Synthesis and Antiviral Activity of 2‘-Deoxy-4‘-thio Purine Nucleosides (Unknown)
- New search for: Van Draanen, Nanine A.
- New search for: Freeman, George A.
- New search for: Short, Steven A.
- New search for: Harvey, Robert
- New search for: Jansen, Robert
- New search for: Szczech, George
- New search for: Koszalka, George W.
- New search for: Van Draanen, Nanine A.
- New search for: Freeman, George A.
- New search for: Short, Steven A.
- New search for: Harvey, Robert
- New search for: Jansen, Robert
- New search for: Szczech, George
- New search for: Koszalka, George W.
In:
Journal of Medicinal Chemistry
;
39
, 2
;
538-542
;
1996
- Article (Journal) / Electronic Resource
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Title:Synthesis and Antiviral Activity of 2‘-Deoxy-4‘-thio Purine Nucleosides
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Additional title:J. Med. Chem.
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Contributors:Van Draanen, Nanine A. ( author ) / Freeman, George A. ( author ) / Short, Steven A. ( author ) / Harvey, Robert ( author ) / Jansen, Robert ( author ) / Szczech, George ( author ) / Koszalka, George W. ( author )
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Published in:Journal of Medicinal Chemistry ; 39, 2 ; 538-542
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Publisher:
- New search for: American Chemical Society
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Publication date:1996-01-19
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Source:
Table of contents – Volume 39, Issue 2
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 343
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Substituted 1,2-Dihydrophthalazines: Potent, Selective, and Noncompetitive Inhibitors of the AMPA ReceptorPelletier, Jeffrey C. / Hesson, David P. / Jones, Kenneth A. / Costa, Anna-Maria et al. | 1996
- 347
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(2S,3S,5R)-2-(3,5-Difluorophenyl)-3,5- dimethyl-2-morpholinol: A Novel Antidepressant Agent and Selective Inhibitor of Norepinephrine UptakeKelley, James L. / Musso, David L. / Boswell, G. Evan / Soroko, Francis E. / Cooper, Barrett R. et al. | 1996
- 350
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Two New Criteria for Choosing Sample Size in Combinatorial ChemistryZhao, Peng-Liang / Nachbar, Robert B. / Bolognese, James A. / Chapman, Kevin et al. | 1996
- 350
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Two New Criteria for Choosing Sample in Combinatorial ChemistryZhao, P.-L. / Nachbar, R. B. / Bolognese, J. A. / Chapman, K. et al. | 1996
- 353
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Potent, Cell Active, Non-Thiol Tetrapeptide Inhibitors of FarnesyltransferaseHunt, John T. / Lee, Ving G. / Leftheris, Katerina / Seizinger, Bernd / Carboni, Joan / Mabus, John / Ricca, Carol / Yan, Ning / Manne, Veeraswamy et al. | 1996
- 359
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Synthesis and Quantitative Structure−Activity Relationship of a Novel Series of Small Conductance Ca2+-Activated K+ Channel Blockers Related to DequaliniumGalanakis, Dimitrios / Davis, Carole A. / Ganellin, C. Robin / Dunn, Philip M. et al. | 1996
- 371
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2-Carbomethoxy-3-(diarylmethoxy)-1αH,5αH-tropane Analogs: Synthesis and Inhibition of Binding at the Dopamine Transporter and Comparison with Piperazines of the GBR SeriesMeltzer, Peter C. / Liang, Anna Y. / Madras, Bertha K. et al. | 1996
- 371
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2-Carbomethoxy-3-(diarylmethoxy)-1aH,5aH-tropane Analogs: Synthesis and Inhibition of Binding at the Dopamine Transporter and Comparison with Piperazines of the GBR SeriesMeltser, Peter C. et al. | 1996
- 380
-
A Comparative Molecular Field Analysis Study of N-Benzylpiperidines as Acetylcholinesterase InhibitorsTong, Weida / Collantes, Elizabeth R. / Chen, Yu / Welsh, William J. et al. | 1996
- 388
