1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2 (English)
- New search for: Nickell, Justin R.
- New search for: Culver, John P.
- New search for: Janganati, Venumadhav
- New search for: Zheng, Guangrong
- New search for: Dwoskin, Linda P.
- New search for: Crooks, Peter A.
- Further information on Crooks, Peter A.:
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https://orcid.org/0000-0002-1312-6150
- New search for: Nickell, Justin R.
- New search for: Culver, John P.
- New search for: Janganati, Venumadhav
- New search for: Zheng, Guangrong
- New search for: Dwoskin, Linda P.
- New search for: Crooks, Peter A.
In:
Bioorganic and Medicinal Chemistry Letters
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26
, 13
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2997-3000
;
2016
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ISSN:
- Article (Journal) / Electronic Resource
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Title:1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2
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Contributors:Nickell, Justin R. ( author ) / Culver, John P. ( author ) / Janganati, Venumadhav ( author ) / Zheng, Guangrong ( author ) / Dwoskin, Linda P. ( author ) / Crooks, Peter A. ( author )
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Published in:Bioorganic and Medicinal Chemistry Letters ; 26, 13 ; 2997-3000
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Publisher:
- New search for: Elsevier Ltd
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Publication date:2016-05-09
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Size:4 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 26, Issue 13
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2975
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Solubility-driven lead optimisation: Recent examples and personal perspectivesAhmad, Nadia M. et al. | 2016
- 2980
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Caged xanthones: Potent inhibitors of global predominant MRSA USA300Chaiyakunvat, Pongkorn / Anantachoke, Natthinee / Reutrakul, Vichai / Jiarpinitnun, Chutima et al. | 2016
- 2984
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Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Gogliotti, Rocco D. / Blobaum, Anna L. / Morrison, Ryan M. / Daniels, J. Scott / Salovich, James M. / Cheung, Yiu-Yin / Rodriguez, Alice L. / Loch, Matthew T. / Conn, P. Jeffrey / Lindsley, Craig W. et al. | 2016
- 2988
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Synthesis and decreasing Aβ content evaluation of arctigenin-4-yl carbamate derivativesXu, Xingyu / Li, Cong / Lei, Min / Zhu, Zhiyuan / Yan, Jianming / Shen, Xu / Hu, Lihong et al. | 2016
- 2992
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Effect of carbon chain length in acyl coenzyme A on the efficiency of enzymatic transformation of okadaic acid to 7-O-acyl okadaic acidFurumochi, Sachie / Onoda, Tatsuya / Cho, Yuko / Fuwa, Haruhiko / Sasaki, Makoto / Yotsu-Yamashita, Mari / Konoki, Keiichi et al. | 2016
- 2997
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1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2Nickell, Justin R. / Culver, John P. / Janganati, Venumadhav / Zheng, Guangrong / Dwoskin, Linda P. / Crooks, Peter A. et al. | 2016
- 3001
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Synthesis and biological activity of pyrrole analogues of combretastatin A-4Jung, Eun-Kyung / Leung, Euphemia / Barker, David et al. | 2016
- 3006
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Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activitiesBeteck, Richard M. / Coertzen, Dina / Smit, Frans J. / Birkholtz, Lyn-Marie / Haynes, Richard K. / N’Da, David D. et al. | 2016
- 3010
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Conformational analysis of 2-substituted piperazinesKallel, E. Adam / Vangel, Colin / Elbaum, Daniel et al. | 2016
- 3014
