Synthesis, biological evaluation of 5-carbomethoxymethyl-7-hydroxy-2-pentylchromone, 5-carboethoxymethyl-4′,7-dihydroxyflavone and their analogues (English)
- New search for: Kamal, Ahmed
- New search for: Murty, J.N.S.R.C.
- New search for: Viswanath, A.
- New search for: Sujitha, P.
- New search for: Ganesh Kumar, C.
- New search for: Kamal, Ahmed
- New search for: Murty, J.N.S.R.C.
- New search for: Viswanath, A.
- New search for: Sujitha, P.
- New search for: Ganesh Kumar, C.
In:
Bioorganic and Medicinal Chemistry Letters
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22
, 14
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4891-4895
;
2012
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Synthesis, biological evaluation of 5-carbomethoxymethyl-7-hydroxy-2-pentylchromone, 5-carboethoxymethyl-4′,7-dihydroxyflavone and their analogues
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Contributors:Kamal, Ahmed ( author ) / Murty, J.N.S.R.C. ( author ) / Viswanath, A. ( author ) / Sujitha, P. ( author ) / Ganesh Kumar, C. ( author )
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Published in:Bioorganic and Medicinal Chemistry Letters ; 22, 14 ; 4891-4895
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Publisher:
- New search for: Elsevier Ltd
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Publication date:2012-05-02
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Size:5 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 22, Issue 14
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 4475
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Graphical contents list| 2012
- 4497
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Synthesis and study of cyclic pronucleotides of 5-fluoro-2prime-deoxyuridineJain, H. V. / Kalman, T. I. et al. | 2012
- 4497
-
Synthesis and study of cyclic pronucleotides of 5-fluoro-2′-deoxyuridineJain, Harsh V. / Kalman, Thomas I. et al. | 2012
- 4502
-
Contribution of indazolinone tautomers to kinase activityVasudevan, Anil / Verzal, Mary K. / Villamil, Clara I. / Stewart, Kent D. / Abad-Zapatero, Cele / Oie, Tetsuro / Djuric, Stevan W. et al. | 2012
- 4506
-
Discovery of nitroheterocycles active against African trypanosomes. In vitro screening and preliminary SAR studiesArán, Vicente J. / Kaiser, Marcel / Dardonville, Christophe et al. | 2012
- 4517
-
New farnesyltransferase inhibitors in the phenothiazine seriesBelei, Dalila / Dumea, Carmen / Samson, Alexandrina / Farce, Amaury / Dubois, Joëlle / Bîcu, Elena / Ghinet, Alina et al. | 2012
- 4523
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Study on anti-proliferative effect of benzoxathiole derivatives through inactivation of NF-κB in human cancer cellsVenkateswararao, Eeda / Anh, Hoang Le Tuan / Sharma, Vinay K. / Lee, Ki-Cheul / Sharma, Niti / Kim, Youngsoo / Jung, Sang-Hun et al. | 2012
- 4523
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Study on anti-proliferative effect of benzoxathiole derivatives through inactivation of NF-kB in human cancer cellsVenkateswararao, E. / Anh, H. L. / Sharma, V. K. / Lee, K. C. / Sharma, N. / Kim, Y. / Jung, S. H. et al. | 2012
- 4528
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Exploration of diverse hinge-binding scaffolds for selective Aurora kinase inhibitorsJi, Zhiqin / Dai, Yujia / Abad-Zapatero, Cele / Albert, Daniel H. / Bouska, Jennifer J. / Glaser, Keith B. / Marcotte, Patrick A. / Soni, Nirupama B. / Magoc, Terry J. / Stewart, Kent D. et al. | 2012
