Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s disease (English)
- New search for: Velueta-Viveros, Martha
- Further information on Velueta-Viveros, Martha:
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- New search for: Puerta, Adrián
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- New search for: Fernandes, Miguel X.
- New search for: Moreno-Vargas, Antonio J.
- New search for: Padrón, José M.
- Further information on Padrón, José M.:
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- New search for: López, Óscar
- New search for: Fernández-Bolaños, José G.
- New search for: Velueta-Viveros, Martha
- New search for: Martínez-Bailén, Macarena
- New search for: Puerta, Adrián
- New search for: Romero-Hernández, Laura L.
- New search for: Křen, Vladimír
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- New search for: Fernández-Bolaños, José G.
In:
Bioorganic Chemistry
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127
;
2022
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s disease
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Contributors:Velueta-Viveros, Martha ( author ) / Martínez-Bailén, Macarena ( author ) / Puerta, Adrián ( author ) / Romero-Hernández, Laura L. ( author ) / Křen, Vladimír ( author ) / Merino-Montiel, Penélope ( author ) / Montiel-Smith, Sara ( author ) / Fernandes, Miguel X. ( author ) / Moreno-Vargas, Antonio J. ( author ) / Padrón, José M. ( author )
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Published in:Bioorganic Chemistry ; 127
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Publisher:
- New search for: Elsevier Inc.
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Publication date:2022-06-21
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 127
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
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Nanotechnology applications for treatment of hepatic infections via modulating Hepatic histopathological and DNA alterationsGad, Sameh S. / Abdelrahim, Dina S. / Ismail, Sameh H. / Ibrahim, Sherine M. et al. | 2022
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Design, synthesis and biological evaluation of N-(4-alkoxy-3-(1H-tetrazol-1-yl)phenyl) heterocyclic aromatic amide derivatives as xanthine oxidase inhibitorsZhang, Ting-jian / Zhang, Zhen-hao / Zhang, Xu / Wang, Zhao-ran / Xu, En-yu / Tu, Shun / Zhang, Yi / Meng, Fan-hao et al. | 2022
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New dihydrobenzoxanthone derivatives with bacterial neuraminidase inhibitory activity isolated from Artocarpus elasticusBaiseitova, Aizhamal / Lee, Gihwan / Shah, Abdul Bari / Yoon, Sanghwa / Kim, Jeong Ho / Lee, Yong Hyun / Park, Ki Hun et al. | 2022
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From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-κB inhibitorsWagdy, Reem A. / Chen, Po-Jen / Hamed, Mostafa M. / Darwish, Sarah S. / Chen, Shun-Hua / Abadi, Ashraf H. / Abdel-Halim, Mohammad / Hwang, Tsong-Long / Engel, Matthias et al. | 2022
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Cadinane-type sesquiterpenoid dimeric diastereomers hibisceusones A-C from infected stems of Hibiscus tiliaceus with cytotoxic activity against triple-negative breast cancer cellsChen, De-Li / Ma, Guo-Xu / Yang, Er-Lan / Yang, Yun / Wang, Can-Hong / Sun, Zhao-Cui / Liang, Han-Qiao / Xu, Xu-Dong / Wei, Jian-He et al. | 2022
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Synthesis of the new nucleoside 5′-alpha-iminophosphates using Staudinger reactionVasilyeva, Svetlana V. / Kuznetsova, Alexandra A. / Baranovskaya, Elizaveta E. / Kuznetsov, Nikita A. / Lomzov, Alexander A. / Pyshnyi, Dmitrii V. et al. | 2022
