A novel series of IKKβ inhibitors part II: Description of a potent and pharmacologically active series of analogs (English)
- New search for: Cushing, Timothy D.
- New search for: Cushing, Timothy D.
- New search for: Baichwal, Vijay
- New search for: Berry, Karen
- New search for: Billedeau, Roland
- New search for: Bordunov, Viola
- New search for: Broka, Chris
- New search for: Browner, Michelle F.
- New search for: Cardozo, Mario
- New search for: Cheng, Peng
- New search for: Clark, David
- New search for: Dalrymple, Stacie
- New search for: DeGraffenreid, Michael
- New search for: Gill, Adrian
- New search for: Hao, Xiaolin
- New search for: Hawley, Ronald C.
- New search for: He, Xiao
- New search for: Labadie, Sharada S.
- New search for: Labelle, Marc
- New search for: Lehel, Csaba
- New search for: Lu, Pu-Ping
- New search for: McIntosh, Joel
- New search for: Miao, Shichang
- New search for: Parast, Camran
- New search for: Shin, Youngsook
- New search for: Sjogren, Eric B.
- New search for: Smith, Marie-Louise
- New search for: Talamas, Francisco X.
- New search for: Tonn, George
- New search for: Walker, Keith M.
- New search for: Walker, Nigel P.C.
- New search for: Wesche, Holger
- New search for: Whitehead, Chris
- New search for: Wright, Matt
- New search for: Jaen, Juan C.
In:
Bioorganic & medicinal chemistry letters
;
21
, 1
; 423-427
;
2011
-
ISSN:
- Article (Journal) / Print
-
Title:A novel series of IKKβ inhibitors part II: Description of a potent and pharmacologically active series of analogs
-
Contributors:Cushing, Timothy D. ( author ) / Baichwal, Vijay / Berry, Karen / Billedeau, Roland / Bordunov, Viola / Broka, Chris / Browner, Michelle F. / Cardozo, Mario / Cheng, Peng / Clark, David
-
Published in:Bioorganic & medicinal chemistry letters ; 21, 1 ; 423-427
-
Publisher:
- New search for: Elsevier
-
Place of publication:Amsterdam [u.a.]
-
Publication date:2011
-
ISSN:
-
ZDBID:
-
Type of media:Article (Journal)
-
Type of material:Print
-
Language:English
- New search for: 35.70 / 44.33 / 44.42
- Further information on Basic classification
-
Keywords:
-
Classification:
-
Source:
Table of contents – Volume 21, Issue 1
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1
-
Graphical contents list| 2010
- 34
-
Novel 6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene analogues as potent and selective 5-HT2C agonists for the treatment of metabolic disordersTye, Heather / Mueller, Stephan G. / Prestle, Juergen / Scheuerer, Stefan / Schindler, Marcus / Nosse, Bernd / Prevost, Natacha / Brown, Christopher J. / Heifetz, Alexander / Moeller, Clemens et al. | 2010
- 38
-
Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligandsBanister, Samuel D. / Moussa, Iman A. / Beinat, Corinne / Reynolds, Aaron J. / Schiavini, Paolo / Jorgensen, William T. / Kassiou, Michael et al. | 2010
- 42
-
Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT7 antagonistsRudolph, Dale A. / Dvorak, Curt A. / Dvorak, Lisa / Nepomuceno, Diane / Bonaventure, Pascal / Lovenberg, Timothy W. / Carruthers, Nicholas I. et al. | 2010
- 45
-