- 4532
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Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: Development of a highly selective and more potent in vitro probeDelpire, Eric / Baranczak, Aleksandra / Waterson, Alex G. / Kim, Kwangho / Kett, Nathan / Morrison, Ryan D. / Scott Daniels, J. / David Weaver, C. / Lindsley, Craig W. et al. | 2012
- 4536
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Synthesis and structure–activity relationship of disubstituted benzamides as a novel class of antimalarial agentsMitachi, Katsuhiko / Salinas, Yandira G. / Connelly, Michele / Jensen, Nicholas / Ling, Taotao / Rivas, Fatima et al. | 2012
- 4540
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CCLab—a multi-objective genetic algorithm based combinatorial library design software and an application for histone deacetylase inhibitor designFang, Guanghua / Xue, Mengzhu / Su, Mingbo / Hu, Dingyu / Li, Yanlian / Xiong, Bing / Ma, Lanping / Meng, Tao / Chen, Yuelei / Li, Jingya et al. | 2012
- 4546
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Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammationEllard, Katie / Sunose, Mihiro / Bell, Kathryn / Ramsden, Nigel / Bergamini, Giovanna / Neubauer, Gitte et al. | 2012
- 4546
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Discovery of novel PI3Kg/d inhibitors as potential agents for inflammationEllard, K. / Sunose, M. / Bell, K. / Ramsden, N. / Bergamini, G. / Neubauer, G. et al. | 2012
- 4550
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Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptorsMangin, Floriane / Dilly, Sébastien / Joly, Benoît / Scuvée-Moreau, Jacqueline / Evans, Jon / Setola, Vincent / Roth, Bryan L. / Liégeois, Jean-François et al. | 2012
- 4555
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Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibioticsTran, Thanh-Dao / Do, Tuong-Ha / Tran, Ngoc-Chau / Ngo, Trieu-Du / Huynh, Thi-Ngoc-Phuong / Tran, Cat-Dong / Thai, Khac-Minh et al. | 2012
- 4561
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Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isopropylhexanamides as renin inhibitorsNakamura, Yuji / Sugita, Chie / Meguro, Masaki / Miyazaki, Shojiro / Tamaki, Kazuhiko / Takahashi, Mizuki / Nagai, Yoko / Nagayama, Takahiro / Kato, Mikio / Suemune, Hiroshi et al. | 2012
- 4567
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Synthesis and biodistribution studies of technetium-99m-labeled aminopeptidase N inhibitor conjugatesPathuri, Gopal / Hedrick, Andria F. / Disch, Bryan C. / Ihnat, Michael A. / Awasthi, Vibhudutta / Gali, Hariprasad et al. | 2012
- 4571
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Synthesis of nucleoside 5′-boranophosphorothioate derivatives using an H-boranophosphonate monoester as a precursorOka, Natsuhisa / Takayama, Yuji / Ando, Kaori / Wada, Takeshi et al. | 2012
- 4571
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Synthesis of nucleoside 5prime-boranophosphorothioate derivatives using an H-boranophosphonate monoester as a precursorOka, N. / Takayama, Y. / Ando, K. / Wada, T. et al. | 2012
- 4575
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Synthesis and antibacterial activity of desosamine-modified macrolide derivativesLeTourneau, Nicolas / Vimal, Pavan / Klepacki, Dorota / Mankin, Alexander / Melman, Artem et al. | 2012
- 4579
-