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A novel ratiometric fluorescent probe for the detection and imaging of cysteine in living cellsZheng, Cheng / Zhou, Xiaoqin / Wang, Huizhe / Ji, Min / Wang, Peng et al. | 2022
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Antidiabetic lanostane triterpenoids from the fruiting bodies of Ganoderma weberianumYang, Li / Kong, De-Xian / Xiao, Na / Ma, Qing-Yun / Xie, Qing-Yi / Guo, Jiao-Cen / Ying Deng, Chun / Ma, Hai-Xia / Hua, Yan / Dai, Hao-Fu et al. | 2022
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Further studies on C2′-substituted 1-phenylbenzazepines as dopamine D1 receptor ligandsGiri, Rajan / Namballa, Hari K. / Sarker, Ananta / Alberts, Ian / Harding, Wayne W. et al. | 2022
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Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophoresYamali, Cem / Sakagami, Hiroshi / Satoh, Keitaro / Bandow, Kenjiro / Uesawa, Yoshihiro / Bua, Silvia / Angeli, Andrea / Supuran, Claudiu T. / Gul, Halise Inci et al. | 2022
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Recent developments in promiscuous enzymatic reactions for carbon–nitrogen bond formationXia, Hui / Song, Jinsong / Li, Changfan / Xue, Feng et al. | 2022
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Heterocyclic ring expansion yields anthraquinone derivatives potent against multidrug resistant tumor cellsTikhomirov, Alexander S. / Tsvetkov, Vladimir B. / Volodina, Yulia L. / Litvinova, Valeria A. / Andreeva, Daria V. / Dezhenkova, Lyubov G. / Kaluzhny, Dmitry N. / Treshalin, Ivan D. / Shtil, Alexander A. / Shchekotikhin, Andrey E. et al. | 2022
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Structurally diverse metabolites from a soil-derived fungus Aspergillus calidoustusLi, Fengli / Mo, Shuyuan / Yin, Jie / Zhang, Sitian / Gu, Saisai / Ye, Zi / Wang, Jianping / Hu, Zhengxi / Zhang, Yonghui et al. | 2022
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Development of a series of novel Mcl-1 inhibitors bearing an indole carboxylic acid moietyDeng, Hongguang / Huang, Min / Liu, Hui / Zhang, Hong / Liu, Liang / Gao, Bensheng / Li, Xianlu / Li, Jinbo / Niu, Qun / Zhang, Zhenwei et al. | 2022
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Discovery and evaluation of cytisine N-isoflavones as novel EGFR/HER2 dual inhibitorsWang, Yanqing / Yin, Xiaoying / Chen, Lingyan / Yin, Zhixiang / Zuo, Zhicheng et al. | 2022
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Genus Thermotoga: A valuable home of multifunctional glycoside hydrolases (GHs) for industrial sustainabilityAkram, Fatima / Haq, Ikram ul / Shah, Fatima Iftikhar / Aqeel, Amna / Ahmed, Zeeshan / Mir, Azka Shahzad / Qureshi, Sumbal Sajid / Raja, Saleha Ibadat et al. | 2022
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Six pairs of enantiomeric phthalide dimers from the rhizomes of Ligusticum chuanxiong and their absolute configurations and anti-inflammatory activitiesHuang, Lu / Peng, Cheng / Guo, Li / Feng, Rui / Shu, Hong-Zhen / Tian, Yun-Cai / Zhou, Qin-Mei / Xiong, Liang et al. | 2022
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Investigation on the potential targets of Astragaloside IV against intracerebral hemorrhage based on network pharmacology and experimental validationZheng, Yingyi / Li, Ruoqi / Zhou, Yuan / Zhang, Shanshan / Fan, Xiang et al. | 2022
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Structure-activity relationship analysis of novel GSPT1 degraders based on benzotriazinone scaffold and its antitumor effect on xenograft mouse modelTakwale, Akshay D. / Kim, Eun Yeong / Jang, Yerin / Lee, Dong Ho / Kim, Seulgi / Choi, Yuri / Kim, Jin Hwan / Lee, Da Yeon / Kim, Yeongrin / Lee, So Myoung et al. | 2022
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Rational drug design strategies for the development of promising multi-target directed indole hybrids as Anti-Alzheimer agentsGeorge, Namy / Jawaid Akhtar, Md. / Al Balushi, Khalid A. / Alam Khan, Shah et al. | 2022