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A Study of the Active Site of Influenza Virus Sialidase: An Approach to the Rational Design of Novel Anti-influenza Drugsvon Itzstein, Mark / Dyason, Jeffrey C. / Oliver, Stuart W. / White, Hume F. / Wu, Wen-Yang / Kok, Gaik B. / Pegg, Michael S. et al. | 1996
- 392
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A Novel, Picomolar Inhibitor of Human Immunodeficiency Virus Type 1 Protease †Sham, Hing L. / Zhao, Chen / Stewart, Kent D. / Betebenner, David A. / Lin, Shuqun / Park, Chang H. / Kong, Xiang-P. / Rosenbrook, William / Herrin, Thomas / Madigan, Darold et al. | 1996
- 398
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Tetrahydrobenzothiophenone Derivatives as a Novel Class of Adenosine Receptor Antagonists †van Rhee, A. Michiel / Siddiqi, Suhaib M. / Melman, Neli / Shi, Dan / Padgett, William L. / Daly, John W. / Jacobson, Kenneth A. et al. | 1996
- 407
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Syntheses and Conformational Analyses of Glutamate Analogs: 2-(2-Carboxy-3-substituted-cyclopropyl)glycines as Useful Probes for Excitatory Amino Acid ReceptorsShimamoto, Keiko / Ohfune, Yasufumi et al. | 1996
- 407
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Syntheses and Conformational Analyses of Glutamate Analogs: 2-(2-Carboy-3-substituted-cyclopropyl)glycines as Useful Probes for Excitatory Amino Acid ReceptorsShimamoto, Keiko et al. | 1996
- 424
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Drug Delivery Systems: Water Soluble Taxol 2‘-Poly(ethylene glycol) Ester ProdrugsDesign and in Vivo EffectivenessGreenwald, Richard B. / Gilbert, Carl W. / Pendri, Annapurna / Conover, Charles D. / Xia, Jing / Martinez, Anthony et al. | 1996
- 432
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Characterizations of the Unusual Dissociation Properties of Melanotropin Peptides from the Melanocortin Receptor, hMC1RHaskell-Luevano, Carrie / Miwa, Hiroto / Dickinson, Chris / Hadley, Mac E. / Hruby, Victor J. / Yamada, Tadataka / Gantz, Ira et al. | 1996
- 436
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Studies on 6-Aminoquinolones: Synthesis and Antibacterial Evaluation of 6-Amino-8-methylquinolonesCecchetti, Violetta / Fravolini, Arnaldo / Lorenzini, Maria Cristina / Tabarrini, Oriana / Terni, Patrizia / Xin, Tao et al. | 1996
- 446
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The Chemistry of Pseudomonic Acid. † 15. Synthesis and Antibacterial Activity of a Series of 5-Alkyl, 5-Alkenyl, and 5-Heterosubstituted OxazolesBrown, Pamela / Davies, David T. / O'Hanlo, Peter J. / Wilson, Jennifer M. et al. | 1996
- 458
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Indium(III) and Gallium(III) Complexes of Bis(aminoethanethiol) Ligands with Different Denticities: Stabilities, Molecular Modeling, and in Vivo BehaviorSun, Yizhen / Anderson, Carolyn J. / Pajeau, Tammy S. / Reichert, David E. / Hancock, Robert D. / Motekaitis, Ramunas J. / Martell, Arthur E. / Welch, Michael J. et al. | 1996
- 471
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Structure−Activity Analysis of Anandamide Analogs: Relationship to a Cannabinoid Pharmacophore †Thomas, Brian F. / Adams, Irma B. / Mascarella, S. Wayne / Martin, Billy R. / Razdan, Raj K. et al. | 1996
- 480
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Investigation of (Oxodioxolenyl)methyl Carbamates as Nonchiral Bioreversible Prodrug Moieties for Chiral AminesAlexander, Jose / Bindra, Dilbir S. / Glass, Joan D. / Holahan, Marie A. / Renyer, Mara L. / Rork, Gerald S. / Sitko, Gary R. / Stranieri, Maria T. / Stupienski, Raymond F. / Veerapanane, Hemalata et al. | 1996
- 487
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Design, Synthesis, and Structure−Activity Relationship Studies of Novel 1-[(1-Acyl-4-piperidyl)methyl]-1H-2-methylimidazo[4,5-c]pyridine Derivatives as Potent, Orally Active Platelet−Activating Factor AntagonistsCarceller, Elena / Merlos, Manuel / Giral, Marta / Balsa, Dolors / García-Rafanell, Julián / Forn, Javier et al. | 1996
- 487