An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRa and kitDeng, X. / Zhou, W. / Weisberg, E. / Wang, J. / Zhang, J. / Sasaki, T. / Nelson, E. / Griffin, J. D. / Janne, P. A. / Gray, N. S. et al. | 2012
- 4579
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An amino-indazole scaffold with spectrum selective kinase inhibition of FLT3, PDGFRα and kitDeng, Xianming / Zhou, Wenjun / Weisberg, Ellen / Wang, Jinhua / Zhang, Jianming / Sasaki, Takaaki / Nelson, Erik / Griffin, James D. / Jänne, Pasi A. / Gray, Nathanael S. et al. | 2012
- 4585
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Assay and inhibition of diacylglycerol lipase activityJohnston, Meghan / Bhatt, Shachi R. / Sikka, Surina / Mercier, Richard W. / West, Jay M. / Makriyannis, Alexandros / Gatley, S. John / Duclos, Richard I. Jr. et al. | 2012
- 4593
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Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesteraseHartsel, Joshua A. / Wong, Dawn M. / Mutunga, James M. / Ma, Ming / Anderson, Troy D. / Wysinski, Ania / Islam, Rafique / Wong, Eric A. / Paulson, Sally L. / Li, Jianyong et al. | 2012
- 4599
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Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinasesDakin, Les A. / Block, Michael H. / Chen, Huawei / Code, Erin / Dowling, James E. / Feng, Xiaomei / Ferguson, Andrew D. / Green, Isabelle / Hird, Alexander W. / Howard, Tina et al. | 2012
- 4605
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Technetium-99m-labeled ceftizoxime loaded long-circulating and pH-sensitive liposomes used to identify osteomyelitisFerreira, Soraya Maria Zandim Maciel Dias / Domingos, Giselle Pires / Ferreira, Diego dos Santos / Rocha, Talita Guieiro Ribeiro / Serakides, Rogéria / de Faria Rezende, Cleuza Maria / Cardoso, Valbert Nascimento / Fernandes, Simone Odília Antunes / Oliveira, Mônica Cristina et al. | 2012
- 4609
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Small molecular weight PEGylation of diosgenin in an in vivo animal study for diabetic auditory impairment treatmentKim, Dong-Hwan / Hong, Bin Na / Le, Hoa Thi / Hong, Ha Na / Lim, Choon Woo / Park, Keun Ha / Kim, Tae Woo / Kang, Tong Ho et al. | 2012
- 4613
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Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory diseaseSunose, Mihiro / Bell, Kathryn / Ellard, Katie / Bergamini, Giovanna / Neubauer, Gitte / Werner, Thilo / Ramsden, Nigel et al. | 2012
- 4619
-
Discovery and modification of sulfur-containing heterocyclic pyrazoline derivatives as potential novel class of β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitorsYang, Yu-Shun / Zhang, Fei / Gao, Chao / Zhang, Yan-Bin / Wang, Xiao-Liang / Tang, Jian-Feng / Sun, Jian / Gong, Hai-Bin / Zhu, Hai-Liang et al. | 2012
- 4619
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Discovery and modification of sulfur-containing heterocyclic pyrazoline derivatives as potential novel class of b-ketoacyl-acyl carrier protein synthase III (FabH) inhibitorsYang, Y. S. / Zhang, F. / Gao, C. / Zhang, Y. B. / Wang, X. L. / Tang, J. F. / Sun, J. / Gong, H. B. / Zhu, H. L. et al. | 2012
- 4625
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Xanthine oxidase inhibitory activity of constituents of Cinnamomum cassia twigsNgoc, Tran Minh / Khoi, Nguyen Minh / Ha, Do Thi / Nhiem, Nguyen Xuan / Tai, Bui Huu / Don, Dao Van / Luong, Hoang Van / Son, Doan Cao / Bae, KiHwan et al. | 2012
- 4629
