Carbonic anhydrase inhibitors (English)
- New search for: Supuran, Claudiu T.
- New search for: Supuran, Claudiu T.
In:
Bioorganic and Medicinal Chemistry Letters
;
20
, 12
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3467-3474
;
2010
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Carbonic anhydrase inhibitors
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Contributors:Supuran, Claudiu T. ( author )
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Published in:Bioorganic and Medicinal Chemistry Letters ; 20, 12 ; 3467-3474
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Publisher:
- New search for: Elsevier Ltd
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Publication date:2010-05-05
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Size:8 pages
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ISSN:
-
DOI:
-
Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 20, Issue 12
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 3445
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Graphical contents list| 2010
- 3467
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Carbonic anhydrase inhibitorsSupuran, Claudiu T. et al. | 2010
- 3475
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Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramidesJervis, Peter J. / Veerapen, Natacha / Bricard, Gabriel / Cox, Liam R. / Porcelli, Steven A. / Besra, Gurdyal S. et al. | 2010
- 3475
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Synthesis and biological activity of a-glucosyl C24:0 and C20:2 ceramidesJervis, P. J. / Veerapen, N. / Bricard, G. / Cox, L. R. / Porcelli, S. A. / Besra, G. S. et al. | 2010
- 3479
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Self-propagating artificial transcription factors to enhance upregulation of target genesMori, Tomoaki / Sasaki, Jun / Saito, Yoshiaki / Aoyama, Yasuhiro / Sera, Takashi et al. | 2010
- 3482
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Synthesis and in vitro evaluation of 18F labeled tyrosine derivatives as potential positron emission tomography (PET) imaging agentsWang, Limin / Qu, Wenchao / Lieberman, Brian / Ploessl, Karl / Kung, Hank F. et al. | 2010
- 3486
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Towards Gram-positive antivirulence drugs: New inhibitors of Streptococcus agalactiae Stk1Oxoby, Mayalen / Moreau, François / Durant, Lionel / Denis, Alexis / Genevard, Jean-Marie / Vongsouthi, Vanida / Escaich, Sonia / Gerusz, Vincent et al. | 2010
- 3491
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Structure–activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitorsCuny, Gregory D. / Robin, Maxime / Ulyanova, Natalia P. / Patnaik, Debasis / Pique, Valerie / Casano, Gilles / Liu, Ji-Feng / Lin, Xiangjie / Xian, Jun / Glicksman, Marcie A. et al. | 2010
- 3495
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Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): Their effects on three selected glycolytic enzymes of Trypanosoma bruceiNgantchou, Igor / Nyasse, Barthélemy / Denier, Colette / Blonski, Casimir / Hannaert, Véronique / Schneider, Bernd et al. | 2010
- 3499
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Synthesis, in vitro and in vivo evaluation of [11C]MMTP: A potential PET ligand for mGluR1 receptorsPrabhakaran, Jaya / Majo, Vattoly J. / Milak, Matthew S. / Kassir, Suham A. / Palner, Mikael / Savenkova, Lyudmila / Mali, Pratap / Arango, Victoria / Mann, J. John / Parsey, Ramin V. et al. | 2010
- 3502
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Discovery of a novel sulfonamide-pyrazolopiperidine series as potent and efficacious γ-secretase inhibitors (Part II)Ye, Xiaocong M. / Konradi, Andrei W. / Smith, Jenifer / Aubele, Danielle L. / Garofalo, Albert W. / Marugg, Jennifer / Neitzel, Marty L. / Semko, Chris M. / Sham, Hing L. / Sun, Minghua et al. | 2010