PEGylated derivatives of cystamine as enhanced treatments for nephropathic cystinosisOmran, Ziad / Kay, Graeme / Salvo, Alberto Di / Knott, Rachel M. / Cairns, Donald et al. | 2010
- 48
-
The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanesPurushotham, Madhusudhan / Sheri, Anjaneyulu / Pham-Huu, Duy-Phong / Madras, Bertha K. / Janowsky, Aaron / Meltzer, Peter C. et al. | 2010
- 52
-
Antitumor agents 279. Structure–activity relationship and in vivo studies of novel 2-(furan-2-yl)naphthalen-1-ol (FNO) analogs as potent and selective anti-breast cancer agentsDong, Yizhou / Nakagawa-Goto, Kyoko / Lai, Chin-Yu / Kim, Yoon / Morris-Natschke, Susan L. / Lee, Eva Y.-H.P. / Bastow, Kenneth F. / Lee, Kuo-Hsiung et al. | 2010
- 58
-
Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndromeManning, David D. / Cioffi, Christopher L. / Usyatinsky, Alexander / Fitzpatrick, Kevin / Masih, Liaqat / Guo, Cheng / Zhang, Zhenjun / Choo, Sok Hui / Sikkander, M. Inthikhab / Ryan, Kristen N. et al. | 2010
- 62
-
Rapid access to new bioconjugates of betulonic acid via click chemistryVasilevsky, Sergey F. / Govdi, Anastasiya I. / Sorokina, Irina V. / Tolstikova, Tatyana G. / Baev, Dmitry S. / Tolstikov, Genrikh A. / Mamatuyk, Victor I. / Alabugin, Igor V. et al. | 2010
- 66
-
Understanding DP receptor antagonism using a CoMSIA approachMu, Lan / Aguiar, Joacy / Ardati, Ali / Cao, Bin / Gardner, Charles J. / Gillespy, Tim / Harris, Keith / Lim, Sungtaek / Marcus, Robert / Morize, Isabelle et al. | 2010
- 76
-
Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole coreShen, Dong-Ming / Brady, Edward J. / Candelore, Mari R. / Dallas-Yang, Qing / Ding, Victor D.-H. / Feeney, William P. / Jiang, Guoquiang / McCann, Margaret E. / Mock, Steve / Qureshi, Sajjad A. et al. | 2010
- 82
-
Quinolones as HCV NS5B polymerase inhibitorsKumar, Dange V. / Rai, Roopa / Brameld, Ken A. / Somoza, John R. / Rajagopalan, Ravi / Janc, James W. / Xia, Yu M. / Ton, Tony L. / Shaghafi, Michael B. / Hu, Huiyong et al. | 2010
- 88
-
Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine releaseZhang, Zhenfa / Zheng, Guangrong / Pivavarchyk, Marharyta / Deaciuc, A. Gabriela / Dwoskin, Linda P. / Crooks, Peter A. et al. | 2010
- 92
-
The characterization of a novel V1b antagonist lead seriesSmethurst, Chris A. / Borthwick, Jennifer A. / Gaines, Simon / Watson, Steve / Green, Andrew / Schulz, Mark J. / Burton, George / Buson, Alberto A. / Arban, Roberto et al. | 2010
- 97
-
Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitorsRay, Peter / Wright, Jane / Adam, Julia / Bennett, Johnathan / Boucharens, Sylviane / Black, Darcey / Cook, Andrew / Brown, Angus R. / Epemolu, Ola / Fletcher, Dan et al. | 2010
- 102
-
Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamidesPacchiano, Fabio / Carta, Fabrizio / Vullo, Daniela / Scozzafava, Andrea / Supuran, Claudiu T. et al. | 2010
- 102
-
Inhibition of b-carbonic anhydrases with ureido-substituted benzenesulfonamidesPacchiano, F. / Carta, F. / Vullo, D. / Scozzafava, A. / Supuran, C. T. et al. | 2011
- 106
-
