Multifunctional Molecular Therapeutic Agent for Targeted and Controlled Dual Chemo- and Photodynamic Therapy (Unknown)
- New search for: Ha, Summer Y. Y.
- New search for: Zhou, Yimin
- Further information on Zhou, Yimin:
- https://orcid.org/0000-0002-9683-5955
- New search for: Fong, Wing-Ping
- Further information on Fong, Wing-Ping:
- https://orcid.org/0000-0002-0468-9883
- New search for: Ng, Dennis K. P.
- Further information on Ng, Dennis K. P.:
- https://orcid.org/0000-0001-9087-960X
- New search for: Ha, Summer Y. Y.
- New search for: Zhou, Yimin
- Further information on Zhou, Yimin:
- https://orcid.org/0000-0002-9683-5955
- New search for: Fong, Wing-Ping
- Further information on Fong, Wing-Ping:
- https://orcid.org/0000-0002-0468-9883
- New search for: Ng, Dennis K. P.
- Further information on Ng, Dennis K. P.:
- https://orcid.org/0000-0001-9087-960X
In:
Journal of Medicinal Chemistry
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63
, 15
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8512-8523
;
2020
- Article (Journal) / Electronic Resource
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Title:Multifunctional Molecular Therapeutic Agent for Targeted and Controlled Dual Chemo- and Photodynamic Therapy
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Additional title:J. Med. Chem.
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Contributors:Ha, Summer Y. Y. ( author ) / Zhou, Yimin ( author ) / Fong, Wing-Ping ( author ) / Ng, Dennis K. P. ( author )
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Published in:Journal of Medicinal Chemistry ; 63, 15 ; 8512-8523
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Publisher:
- New search for: American Chemical Society
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Publication date:2020-08-13
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Source:
Table of contents – Volume 63, Issue 15
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 7921
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New Horizons in Drug Discovery - Understanding and Advancing Kinase InhibitorsLaufer, Stefan / Briner, Karin / Bajorath, Jürgen / Georg, Gunda I. / Wang, Shaomeng et al. | 2020
- 7923
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Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic ResistanceCascioferro, Stella / Parrino, Barbara / Carbone, Daniela / Schillaci, Domenico / Giovannetti, Elisa / Cirrincione, Girolamo / Diana, Patrizia et al. | 2020
- 7957
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Medicinal Chemistry of Inhibiting RING-Type E3 Ubiquitin LigasesBlaquiere, Nicole / Villemure, Elisia / Staben, Steven T. et al. | 2020
- 7986
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Emerging Substrate Proteins of Kelch-like ECH Associated Protein 1 (Keap1) and Potential Challenges for the Development of Small-Molecule Inhibitors of the Keap1-Nuclear Factor Erythroid 2‑Related Factor 2 (Nrf2) Protein–Protein InteractionZhang, Yong / Shi, Zeyu / Zhou, Yujun / Xiao, Qiong / Wang, Hongyue / Peng, Ying et al. | 2020
- 8003
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4D-Printed Dynamic Materials in Biomedical Applications: Chemistry, Challenges, and Their Future Perspectives in the Clinical SectorZhou, Wenxian / Qiao, Zhiguang / Nazarzadeh Zare, Ehsan / Huang, Jinfeng / Zheng, Xuanqi / Sun, Xiaolei / Shao, Minmin / Wang, Hui / Wang, Xiaoyan / Chen, Dong et al. | 2020
- 8025
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Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 KinaseSchulze, Volker K. / Klar, Ulrich / Kosemund, Dirk / Wengner, Antje M. / Siemeister, Gerhard / Stöckigt, Detlef / Neuhaus, Roland / Lienau, Philip / Bader, Benjamin / Prechtl, Stefan et al. | 2020
- 8043
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JNJ-5371678, Defining a Role for Fusion Inhibitors in the Treatment of Respiratory Syncytial VirusCockerill, G. Stuart et al. | 2020
- 8046
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Discovery of 3‑({5-Chloro-1-[3-(methylsulfonyl)propyl]‑1H‑indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro‑2H‑imidazo[4,5‑c]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial VirusVendeville, Sandrine / Tahri, Abdellah / Hu, Lili / Demin, Samuel / Cooymans, Ludwig / Vos, Ann / Kwanten, Leen / Van den Berg, Joke / Battles, Michael B. / McLellan, Jason S. et al. | 2020
