Effect of Size and N‑Terminal Residue Characteristics on Bacterial Cell Penetration and Antibacterial Activity of the Proline-Rich Peptide Bac7 (Unknown)
- New search for: Guida, Filomena
- New search for: Benincasa, Monica
- New search for: Zahariev, Sotir
- New search for: Scocchi, Marco
- New search for: Berti, Federico
- New search for: Gennaro, Renato
- New search for: Tossi, Alessandro
- New search for: Guida, Filomena
- New search for: Benincasa, Monica
- New search for: Zahariev, Sotir
- New search for: Scocchi, Marco
- New search for: Berti, Federico
- New search for: Gennaro, Renato
- New search for: Tossi, Alessandro
In:
Journal of Medicinal Chemistry
;
58
, 3
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1195-1204
;
2015
- Article (Journal) / Electronic Resource
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Title:Effect of Size and N‑Terminal Residue Characteristics on Bacterial Cell Penetration and Antibacterial Activity of the Proline-Rich Peptide Bac7
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Additional title:J. Med. Chem.
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Contributors:Guida, Filomena ( author ) / Benincasa, Monica ( author ) / Zahariev, Sotir ( author ) / Scocchi, Marco ( author ) / Berti, Federico ( author ) / Gennaro, Renato ( author ) / Tossi, Alessandro ( author )
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Published in:Journal of Medicinal Chemistry ; 58, 3 ; 1195-1204
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Publisher:
- New search for: American Chemical Society
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Publication date:2015-02-12
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Source:
Table of contents – Volume 58, Issue 3
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1019
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Computational Methods for Medicinal ChemistryBajorath, Jürgen / Jiang, Hualiang / Shoichet, Brian K. / Walters, W. Patrick et al. | 2015
- 1020
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Glucagon-like Peptide‑1 (GLP-1) Analogs: Recent Advances, New Possibilities, and Therapeutic ImplicationsManandhar, Bikash / Ahn, Jung-Mo et al. | 2015
- 1038
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Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer TreatmentZhao, Yujun / Aguilar, Angelo / Bernard, Denzil / Wang, Shaomeng et al. | 2015
- 1053
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Nintedanib: From Discovery to the ClinicRoth, Gerald J. / Binder, Rudolf / Colbatzky, Florian / Dallinger, Claudia / Schlenker-Herceg, Rozsa / Hilberg, Frank / Wollin, Stefan-Lutz / Kaiser, Rolf et al. | 2015
- 1064
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Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase Open New Prospects for the Treatment of Neurological DisordersAnnedi, Subhash C. et al. | 2015
- 1067
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Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide SynthaseMukherjee, Paramita / Li, Huiying / Sevrioukova, Irina / Chreifi, Georges / Martásek, Pavel / Roman, Linda J. / Poulos, Thomas L. / Silverman, Richard B. et al. | 2015
- 1089
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Pachymodulin, a New Functional Formyl Peptide Receptor 2 Peptidic Ligand Isolated from Frog Skin Has Janus-like Immunomodulatory CapacitiesLacombe, Claire / Piesse, Christophe / Sagan, Sandrine / Combadière, Christophe / Rosenstein, Yvonne / Auvynet, Constance et al. | 2015
- 1100
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A Series of Novel Terpyridine-Skeleton Molecule Derivants Inhibit Tumor Growth and Metastasis by Targeting TopoisomerasesKwon, Han-Byeol / Park, Chanmi / Jeon, Kyung-Hwa / Lee, Eunyoung / Park, So-Eun / Jun, Kyu-Yeon / Kadayat, Tara Man / Thapa, Pritam / Karki, Radha / Na, Younghwa et al. | 2015
- 1123
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Design, Synthesis, X‑ray Crystallographic Analysis, and Biological Evaluation of Thiazole Derivatives as Potent and Selective Inhibitors of Human Dihydroorotate DehydrogenaseZhu, Junsheng / Han, Le / Diao, Yanyan / Ren, Xiaoli / Xu, Minghao / Xu, Liuxin / Li, Shiliang / Li, Qiang / Dong, Dong / Huang, Jin et al. | 2015