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Quinazolinones–Phenylquinoxaline hybrids with unsaturation/saturation linkers as novel anti-proliferative agentsPalem, Jyothsna Devi / Alugubelli, Gopi Reddy / Bantu, Rajashaker / Nagarapu, Lingaiah / Polepalli, Sowjanya / Jain, S. Nishanth / Bathini, Raju / Manga, Vijjulatha et al. | 2016
- 3019
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Enantioselective syntheses of both enantiomers of 9′-dehydroxyimperanene and 7,8-dihydro-9′-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acidsYamauchi, Satoshi / Tanimura, Ryosuke / Nishiwaki, Hisashi / Nishi, Kosuke / Sugahara, Takuya / Maruyama, Masafumi / Ano, Yoshitaka / Akiyama, Koichi / Kishida, Taro et al. | 2016
- 3024
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Synthesis and biological evaluation of oxindole linked indolyl-pyrimidine derivatives as potential cytotoxic agentsPrajapti, Santosh Kumar / Nagarsenkar, Atulya / Guggilapu, Sravanthi Devi / Gupta, Keshav Kumar / Allakonda, Lingesh / Jeengar, Manish Kumar / Naidu, V.G.M. / Babu, Bathini Nagendra et al. | 2016
- 3029
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Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine coreWood, Michael R. / Noetzel, Meredith J. / Engers, Julie L. / Bollinger, Katrina A. / Melancon, Bruce J. / Tarr, James C. / Han, Changho / West, Mary / Gregro, Alison R. / Lamsal, Atin et al. | 2016
- 3034
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Synthesis of chlorophyll-a derivatives methylated in the 3-vinyl group and their intrinsic site energyTamiaki, Hitoshi / Tsuji, Kazuki / Kuno, Masaki / Kimura, Yuki / Watanabe, Hiroaki / Miyatake, Tomohiro et al. | 2016
- 3038
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Discovery of (S)-4-isobutyloxazolidin-2-one as a novel leucyl-tRNA synthetase (LRS)-targeted mTORC1 inhibitorYoon, Suyoung / Kim, Jong Hyun / Yoon, Ina / Kim, Changhoon / Kim, Sung-Eun / Koh, Yura / Jeong, Seung Jae / Lee, Jiyoun / Kim, Sunghoon / Lee, Jeewoo et al. | 2016
- 3042
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Synthesis, antitumor evaluation and molecular docking studies of [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivativesXu, Feng / Yang, Zhen-zhen / Jiang, Jun-rong / Pan, Wan-gui / Yang, Xiao-le / Wu, Jian-yong / Zhu, Yan / Wang, John / Shou, Qi-Yang / Wu, Han-gui et al. | 2016
- 3048
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Synthesis and evaluation of novel benzylphthalazine derivatives as hedgehog signaling pathway inhibitorsBao, Xiaolong / Peng, Yuanqiu / Lu, Xiuhong / Yang, Jun / Zhao, Weili / Tan, Wenfu / Dong, Xiaochun et al. | 2016
- 3052
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Structure-based discovery of novel 4,5,6-trisubstituted pyrimidines as potent covalent Bruton’s tyrosine kinase inhibitorsZou, Yi / Xiao, Jianhu / Tu, Zhengchao / Zhang, Yingyi / Yao, Kun / Luo, Minghao / Ding, Ke / Zhang, Yihua / Lai, Yisheng et al. | 2016
- 3060
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New anti-inflammatory sterols from a gorgonian Pinnigorgia sp.Su, Yin-Di / Cheng, Ching-Hsiao / Wen, Zhi-Hong / Wu, Yang-Chang / Sung, Ping-Jyun et al. | 2016
- 3064
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Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1,3-benzoazole derivatives bearing amide unitsLi, Jiling / Wu, Dang / Xu, Xiaoyong / huang, Jin / Shao, Xusheng / Li, Zhong et al. | 2016
- 3067
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Design and synthesis of novel benzoxazole analogs as Aurora B kinase inhibitorsAn, Ying / Lee, Eun / Yu, Yeongji / Yun, Jieun / Lee, Myeong Youl / Kang, Jong Soon / Kim, Woo-Young / Jeon, Raok et al. | 2016
- 3073
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Discovery of novel 7-azaindoles as PDK1 inhibitorsWucherer-Plietker, Margarita / Merkul, Eugen / Müller, Thomas J.J. / Esdar, Christina / Knöchel, Thorsten / Heinrich, Timo / Buchstaller, Hans-Peter / Greiner, Hartmut / Dorsch, Dieter / Finsinger, Dirk et al. | 2016