- 3502
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Discovery of a novel sulfonamide-pyrazolopiperidine series as potent and efficacious g-secretase inhibitors (Part II)Ye, X. M. / Konradi, A. W. / Smith, J. / Aubele, D. L. / Garofalo, A. W. / Marugg, J. / Neitzel, M. L. / Semko, C. M. / Sham, H. L. / Sun, M. et al. | 2010
- 3507
-
Discovery of novel 1-phenyl-cycloalkane carbamides as potent and selective influenza fusion inhibitorsTang, Guozhi / Qiu, Zongxing / Lin, Xianfeng / Li, Wentao / Zhu, Lei / Li, Shaohua / Li, Haodong / Wang, Lisha / Chen, Li / Wu, Jim Z. et al. | 2010
- 3511
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Discovery of a series of indan carboxylic acid glycogen phosphorylase inhibitorsBennett, Stuart N.L. / Campbell, Andrew D. / Hancock, Andrew / Johnstone, Craig / Kenny, Peter W. / Pickup, Adrian / Plowright, Alleyn T. / Selmi, Nidhal / Simpson, Iain / Stocker, Andy et al. | 2010
- 3515
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Synthesis of the Cyanine 7 labeled neutrophil-specific agents for noninvasive near infrared fluorescence imagingXiao, Li / Zhang, Yi / Liu, Zhongqiu / Yang, Min / Pu, Lin / Pan, Dongfeng et al. | 2010
- 3518
-
Potent antimicrobial activity of 3-(4,5-diaryl-1H-imidazol-2-yl)-1H-indole derivatives against methicillin-resistant Staphylococcus aureusAl-Qawasmeh, Raed A. / Huesca, Mario / Nedunuri, Venkata / Peralta, Robert / Wright, Jim / Lee, Yoon / Young, Aiping et al. | 2010
- 3521
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Synthesis and biological evaluation of bicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetesCho, Tang Peng / Gang, Lin Zhi / Long, Yang Fang / Yang, Wang / Qian, Wang / Lei, Zhang / Jing, Luo Jing / Ying, Feng / Ke, Yan Pang / Ying, Leng et al. | 2010
- 3526
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5-Ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-α and mTOR for the treatment of breast cancerZhang, Nan / Ayral-Kaloustian, Semiramis / Anderson, James T. / Nguyen, Thai / Das, Sasmita / Venkatesan, Aranapakam M. / Brooijmans, Natasja / Lucas, Judy / Yu, Ker / Hollander, Irwin et al. | 2010
- 3526
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5-Ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-a and mTOR for the treatment of breast cancerZhang, N. / Ayral-Kaloustian, S. / Anderson, J. T. / Nguyen, T. / Das, S. / Venkatesan, A. M. / Brooijmans, N. / Lucas, J. / Yu, K. / Hollander, I. et al. | 2010
- 3530
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Crystal structure of an intermolecular 2:1 complex between adenine and thymine. Evidence for both Hoogsteen and ‘quasi-Watson–Crick’ interactionsChandrasekhar, Sosale / Naik, Tangali R. Ravikumar / Nayak, Susanta K. / Row, Tayur N. Guru et al. | 2010
- 3534
-
Anti HIV-1 agents 5: Synthesis and anti-HIV-1 activity of some N-arylsulfonyl-3-acetylindoles in vitroRan, Jun-Qiang / Huang, Ning / Xu, Hui / Yang, Liu-Meng / Lv, Min / Zheng, Yong-Tang et al. | 2010
- 3537
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Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanideBallard, T. Eric / Wang, Xia / Olekhnovich, Igor / Koerner, Taylor / Seymour, Craig / Hoffman, Paul S. / Macdonald, Timothy L. et al. | 2010
- 3540
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2′ Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SARBudzik, Brian / Garzya, Vincenzo / Shi, Dongchuan / Foley, James J. / Rivero, Ralph A. / Langmead, Christopher J. / Watson, Jeannette / Wu, Zining / Forbes, Ian T. / Jin, Jian et al. | 2010