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Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cellGong, Xiaobao / He, Yutong / Yang, Dailin / Yang, Shun / Li, Jinke / Zhao, Huaxin / Chen, Qianfeng / Ren, Qiao / Zhang, Baoshun et al. | 2022
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Isolation, derivatization, in-vitro, and in-silico studies of potent butyrylcholinesterase inhibitors from Berberis parkeriana SchneidAli, Rabia / Atia-tul-Wahab / Wajid, Sheeba / Khan, Maria Aqeel / Yousuf, Sammer / Shaikh, Muniza / Hassan Laghari, Gul / Rahman, Atta-ur / Choudhary, M. Iqbal et al. | 2022
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Biocatalytic hydrogen-transfer to access enantiomerically pure proxyphylline, xanthinol, and diprophyllineBorowiecki, Paweł / Rudzka, Aleksandra / Reiter, Tamara / Kroutil, Wolfgang et al. | 2022
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The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, VEGFR-2, and cell cycle of myeloid leukemiaOthman, Esraa M. / Fayed, Eman A. / Husseiny, Ebtehal M. / Abulkhair, Hamada S. et al. | 2022
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Design, synthesis, in vitro, and in silico enzymatic evaluations of thieno[2,3-b]quinoline-hydrazones as novel inhibitors for α-glucosidaseNoori, Milad / Rastak, Mryam / Halimi, Mohammad / Ghomi, Minoo Khalili / Mollazadeh, Mrjan / Mohammadi-Khanaposhtani, Maryam / Sayahi, Mohammad Hosein / Rezaei, Zahra / Mojtabavi, Somayeh / Ali Faramarzi, Mohammad et al. | 2022
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Synthesis of novel 4,7-disubstituted quinoline derivatives as autophagy inducing agents via targeting stabilization of ATG5Li, Xiangpan / Chen, Qing / Ao, Jingsheng / Lin, Wenxin / Qiu, Liqin / Cao, Rihui et al. | 2022
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Hexa-substituted cyclotriphosphazene derivatives containing hetero-ring chalcones: Synthesis, in vitro cytotoxic activity and their DNA damage determinationBeytur, Asiye / Tekin, Çiğdem / Çalışkan, Eray / Tekin, Suat / Koran, Kenan / Orhan Görgülü, Ahmet / Sandal, Süleyman et al. | 2022
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Diverse polycyclic polyprenylated acylphloroglucinols with anti-neuroinflammatory activity from Hypericum beaniiLi, Ya-Wei / Lu, Wei-Jia / Zhou, Xin / Zhang, Chao / Li, Xue-Yan / Tang, Peng-Fei / Kong, Ling-Yi / Xu, Wen-Jun et al. | 2022
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[11]-chaetoglobosins with cytotoxic activities from Pseudeurotium bakeriDuan, Fangfang / Gao, Ying / Peng, Xiaogang / Meng, Xianggao / Chang, Jinling / Gan, Yutian / Ouyang, Qianxi / Ruan, Hanli et al. | 2022
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An insight into the interaction between Indisulam and human serum albumin: Spectroscopic method, computer simulation and in vitro cytotoxicity assayZhou, Bijia / Zhou, Hui / Xu, Linlin / Cai, Ruirui / Chen, Chaolan / Chi, Baozhu / Tuo, Xun et al. | 2022
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Imidazo[4,5-b]pyridine derived tubulin polymerization inhibitors: Design, synthesis, biological activity in vitro and computational analysisBoček, Ida / Hok, Lucija / Persoons, Leentje / Daelemans, Dirk / Vianello, Robert / Hranjec, Marijana et al. | 2022
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Synthesis, biological evaluation and molecular docking studies of novel diosgenin derivatives as anti-inflammatory agentsZhang, Sheng-Nan / Mu, Xiao-Dong / Zhang, Xiao-Fan / Luan, Ming-Zhu / Ma, Guang-Qun / Li, Wei / Meng, Qing-Guo / Chai, Xiao-Yun / Hou, Gui-Ge et al. | 2022
