Explore the interaction mechanism between zein and EGCG using multi-spectroscopy and molecular dynamics simulation methods (English)
- New search for: Liu, Chengzhi
- New search for: Lv, Nan
- New search for: Ren, Gerui
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- New search for: Wang, Binju
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- New search for: Xie, Hujun
- Further information on Xie, Hujun:
- https://orcid.org/0000-0002-0035-2634
- New search for: Liu, Chengzhi
- New search for: Lv, Nan
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In:
Food Hydrocolloids
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120
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2021
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Explore the interaction mechanism between zein and EGCG using multi-spectroscopy and molecular dynamics simulation methods
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Contributors:Liu, Chengzhi ( author ) / Lv, Nan ( author ) / Ren, Gerui ( author ) / Wu, Ruibo ( author ) / Wang, Binju ( author ) / Cao, Zexing ( author ) / Xie, Hujun ( author )
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Published in:Food Hydrocolloids ; 120
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Publisher:
- New search for: Elsevier Ltd
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Publication date:2021-05-20
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 120
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
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Apparent universality of leguminous proteins in swelling and fibre formation when mixed with glutenCornet, Steven H.V. / Bühler, Jan M. / Gonçalves, Raquel / Bruins, Marieke E. / van der Sman, Ruud G.M. / van der Goot, Atze Jan et al. | 2021
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Carboxymethylpachymaran/alginate gel entrapping of natural pollen capsules for the encapsulation, protection and delivery of probiotics with enhanced viabilityDeng, Ziyu / Li, Jing / Song, Rong / Zhou, Bin / Li, Bin / Liang, Hongshan et al. | 2021
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Role of lysozyme on liquid egg white foaming properties: Interface behavior, physicochemical characteristics and protein structureZhao, Qiannan / Ding, Lixian / Xia, Minquan / Huang, Xi / Isobe, Kazuhiro / Handa, Akihiro / Cai, Zhaoxia et al. | 2021
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A novel starch from lotus (Nelumbo nucifera) seeds: Composition, structure, properties and modificationsChen, Chuanjie / Li, Guantian / Zhu, Fan et al. | 2021
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Protein gel shrinkage during solvent exchange: Quantification of gel compaction, mass transfer and compressive strengthDirauf, Martin P. / Hajnal, Anja / Gurikov, Pavel / Braeuer, Andreas S. et al. | 2021
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New insight into starch retrogradation: The effect of short-range molecular order in gelatinized starchHuang, Shiqing / Chao, Chen / Yu, Jinglin / Copeland, Les / Wang, Shujun et al. | 2021
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Kinetics and mechanistic models of solid-liquid extraction of pectin using advance green techniques- a reviewDas, Ipsita / Arora, Amit et al. | 2021
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Effect of granule size on the structure and digestibility of jackfruit seed starchDong, Shiting / Fang, Guihong / Luo, Zhigang / Gao, Qunyu et al. | 2021
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Linear and non-linear rheology of heat-set soy protein gels: Effects of selective proteolysis of β-conglycinin and glycininXia, Wenjie / Siu, Wing Kie / Sagis, Leonard M.C. et al. | 2021
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Fermentation outcomes of wheat cell wall related polysaccharides are driven by substrate effects as well as initial faecal inoculumLu, Shiyi / Williams, Barbara A. / Flanagan, Bernadine M. / Yao, Hong / Mikkelsen, Deirdre / Gidley, Michael J. et al. | 2021
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Development and characterization of whey protein isolate and xylan composite films with and without enzymatic crosslinkingSeiwert, Karl / Kamdem, Donatien-Pascal / Kocabaş, Didem Sutay / Ustunol, Zeynep et al. | 2021
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Determination of critical gel-sol transition point of Highly Concentrated Micellar Casein Concentrate using multiple waveform rheological techniqueZad Bagher Seighalani, Fariba / McMahon, Donald J. / Sharma, Prateek et al. | 2021