- 3540
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2prime Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SARBudzik, B. / Garzya, V. / Shi, D. / Foley, J. J. / Rivero, R. A. / Langmead, C. J. / Watson, J. / Wu, Z. / Forbes, I. T. / Jin, J. et al. | 2010
- 3545
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2′ Biaryl amides as novel and subtype selective M1 agonists. Part II: Further optimization and profilingBudzik, Brian / Garzya, Vincenzo / Shi, Dongchuan / Walker, Graham / Lauchart, Yann / Lucas, Adam J. / Rivero, Ralph A. / Langmead, Christopher J. / Watson, Jeannette / Wu, Zining et al. | 2010
- 3545
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2prime Biaryl amides as novel and subtype selective M1 agonists. Part II: Further optimization and profilingBudzik, B. / Garzya, V. / Shi, D. / Walker, G. / Lauchart, Y. / Lucas, A. J. / Rivero, R. A. / Langmead, C. J. / Watson, J. / Wu, Z. et al. | 2010
- 3550
-
Synthesis and evaluation of novel a-amino cyclic boronates as inhibitors of HCV NS3 proteaseLi, X. / Zhang, Y. K. / Liu, Y. / Ding, C. Z. / Li, Q. / Zhou, Y. / Plattner, J. J. / Baker, S. J. / Qian, X. / Fan, D. et al. | 2010
- 3550
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Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 proteaseLi, Xianfeng / Zhang, Yong-Kang / Liu, Yang / Ding, Charles Z. / Li, Qun / Zhou, Yasheen / Plattner, Jacob J. / Baker, Stephen J. / Qian, Xuelei / Fan, Dazhong et al. | 2010
- 3557
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Orally bioavailable dual MMP-1/MMP-14 sparing, MMP-13 selective a-sulfone hydroxamatesKolodziej, S. A. / Hockerman, S. L. / Boehm, T. L. / Carroll, J. N. / DeCrescenzo, G. A. / McDonald, J. J. / Mischke, D. A. / Munie, G. E. / Fletcher, T. R. / Rico, J. G. et al. | 2010
- 3557
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Orally bioavailable dual MMP-1/MMP-14 sparing, MMP-13 selective α-sulfone hydroxamatesKolodziej, Stephen A. / Hockerman, Susan L. / Boehm, Terri L. / Carroll, Jeffery N. / DeCrescenzo, Gary A. / McDonald, Joseph J. / Mischke, Debbie A. / Munie, Grace E. / Fletcher, Theresa R. / Rico, Joseph G. et al. | 2010
- 3561
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MMP-13 selective isonipecotamide α-sulfone hydroxamatesKolodziej, Stephen A. / Hockerman, Susan L. / DeCrescenzo, Gary A. / McDonald, Joseph J. / Mischke, Debbie A. / Munie, Grace E. / Fletcher, Theresa R. / Stehle, Nathan / Swearingen, Craig / Becker, Daniel P. et al. | 2010
- 3561
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MMP-13 selective isonipecotamide a-sulfone hydroxamatesKolodziej, S. A. / Hockerman, S. L. / DeCrescenzo, G. A. / McDonald, J. J. / Mischke, D. A. / Munie, G. E. / Fletcher, T. R. / Stehle, N. / Swearingen, C. / Becker, D. P. et al. | 2010
- 3565
-
Synthesis and biological evaluation of azobicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetesCho, Tang Peng / Long, Yang Fang / Gang, Lin Zhi / Yang, Wang / Jun, Lu He / Yuan, Shen Guang / Hong, Fu Jian / Lin, Wang / Liang, Guan Dong / Lei, Zhang et al. | 2010
- 3569
-
Synthesis, docking studies, and evaluation of pyrimidines as inhibitors of SARS-CoV 3CL proteaseRamajayam, R. / Tan, Kian-Pin / Liu, Hun-Ge / Liang, Po-Huang et al. | 2010
- 3573
-
Structure–activity relationship (SAR) investigations of tetrahydroquinolines as BKCa agonistsGore, Vijay K. / Ma, Vu V. / Yin, Ruoyuan / Ligutti, Joe / Immke, David / Doherty, Elizabeth M. / Norman, Mark H. et al. | 2010
- 3579
-
5-Arylamino-1,2,4-triazin-6(1H)-one CRF1 receptor antagonistsSchmitz, William D. / Brenner, Allison B. / Bronson, Joanne J. / Ditta, Jonathan L. / Griffin, Corrine R. / Li, Yu-Wen / Lodge, Nicholas J. / Molski, Thaddeus F. / Olson, Richard E. / Zhuo, Xiaoliang et al. | 2010