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Construction and functionalization of fused pyridine ring leading to novel compounds as potential antitubercular agentsDulla, Balakrishna / Wan, Baojie / Franzblau, Scott G. / Kapavarapu, Ravikumar / Reiser, Oliver / Iqbal, Javed / Pal, Manojit et al. | 2012
- 4636
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Synthesis of novel imbricatolic acid analogues via insertion of N-substituted piperazine at C-15/C-19 positions, displaying glucose uptake stimulation in L6 skeletal muscle cellsKhan, Mohammad Faheem / Kumar, Padam / Pandey, Jyotsana / Srivastava, Arvind Kumar / Tamrakar, Akhilesh Kumar / Maurya, Rakesh et al. | 2012
- 4640
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Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 positionHamada, Yoshio / Nakanishi, Tomoya / Suzuki, Kenji / Yamaguchi, Ryoji / Hamada, Takashi / Hidaka, Koushi / Ishiura, Shoichi / Kiso, Yoshiaki et al. | 2012
- 4645
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Structure-based optimization of aminopyridines as PKCθ inhibitorsJimenez, Juan-Miguel / Davis, Christopher / Boyall, Dean / Fraysse, Damien / Knegtel, Ronald / Settimo, Luca / Young, Stephen / Bolton, Claire / Chiu, Peter / Curnock, Adam et al. | 2012
- 4650
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Cristatumins A–D, new indole alkaloids from the marine-derived endophytic fungus Eurotium cristatum EN-220Du, Feng-Yu / Li, Xiao-Ming / Li, Chun-Shun / Shang, Zhuo / Wang, Bin-Gui et al. | 2012
- 4654
-
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)Hsu, John T.-A. / Yeh, Teng-Kuang / Yen, Shih-Chieh / Chen, Chiung-Tong / Hsieh, Shu-Yi / Hsu, Tsu / Lu, Cheng-Tai / Chen, Chun-Hwa / Chou, Ling-Hui / Chiu, Ching-Hui et al. | 2012
- 4660
-
Novel 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl)acetic acids: Discovery and hit-to-lead evolution of a selective CRTh2 receptor antagonist chemotypePothier, Julien / Riederer, Markus A. / Peter, Oliver / Leroy, Xavier / Valdenaire, Anja / Gnerre, Carmela / Fretz, Heinz et al. | 2012
- 4665
-
Synthesis and evaluation of novel 3a,9a-dihydro-1-ethoxycarbonyl-1-cyclopenteno[5,4-b]benzopyran-4-ones as antifungal agentsGoel, Richa / Sharma, Vishal / Budhiraja, Abhishek / Ishar, Mohan Paul S. et al. | 2012
- 4668
-
Photoinduced DNA cleavage by anthracene based hydroxamic acidsChowdhury, Nilanjana / Dasgupta, Swagata / Pradeep Singh, N.D. et al. | 2012
- 4672
-
Identification of specific features of inhibition of PKCβII and its potential lead by shape-based virtual screening and molecular docking studiesGrewal, Baljinder K. / Elizabeth Sobhia, M. et al. | 2012
- 4672
-
Identification of specific features of inhibition of PKCbII and its potential lead by shape-based virtual screening and molecular docking studiesGrewal, B. K. / Elizabeth Sobhia, M. et al. | 2012
- 4678
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Total synthesis and antifungal activity of (2S,3R)-2-aminododecan-3-olVijai Kumar Reddy, T. / Prabhavathi Devi, B.L.A. / Prasad, R.B.N. / Poornima, M. / Ganesh Kumar, C. et al. | 2012
- 4681
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Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell linesWinum, Jean-Yves / Carta, Fabrizio / Ward, Carol / Mullen, Peter / Harrison, David / Langdon, Simon P. / Cecchi, Alessandro / Scozzafava, Andrea / Kunkler, Ian / Supuran, Claudiu T. et al. | 2012
- 4686
