β-Lactam congeners of orlistat as inhibitors of fatty acid synthase (English)
- New search for: Zhang, Wei
- New search for: Zhang, Wei
- New search for: Richardson, Robyn D.
- New search for: Chamni, Supakarn
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In:
Bioorganic & medicinal chemistry letters
;
18
, 7
; 2491-2494
;
2008
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ISSN:
- Article (Journal) / Print
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Title:β-Lactam congeners of orlistat as inhibitors of fatty acid synthase
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Contributors:
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Published in:Bioorganic & medicinal chemistry letters ; 18, 7 ; 2491-2494
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Publisher:
- New search for: Elsevier
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Place of publication:Amsterdam [u.a.]
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Publication date:2008
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ISSN:
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ZDBID:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 35.70 / 44.33 / 44.42
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Source:
Table of contents – Volume 18, Issue 7
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2231
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Graphical contents list| 2008
- 2246
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Rhodamine-based fluorogenic probe for imaging biological thiolShibata, Aya / Furukawa, Kazuhiro / Abe, Hiroshi / Tsuneda, Satoshi / Ito, Yoshihiro et al. | 2008
- 2250
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Discovery of novel PRL-3 inhibitors based on the structure-based virtual screeningPark, Hwangseo / Jung, Suk-Kyeong / Jeong, Dae Gwin / Ryu, Seong Eon / Kim, Seung Jun et al. | 2008
- 2256
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Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824Li, Xiaojin / Manjunatha, Ujjini H. / Goodwin, Michael B. / Knox, John E. / Lipinski, Christopher A. / Keller, Thomas H. / Barry, Clifton E. III / Dowd, Cynthia S. et al. | 2008
- 2263
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N-Alkylated galanthamine derivatives: Potent acetylcholinesterase inhibitors from Leucojum aestivumBerkov, Strahil / Codina, Carles / Viladomat, Francesc / Bastida, Jaume et al. | 2008
- 2267
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Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substratesInnocenti, Alessio / Scozzafava, Andrea / Parkkila, Seppo / Puccetti, Luca / De Simone, Giuseppina / Supuran, Claudiu T. et al. | 2008
- 2272
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Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activityBolognesi, Maria Laura / Lizzi, Federica / Perozzo, Remo / Brun, Reto / Cavalli, Andrea et al. | 2008
- 2277
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Synthesis, anti-HIV-1 activity, and modeling studies of N-3 Boc TSAO compoundTomassi, Cyrille / Van Nhien, Albert Nguyen / Marco-Contelles, José / Balzarini, Jan / Pannecouque, Christophe / De Clercq, Erik / Soriano, Elena / Postel, Denis et al. | 2008
- 2282
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Synthesis of 17b-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell linesProvencher-Mandeville, J. / Descoteaux, C. / Mandal, S. K. / Leblanc, V. / Asselin, E. / Berube, G. et al. | 2008
- 2282
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Synthesis of 17β-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell linesProvencher-Mandeville, Josée / Descôteaux, Caroline / Mandal, Sanat K. / Leblanc, Valérie / Asselin, Éric / Bérubé, Gervais et al. | 2008
