Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines (English)
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In:
Bioorganic and Medicinal Chemistry Letters
;
16
, 5
;
1191-1196
;
2005
-
ISSN:
- Article (Journal) / Electronic Resource
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Title:Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines
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Contributors:Ouyang, Xiaohu ( author ) / Piatnitski, Evgueni L. ( author ) / Pattaropong, Vatee ( author ) / Chen, Xiaoling ( author ) / He, Hai-Ying ( author ) / Kiselyov, Alexander S. ( author ) / Velankar, Avdhoot ( author ) / Kawakami, Joel ( author ) / Labelle, Marc ( author ) / Smith, Leon II ( author )
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Published in:Bioorganic and Medicinal Chemistry Letters ; 16, 5 ; 1191-1196
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Publisher:
- New search for: Elsevier Ltd
-
Publication date:2005-11-23
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Size:6 pages
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ISSN:
-
DOI:
-
Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 16, Issue 5
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1091
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Graphical contents list| 2006
- 1111
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Design, synthesis and preliminary biological evaluations of novel amphiphilic drug carriersPérino, Sandrine / Contino-Pépin, Christiane / Jasseron, Sylvain / Rapp, Maryse / Maurizis, Jean-Claude / Pucci, Bernard et al. | 2005
- 1115
-
Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivoYu, Kuo-Long / Wang, Xiangdong Alan / Civiello, Rita L. / Trehan, Ashok K. / Pearce, Bradley C. / Yin, Zhiwei / Combrink, Keith D. / Gulgeze, H. Belgin / Zhang, Yi / Kadow, Kathleen F. et al. | 2005
- 1123
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1,4-Anhydrogalactopyranose is not an intermediate of the mutase catalyzed UDP-galactopyranose/furanose interconversionCaravano, Audrey / Sinaÿ, Pierre / Vincent, Stéphane P. et al. | 2005
- 1126
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Conformational constraint in oxazolidinone antibacterials. Part 2: Synthesis and structure–activity studies of oxa-, aza-, and thiabicyclo[3.1.0]hexylphenyl oxazolidinonesRenslo, Adam R. / Gao, Hongwu / Jaishankar, Priyadarshini / Venkatachalam, Revathy / Gómez, Marcela / Blais, Johanne / Huband, Michael / Vara Prasad, J.V.N. / Gordeev, Mikhail F. et al. | 2005
- 1130
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Optimization of a privileged structure leading to potent and selective human melanocortin subtype-4 receptor ligandsBakshi, Raman K. / Hong, Qingmei / Tang, Rui / Kalyani, Rubana N. / MacNeil, Tanya / Weinberg, David H. / Van der Ploeg, Lex H.T. / Patchett, Arthur A. / Nargund, Ravi P. et al. | 2005
- 1134
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Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: Potent and selective aromatase inhibitorsLézé, Marie-Pierre / Le Borgne, Marc / Pinson, Patricia / Palusczak, Anja / Duflos, Muriel / Le Baut, Guillaume / Hartmann, Rolf W. et al. | 2005
- 1138
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Structure–activity relationships of a-amino acid ligands for the a2δ subunit of voltage-gated calcium channelsMortell, Kathleen H. et al. | 2006
- 1138
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Structure–activity relationships of α-amino acid ligands for the α2δ subunit of voltage-gated calcium channelsMortell, Kathleen H. / Anderson, David J. / Lynch, James J. III / Nelson, Sherry L. / Sarris, Kathy / McDonald, Heath / Sabet, Reza / Baker, Scott / Honore, Prisca / Lee, Chih-Hung et al. | 2005
- 1142