Inhibition of P-glycoprotein-mediated Multidrug Resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: Further restriction of molecular flexibility maintains high potency and efficacyMartelli, Cecilia / Dei, Silvia / Lambert, Catherine / Manetti, Dina / Orlandi, Francesca / Romanelli, Maria Novella / Scapecchi, Serena / Salerno, Milena / Teodori, Elisabetta et al. | 2010
- 110
-
Application of p21 and klf2 reporter gene assays to identify selective histone deacetylase inhibitors for cancer therapyWong, Jason C. / Guo, Lei / Peng, Zhenghong / Zhang, Weixing / Zhang, Nan / Lai, Wayne / Zhang, Zhenshan / Zhang, Chao / Zhang, Xiongwen / Song, Shan et al. | 2010
- 117
-
Diphenylpropynone derivatives as probes for imaging b-amyloid plaques in Alzheimer's brainsOno, M. / Watanabe, H. / Watanabe, R. / Haratake, M. / Nakayama, M. / Saji, H. et al. | 2011
- 117
-
Diphenylpropynone derivatives as probes for imaging β-amyloid plaques in Alzheimer’s brainsOno, Masahiro / Watanabe, Hiroyuki / Watanabe, Rumi / Haratake, Mamoru / Nakayama, Morio / Saji, Hideo et al. | 2010
- 121
-
Design of novel N-phenylnicotinamides as selective cyclooxygenase-1 inhibitorsShi, Lei / Li, Zi-Lin / Yang, Ying / Zhu, Zhen-Wei / Zhu, Hai-Liang et al. | 2010
- 125
-
Ring A-seco triterpenoids with antibacterial activity from Dysoxylum hainanenseHe, Xiu-Feng / Wang, Xiao-Ning / Yin, Sheng / Dong, Lei / Yue, Jian-Min et al. | 2010
- 130
-
Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agentsLi, Jing / Zhang, Dayong / Wu, Xiaoming et al. | 2010
- 133
-
Peptide deformylase inhibitors with non-peptide scaffold: Synthesis and structure–activity relationshipsLee, Seung Kyu / Choi, Kwang Hyun / Lee, Sang Jae / Lee, Jong Sun / Park, Ji Yun / Kim, B. Moon / Lee, Bong Jin et al. | 2010
- 137
-
Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonistBrown, Angus R. / Bosies, Michael / Cameron, Helen / Clark, John / Cowley, Angela / Craighead, Mark / Elmore, Moira A. / Firth, Alistair / Goodwin, Richard / Goutcher, Susan et al. | 2010
- 141
-
Correlation analyses on binding affinity of substituted benzenesulfonamides with carbonic anhydrase using ab initio MO calculations on their complex structures (II)Munei, Yohei / Shimamoto, Kazunori / Harada, Masataka / Yoshida, Tatsusada / Chuman, Hiroshi et al. | 2010
- 145
-
Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agentsDe Jonghe, Steven / Marchand, Arnaud / Gao, Ling-Jie / Calleja, Agnes / Cuveliers, Eva / Sienaert, Ilse / Herman, Jean / Clydesdale, Gavin / Sefrioui, Hassane / Lin, Yuan et al. | 2010
- 150
-
Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors—Analogues of SAD-128Musilek, Kamil / Roder, Jan / Komloova, Marketa / Holas, Ondrej / Hrabinova, Martina / Pohanka, Miroslav / Dohnal, Vlastimil / Opletalova, Veronika / Kuca, Kamil / Jung, Young-Sik et al. | 2010
- 155
-
RNA aptazyme-tethered large gold nanoparticles for on-the-spot sensing of the aptazyme ligandOgawa, Atsushi et al. | 2010
- 160
-
Synthesis and biological evaluation of new salvinorin A analogues incorporating natural amino acidsFichna, Jakub / Lewellyn, Kevin / Yan, Feng / Roth, Bryan L. / Zjawiony, Jordan K. et al. | 2010
- 164
-
Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitorsWeinberg, Linda R. / Albom, Mark S. / Angeles, Thelma S. / Husten, Jean / Lisko, Joseph G. / McHugh, Robert J. / Milkiewicz, Karen L. / Murthy, Seetha / Ott, Gregory R. / Theroff, Jay P. et al. | 2010