- 2288
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Diamine derivatives containing imidazolidinylidene propanedinitrile as a new class of histamine H3 receptor antagonists. Part ISasho, Setsuya / Seishi, Takashi / Kawamura, Mariko / Hirose, Ryo / Toki, Shinichiro / Shimada, Jun-ich et al. | 2008
- 2292
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Synthesis and biological evaluation of 3,5-diaminoindazoles as cyclin-dependent kinase inhibitorsLee, Jinho / Choi, Hwangeun / Kim, Kyoung-Hee / Jeong, Shinwu / Park, Jong-Wook / Baek, Chul-Su / Lee, Sei-Hee et al. | 2008
- 2296
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Chemically modified oligonucleotides with efficient RNase H responseVester, Birte / Boel, Anne Marie / Lobedanz, Sune / Babu, B. Ravindra / Raunkjær, Michael / Lindegaard, Dorthe / Raunak / Hrdlicka, Patrick J. / Højland, Torben / Sharma, Pawan K. et al. | 2008
- 2301
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Synthesis and antihyperglycemic activity of novel N-acyl-2-arylethylamines and N-acyl-3-coumarylaminesDwivedi, Atma P. / Kumar, Shailesh / Varshney, Vandana / Singh, Amar B. / Srivastava, Arvind K. / Sahu, Devi P. et al. | 2008
- 2306
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Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbonesAviñó, Anna / Navarro, Isabel / Farrera-Sinfreu, Josep / Royo, Miriam / Aymamí, Juan / Delgado, Antonio / Llebaria, Amadeu / Albericio, Fernando / Eritja, Ramon et al. | 2008
- 2311
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Investigation of novel 7,8-disubstituted-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-ones as potent Chk1 inhibitorsHasvold, Lisa A. / Wang, Le / Przytulinska, Magdalena / Xiao, Zhan / Chen, Zehan / Gu, Wen-Zhen / Merta, Philip J. / Xue, John / Kovar, Peter / Zhang, Haiying et al. | 2008
- 2316
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Deconstructing cytisine: The syntheses of (±)-cyfusine and (±)-cyclopropylcyfusine, fused ring analogs of cytisineYohannes, Daniel / Procko, Kristen / Lebel, Lorraine A. / Fox, Carol B. / O’Neill, Brian T. et al. | 2008
- 2320
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Increasing permeability of phospholipid bilayer membranes to alanine with synthetic α-aminophosphonate carriersDanila, Delia C. / Wang, Xinyan / Hubble, Heather / Antipin, Igor S. / Pinkhassik, Eugene et al. | 2008
- 2320
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Increasing permeability of phospholipid bilayer membranes to alanine with synthetic a-aminophosphonate carriersDanila, D. C. / Wang, X. / Hubble, H. / Antipin, I. S. / Pinkhassik, E. et al. | 2008
- 2324
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Discovery of 2-amino-6-carboxamidobenzothiazoles as potent Lck inhibitorsHuang, Shenlin / Liu, Zuosheng / Tian, Shin-Shay / Sandberg, Mark / Spalding, Tracy A. / Romeo, Russell / Iskandar, Maya / Wang, Zhiliang / Karanewsky, Donald / He, Yun et al. | 2008
- 2329
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Synthesis and antibacterial activity of littorachalcone and related diphenyl ethersKraus, George A. / Kumar, Ganesh / Phillips, Gregory / Michalson, Kris / Mangano, Maria et al. | 2008
- 2333
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Meclonazepam analogues as potential new antihelmintic agentsMahajan, Aman / Kumar, Vipan / Mansour, Nuha R.N. / Bickle, Quentin / Chibale, Kelly et al. | 2008
- 2337
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Synthesis of novel N-diazeniumdiolates based on hyperbranched polyethersKou, Yuxia / Wan, Ajun et al. | 2008
- 2342