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Phenyl ureas of creatinine as mGluR5 antagonists. A structure–activity relationship study of fenobam analoguesWållberg, Andreas / Nilsson, Karolina / Österlund, Krister / Peterson, Alecia / Elg, Susanne / Raboisson, Patrick / Bauer, Udo / Hammerland, Lance G. / Mattsson, Jan P. et al. | 2005
- 1146
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Potent 2-[(pyrimidin-4-yl)amine}-1,3-thiazole-5-carbonitrile-based inhibitors of VEGFR-2 (KDR) kinaseSisko, John T. / Tucker, Thomas J. / Bilodeau, Mark T. / Buser, Carolyn A. / Ciecko, Patrice A. / Coll, Kathleen E. / Fernandes, Christine / Gibbs, Jackson B. / Koester, Timothy J. / Kohl, Nancy et al. | 2005
- 1151
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Synthesis and structure–activity relationships of novel pyrrolocarbazole lactam analogs as potent and cell-permeable inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)Wells, Gregory J. / Bihovsky, Ron / Hudkins, Robert L. / Ator, Mark A. / Husten, Jean et al. | 2005
- 1156
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Structure–activity studies of quinuclidinone analogs as anti-proliferative agents in lung cancer cell linesMalki, Ahmed / Pulipaka, Aravinda B. / Evans, Susan C. / Bergmeier, Stephen C. et al. | 2005
- 1160
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Synthesis and DNA-binding ability of pyrrolo[2,1-c][1,4]benzodiazepine-azepane conjugatesKamal, Ahmed / Reddy, D. Rajasekhar / Reddy, P.S. Murali Mohan / Rajendar et al. | 2005
- 1164
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Synthesis and antimycobacterial activity of some alkyl [5-(nitroaryl)-1,3,4-thiadiazol-2-ylthio]propionatesForoumadi, Alireza / Kargar, Zahra / Sakhteman, Amirhossein / Sharifzadeh, Zahra / Feyzmohammadi, Robabeh / Kazemi, Mahnoush / Shafiee, Abbas et al. | 2005
- 1168
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Gallium(III) complexes of methyl pyropheophorbide-a as synthetic models for investigation of diastereomerically controlled axial ligation towards chlorophyllsSasaki, Shin-ichi / Mizoguchi, Tadashi / Tamiaki, Hitoshi et al. | 2005
- 1172
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Asymmetric synthesis of the l-fuco-nojirimycin, a nanomolar α-l-fucosidase inhibitorDubernet, Mathieu / Defoin, Albert / Tarnus, Céline et al. | 2005
- 1172
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Asymmetric synthesis of the l-fuco-nojirimycin, a nanomolar a-l-fucosidase inhibitorDubernet, Mathieu et al. | 2006
- 1175
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Imidazo[1,2-a]pyrimidines as functionally selective GABAA ligandsBlackaby, Wesley P. / Atack, John R. / Bromidge, Frances / Castro, José L. / Goodacre, Simon C. / Hallett, David J. / Lewis, Richard T. / Marshall, George R. / Pike, Andrew / Smith, Alison J. et al. | 2005
- 1180
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Stimulation on DNA triplet repeat strand slippage synthesis by the designed spirocyclesXi, Zhen / Ouyang, Di / Mu, Hong-Tao et al. | 2005
- 1185
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Interaction of bulged DNA with leucine-containing mimics of NCS-chromXi, Zhen / Ouyang, Di / Mu, Hong-Tao et al. | 2005
- 1191
-
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell linesOuyang, Xiaohu / Piatnitski, Evgueni L. / Pattaropong, Vatee / Chen, Xiaoling / He, Hai-Ying / Kiselyov, Alexander S. / Velankar, Avdhoot / Kawakami, Joel / Labelle, Marc / Smith, Leon II et al. | 2005
- 1197
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Novel lactam NK1 antagonists with anti-emetic activityHollingworth, Gregory J. / Carlson, Emma J. / Castro, José L. / Chicchi, Gary G. / Clark, Natalie / Cooper, Laura C. / Dirat, Olivier / Salvo, Jerry Di / Elliott, Jason M. / Kilburn, Ruth et al. | 2005
- 1202