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Novel macrocyclic and acyclic cationic lipids for gene transfer: Synthesis and in vitro evaluationGoldring, William P.D. / Jubeli, Emile / Downs, Rachael A. / Johnston, Adam J.S. / Abdul Khalique, Nada / Raju, Liji / Wafadari, Deena / Pungente, Michael D. et al. | 2012
- 4693
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‘Click’ synthesis of a triazole-based inhibitor of Met functions in cancer cellsColombo, Francesco / Tintori, Cristina / Furlan, Alessandro / Borrelli, Stella / Christodoulou, Michael S. / Dono, Rosanna / Maina, Flavio / Botta, Maurizio / Amat, Mercedes / Bosch, Joan et al. | 2012
- 4697
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Synthesis and antimicrobial activity of amide derivatives of polyether antibiotic—salinomycinHuczyński, Adam / Janczak, Jan / Stefańska, Joanna / Antoszczak, Michał / Brzezinski, Bogumil et al. | 2012
- 4703
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Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitorsXiang, Yang-Fei / Qian, Chui-Wen / Xing, Guo-Wen / Hao, Jing / Xia, Min / Wang, Yi-Fei et al. | 2012
- 4707
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Development and evaluation of multifunctional agents for potential treatment of Alzheimer’s disease: Application to a pyrimidine-2,4-diamine templateMohamed, Tarek / Yeung, Jacky C.K. / Vasefi, Maryam S. / Beazely, Michael A. / Rao, Praveen P.N. et al. | 2012
- 4713
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A new facile synthetic route to [11C]GSK189254, a selective PET radioligand for imaging of CNS histamine H3 receptorWang, Min / Gao, Mingzhang / Steele, Brandon L. / Glick-Wilson, Barbara E. / Brown-Proctor, Clive / Shekhar, Anantha / Hutchins, Gary D. / Zheng, Qi-Huang et al. | 2012
- 4719
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Design and synthesis of potent antagonists containing rigid spirocyclic privileged structures for the CGRP receptorChaturvedula, Prasad V. / Pin, Sokhom / Tholady, George / Conway, Charlie M. / Macor, John E. / Dubowchik, Gene M. et al. | 2012
- 4723
-
The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 1Han, Xiaojun / Civiello, Rita L. / Conway, Charles M. / Cook, Deborah A. / Davis, Carl D. / Macci, Robert / Pin, Sokhom S. / Ren, Shelly X. / Schartman, Richard / Signor, Laura J. et al. | 2012
- 4728
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Estrogenic activity of B-fluorinated o-carborane-1,2-bisphenol synthesized via SNAr reactionOhta, Kiminori / Ogawa, Takumi / Endo, Yasuyuki et al. | 2012
- 4731
-
6β-N-Heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonistsYuan, Yunyun / Stevens, David L. / Braithwaite, Amanda / Scoggins, Krista L. / Bilsky, Edward J. / Akbarali, Hamid I. / Dewey, William L. / Zhang, Yan et al. | 2012
- 4731
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6b-N-Heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonistsYuan, Y. / Stevens, D. L. / Braithwaite, A. / Scoggins, K. L. / Bilsky, E. J. / Akbarali, H. I. / Dewey, W. L. / Zhang, Y. et al. | 2012
- 4735
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Synthesis and cytotoxicity of lupane-type triterpenoid glyceryl estersThibeault, Dominic / Gauthier, Charles / Legault, Jean / Bouchard, Jimmy / Gagné, Louis / Pichette, André et al. | 2012
- 4740
-
Synthesis and structure–activity relationship studies of 1,3-disubstituted 2-propanols as BACE-1 inhibitorsKumar, Arun Babu / Anderson, Jordan Micheal / Melendez, Anthony Lester / Manetsch, Roman et al. | 2012