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Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogensPeriyasami, Govindasami / Raghunathan, Raghavachary / Surendiran, Gangadharan / Mathivanan, Narayanasamy et al. | 2008
- 2346
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Pharmacophore identification of Raf-1 kinase inhibitorsZhu, Tian / Jiao, Yu / Chen, Ya-Dong / Wang, Xuan / Li, Hui-Fang / Zhang, Lu-Yong / Lu, Tao et al. | 2008
- 2351
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Synthesis of novel analogues of (+)-varitriol via olefin cross-metathesis reactionNagarapu, Lingaiah / Paparaju, Venkateswarlu / Satyender, Apuri et al. | 2008
- 2355
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Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitorsHuang, Hui / Hutta, Daniel A. / Hu, Huaping / DesJarlais, Renee L. / Schubert, Carsten / Petrounia, Ioanna P. / Chaikin, Margery A. / Manthey, Carl L. / Player, Mark R. et al. | 2008
- 2362
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Structure-based design and synthesis of benzimidazole derivatives as dipeptidyl peptidase IV inhibitorsWallace, Michael B. / Feng, Jun / Zhang, Zhiyuan / Skene, Robert J. / Shi, Lihong / Caster, Christopher L. / Kassel, Daniel B. / Xu, Rongda / Gwaltney, Stephen L. II et al. | 2008
- 2368
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TIE-2/VEGF-R2 SAR and in vitro activity of C3-acyl dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole analogsUnderiner, Ted L. / Ruggeri, Bruce / Aimone, Lisa / Albom, Mark / Angeles, Thelma / Chang, Hong / Hudkins, Robert L. / Hunter, Kathryn / Josef, Kurt / Robinson, Candy et al. | 2008
- 2373
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Synthesis of barbiturate-based methionine aminopeptidase-1 inhibitorsHaldar, Manas K. / Scott, Michael D. / Sule, Nitesh / Srivastava, D.K. / Mallik, Sanku et al. | 2008
- 2377
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Incorporation of positively charged ribonucleic guanidine linkages into oligodeoxyribonucleotides: Development of potent antisense agentsPark, Myunji / Canzio, Daniele / Bruice, Thomas C. et al. | 2008
- 2385
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Tetrazole-biarylpyrazole derivatives as cannabinoid CB1 receptor antagonistsKang, Suk Youn / Lee, Sung-Han / Seo, Hee Jeong / Jung, Myung Eun / Ahn, Kwangwoo / Kim, Jeongmin / Lee, Jinhwa et al. | 2008
- 2390
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Aryl–indolyl maleimides as inhibitors of CaMKIIδ. Part 1: SAR of the aryl regionLevy, Daniel E. / Wang, Dan-Xiong / Lu, Qing / Chen, Zheng / Perumattam, John / Xu, Yong-jin / Liclican, Albert / Higaki, Jeffrey / Dong, Hanmin / Laney, Maureen et al. | 2008
- 2390
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Aryl-indolyl maleimides as inhibitors of CaMKIId. Part 1: SAR of the aryl regionLevy, D. E. / Wang, D. X. / Lu, Q. / Chen, Z. / Perumattam, J. / Xu, Y. j. / Liclican, A. / Higaki, J. / Dong, H. / Laney, M. et al. | 2008
- 2395
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Aryl-indolyl maleimides as inhibitors of CaMKIIδ. Part 2: SAR of the amine tetherLevy, Daniel E. / Wang, Dan-Xiong / Lu, Qing / Chen, Zheng / Perumattam, John / Xu, Yong-jin / Higaki, Jeffrey / Dong, Hanmin / Liclican, Albert / Laney, Maureen et al. | 2008
- 2395
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Aryl-indolyl maleimides as inhibitors of CaMKIId. Part 2: SAR of the amine tetherLevy, D. E. / Wang, D. X. / Lu, Q. / Chen, Z. / Perumattam, J. / Xu, Y. j. / Higaki, J. / Dong, H. / Liclican, A. / Laney, M. et al. | 2008
- 2399
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Aryl–indolyl maleimides as inhibitors of CaMKIIδ. Part 3: Importance of the indole orientationLu, Qing / Chen, Zheng / Perumattam, John / Wang, Dan-Xiong / Liang, Weiling / Xu, Yong-jin / Do, Steven / Bonaga, Llorente / Higaki, Jeffrey / Dong, Hanmin et al. | 2008
