModelingBearden, Samuel / Zahid, Osama K. / Hall, Adam R. et al. | 2019
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Mechanical Strength of Catch Bond Forming FimH and MannoseCarlucci, Laura A. / Johnson, Keith / Thomas, Wendy E. et al. | 2019
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L-Type Calcium Channels are a Major Source of Plasmalemmel Calcium Influx for Drosophila CardiomyocytesLimpitikul, Worawan B. / Viswanathan, Meera C. / O'Rourke, Brian / Yue, David T. / Cammarato, Anthony et al. | 2019
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Structural Insights into Recognition of Ryanodine Receptors by PKAHaji-Ghassemi, Omid / Yuchi, Zhiguang / Van Petegem, Filip et al. | 2019
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Molecular Link between MCU and MRS2P Channels for Mitochondrial Ion Homeostasis and Energy MetabolismSanthanam, Shanmughapriya / Zhang, Xueqian / Song, Jianliang / Cheung, Joseph Y. / Basile Stathopulos, Peter / Madesh, Muniswamy et al. | 2019
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Direct Observation of Individual Tubulin Dimers Binding to Growing MicrotubulesMickolajczyk, Keith J. / Geyer, Elisabeth / Kim, Tae / Rice, Luke / Hancock, William O. et al. | 2019
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Tau's Proline Rich Region Dominates Tubulin BindingMcKibben, Kristen / Rhoades, Elizabeth et al. | 2019
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Direct Observation of Protein Translocation by the 26S ProteasomeJonsson, Erik / Bard, Jared / López-Alfonzo, Erika M. / Goodall, Ellen / Dong, Ken / Martin, Andreas et al. | 2019
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Atomic Structure of Nearly Indestructible Pili from a Hyperthermophilic AcidophileWang, Fengbin / Cvirkaite-Krupovic, Virginija / Wall, Joe S. / Prangishvili, David / Krupovic, Mart / Egelman, Edward H. et al. | 2019
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Intracellular Metal Speciation in Streptococcus sanguinis is Pivotal for Redox MaintenanceMurgas, Cody / Forney, Ashley K. / Baker, Shannon / An, Seon-Sook / Kitten, Todd O. / Lucas, Heather R. et al. | 2019
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E. Coli Adenylate Kinase Exhibits Inter-Domain CouplingRehfus, Joseph E. / Hilser, Vincent J. et al. | 2019
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Markov State Model of Influenza Hemagglutinin Reveals Structural Basis for Group 1 Influenza Inhibition by ArbidolKochanek, Sarah E. / Amaro, Rommie E. et al. | 2019
- 164a
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Phase Partitioning of Peptide Anchors in Plasma Membrane Vesicles Predicts Their Recruitment to B Cell Receptor Clusters in Live CellsShelby, Sarah A. / Serrano, Ivan C. / Levental, Kandice R. / Levental, Ilya / Veatch, Sarah L. et al. | 2019
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Structural Topology of Glycoprotein Surface Networks using High Throughput Atomistic Modeling and Graph TheoryChakraborty, Srirupa / Berndsen, Zachary / Lopez, Cesar / Ward, Andrew / Korber, Bette / Hengartner, Nicolas / Gnanakaran, S. et al. | 2019
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A New Step to Elucidate Molecular Mechanisms Involved in Caries Formation: NMR Characterization of the C3 Domain from Streptococcus Mutans Adhesin P1Riviere, Gwladys / Long, Joanna / Brady, Jeanine et al. | 2019
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A Multidrug and Toxin Efflux (MATE) Transporter Involved in Aluminum Resistance is Modulated by a CBL5/CIPK2 Calcium Sensor/Protein Kinase ComplexMiller, Julia / Coluccio, Alison / Niklas Offenborn, Jan / Mähs, Anette / Kudla, Jörg / Kochian, Leon / Piñeros, Miguel et al. | 2019
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Mechanisms, Diversity and Optogenetic Applications of Channelrhodopsins from Cryptophyte AlgaeGovorunova, Elena G. / Spudich, John L. et al. | 2019
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Generating Potent and Selective Inhibitors of Kv1.3 Ion Channel by Fusing Knottins (Venom Derived Mini Proteins) into Peripheral CDR Loops of AntibodiesKaratt-Vellatt, Aneesh / Bell, Damian C. / Surade, Sachin B. / Luetkens, Tim / Masters, Ed W. / Luther, Alice M. / Sørensen, Naja Møller M. / Butt, Neil J. / McCafferty, John et al. | 2019
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Single Particle Trajectories Reveal Active Endoplasmic Reticulum Luminal FlowParutto, Pierre / Chambers, Joseph E. / Fantham, Marcus / Young, Laurence / Marciniak, Stefan / Kaminski, Clemens F. / Ron, David / Holcman, David / Avezov, Edward et al. | 2019
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Molecular Counting with DNA Origami - Verification and Validation Towards Biological ApplicationsNino, Daniel F. / Djarkarsana, Daniel / Zilman, Anton / Milstein, Joshua et al. | 2019
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Thin Filament Regulation Blends Thermodynamic and Mechanical MechanismsZot, Henry G. / Chase, P. Bryant / Hasbun, Javier E. / Pinto, J. Renato et al. | 2019
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Evolution of the Intrinsically Disordered Activation Domain in a Hox Transcription FactorLiu, Ying / Huang, Annie / Booth, Rebecca / Mendes, Gabriela / Merchant, Zabeena / Matthews, Kathleen S. / Bondos, Sarah E. et al. | 2019
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The Disordered Protein Bugz Conserves Mitotic Function and Liquid-Liquid Phase Separation across 1.6 Billion Years of EvolutionChin, Alexander F. / Hilser, Vincent J. / Zheng, Yixian et al. | 2019
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Simulation Guided Design of Spectroscopy Experiments via Maximizing Kinetic Information GainMittal, Shriyaa / Shukla, Diwakar et al. | 2019
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Disassembling and Reassembling Complex Structure of Glutamate Dehydrogenase 1 (DGH-1), Monitored by Tryptophan and 1-Anilinonaphthalene-8-Sulfonate (ANS) FluorimetryZelent, Bogumil / Wilson, David F. / Matschinsky, Franz M. et al. | 2019
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Investigating the Response of Type IV Pilins and Type IV Pilus Filaments to Applied Force using All-Atom Steered Molecular Dynamics SimulationsFairfield, Maria N. / Jones, Stephen J. / Biais, Nicolas / Baker, Joseph L. et al. | 2019
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Single-Molecule Force Spectroscopy of M-Value Mutants of Staphylococcal Nuclease Indicates Complex Protein Folding LandscapeRives, James / Rehfus, Joseph / Hilser, Vincent J. et al. | 2019
- 187a
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Cryo-EM Structural Analysis of Neuronal Nitric Oxide SynthasePospiech, Thomas H. / Morishima, Yoshihiro / Osawa, Yoichi / Southworth, Daniel R. et al. | 2019
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Effects of Local and Global Dynamics on the Supertertiary Organization of Postsynaptic Density Protein 95Hamilton, George L. / Kubiak, Jakub / Seidel, Claus A.M. / Sanabria, Hugo et al. | 2019
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Monitoring Dynamics of Protein Nascent Chain on the Ribosome using PET-FCSLiutkute, Marija / Samatova, Ekaterina / Maiti, Manisankar / Holtkamp, Wolf H. / Enderlein, Jörg / Rodnina, Marina V. et al. | 2019
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A Comprehensive Investigation of the Stabilization of Monomeric Hfgf1 by Heparin Hexasaccharide using Microsecond-Level MD Simulations and Enhanced Sampling TechniquesGovind Kumar, Vivek / Agrawal, Shilpi / Kumar, T.K.S. / Moradi, Mahmoud et al. | 2019
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Structural Dynamics of c-Myb DNA-Binding Domain Revealed by DXT and Thermal AnalysisInaba, Satomi / Hosoe, Yuhi / Sasaki, Yuji C. / Sekiguchi, Hiroshi / Oda, Masayuki et al. | 2019
- 192a
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Biophysical Characterization of Differences in Domain-Domain Interactions between the Apolipoprotein E4 and E3Dolai, Subhrajyoti / Garai, Kanchan et al. | 2019
- 193a
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Towards Understanding Amyloid Formation Mechanism of Beta2-Microglobulin Induced by Copper IonsLiang, Chungwen et al. | 2019
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Modeling the Assembly Order of Multimeric Heteroprotein ComplexesPeterson, Lenna / Togawa, Yoichiro / Esquivel-Rodriguez, Juan / Terashi, Genki / Christoffer, Charles / Roy, Amitava / Shin, Woong-Hee / Kihara, Daisuke et al. | 2019
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Mechanisms of Protein Fibril Formation in Amyloid Beta and Lysozyme ProteinsPerez, Carlos M. / Ullah, Ghanim / Miti, Tatiana / Muschol, Martin et al. | 2019
- 197a
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Polymer Theory for Sequence-Specific Phase Separation Behaviors of Charged Intrinsically Disordered ProteinsLin, Yi-Hsuan / Forman-Kay, Julie D. / Sun Chan, Hue et al. | 2019
- 198a
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Coarse-Grained Simulations of Disordered Proteins: Effect of Interaction Potentials and Charge Pattern ParametersDas, Suman et al. | 2019
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Protein Unfolded States are Characterized by the Duality of Sequence-Specific Conformational Preferences and Ensemble-Averaged Features of Canonical Random CoilsHolehouse, Alex S. / Peran, Ivan / Stenzoski, Natalie E. / Zou, Junjie / Piserchio, Andrea / Ghose, Ranajeet / Carrico, Isaac S. / Bilsel, Osman / Raleigh, Daniel P. / Pappu, Rohit V. et al. | 2019
- 200a
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Characteristics of the Binding Interaction between Pdx1 and SPOPUsher, Grace A. / Rohac, Roman / Boal, Amie K. / Showalter, Scott A. et al. | 2019
- 201a
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Exploring the Structural Properties of Synaptotagmin's Intrinsically Disordered RegionFealey, Michael E. / Hinderliter, Anne / Thomas, David D. et al. | 2019
- 203a
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Binding from Both Sides: TolR and Full-Length OmpA Bind and Maintain the Local Structure of the E. Coli Cell WallBoags, Alister T. et al. | 2019
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Exploring the Interhelical Landscape of the β-2 Adrenergic Receptor to Identify Druggable Intermediate States using Enhanced-Sampling Molecular Dynamics and Site Identification by Ligand Competitive Saturation (SILCS)Lind, Christoffer / Deshpande, Deepak / MacKerell, Alexander D. et al. | 2019
- 206a
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Dynamic Actin Mediated Nanoclustering of Cd44 Regulates its Meso-Scale Organization at the Plasma MembraneSil, Parijat / Nath, Sangeeta / Mateos, Nicolas / Fujiwara, Takahiro / Garcia-Parajo, Maria F. / Kusumi, Akihiro / Mayor, Satyajit et al. | 2019
- 207a
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Electromigration of Cell Surface Macromolecules during GalvanotaxisSarkar, Anyesha / Kobylkevich, Brian M. / Graham, David M. / Messerli, Mark A. et al. | 2019
- 208a