- 3584
-
Quinlobelane: A water-soluble lobelane analogue and inhibitor of VMAT2Vartak, Ashish P. / Gabriela Deaciuc, A. / Dwoskin, Linda P. / Crooks, Peter A. et al. | 2010
- 3588
-
4,6-Dimethoxy-1,3,5-triazine oligoxyloglucans: Novel one-step preparable substrates for studying action of endo-β-1,4-glucanase III from Trichoderma reeseiKobayashi, Atsushi / Tanaka, Tomonari / Watanabe, Kazuhito / Ishihara, Masaki / Noguchi, Masato / Okada, Hirofumi / Morikawa, Yasushi / Shoda, Shin-ichiro et al. | 2010
- 3588
-
4,6-Dimethoxy-1,3,5-triazine oligoxyloglucans: Novel one-step preparable substrates for studying action of endo-b-1,4-glucanase III from Trichoderma reeseiKobayashi, A. / Tanaka, T. / Watanabe, K. / Ishihara, M. / Noguchi, M. / Okada, H. / Morikawa, Y. / Shoda, S. i. et al. | 2010
- 3592
-
Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitorsShi, Wei / Duan, Yuejiao / Qian, Yu / Li, Ming / Yang, Liping / Hu, Wenhao et al. | 2010
- 3596
-
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IVYeh, Teng-Kuang / Tsai, Ting-Yueh / Hsu, Tsu / Cheng, Jai-Hong / Chen, Xin / Song, Jen-Shin / Shy, Horng-Shing / Chiou, Mei-Chun / Chien, Chia-Hui / Tseng, Ya-Ju et al. | 2010
- 3601
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Carbonic anhydrase inhibitors: Crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I–XVDi Fiore, Anna / Monti, Simona Maria / Innocenti, Alessio / Winum, Jean-Yves / De Simone, Giuseppina / Supuran, Claudiu T. et al. | 2010
- 3606
-
Design, synthesis and evaluation of 2,4-disubstituted pyrimidines as cholinesterase inhibitorsMohamed, Tarek / Rao, Praveen P.N. et al. | 2010
- 3610
-
S-Aryltriazole acyclonucleosides: Synthesis and biological evaluation against hepatitis C virusLiu, Yang / Xia, Yi / Li, Wei / Cong, Mei / Maggiani, Alain / Leyssen, Pieter / Qu, Fanqi / Neyts, Johan / Peng, Ling et al. | 2010
- 3614
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Discovery of a novel series of CXCR3 antagonistsCrosignani, Stefano / Missotten, Marc / Cleva, Christophe / Dondi, Ruggero / Ratinaud, Yann / Humbert, Yves / Mandal, Ashis Baran / Bombrun, Agnès / Power, Christine / Chollet, André et al. | 2010
- 3618
-
Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonistsLucas, Brian S. / Aaron, Wade / An, Songzhu / Austin, Richard J. / Brown, Matthew / Chan, Hon / Chong, Angela / Hungate, Randall / Huang, Tom / Jiang, Ben et al. | 2010
- 3623
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New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitorsEsteves, M. Alexandra / Ortet, Osvaldo / Capelo, Anabela / Supuran, Claudiu T. / Marques, Sérgio M. / Santos, M. Amélia et al. | 2010
- 3628
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New pyrazolo[1,5a]pyrimidines as orally active inhibitors of LckGommermann, Nina / Buehlmayer, Peter / von Matt, Anette / Breitenstein, Werner / Masuya, Keiichi / Pirard, Bernard / Furet, Pascal / Cowan-Jacob, Sandra W. / Weckbecker, Gisbert et al. | 2010
- 3632
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Tricyclic sulfones as orally active g-secretase inhibitors: Synthesis and structure-activity relationship studiesSasikumar, T. K. / Qiang, L. / Burnett, D. A. / Cole, D. / Xu, R. / Li, H. / Greenlee, W. J. / Clader, J. / Zhang, L. / Hyde, L. et al. | 2010
- 3632
-
Tricyclic sulfones as orally active γ-secretase inhibitors: Synthesis and structure–activity relationship studiesSasikumar, T.K. / Qiang, Li / Burnett, Duane A. / Cole, David / Xu, Ruo / Li, Hongmei / Greenlee, William J. / Clader, John / Zhang, Lili / Hyde, Lynn et al. | 2010
- 3636
-