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Structural characteristics of gluconic acid δ-lactone induced casein gels as regulated by gellan gum incorporationLi, Xiaofei / Guo, Chuo / Li, Peiyuan / Sun, Jiaojiao / Yang, Xi / Guo, Yurong et al. | 2021
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Meat analog production through artificial muscle fiber insertion using coaxial nozzle-assisted three-dimensional food printingKo, Hyun Jung / Wen, Yaxin / Choi, Ji Ho / Park, Bo Ram / Kim, Hyun Woo / Park, Hyun Jin et al. | 2021
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In vitro digestibility of gels from different starches: Relationship between kinetic parameters and microstructureAleixandre, Andrea / Benavent-Gil, Yaiza / Moreira, R. / Rosell, Cristina M. et al. | 2021
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Secalin enzymatically cross-linked by either papain and N-acetyl-dl-homocysteine thiolactone or transglutaminase: Improving of protein functional properties and film manufacturingQazanfarzadeh, Zeinab / Kadivar, Mahdi / Shekarchizadeh, Hajar / Di Girolamo, Rocco / Giosafatto, C. Valeria L. / Porta, Raffaele et al. | 2021
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Mechanistic studies of starch retrogradation and its effects on starch gel propertiesLiu, Xia / Chao, Chen / Yu, Jinglin / Copeland, Les / Wang, Shujun et al. | 2021
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Characterization of chitosan-hydroxypropyl methylcellulose blend films enriched with nettle or sage leaf extract for active food packaging applicationsBigi, Francesco / Haghighi, Hossein / Siesler, Heinz Wilhelm / Licciardello, Fabio / Pulvirenti, Andrea et al. | 2021
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Editorial Board| 2021
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Microwave irradiation alters the rheological properties and molecular structure of hull-less barley starchChen, Xiaojing / Liu, Yi / Xu, Zekun / Zhang, Chuangchuang / Liu, Xingxun / Sui, Zhongquan / Corke, Harold et al. | 2021
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Fabrication of thermally and mechanically stable superhydrophobic coatings for cellulose-based substrates with natural and edible ingredients for food applicationsWang, Taoran / Zhao, Yanyun et al. | 2021
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Formulation and additive manufacturing of polysaccharide-surfactant hybrid gels as gelatin analogues in food applicationsFenton, Thomas / Gholamipour-Shirazi, Azarmidokht / Daffner, Kilian / Mills, Tom / Pelan, Eddie et al. | 2021
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Synergistic effect of glycyrrhizic acid and cellulose nanocrystals for oil-water interfacial stabilizationMa, Lulu / Bertsch, Pascal / Wan, Zhili / Yang, Xiaoquan / Fischer, Peter et al. | 2021
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Konjac glucomannan molecular and rheological properties that delay gastric emptying and improve the regulation of appetiteGuo, Liping / Yokoyama, Wallace / Chen, Maoshen / Zhong, Fang et al. | 2021
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Physicochemical, rheological and digestibility characterization of starch extracted from the marine green macroalga Ulva ohnoiKazir, Meital / Gurevich, Daniel / Groobman, Ari / Prabhu, Meghanath / Israel, Álvaro / Golberg, Alexander / Livney, Yoav D. et al. | 2021
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Influence of cyclodextrins on the gelation behavior of κ-carrageenan/konjac glucomannan composite gelYuan, Chao / Zou, Yiyuan / Cui, Bo / Fang, Yishan / Lu, Lu / Xu, Dongyan et al. | 2021
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Printability, stability and sensory properties of protein-enriched 3D-printed lemon mousse for personalised in-between mealsChow, Ching Yue / Thybo, Camilla Doris / Sager, Valeska Farah / Riantiningtyas, Reisya Rizki / Bredie, Wender L.P. / Ahrné, Lilia et al. | 2021
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Effect of surface charge density of bacterial cellulose nanofibrils on the rheology property of O/W Pickering emulsionsWu, Yilan / Zhang, Xingzhong / Qiu, Dan / Pei, Ying / Li, Yan / Li, Bin / Liu, Shilin et al. | 2021
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Synergistic effect of hemiacetal crosslinking and crystallinity on wet strength of cellulose nanofiber-reinforced starch filmsSoni, Raghav / Hsu, Yu-I / Asoh, Taka-Aki / Uyama, Hiroshi et al. | 2021