- 1140
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Design, Synthesis, and Biological Evaluation of Sulfonyl Acrylonitriles as Novel Inhibitors of Cancer Metastasis and SpreadShen, Yi / Zificsak, Craig A. / Shea, Jill E. / Lao, Xuegang / Bollt, Oana / Li, Xiufen / Lisko, Joseph G. / Theroff, Jay P. / Scaife, Courtney L. / Ator, Mark A. et al. | 2015
- 1159
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Development of a Series of Aryl Pyrimidine Kynurenine Monooxygenase Inhibitors as Potential Therapeutic Agents for the Treatment of Huntington’s DiseaseToledo-Sherman, Leticia M. / Prime, Michael E. / Mrzljak, Ladislav / Beconi, Maria G. / Beresford, Alan / Brookfield, Frederick A. / Brown, Christopher J. / Cardaun, Isabell / Courtney, Stephen M. / Dijkman, Ulrike et al. | 2015
- 1184
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Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma ModelPaterni, Ilaria / Bertini, Simone / Granchi, Carlotta / Tuccinardi, Tiziano / Macchia, Marco / Martinelli, Adriano / Caligiuri, Isabella / Toffoli, Giuseppe / Rizzolio, Flavio / Carlson, Kathryn E. et al. | 2015
- 1195
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Effect of Size and N‑Terminal Residue Characteristics on Bacterial Cell Penetration and Antibacterial Activity of the Proline-Rich Peptide Bac7Guida, Filomena / Benincasa, Monica / Zahariev, Sotir / Scocchi, Marco / Berti, Federico / Gennaro, Renato / Tossi, Alessandro et al. | 2015
- 1205
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Promiscuous 2‑Aminothiazoles (PrATs): A Frequent Hitting ScaffoldDevine, Shane M. / Mulcair, Mark D. / Debono, Cael O. / Leung, Eleanor W. W. / Nissink, J. Willem M. / Lim, San Sui / Chandrashekaran, Indu R. / Vazirani, Mansha / Mohanty, Biswaranjan / Simpson, Jamie S. et al. | 2015
- 1215
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Antibacterial Drug Leads: DNA and Enzyme MultitargetingZhu, Wei / Wang, Yang / Li, Kai / Gao, Jian / Huang, Chun-Hsiang / Chen, Chun-Chi / Ko, Tzu-Ping / Zhang, Yonghui / Guo, Rey-Ting / Oldfield, Eric et al. | 2015
- 1228
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Exploration of Cyanine Compounds as Selective Inhibitors of Protein Arginine Methyltransferases: Synthesis and Biological EvaluationHu, Hao / Owens, Eric A. / Su, Hairui / Yan, Leilei / Levitz, Andrew / Zhao, Xinyang / Henary, Maged / Zheng, Yujun George et al. | 2015
- 1244
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SAR-Guided Development and Characterization of a Potent Antitumor Compound toward B‑Cell Neoplasms with No Detectable Cytotoxicity toward Healthy CellsBrunhofer-Bolzer, Gerda / Le, Trang / Dyckmanns, Nils / Knaus, Hanna A. / Pausz, Clemens / Freund, Patricia / Jäger, Ulrich / Erker, Thomas / Vanura, Katrina et al. | 2015
- 1254
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Design and Synthesis of Potent and Multifunctional Aldose Reductase Inhibitors Based on QuinoxalinonesQin, Xiangyu / Hao, Xin / Han, Hui / Zhu, Shaojuan / Yang, Yanchun / Wu, Bobin / Hussain, Saghir / Parveen, Shagufta / Jing, Chaojun / Ma, Bing et al. | 2015
- 1268
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Oleanane Triterpenes from the Flowers of Camellia japonica Inhibit Porcine Epidemic Diarrhea Virus (PEDV) ReplicationYang, Jun-Li / Ha, Thi-Kim-Quy / Dhodary, Basanta / Pyo, Euisun / Nguyen, Ngoc Hieu / Cho, Hyomoon / Kim, Eunhee / Oh, Won Keun et al. | 2015
- 1281
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Fragment-Based Drug Discovery of 2‑Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based OptimizationZhao, Lele / Wang, Yingqing / Cao, Danyan / Chen, Tiantian / Wang, Qi / Li, Yanlian / Xu, Yechun / Zhang, Naixia / Wang, Xin / Chen, Danqi et al. | 2015
- 1298
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Development of Potent Inhibitors of Pyocyanin Production in Pseudomonas aeruginosaMiller, Laura C. / O’Loughlin, Colleen T. / Zhang, Zinan / Siryaporn, Albert / Silpe, Justin E. / Bassler, Bonnie L. / Semmelhack, Martin F. et al. | 2015
- 1307
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Novel 3‑Nitrotriazole-Based Amides and Carbinols as Bifunctional Antichagasic AgentsPapadopoulou, Maria V. / Bloomer, William D. / Lepesheva, Galina I. / Rosenzweig, Howard S. / Kaiser, Marcel / Aguilera-Venegas, Benjamín / Wilkinson, Shane R. / Chatelain, Eric / Ioset, Jean-Robert et al. | 2015