- 3081
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Steroids from the rhizome of Anemarrhena asphodeloides and their cytotoxic activitiesSun, Yu / Wu, Jie / Sun, Xue / Huang, Xiaoxiao / Li, Lingzhi / Liu, Qingbo / Song, ShaoJiang et al. | 2016
- 3086
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Identification, library synthesis and anti-vibriosis activity of 2-benzyl-4-chlorophenol from cultures of the marine bacterium Shewanella halifaxensisMoore, Sarah L. / Berthomier, Lucile / Braganza, Chriselle D. / MacKichan, Joanna K. / Ryan, Jason L. / Visnovsky, Gabriel / Keyzers, Robert A. et al. | 2016
- 3089
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Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agentsZhang, Xing / Khalidi, Omar / Kim, So Young / Wang, Ruitong / Schultz, Victor / Cress, Brady F. / Gross, Richard A. / Koffas, Mattheos A.G. / Linhardt, Robert J. et al. | 2016
- 3093
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Design, synthesis, structure–activity relationship and kinase inhibitory activity of substituted 3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-onesLamie, Phoebe F. et al. | 2016
- 3098
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The synthesis and synergistic antifungal effects of chalcones against drug resistant Candida albicansWang, Yuan-Hua / Dong, Huai-Huai / Zhao, Fei / Wang, Jie / Yan, Fang / Jiang, Yuan-Ying / Jin, Yong-Sheng et al. | 2016
- 3103
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Design and synthesis of novel hydroxypyridinone derivatives as potential tyrosinase inhibitorsZhao, De-Yin / Zhang, Ming-Xia / Dong, Xiao-Wu / Hu, Yong-Zhou / Dai, Xiao-Yan / Wei, Xiaoyi / Hider, Robert C. / Zhang, Jin-Chao / Zhou, Tao et al. | 2016
- 3109
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The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitorsKeith, John M. / Tichenor, Mark S. / Apodaca, Richard L. / Xiao, Wei / Jones, William M. / Seierstad, Mark / Pierce, Joan M. / Palmer, James A. / Webb, Michael / Karbarz, Mark J. et al. | 2016
- 3115
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Photoinduced apoptosis using a peptide carrying a photosensitizerWatanabe, Kazunori / Fujiwara, Hayato / Kitamatsu, Mizuki / Ohtsuki, Takashi et al. | 2016
- 3119
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Enantioselective synthesis and antioxidant activity of 3,4,5-substituted piperidine derivativesKim, Jin Ho / Shyam, Pranab K. / Kim, Mi Jeong / Lee, Hwa-Jung / Lee, Jeong Tae / Jang, Hye-Young et al. | 2016
- 3122
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Synergistic potentiation of (−)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821Colis, Laureen C. / Herzon, Seth B. et al. | 2016
- 3127
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GroEL/ES inhibitors as potential antibioticsAbdeen, Sanofar / Salim, Nilshad / Mammadova, Najiba / Summers, Corey M. / Frankson, Rochelle / Ambrose, Andrew J. / Anderson, Gregory G. / Schultz, Peter G. / Horwich, Arthur L. / Chapman, Eli et al. | 2016
- 3135
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Synthesis and antitubercular evaluation of novel dibenzo[b,d]thiophene tethered imidazo[1,2-a]pyridine-3-carboxamidesPulipati, Lokesh / Sridevi, Jonnalagadda Padma / Yogeeswari, Perumal / Sriram, Dharmarajan / Kantevari, Srinivas et al. | 2016
- 3141
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Synthesis, structure–activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychoticsYang, Feipu / Jiang, Xiangrui / Li, Jianfeng / Wang, Yu / Liu, Yongjian / Bi, Minghao / Wu, Chunhui / Zhao, Qingjie / Chen, Weiming / Yin, Jingjing et al. | 2016
- 3148
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Identification of novel aminopiperidine derivatives for antibacterial activity against Gram-positive bacteriaLee, Hee-Yeol / An, Kyung-Mi / Jung, Juyoung / Koo, Je-Min / Kim, Jeong-Geun / Yoon, Jong-Min / Lee, Myong-Jae / Jang, HyeonSoo / Lee, Hong-Sub / Park, Soobong et al. | 2016