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Design Synthesis, Structure-Activity Relationship Studies of Novel 1-[(1-Acyl-4-piperidyl)methyl]-1H-2-methylimidazo[4,5-c]pyridyne Derivatives as Potent, Orally Active Platelet-Activating Factor AntagonistsCarceller, E. / Merlos, M. / Giral, M. / Balsa, D. / Garcia-Rafanell, J. / Forn, J. et al. | 1996
- 494
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Dual Metalloprotease Inhibitors. 6. Incorporation of Bicyclic and Substituted Monocyclic Azepinones as Dipeptide Surrogates in Angiotensin-Converting Enzyme/Neutral Endopeptidase InhibitorsRobl, Jeffrey A. / Cimarusti, Maria P. / Simpkins, Ligaya M. / Brown, Baerbel / Ryono, Denis E. / Bird, J. Eileen / Asaad, Magdi M. / Schaeffer, Thomas R. / Trippodo, Nick C. et al. | 1996
- 494
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Dual Metalloprotease Inhibitors. 6. Incorporation of Bicyclic and Substituted Monacyclic Azepinones as Dipeptide Surrogates in Angiotensin-Converting Enzyme/Neutral Endopeptidase InhibitorsRobl, J. A. / Cimarusti, M. P. / Simpkins, L. M. / Brown, B. / Ryono, D. E. / Bird, J. E. / Asaad, M. M. / Schaeffer, T. R. / Trippodo, N. C. et al. | 1996
- 503
-
Metal-Chelating Inhibitors of a Zinc Finger Protein HIV-EP1. Remarkable Potentiation of Inhibitory Activity by Introduction of SH GroupsFujita, Mikako / Otsuka, Masami / Sugiura, Yukio et al. | 1996
- 508
-
Correlation of Anti-HIV Potency with Lipophilicity in a Series of Cosalane Analogs Having Normal Alkenyl and Phosphodiester Chains as Cholestane ReplacementsKeyes, Robert F. / Golebiewski, W. Marek / Cushman, Mark et al. | 1996
- 515
-
Neuroactive Polyamine Wasp Toxins: Nuclear Magnetic Resonance Spectroscopic Analysis of the Protolytic Properties of Philanthotoxin-343Jaroszewski, Jerzy W. / Matzen, Lisa / Frølund, Bente / Krogsgaard-Larsen, Povl et al. | 1996
- 522
-
2-Sulfonyl-4-chloroanilino Moiety: A Potent Pharmacophore for the Anti-Human Immunodeficiency Virus Type 1 Activity of Pyrrolyl Aryl SulfonesArtico, Marino / Silvestri, Romano / Massa, Silvio / Loi, Anna G. / Corrias, Simona / Piras, Giovanna / La Colla, Paolo et al. | 1996
- 531
-
Cross-Linking and Sequence Specific Alkylation of DNA by Aziridinylquinones. 1. Quinone MethidesMayalarp, Stephen P. / Hargreaves, Rob H. J. / Butler, John / O'Hare, C. Caroline / Hartley, John A. et al. | 1996
- 538
-
Synthesis and Antiviral Activity of 2‘-Deoxy-4‘-thio Purine NucleosidesVan Draanen, Nanine A. / Freeman, George A. / Short, Steven A. / Harvey, Robert / Jansen, Robert / Szczech, George / Koszalka, George W. et al. | 1996
- 543
-
N-Substituted Analogs of 2b-Carbomethoxy-3b-(4-iodophenyl)tropane (b-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat ForebrainNeumeyer, John L. et al. | 1996
- 543
-
N-Substituted Analogs of 2β-Carbomethoxy-3β-(4‘-iodophenyl)tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat ForebrainNeumeyer, John L. / Tamagnan, Gilles / Wang, Shaoyin / Gao, Yigong / Milius, Richard A. / Kula, Nora S. / Baldessarini, Ross J. et al. | 1996
- 549
-
8,9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: A Potent Full Dopamine D1 Agonist Containing a Rigid β-Phenyldopamine PharmacophoreGhosh, Debasis / Snyder, Scott E. / Watts, Val J. / Mailman, Richard B. / Nichols, David E. et al. | 1996
- 549
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8,9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph(1,2,3 de)isoquinoline: A Potent Full Dopamine D1 Agonist Containing a Rigid b-Phenyldopamine PharmacophoreGhosh, Debasis et al. | 1996
- 556
-
Approaches to Short-Acting Neuromuscular Blocking Agents: Nonsymmetrical Bis-tetrahydroisoquinolinium Mono- and DiestersDhar, Nirmal C. / Maehr, Robert B. / Masterson, Luke A. / Midgley, John M. / Stenlake, John B. / Wastila, William B. et al. | 1996
- 562
-
Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”Aquino, Christopher J. / Armour, Duncan R. / Berman, Judd M. / Birkemo, Larry S. / Carr, Robin A. E. / Croom, Dallas K. / Dezube, Milana / Dougherty,, Robert W. / Ervin, Gregory N. / Grizzle, Mary K. et al. | 1996