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5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure–activity relationship studies of 5-alkylethers and 5-thioethersSakya, Subas M. / Cheng, Hengmiao / Lundy DeMello, Kristin M. / Shavnya, Andrei / Minich, Martha L. / Rast, Bryson / Dutra, Jason / Li, Chao / Rafka, Robert J. / Koss, David A. et al. | 2005
- 1207
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Synthesis and biological evaluation of novel hexahydro-pyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT2C receptor agonistsRichter, Hans G.F. / Adams, D.R. / Benardeau, A. / Bickerdike, M.J. / Bentley, J.M. / Blench, T.J. / Cliffe, I.A. / Dourish, C. / Hebeisen, P. / Kennett, G.A. et al. | 2005
- 1212
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New benzimidazoles as thrombopoietin receptor agonistsSafonov, Igor G. / Heerding, Dirk A. / Keenan, Richard M. / Price, Alan T. / Erickson-Miller, Connie L. / Hopson, Christopher B. / Levin, Jenna L. / Lord, Kenneth A. / Tapley, Peter M. et al. | 2005
- 1217
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The existence of a second allosteric site on the M1 muscarinic acetylcholine receptor and its implications for drug designEspinoza-Fonseca, L. Michel / Trujillo-Ferrara, José G. et al. | 2005
- 1221
-
Heteropoly acids as solid green Brønsted acids for a one-pot synthesis of β-acetamido ketones by Dakin–West reactionRafiee, Ezzat / Tork, Fariba / Joshaghani, M. et al. | 2005
- 1221
-
Heteropoly acids as solid green Brønsted acids for a one-pot synthesis of b-acetamido ketones by Dakin–West reactionRafiee, Ezzat et al. | 2006
- 1227
-
Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membraneJung, Mankil / Tak, Jungae / Chung, Won-Yoon / Park, Kwang-Kyun et al. | 2005
- 1231
-
(+)-12α-Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescensDing, Pei-Lan / Liao, Zhi-Xin / Huang, Hai / Zhou, Pei / Chen, Dao-Feng et al. | 2005
- 1231
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(+)-12a-Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescensDing, Pei-Lan et al. | 2006
- 1236
-
Effects of a-tocopherol and related compounds on reactions involving various organic radicalsPovalishev, V.N. et al. | 2006
- 1236
-
Effects of α-tocopherol and related compounds on reactions involving various organic radicalsPovalishev, V.N. / Polozov, G.I. / Shadyro, O.I. et al. | 2005
- 1240
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Thyroid receptor ligands. Part 5: Novel bicyclic agonist ligands selective for the thyroid hormone receptor βGarcia Collazo, Ana-Maria / Koehler, Konrad F. / Garg, Neeraj / Färnegårdh, Mathias / Husman, Bolette / Ye, Liu / Ljunggren, Jan / Mellström, Karin / Sandberg, Johnny / Grynfarb, Marlena et al. | 2005
- 1240
-
Thyroid receptor ligands. Part 5: Novel bicyclic agonist ligands selective for the thyroid hormone receptor bGarcia Collazo, Ana-Maria et al. | 2006
- 1245
-
Antimicrobial b-peptoids by a block synthesis approachShuey, Steven W. et al. | 2006
- 1245
-
Antimicrobial β-peptoids by a block synthesis approachShuey, Steven W. / Delaney, William J. / Shah, Mukesh C. / Scialdone, Mark A. et al. | 2005
- 1249
-
The cytotoxicity of ortho alkyl substituted 4-X-phenols: A QSAR based on theoretical bond lengths and electron densitiesLoader, R.J. / Singh, N. / O’Malley, P.J. / Popelier, P.L.A. et al. | 2005
- 1255
-
Aminoalkyl phenyl sulfones—a novel series of 5-HT7 receptor ligandsRaubo, Piotr / Beer, Margaret S. / Hunt, Peter A. / Huscroft, Ian T. / London, Clare / Stanton, Josephine A. / Kulagowski, Janusz J. et al. | 2005
- 1259
-
Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolidesFu, Hong / Marquez, Saul / Gu, Xiangrong / Katz, Leonard / Myles, David C. et al. | 2005
- 1267
-
Probing structure/affinity relationships for the Plasmodium falciparum hexose transporter with glucose derivativesFayolle, Martine / Ionita, Marina / Krishna, Sanjeev / Morin, Christophe / Patel, Asha Parbhu et al. | 2005
- 1272
-
Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: Synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cellsWiles, Jason A. / Wang, Qiuping / Lucien, Edlaine / Hashimoto, Akihiro / Song, Yongsheng / Cheng, Jijun / Marlor, Christopher W. / Ou, Yangsi / Podos, Steven D. / Thanassi, Jane A. et al. | 2005
- 1277
-
Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureusWiles, Jason A. / Song, Yongsheng / Wang, Qiuping / Lucien, Edlaine / Hashimoto, Akihiro / Cheng, Jijun / Marlor, Christopher W. / Ou, Yangsi / Podos, Steven D. / Thanassi, Jane A. et al. | 2005
- 1282
-
Synthesis and antitumor activity of simplified ecteinascidin–saframycin analogsLiu, Zhan-Zhu / Wang, Ye / Tang, Ye-Feng / Chen, Shi-Zhi / Chen, Xiao-Guang / Li, Hong-Yan et al. | 2005
- 1286
-
Triaminotriazine DNA helicase inhibitors with antibacterial activityMcKay, Geoffrey A. / Reddy, Ranga / Arhin, Francis / Belley, Adam / Lehoux, Dario / Moeck, Greg / Sarmiento, Ingrid / Parr, Thomas R. / Gros, Philippe / Pelletier, Jerry et al. | 2005
- 1291
-
A topological function based on spectral moments for predicting affinity toward A3 adenosine receptorsGonzález, Maykel Pérez / Terán, Carmen / Teijeira, Marta et al. | 2005
- 1297
-
Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligandsVercouillie, Johnny / Mavel, Sylvie / Galineau, Laurent / Ragusa, Tiziana / Innis, Robert / Kassiou, Michael / Chalon, Sylvie / Dollé, Frédéric / Besnard, Jean-Claude / Guilloteau, Denis et al. | 2005
- 1301
-
CpG DNA/zymosan complex to enhance cytokine secretion owing to the cocktail effectAnada, Takahisa / Okada, Naoko / Minari, Jusaku / Karinaga, Ryouji / Mizu, Masami / Koumoto, Kazuya / Shinkai, Seiji / Sakurai, Kazuo et al. | 2005
- 1305
-
Novel endotoxin-sequestering compounds with terephthalaldehyde-bis-guanylhydrazone scaffoldsKhownium, Kriangsak / Wood, Stewart J. / Miller, Kelly A. / Balakrishna, Rajalakshmi / Nguyen, Thuan B. / Kimbrell, Matthew R. / Georg, Gunda I. / David, Sunil A. et al. | 2005
- 1309
-
Synthesis and biological evaluation of simplified mycothiazole analoguesMahler, Graciela / Serra, Gloria / Dematteis, Sylvia / Saldaña, Jenny / Domínguez, Laura / Manta, Eduardo et al. | 2005
- 1312
-
Alkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agentsCoro, Julieta / Atherton, Richard / Little, Susan / Wharton, Hayley / Yardley, Vanessa / Alvarez, Amaury Jr. / Súarez, Margarita / Pérez, Rolando / Rodríguez, Hortensia et al. | 2005
- 1316
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N-Glycosyl-thiophene-2-carboxamides: Effects on endothelial cell growth in the presence and absence of bFGF—A significant increase in potency using per-O-acetylated sugar analoguesRawe, Sarah L. / Zaric, Violeta / O’ Boyle, Kathy M. / Murphy, Paul V. et al. | 2005
- 1320
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SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitorsHeron, Nicola M. / Anderson, Malcolm / Blowers, David P. / Breed, Jason / Eden, Jonathan M. / Green, Stephen / Hill, George B. / Johnson, Trevor / Jung, Frederic H. / McMiken, Helen H.J. et al. | 2005
- 1324
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Chemiluminescent acridinium-9-carboxamide boronic acid probes: Application to a homogeneous glycated hemoglobin assayAdamczyk, Maciej / Chen, Yon-Yih / Johnson, Donald D. / Mattingly, Phillip G. / Moore, Jeffrey A. / Pan, You / Reddy, Rajarathnam E. et al. | 2005
- 1329
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Antioxidant activity and cytoprotective effect of κ-carrageenan oligosaccharides and their different derivativesYuan, Huamao / Song, Jinming / Zhang, Weiwei / Li, Xuegang / Li, Ning / Gao, Xuelu et al. | 2005
- 1335
-
Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylaseNencka, Radim / Votruba, Ivan / Hřebabecký, Hubert / Tloušt’ová, Eva / Horská, Květa / Masojídková, Milena / Holý, Antonín et al. | 2005