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Effects of ultrasound, freeze-thaw pretreatments and drying methods on structure and functional properties of pectin during the processing of okraXu, Xin / Zhang, Lei / Yagoub, Abu ElGasim A. / Yu, Xiaojie / Ma, Haile / Zhou, Cunshan et al. | 2021
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Water-resistant nanopaper with tunable water barrier and mechanical properties from assembled complexes of oppositely charged cellulosic nanomaterialsZhang, Kaitao / Ismail, Mostafa Y. / Liimatainen, Henrikki et al. | 2021
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Macroalgae suspensions prepared by physical treatments: Effect of polysaccharide composition and microstructure on the rheological propertiesMalafronte, Loredana / Yilmaz-Turan, Secil / Krona, Annika / Martinez-Sanz, Marta / Vilaplana, Francisco / Lopez-Sanchez, Patricia et al. | 2021
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Controlled release of antioxidants from active food packaging: A reviewKuai, Lingyun / Liu, Fei / Chiou, Bor-Sen / Avena-Bustillos, Roberto J. / McHugh, Tara H. / Zhong, Fang et al. | 2021
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Graphical abstract TOC| 2021
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Characterization and physicochemical properties analysis of konjac glucomannan: Implications for structure-properties relationshipsGuo, Liping / Yokoyama, Wallace / Chen, Ling / Liu, Fei / Chen, Maoshen / Zhong, Fang et al. | 2021
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Co-stabilization and properties regulation of Pickering emulsions by cellulose nanocrystals and nanofibrils from lemon seedsDai, Hongjie / Zhang, Huan / Chen, Yuan / Ma, Liang / Wu, Jihong / Zhang, Yuhao et al. | 2021
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Structural, functional, and chemical properties of small starch granules: Andean quinoa and kiwichaVelásquez-Barreto, Frank F. / Miñano, Hubert Arteaga / Alvarez-Ramirez, Jose / Bello-Pérez, Luis.A. et al. | 2021
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Tribology and QCM-D approaches provide mechanistic insights into red wine mouthfeel, astringency sub-qualities and the role of salivaWang, Shaoyang / Olarte Mantilla, Sandra M. / Smith, Paul A. / Stokes, Jason R. / Smyth, Heather E. et al. | 2021
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Alginate-based emulsion micro-gel particles produced by an external/internal O/W/O emulsion-gelation method: Formation, suspension rheology, digestion, and application to gel-in-gel beadsLin, Duanquan / Kelly, Alan L. / Miao, Song et al. | 2021
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Low-frequency ultrasonication modulates the impact of annealing on physicochemical and functional properties of rice flourVela, Antonio J. / Villanueva, Marina / Ronda, Felicidad et al. | 2021
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Oligosaccharide-lactoferrin shell-crosslinked particles for selective targeting of proteins to probiotic bacteria in the colonPeled, Stav / Livney, Yoav D. et al. | 2021
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Pomelo pectin and fiber: Some perspectives and applications in food industryGamonpilas, C. / Buathongjan, C. / Kirdsawasd, T. / Rattanaprasert, M. / Klomtun, M. / Phonsatta, N. / Methacanon, P. et al. | 2021
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Microencapsulating polymers for probiotics delivery systems: Preparation, characterization, and applicationsRazavi, Seyedehhamideh / Janfaza, Sajjad / Tasnim, Nishat / Gibson, Deanna L. / Hoorfar, Mina et al. | 2021
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Release of fireweed extract (Epilobium angustifolium L.) from corn starch- and methylcellulose-based films - A comparative studyKowalczyk, Dariusz / Szymanowska, Urszula / Skrzypek, Tomasz / Bartkowiak, Artur / Materska, Małgorzata / Łupina, Katarzyna et al. | 2021
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Reduction of saturated fat in chocolate by using sunflower oil-hydroxypropyl methylcellulose based oleogelsEspert, M. / Hernández, M.J. / Sanz, T. / Salvador, A. et al. | 2021
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Whey protein isolate modified with sodium tripolyphosphate gel: A novel pH-sensitive system for controlled release of Lactobacillus plantarumZhang, An-Qi / He, Jia-Ling / Wang, Yan / Zhang, Xu / Piao, Zan-Hao / Xue, Yu-Ting / Zhang, Ying-Hua et al. | 2021
