Verfahren zum Induzieren der Nukleation in einer Probe und System hierfür (German)

2011
  • Patent  /  Electronic Resource

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Inducing nucleation in a sample, preferably a biological sample, using an external element, comprises providing the sample in a freezing chamber having device for controlled cooling of the freezing chamber and a sensor for measuring the temperature of the sample in the chamber, providing the external element, which is moved automatically and cooled by a refrigeration system to less than 4[deg] C, preferably less than 0[deg] C, and cooling the sample in the freezing chamber and determining the temperature of the sample. The external element is automatically contacted with the sample. Inducing nucleation in a sample, preferably a biological sample, using an external element, comprises (a) providing the sample in a freezing chamber having device for controlled cooling of the freezing chamber and a sensor for measuring the temperature of the sample in the chamber, (b) providing the external element, which is moved automatically and cooled by a refrigeration system to less than 4[deg] C, preferably less than 0[deg] C, and (c) cooling the sample in the freezing chamber and determining the temperature of the sample in the freezing chamber. The external element is automatically contacted with the sample at a predetermined temperature of the sample for inducing the nucleation. Independent claims are also included for: (1) a system for inducing the nucleation in the sample, preferably biological sample, comprising the freezing chamber for receiving the sample having a sensor for measuring the temperature of the sample, a device for contacting the external element cooled to less than 4[deg] C, preferably less than 0[deg] C, having sample in the freezing chamber, and the control unit for controlling the movement of the external element; and (2) a computer program comprising program code means, preferably stored on a machine-readable carrier, for performing the above method, when the computer program is executed on computer.

Die vorliegende Erfindung betrifft ein Verfahren zum Induzieren der Nukleation in einer Probe, insbesondere einer biologischen Probe. In einem weiteren Aspekt richtet sich die Erfindung auf ein System zum Induzieren der Nukleation in einer Probe, wobei die Nukleation automatisch durch Einbringen eines externen Elementes ausgelöst wird.

  • Title:
    Verfahren zum Induzieren der Nukleation in einer Probe und System hierfür
  • Additional title:
    Inducing nucleation in sample, preferably biological sample, using external element, comprises providing sample in freezing chamber, providing external element, and cooling and determining temperature of sample in freezing chamber
  • Patent number:
    DE102011108251
  • Application date:
    2011-07-22
  • Patent applicant:
  • Patent family:
  • Author / Creator:
  • Publisher:
    Europäisches Patentamt
  • Year of publication:
    2011
  • Type of media:
    Patent
  • Type of material:
    Electronic Resource
  • Language:
    German
  • Classification:
    IPC:    A01N Konservieren von Körpern von Menschen, Tieren, Pflanzen oder deren Teilen, PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF / B01L Chemische oder physikalische Laboratoriumsgeräte zum allgemeinen Gebrauch, CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE / G01N Untersuchen oder Analysieren von Stoffen durch Bestimmen ihrer chemischen oder physikalischen Eigenschaften, INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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