- 4745
-
Synthesis and evaluation of novel F-18 labeled 4-aminoquinazoline derivatives: Potential PET imaging agents for tumor detectionChen, Yurong / Feng, Man / Li, Shilei / Xu, Jingli / Ning, Hongyu / He, Yong / Wang, Xiao / Ding, Rui / Qi, Chuanmin et al. | 2012
- 4750
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Pyrazole diaminopyrimidines as dual inhibitors of KDR and Aurora B kinasesCurtin, Michael L. / Robin Heyman, H. / Frey, Robin R. / Marcotte, Patrick A. / Glaser, Keith B. / Jankowski, James R. / Magoc, Terrance J. / Albert, Daniel H. / Olson, Amanda M. / Reuter, David R. et al. | 2012
- 4756
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Design, synthesis and structure–activity relationships of 5-alkylaminolquinolines as a novel series of CRF1 receptor antagonistsTakeda, Kunitoshi / Terauchi, Taro / Shin, Kogyoku / Ino, Mitsuhiro / Shibata, Hisashi / Yonaga, Masahiro et al. | 2012
- 4762
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Synthesis and antimalarial activity of calothrixins A and B, and their N-alkyl derivativesMatsumoto, Kohji / Choshi, Tominari / Hourai, Mai / Zamami, Yoshito / Sasaki, Kenji / Abe, Takumi / Ishikura, Minoru / Hatae, Noriyuki / Iwamura, Tatsunori / Tohyama, Shigeo et al. | 2012
- 4765
-
A novel convergent method for the synthesis of a-acyl-g-hydroxylactams and its application in the total synthesis of PI-090 and 091Uchiro, H. / Shionozaki, N. / Kobayakawa, Y. / Nakagawa, H. / Makino, K. et al. | 2012
- 4765
-
A novel convergent method for the synthesis of α-acyl-γ-hydroxylactams and its application in the total synthesis of PI-090 and 091Uchiro, Hiromi / Shionozaki, Nobuhiro / Kobayakawa, Yu / Nakagawa, Hiroko / Makino, Kimiko et al. | 2012
- 4769
-
Symmetrical approach of spiro-pyrazolidinediones as acetyl-CoA carboxylase inhibitorsKamata, Makoto / Yamashita, Tohru / Kina, Asato / Tawada, Michiko / Endo, Satoshi / Mizukami, Atsushi / Sasaki, Masako / Tani, Akiyoshi / Nakano, Yoshihide / Watanabe, Yuuki et al. | 2012
- 4773
-
Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: As a new class of potent antioxidants and antimicrobials-A novel accost to amend biocompatibilityRangaswamy, Javarappa / Vijay Kumar, Honnaiah / Harini, Salakatte Thammaiah / Naik, Nagaraja et al. | 2012
- 4778
-
Synthesis and biological evaluation of novel 4β-(1,3,4-oxadiazole-2-amino)-podophyllotoxin derivativesRen, Jie / Wu, Lin / Xin, Wen Qun / Chen, Xin / Hu, Kun et al. | 2012
- 4778
-
Synthesis and biological evaluation of novel 4b-(1,3,4-oxadiazole-2-amino)-podophyllotoxin derivativesRen, J. / Wu, L. / Xin, W. Q. / Chen, X. / Hu, K. et al. | 2012
- 4783
-
Design, synthesis and biological evaluation of β-carboline derivatives as novel inhibitors targeting B-Raf kinaseXin, Botao / Tang, Weifang / Wang, Yue / Lin, Guowu / Liu, Haichun / Jiao, Yu / Zhu, Yong / Yuan, Haoliang / Chen, Yadong / Lu, Tao et al. | 2012
- 4783
-
Design, synthesis and biological evaluation of b-carboline derivatives as novel inhibitors targeting B-Raf kinaseXin, B. / Tang, W. / Wang, Y. / Lin, G. / Liu, H. / Jiao, Y. / Zhu, Y. / Yuan, H. / Chen, Y. / Lu, T. et al. | 2012
- 4787
-
Triterpenes from Alisma orientalis act as farnesoid X receptor agonistsLin, Hsiang-Ru et al. | 2012
- 4793
-
New triterpenoid saponins from cacti and anti-type I allergy activity of saponins from cactusKakuta, Kazutaka / Baba, Masaki / Ito, Satoru / Kinoshita, Kaoru / Koyama, Kiyotaka / Takahashi, Kunio et al. | 2012