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Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cellsdel Rosario, Henoc / Saavedra, Ester / Brouard, Ignacio / González-Santana, Daniel / García, Celina / Spínola-Lasso, Elena / Tabraue, Carlos / Quintana, José / Estévez, Francisco et al. | 2022
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Dihydroxyphenyl-substituted thiosemicarbazone: A potent scaffold for the development of metallo-β-lactamases inhibitors and antimicrobialLiu, Lu / Xu, Yin-Sui / Chigan, Jia-Zhu / Zhai, Le / Ding, Huan-Huan / Wu, Xiao-Rong / Chen, Wei-Ya / Yang, Ke-Wu et al. | 2022
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New benzimidazole based hybrids: Synthesis, molecular modeling study and anticancer evaluation as TopoII inhibitorsNawareg, Nareman A. / Mostafa, Amany S. / El-Messery, Shahenda M. / Nasr, Magda N.A. et al. | 2022
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SAR study culminates in a series of HDAC6 selective inhibitors featuring Schisandrin C-analogous Cap as potential immunomodulatory agents for cancer therapyTao, Qiangqiang / Wei, Wei / Lv, Xiaoqing / Guo, Jian / Tao, Yaotian / Zhang, Mingming / He, Ge / Li, Zhi / Gui, Shuangying / Ma, Xiaodong et al. | 2022
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Discovery of a novel class of benzoxazole derivatives as histamine H3 receptor ligands for the treatment of neuropathic painLi, Ziying / Xiao, Xinyi / Xue, Yulin / Zhou, Huiling / Huang, Chaonan / Zhu, Mo / Zhuang, Tao / Chen, Yin / Huang, Ling et al. | 2022
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Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s diseaseVelueta-Viveros, Martha / Martínez-Bailén, Macarena / Puerta, Adrián / Romero-Hernández, Laura L. / Křen, Vladimír / Merino-Montiel, Penélope / Montiel-Smith, Sara / Fernandes, Miguel X. / Moreno-Vargas, Antonio J. / Padrón, José M. et al. | 2022
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Discovery of carbamate-based N-salicyloyl tryptamine derivatives as novel pleiotropic agents for the treatment of Alzheimer's diseaseWang, Yuying / Zhang, Honghua / Liu, Dan / Li, Xuelin / Long, Lin / Peng, Ying / Qi, Fujian / Wang, Yuqing / Jiang, Weifan / Wang, Zhen et al. | 2022
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Brujavanoids A–U, structurally diverse apotirucallane-type triterpenoids from Brucea javanica and their anti-inflammatory effectsHu, Zhuo-Fan / Su, Jun-Cheng / Sun, Xing / Xia, Ru-Feng / Wu, Jia-Le / Fu, Xiao-Na / Zhang, Bing-Zhu / Chen, Jia-Chun / Wan, Luo-Sheng et al. | 2022
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Cucurbitane triterpenoid entities derived from Hemsleya penxianensis triggered glioma cell apoptosis via ER stress and MAPK signalling cross-talkLi, Zongyang / Chen, Meiying / Chen, Fanfan / Li, Weiping / Huang, Guodong / Xu, Xudong / Wang, Sicen / Ma, Guoxu / Cui, Ping et al. | 2022
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A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphomaYao, Si / Yin, Jie / Liu, Wen / Li, Yang / Huang, Jianzheng / Qi, Changxing / Hu, Zhengxi / Tong, Qingyi / Gu, Lianghu / Zhang, Yonghui et al. | 2022
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Synthesis and biological evaluation of antibacterial activity of novel clarithromycin derivatives incorporating 1,2,3-triazole moieties at the 4″- and 11-OH positionsQin, Yinhui / Sun, Min / Zhang, Na / Yang, Yan / Ma, Peizhi et al. | 2022
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Flavone-1,2,3-triazole derivatives as potential α-glucosidase inhibitors: Synthesis, enzyme inhibition, kinetic analysis and molecular docking studyDhameja, Manoj / Kumar, Hariom / Kurella, Sirisha / Uma, Adepally / Gupta, Preeti et al. | 2022