- 2399
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Aryl-indolyl maleimides as inhibitors of CaMKIId. Part 3: Importance of the indole orientationLu, Q. / Chen, Z. / Perumattam, J. / Wang, D. X. / Liang, W. / Xu, Y. j. / Do, S. / Bonaga, L. / Higaki, J. / Dong, H. et al. | 2008
- 2404
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Pyrimidine-based inhibitors of CaMKIIδMavunkel, Babu / Xu, Yong-jin / Goyal, Bindu / Lim, Don / Lu, Qing / Chen, Zheng / Wang, Dan-Xiong / Higaki, Jeffrey / Chakraborty, Indrani / Liclican, Albert et al. | 2008
- 2404
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Pyrimidine-based inhibitors of CaMKIIdMavunkel, B. / Xu, Y. j. / Goyal, B. / Lim, D. / Lu, Q. / Chen, Z. / Wang, D. X. / Higaki, J. / Chakraborty, I. / Liclican, A. et al. | 2008
- 2409
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Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitorsEdmondson, Scott D. / Wei, Lan / Xu, Jinyou / Shang, Jackie / Xu, Shiyao / Pang, Jianmei / Chaudhary, Ashok / Dean, Dennis C. / He, Huaibing / Leiting, Barbara et al. | 2008
- 2414
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Lead identification of 2-iminobenzimidazole antagonists of the chemokine receptor CXCR3Hayes, Martin E. / Breinlinger, Eric C. / Wallace, Grier A. / Grongsaard, Pintipa / Miao, Wenyan / McPherson, Michael J. / Stoffel, Robert H. / Green, David W. / Roth, Gregory P. et al. | 2008
- 2420
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Synthesis and study of antiviral and anti-radical properties of aminophenol derivativesShadyro, O. / Ksendzova, G. / Polozov, G. / Sorokin, V. / Boreko, E. / Savinova, O. / Dubovik, B. / Bizunok, N. et al. | 2008
- 2424
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Targeting gastrin-releasing peptide receptors of prostate cancer cells for photodynamic therapy with a phthalocyanine–bombesin conjugateDubuc, Céléna / Langlois, Réjean / Bénard, François / Cauchon, Nicole / Klarskov, Klaus / Tone, Paul / van Lier, Johan E. et al. | 2008
- 2428
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Sulfonamidolactam inhibitors of coagulation factor XaSmallheer, Joanne M. / Wang, Shuaige / Laws, Mia L. / Nakajima, Suanne / Hu, Zilun / Han, Wei / Jacobson, Irina / Luettgen, Joseph M. / Rossi, Karen A. / Rendina, Alan R. et al. | 2008
- 2434
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Solid-phase synthesis of new pyrrolobenzodiazepine–chalcone conjugates: DNA-binding affinity and anticancer activityKamal, Ahmed / Shankaraiah, N. / Prabhakar, S. / Reddy, Ch. Ratna / Markandeya, N. / Reddy, K. Laxma / Devaiah, V. et al. | 2008
- 2440
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Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbonesFarrera-Sinfreu, Josep / Aviñó, Anna / Navarro, Isabel / Aymamí, Juan / Beteta, Natàlia G. / Varón, Sònia / Pérez-Tomás, Ricardo / Castillo-Avila, Wilmar / Eritja, Ramon / Albericio, Fernando et al. | 2008
- 2445
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Glycosyl and polyalcoholic prodrugs of lonidamineGiorgioni, G. / Ruggieri, S. / Di Stefano, A. / Sozio, P. / Cinque, B. / Di Marzio, L. / Santoni, G. / Claudi, F. et al. | 2008
- 2451
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Xylose as a carrier for boron containing compoundsJacobsson, Mårten / Winander, Cecilia / Mani, Katrin / Ellervik, Ulf et al. | 2008
- 2455
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Synthesis and anti-protozoal activity of C2-substituted polyazamacrocyclesReid, Caroline M. / Ebikeme, Charles / Barrett, Michael P. / Patzewitz, Eva-Maria / Müller, Sylke / Robins, David J. / Sutherland, Andrew et al. | 2008