- 1320
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Dual Antitumor and Antiangiogenic Activity of Organoplatinum(II) ComplexesZamora, Ana / Pérez, Sergio A. / Rodríguez, Venancio / Janiak, Christoph / Yellol, Gorakh S. / Ruiz, José et al. | 2015
- 1337
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Design, Synthesis, and Biological Evaluation of Tetrazole Analogs of Cl-Amidine as Protein Arginine Deiminase InhibitorsSubramanian, Venkataraman / Knight, Jason S. / Parelkar, Sangram / Anguish, Lynne / Coonrod, Scott A. / Kaplan, Mariana J. / Thompson, Paul R. et al. | 2015
- 1345
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Design, Synthesis, and Biological Evaluation of Combretabenzodiazepines: A Novel Class of Anti-Tubulin AgentsGalli, Ubaldina / Travelli, Cristina / Aprile, Silvio / Arrigoni, Elena / Torretta, Simone / Grosa, Giorgio / Massarotti, Alberto / Sorba, Giovanni / Canonico, Pier Luigi / Genazzani, Armando A. et al. | 2015
- 1358
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Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators: Discovery of 2‑Chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl‑1H‑imidazol-4-ylethynyl]pyridine (Basimglurant, RO4917523), a Promising Novel Medicine for Psychiatric DiseasesJaeschke, Georg / Kolczewski, Sabine / Spooren, Will / Vieira, Eric / Bitter-Stoll, Nadia / Boissin, Patrick / Borroni, Edilio / Büttelmann, Bernd / Ceccarelli, Simona / Clemann, Nicole et al. | 2015
- 1372
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Glycosylated Enfuvirtide: A Long-Lasting Glycopeptide with Potent Anti-HIV ActivityCheng, Shuihong / Chang, Xuesong / Wang, Yan / Gao, George F. / Shao, Yiming / Ma, Liying / Li, Xuebing et al. | 2015
- 1380
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Structure–Activity Relationship for the Oxadiazole Class of AntibioticsSpink, Edward / Ding, Derong / Peng, Zhihong / Boudreau, Marc A. / Leemans, Erika / Lastochkin, Elena / Song, Wei / Lichtenwalter, Katerina / O’Daniel, Peter I. / Testero, Sebastian A. et al. | 2015
- 1390
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Synthetic Peptides Reproducing Tissue Transglutaminase–Gliadin Complex Neo-epitopes as Probes for Antibody Detection in Celiac Disease Patients’ SeraDi Pisa, Margherita / Pascarella, Simona / Scrima, Mario / Sabatino, Giuseppina / Real-Fernández, Feliciana / Chelli, Mario / Renzi, Daniela / Calabrò, Antonio / D’Ursi, Anna Maria / Papini, Anna Maria et al. | 2015
- 1400
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Novel Arylalkenylpropargylamines as Neuroprotective, Potent, and Selective Monoamine Oxidase B Inhibitors for the Treatment of Parkinson’s DiseaseHuleatt, Paul B. / Khoo, Mui Ling / Chua, Yi Yuan / Tan, Tiong Wei / Liew, Rou Shen / Balogh, Balázs / Deme, Ruth / Gölöncsér, Flóra / Magyar, Kalman / Sheela, David P. et al. | 2015
- 1420
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Simple Method Provides Resolution of Albumin, Lipoprotein, Free Fraction, and Chylomicron To Enhance the Utility of Protein Binding AssaysBrockman, Adam H. / Oller, Haley R. / Moreau, Benoît / Kriksciukaite, Kristina / Bilodeau, Mark T. et al. | 2015
- 1426
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Discovery of 1H‑Pyrazol-3(2H)‑ones as Potent and Selective Inhibitors of Protein Kinase R‑like Endoplasmic Reticulum Kinase (PERK)Smith, Adrian L. / Andrews, Kristin L. / Beckmann, Holger / Bellon, Steven F. / Beltran, Pedro J. / Booker, Shon / Chen, Hao / Chung, Young-Ah / D’Angelo, Noel D. / Dao, Jennifer et al. | 2015
- 1442
-
Synthesis and Evaluation of Series of Diazine-Bridged Dinuclear Platinum(II) Complexes through in Vitro Toxicity and Molecular Modeling: Correlation between Structure and Activity of Pt(II) ComplexesSenerovic, Lidija / Zivkovic, Marija D. / Veselinovic, Aleksandar / Pavic, Aleksandar / Djuran, Milos I. / Rajkovic, Snezana / Nikodinovic-Runic, Jasmina et al. | 2015
- 1452