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Nuclear Myosin VI Stabilizes RNA Polymerase II in Transcription FactoriesHari Gupta, Yukti / Fili, Natalia / dos Santos, Alia / Chew, Teng-Leong / Aaron, Jesse / Wang, Lin / Toseland, Christopher P. et al. | 2019
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Tfiih Generates a Six-Base-Pair Open Complex during Eukaryotic Transcription InitiationGalburt, Eric A. / Tomko, Eric J. / Fishburn, James / Hahn, Steven et al. | 2019
- 211a
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TIN2 is an Architectural Protein Stabilizing TRF1 at TelomerePan, Hai / Dangi, Saroj / Kaur, Parminder / Hao, Pengyu / Weninger, Keith / Riehn, Robert / Opresko, Patricia / Wang, Hong et al. | 2019
- 212a
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Investigating the Effect of Various FMRP Isoforms on microRNA BiogenesisImperatore, Joshua A. / Roth, John / Rita Mihailescu, Mihaela et al. | 2019
- 213a
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Characterizing the Binding of the HIV-1 NC Protein to Hairpins Formed by CAG RepeatsDillon, Melanie / Ndambakuwa, Yustinah / Ehirim, Henrietta / Volle, Catherine B. et al. | 2019
- 215a
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Dynamic Effects of Calcium on Membranes Containing PhosphatidylserineValentine, Mason L. / Cardenas, Alfredo E. / Elber, Ron / Baiz, Carlos R. et al. | 2019
- 216a
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Emergent Shape Sensing of Dynamic MembranesCamley, Brian A. et al. | 2019
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-
Pathways and Molecular Mechanisms of Microdomain-Dependent Membrane TraffickingDiaz-Rohrer, Barbara / Lorent, Joseph / Castello-Serrano, Ivan / Levental, Kandice / Levental, Ilya et al. | 2019
- 221a
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Ion Transport Through Large-Diameter DNA Origami Nanotube Channels Across Synthetic MembranesDhanasekar, Naresh N. / Schulman, Rebecca B. et al. | 2019
- 222a
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Determining the Mechanism of SMase-Mediated Inhibition of CFTR Current in Primary Bronchial Epithelial CellsCottrill, Kirsten A. / Stauffer, Brandon B. / McCarty, Nael A. et al. | 2019
- 225a
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PH-Tunable Floating Lipid BilayersMichalak, Dennis J. / Lösche, Mathias / Hoogerheide, David et al. | 2019
- 229a
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Mechanism for cAMP Overshoot in Ventricular Myocytes Following β1-Adrenergic StimulationMeyer, Emily E. / Lewis, Timothy J. / Clancy, Colleen E. et al. | 2019
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Effects of Varying Transverse and Axial Tubules in a Three-Dimensional Model of Calcium Signaling in the Human Atrial MyocyteZhang, Xianwei / Ni, Haibo / Morotti, Stefano / Sato, Daisuke / Grandi, Eleonora et al. | 2019
- 235a
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Biphasic Ca2+ Regulation of SK Channels in Ventricular Cardiomyocytes Maximizes Their Conductance during a Late Phase of the Action PotentialBronk, Peter / Polina, Iuliia / Terentyeva, Radmila / Hamilton, Shanna / Terentyev, Dmitry et al. | 2019
- 236a
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Role of Orai1 and Store Operated Calcium Entry (SOCE) in Liver: Effects on Hormone-Induced Calcium Signaling and Glucose MetabolismBird, Gary S. / D'Agostin, Diane / Desai, Pooja / Putney, James W. et al. | 2019
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The Role of S-Acylation in Store Operated Calcium EntryWest, Savannah J. / Wang, Qiaochu / Zhu, Michael X. / Akimzhanov, Askar M. / Boehning, Darren et al. | 2019
- 238a
-
Null-Sarcolipin Equine Muscle Shows Enhanced SERCA Calcium Transport Which May Potentiate the Prevalence of Exertional RhabdomyolysisAutry, Joseph M. / Svensson, Bengt / Karim, Christine B. / Perumbakkam, Sudeep / Chen, Zhenhui / Finno, Carrie J. / Thomas, David D. / Valberg, Stephanie J. et al. | 2019
- 239a
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Pade Approximation of Single-Channel Calcium Nanodomains in the Presence of Cooperative Calcium BuffersChen, Yinbo / Matveev, Victor et al. | 2019
- 240a
-
Functionally Identifying Members of the MscS Superfamily of Ion Channels in Paraburkholderia MembranesDickinson, Hannah M. / Miller, Brittni L. / Malcolm, Hannah R. et al. | 2019
- 241a
-
Partial Characterization of the Inactivation Process of the Human Erythrocyte Mechano-Activated K+ Channel a (HEMKCA): Effect of Membrane Potential, Ca2+ and Rb+Isturiz, Diana / Mata, Alejandro / Romero, Jesus G. et al. | 2019
- 242a
-
Synthesis of Romk1/2 Protein in E.ColiKrajewska, Milena / Koprowski, Piotr / Szewczyk, Adam et al. | 2019
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A Novel Gain of Function Mutation of Piezo-1 is Investigated in Red Blood Cells by High-Throughput Patch ClampBruggemann, Andrea / Rotordam, Giustina M. / Becker, Nadine / Fertig, Niels / Bianchi, Paola / Rapedius, Markus / Kaestner, Lars et al. | 2019
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Allosteric Modulation via Transmembrane Interfaces in a Pentameric Ligand-Gated Ion ChannelHoward, Rebecca J. / Zhuang, Yuxuan / Nakamura, Shinjiro / Lycksell, Marie / Kiik, Helen / Rovšnik, Urška / Bergh, Cathrine / Heusser, Stephanie A. / Orellana, Laura / Lindahl, Erik et al. | 2019
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Modeling Trapping Block of HERG for CiPA: Does the Basal HERG Mode Matter?Franks, Brandon / Nowak, Mark / Panama, Brian / Rasmusson, Randall / Bett, Glenna et al. | 2019
- 247a
-
Voltage- and State-Dependent Blockade of hERG Potassium Channels by FentanylTschirhart, Jared / Li, Wentao / Guo, Jun / Zhang, Shetuan et al. | 2019
- 248a
-
Insights into Selectivity Filter Gating of K2P Channels from Single-Channel RecordingsConrad, Linus J. / Tucker, Stephen J. et al. | 2019
- 249a
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Structural Modeling of Drug Interactions with hERG Channel in Open and Closed StatesEmigh, Aiyana M. / DeMarco, Kevin R. / Furutani, Kazuharu / Sack, Jon T. / Clancy, Colleen E. / Vorobyov, Igor V. / Yarov-Yarovoy, Vladimir et al. | 2019
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The Physical Bases of Forming a Smooth Boundary between an Expanding Arp 2/3 Actin Network and a Contractile Actomyosin NetworkSharma, Medha / Harris, Tony et al. | 2019
- 252a
-
Spatiotemporal Organization of Microtubules in Branched NetworksThawani, Akanksha / Stone, Howard A. / Shaevitz, Joshua W. / Petry, Sabine et al. | 2019
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-
Structure of the Tpm3.1 N-Terminus: A New Target for Anti-Cancer TreatmentGhosh, Anita / Janco, Miro / Böcking, Till / Gunning, Peter W. / Lehman, William / Rynkiewicz, Michael J. et al. | 2019
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Structural Transformation of Microtubules in the Presence of Cationic PolymersLee, Juncheol / Song, Chaeyon / Lee, Jimin / Miller, Herb P. / Wilson, Leslie / Safinya, Cyrus R. / Chul Choi, Myung et al. | 2019
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Structural Studies of CAP-Gly Domain of Dynactin Assembled with Microtubules by Magic Angle Spinning NMR SpectroscopyGuo, Changmiao / Williams, John C. / Polenova, Tatyana et al. | 2019
- 259a
-
Electrostatic Interactions Within Loop 1 and the Force Generation Region of Human Cardiac Myosin Affect the Rate of Actomyosin Dissociation and ADP ReleaseGargey, Akhil / Ge, Jinghua / Grdzelishvili, Alex / Tkachev, Yaroslav / Nesmelov, Yuri E. et al. | 2019
- 261a
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The Mechanistic Role of Tropomyosin Overlap Dysregulation in Early Cardiomyopathic Disease ProgressionLynn, Melissa L. / Holeman, Teryn A. / Tal-Grinspan, Lauren / Deranek, Andrea / Tardiff, Jil C. et al. | 2019
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Annulment of Cardiac Muscle Length-Dependent Force Activation in Transgenic Mice Bearing the HcTnT-I79N MutationLandim Vieira, Maicon / Knollmann, Bjorn / Hwang, Hyun S. / Pinto, J. Renato / Chase, P. Bryant et al. | 2019
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Impact of Human Beta-Cardiac Myosin Mutation Implicated in Both Hypertrophic and Dilated CardiomyopathyTang, Wanjian / Gunther, Laura K. / Cooper, Jonathan / Desetty, Rohini / Yengo, Christopher M. et al. | 2019
- 264a
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Predicting and Preventing Myocardial Remodeling in a Murine Model of Dilated CardiomyopathyPowers, Joseph D. / Flint, Galina / Tardiff, Jil / Regnier, Michael / Moussavi-Harami, Farid / Davis, Jennifer et al. | 2019
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Isometric and Isotonic Twitch Dynamics in Omecamtiv Mercarbil Treated Intact Rat Cardiac TrabeculaSchick, Brianna M. / Matus, Alexandra R. / Chung, Charles S. et al. | 2019
- 266a
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Mitochondrial Metabolic Function is Affected by Inner Membrane MorphologyAfzal, Nasrin / Mannella, Carmen / Lederer, William J. / Jafri, Mohsin S. et al. | 2019
- 267a
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Modeling the Insertion of Hexokinase in the Mitochondrial Outer Membrane and its Complex Formation with VDACHaloi, Nandan / Wen, Po-Chao / Camara, Amadou K.S. / Kwok, Wai-Meng / Tajkhorshid, Emad et al. | 2019
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Mitochondrial Potassium Channels: Regulation by Gaseous TransmitterSzewczyk, Adam / Walewska, Agnieszka / Rotko, Daria / Kulawiak, Bogusz / Koprowski, Piotr et al. | 2019
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Mitochondrial Membrane Potential Oscillations Persist during Reperfusion After Ischemia in MCU Knockout CardiomyocytesAshok, Deepthi / Papanicolaou, Kyriakos / O′Rourke, Brian et al. | 2019
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Mitochondrial Calcium Deregulation in Tau K18-Treated Cortical Neurons and AstrocytesBritti, Elena / Esteras Gallego, Noemi / Ros, Joaquim / Abramov, Andrey Y. et al. | 2019
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Systemic Metabolomics and Mitochondrial Energetics in High- Compared to Low-Running Capacity Rats as a Function of AgeAon, Miguel A. / Lachance, Andrew / Mitchell, Sarah J. / Bullock, Kelsey / Cortassa, Sonia / Sollott, Steven J. et al. | 2019
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St. John's Worth Extract Induces Apoptosis and Inhibits Cancer-Related Inflamation in Basal Cell Carcinoma Cell LinesCelik, Ebru / Celik, M. Salih / Kaplan, H. Mahir / Singirik, Ergin et al. | 2019
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Integration of Reaction-Diffusion Master Equation and Brownian Dynamics Methodologies to Simulate a Minimal CellEarnest, Tyler M. / Hallock, Michael J. / Luthey-Schulten, Zaida et al. | 2019
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Probing the Biophysical Mechanisms of Infrared Neural Stimulation with Nonlinear Raman ImagingAdams, Wilson R. / Wang, Manqing / Gautam, Rekha / Jansen, E. Duco / Mahadevan-Jansen, Anita et al. | 2019
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Optical Tweezers with IRM, TIRF and Widefield: Studying Cytoskeletalprocesses with or without the Need for Fluorescence LabelingSimpson, Trey / Tafoya, Sara / Au, Ernie / Raja, Ali / Peutz, Willem / Candelli, Andrea / Sitters, Gerrit et al. | 2019
