Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as antimitotic agents with apoptosis inducing ability (English)
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- New search for: Malik, M. Shaheer
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In:
Bioorganic and Medicinal Chemistry Letters
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26
, 18
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4527-4535
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2016
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as antimitotic agents with apoptosis inducing ability
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Contributors:Ashraf, Md. ( author ) / Shaik, Thokhir B. ( author ) / Malik, M. Shaheer ( author ) / Syed, Riyaz ( author ) / Mallipeddi, Prema L. ( author ) / Vardhan, M.V.P.S. Vishnu ( author ) / Kamal, Ahmed ( author )
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Published in:Bioorganic and Medicinal Chemistry Letters ; 26, 18 ; 4527-4535
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Publisher:
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Publication date:2016-06-16
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Size:9 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 26, Issue 18
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 4387
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Recent progress on nuclear receptor RORγ modulatorsCyr, Patrick / Bronner, Sarah M. / Crawford, James J. et al. | 2016
- 4394
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Emerging therapeutics for the treatment of diabetic nephropathyBrenneman, Jehrod / Hill, Jon / Pullen, Steve et al. | 2016
- 4403
-
Development of indole sulfonamides as cannabinoid receptor negative allosteric modulatorsGreig, Iain R. / Baillie, Gemma L. / Abdelrahman, Mostafa / Trembleau, Laurent / Ross, Ruth A. et al. | 2016
- 4408
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Synthesis and antitumor activity evaluation of 4,6-disubstituted quinazoline derivatives as novel PI3K inhibitorsHei, Yuan-Yuan / Xin, Minhang / Zhang, Hao / Xie, Xiao-Xiao / Mao, Shuai / Zhang, San-Qi et al. | 2016
- 4414
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Synthesis and in vitro antiproliferative evaluation of novel nonsymmetrical disulfides bearing 1,3,4-oxadiazole moietyZhao, Ji-Jun / Wang, Xue-Feng / Li, Bao-Lin / Zhang, Rui-Lian / Li, Bo / Liu, Yu-Ming / Li, Cai-Wen / Liu, Jin-Biao / Chen, Bao-Quan et al. | 2016
- 4417
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Flavonoids and biphenylneolignans with anti-inflammatory activity from the stems of Millettia griffithiiTang, Huan / Pei, He-Ying / Wang, Tai-Jin / Chen, Kai / Wu, Bo / Yang, Qiu-Nan / Zhang, Qiang / Yang, Jian-Hong / Wang, Xiao-Yan / Tang, Ming-Hai et al. | 2016
- 4423
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Piperazic acid derivatives inhibit Gli1 in Hedgehog signaling pathwayKhatra, Harleen / Kundu, Jayanta / Khan, Pragya Paramita / Duttagupta, Indranil / Pattanayak, Sankha / Sinha, Surajit et al. | 2016
- 4427
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Synthesis of novel hydrazone and azole functionalized pyrazolo[3,4-b]pyridine derivatives as promising anticancer agentsNagender, P. / Naresh Kumar, R. / Malla Reddy, G. / Krishna Swaroop, D. / Poornachandra, Y. / Ganesh Kumar, C. / Narsaiah, B. et al. | 2016
- 4433
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A fluorescence polarization based assay for the identification and characterization of polymerase inhibitorsNasiri, Hamid R. / Kiss, László / Krämer, Joachim et al. | 2016
- 4436
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Design, synthesis, and protein methyltransferase activity of a unique set of constrained amine containing compoundsZhou, Hao / Che, Xin / Bao, Guochen / Wang, Na / Peng, Li / Barnash, Kimberly D. / Frye, Stephen V. / James, Lindsey I. / Bai, Xu et al. | 2016
- 4441
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Synthesis and in vitro evaluation of water-soluble 1,4-diphenethylpiperazine analogs as novel inhibitors of the vesicular monoamine transporter-2Nickell, Justin R. / Culver, John P. / Janganati, Venumadhav / Zheng, Guangrong / Dwoskin, Linda P. / Crooks, Peter A. et al. | 2016
- 4446
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Synthesis and activity of benzimidazole-1,3-dioxide inhibitors of separaseDo, Ha T. / Zhang, Nenggang / Pati, Debananda / Gilbertson, Scott R. et al. | 2016
- 4451
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Synthesis and anticancer activity of a hydroxytolan seriesLin, Boren / McGuire, Karen / Liu, Bo / Jamison, James / Tsai, Chun-che et al. | 2016
- 4455
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Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME propertiesRené, Olivier / Fauber, Benjamin P. / Barnard, Adrian / Chapman, Kerry / Deng, Yuzhong / Eidenschenk, Céline / Everett, Christine / Gobbi, Alberto / Johnson, Adam R. / La, Hank et al. | 2016
- 4462
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The contribution of adenines in the catalytic core of 10-23 DNAzyme improved by the 6-amino group modificationsZhu, Junfei / Li, Zhiwen / Wang, Qi / Liu, Yang / He, Junlin et al. | 2016
- 4466