- 1338
-
Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinityZhou, Dahui / Harrison, Boyd L. / Shah, Uresh / Andree, Terrance H. / Hornby, Geoffrey A. / Scerni, Rosemary / Schechter, Lee E. / Smith, Deborah L. / Sullivan, Kelly M. / Mewshaw, Richard E. et al. | 2005
- 1342
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From pyrroles to pyrrolo[1,2-a]pyrazinones: A new class of mGluR1 antagonistsMicheli, Fabrizio / Cavanni, Paolo / Di Fabio, Romano / Marchioro, Carla / Donati, Daniele / Faedo, Stefania / Maffeis, Micaela / Sabbatini, Fabio Maria / Tranquillini, Maria Elvira et al. | 2005
- 1346
-
Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitorsXu, Jinyou / Wei, Lan / Mathvink, Robert / Edmondson, Scott D. / Mastracchio, Anthony / Eiermann, George J. / He, Huaibing / Leone, Joseph F. / Leiting, Barbara / Lyons, Kathryn A. et al. | 2005
- 1350
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Design, synthesis, and structure–activity relationship of novel thiophene derivatives for b-amyloid plaque imagingChandra, Rajesh et al. | 2006
- 1350
-
Design, synthesis, and structure–activity relationship of novel thiophene derivatives for β-amyloid plaque imagingChandra, Rajesh / Kung, Mei-Ping / Kung, Hank F. et al. | 2005
- 1353
-
Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: Protein structure-guided design and SARRichardson, Christine M. / Williamson, Douglas S. / Parratt, Martin J. / Borgognoni, Jenifer / Cansfield, Andrew D. / Dokurno, Pawel / Francis, Geraint L. / Howes, Rob / Moore, Jonathan D. / Murray, James B. et al. | 2005
- 1358
-
Synthesis and SAR of 1,2-trans-(1-hydroxy-3-phenylprop-1-yl)cyclopentane carboxamide derivatives, a new class of sodium channel blockersOk, Dong / Li, Chunshi / Abbadie, Catherine / Felix, John P. / Fisher, Michael H. / Garcia, Maria L. / Kaczorowski, Gregory J. / Lyons, Kathryn A. / Martin, William J. / Priest, Birgit T. et al. | 2005
- 1362
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Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonistsHoffmann, Torsten / Bös, Michael / Stadler, Heinz / Schnider, Patrick / Hunkeler, Walter / Godel, Thierry / Galley, Guido / Ballard, Theresa M. / Higgins, Guy A. / Poli, Sonia M. et al. | 2005
- 1366
-
Design, synthesis, and evaluation of novel 6-chloro-/fluorochromone derivatives as potential topoisomerase inhibitor anticancer agentsIshar, M.P.S. / Singh, Gurpinder / Singh, Satyajit / Sreenivasan, K.K. / Singh, Gurmit et al. | 2005
- 1371
-
Identification of phosphodiesterase-1 and 5 dual inhibitors by a ligand-based virtual screening optimized for lead evolutionYamazaki, Kazuto / Kusunose, Naoto / Fujita, Katsuya / Sato, Hideshi / Asano, Shigehiro / Dan, Akihito / Kanaoka, Masaharu et al. | 2005
- 1380
-
Synthesis and antihyperglycemic evaluation of various protoberberine derivativesBian, Xiaoli / He, Langchong / Yang, Guangde et al. | 2005
- 1384
-
Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing powerFerreira, Isabel C.F.R. / Queiroz, Maria-João R.P. / Vilas-Boas, Miguel / Estevinho, Letı́cia M. / Begouin, Agathe / Kirsch, Gilbert et al. | 2005
- 1388
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Sarcosine based indandione hGlyT1 inhibitorsThomson, Christopher G. / Duncan, Karen / Fletcher, Stephen R. / Huscroft, Ian T. / Pillai, Gopalan / Raubo, Piotr / Smith, Alison J. / Stead, Darren et al. | 2005
- 1392
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New Gly-Pro-Glu (GPE) analogues: Expedite solid-phase synthesis and biological activityAlonso De Diego, Sergio A. / Gutiérrez-Rodríguez, Marta / Pérez de Vega, M. Jesús / Casabona, Diego / Cativiela, Carlos / González-Muñiz, Rosario / Herranz, Rosario / Cenarruzabeitia, Edurne / Frechilla, Diana / Río, Joaquín Del et al. | 2005
- 1397