Syntheses and structure–activity relationship (SAR) studies of 2,5-diazabicyclo[2.2.1]heptanes as novel α7 neuronal nicotinic receptor (NNR) ligandsLi, Tao / Bunnelle, William H. / Ryther, Keith B. / Anderson, David J. / Malysz, John / Helfrich, Rosalind / Grønlien, Jens H. / Håkerud, Monika / Peters, Dan / Schrimpf, Michael R. et al. | 2010
- 3636
-
Syntheses and structure-activity relationship (SAR) studies of 2,5-diazabicyclo[2.2.1]heptanes as novel a7 neuronal nicotinic receptor (NNR) ligandsLi, T. / Bunnelle, W. H. / Ryther, K. B. / Anderson, D. J. / Malysz, J. / Helfrich, R. / Gronlien, J. H. / Hakerud, M. / Peters, D. / Schrimpf, M. R. et al. | 2010
- 3640
-
Synthesis and molecular modeling studies of 3-chloro-4-substituted-1-(8-hydroxy-quinolin-5-yl)-azetidin-2-ones as novel anti-filarial agentsChhajed, Santosh S. / Manisha, Puranik / Bastikar, Virupaksha A. / Animeshchandra, Haldar / Ingle, V.N. / Upasani, Chandrashekhar D. / Wazalwar, Sachin S. et al. | 2010
- 3645
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Tetracyclic sulfones as potent γ-secretase inhibitors: Synthesis and structure–activity relationship studiesSasikumar, T.K. / Burnett, Duane A. / Asberom, Theodros / Wu, Wen-Lian / Bennett, Chad / Cole, David / Xu, Ruo / Greenlee, William J. / Clader, John / Zhang, Lili et al. | 2010
- 3645
-
Tetracyclic sulfones as potent g-secretase inhibitors: Synthesis and structure-activity relationship studiesSasikumar, T. K. / Burnett, D. A. / Asberom, T. / Wu, W. L. / Bennett, C. / Cole, D. / Xu, R. / Greenlee, W. J. / Clader, J. / Zhang, L. et al. | 2010
- 3649
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Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitorsPayne, Sara L. / Rodriguez-Aristegui, Sonsoles / Bardos, Julia / Cano, Céline / Golding, Bernard T. / Hardcastle, Ian R. / Peacock, Marcus / Parveen, Nahida / Griffin, Roger J. et al. | 2010
- 3654
-
Synthesis and in vivo evaluation of [11C]MPTQ: A potential PET tracer for alpha2A-adrenergic receptorsPrabhakaran, Jaya / Majo, Vattoly J. / Milak, Matthew S. / Mali, Pratap / Savenkova, Lyudmila / Mann, J. John / Parsey, Ramin V. / Kumar, J.S. Dileep et al. | 2010
- 3658
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Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteriaPruksakorn, Patamaporn / Arai, Masayoshi / Kotoku, Naoyuki / Vilchèze, Catherine / Baughn, Anthony D. / Moodley, Prashini / Jacobs, William R. Jr. / Kobayashi, Motomasa et al. | 2010
- 3664
-
Facile and efficient aromatization of 1,4-dihydropyridines with M(NO3)2·XH2O, TNCB, TBAP and HMTAI and preparation of deuterium labeled dehydronifedipine from nifedipine-d3Shaikh, Ajam C. / Chen, Chinpiao et al. | 2010
- 3669
-
Discovery of 6-chloro-2-trifluoromethyl-7-aryl-7H-imidazo[1,2-a]imidazol-3-ylmethylamines, a novel class of corticotropin-releasing factor receptor type 1 (CRF1R) antagonistsZuev, Dmitry / Vrudhula, Vivekananda M. / Michne, Jodi A. / Dasgupta, Bireshwar / Pin, Sokhom S. / Huang, Xiaohua Stella / Wu, Dedong / Gao, Qi / Zhang, Jie / Taber, Matthew T. et al. | 2010
- 3675
-
Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screeningCai, Haiyan / Yan, Guirui / Zhang, Xiaodong / Gorbenko, Olena / Wang, Heyao / Zhu, Weiliang et al. | 2010
- 3680
-
Hybrid liposomes inhibit the growth of Cholangiocarcinoma by induction of cell cycle arrest in G1 phaseTowata, Tomomi / Komizu, Yuji / Kariya, Ryusho / Suzu, Shinya / Matsumoto, Yoko / Kobayashi, Naoya / Wongkham, Chaisiri / Wongkham, Sopit / Ueoka, Ryuichi / Okada, Seiji et al. | 2010
- 3683
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In silico characterization of cytisinoids docked into an acetylcholine binding proteinAbin-Carriquiry, Juan Andrés / Zunini, Margot Paulino / Cassels, Bruce K. / Wonnacott, Susan / Dajas, Federico et al. | 2010