- 3153
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Interpreting the behavior of concentration–response curves of hyaluronidase inhibitors under DMSO-perturbed assay conditionsTomohara, Keisuke / Ito, Tomohiro / Onikata, Saika / Furusawa, Kota / Kato, Atsushi / Adachi, Isao et al. | 2016
- 3158
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Discovery of fused tricyclic core containing HCV NS5A inhibitors with pan-genotype activityYu, Wensheng / Coburn, Craig A. / Yang, De-Yi / Meinke, Peter T. / Wong, Michael / Rosenblum, Stuart B. / Chen, Kevin X. / Njoroge, George F. / Chen, Lei / Dwyer, Michael P. et al. | 2016
- 3163
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Natural nitric oxide (NO) inhibitors from Chloranthus japonicusGuo, Yan-Qiong / Zhao, Jing-Jun / Li, Zhen-Zhen / Tang, Gui-Hua / Zhao, Zhi-Min / Yin, Sheng et al. | 2016
- 3167
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Sequential one-pot synthesis of bis(indolyl)glyoxylamides: Evaluation of antibacterial and anticancer activitiesTantak, Mukund P. / Gupta, Vishakha / Nikhil, Kumar / Arun, V. / Singh, Rajnish Prakash / Jha, Prabhat Nath / Shah, Kavita / Kumar, Dalip et al. | 2016
- 3172
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Synthesis and anti-proliferative activity of fluoro-substituted chalconesBurmaoglu, Serdar / Algul, Oztekin / Anıl, Derya Aktas / Gobek, Arzu / Duran, Gulay Gulbol / Ersan, Ronak Haj / Duran, Nizami et al. | 2016
- 3177
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One step N-glycosylation by filamentous fungi biofilm in bioreactor of a new phosphodiesterase-3 inhibitor tetrazolede Melo Souza, Paula L. / Arruda, Evilanna L. / Pazini, Francine / Menegatti, Ricardo / Vaz, Boniek G. / Lião, Luciano M. / de Oliveira, Valéria et al. | 2016
- 3182
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Optimization of isoxazoline amide benzoxaboroles for identification of a development candidate as an oral long acting animal ectoparasiticideZhang, Yong-Kang / Plattner, Jacob J. / Easom, Eric E. / Akama, Tsutomu / Zhou, Yasheen / White, W. Hunter / Defauw, Jean M. / Winkle, Joseph R. / Balko, Terry W. / Cao, Jianxin et al. | 2016
- 3187
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Identification of quinones as novel PIM1 kinase inhibitorsSchroeder, Richard L. / Goyal, Navneet / Bratton, Melyssa / Townley, Ian / Pham, Nancy A. / Tram, Phan / Stone, Treasure / Geathers, Jasmine / Nguyen, Kathy / Sridhar, Jayalakshmi et al. | 2016
- 3192
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Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitorsDi Matteo, Mauro / Ammazzalorso, Alessandra / Andreoli, Federico / Caffa, Irene / De Filippis, Barbara / Fantacuzzi, Marialuigia / Giampietro, Letizia / Maccallini, Cristina / Nencioni, Alessio / Parenti, Marco Daniele et al. | 2016
- 3195
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Protective effect of novel substituted nicotine hydrazide analogues against hypoxic brain injury in neonatal rats via inhibition of caspaseDeng, Chang-bo / Li, Juan / Li, Lu-yi / Sun, Feng-jie et al. | 2016
- 3202
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Discovery of triazolopyridine GS-458967, a late sodium current inhibitor (Late INai) of the cardiac NaV 1.5 channel with improved efficacy and potency relative to ranolazineKoltun, Dmitry O. / Parkhill, Eric Q. / Elzein, Elfatih / Kobayashi, Tetsuya / Notte, Gregory T. / Kalla, Rao / Jiang, Robert H. / Li, Xiaofen / Perry, Thao D. / Avila, Belem et al. | 2016
- 3207
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Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazineKoltun, Dmitry O. / Parkhill, Eric Q. / Elzein, Elfatih / Kobayashi, Tetsuya / Jiang, Robert H. / Li, Xiaofen / Perry, Thao D. / Avila, Belem / Wang, Wei-Qun / Hirakawa, Ryoko et al. | 2016
- IFC
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Editorial board| 2016