Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons (English)
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In:
ACS Chemical Neuroscience
;
14
, 24
;
4363-4382
;
2023
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons
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Additional title:ACS Chem. Neurosci.
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Contributors:Hippman, Ryan S. ( author ) / Snead, Amanda M. ( author ) / Petros, Zoe A. ( author ) / Korkmaz-Vaisys, Melissa A. ( author ) / Patel, Sruchi ( author ) / Sotelo, Daniel ( author ) / Dobria, Andrew ( author ) / Salkovski, Maryna ( author ) / Nguyen, Thu T. A. ( author ) / Linares, Ricardo ( author )
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Published in:ACS Chemical Neuroscience ; 14, 24 ; 4363-4382
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Publisher:
- New search for: American Chemical Society
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Publication date:2023-12-20
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Licence:
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Source:
Table of contents – Volume 14, Issue 24
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 4264
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Techniques for Measurement of Serotonin: Implications in Neuropsychiatric Disorders and Advances in Absolute Value Recording MethodsRojas Cabrera, Juan M. / Oesterle, Tyler S. / Rusheen, Aaron E. / Goyal, Abhinav / Scheitler, Kristen M. / Mandybur, Ian / Blaha, Charles D. / Bennet, Kevin E. / Heien, Michael L. / Jang, Dong Pyo et al. | 2023
- 4274
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Initiation of Brain Extract Fibrillation and Effective Cellular Internalization of Tryptophan Fibrils Unveils Its Neurotoxicity RiskPrajapati, Kailash Prasad / Ansari, Masihuzzaman / Mittal, Shikha / Anand, Bibin Gnanadhason / Kar, Karunakar et al. | 2023
- 4282
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Disease-Associated Mutations in Tau Encode for Changes in Aggregate Structure ConformationSun, Kerry T. / Patel, Tark / Kang, Sang-Gyun / Yarahmady, Allan / Srinivasan, Mahalashmi / Julien, Olivier / Heras, Jónathan / Mok, Sue-Ann et al. | 2023
- 4298
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Neuroprotective Profile of Triazole Grandisin Analogue against Amyloid-Beta Oligomer-Induced Cognitive ImpairmentAndrade, Victor H. B. de / M. Rodrigues, Erick Y. / Dias, Nayara A. F. / Ferreira, Gabriela F. C. / Carvalho, Diego B. de / das Neves, Amarith R. / Coronel, Paola M. V. / Yonekawa, Murilo K. A. / Parisotto, Eduardo B. / Santos, Edson A. dos et al. | 2023
- 4311
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Basic Residues at Position 11 of α‑Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic MechanismHaufe, Yves / Kuruva, Veeresh / Samanani, Ziyana / Lokaj, Gonxhe / Kamnesky, Guy / Shadamarshan, PranavKumar / Shahoei, Rezvan / Katz, Dana / Sampson, Jared M. / Pusch, Michael et al. | 2023
- 4323
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Characterization of (R)- and (S)‑[18F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N‑Methyl‑d‑Aspartate ReceptorsAhmed, Hazem / Wallimann, Rahel / Gisler, Livio / Elghazawy, Nehal H. / Gruber, Stefan / Keller, Claudia / Liang, Steven H. / Sippl, Wolfgang / Haider, Ahmed / Ametamey, Simon M. et al. | 2023
- 4335
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Ganglioside Micelles Affect Amyloid β Aggregation by CoassemblyHu, Jing / Linse, Sara / Sparr, Emma et al. | 2023
- 4344
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Repurposing of the PET Probe Prototype PiB for Label and Radiation-Free CEST MRI Molecular Imaging of AmyloidZhuang, Caiyu / Chen, Beibei / Wu, Shuohua / Xu, Liang / Zhang, Xiaolei / Zheng, Xinhui / Chen, Yue / Geng, Yiqun / Guan, Jitian / Lin, Yan et al. | 2023
- 4352
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Genome-Wide 5‑Formylcytosine Redistribution in KCl-Stimulated Mouse Primary Cortical Neurons is Associated with Neuronal ActivityWu, Du / Huang, Kaixin / Shi, Jichun / Liu, Sha / Wang, Wenjing / Jiang, Jiazhi / Ren, Haobin / Chen, Tongyu / Ye, Shengda / Chen, Jincao et al. | 2023
- 4363
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Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in NeuronsHippman, Ryan S. / Snead, Amanda M. / Petros, Zoe A. / Korkmaz-Vaisys, Melissa A. / Patel, Sruchi / Sotelo, Daniel / Dobria, Andrew / Salkovski, Maryna / Nguyen, Thu T. A. / Linares, Ricardo et al. | 2023
- 4383
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Glutathione Depletion and Concomitant Elevation of Susceptibility in Patients with Parkinson’s Disease: State-of-the-Art MR Spectroscopy and Neuropsychological StudyShukla, Deepika / Goel, Anshika / Mandal, Pravat K. / Joon, Shallu / Punjabi, Khushboo / Arora, Yashika / Kumar, Rajnish / Mehta, Veer Singh / Singh, Padam / Maroon, Joseph C. et al. | 2023
- 4395
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Computationally Designed Molecules Modulate ALS-Related Amyloidogenic TDP-43307–319 AggregationLiu, Xikun / Duan, Shuya / Jin, Yingying / Walker, Ethan / Tsao, Michelle / Jang, Joshua H. / Chen, Ziying / Singh, Ambuj K. / Cantrell, Kristi Lazar / Ingolfsson, Helgi I. et al. | 2023
- 4409
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Synthesis and Preclinical Evaluation of 22‑[18F]Fluorodocosahexaenoic Acid as a Positron Emission Tomography Probe for Monitoring Brain Docosahexaenoic Acid Uptake KineticsDuro, Marlon Vincent V. / Van Valkenburgh, Juno / Ingles, Diana E. / Tran, Jenny / Cai, Zhiheng / Ebright, Brandon / Wang, Shaowei / Kerman, Bilal E. / Galvan, Jasmin / Hwang, Sung Hee et al. | 2023