- 277a
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Quantitative Measurements of Single-Molecule FRET between Quantum Dots and Organic DyesShatery Nejad, Nooshin / Etson, Candice M. et al. | 2019
- 280a
-
Type 3 Secretion System Chaperone-Effector Dynamics in Live Yersinia enterocoliticaAchimovich, Alecia M. / Rivera, Alma / Rocha, Julian / Gahlmann, Andreas et al. | 2019
- 281a
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Two-Photon Imaging of NADH in SKH1 Mice Reveals Changes in Keratinocyte Metabolism with Chronic UVA ExposureMyers, Dominick / Sotelo, Katie D. / Frances Gabriel, Marifel / Jackson, Kelsey A. / Yang, Brooke L. / Huerter, Ben G. / Che, Dan L. / Myers, Molly / Nguyen, Duyen / Hansen, Laura A. et al. | 2019
- 282a
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Multifocus Structure Illumination MicroscopyHernandez, Juliana / Abrahamsson, Sara et al. | 2019
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Active PSF Shaping and Adaptive Optics Enable Volumetric Single Molecule Super-Resolution Microscopy through Brain SectionsMlodzianoski, Michael / Cheng-Hathaway, Paul / Liu, Sheng / Bemiller, Shane / McCray, Tyler / Miller, David / Lamb, Bruce / Landreth, Gary / Huang, Fang et al. | 2019
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Electron Paramagnetic Resonance Elucidates the Structural Mechanism by Which SERCA is Activated by DWORFRustad, Mark D. / Martin, Peter D. / Stroik, Daniel R. / Karim, Christine B. et al. | 2019
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Highly Sensitive Resonators for EPR Spectroscopy of Submicroliter/Submicromolar Biomacromolecular SamplesAbhyankar, Nandita / Agrawal, Amit / McMichael, Robert / Veronika, Szalai et al. | 2019
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MAINMAST-MELD-MDFF: Denovo Structure-Determination with Data-Guided Molecular DynamicsPerez, Alberto / Shekhar, Mrinal / Terashi, Genki / Kihara, Daisuke / Dill, Ken A. / Tajkhorshid, Emad / Singharoy, Abhishek et al. | 2019
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Can Hydrogen-Deuterium Exchange Rates at Single Residue Level Be Obtained from HDX-MS Data?Paci, Emanuele / Tuma, Roman / Skinner, Simon / Houwing-Duistermaat, Jeanine J. et al. | 2019
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Automatic Assignment of Bonded Force Field Parameters for Small Molecules Using Machine LearningNarwelkar, Praveer / Sun Lee, Hui / Xie, Sihong / Im, Wonpil et al. | 2019
- 291a
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Unsupervised Learning of Conformational States Present in Molecular Dynamics Simulation Data for Summarization of Equilibrium Conformational DynamicsLutful Kabir, Kazi / Akhter, Nasrin / Shehu, Amarda et al. | 2019
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-
Autochemophoretic DNA Motors Generate 100+ Piconewton ForcesBlanchard, Aaron / Salaita, Khalid et al. | 2019
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Array of Freestanding Planar Lipid Bilayers for Parallel Optical and Electrical RecordingsBaaken, Gerhard / Zaitseva, Ekaterina / Petersen, Soenke / Sych, Taras / Stefan, Kubick / Behrends, Jan C. et al. | 2019
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Flow Imaging Microscopy of a Self-Assembling Protein Polymer MaterialBalog, Eva Rose M. et al. | 2019
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Transcriptional Activation by Glucocorticoid Receptor Studied by 3D Orbital Tracking Fluorescence Cross Correlation SpectroscopyGoelzer, Julianna A. / Stavreva, Diana A. / Hager, Gordon L. / Ferguson, Matthew L. et al. | 2019
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Molecular Mechanism of TRPM2 GatingFu, Tianmin et al. | 2019
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-
Fast, Atomic-Level AFM and Magnetic Tweezers Simulations of the Unfolding of Membrane Proteins using a New Membrane Burial Potential with H-BondingWang, Zongan / Jumper, John M. / Freed, Karl F. / Sosnick, Tobin R. et al. | 2019
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A Pharmacological Masterkey Mechanism to Unlock the Selectivity Filter Gate in K+ ChannelsSchewe, Marcus / Sun, Han / Mackenzie, Alexandra / Pike, Ashley C.W. / Schulz, Friederike / Constantin, Christina / Kiper, Aytug K. / Conrad, Linus J. / Gonzalez, Wendy / de Groot, Bert L. et al. | 2019
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Matrix Ca2+Modulates Mitochondrial Uniporter (MCU) Activity by Flux-through EffectsVais, Horia / Payne, Riley / Daniel Mak, Don-On / Foskett, Kevin J. et al. | 2019
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-
Super-Resolution Imaging of the Brain Extracellular Space Deep within Intact Live Tissue using Carbon NanotubesGodin, Antoine G. / Danné, Noémie / Varela, Juan A. / Zhenghong, Gao / Lounis, Brahim / Groc, Laurent / Cognet, Laurent et al. | 2019
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Single-Molecule Mechanics of the Molecular Spring that Underlies HearingBartsch, Tobias F. / Hengel, Felicitas E. / Oswald, Aaron / Dionne, Gilman / Chipendo, Iris V. / Mangat, Simranjit / El Shatanofy, Muhammad / Mueller, Ulrich / Shapiro, Lawrence / Hudspeth, A.J. et al. | 2019
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A Living, Single Cell View of Myc's Effects on TranscriptionPatange, Simona / Girvan, Michelle / Levens, David / Larson, Daniel R. et al. | 2019
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4D Characterization of Spatiofunctional Enzyme Droplets in Living CellsKyoung, Minjoung et al. | 2019
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Tau Differentially Regulates Kinesin-1, Kinesin-2, and Kinesin-3Lessard, Dominique V. / Berger, Christopher L. et al. | 2019
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Kindlin Dimer Strengthens Focal Adhesions under Force by Relieving and Mediating Intracellular Crosstalk Among IntegrinsJahed, Zeinab / Haydari, Zainab / Rathish, Akshay / Mofrad, Mohammad R.K. et al. | 2019
- 311a
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Selective De-Adhesion Within Intercalated Disk Nanodomains Prompts Proarrhythmic Conduction Slowing in the HeartStruckman, Heather L. / Mezache, Louisa / Greer-Short, Amara / Phillips, Anna / Hund, Thomas J. / Veeraraghavan, Rengasayee et al. | 2019
- 313a
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Investigating Membrane Tension Dynamics in the Neuronal Presynaptic TerminalDudzinski, Natasha / Zenisek, David / Karatekin, Erdem et al. | 2019
- 316a
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Asymmetric Proteoliposomes - Striking a New Path in the World of Model MembranesMarkones, Marie / Fippel, Anika / Kaiser, Michael / Drechsler, Carina / Hunte, Carola / Heerklotz, Heiko H. et al. | 2019
- 318a
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Cryo-EM Structures and Mechanism of Human Multidrug ABC TransportersLocher, Kaspar et al. | 2019
- 319a
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Time-Resolved Contrast Variation SAXS for Studying RNA-Protein InteractionsPabit, Suzette A. / Katz, Andrea M. / Calvey, George D. / Pollack, Lois et al. | 2019
- 320a
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Folding Pathway of a Two-Domain Protein Studied with Single Molecule Three-Color FRETAgam, Ganesh N. / Barth, Anders / Lamb, Don C. et al. | 2019
- 322a
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Multiscale Modeling of Ductal Carcinoma In SituButner, Joseph D. / Cristini, Vittorio / Wang, Zhihui et al. | 2019
- 323a
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Multi-Scale Imaging to Enable Multi-Scale Modeling for Predicting Tumor Growth and Treatment ResponseYankeelov, Thomas / Hormuth, David / Jarrett, Angela / Lima, Ernesto / Wu, Chengyue / Woodall, Ryan / Philips, Caleb et al. | 2019
- 324a
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3D Fluorescence Microscopy Reveals Geometric Localization of Bacterial Cell Shape Proteins in Straight, Curved and Helical RodsBratton, Benjamin P. / Gitai, Zemer / Shaevitz, Joshua W. et al. | 2019
- 325a
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Measuring the Average Shape of Transition Paths during the Folding of a Single Biological MoleculeHoffer, Noel Q. / Neupane, Krishna / Woodside, Michael T. et al. | 2019
- 326a
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Scanning Ion Conductance Microscopy and Atomic Force Microscopy for Live Cell Imaging: A ComparisonSeifert, Jan / Rheinlaender, Johannes / Schäffer, Tilman E. et al. | 2019
- 327a
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Measuring Hindered Diffusion Dynamics in Live Cell Plasma Membranes with Confocal and Super-Resolution ImagingSchneider, Falk / Sezgin, Erdinc / Waithe, Dominic / Fritzsche, Marco / Eggeling, Christian et al. | 2019
- 328a
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Budding and Fission of Vesicles by Control of Membrane Spontaneous CurvatureSteinkühler, Jan / Bartelt, Solveig / Wegner, Seraphine / Knorr, Roland L. / Dimova, Rumiana / Lipowsky, Reinhard et al. | 2019
- 329a
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Prototyping Multiscale Cellular Visualization & Modeling Techniques for Hypothesis Generation, Communication & LearningJohnson, Graham et al. | 2019
- 330a
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Towards Near-Atomic Resolution for In Situ Structures by Cryo-Electron TomographyZhang, Peijun et al. | 2019
- 332a
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Rational Targeting and Testing of Mycobacterial L-Asparaginase, Essential for Survival of MtB Inside HostsKataria, Arti / Kundu, Bishwajit et al. | 2019
- 334a
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Application of Numerical Simulations to Extract Protein Folding Parameters from Hydrogen Exchange Mass Spectrometry Experiments under Native ConditionsFlint, Jasper / Aghera, Nilesh K. / Varadarajan, Raghavan / Jaswal, Sheila et al. | 2019
- 335a
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The Effect of Input Set to Consensus Derived Proteins and their Relationship to Ancestral ProteinsNixon, Charlotte / Lim, Shion A. / Harms, Michael / Marqusee, Susan et al. | 2019
- 336a
-
Measuring the Unfolding and Ligand-Binding of CusF, a Copper ChaperoneZecua, Isabel / Gillespie, Blake et al. | 2019
- 337a
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A Decoy Folding Nucleus can Modulate Protein Folding KineticsDas, Anirban / Yadav, Anju / Gupta, Mona / Purushotham, R. / Terse, Vishram L. / Gosavi, Shachi / Das, Ranabir / Koti Ainavarapu, Sri Rama / Maiti, Sudipta et al. | 2019
- 338a
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Effect of Hsp70 Chaperone on CNG Ion Channels Related to ChannelopathiesJuárez, Karina / Lopez-Rodriguez, Angelica / Meneses-Morales, Ivan et al. | 2019
- 340a
-
What Modulates the Usp7 Function...A Dynamic Pocket or Inter-Regulatory Domains?Srivastava, Mitul / Suri, Charu / Asthana, Shailendra et al. | 2019
- 341a