- 3688
-
Regiospecific and conformationally restrained analogs of melphalan and dl-2-NAM-7 and their affinities for the large neutral amino acid transporter (system LAT1) of the blood–brain barrierMatharu, Jyothi / Oki, Jun / Worthen, David R. / Smith, Quentin R. / Crooks, Peter A. et al. | 2010
- 3692
-
Interaction of heterocyclic thiols/thiones eliminated from cephalosporins with iodine and its biological implicationsTamilselvi, A. / Mugesh, Govindasamy et al. | 2010
- 3698
-
Synthesis of novel β-lactam fused spiroisoxazolidine chromanones and tetralones as potent antimicrobial agent for human and plant pathogensArumugam, Natarajan / Raghunathan, Raghavachary / Shanmugaiah, Vellaisamy / Mathivanan, Narayanasamy et al. | 2010
- 3698
-
Synthesis of novel b-lactam fused spiroisoxazolidine chromanones and tetralones as potent antimicrobial agent for human and plant pathogensArumugam, N. / Raghunathan, R. / Shanmugaiah, V. / Mathivanan, N. et al. | 2010
- 3703
-
Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase methodKowalski, Jennifer A. / Swinamer, Alan D. / Muegge, Ingo / Eldrup, Anne B. / Kukulka, Alison / Cywin, Charles L. / De Lombaert, Stéphane et al. | 2010
- 3708
-
Non-basic ligands for aminergic GPCRs: The discovery and development diaryl sulfones as selective, orally bioavailable 5-HT2A receptor antagonists for the treatment of sleep disordersLadduwahetty, Tammy / Gilligan, Myra / Humphries, Alexander / Merchant, Kevin J. / Fish, Rebecca / McAlister, George / Ivarsson, Magnus / Dominguez, Maria / O’Connor, Desmond / MacLeod, Angus M. et al. | 2010
- 3713
-
The discovery and SAR of indoline-3-carboxamides—A new series of 5-HT6 antagonistsReid, Mark / Carlyle, Ian / Caulfield, Wilson L. / Clarkson, Tom R. / Cusick, Fiona / Epemolu, Ola / Gilfillan, Robert / Goodwin, Richard / Jaap, David / O’Donnell, Elise C. et al. | 2010
- 3717
-
Prenylcoumarin with Rev-export inhibitory activity from Cnidii Monnieris FructusTamura, Satoru / Fujitani, Toshiaki / Kaneko, Masafumi / Murakami, Nobutoshi et al. | 2010
- 3721
-
Synthesis, analgesic and anti-inflammatory activities of some novel pyrazolines derivativesJoshi, Ratnadeep S. / Mandhane, Priyanka G. / Diwakar, Santosh D. / Dabhade, Sanjay K. / Gill, Charansingh H. et al. | 2010
- 3726
-
Investigation of Beckett–Casy model 2: Synthesis of novel 15–16 nornaltrexone derivatives and their pharmacologyNagase, Hiroshi / Imaide, Satomi / Tomatsu, Miyuki / Nemoto, Toru / Nakajima, Mayumi / Nakao, Kaoru / Mochizuki, Hidenori / Fujii, Hideaki et al. | 2010
- 3730
-
Looking for a 5-HT7 radiotracer for positron emission tomographyAndriès, Julien / Lemoine, Laëtitia / Mouchel-Blaisot, Alice / Tang, Sandrine / Verdurand, Mathieu / Le Bars, Didier / Zimmer, Luc / Billard, Thierry et al. | 2010
- 3734
-
Structure-based prediction and biosynthesis of the major mammalian metabolite of the cardioactive prototype LASSBio-294Carneiro, Emmanuel O. / Andrade, Carolina H. / Braga, Rodolpho C. / Tôrres, Andréa C.B. / Alves, Rosângela O. / Lião, Luciano M. / Fraga, Carlos A.M. / Barreiro, Eliezer J. / Oliveira, Valéria de et al. | 2010
- 3737
-
Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMsWágner, Gábor / Wéber, Csaba / Nyéki, Olga / Nógrádi, Katalin / Bielik, Attila / Molnár, László / Bobok, Amrita / Horváth, Attila / Kiss, Béla / Kolok, Sándor et al. | 2010
- 3742
-
Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonistsCrombie, Aimee L. / Antrilli, Thomas M. / Campbell, Brandon A. / Crandall, David L. / Failli, Amedeo A. / He, Yanan / Kern, Jeffrey C. / Moore, William J. / Nogle, Lisa M. / Trybulski, Eugene J. et al. | 2010