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Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitorsLi, Wen / Zhang, Cheng / Zhang, Hong-en / Dong, Ru / Liu, Jing-ying / Wang, Chun-meng / Wang, Min / Wang, Yu-wei / Wang, Chao / Zhang, Yan et al. | 2022
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Twelve novel sesquiterpenes with anti-inflammatory and cholesterol-lowering activities from burdock leavesLiang, Hanjing / Feng, Qingmei / Guo, Hui / Lv, Jiangnan / Zhang, Lingxia / Li, Qingxia / Chi, Jun / Liu, Qiuyan / Wang, Zhimin / Dai, Liping et al. | 2022
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Design, synthesis and biological evaluation of a series of novel pyrrolo[2,3-d]pyrimidin/pyrazolo[3,4-d]pyrimidin-4-amine derivatives as FGFRs-dominant multi-target receptor tyrosine kinase inhibitors for the treatment of gastric cancerWu, Xiuli / Liu, Zhihao / Gan, Cailin / Wei, Wei / Zhang, Qianyu / Liu, Hongyao / Que, Hanyun / Su, Xingping / Yue, Lin / He, Hualong et al. | 2022
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Discovery of novel 4-arylamino-quinazoline derivatives as EGFRL858R/T790M inhibitors with the potential to inhibit the non-small cell lung cancersGan, Wenhui / Wang, Caolin / Pan, Qingshan / Li, Yuzhen / Guo, Yuping / Fan, Dang / Peng, Yuting / Rao, Zixuan / Xu, Shan / Zheng, Pengwu et al. | 2022
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Styryl dyes with N-Methylpiperazine and N-Phenylpiperazine Functionality: AT-DNA and G-quadruplex binding ligands and theranostic agentsZonjić, Iva / Radić Stojković, Marijana / Crnolatac, Ivo / Tomašić Paić, Ana / Pšeničnik, Silvia / Vasilev, Aleksey / Kandinska, Meglena / Mondeshki, Mihail / Baluschev, Stanislav / Landfester, Katharina et al. | 2022
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Issue TOC| 2022
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Editorial Board| 2022
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Discovery of benzamide derivatives containing urea moiety as soluble epoxide hydrolase inhibitorsTian, Ye / Li, Shuo / Dong, Kuan / Su, Xiaolu / Fu, Siyu / Lv, Xuening / Duan, Meibo / Yang, Ting / Han, Yu / Hu, Guangda et al. | 2022
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New phthalimide-based derivatives as EGFR-TK inhibitors: Synthesis, biological evaluation, and molecular modeling studyMansour, Nayera I. / El-Sayed, Selwan M. / El-Gohary, Nadia S. / Abdel-Aziz, Naglaa I. / El-Subbagh, Hussein I. / Ghaly, Mariam A. et al. | 2022
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Scopariusicides D–M, ent-clerodane-based isomeric meroditerpenoids with a cyclobutane-fused γ/δ-lactone core from Isodon scopariusLi, Xing-Ren / Hu, Kun / Yan, Bing-Chao / Li, Xiao-Nian / Sun, Han-Dong / Liu, Yang / Puno, Pema-Tenzin et al. | 2022
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One pot domino synthesis of new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazine-2-thiones (THTTs) as anti-inflammatory and antinociceptive candidates: A proof from in-vivo to in-vitro and in-silico mechanistic studiesRaheem, Sumaya / Khan, Rasool / Pan, Xiandao / Ullah, Rahim / Ahsan Halim, Sobia / Khan, Ajmal / Al-Harrasi, Ahmed et al. | 2022
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Evaluation of the cell permeability of bicyclic peptoids and bicyclic peptide-peptoid hybridsWang, Hee Myeong / Seo, Chang Deok / Lee, Kang Ju / Park, Jun Hyung / Lim, Hyun-Suk et al. | 2022
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Corrigendum to “Design, synthesis, and biological evaluation of thiazole bioisosteres of goniofufurone through in vitro antiproliferative activity and in vivo toxicity” [Bioorg. Chem. 121 (2022) 105691]Svirčev, Miloš / Popsavin, Mirjana / Pavić, Aleksandar / Vasiljević, Branka / Rodić, Marko V. / Djokić, Sanja / Kesić, Jelena / Srećo Zelenović, Bojana / Popsavin, Velimir / Kojić, Vesna et al. | 2022