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Design, synthesis and evaluation of the multidrug resistance-reversing activity of pyridine acid esters of podophyllotoxin in human leukemia cellsZhang, Lei / Chen, Fan / Zhang, Zeguo / Chen, Yongzheng / Lin, Ya / Wang, Jing et al. | 2016
- 4472
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Design and synthesis of benzylpiperidine inhibitors targeting the menin–MLL1 interfaceRen, Jing / Xu, Wei / Tang, Le / Su, Minbo / Chen, Danqi / Chen, Yue-Lei / Zang, Yi / Li, Jia / Shen, Jingkang / Zhou, Yubo et al. | 2016
- 4477
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Highly sensitive and selective detection of Al(III) ions in aqueous buffered solution with fluorescent peptide-based sensorIn, Byunggyu / Hwang, Gi Won / Lee, Keun-Hyeung et al. | 2016
- 4483
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Design, synthesis and biological evaluation of c-Met kinase inhibitors bearing 2-oxo-1,2-dihydroquinoline scaffoldCui, Hong / Peng, Xia / Liu, Jian / Ma, Chunhua / Ji, Yinchun / Zhang, Wei / Geng, Meiyu / Li, Yingxia et al. | 2016
- 4487
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Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypesGeanes, Alexander R. / Cho, Hykeyung P. / Nance, Kellie D. / McGowan, Kevin M. / Conn, P. Jeffrey / Jones, Carrie K. / Meiler, Jens / Lindsley, Craig W. et al. | 2016
- 4492
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Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitorsLabadie, Sharada S. / Dragovich, Peter S. / Cummings, Richard T. / Deshmukh, Gauri / Gustafson, Amy / Han, Ning / Harmange, Jean-Christophe / Kiefer, James R. / Li, Yue / Liang, Jun et al. | 2016
- 4497
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Nature-inspired design of tetraindoles: Optimization of the core structure and evaluation of structure–activity relationshipAbdu-Allah, Hajjaj H.M. / Huang, Shih-Ting / Chang, Tzu Ting / Chen, Chia-Ling / Wu, Han-Chung / Li, Wen-Shan et al. | 2016
- 4504
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Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moietyDai, Hong / Ge, Shushan / Li, Gang / Chen, Jia / Shi, Yujun / Ye, Linyu / Ling, Yong et al. | 2016
- 4508
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Discovery of ravidasvir (PPI-668) as a potent pan-genotypic HCV NS5A inhibitorZhong, Min / Peng, Eric / Huang, Ningwu / Huang, Qi / Huq, Anja / Lau, Meiyen / Colonno, Richard / Li, Leping et al. | 2016
- 4513
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Systematic chemical modifications of single stranded siRNAs significantly improved CTNNB1 mRNA silencingChang, Wonsuk / Pei, Yi / Guidry, Erin N. / Zewge, Daniel / Parish, Craig A. / Sherer, Edward C. / DiMuzio, Jillian / Zhang, Hangchun / South, Victoria J. / Strapps, Walter R. et al. | 2016
- 4518
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New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atomsSpurr, Sophie S. / Bayle, Elliott D. / Yu, Wenyu / Li, Fengling / Tempel, Wolfram / Vedadi, Masoud / Schapira, Matthieu / Fish, Paul V. et al. | 2016
- 4523
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Synthesis and activity of novel homodimers of Morita–Baylis–Hillman adducts against Leishmania donovani: A twin drug approachda Silva, Wagner A.V. / Rodrigues, Daniele C. / de Oliveira, Ramon G. / Mendes, Rhuan K.S. / Olegário, Tayná R. / Rocha, Juliana C. / Keesen, Tatjana S.L. / Lima-Junior, Claudio G. / Vasconcellos, Mário L.A.A. et al. | 2016
- 4527
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Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as antimitotic agents with apoptosis inducing abilityAshraf, Md. / Shaik, Thokhir B. / Malik, M. Shaheer / Syed, Riyaz / Mallipeddi, Prema L. / Vardhan, M.V.P.S. Vishnu / Kamal, Ahmed et al. | 2016
- 4536
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Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerasePierra Rouvière, Claire / Amador, Agnès / Badaroux, Eric / Convard, Thierry / Da Costa, Daniel / Dukhan, David / Griffe, Ludovic / Griffon, Jean-François / LaColla, Massimiliano / Leroy, Frédéric et al. | 2016
- 4542
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A selective inhibitor of the UFM1-activating enzyme, UBA5da Silva, Sara R. / Paiva, Stacey-Lynn / Bancerz, Matthew / Geletu, Mulu / Lewis, Andrew M. / Chen, Jijun / Cai, Yafei / Lukkarila, Julie L. / Li, Honglin / Gunning, Patrick T. et al. | 2015
- 4548
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Design, synthesis and antimicrobial activity of 6-N-substituted chitosan derivativesHu, Linfeng / Meng, Xiangtao / Xing, Ronge / Liu, Song / Chen, Xiaolin / Qin, Yukun / Yu, Huahua / Li, Pengcheng et al. | 2015
- 4552
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Synthesis and biological evaluation of novel (E)-N′-(2,3-dihydro-1H-inden-1-ylidene) benzohydrazides as potent LSD1 inhibitorsZhou, Yang / Li, Yan / Wang, Wen-Jing / Xiang, Pu / Luo, Xin-Mei / Yang, Li / Yang, Sheng-Yong / Zhao, Ying-Lan et al. | 2015
- 4558
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Corrigendum to “Synthesis and biological evaluation of novel benzamide derivatives as potent smoothened antagonists” [Bioorg. Med. Chem. Lett. 24/5 (2014) 1426–1431]Wu, Tian-Ming / Wang, Dao-Cai / Xiang, Pu / Zhang, Jian-Nan / Sang, Ya-Xiong / Lin, Hong-Jun / Chen, Jie / Xie, Gang / Song, Hang / Zhao, Ying-Lan et al. | 2016
- IFC
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Editorial board| 2016