- 8059
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Metabolic Activation of Pirfenidone Mediated by Cytochrome P450s and SulfotransferasesZhou, Shenzhi / Li, Wei / Tian, Min / Zhang, Na / Yang, Xiaojing / Li, Weiwei / Peng, Ying / Zheng, Jiang et al. | 2020
- 8069
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β‑Hydroxy- and β‑Aminophosphonate Acyclonucleosides as Potent Inhibitors of Plasmodium falciparum GrowthCheviet, Thomas / Wein, Sharon / Bourchenin, Gabriel / Lagacherie, Manon / Périgaud, Christian / Cerdan, Rachel / Peyrottes, Suzanne et al. | 2020
- 8088
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Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family ApproachLorthiois, Edwige / Roache, James / Barnes-Seeman, David / Altmann, Eva / Hassiepen, Ulrich / Turner, Gordon / Duvadie, Rohit / Hornak, Viktor / Karki, Rajeshri G. / Schiering, Nikolaus et al. | 2020
- 8114
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Structure–Activity Relationship Studies of Retro‑1 Analogues against Shiga ToxinAbdelkafi, Hajer / Michau, Aurélien / Pons, Valérie / Ngadjeua, Flora / Clerget, Alexandra / Ait Ouarab, Lilia / Buisson, David-Alexandre / Montoir, David / Caramelle, Lucie / Gillet, Daniel et al. | 2020
- 8134
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Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid InhibitorsChen, Wuhong / Liu, Feifei / Zhao, Qiliang / Ma, Xinna / Lu, Dong / Li, Heng / Zeng, Yanping / Tong, Xiankun / Zeng, Limin / Liu, Jia et al. | 2020
- 8146
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Discovery of an Orally Active Small-Molecule Tumor Necrosis Factor‑α InhibitorSun, Weiguang / Wu, Yanli / Zheng, Mengzhu / Yang, Yueying / Liu, Yang / Wu, Canrong / Zhou, Yirong / Zhang, Yonghui / Chen, Lixia / Li, Hua et al. | 2020
- 8157
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Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast CancerYao, Hong / Xie, Shaowen / Ma, Xiaoqian / Liu, Junkai / Wu, Hongyu / Lin, Aijun / Yao, Hequan / Li, Dahong / Xu, Shengtao / Yang, Dong-Hua et al. | 2020
- 8179
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A New Class of Dengue and West Nile Virus Protease Inhibitors with Submicromolar Activity in Reporter Gene DENV‑2 Protease and Viral Replication AssaysKühl, Nikos / Graf, Dominik / Bock, Josephine / Behnam, Mira A. M. / Leuthold, Mila-Mareen / Klein, Christian D. et al. | 2020
- 8198
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Oligopeptides as Neuropeptide Y Y4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide AntagonistKonieczny, Adam / Braun, Diana / Wifling, David / Bernhardt, Günther / Keller, Max et al. | 2020
- 8216
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Generation of Leads for γ‑Secretase ModulationMandal, Mihirbaran / Buevich, Alexei / Caldwell, John P. / Hyde, Lynn / Huang, Xianhai / Liu, Xiaoxiang / McKittrick, Brian / Mazzola, Robert D. / Pissarnitski, Dmitri / Palani, Anandan et al. | 2020
- 8231
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Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter SialinDubois, Lilian / Pietrancosta, Nicolas / Cabaye, Alexandre / Fanget, Isabelle / Debacker, Cécile / Gilormini, Pierre-André / Dansette, Patrick M. / Dairou, Julien / Biot, Christophe / Froissart, Roseline et al. | 2020
- 8250
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A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor AgonistsReynaud, Steve / Ciolek, Justyna / Degueldre, Michel / Saez, Natalie J. / Sequeira, Ana Filipa / Duhoo, Yoan / Brás, Joana L. A. / Meudal, Hervé / Cabo Díez, Miguel / Fernández Pedrosa, Victoria et al. | 2020
- 8265
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Imaging Biotin Trafficking In Vivo with Positron Emission TomographyBongarzone, Salvatore / Sementa, Teresa / Dunn, Joel / Bordoloi, Jayanta / Sunassee, Kavitha / Blower, Philip J. / Gee, Antony et al. | 2020
- 8276
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Target-Based Identification and Optimization of 5‑Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition AssayKnoepfel, Thomas / Nimsgern, Pierre / Jacquier, Sébastien / Bourrel, Marjorie / Vangrevelinghe, Eric / Glatthar, Ralf / Behnke, Dirk / Alper, Phil B. / Michellys, Pierre-Yves / Deane, Jonathan et al. | 2020