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Heat mediated physicochemical and structural changes of wheat gluten in the presence of salt and alkaliHan, Chuanwu / Ma, Meng / Yang, Tianbao / Li, Man / Sun, Qingjie et al. | 2021
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Development of a simulated tongue substrate for in vitro soft “oral” tribology studyWang, Qi / Zhu, Yang / Chen, Jianshe et al. | 2021
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Adsorption kinetics and dilatational rheological properties of recombinant Pea Albumin-2 at the oil-water interfaceLuo, Yilun / Zheng, Wei / Shen, Qian / Zhang, Li / Tang, Cuie / Song, Rong / Liu, Shilin / Li, Bin / Chen, Yijie et al. | 2021
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How pea fractions with different protein composition and purity can substitute WPI in heat-set gelsKornet, Remco / Penris, Simone / Venema, Paul / van der Goot, Atze Jan / Meinders, Marcel B.J. / van der Linden, Erik et al. | 2021
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Investigation of enzyme-assisted methods combined with ultrasonication under a controlled alkali pretreatment for agar extraction from Gelidium sesquipedaleLi, Yuchen / Zhao, Ming / Gomez, Laura P. / Senthamaraikannan, Ramsankar / Padamati, Ramesh Babu / O'Donnell, Colm P. / Tiwari, Brijesh K. et al. | 2021
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A new method to isolate and separate small and large starch granules from barley and maltDe Schepper, C.F. / Gielens, D.R.S. / Courtin, C.M. et al. | 2021
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Explore the interaction mechanism between zein and EGCG using multi-spectroscopy and molecular dynamics simulation methodsLiu, Chengzhi / Lv, Nan / Ren, Gerui / Wu, Ruibo / Wang, Binju / Cao, Zexing / Xie, Hujun et al. | 2021
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Quinoa protein-gum Arabic complex coacervates as a novel carrier for eugenol: Preparation, characterization and application for minced pork preservationChen, Kai / Zhang, Min / Mujumdar, Arun S. / Wang, Haixiang et al. | 2021
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Recent progress in understanding fundamental interactions and applications of zeinGiteru, Stephen Gitonga / Ali, M. Azam / Oey, Indrawati et al. | 2021
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The role of arabinoxylan in determining the non-linear and linear rheology of bread doughs made from blends of wheat (Triticum aestivum L.) and rye (Secale cereale L.) flourMeeus, Yannick / Janssen, Frederik / Wouters, Arno G.B. / Delcour, Jan A. / Moldenaers, Paula et al. | 2021
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Self-assembled soy protein nanoparticles by partial enzymatic hydrolysis for pH-Driven Encapsulation and Delivery of Hydrophobic Cargo CurcuminYuan, Dan / Zhou, Feibai / Shen, Penghui / Zhang, Yuanhong / Lin, Lianzhu / Zhao, Mouming et al. | 2021
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Rheological properties of quinoa-based gels. An alternative for vegan dietsFelix, Manuel / Camacho-Ocaña, Zulema / López-Castejón, M. Luisa / Ruiz-Domínguez, Manuela et al. | 2021
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The effect of heat moisture treatment on crystallinity and physicochemical-digestibility properties of purple yam flourAsranudin / Holilah / Syarifin, Andi Noor Kholidha / Purnomo, Adi Setyo / Ansharullah / Fudholi, Ahmad et al. | 2021
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Sequential maltogenic α-amylase and branching enzyme treatment to modify granular corn starchZhong, Yuyue / Herburger, Klaus / Kirkensgaard, Jacob Judas Kain / Khakimov, Bekzod / Hansen, Aleksander Riise / Blennow, Andreas et al. | 2021
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Structure and rheology of foams stabilized by lupin protein isolate of Lupinus.angustifoliusVölp, Annika R. / Seitz, Jonas / Willenbacher, Norbert et al. | 2021
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In vitro fecal fermentation outcomes of starch-lipid complexes depend on starch assembles more than lipid typeZhou, Qianwen / Fu, Xiong / Dhital, Sushil / Zhai, Honglei / Huang, Qiang / Zhang, Bin et al. | 2021
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Corrigendum to “Protein particles ameliorate the mechanical properties of highly polyunsaturated oil-based whipped cream: A possible mode of action” [Food Hydrocolloids 99 (2020) 105350]Cao, Zhenyu / Liu, Zelong / Zhang, Huijuan / Wang, Jing / Ren, Shuncheng et al. | 2020