- 168
-
Tetrahydroquinoline glucocorticoid receptor agonists: Discovery of a 3-hydroxyl for improving receptor selectivityRoach, Steven L. / Higuchi, Robert I. / Hudson, Andrew R. / Adams, Mark E. / Syka, Peter M. / Mais, Dale E. / Miner, Jeffrey N. / Marschke, Keith B. / Zhi, Lin et al. | 2010
- 172
-
MDCK cell permeability characteristics of a sulfenamide prodrug: Strategic implications in considering sulfenamide prodrugs for oral delivery of NH-acidsGuarino, Victor R. / Nti-Addae, Kwame / Stella, Valentino J. et al. | 2010
- 176
-
Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraceptionKumar, Lalit / Sarswat, Amit / Lal, Nand / Jain, Ashish / Kumar, Sumit / Kiran Kumar, S.T.V.S. / Maikhuri, Jagdamba P. / Pandey, Atindra K. / Shukla, Praveen K. / Gupta, Gopal et al. | 2010
- 182
-
Structure–activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic painYang, Shu-Wei / Smotryski, Jennifer / Matasi, Julius / Ho, Ginny / Tulshian, Deen / Greenlee, William J. / Brusa, Rossella / Beltramo, Massimiliano / Cox, Kathleen et al. | 2010
- 186
-
N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2)Zimmer, Christina / Hafner, Marieke / Zender, Michael / Ammann, Dominic / Hartmann, Rolf W. / Vock, Carsten A. et al. | 2010
- 191
-
Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetesRichter, Hans G.F. / Benson, Gregory M. / Blum, Denise / Chaput, Evelyne / Feng, Song / Gardes, Christophe / Grether, Uwe / Hartman, Peter / Kuhn, Bernd / Martin, Rainer E. et al. | 2010
- 195
-
3-(Pyridin-2-yl-ethynyl)benzamide metabotropic glutamate receptor 5 negative allosteric modulators: Hit to lead studiesGilbert, Adam M. / Bursavich, Matthew G. / Lombardi, Sabrina / Adedoyin, Adedayo / Dwyer, Jason M. / Hughes, Zoe / Kern, Jeffrey C. / Khawaja, Xavier / Rosenzweig-Lipson, Sharon / Moore, William J. et al. | 2010
- 200
-
In vitro evaluation of 5-arylidene-2-thioxo-4-thiazolidinones active as aldose reductase inhibitorsMaccari, Rosanna / Corso, Antonella Del / Giglio, Marco / Moschini, Roberta / Mura, Umberto / Ottanà, Rosaria et al. | 2010
- 204
-
Structure of fomitellan A, a mannofucogalactan from the fruiting bodies of Fomitella fraxineaCho, Soo-Muk / Yun, Bong-Sik / Yoo, Ick-Dong / Koshino, Hiroyuki et al. | 2010
- 207
-
Inhibitory effects of hybrid liposomes on the growth of synoviocyte causing rheumatoid arthritisIchihara, Hideaki / Hino, Motoki / Makizono, Taku / Umebayashi, Masayo / Matsumoto, Yoko / Ueoka, Ryuichi et al. | 2010
- 211
-
Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivativesNa, Younghwa / Nam, Jung-Min et al. | 2010
- 215
-
Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockersChoi, Yeon-hee / Baek, Du Jong / Seo, Seon Hee / Lee, Jae Kyun / Pae, Ae Nim / Cho, Yong Seo / Min, Sun-Joon et al. | 2010
- 220
-
Development of a new class of benzoylpyrrole-based PPARa/g activatorsUshiroda, K. / Maruta, K. / Kitoh, M. / Iwai, K. / Nagamine, J. / Tsuchida, A. / Taiji, M. / Nagata, R. et al. | 2011
- 220
-