- 4801
-
Steroids from Commiphora mukul display antiproliferative effect against human prostate cancer PC3 cells via induction of apoptosisShen, Tao / Zhang, Li / Wang, Yan-Yan / Fan, Pei-Hong / Wang, Xiao-Ning / Lin, Zhao-Min / Lou, Hong-Xiang et al. | 2012
- 4807
-
Synthesis and in vitro antitubercular activity of 4-aryl/alkylsulfonylmethylcoumarins as inhibitors of Mycobacterium tuberculosisJeyachandran, Malaichamy / Ramesh, Penugonda / Sriram, Dharmarajan / Senthilkumar, Palaniappan / Yogeeswari, Perumal et al. | 2012
- 4810
-
Synthesis of pacidamycin analogues via an Ugi-multicomponent reactionOkamoto, Kazuya / Sakagami, Masahiro / Feng, Fei / Takahashi, Fumiyo / Uotani, Kouichi / Togame, Hiroko / Takemoto, Hiroshi / Ichikawa, Satoshi / Matsuda, Akira et al. | 2012
- 4816
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Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-kB inhibitorsLansdell, T. A. / O'Reilly, S. / Woolliscroft, T. / Azevedo, L. M. / Kahlon, D. K. / Hovde, S. / McCormick, J. J. / Henry, R. W. / Cornicelli, J. A. / Tepe, J. J. et al. | 2012
- 4816
-
Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-κB inhibitorsLansdell, Theresa A. / O’Reilly, Sandra / Woolliscroft, Tracey / Azevedo, Lauren M. / Kahlon, Daljinder K. / Hovde, Stacy / McCormick, J. Justin / Henry, R. William / Cornicelli, Joseph A. / Tepe, Jetze J. et al. | 2012
- 4820
-
Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocyclesMandadapu, Sivakoteswara Rao / Weerawarna, Pathum M. / Gunnam, Mallikarjuna Reddy / Alliston, Kevin R. / Lushington, Gerald H. / Kim, Yunjeong / Chang, Kyeong-Ok / Groutas, William C. et al. | 2012
- 4820
-
Potent inhibition of norovirus 3CL protease by peptidyl a-ketoamides and a-ketoheterocyclesMandadapu, S. R. / Weerawarna, P. M. / Gunnam, M. R. / Alliston, K. R. / Lushington, G. H. / Kim, Y. / Chang, K. O. / Groutas, W. C. et al. | 2012
- 4827
-
CoMSIA and POM analyses of anti-malarial activity of synthetic prodigininesMahajan, Devidas T. / Masand, Vijay H. / Patil, Komalsing N. / Hadda, Taibi Ben / Jawarkar, Rahul D. / Thakur, Sumer D. / Rastija, Vesna et al. | 2012
- 4836
-
Cleavage and protection of locked nucleic acid–modified DNA by restriction endonucleasesCrouzier, Lucile / Dubois, Camille / Wengel, Jesper / Veedu, Rakesh N. et al. | 2012
- 4839
-
Discovery of benzothiazole guanidines as novel inhibitors of thrombin and trypsin IVKarle, Michael / Knecht, Wolfgang / Xue, Yafeng et al. | 2012
- 4844
-
Inhibition of therapeutically important polymerases with high affinity bis-intercalatorsJain, Nitin / Francis, Subhashree / Friedman, Simon H. et al. | 2012
- 4849
-
Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: Clinical compound TD-2749Long, Daniel D. / Armstrong, Scott R. / Beattie, David T. / Choi, Seok-Ki / Fatheree, Paul R. / Gendron, Roland A.L. / Goldblum, Adam A. / Humphrey, Patrick P. / Marquess, Daniel G. / Shaw, Jeng-Pyng et al. | 2012
- 4854
-
Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancerMock, Jason N. / Taliaferro, John P. / Lu, Xiao / Patel, Sravan Kumar / Cummings, Brian S. / Long, Timothy E. et al. | 2012
- 4859
-
Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathwayDeBerardinis, Albert M. / Banerjee, Upasana / Miller, Michele / Lemieux, Steven / Hadden, M.K. et al. | 2012
- 4864
-
Synthesis and evaluation of novel potent HCV NS5A inhibitorsZhang, Hongwang / Zhou, Longhu / Amblard, Franck / Shi, Junxing / Bobeck, Drew R. / Tao, Sijia / McBrayer, Tamara R. / Tharnish, Phillip M. / Whitaker, Tony / Coats, Steven J. et al. | 2012