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High Bandwidth Sensing of Single Protein Dynamics using Nanopores and DNA OrigamiSchmid, Sonja / Stoemmer, Pierre / Dietz, Hendrik / Dekker, Cees et al. | 2019
- 343a
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Single Point Mutations Modulate Dynamical Allostery in IgG4 Monoclonal AntibodiesBaker, Lonnie / Uddin, Shahid / Singam, Azhagiya / Jacobs, Donald J. / Casas-Finet, Jose et al. | 2019
- 345a
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Determining the Unbinding Pathway for a TSPO-PK11195 ComplexDixon, Thomas / Dickson, Alex et al. | 2019
- 346a
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Molecular Determinants of Neisserial Opa Protein Interactions with Human CEACAMsMartin, Jennifer N. / Criss, Alison K. / Columbus, Linda et al. | 2019
- 350a
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Using Site-Specific Vibrational Spectroscopy to Determine Structure of Membrane-Bound N-Terminally Acetylated Alpha-SynucleinMcCalpin, Samuel / Kostas, Franklin / Londergan, Casey H. et al. | 2019
- 351a
-
Amyloid -Beta Oligomerization in the Presence of Anionic PhospholipidsSaha, Jhinuk / Dean, Dexter N. / Rangachari, Vijay et al. | 2019
- 352a
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Functional Somatic Exosomal Noncoding ncRNA by Modular Biocombinatorics and Algorithms: From Genetic Introns to Codes for Epigenetic FunctionsWissler, Josef H.H. et al. | 2019
- 353a
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RNA Structure and Kinetics Including Pseudoknots through Complete Landscape EnumerationKimchi, Ofer / Cragnolini, Tristan / Garmann, Rees / Manoharan, Vinothan N. / Brenner, Michael P. / Colwell, Lucy J. et al. | 2019
- 354a
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Pressure Effects on Folding of an RNA G-Quadruplex StructureHarish, Balasubramanian / Wang, Jinqiu / Hayden, Eric / Royer, Catherine et al. | 2019
- 355a
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Solution Structure of a C-Jun 5′ UTR Stem-Loop Associated with Cap-Dependent eIF3 Specialized Translation InitiationWalker, Matthew et al. | 2019
- 356a
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Characterization of Structural Elements in the HCV Genome using Atomic Force MicroscopyGilmore, Jamie L. / Aizaki, Hideki / Wakita, Takaji / Takeyasu, Kunio et al. | 2019
- 358a
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Effect of Tetrameric Base-Pair Context on the Sequence-Dependent Configurations of DNA MinicirclesYoung, Robert T. / Cohen, Benjamin / Czapla, Luke / Perez, Pamela J. / Olson, Wilma K. et al. | 2019
- 360a
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The Genetic Code is Read by an Idiosyncratic and Highly-Connected Decoding NetworkFried, Stephen D. / Elliott, Thomas S. / Wagner, Mirko / Carell, Thomas / Chin, Jason W. et al. | 2019
- 361a
-
A High-Resolution In Vitro Single-Molecule Assay for Eukaryotic Cap-Dependent Initiation KineticsQu, Xiaohui / Wang, Hongyun / Gaba, Anthony / Sun, Lexi et al. | 2019
- 364a
-
MthK Channel Activity in Planar Tetraether Lipid MembranesBonanno, Alexander P. / Vouga, Alexandre G. / Rothberg, Brad S. / Chong, Parkson L.-G. et al. | 2019
- 365a
-
The Durability of Lipid Bilayers Modified with a Minimal Actin Cortex (MAC) for Nanopore Sensing and Ion Channel ElectrophysiologySmith, Amanda J. / Larsen, Theo / Virolainen, Samuel / Burden, Lisa / Burden, Daniel L. et al. | 2019
- 366a
-
Establishing Force Spectrscopy with Lipid Vesicle Probes towards the Investigation of Membrane FusionLüchtefeld, Ines / Zambelli, Tomaso / Vörös, Janos et al. | 2019
- 367a
-
Synergistic Roles of Synaptotagmin and Complexin in Ca2+-Regulated ExocytosisKrishnakumar, Shyam S. et al. | 2019
- 368a
-
Molecular Mechanisms of the Interaction between Arf1 and ASAP1 pH Domain at the Membrane InterfaceSoubias, Olivier / Heinrich, Frank / Zhang, Yue / Li, Yifei / Li, Jess / Silin, Vitalii I. / Randazzo, Paul / Losche, Mathias / Byrd, Robert A. et al. | 2019
- 369a
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Regulation of the Palmitoyl Acyltransferase DHHC5 by Phosphorylation in CardiomyocytesMarsden, Autumn N. / Chen, Jie J. / Scott, C. Anthony / Akimzhanov, Askar M. / Boehning, Darren et al. | 2019
- 372a
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Substrate Binding by γ-Secretase: Conformational Dynamics of the Enzyme Active Site and Substrate Recognition with an Example of the Amyloid Precursor ProteinPiotr Nierzwicki, Lukasz / Olewniczak, Michal / Chodnicki, Pawel / Czub, Jacek et al. | 2019
- 373a
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Advancing Multi-Scale Simulation Methods for Biological Membrane SystemsBrandner, Astrid F. / Timr, Stepan / Melchionna, Simone / Derreumaux, Philippe / Baaden, Marc / Sterpone, Fabio et al. | 2019
- 374a
-
A Molecular Mechanism for Membrane Geometry-Specific Protein LocalizationKockelkoren, Gabriele et al. | 2019
- 375a
-
Classification of Different Cancer Cell Types by Species Specificity for Cell ElasticityKwon, Sangwoo / Jik Han, Se / Sook Kim, Kyung et al. | 2019
- 376a
-
Bile Canaliculi Contractility Is Regulated by Canalicular Pressure Sensing via PIEZO1Gupta, Kapish / Chuan Ng, Inn / Low, Boon C. / Yu, Hanry et al. | 2019
- 378a
-
The Bacterial Mecanosensitive Channel MscL as a Novel Antibiotic TargetIscla, Irene / Wray, Robin / Blount, Paul et al. | 2019
- 381a
-
Different Context for Shear Signaling in Left Versus Right Atrial Myocytes: Differential Roles of P2Y1- and P2X4-PurinoceptorsKim, Joon-Chul / Son, Min-Jeong / Le, Qui A. / Kim, Kyoung-Hee / Woo, Sun-Hee et al. | 2019
- 382a
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TRPV4 Contributes to Stretch-Induced Hypercontractility and Time-Dependent Dysfunction in Hearts of Aged MiceVeteto, Adam B. / Lambert, Michelle D. / McDonald, Kerry S. / Domeier, Tim L. et al. | 2019
- 383a
-
Triggered Calcium Events Reveal Electrophysiological Alterations in a Cohort of Patients Susceptible to Malignant HyperthermiaFigueroa, Lourdes / Kraeva, Natalia / Manno, Carlo / Tammineni, Eshwar R. / Riazi, Sheila / Rios, Eduardo et al. | 2019
- 384a
-
Activation of Endogenous PP1 Enhances Calcium Spark Activity in Wild Type CardiomyocytesJanicek, Radoslav / Michele Potenza, Duilio / Fernandez-Tenorio, Miguel / Valdivia, Hector H. / Niggli, Ernst et al. | 2019
- 385a
-
Myosin Binding Protein-C Slow in Health and DiseaseGeist, Janelle / Stavusis, Janis / Lace, Baiba / Wright, Nathan T. / Ward, Christopher W. / Bonnemann, Carsten / Kontrogianni-Konstantopou, Aikaterini et al. | 2019
- 387a
-
Protx-II Inhibits Nav1.7 through an Electrostatic Gating Modulation MechanismLi, Tianbo et al. | 2019
- 388a
-
Biophysical and Pharmacological Profiling of Multiple Voltage-Gated Sodium Channel Subtypes on QPatch IISauter, Daniel R. / Jacobsen, Rasmus B. / Mattsson, Goeran et al. | 2019
- 389a
-
The Insecticide Fenvalerate Binds to NavMs Sodium Channels, Making them a Suitable Template for Modelling Structures of Housefly-Insecticide ComplexesSula, Altin / Molnar, Edina / Wallace, Bonnie A. et al. | 2019
- 390a
-
Cardiac Sodium Current is Severely Impaired in Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Brugada Syndrome PatientsMartinez-Moreno, Rebecca / Selga, Elisabet / Sarquella-Brugada, Georgia / Brugada, Ramon / Perez, Guillermo / Scornik, Fabiana et al. | 2019
- 391a
-
Effect of Hyperglycemia in the Activity of Glycine Receptors in Insulin Secreting CellsSchukarucha Gomes, Amanda / Bordin, Silvana / Abdulkader, Fernando et al. | 2019
- 393a
-
Role of the Cytoplasmatic M3-M4 Loop for the Homopentameric Assembly of a Chimeric Nicotinic Alpha 7 ReceptorDeppe, Jonas / Hauswirth, Lena / Lauks, Heike / Kless, Achim / Hausmann, Ralf / Schmalzing, Guenther et al. | 2019
- 395a
-
Understanding the Conformational Dynamics of a Pentameric Ligand-Gated Ion Channel through Markov State ModelingBergh, Cathrine C. / Orellana, Laura / Howard, Rebecca J. / Lindahl, Erik et al. | 2019
- 397a
-
KCNQ1/KCNE1 Membrane Expression is Regulated by the Membrane Phosphoinosite PI4P: Consequences for Long QT1Braun, Chen / Lopes, Coeli et al. | 2019
- 398a
-
Systematic Scanning Mutagenesis of the Pore Helices in the TREK-2 K2P ChannelArcangeletti, Manuel / Tucker, Stephen J. et al. | 2019
- 399a
-
Dissecting the Structure and Function of Bestrophin ChannelsKittredge, Alec / Ji, Changyi / Hopiavuori, Austin / Ward, Nancy / Chen, Shoudeng / Fukuda, Yota / Zhang, Yu / Yang, Tingting et al. | 2019
- 401a
-
A Drosophila Cardiac Myosin Isoform Enables Jump Muscle Cyclical Power ProductionBell, Kaylyn M. / Swank, Douglas M. et al. | 2019
- 403a
-
Time-Resolved X-Ray Diffraction and Molecular Dynamics Studies of Skeletal Muscle Relaxation with 2 Deoxy-ATPMa, Weikang / Childers, Matthew C. / Murray, Jason D. / Gong, Henry / Daggett, Valerie / Irving, Thomas C. / Regnier, Michael et al. | 2019
- 404a
-
Regulation of Myofilament Force and Loaded Shortening by Skeletal Myosin Binding Protein-CRobinett, Joel C. / Hanft, Laurin M. / Geist, Janelle / Kontrogianni-Konstantopoulos, Aikaterini / McDonald, Kerry S. et al. | 2019
- 405a
-
Impaired Redox Capacity, Muscle Injury, and Microtubule Alterations Conspire to Impact Skeletal Muscle FunctionVanegas, Camilo et al. | 2019
- 407a
-
Dynamical Effects of KIF1A Mutations in Neurodevelopmental DisordersJariwala, Shashank / Budaitis, Breane G. / Verhey, Kristen J. / Sept, David et al. | 2019
- 408a
-
Atomistic Details of the Dynein Motor Mechanism Revealed by Molecular Dynamics SimulationsHadden, Jodi A. / Goldman, Yale E. et al. | 2019
- 409a
-
DDB Switches between Processive and Diffusive RunsFeng, Qingzhou / Hancock, William O. et al. | 2019
- 413a
-
Determination of Fibroblast Polarization under the Combination of Physical, Molecular, and Genetic CuesLee, GeonHui / Kim, Dong-Hwee et al. | 2019
- 414a
-
Constricted Migration Increases DNA Damage and Represses Cell CyclePfeifer, Charlotte R. / Xia, Yuntao / Fang Hum, Yee / Zhu, Kuangzheng / Liu, Dazhen / Irianto, Jerome / Boot, Ruben C. / Morales Garcia, Victor M. / Santiago Millan, Leeza M. / Niese, Brandon et al. | 2019
- 415a
-
Molecular Force of Airway Smooth Muscle Cell during ContractionHyun Jo, Myung / Choul Kim, Byoung / An, Steven S. / Ha, Taekjip et al. | 2019
- 417a
-
Structural Analysis of Saccharomyces cerevisiae Respiratory Supercomplex Composed of Complexes III and IVMileykovskaya, Eugenia / Baker, Matthew / Mallampalli, Venkata / Fan, Guizhen / Serysheva, Irina I. / Dowhan, William et al. | 2019
- 418a
-
Performance of a Bacterium as an Energy Conversion Device in Terms of Energy-Return-On-Investment Determined from Atomic-Detail Structural ModelsSener, Melih / Hitchcock, Andrew / Hunter, Neil et al. | 2019
- 419a
-
Modeling of Protein Complex Architectures using Combinatorial Genetic PerturbationsEcheverria, Ignacia / Braberg, Hannes / Cimermancic, Peter / Pellarin, Riccardo / Schneidman, Dina / Shiver, Anthony / Gross, Carol / Krogan, Nevan / Sali, Andrej et al. | 2019
- 420a
-
Functional Interpretation of Single Amino Acid Substitutions in 1, 330 Disease-Associated GenesIqbal, Sumaiya / Berg Jespersen, Jakob / Perez-Palma, Eduardo / May, Patrick / Palotie, Aarno / Cottrell, Jeffrey R. / Wagner, Florence F. / Daly, Mark J. / Campbell, Arthur J. / Lal, Dennis et al. | 2019