- 3746
-
Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 3, aryl substituted pyrrolidinesBosanac, Todd / Hickey, Eugene R. / Ginn, John / Kashem, Mohammed / Kerr, Steven / Kugler, Stanley / Li, Xiang / Olague, Alan / Schlyer, Sabine / Young, Erick R.R. et al. | 2010
- 3750
-
Dihydro-pyrano[2,3-b]pyridines and tetrahydro-1,8-naphthyridines as CB1 receptor inverse agonists: Synthesis, SAR and biological evaluationMadsen-Duggan, Christina B. / Debenham, John S. / Walsh, Thomas F. / Yan, Lin / Huo, Pei / Wang, Junying / Tong, Xinchun / Lao, Julie / Fong, Tung M. / Xiao, Jing Chen et al. | 2010
- 3755
-
Synthesis and biological activity of oxadiazole and triazolothiadiazole derivatives as tyrosinase inhibitorsLam, Kok Wai / Syahida, Ahmad / Ul-Haq, Zaheer / Rahman, Mohd. Basyaruddin Abdul / Lajis, Nordin H. et al. | 2010
- 3760
-
Discovery of 4-{1-[({1-[4-(trifluoromethyl)benzyl]-1H-indol-7-yl}carbonyl)amino]cyclopropyl}benzoic acid (MF-766), a highly potent and selective EP4 antagonist for treating inflammatory painColucci, John / Boyd, Michael / Berthelette, Carl / Chiasson, Jean-Francois / Wang, Zhaoyin / Ducharme, Yves / Friesen, Rick / Wrona, Mark / Levesque, Jean-Francois / Denis, Danielle et al. | 2010
- 3764
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New estrogenic compounds isolated from Broussonetia kazinokiLee, Da Yeon / Kim, Do Hee / Lee, Hwa Jin / Lee, YoungJoo / Ryu, Kwang Hee / Jung, Bo-In / Song, Yun Seon / Ryu, Jae-Ha et al. | 2010
- 3768
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Synthetic studies on selective adenosine A2A receptor antagonists. Part II: Synthesis and structure–activity relationships of novel benzofuran derivativesSaku, Osamu / Saki, Mayumi / Kurokawa, Masako / Ikeda, Ken / Uchida, Shin-ichi / Takizawa, Takuya / Uesaka, Noriaki et al. | 2010
- 3772
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Novel trivalent anti-influenza reagentFeng, Fei / Miura, Nobuaki / Isoda, Norikazu / Sakoda, Yoshihiro / Okamatsu, Masatoshi / Kida, Hiroshi / Nishimura, Shin-Ichiro et al. | 2010
- 3777
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First synthesis and antiprotozoal activities of divinyl sulfone-modified carbohydratesPal, Tarun Kumar / Dey, Tuli / Chakrabarty, Arindam / Dey, Debanjana / Ghosh, Sudip K. / Pathak, Tanmaya et al. | 2010
- 3781
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Synthesis and biological evaluation of a novel 99mTc(CO)3 complex of ciprofloxacin dithiocarbamate as a potential agent to target infectionZhang, Junbo / Zhang, Shijian / Guo, Haixun / Wang, Xuebin et al. | 2010
- 3785
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Phenanthrenes from Dendrobium nobile and their inhibition of the LPS-induced production of nitric oxide in macrophage RAW 264.7 cellsHwang, Ji Sang / Lee, Seon A / Hong, Seong Su / Han, Xiang Hua / Lee, Chul / Kang, Shin Jung / Lee, Dongho / Kim, Youngsoo / Hong, Jin Tae / Lee, Mi Kyeong et al. | 2010
- 3788
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Second generation N-(1,2-diphenylethyl)piperazines as dual serotonin and noradrenaline reuptake inhibitors: Improving metabolic stability and reducing ion channel activityFray, M. Jonathan / Fish, Paul V. / Allan, Gillian A. / Bish, Gerwyn / Clarke, Nick / Eccles, Rachel / Harrison, Anthony C. / Net, Jean-Loic Le / Phillips, Stephen C. / Regan, Nicola et al. | 2010
- 3793
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Evolution of specific RNA motifs derived from pan-protein interacting precursorsAhmed, Marie-Sophie L. / Mayer, Günter et al. | 2010
- 3797