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Encapsulation of Lactobacillus casei in quince seed gum-alginate beads to produce a functional synbiotic drink powder by agro-industrial by-products and freeze-dryingJouki, Mohammad / Khazaei, Naimeh / Rashidi-Alavijeh, Somayeh / Ahmadi, Sara et al. | 2021
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Physical modification of Lepidium perfoliatum seed gum using cold atmospheric-pressure plasma treatmentSadeghi, Fatemeh / Koocheki, Arash / Shahidi, Fakhri et al. | 2021
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Rheological characterization of a physically-modified waxy potato starch: Investigation of its shear-thickening mechanismAng, Cai Ling / Tha Goh, Kelvin Kim / Lim, Kaiyang / Matia-Merino, Lara et al. | 2021
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The underlying mechanism of alkali-induced ovalbumin gel transforms to sol: Physicochemical properties, structure and quantitative protein degradation analysisGao, Xuejing / Yao, Yao / Wu, Na / Xu, Mingsheng / Zhao, Yan / Tu, Yonggang et al. | 2021
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Synthesis, physicochemical and emulsifying properties of C-3 octenyl succinic anhydride-modified corn starchGao, Wei / Liu, Pengfei / Wang, Bin / Kang, Xuemin / Zhu, Jie / Cui, Bo / Abd El-Aty, A.M. et al. | 2021
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Development of novel biopolymer-based dendritic nanocomplexes for encapsulation of phenolic bioactive compounds: A proof-of-concept studyXue, Jingyi / Luo, Yaguang / Balasubramanian, Brindhalakshmi / Upadhyay, Abhinav / Li, Zhenshun / Luo, Yangchao et al. | 2021
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Pectin degradation accounts for apple tissue fragmentation during thermomechanical-mediated puree productionBuergy, Alexandra / Rolland-Sabaté, Agnès / Leca, Alexandre / Falourd, Xavier / Foucat, Loïc / Renard, Catherine M.G.C. et al. | 2021
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Exploring the relationships between oral sensory physiology and oral processing with mid infrared spectra of salivaNi, Dongdong / Smyth, Heather E. / Gidley, Michael J. / Cozzolino, Daniel et al. | 2021
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Development of starch texture rheological maps through empirical modeling of starch swelling behaviorJoyner, Helen S. / Wicklund, Rachel A. / Templeton, Catherine M. / Howarth, Leslie G. / Wong, Shen-Siung / Anvari, Mohammad / Whaley, Judith K. et al. | 2021
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Migration of red grape extract components and glycerol from soybean protein concentrate active films into food simulantsAgustinelli, Silvina P. / Ciannamea, Emiliano M. / Ruseckaite, Roxana A. / Martucci, Josefa F. et al. | 2021
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Thermodynamic parameters of gelatin-pectin complex coacervationXiong, Wenfei / Li, Ya / Ren, Cong / Li, Jing / Li, Bin / Geng, Fang et al. | 2021
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Construction of 3D printed reduced-fat meat analogue by emulsion gels. Part I: Flow behavior, thixotropic feature, and network structure of soy protein-based inksShahbazi, Mahdiyar / Jäger, Henry / Ettelaie, Rammile / Chen, Jianshe et al. | 2021
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Essential contributions of food hydrocolloids and phospholipid liposomes to the formation of carriers for controlled delivery of biologically active substances via the gastrointestinal tractSemenova, Maria / Antipova, Anna / Martirosova, Elena / Zelikina, Darya / Palmina, Nadezhda / Chebotarev, Sergey et al. | 2021
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Development of pH-responsive antioxidant soy protein isolate films incorporated with cellulose nanocrystals and curcumin nanocapsules to monitor shrimp freshnessXiao, Yaqing / Liu, Yingnan / Kang, Shufang / Cui, Mengdi / Xu, Huaide et al. | 2021
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Implementation of a novel continuous solid/liquid mixing accessory for 3D printing of dysphagia-oriented thickened fluidsDiañez, I. / Gallegos, C. / Brito-de la Fuente, E. / Martínez, I. / Valencia, C. / Sánchez, M.C. / Franco, J.M. et al. | 2021
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The role of dietary proteins and carbohydrates in gut microbiome composition and activity: A reviewPeled, Stav / Livney, Yoav D. et al. | 2021