- 422a
-
Development of an Integrated Human Model of Electrophysiology and Actin-Myosin Binding to Describe Sarcomere Force Generation in CardiomyocytesAbrams, Ruth E. / Schneider, Hans-Christoph / Radziun, Tatiana / Goebel, Britta / Lucats, Laurence / Azer, Karim / Surks, Howard / Sobie, Eric / Stamatelos, Spyros et al. | 2019
- 423a
-
Structure-Based Method for Predicting Deleterious Missense SNPsWang, Boshen / Lei, Xue / Tian, Wei / Perez-Rathke, Alan / Tseng, Yanyuan / Liang, Jie et al. | 2019
- 425a
-
Construction of an Openspim Light-Sheet Microscope for the Study of Neural Crest Migration in Danio RerioRocha, Manuel / Reyer, Matt / Alvarado, Walter / Glauninger, Hendrik / Hoinville, Megan / Kroll, Kourtney / MacDonald, Margo / Rouviere, Eric / Schnitkey, Diane / Veseli, Iva et al. | 2019
- 427a
-
Binding and Transport of Amyloid-β by P-Glycoprotein: A Novel Therapeutic Target in Alzheimer's DiseaseHolt, Hope / Moore, Elizabeth / Riese, Madeline / Faucett, Michelle / Gonzalez, Francisco / Moss, Melissa et al. | 2019
- 428a
-
Molecular Resolution of Gram Positive Bacteria Cell Wall using AFMPasquina Lemonche, Laia / Burns, Jonathan / Turner, Robert / Foster, Simon / Hobbs, Jamie et al. | 2019
- 429a
-
Investigating Cell Stiffness in Wild-Type Candida albicans and its Morphologies using Contact Atomic Force MicroscopyAsh, Michelle K. / Stephens, Jeff D. et al. | 2019
- 430a
-
Exploring the Sulfatase 1 Catch Bond Free Energy Landscape using Jarzynski's EqualityWalhorn, Volker / Moeller, Ann-Kristin / Bartz, Christian / Dierks, Thomas / Anselmetti, Dario et al. | 2019
- 431a
-
The Neutron Spin Echo Spectrometer at SNS and its Biophysics ApplicationsStingaciu, Laura R. et al. | 2019
- 433a
-
Structural Insights into the Activation of Blood Coagulation Factor XI Zymogen by Thrombin: A Computational Molecular Dynamics StudyVenkateswarlu, Divi et al. | 2019
- 434a
-
Theoretical Modeling of the RNA-Enhanced NTPase Activity of Dengue and Zika NS3 HelicasesDavidson, Russell B. / McCullagh, Martin et al. | 2019
- 435a
-
Activation of the Voltage Gated Proton Channel Hv1: A Constant pH Molecular Dynamics StudyHenderson, Jack A. / Shen, Jana et al. | 2019
- 436a
-
Peptide Binding Interaction between ArkA and Abp1SH3 using Markov State ModelsHuang, Henry / Gerlach, Gabriella et al. | 2019
- 438a
-
A Novel Viewpoint to Analyze Structured Illumination Microscopy (Sim) DataCainero, Isotta / Pelicci, Simone / Di Bona, Melody / Diaspro, Alberto / Lanzano', Luca et al. | 2019
- 439a
-
Live Cell Super-Resolution Imaging with Red-Shifted States of Conventional Bodipy FluorophoresAdhikari, Santosh / Moscatelli, Joe / Puchner, Elias et al. | 2019
- 440a
-
Taking a Closer Look at Bacterial:Fungal Interactions in Soil using Quantitative MicroscopyMorales, Demosthenes P. / Werner, James H. et al. | 2019
- 444a
-
Nanopore-Nanoelectrode for Potential Sensing of Single Nanoparticle Collision EventsPandey, Popular / He, Jin et al. | 2019
- 445a
-
Comparative Physicochemical Characterization between Brand and Generic Intravenous Sodium Ferric Gluconate Complex in Sucrose InjectionBrandis, Joel / Taraban, Marc / Kihn, Kyle / Neu, Heather / Langguth, Peter / Confer, Alex / Goldberg, David / Polli, James / Michel, Sarah et al. | 2019
- 447a
-
Simulation of the Motion of Arbitrarily Shaped Protein Molecules in Nanopores using Clusters of Rigid Spherical ParticlesXu, Shuran / Lattuada, Marco / Mayer, Michael et al. | 2019
- 449a
-
Integrating Fundamental Biophysics Research in Emphasis Courses for Engineering and Agricultural Sciences StudentsVega, Katherine / Ochoa, Samuel / Herrera, Jorge A. / Patino, Luis F. / Gomez, Jorge A. / Quijano, Jairo C. et al. | 2019
- 451a
-
Approaching to the Molecular Mechanism of the Fast Inactivation of Calcium Selective TRP ChannelsFlores Aldama, Lisandra / Zavala, Kattina / Bustos, Daniel / Gonzalez, Wendy / Opazo, Juan / Brauchi, Sebastian E. et al. | 2019
- 452a
-
Tardigrade Intrinsically Disordered Proteins Protect Enzymes from Desiccation-Induced InactivationPiszkiewicz, Samantha / Gunn, Kathryn H. / Speer, Shannon L. / Warmuth, Owen / Mehta, Aakash / Lauzier, Francis J. / Nguyen, Kenny H. / Kuhlman, Elizabeth / Neher, Saskia B. / Pielak, Gary J. et al. | 2019
- 453a
-
Sequence Determinants of Protein Phase Separation of the Intrinsically Disordered RGG Domain from LAF-1Schuster, Benjamin S. / Dignon, Gregory / Jahnke, Craig / Good, Matthew C. / Hammer, Daniel A. / Mittal, Jeetain et al. | 2019
- 454a
-
Structural and Mechanistic Bases of Drp1-Cardiolipin Interactions in Mitochondrial FissionLu, Bin / Mahajan, Mukesh / Mandal, Abhishek / Bharambe, Nikhil / Wang, Rihua / van der Wel, Patrick / Buck, Matthias / Qi, Xin / Ramachandran, Rajesh et al. | 2019
- 455a
-
Characterization of Phosphatidylinositol Phosphate Binding in Lipid Bilayers by Solid-State NMR SpectroscopyPerodeau, Jacqueline R. / Bernstein, Ashley D. / Lazieh, Stefany M. / Palmere, Robert D. / Nieuwkoop, Andrew J. et al. | 2019
- 456a
-
Different Faces (Phases) of Actin Depolymerizing Factors from Entamoeba Histolytica.Parimita Rath, Pragyan / Kumar, Nitesh / Gourinath, Samudrala et al. | 2019
- 457a
-
Hydroxylation of Type I Collagen: Effects on Fibrillar Structure and MechanicsKandoor, Alekhya A. / Kirchner, Michele / Wineman-Fisher, Vered / Xu, Yujia / Varma, Sameer et al. | 2019
- 458a
-
Dissection of Protein Function Within a Bacterial Biomolecular Condensate by In Vitro ReconstitutionSaurabh, Saumya / Shapiro, Lucy et al. | 2019
- 461a
-
Acute Loss of cMyBP-C Induces Auto-Oscillatory Contractions in Permeabilized Cardiomyocytes: Implications for Reverse E-C Coupling?Harris, Samantha P. et al. | 2019
- 462a
-
Rhodopsin Hydration Dynamics Studied by Solid-State Deuterium NMR SpectroscopyWeerasinghe, Nipuna / Perera, Suchitranga M.D.C. / Molugu, Trivikram R. / Salinas, Andres M. / Brown, Michael F. et al. | 2019
- 463a
-
Graph Spectral Properties of the Sidechain Networks of Protein Structures: Implications to Allostery and Structure ComparisonVishveshwara, Saraswathi / Dighe, Anasuya / Gadiyaram, Vasundhara et al. | 2019
- 464a
-
Improvement of Maturation State of Human Induced Pluripotent Stem Cell-Derived 3D Cardiac Microtissues by Defined Chemical FactorsYu Huang, Chen / Joca, Rebeca / Siang Ong, Chin / Wilson, Ijala / Teuben, Roald / Tomaselli, Gordon F. / Reich, Daniel H. et al. | 2019
- 465a
-
Protein Phase Transition: From Biology Towards New Protein MaterialsLinsenmeier, Miriam / Küffner, Andreas / Faltova, Lenka / Hondele, Maria / Weis, Karsten / Arosio, Paolo et al. | 2019
- 466a
-
On the Functional Assessment of Hypertrophic Cardiomyopathy-Causing Mutations in Human β-Cardiac Myosin and the Role of Myosin Binding Protein-CTrivedi, Darshan V. / Sarkar, Saswata S. / Adhikari, Arjun S. / Morck, Makenna M. / Kooiker, Kristina B. / Bernstein, Daniel / Ruppel, Kathleen M. / Spudich, James A. et al. | 2019
- 467a
-
Shelterin Components Modulate the Phase-Separation Propensity of TelomeresSoranno, Andrea / Incicco, Jeremias / De Bona, Paolo / Tomko, Eric / Galburt, Eric / Galletto, Roberto et al. | 2019
- 468a
-
Multiple Interaction Modes of the Nucleosomal Histone H3 N-Terminal Tail Revealed by High Precision Single-Molecule FRETLehmann, Kathrin / Felekyan, Suren / Kühnemuth, Ralf / Dimura, Mykola / Tóth, Katalin / Seidel, Claus A.M. et al. | 2019
- 469a
-
Integrative Dynamic Structural Biology with Fluorescence SpectroscopySeidel, Claus A.M. / Dimura, Mykola / Sanabria, Hugo / Hemmen, Katherina / Peulen, Thomas-Otavio / Rodnin, Dmitro / Gohlke, Holger et al. | 2019
- 471a
-
The Microphthalmia-Associated Transcription Factor Associates with Multiple Domains of CBP/P300, Including the E1A Binding Face of TAZ2Vergunst, Kathleen / Brown, Alexandra / Branch, Makenzie / Langelaan, David N. et al. | 2019
- 473a
-
Studying Mutations in Geobacillus kaustophilus Tils to Probe Changes in Structure and Mobility using Molecular Dynamic (MD) SimulationsGuinto, Ferdiemar C. / Alexander, Rebecca W. et al. | 2019
- 474a
-
Structure and Function of Human Vitronectin, a Key Mediator of Host-Pathogen InteractionsShin, Kyungsoo / Fujimoto, L. Miya / Meneghini, Luz M. / Singh, Chandan / Yao, Yong / Tian, Ye / Marassi, Francesca M. et al. | 2019
- 475a
-
Exploring the Effect of Preorganization on Binding Affinity in Cyclized PeptidomimeticsTerry, Allison / Voelz, Vincent et al. | 2019
- 476a
-
Studying Complex Biomolecular Dynamics by Single-Molecule Three-Color FRETBarth, Anders / Seidel, Claus A.M. / Lamb, Don C. et al. | 2019
- 477a
-
Peptide Assisted Supramolecular Polymerization of the Anionic Porphyrin Meso-Tetra(4-Sulfonatophenyl)PorphineKohn, Eric / Shirly, David / Fry, Christopher H. / Caputo, Gregory A. et al. | 2019
- 478a
-
Structural Bases for Chemical and Mechanical Gating in the Piezo1 ChannelBotello-Smith, Wesley M. / Zhang, Han / Ozkan, Alper D. / Jiang, Wenjuan / Pham, Christine N. / Luo, Yun / Lacroix, Jerome J. et al. | 2019
- 479a
-
Inhibition of Zinc-Mediated Amyloid Beta Aggregation and Cytotoxicity by Alpha Helix MimeticsVogel, Maria C. / Kumar, Sunil / Maity, Debabrata / Magzoub, Mazin M. / Hamilton, Andrew D. et al. | 2019
- 482a
-
Edema Factor Of Bacillus Anthracis Interacting with its InhibitorsPitard, Irène / Simenel, Catherine / Monet, Damien / Thomas, Christophe / Suzanne, Peggy / Blondel, Arnaud / Bellalou, Jacques / Dallemagne, Patrick / Guijarro, Inaki / Ladant, Daniel et al. | 2019
- 484a
-
Characterizing HP1-Driven Chromatin Compaction using Nuclear Magnetic Resonance SpectroscopyAckermann, Bryce E. / Debelouchina, Galia T. et al. | 2019
- 485a
-
The Placement of Vibrational Probe Labeled Substrates to the Phosphopantetheine Arm of the E.Coli Acyl Carrier Protein for Site Specific Vibrational SpectroscopyLing, Joie / von Krusenstiern, Eliana V. / Kokona, Bashkim / Charkoudian, Louise / Londergan, Casey H. et al. | 2019
- 486a
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Anomalous Non-Gaussian Viscoelastic and Age-Dependent Dynamics of Histone-Like H-NS Proteins in Live Escherichia coliSadoon, Asmaa / Wang, Yong et al. | 2019
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Salt Bridges in Ubiquitin Determine the Protein Conformational FlexibilityBhattacharya, Shrabasti / Acharya, Nidhi / Rama Koti Ainavarapu, Sri et al. | 2019
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Dynamical Comparison between Myoglobin and Hemoglobin Reveals the Effect of the Quaternary Structure of Hemoglobin on its Subunits' DynamicsAharoni, Rotem / Tobi, Dror et al. | 2019
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Molecular Analysis of Dengue NS3 Helicase FunctionPont, Kelly E. Du / Davidson, Russell B. / Geiss, Brian J. / McCullagh, Martin et al. | 2019
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Structure and Dynamics of Intrinsically Disordered and Unfolded Proteins: Investigations using Small-Angle Scattering and Neutron Spin-Echo SpectroscopyAmeseder, Felix / Stingaciu, Laura R. / Radulescu, Aurel / Holderer, Olaf / Falus, Peter / Monkenbusch, Michael / Biehl, Ralf / Richter, Dieter / Stadler, Andreas M. et al. | 2019
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Understanding and Preventing Aggregation in Alpha-SynucleinLapidus, Lisa J. et al. | 2019