- 2459
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Fluorination of triptolide and its analogues and their cytotoxicityAoyagi, Yutaka / Hitotsuyanagi, Yukio / Hasuda, Tomoyo / Matsuyama, Saki / Fukaya, Haruhiko / Takeya, Koichi / Aiyama, Ritsuo / Matsuzaki, Takeshi / Hashimoto, Shusuke et al. | 2008
- 2464
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Antioxidant capacity of BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran, and uric acid as evaluated by ORAC method and inhibition of lipid peroxidationNiki, Etsuo / Fukuhara, Akiko / Omata, Yo / Saito, Yoshiro / Yoshida, Yasukazu et al. | 2008
- 2467
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Inhibitors of anthrax lethal factor based upon N-oleoyldopamineGaddis, Brandon D. / Rubert Pérez, Charles M. / Chmielewski, Jean et al. | 2008
- 2471
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Renin inhibition activity by chitooligosaccharidesPark, Pyo-Jam / Ahn, Chang-Bum / Jeon, You-Jin / Je, Jae-Young et al. | 2008
- 2475
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1-Aryl-tetrahydroisoquinoline analogs as active anti-HIV agents in vitroCheng, Pi / Huang, Ning / Jiang, Zhi-Yong / Zhang, Quan / Zheng, Yong-Tang / Chen, Ji-Jun / Zhang, Xue-Mei / Ma, Yun-Bao et al. | 2008
- 2479
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Docking-based 3D-QSAR study for 11β-HSD1 inhibitorsLee, Jin Hee / Kang, Nam Sook / Yoo, Sung-Eun et al. | 2008
- 2479
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Docking-based 3D-QSAR study for 11b-HSD1 inhibitorsLee, J. H. / Kang, N. S. / Yoo, S. E. et al. | 2008
- 2491
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β-Lactam congeners of orlistat as inhibitors of fatty acid synthaseZhang, Wei / Richardson, Robyn D. / Chamni, Supakarn / Smith, Jeffrey W. / Romo, Daniel et al. | 2008
- 2491
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b-Lactam congeners of orlistat as inhibitors of fatty acid synthaseZhang, W. / Richardson, R. D. / Chamni, S. / Smith, J. W. / Romo, D. et al. | 2008
- 2495
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Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)Radanyi, Christine / Le Bras, Gaëlle / Messaoudi, Samir / Bouclier, Céline / Peyrat, Jean-François / Brion, Jean-Daniel / Marsaud, Véronique / Renoir, Jack-Michel / Alami, Mouâd et al. | 2008
- 2499
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Sugar Chips immobilized with synthetic sulfated disaccharides of heparin/heparan sulfate partial structureWakao, Masahiro / Saito, Akihiro / Ohishi, Koh / Kishimoto, Yuko / Nishimura, Tomoaki / Sobel, Michael / Suda, Yasuo et al. | 2008
- 2505
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A novel cholic acid-based contrast enhancement agent for targeted MRIChong, Hyun-Soon / Song, Hyun A. / Lim, Sooyoun / Macrenaris, Keith / Ma, Xiang / Lee, Haisung / Bui, Phuong / Meade, Thomas et al. | 2008
- 2509
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Selective cell adhesion inhibitors: Barbituric acid based α4β7—MAdCAM inhibitorsHarriman, Geraldine C. / Brewer, Matthias / Bennett, Robert / Kuhn, Cyrille / Bazin, Marc / Larosa, Greg / Skerker, Paul / Cochran, Nancy / Gallant, Debra / Baxter, Deborah et al. | 2007
- 2509
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Selective cell adhesion inhibitors: Barbituric acid based a4b7-MAdCAM inhibitorsHarriman, G. C. / Brewer, M. / Bennett, R. / Kuhn, C. / Bazin, M. / Larosa, G. / Skerker, P. / Cochran, N. / Gallant, D. / Baxter, D. et al. | 2008
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Instructions to contributors| 2008
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