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Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteriaBunders, Cynthia A. / Richards, Justin J. / Melander, Christian et al. | 2010
- 3801
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Investigation of Beckett–Casy model 3: Synthesis of novel naltrexone derivatives with contracted and expanded D-rings and their pharmacologyNagase, Hiroshi / Imaide, Satomi / Tomatsu, Miyuki / Hirayama, Shigeto / Nemoto, Toru / Sato, Noriko / Nakajima, Mayumi / Nakao, Kaoru / Mochizuki, Hidenori / Gouda, Hiroaki et al. | 2010
- 3805
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1,4-Dihydropyrazolo[4,3-d]imidazole phenyl derivatives: A novel type II Raf kinase inhibitorsYu, Hana / Jung, Yunkyung / Kim, Hwan / Lee, Junghun / Oh, Chang-Hyun / Yoo, Kyung Ho / Sim, Taebo / Hah, Jung-Mi et al. | 2010
- 3809
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New aminopropandiol derivatives as orally available and short-acting calcium-sensing receptor antagonistsShinagawa, Yuko / Inoue, Teruhiko / Hirata, Kazuyuki / Katsushima, Takeo / Nakagawa, Takashi / Matsuo, Yushi / Shindo, Masanori / Hashimoto, Hiromasa et al. | 2010
- 3814
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Total synthesis of (±)-elegansidiol, (±)-farnesiferol B, and (±)-farnesiferol DYadav, Jhillu Singh / Satyanarayana, Kamani / Sreedhar, Pamu / Srihari, Pabbaraja / Shaik, Thokhir Basha / Kalivendi, Shasi Vardhan et al. | 2010
- 3818
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The oxidation of 8-oxo-7,8-dihydroguanine by iodineKino, Katsuhito / Morikawa, Masayuki / Kobayashi, Teruhiko / Kobayashi, Takanobu / Komori, Rie / Sei, Yoshihisa / Miyazawa, Hiroshi et al. | 2010
- 3821
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Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKb inhibitorsCrombie, A. L. / Sum, F. W. / Powell, D. W. / Hopper, D. W. / Torres, N. / Berger, D. M. / Zhang, Y. / Gavriil, M. / Sadler, T. M. / Arndt, K. et al. | 2010
- 3821
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Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKβ inhibitorsCrombie, Aimee L. / Sum, Fuk-Wah / Powell, Dennis W. / Hopper, Darrin W. / Torres, Nancy / Berger, Dan M. / Zhang, Yixian / Gavriil, Maria / Sadler, Tammy M. / Arndt, Kim et al. | 2010
- 3826
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Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer propertiesKicha, Alla A. / Ivanchina, Natalia V. / Huong, Trinh T.T. / Kalinovsky, Anatoly I. / Dmitrenok, Pavel S. / Fedorov, Sergey N. / Dyshlovoy, Sergey A. / Long, Pham Q. / Stonik, Valentin A. et al. | 2010
- 3831
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Syntheses and biological evaluation of ring-C modified colchicine analogsYang, Baiyuan / Zhu, Zhiqing C. / Goodson, Holly V. / Miller, Marvin J. et al. | 2010
- 3834
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Corrigendum to “Discovery of the first known small-molecule inhibitors of heme-regulated eukaryotic initiation factor 2α (HRI) kinase” [Bioorg. Med. Chem. Lett. 19 (2009) 6548]Rosen, Mark D. / Woods, Craig R. / Goldberg, Steven D. / Hack, Michael D. / Dawn Bounds, A. / Yang, Young / Wagaman, Pamela C. / Phuong, Victor K. / Ameriks, Angela P. / Barrett, Terrance D. et al. | 2010
- 3834
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Corrigendum to "Discovery of the first known small-molecule inhibitors of heme-regulated eukaryotic initiation factor 2a (HRI) kinase" [Bioorg. Med. Chem. Lett. 19 (2009) 6548]Rosen, M. D. / Woods, C. R. / Goldberg, S. D. / Hack, M. D. / Dawn Bounds, A. / Yang, Y. / Wagaman, P. C. / Phuong, V. K. / Ameriks, A. P. / Barrett, T. D. et al. | 2010
- IFC
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Editorial board| 2010