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Sumoylation of the Nt17 Domain of Huntingtin Influences Aggregation and Binding to Lipid MembranesSedighi, Faezeh / Legleiter, Justin A. et al. | 2019
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Investigating C99 in Amyloid Formation using Molecular Dynamics: From Simple to Complex Neuronal ModelsPin-Chia Hsu, Jenny / Schiøtt, Birgit et al. | 2019
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Alpha-Synuclein Disrupts Inter-Membrane InteractionsChung, Peter J. / Zhang, Qingteng / Luke Hwang, Hyeondo / Leong, Alessandra / Dufresne, Eric / Narayan, Suresh / Adams, Erin J. / Lee, Ka Yee C. et al. | 2019
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Tau Amyloid Aggregates: The Choice of Pathways Makes the DifferenceFichou, Yann / Han, Songi et al. | 2019
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Characterization of the Early Stages of Tau Aggregation in the Presence of PolyphosphatesWickramasinghe, Sanjula P. / Merens, Hope E. / Lempart, Justine / Jakob, Ursala / Rhoades, Elizabeth et al. | 2019
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Dimeric FkpA Acts as an Anti-Aggregase on a Native Unfolded Membrane Protein ClientRoskopf, Michaela A. / Marx, Dagan C. / Plummer, Ashlee M. / Bubb, Quenton R. / Fleming, Karen G. et al. | 2019
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To Kink or Not to Kink: Sequence-Dependent DNA Flexibility Unveiled in Complex with DNA-Bending Protein IHFConnolly, Mitchell / Arra, Aline / Zvoda, Viktoriya / Steinbach, Peter J. / Rice, Phoebe / Ansari, Anjum et al. | 2019
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Long-Range Slippery Hairpin Reconfiguration and its Mechanism in Trinucleotide Repeats Revealed by Single-Molecule SpectroscopyLee, I-Ren / Ni, Cheng-Wei / Wei, Yu-Jie / Shen, Yang-I / Chen, Chien et al. | 2019
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Structural Characterization of a Peptide Derived from a Lab-Evolved Protein that Targets HIV-1 TAR RNAShashank Chavali, Sai / Belashov, Ivan / Jenkins, Jermaine / Wedekind, Joseph et al. | 2019
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Investigating the DNA Binding Activity of the Polybromo-1 BromodomainsDe Silva, Saumya M. / Shangguan, Yangtian / Weaver, Tyler M. / Lupo, Brianna E. / Musselman, Catherine A. et al. | 2019
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Single-Stranded DNA Binding and Crosslinking Activities of the Viral Restriction Factor Apobec3G Characterized by Force SpectroscopyRouzina, Ioulia F. / Morse, Michael / Naufer, Nabuan / Feng, Yuqing / Chelico, Linda / Williams, Mark C. et al. | 2019
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Structural Rearrangement of DNA for CRISPR-Cas9 Nuclease Specificity Regulated by the REC2 DomainSung, Keewon / Park, Jinho / Kim, Younggyu / Ki Lee, Nam / Keun Kim, Seong et al. | 2019
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Protonation States and Conformations of Inositol and Phosphoinositol Phosphates from Molecular SimulationsRadak, Brian et al. | 2019
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Amino Acids Bind to and Influence the Structure of Fatty Acid VesiclesCohen, Zachary R. / Ramsay, Andrew / Cornell, Caitlin E. / Black, Roy A. / Keller, Sarah L. et al. | 2019
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Biophysical Approaches Toward Understanding the Molecular Mechanism of Action of the Mitochondrial Therapeutic SS-31 (Elamipretide)Alder, Nathan N. / Mitchell, Wayne / Ng, Emily / Boyd, Kevin / Tamucci, Jeffrey / May, Eric / Eddy, Nicholas / Szeto, Hazel et al. | 2019
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Using pH Sensitive Peptides for the Endosomal Release of AntibodiesWu, Eric / Kim, Sarah Y. / Hristova, Kalina / Wimley, William C. et al. | 2019
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Ebola Virus Delta-Peptide Acts as an Enterotoxic Viroporin In VivoGuha, Shantanu / Melnik, Lilia / Garry, Robert F. / Wimley, William C. et al. | 2019
- 517a
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Protein-Lipid Interactions Regulate Atg3 Activity in AutophagyTyndall, Erin R. / Ye, Yansheng / Tang, Zhenyuan / Wang, Hong-Gang / Tian, Fang et al. | 2019
- 519a
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Capturing Dynamic Transporter-Lipid InteractionsPolitis, Argyris et al. | 2019
- 520a
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Mutation Analysis of the Calcium Binding Site of Skeletal Muscle Ryanodine Receptor Calcium Release ChannelChirasani, Venkat R. / Xu, Le / Carter, Jordan S. / Addis, Hannah G. / Pasek, Daniel A. / Dokholyan, Nikolay V. / Meissner, Gerhard / Yamaguchi, Naohiro et al. | 2019
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Investigation of Mutant Ryanodine Receptor Channel Activity using Functional Analysis and Molecular DynamicsYamazawa, Toshiko / Ogawa, Haruo / Yamaguchi, Maki / Murayama, Takashi / Oyamada, Hideto / Suzuki, Junji / Kurebayashi, Nagomi / Kanemaru, Kazunori / Sakurai, Takashi / Masamitsu, Iino et al. | 2019
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Mathematical Model to Simulate Sr Calcium Release in Mammalian Skeletal Muscle with Impaired T-Tubular StructureJacquemond, Vincent / Szentesi, Peter / Kutchukian, Candice / Dienes, Beatrix / Csernoch, Laszlo et al. | 2019
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NS510, a High Affinity Fluorescent Catecholamine Sensor for Monitoring Norepinephrine ExocytosisLiu, Xin A. / Zhang, Le / Glass, Timothy / Gillis, Kevin D. et al. | 2019
- 524a
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Alpha to Beta Cells: A Pathway Towards a Diabetes CureDiGruccio, Michael R. / Piston, Dave W. et al. | 2019
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Synaptotagmin-7 Endows a Subpopulation of Chromaffin Granules with Distinct Calcium Sensing and Fusion PropertiesBendahmane, Mounir / Chapman-Morales, Alina / Schenk, Noah A. / Shuang, Zhang / Jenkins, Paul M. / Giovannucci, David R. / Anantharam, Arun et al. | 2019
- 526a
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Structural Characterization of Full-Length Synaptotagmin-1 to Cis or Trans MembranesNyenhuis, Sarah B. / Cafiso, David S. et al. | 2019
- 529a
-
Importance of Ordered Environment in the Early Stage of Mast Cell Signaling Studied by Imaging Fluorescence Correlation SpectroscopyBag, Nirmalya / Holowka, David A. / Baird, Barbara A. et al. | 2019
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A Membrane-Activated, Universal T-Cell Receptor AgonistWilhelm, Kiera B. / Coyle, Michael P. / O'Donoghue, Geoffrey P. / Lin, Jenny JY / Low-Nam, Shalini T. / Groves, Jay T. et al. | 2019
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Total Reconstitution of Receptor-Mediated Ras Activation by SOS in Vitro Reveals Kinetic and Conformational Layers of Regulation in MAPK SignalingAlvarez, Steven / Huang, William Y.C. / Monatrice Lam, Hiu Yue / Low-Nam, Shalini T. / Kwang Lee, Young / Chung, Jean K. / Hansen, Scott D. / Kondo, Yasushi / Biswas, Kabir H. / Kuriyan, John et al. | 2019
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Protein Kinase a Dynamics are Altered at the Outer Mitochondrial Membrane in Cardiac Sympathetic Neurons from Prehypertensive RatsLi, Dan / Tarafdar, Adib / Liu, Kun / Paterson, David J. et al. | 2019
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Short- and Long-Distance Allosteric Coupling in Capsaicin-Induced TRPV1 ActivationVu, Simon / Hyun Lee, Bo / Xiao, Xian / Yang, Fan / Zheng, Jie et al. | 2019
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Understanding Protein-Lipid Interactions of TRP Channels of the Polycystin Family, through MD Simulations and Structural StudiesWang, Qinrui / Hedger, George / Aryal, Prafulla / Grieben, Mariana / Pike, Ashley C.W. / Shi, Jiye / Carpenter, Elisabeth P. / Sansom, Mark S.P. et al. | 2019
- 535a
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Selectivity and Characterization of the Permeant Ion Effect in the Rapidtransitions on the Pore of TRPV1 ChannelGarcia Avila, Miriam / Tello Marmolejo, Javier / Rangel-Yescas, Gisela E. / Islas, Leon D. et al. | 2019
- 537a
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Investigation of TRPM4 in Prostate Cancer Cells with Novel Small Molecule InhibitorsBorgström, Anna / Hauert, Barbara / Kappel, Sven / Delalande, Clémence / Reymond, Jean-Louis / Peinelt, Christine et al. | 2019
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Spectroscopic Studies of Purified Rat TRPV1Martinez, Gilbert Q. / Raza, Marium M. / Gordon, Sharona E. et al. | 2019
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Re-Education of Tumor Associated Macrophages by TrabectedinPeraza, Diego A. / Garcia-Redondo, Ana B. / Povo-Retana, Adrian / Arias, Sara / Briones, Ana M. / Boscá, Lisardo / Galmarini, Carlos M. / Valenzuela, Carmen et al. | 2019
- 541a
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Proteomics Analysis Points at Novel Cellular Partners for the KCNMB1 Protein ProductNorth, Kelsey / Kakhniashvili, David / Dopico, Alex M. / Bukiya, Anna N. et al. | 2019
- 542a
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CP1 Is a Potent IKs Channel Activator Which Acts by Substituting Phosphatidylinositol 4, 5 BisphosphateLiu, Yongfeng / Xu, Xianjin / Naffaa, Moawiah M. / Liang, Hongwu / Zhang, Guohui / Hou, Panpan / Wang, Hongzhan / Gao, Junyuan / Shi, Jingyi / Cohen, Ira et al. | 2019
- 543a
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Conserved Residues at the Interface between the S4 and S5 Segments are Critical for Normal Gating of HCN ChannelsRamentol, Rosamary / Perez, Marta E. / Larsson, H. Peter et al. | 2019
- 547a
-
Physical Model for Cell Migration Guided by Elastic Properties of the SubstrateMárquez, Susana / Soto, Rodrigo / Concha, Miguel / Reig, German et al. | 2019
- 548a
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Cellular Traction Forces and Locations of Adhesion Site Regulate Cell FunctionsWala, Jyoti / Das, Soumen et al. | 2019
- 549a
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Novel Method of Determining Cellular Traction Forces during EMTGriffin, Brian P. / Lemmon, Christopher A. et al. | 2019
- 550a
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Probing Fluctuations and Avalanches in the Cytoskeleton with Active Micropost ArraysShi, Yu / Reich, Daniel H. / Porter, Christopher L. / Crocker, John C. et al. | 2019
- 551a
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Elucidating Steps in Actin Polymerization and Nucleation using a Coarse-Grained Model of Multiprotein Complex FormationHoran, Brandon G. / Vavylonis, Dimitrios / Mittal, Jeetain et al. | 2019
- 552a
-
Substrate Binding and Conformational Changes of the Bile Acid Symporter ASBTNMNaughton, Fiona B. / Becker, Patrick / Brotherton, Deborah / Cameron, Alexander D. / Beckstein, Oliver et al. | 2019
- 553a
-
Atypical RCK Domain Present in a Two Component K+/H+ AntiporterCereija, Tatiana / Pedro, Joao / Guerra, Leitao / Morais Cabral, Joao H. et al. | 2019
- 554a
-