- 8296
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Structural Analysis of Potent Hybrid HIV‑1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide IsostereRusere, Linah N. / Lockbaum, Gordon J. / Henes, Mina / Lee, Sook-Kyung / Spielvogel, Ean / Rao, Desaboini Nageswara / Kosovrasti, Klajdi / Nalivaika, Ellen A. / Swanstrom, Ronald / Kurt Yilmaz, Nese et al. | 2020
- 8314
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The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate ReductaseDuff, Michael R. / Gabel, Scott A. / Pedersen, Lars C. / DeRose, Eugene F. / Krahn, Juno M. / Howell, Elizabeth E. / London, Robert E. et al. | 2020
- 8325
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Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based MethodsSarkar, Dhruba / Olejniczak, Edward T. / Phan, Jason / Coker, Jesse A. / Sai, Jiqing / Arnold, Allison / Beesetty, Yugandhar / Waterson, Alex G. / Fesik, Stephen W. et al. | 2020
- 8338
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Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death–Ligand 1 Interaction as Potential Anticancer AgentsCheng, Binbin / Ren, Yichang / Niu, Xiaoge / Wang, Wei / Wang, Shuanghu / Tu, Yingfeng / Liu, Shuwen / Wang, Jin / Yang, Deying / Liao, Guochao et al. | 2020
- 8359
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N‑Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium CollagenasesKonstantinović, Jelena / Yahiaoui, Samir / Alhayek, Alaa / Haupenthal, Jörg / Schönauer, Esther / Andreas, Anastasia / Kany, Andreas M. / Müller, Rolf / Koehnke, Jesko / Berger, Fabian K. et al. | 2020
- 8369
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Design and Structural Optimization of Dual FXR/PPARδ ActivatorsSchierle, Simone / Neumann, Sebastian / Heitel, Pascal / Willems, Sabine / Kaiser, Astrid / Pollinger, Julius / Merk, Daniel et al. | 2020
- 8380
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Development of Conformationally Constrained α‑RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine ReceptorsZheng, Nan / Christensen, Sean B. / Blakely, Alan / Dowell, Cheryl / Purushottam, Landa / McIntosh, J. Michael / Chou, Danny Hung-Chieh et al. | 2020
- 8388
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Discovery and Characterization of Pure RhlR Antagonists against Pseudomonas aeruginosa InfectionsNam, SangJin / Ham, So-Young / Kwon, Hongmok / Kim, Han-Shin / Moon, Suhyun / Lee, Jeong-Hoon / Lim, Taehyeong / Son, Sang-Hyun / Park, Hee-Deung / Byun, Youngjoo et al. | 2020
- 8408
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The Most Common Functional Groups in Bioactive Molecules and How Their Popularity Has Evolved over TimeErtl, Peter / Altmann, Eva / McKenna, Jeffrey M. et al. | 2020
- 8419
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Probing the Plasticity in the Active Site of Protein N‑terminal Methyltransferase 1 Using Bisubstrate AnaloguesChen, Dongxing / Dong, Cheng / Dong, Guangping / Srinivasan, Karthik / Min, Jinrong / Noinaj, Nicholas / Huang, Rong et al. | 2020
- 8432
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Characterization of TnmH as an O‑Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody–Tiancimycin ConjugatesAdhikari, Ajeeth / Teijaro, Christiana N. / Yan, Xiaohui / Chang, Chin-Yuan / Gui, Chun / Liu, Yu-Chen / Crnovcic, Ivana / Yang, Dong / Annaval, Thibault / Rader, Christoph et al. | 2020
- 8442
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Tideglusib and Its Analogues As Inhibitors of Staphylococcus aureus SrtAYang, Teng / Zhang, Tao / Guan, Xiang-Na / Dong, Ze / Lan, Lefu / Yang, Song / Yang, Cai-Guang et al. | 2020
- 8458
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Photoswitchable Antagonists for a Precise Spatiotemporal Control of β2‑AdrenoceptorsDuran-Corbera, Anna / Catena, Juanlo / Otero-Viñas, Marta / Llebaria, Amadeu / Rovira, Xavier et al. | 2020
- 8471
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Targeted Delivery of Antisense Oligonucleotides Using Neurotensin PeptidesNikan, Mehran / Tanowitz, Michael / Dwyer, Chrissa A. / Jackson, Michaela / Gaus, Hans J. / Swayze, Eric E. / Rigo, Frank / Seth, Punit P. / Prakash, Thazha P. et al. | 2020