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Design and synthesis of 2′-anilino-4,4′-bipyridines as selective inhibitors of c-Jun N-terminal kinase-3Swahn, Britt-Marie / Xue, Yafeng / Arzel, Erwan / Kallin, Elisabet / Magnus, Angelika / Plobeck, Niklas / Viklund, Jenny et al. | 2005
- 1402
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Synthesis and biological characterization of [3H] (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(4-chlorophenyl)-methanone, the first radiolabelled adenosine A1 allosteric enhancerBaraldi, Pier Giovanni / Pavani, Maria Giovanna / Leung, Edward / Moorman, Allan R. / Varani, Katia / Vincenzi, Fabrizio / Borea, Pier Andrea / Romagnoli, Romeo et al. | 2005
- 1405
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In silico fragment-based discovery of DPP-IV S1 pocket bindersRummey, Christian / Nordhoff, Sonja / Thiemann, Meinolf / Metz, Günther et al. | 2005
- 1410
-
Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding proteinShibata, Aya / Ueno, Yoshihito / Shinbo, Koichiro / Nakanishi, Masayuki / Matsuda, Akira / Kitade, Yukio et al. | 2005
- 1414
-
Anion of hypericin is crucial to understanding the photosensitive features of the pigmentShen, Liang / Ji, Hong-Fang / Zhang, Hong-Yu et al. | 2005
- 1418
-
Antiarrhythmic activity of 4,6-di(het)aryl-5-nitro-3,4-dihydropyrimidin-(1H)-2-ones and its effects on arterial pressure in ratsBryzgalov, Arkadiy O. / Dolgikh, Margarita P. / Sorokina, Irina V. / Tolstikova, Tatiana G. / Sedova, Valentina F. / Shkurko, Oleg P. et al. | 2005
- 1421
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Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitorsAsaki, Tetsuo / Sugiyama, Yukiteru / Hamamoto, Taisuke / Higashioka, Masaya / Umehara, Masato / Naito, Haruna / Niwa, Tomoko et al. | 2005
- 1426
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Protein tyrosine phosphatase 1B inhibitors from Morus root barkCui, Long / Na, MinKyun / Oh, Hyuncheol / Bae, Eun Young / Jeong, Dae Gwin / Ryu, Seong Eon / Kim, Sohee / Kim, Bo Yeon / Oh, Won Keun / Ahn, Jong Seog et al. | 2005
- 1430
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4-Methylideneisoxazolidin-5-ones—A new class of α-methylidene-γ-lactones with high cytostatic activityJanecki, Tomasz / Wąsek, Tomasz / Różalski, Marek / Krajewska, Urszula / Studzian, Kazimierz / Janecka, Anna et al. | 2005
- 1430
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4-Methylideneisoxazolidin-5-ones—A new class of a-methylidene-g-lactones with high cytostatic activityJanecki, Tomasz et al. | 2006
- 1434
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Designing rapid onset selective serotonin re-uptake inhibitors. Part 1: Structure–activity relationships of substituted (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthaleneamineMiddleton, Donald S. / Andrews, Mark / Glossop, Paul / Gymer, Geoffrey / Jessiman, Alan / Johnson, Patrick S. / MacKenny, Malcolm / Pitcher, Michael J. / Rooker, Tony / Stobie, Alan et al. | 2005
- 1440
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Hetaryl imidazoles: A novel dual inhibitors of VEGF receptors I and IIKiselyov, Alexander S. / Semenova, Marina / Semenov, Victor V. et al. | 2005
- 1445
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Inactivation of medium-chain acyl-CoA dehydrogenase by oct-4-en-2-ynoyl-CoAZeng, Jia / Deng, Guisheng / Yu, Wenhua / Li, Ding et al. | 2005
- 1449
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Erratum to “Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors” [Bioorg. Med. Chem. Lett. 15 (2005) 5453–5458]Shi, Yan / Zhang, Jing / Stein, Philip D. / Shi, Mengxiao / O’Connor, Stephen P. / Bisaha, Sharon N. / Li, Chi / Atwal, Karnail S. / Bisacchi, Gregory S. / Sitkoff, Doree et al. | 2005
- CO2
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Editorial board| 2006
- I
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Instructions to contributors| 2006