Molecular Basis for Ion Recognition and Transport in a Na+/Ca2+ ExchangerMarinelli, Fabrizio / Ficici, Emel / Faraldo-Gómez, Jose' D. et al. | 2019
- 555a
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Direct Protein-Lipid Interactions Shape the Conformational Landscape of Secondary TransportersMartens, Chloe / Shekhar, Mrinal / Borysik, Antoni / Lau, Andy / Reading, Eamonn / Tajkhorshid, Emad / Booth, Paula / Politis, Argyris et al. | 2019
- 556a
-
Evolution of Ion Specificity in Glutamate TransportersReddy, Krishna / Boudker, Olga et al. | 2019
- 557a
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Identifying Structural Determinants of High-Potency MDPV Binding at the Human Dopamine Transporter S1 Binding SiteSteele, Tyler W.E. / Ruiz, Brian / Spires, Zachary / Eltit, Jose M. et al. | 2019
- 559a
-
In Silico Experiments as a Method to Compare Transportes MechanismSánchez, Yuly E. / Aguilar, Julian et al. | 2019
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Integrated Computational Model of Lung Tissue BioenergeticsZhang, Xiao / Dash, Ranjan K. / Clough, Anne / Xie, Dexuan / Jacobs, Elizabeth / Audi, Said et al. | 2019
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New Method to Determine the Effect of Dimerization on Protein Flexibility from Molecular Dynamics Simulation using Structural HierarchyChakravorty, Arghya / Higham, Jonathan / Alexov, Emil / Henchman, Richard H. et al. | 2019
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-
Dynamical Network Analysis of Protein:RNA Complexes Made Easydos Reis Melo, Marcelo Cardoso / Bernardi, Rafael C. / Luthey-Schulten, Zaida et al. | 2019
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Automation of a Laser Tweezers Raman Spectroscopy Apparatus for Biological InvestigationsScott, Nathaniel W. / Hancock, Scott / Hester, Brooke C. / Burris, Jennifer L. et al. | 2019
- 567a
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Spectral Phasor Analysis on Nanosecond-Gated Autofluorescence Reveals Real Time Information on Cellular NAD(P)H Conformation during Chemically-Induced Metabolic ResponseUrayama, Paul K. / Short, Audrey / Heidelman, Martin / Kreider, Max / Rodriguez, Andrew I. / Kai Wong, Chong / Al Aayedi, Nazar / Cai, Zhifan et al. | 2019
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Fluorophore-Induced Plasmonic CurrentMoskowitz, Josh / Geddes, Christopher D. et al. | 2019
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GPU Accelerated Computation of Isotropic Chemical Shifts Offers New Dimension of Structure Refinement in Largescale Molecular Dynamics SimulationBryer, Alexander J. / Wright, Eric F. / Ferrato, Mauricio / Huber, Thomas / Ortiz, Edwin / Searles, Robert / Chandrasekaran, Sunita / Perilla, Juan R. et al. | 2019
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Single Particle Cryo-EM Workflow: Structures of Apoferritin and AldolaseBobe, Daija / Rice, William J. / Eng, Edward T. / Kim, Laura Y. / Kopylov, Mykhailo / Raczkowski, Ashleigh M. / Carragher, Bridget / Potter, Clinton S. et al. | 2019
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Investigating the Structural Mechanism of the Stalled Bacterial Ribosome Bound to a Drug that Targets Trans-TranslationMehrani, Atousa / Hoffer, Eric D. / Goralski, Tyler D.P. / Keiler, Kenneth C. / Dunham, Christine M. / Stagg, Scott et al. | 2019
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The Structural Basis for Release Factor Activation during Translation Termination Revealed by Time-Resolved Cryogenic Electron MicroscopyFu, Ziao / Indrisiunaite, Gabriele / Kaledhonkar, Sandip / Shah, Binita / Sun, Ming / Chen, Bo / Grassucci, Robert A. / Ehrenberg, Mans / Frank, Joachim et al. | 2019
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Ultrasound-Mediated Targeted Drug Delivery in T-CellsKarki, Alina / Giddings, Emily / Rincon, Mercedes / Wu, Junru et al. | 2019
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Engineering a Coiled Coil Protein as pH SensorHashmi, Ameed / Sadqi, Mourad / Muñoz, Victor et al. | 2019
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Should Virus Capsids Assemble Perfectly? A Simple Equilibrium Model for DefectsSpiriti, Justin M. / Conway, James F. / Zuckerman, Daniel M. et al. | 2019
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Probing Structure, Topology and Dynamics of KCNE3 in Proteoliposomes using Site-Direct Spin Labeling and EPR SpectroscopyDhilhani Mohammed Faleel, Fathima / Sahu, Indra D. / McCarrick, Robert M. / Sanders, Charles R. / Lorigan, Gary A. et al. | 2019
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Probing the Active and Inactive Forms of the Bacteriophage S21 Pinholin Protein System using Magnetic Resonance SpectroscopyDrew, Daniel L. / Ahammad, Tanbir / Serafin, Rachel / Butcher, Brandon / Clowes, Katherine / Sahu, Indra D. / McMarrick, Robert / Lorigan, Gary A. et al. | 2019
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Elucidation of the Role of the Interaction between RecQ Helicase and SSB ProteinHarami, Gabor M. / Mills, K. Maria / Kovacs, Zoltan J. / Seol, Yeonee / Barath, Veronika / Nemeth, Julianna B. / Harami-Papp, Hajnalka / Neuman, Keir C. / Kovacs, Mihaly et al. | 2019
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Novel Assay Resolves D-Loop Processing Pathways by E. Coli RecQ and Human BLM HelicasesHarami, Gabor M. / Palinkas, Janos / Seol, Yeonee / Gyimesi, Mate / Kovacs, Zoltan J. / Neuman, Keir C. / Kovacs, Mihaly et al. | 2019
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Effects of Cholesterol on Fengycin, an Antimicrobial Lipopeptide Using Weighted Ensemble Path Sampling MethodSur, Sreyoshi / Grossfield, Alan et al. | 2019
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Effect of Real-Time Leak Current Correction on Action Potentials Recorded from Induced Pluripotent Stem Cell-Derived Cardiac MyocytesPanama, Brian / Nowak, Mark / Franks, Brandon / Korbel, Leigh / Bett, Glenna / Rasmusson, Randall et al. | 2019
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Protein-Water and Solvent-Mediated Interactions in Multi-Scale SimulationsHeyden, Matthias et al. | 2019
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Cusp Artifacts in High Order Superresolution Optical Fluctuation Imaging (SOFI)Yi, Xiyu / Weiss, Shimon et al. | 2019
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Novel Morphological and Functional Insights in Python Cardiac BiologyCrocini, Claudia / Woulfe, Kathleen C. / Leinwand, Leslie A. et al. | 2019
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Molecular Simulations Give Insights into the NDM-1/Membrane Interaction that Causes Rise of a Super-BacteriumPrunotto, Alessio / Bahr, Guillermo / González, Lisandro / Vila, Alejandro / Dal Peraro, Matteo et al. | 2019
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Observation of Allosteric Signaling through DNA with Single-Molecule FRET and Cryo-EMRosenblum, Gabriel / Elad, Nadav / Wiggers, Felix / Hofmann, Hagen et al. | 2019
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Tracking of Labeled Motor Domains of Single Full-Length Myosin X on Actin BundlesQin, Xianan / Man Cheng, Harry Chun / Li, Jing / Yoo, Hanna / Liu, Xiaoyan / Lin, Tianming / Sweeney, H. Lee / Park, Hyokeun et al. | 2019
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Optical Control of Fast and Processive Engineered Myosins In Vitro and in Living CellsRuijgrok, Paul V. / Ghosh, Rajarshi P. / Nakamura, Muneaki / Zemsky, Sasha / Chen, Robert / Vachharajani, Vipul / Liphardt, Jan T. / Bryant, Zev et al. | 2019
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CRISPR/Cas9 Engineered Q3925E-RyR2 Mutation in Human Induced Pluripotent Stem Cells Impairs Caffeine Triggered Ca2+ ReleaseZhang, Xiaohua / Wei, Hua / Yamaguchi, Naohiro / Morad, Martin et al. | 2019
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Computational and Experimental Investigation of Cardiac Troponin T R173Q, R173W and Δ160E Mutation Specific Correlates to DiseaseDeranek, Andrea E. / Baldo, Anthony / Schwartz, Steven / Tardiff, Jil C. et al. | 2019
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Mechanism of Cholesterol Sensing in the Niemann Pick Protein (NPC1) using Molecular Dynamics SimulationsDubey, Vikas / Bozorg, Behruz / Wüstner, Daniel / Khandelia, Himanshu et al. | 2019
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Cholesterol Affects the Bending Rigidity of DOPC MembranesAshkar, Rana / Doktorova, Milka / Heberle, Frederick A. / Scott, Haden / Kelley, Elizabeth / Nagao, Michihiro / Usery, Rebecca / Barrera, Francisco N. / Feigenson, Gerald W. / Katsaras, John et al. | 2019
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Allosteric Effects and Signal Transduction in the Peptide-MHC Binding to a Human T Cell ReceptorMa, Buyong / Orban, John P. / Mariuzza, Roy / Nussinov, Ruth et al. | 2019
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DNA Thermal Stability Depends on Solution ViscosityStellwagen, Nancy C. / Stellwagen, Earle et al. | 2019
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Constant pH Study of a Sodium ChannelDamjanovic, Ana / Chen, Ada Y. / Rosenberg, Robert L. / Roe, Daniel / Brooks, Bernard R. et al. | 2019
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Fluorescently Labelled Myosin Regulatory Light Chains as Biosensors for Thick Filament Activation in Heart MuscleParijat, Priyanka / Irving, Malcolm / Kampourakis, Thomas et al. | 2019
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Protein Partitioning to Lipid Domains in All-Atom MD SimulationPantelopulos, George A. / Bandara, Asanga / Straub, John E. et al. | 2019
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Time-Resolved X-Ray Studies of Skeletal Muscle from a Duchene Muscular Dystrophy Rat ModelYuan, Chen-Ching / Powers, Joseph D. / Murray, Jason / Mohran, Saffie / Ma, Weikang / Luttrell, Shawn M. / Irving, Thomas C. / Regnier, Michael / Mack, David L. et al. | 2019
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Structure Function Studies of a Plant Non Selective Cation Channel Involved in Drough ToleranceKrishnan, Srinivasan / Maity, Koustav / McGrath, Aaron P. / Kochian, Leon / Chang, Geoffrey / Piñeros, Miguel et al. | 2019
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Cell Fate Decision by an Adaptable Molecular Timer of P53Zhang, Xiaopeng et al. | 2019
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Utilizing Umbrella Sampling and Brownian Dynamics to Study the Functional and Dynamic Characteristics of Cardiac Troponin CBowman, Jacob D. / Lindert, Steffen et al. | 2019
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Transient Increases in Mouse Brain Water Activity Deduced from Hydration/Dehydration Rates Ex VivoMcGee, Maria P. / Morykwas, Michael / Argenta, Louis et al. | 2019
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Early Translocation of Anthrax Lethal Factor: Kinetics from Molecular Dynamics Simulations and Milestoning TheoryMa, Piao / Cardenas, Alfredo E. / Chaudhari, Mangesh / Elber, Ron / Rempe, Susan L. et al. | 2019