- 8485
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Structure of Human Phosphodiesterase 5A1 Complexed with Avanafil Reveals Molecular Basis of Isoform Selectivity and Guidelines for Targeting α‑Helix Backbone Oxygen by Halogen BondingHsieh, Chao-Ming / Chen, Chun-Yi / Chern, Ji-Wang / Chan, Nei-Li et al. | 2020
- 8495
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Structural Basis of Noscapine Activation for Tubulin BindingOliva, María A. / Prota, Andrea E. / Rodríguez-Salarichs, Javier / Bennani, Youssef L. / Jiménez-Barbero, Jesús / Bargsten, Katja / Canales, Ángeles / Steinmetz, Michel O. / Díaz, J. Fernando et al. | 2020
- 8502
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Structural Basis of AZD9291 Selectivity for EGFR T790MYan, Xiao-E / Ayaz, Pelin / Zhu, Su-Jie / Zhao, Peng / Liang, Ling / Zhang, Casey H. / Wu, Ya-Chuang / Li, Je-Luen / Choi, Hwan Geun / Huang, Xin et al. | 2020
- 8512
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Multifunctional Molecular Therapeutic Agent for Targeted and Controlled Dual Chemo- and Photodynamic TherapyHa, Summer Y. Y. / Zhou, Yimin / Fong, Wing-Ping / Ng, Dennis K. P. et al. | 2020
- 8524
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Amplified Detection of Breast Cancer Autoantibodies Using MUC1-Based Tn Antigen MimicsGuillen-Poza, Pablo A. / Sánchez-Fernández, Elena M. / Artigas, Gerard / García Fernández, José Manuel / Hinou, Hiroshi / Ortiz Mellet, Carmen / Nishimura, Shin-Ichiro / Garcia-Martin, Fayna et al. | 2020
- 8534
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Stepwise Design of γ‑Secretase Modulators with an Advanced Profile by Judicious Coordinated Structural Replacements and an Unconventional Phenyl Ring BioisostereRodríguez Sarmiento, Rosa María / Bissantz, Caterina / Bylund, Johan / Limberg, Anja / Neidhart, Werner / Jakob-Roetne, Roland / Wang, Lisha / Baumann, Karlheinz et al. | 2020
- 8554
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Mechanistic Insight into Antiretroviral Potency of 2′-Deoxy-2′-β-fluoro-4′-azidocytidine (FNC) with a Long-Lasting Effect on HIV‑1 PreventionSun, Li / Peng, Youmei / Yu, Wenquan / Zhang, Yan / Liang, Lan / Song, Chuanjun / Hou, Jiao / Qiao, Yan / Wang, Qingduan / Chen, Jingyu et al. | 2020
- 8567
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Global PROTAC Toolbox for Degrading BCR–ABL Overcomes Drug-Resistant Mutants and Adverse EffectsYang, Yiqing / Gao, Hongying / Sun, Xiuyun / Sun, Yonghui / Qiu, Yueping / Weng, Qinjie / Rao, Yu et al. | 2020
- 8584
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Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint InhibitorsRobles, Omar / Jackson, Jeffrey J. / Marshall, Lisa / Talay, Oezcan / Chian, David / Cutler, Gene / Diokno, Raymond / Hu, Dennis X. / Jacobson, Scott / Karbarz, Emily et al. | 2020
- 8608
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Imaging Mutant Huntingtin Aggregates: Development of a Potential PET LigandLiu, Longbin / Prime, Michael E. / Lee, Matt R. / Khetarpal, Vinod / Brown, Christopher J. / Johnson, Peter D. / Miranda-Azpiazu, Patricia / Chen, Xuemei / Clark-Frew, Daniel / Coe, Samuel et al. | 2020
- 8634
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Characterization of Conformationally Constrained Benzanilide Scaffolds for Potent and Selective HDAC8 TargetingHassan, Muhammad Murtaza / Israelian, Johan / Nawar, Nabanita / Ganda, Giovanni / Manaswiyoungkul, Pimyupa / Raouf, Yasir S. / Armstrong, David / Sedighi, Abootaleb / Olaoye, Olasunkanmi O. / Erdogan, Fettah et al. | 2020
- 8649
-
Correction to “A Selective and Brain Penetrant p38αMAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction”Roy, Saktimayee M. / Minasov, George / Arancio, Ottavio / Chico, Laura W. / Van Eldik, Linda J. / Anderson, Wayne F. / Pelletier, Jeffrey C. / Watterson, D. Martin et al. | 2020
- 8650
-
Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA InhibitorsSabbah, Mohamad / Mendes, Vitor / Vistal, Robert G. / Dias, David M. G. / Záhorszká, Monika / Mikušová, Katarína / Korduláková, Jana / Coyne, Anthony G. / Blundell, Tom L. / Abell, Chris et al. | 2020