- 4869
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Identification of a dual d OR antagonist/m OR agonist as a potential therapeutic for diarrhea-predominant Irritable Bowel Syndrome (IBS-d)Breslin, H. J. / Diamond, C. J. / Kavash, R. W. / Cai, C. / Dyatkin, A. B. / Miskowski, T. A. / Zhang, S. P. / Wade, P. R. / Hornby, P. J. / He, W. et al. | 2012
- 4869
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Identification of a dual δ OR antagonist/μ OR agonist as a potential therapeutic for diarrhea-predominant Irritable Bowel Syndrome (IBS-d)Breslin, Henry J. / Diamond, Craig J. / Kavash, Robert W. / Cai, Chaozhong / Dyatkin, Alexey B. / Miskowski, Tamara A. / Zhang, Sui-Po / Wade, Paul R. / Hornby, Pamela J. / He, Wei et al. | 2012
- 4873
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Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp.Feng, Yunjiang / Davis, Rohan A. / Sykes, Melissa L. / Avery, Vicky M. / Quinn, Ronald J. et al. | 2012
- 4877
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Neamphamide B, new cyclic depsipeptide, as an anti-dormant mycobacterial substance from a Japanese marine sponge of Neamphius sp.Yamano, Yoshi / Arai, Masayoshi / Kobayashi, Motomasa et al. | 2012
- 4882
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Conformation study of 2-arylbenzimidazoles as inhibitors of Chlamydia pneumoniae growthSiiskonen, Antti / Keurulainen, Leena / Salin, Olli / Kiuru, Paula / Pohjala, Leena / Vuorela, Pia / Yli-Kauhaluoma, Jari et al. | 2012
- 4887
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Synthesis and biological evaluation of vinyl ether-containing azole derivatives as inhibitors of Trichophyton rubrumWang, Lulu / Yang, Wenge / Wang, Kai / Zhu, Jing / Shen, Fei / Hu, Yonghong et al. | 2012
- 4891
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Synthesis, biological evaluation of 5-carbomethoxymethyl-7-hydroxy-2-pentylchromone, 5-carboethoxymethyl-4′,7-dihydroxyflavone and their analoguesKamal, Ahmed / Murty, J.N.S.R.C. / Viswanath, A. / Sujitha, P. / Ganesh Kumar, C. et al. | 2012
- 4891
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Synthesis, biological evaluation of 5-carbomethoxymethyl-7-hydroxy-2-pentylchromone, 5-carboethoxymethyl-4prime,7-dihydroxyflavone and their analoguesKamal, A. / Murty, J. N. / Viswanath, A. / Sujitha, P. / Ganesh Kumar, C. et al. | 2012
- 4896
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Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitorsZych, Andrew J. / Lam, Sang Q. / Jenkins, David M. / Herr, R. Jason / Ting, Pauline C. / Lee, Joe F. / Kuang, Rongze / Wu, Heping / Kim, David W. / Aslanian, Robert G. et al. | 2012
- 4900
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Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbaceaSrikanth Reddy, T. / Suryakiran, N. / Narasimhulu, M. / Ramesh, D. / Chinni Mahesh, K. / Sai Krishna, A. / Kavitha, P. / Venkateswara Rao, J. / Venkateswarlu, Y. et al. | 2012
- 4907
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Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMOYang, Bin / Hird, Alexander W. / Russell, Daniel John / Fauber, Benjamin P. / Dakin, Les A. / Zheng, Xiaolan / Su, Qibin / Godin, Robert / Brassil, Patrick / Devereaux, Erik et al. | 2012
- IFC
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Editorial board| 2012