- 570
-
Synthesis and Structure−Activity Relationships of N-Propyl-N-(4-pyridinyl)-1H-indol-1-amine (Besipirdine) and Related Analogs as Potential Therapeutic Agents for Alzheimer's DiseaseKlein, Joseph T. / Davis, Larry / Olsen, Gordon E. / Wong, George S. / Huger, Francis P. / Smith, Craig P. / Petko, Wayne W. / Cornfeldt, Michael / Wilker, Jeffrey C. / Blitzer, R. D. et al. | 1996
- 570
-
Synthesis and Structure-Activity Relationships of N-Propyl-N-(4-pyridinyl)-1H-indol. 1-amino (Besipirdine) and Related Analogs as Potential Therapeutic Agents for Alzheimer's DiseaseKlein, J. T. / Davis, L. / Olsen, G. E. / Wong, G. S. / Huger, F. P. / Smith, C. P. / Petko, W. W. / Cornfeldt, M. / Wilker, J. C. / Blitzer, R. D. et al. | 1996
- 582
-
Substituted (Pyrroloamino)pyridines: Potential Agents for the Treatment of Alzheimer's DiseaseDavis, Larry / Klein, Joseph T. / Kapples, Kevin J. / Huger, Francis P. / Smith, Craig P. / Petko, Wayne W. / Cornfeldt, Michael / Effland, Richard C. et al. | 1996
- 588
-
Ionophore Properties of Monensin Derivatives Studied on Human Erythroctes by 23Na NMR and K+ and H+ Potentiometry: Relationship with Antimicrobial and Antimalarial ActivitiesRochdi, Mohamed et al. | 1996
- 588
-
Ionophore Properties of Monensin Derivatives Studied on Human Erythrocytes by 23Na NMR and K+ and H+ Potentiometry: Relationship with Antimicrobial and Antimalarial ActivitiesRochdi, Mohamed / Delort, Anne-Marie / Guyot, Jacques / Sancelme, Martine / Gibot, Sylvie / Gourcy, Jean-Gabriel / Dauphin, Gérard / Gumila, Catherine / Vial, Henri / Jeminet, Georges et al. | 1996
- 596
-
2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent[d]imidazoles as a Novel Class of Gastric H+/K+-ATPase InhibitorsYamada, Masaki / Yura, Takeshi / Morimoto, Masamichi / Harada, Tsunehiro / Yamada, Koichiro / Honma, Yasushi / Kinoshita, Mine / Sugiura, Masaki et al. | 1996
- 605
-
Antitumor Activity of the R- and S-Enantiomers of RS-2-[[Hydroxy[[2-[(octadecyloxy)methyl]tetrahydrofuran-2-yl]methoxy]phosphinyl]oxy]-N,N,N-trimethylethylaminium Hydroxide Inner SaltHoulihan, William J. / Prasad, Kapa / Underwood, Russell / Repič, Oljan / Munder, Paul G. et al. | 1996
- 609
-
Aminoacetyl Moiety as a Potential Surrogate for Diacylhydrazine Group of SC-51089, a Potent PGE2 Antagonist, and Its AnalogsHallinan, E. Ann / Hagen, Timothy J. / Tsymbalov, Sofya / Husa, Robert K. / Lee, Albert C. / Stapelfeld, Awilda / Savage, Michael A. et al. | 1996
- 614
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Analogues of 10-Deazaaminopterin and 5-Alkyl-5,10-dideazaaminopterin with the 4-Substituted 1-Naphthoyl Group in the Place of 4-Substituted BenzoylPiper, James R. / Ramamurthy, Balakrishnan / Johnson, Cheryl A. / Otter, Glenys M. / Sirotnak, Francis M. et al. | 1996
- 619
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Design, Synthesis, and Biological Activity of a Potent Inhibitor of the Neuropeptidase N-Acetylated α-Linked Acidic DipeptidaseJackson, Paul F. / Cole, Derek C. / Slusher, Barbara S. / Stetz, Susan L. / Ross, Laurie E. / Donzanti, Bruce A. / Trainor, Diane Amy et al. | 1996
- 619
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Design, Synthesis, and Biological Activity of a Potent Inhibitor of the Neuropeptidase N-Acetylated a-Linked Acidic DipeptidaseJackson, Paul F. et al. | 1996
- 623
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Books of Interest| 1996
- 623
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KetenesMewshaw, Richard E. et al. | 1996
- 623
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Ketenes Thomas T. Tidwell. John Wiley & Sons, Inc., New York. 1995. xv + 665 pp. 16.5 × 24.5 cm. ISBN 0-471-57580-1. $69.95.Mewshaw, Richard E. et al. | 1996
- 624
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Synthesis and Antiviral Activity of Benzyl-Substituted Imidazo(1,5-a)-1,3,5-triazine (5,8-Diaza-7,9-dideazapurine) DerivativesGolankiewicz, Bozenna et al. | 1996