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Sodium caseinate reduces the swelling of konjac flour: A further examinationLi, Shanshan / Shang, Longchen / Wu, Di / Dun, Huiyu / Wei, Xianling / Zhu, Jingsong / Zongo, Abel W.S. / Li, Bin / Geng, Fang et al. | 2021
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Interplay of interactions between micelles and fibrils of casein proteinsPortnaya, Irina / Khalfin, Rafail / Danino, Dganit et al. | 2021
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Interfacial adsorption behavior of ovalbumin/ sodium carboxymethyl cellulose colloidal particles: The effects of preparation methodsNiu, Fuge / Zhang, Qiuping / Yu, Jiao / Huo, Yucui / Zhuo, Lingchang / Niu, Debao / Pan, Weichun et al. | 2021
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Effect of sucrose substitution with stevia and saccharin on rheological properties of gels from sunflower pectinsMuñoz-Almagro, Nerea / Villamiel, Mar / Wilde, Peter J. / Gunning, A. Patrick / Montilla, Antonia et al. | 2021
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A review on colloidal delivery vehicles using carvacrol as a model bioactive compoundWang, Pu / Wu, Ying et al. | 2021
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Molecular structures of octenyl succinic anhydride modified starches in relation to their ability to stabilize high internal phase emulsions and oleogelsLiu, Xiao / Ding, Suwei / Wu, Jihong / Liu, Guodong / Wei, Jiaojiao / Yang, Fan / Liu, Xingxun et al. | 2021
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Understanding the different emulsification mechanisms of pectin: Comparison between watermelon rind and two commercial pectin sourcesMendez, D.A. / Fabra, M.J. / Martínez-Abad, A. / Μartínez-Sanz, Μ. / Gorria, M. / López-Rubio, A. et al. | 2021
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Evaluation of starch retrogradation by infrared spectroscopyLu, Hao / Ma, Rongrong / Chang, Ranran / Tian, Yaoqi et al. | 2021
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Application of starch nanoparticles as a stabilizer for Pickering emulsions: Effect of environmental factors and approach for enhancing its storage stabilityKo, Eun Byul / Kim, Jong-Yea et al. | 2021
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Preparation of crocin nanocomplex in order to increase its physical stabilityLi, Dongze / Wu, Gangcheng / Zhang, Hui / Qi, Xiguang et al. | 2020
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The rheological properties of bovine β-Lactoglobulin stabilized oil/water interfaces depend on the protein's quaternary structureRamamirtham, Sashikumar / Whitby, Catherine P. / Zare, Davoud / Weeks, Mike / Williams, Martin A.K. et al. | 2021
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Polysaccharide-stabilized aqueous foams to fabricate highly oil-absorbing cryogels: Application and formation process for preparation of edible oleogelsJiang, Qinbo / Du, Liyang / Li, Shaoyang / Liu, Yuanfa / Meng, Zong et al. | 2021
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Effects of different hydrocolloids on gelatinization and gels structure of chestnut starchLiu, Wenmeng / Wang, Rongrong / Li, Jinwang / Xiao, Wenhao / Rong, Liyuan / Yang, Jun / Wen, Huiliang / Xie, Jianhua et al. | 2021
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Impact of ethanol addition on the behaviour of xanthan gum in aqueous mediaBrunchi, Cristina-Eliza / Morariu, Simona / Bercea, Maria et al. | 2021
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Utilization of maltogenic α-amylase treatment to enhance the functional properties and reduce the digestibility of pulse starchesLi, Jiayi / Li, Liying / Zhu, Jianfeng / Ai, Yongfeng et al. | 2021
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A novel underutilized starch resource— Lucuma nervosa A.DC seed and fruitLi, Bo / Zhang, Yutong / Zhang, Yayuan / Zhang, Yanjun / Xu, Fei / Zhu, Kexue / Huang, Chongxing et al. | 2021
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Physicochemical properties and bioavailability comparison of two quercetin loading zein nanoparticles with outer shell of caseinate and chitosanZhou, Jian-Feng / Zheng, Guo-Dong / Wang, Wen-Jun / Yin, Zhong-Ping / Chen, Ji-Guang / Li, Jing-En / Zhang, Qing-Feng et al. | 2021
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Encapsulation of quercetin in biopolymer-coated zein nanoparticles: Formation, stability, antioxidant capacity, and bioaccessibilityZou, Yan / Qian, Yi / Rong, Xiaoyun / Cao, Kaixin / McClements, David Julian / Hu, Kun et al. | 2021