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Evaluation and Optimization of Novel Formulations for Delivery of Hydrophilic Biological Drugs using Biocompatible SurfactantsWork, Hannah M. / Iovine, Joseph C. / Webber, Nakoa K. / Douglas, Taylor V. / Ricci, Samuel L. / Calhoun, Ryan P. / Baker, Gabriela V. / Richards, Elizabeth A. / Yang, Daniel D. / Carone, Benjamin R. et al. | 2019
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Breadth of Human Monoclonal Antibodies Isolated from RTS, S/AS01 Vaccinees Binding to Plasmodium falciparum Circumsporozoite Protein AntigensDennison, S. Moses / Abraha, Milite / Huntwork, Richard H.C. / Li, Kan / Mauldin, Dustin L. / Alam, S. Munir / Tomaras, Georgia D. et al. | 2019
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Molecular Insight into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-HT3A ReceptorsKate Ladefoged, Lucy / Munro, Lachlan / Kristensen, Anders S. / Schiøtt, Birgit et al. | 2019
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Advances in the Structural and Biochemical Determination of Several Dynamin-Like GTPasesKehr, Andrew D. / Meng, Shuxia / Martin, Matthew F. / Chan, David / Hinshaw, Jenny E. et al. | 2019
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Mechanobiological Control of the Immune ResponseColin-York, Huw / Javanmardi, Yousef / Moeendarbary, Emad / Eggeling, Christian / Fritzsche, Marco et al. | 2019
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Uptake Dynamics in the Lactose Permease (LacY) Membrane Protein TransporterKimanius, Dari / Lindahl, Erik R. / Andersson, Magnus et al. | 2019
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Hunting for the Adhesion Molecule, Retinoschisin, in Retina using CemovisHeymann, Bernard / Bleck, Christopher K.E. / Fariss, Robert N. / Smirnov, Alexandr / Winkler, Dennis C. / Vijayasarathy, Camasamudram / Huang, Rick / Dearborn, Altaira D. / Sieving, Paul A. / Steven, Alasdair C. et al. | 2019
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FRET at the Single Molecule Level using Molecular Brightness and Fluorescence Correlation SpectroscopyMiller, Robert C. / Simonet, Rowan / Libal, Christin / Aplin, Cody / Cong, Anh / Gurumani, Margaret / Kauffman, Emma / Bok Lee, Hong / Boersma, Arnold J. / Sheets, Erin D. et al. | 2019
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Rotational and Translational Diffusion in Concentrated Ficoll SolutionsJhamba, Elton / Boukari, Hacene et al. | 2019
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Network-Based Modeling of Amyloid Fibril FormationGrazioli, Gianmarc / Yu, Yue / Unhelkar, Megha H. / Martin, Rachel W. / Butts, Carter T. et al. | 2019
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Junctional Forces Maintain Isometric Tension of the Epithelial MonolayerScott, Lewis E. / Lemmon, Christopher A. / Weinberg, Seth H. et al. | 2019
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Quantitative Mass Imaging of Actin NucleationHundt, Nikolas / Young, Gavin / Cole, Daniel / Hantke, Max / Kukura, Philipp et al. | 2019
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Thermotaxis Involves Spontaneous Backward Swimming in ChlamydomonasSekiguchi, Masaya / Kameda, Shigetoshi / Kurosawa, Satoshi / Yoshida, Megumi / Yoshimura, Kenjiro et al. | 2019
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Mechanism of BK Channel Inhibition by the Opioid Agonist LoperamideVouga, Alexandre G. / Rockman, Michael E. / Jacobson, Marlene A. / Rothberg, Brad S. et al. | 2019
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IPMK Loss Inhibits Cellular Motility and ContractilityPadhi, Abinash / Tu-Sekine, Becky / Apperson, Matthew / Jin, Sunghee / Nain, Amrinder S. / Kim, Sangwon F. et al. | 2019
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Cell Response to Liquid Crystal OrderEndresen, Kirsten D. / Serra, Francesca / Lepori, Michael A. et al. | 2019
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Identifying Common Structural Features for Electromechanical Coupling between Domain-Swapped and Non-Domain Swapped Potassium ChannelsFernández-Mariño, Ana I. / Swartz, Kenton J. et al. | 2019
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Mechanical Responses of Cancer Cells to Different Matrices Measured by AFM and FRETTian, Fang / Lin, Tsung-Cheng / Wang, Liang / Chen, Sidong / Chu, Jun / Kiang, Ching-Hwa / Park, Hyokeun et al. | 2019
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Extracellular zinc Contributes to the Slow Polyspermy BlockWozniak, Katherine L. / Phelps, Wesley A. / Lee, Miler T. / Carlson, Anne E. et al. | 2019
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Calcium Dependence, Kinetics, and Pore Dynamics of Physiological Vesicle Fusion with Planar Supported BilayersKreutzberger, Alex J.B. / Kiesling, Volker / Liang, Binyong / Seelheim, Patrick / Anantharam, Arun / Castle, J. David / Tamm, Lukas K. et al. | 2019
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Distinct Roles of Snare-Mimicking Lipopeptides during Initial Steps of Membrane FusionKros, Alexander et al. | 2019
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The Serotonin Transporter Modulates the Quantal Size of Vesicular Release Events in Adrenal Chromaffin CellsBrindley, Rebecca L. / Currie, Kevin P. et al. | 2019
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Lipid Membrane Influences Interaction between the C1 Domain of Munc13-1 and the ActivatorYou, Youngki / Yu, Binhan / Igumenova, Tatyana / Das, Joydip et al. | 2019
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Partitioning of Vibrio Cholerae Autoinducer Cai1 and its Precursors into Lipid Membranes Suggests the Direct Release MechanismCetuk, Hannah et al. | 2019
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Comparing Early Stages of Amyloid-Beta Aggregation in Different Membranous EnvironmentsSahoo, Abhilash / Xu, Hongcheng / Matysiak, Silvina et al. | 2019
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Structural Optimization of α-Synuclein Fibril Growth InhibitorsAfitska, Kseniia / Shvadchak, Volodymyr V. / Yushchenko, Dmytro A. et al. | 2019
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Micro-Second X-Ray Single Molecule Dynamics of Allosteric Twisting Motions in HemoglobinSasaki, Yuji C. / Kuramochi, Masahiro / Okamura, Yuu / Sekiguchi, Hiroshi / Yamamoto, Naoki / Shibayama, Naoya et al. | 2019
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Tight Binding of Natural Polyphenols to the Intrinsically Disordered Mammalian High Mobility Group Protein At-Hook 2Su, Linjia / Chambers, Jeremy / Leng, Fenfei et al. | 2019
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Proteins' Dynamics, Hydration and Conformational Changes Studied by EPRBordignon, Enrica et al. | 2019
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Dynamics of the Protein Interfaces of the Ebola Virus VP40 Structural Matrix FilamentPavadai, Elumalai / Bhattarai, Nisha / Chapagain, Prem P. / Gerstman, Bernard S. et al. | 2019
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Temperature Dependence of the Protein-Chromophore Hydrogen Bond Dynamics in the Far-Red Fluorescent Proteins mNeptune1, mNeptune2.5 and mCardinal2Dhakal, Chandra / Chapagain, Prem / Wang, Xuewen et al. | 2019
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Using Histone H1 Derived Peptides to Investigate Binding Affinity and Inter-Domain Dynamics in Human Pin1Jinasena, Dinusha / Bowleg, Jerrano / Simmons, Robert / Zhang, Yue / Gwaltney, Steven R. / Fitzkee, Nicholas C. et al. | 2019
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PH-Driven Conformational Reorganization of Proteins: NMR Spectroscopy Study with Buried Lys ResiduesKougentakis, Christos M. / Majumdar, Ananya / Schlessman, Jamie L. / Garcia-Moreno, Bertrand et al. | 2019
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Effect of Resultant Dipole Moment on Mechanical Stability of Protein-Peptide ComplexesKouza, Maksim / Banerji, Anirban / Kolinski, Andrzej / Buhimschi, Irina / Kloczkowski, Andrzej et al. | 2019
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Photonic Platform for Detailed Physical Characterization of Liquid Protein DropletsCojoc, Gheorghe / Beck, Timon / Ahmed, Saeed / Franzmann, Titus / Müller, Paul / Schürmann, Mirjam / Schlüβler, Raimund / Kim, Kyoohyun / Fischer-Friedrich, Elisabeth / Alberti, Simon et al. | 2019
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Superresolution Imaging of Amyloid Structures over Extended Times using Transient Binding of Single Thioflavin T MoleculesSpehar, Kevin / Ding, Tianben / Sun, Yuanzi / Kedia, Niraja / Lu, Jin / Nahass, George R. / Lew, Matthew D. / Bieschke, Jan et al. | 2019
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Copy Number and Function of Individual Disordered Proteins in the Nuclear Pore Complex Revealed by Combining Auxin-Inducible Degron Strategy and High-Speed Single -Molecule MicroscopyLi, Yichen / Aksenova, Vasilisa / Yu, Jingjie / Ma, Ping / Arnaoutov, Alexei / Dasso, Mary / Yang, Weidong et al. | 2019
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Capturing the Mechanism Underlying Top-Binding to the LARP1 DM15 RegionCassidy, Kevin C. / Lahr, Roni M. / Kaminsky, Jesse C. / Berman, Andrea J. / Durrant, Jacob D. et al. | 2019
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Comparative Molecular Dynamics Dynamics of the BRAF Activation Loop Reveals a Biophysical Mechanism of Cancer Recurrence Under Drug InhibitionBabbitt, Gregory A. / Hudson, Andre / Adams, Lily et al. | 2019
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Changes in Secondary Structure of Human Prion Protein Peptide 30-90 under the Influence of Selected Dicationic and Anionic SurfactantsLudwiczak, Julia / Kozak, Maciej / Szutkowski, Kosma / Zhukov, Igor et al. | 2019
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Making Swaps Until Activity Drops - Localizing the Different Specific Activity of Presenilin Homologues to Protein DomainsSchmidt, Fabian C. / Steiner, Harald / Langosch, Dieter et al. | 2019
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Invadopodia Dynamics is Regulated by ECM Cross-LinkingEsmaeili Pourfarhangi, Kamyar / Bergman, Aviv / Gligorijevic, Bojana et al. | 2019
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The Steady State Concentration of Different Biomarkers of Oxidative Stress Reflect Different Types of Oxidative StressLichtenberg, Dov A. / Pinchuk, Ilya / Grune, Tilman / Weber, Daniela et al. | 2019
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Effects of PTEN Loss and Activated KRAS Overexpression on Viscoelasticity of Breast Epithelial CellsLinthicum, Will / Ho Thanh, Minh-Tri / Vitolo, Michele I. / Wen, Qi et al. | 2019
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Unravelling the Role of Electrostatics in Regulating the Processivity of Cytoplasmic Dynein at Single Molecule LevelPabbathi, Ashok / Lovelace, Hailey / Alper, Joshua et al. | 2019
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Iocbio Sparks Detection and Analysis SoftwareLaasmaa, Martin / Karro, Niina / Birkedal, Rikke / Vendelin, Marko et al. | 2019
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Force Loading During Mechanosensing Emerges from Non-Mechanosensitive Active DisplacementsFeld, Lea / Livne, Ariel / Lubomirsky, Yuri / Mukherjee, Abhishek / Bouchbinder, Eran / Wolfenson, Haguy et al. | 2019