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Function-Oriented Development of CXCR4 Antagonists as Selective Human Immunodeficiency Virus (HIV)‑1 Entry InhibitorsWu, Chien-Huang / Wang, Chuan-Jen / Chang, Chun-Ping / Cheng, Yung-Chi / Song, Jen-Shin / Jan, Jiing-Jyh / Chou, Ming-Chen / Ke, Yi-Yu / Ma, Jing / Wong, Ying-Chieh et al. | 2015
- 1466
-
Discovery of Small Molecule Inhibitors to Krüppel-like Factor 10 (KLF10): Implications for Modulation of T Regulatory Cell DifferentiationKhedkar, Santosh A. / Sun, Xinghui / Rigby, Alan C. / Feinberg, Mark W. et al. | 2015
- 1479
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Novel 5‑Substituted Pyrrolo[2,3‑d]pyrimidines as Dual Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5‑Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase and as Potential Antitumor AgentsWang, Yiqiang / Mitchell-Ryan, Shermaine / Raghavan, Sudhir / George, Christina / Orr, Steven / Hou, Zhanjun / Matherly, Larry H. / Gangjee, Aleem et al. | 2015
- 1494
-
Carbonic Anhydrase Inhibitors with Dual-Tail Moieties To Match the Hydrophobic and Hydrophilic Halves of the Carbonic Anhydrase Active SiteTanpure, Rajendra P. / Ren, Bin / Peat, Thomas S. / Bornaghi, Laurent F. / Vullo, Daniela / Supuran, Claudiu T. / Poulsen, Sally-Ann et al. | 2015
- 1502
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2‑(2-Oxo-morpholin-3-yl)-acetamide Derivatives as Broad-Spectrum Antifungal AgentsBardiot, Dorothée / Thevissen, Karin / De Brucker, Katrijn / Peeters, Annelies / Cos, Paul / Taborda, Carlos P. / McNaughton, Michael / Maes, Louis / Chaltin, Patrick / Cammue, Bruno P. A. et al. | 2015
- 1513
-
Synthesis and Evaluation of 4‑Halogeno‑N‑[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]‑N‑[11C]methylbenzamide for Imaging of Metabotropic Glutamate 1 Receptor in MelanomaFujinaga, Masayuki / Xie, Lin / Yamasaki, Tomoteru / Yui, Joji / Shimoda, Yoko / Hatori, Akiko / Kumata, Katsushi / Zhang, Yiding / Nengaki, Nobuki / Kawamura, Kazunori et al. | 2015
- 1524
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3,4-Diaminobenzoic Acid Derivatives as Inhibitors of the Oxytocinase Subfamily of M1 Aminopeptidases with Immune-Regulating PropertiesPapakyriakou, Athanasios / Zervoudi, Efthalia / Tsoukalidou, Sofia / Mauvais, Francois-Xavier / Sfyroera, Georgia / Mastellos, Dimitrios C. / van Endert, Peter / Theodorakis, Emmanuel A. / Vourloumis, Dionisios / Stratikos, Efstratios et al. | 2015
- 1544
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Identification of the Minimum Peptide from Mouse Myostatin Prodomain for Human Myostatin InhibitionTakayama, Kentaro / Noguchi, Yuri / Aoki, Shin / Takayama, Shota / Yoshida, Momoko / Asari, Tomo / Yakushiji, Fumika / Nishimatsu, Shin-ichiro / Ohsawa, Yutaka / Itoh, Fumiko et al. | 2015
- 1550
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Proof of Concept Study for Designed Multiple Ligands Targeting the Dopamine D2, Serotonin 5‑HT2A, and Muscarinic M1 Acetylcholine ReceptorsSzabo, Monika / Lim, Herman D. / Klein Herenbrink, Carmen / Christopoulos, Arthur / Lane, J. Robert / Capuano, Ben et al. | 2015
- 1556
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Discovery of Potent Heterodimeric Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Sustained Antitumor ActivityPerez, Heidi L. / Chaudhry, Charu / Emanuel, Stuart L. / Fanslau, Caroline / Fargnoli, Joseph / Gan, Jinping / Kim, Kyoung S. / Lei, Ming / Naglich, Joseph G. / Traeger, Sarah C. et al. | 2015
- 1563
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A High-Throughput Screen Reveals New Small-Molecule Activators and Inhibitors of Pantothenate KinasesSharma, Lalit Kumar / Leonardi, Roberta / Lin, Wenwei / Boyd, Vincent A. / Goktug, Asli / Shelat, Anang A. / Chen, Taosheng / Jackowski, Suzanne / Rock, Charles O. et al. | 2015
- 1569
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Synthesis and Biological Evaluation of Second-Generation Tropanol-Based Androgen Receptor ModulatorsSundén, Henrik / Holland, Mareike C. / Poutiainen, Pekka K. / Jääskeläinen, Tiina / Pulkkinen, Juha T. / Palvimo, Jorma J. / Olsson, Roger et al. | 2015
- 1575
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Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) InhibitorNissen, Klaus B. / Andersen, Julie J. / Haugaard-Kedström, Linda M. / Bach, Anders / Strømgaard, Kristian et al. | 2015