Development of a new class of benzoylpyrrole-based PPARα/γ activatorsUshiroda, Kantaro / Maruta, Katsunori / Kitoh, Makoto / Iwai, Kiyotaka / Nagamine, Jun / Tsuchida, Atsushi / Taiji, Mutsuo / Nagata, Ryu et al. | 2010
- 225
-
Antisense effect of pyrrolidine-based oxy-peptide nucleic acids in Escherichia coliKitamatsu, Mizuki / Kurami, Shunsuke / Ohtsuki, Takashi / Sisido, Masahiko et al. | 2010
- 228
-
Synthesis and antihyperglycemic activity of phenolic C-glycosidesRawat, Preeti / Kumar, Manmeet / Rahuja, Neha / Srivastava, Daya Shankar Lal / Srivastava, Arvind Kumar / Maurya, Rakesh et al. | 2010
- 234
-
Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducersChen, Gang / Xia, Hongguang / Cai, Yu / Ma, Dawei / Yuan, Junying / Yuan, Chengye et al. | 2010
- 240
-
Synthesis of a novel human PPARd selective agonist and its stimulatory effect on oligodendrocyte differentiationSakuma, S. / Endo, T. / Kanda, T. / Nakamura, H. / Yamasaki, S. / Yamakawa, T. et al. | 2011
- 240
-
Synthesis of a novel human PPARδ selective agonist and its stimulatory effect on oligodendrocyte differentiationSakuma, Shogo / Endo, Tsuyoshi / Kanda, Takashi / Nakamura, Hideki / Yamasaki, Satomi / Yamakawa, Tomio et al. | 2010
- 245
-
The first synthesis of [11C]SB-216763, a new potential PET agent for imaging of glycogen synthase kinase-3 (GSK-3)Wang, Min / Gao, Mingzhang / Miller, Kathy D. / Sledge, George W. / Hutchins, Gary D. / Zheng, Qi-Huang et al. | 2010
- 250
-
Molecular modeling and UV–vis spectroscopic studies on the mechanism of action of reversed chloroquine (RCQ)Otelo, Vanessa A. / Sant’Ana, Antonio C. / de Faria, Dalva L.A. / Menezes, Carla M.S. et al. | 2010
- 255
-
Control of lysyl oxidase activity through site-specific deuteration of lysinePestov, Nikolay B. / Okkelman, Irina A. / Shmanai, Vadim V. / Hurski, Alaksiej L. / Giaccia, Amato J. / Shchepinov, Mikhail S. et al. | 2010
- 259
-
A new and efficient synthetic route for the anxiolytic agent CL285032Ghidu, Victor P. / Ilies, Marc A. / Cullen, Tom / Pollet, Robert / Abou-Gharbia, Magid et al. | 2010
- 262
-
Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replicationSkerlj, Renato / Bridger, Gary / McEachern, Ernie / Harwig, Curtis / Smith, Chris / Wilson, Trevor / Veale, Duane / Yee, Helen / Crawford, Jason / Skupinska, Krystyna et al. | 2010
- 267
-
Pyrinodemins E and F, new 3-alkylpyridine alkaloids from sponge Amphimedon sp.Kura, Ken’ichi / Kubota, Takaaki / Fromont, Jane / Kobayashi, Jun’ichi et al. | 2010
- 271
-
The identification, and optimisation of hERG selectivity, of a mixed NET/SERT re-uptake inhibitor for the treatment of painAngus, Derek / Bingham, Matilda / Buchanan, Dawn / Dunbar, Neil / Gibson, Linsday / Goodwin, Richard / Haunsø, Anders / Houghton, Andrea / Huggett, Margaret / Morphy, Richard et al. | 2010
- 276
-
The discovery and structure–activity relationships leading to CE-156811, a difluorophenyl cyclopropyl fluoroether: A novel potent antibacterial analog derived from hygromycin ALe, Phuong T. / Brickner, Steven J. / Wade, Sarah K. / Brighty, Katherine / Monahan, Rhonda / Stone, Gregory G. / Girard, Dennis / Finegan, Steve / Duignan, Joan / Schafer, John et al. | 2010
- 280
-
Synthesis and spectroscopy of near infrared fluorescent dyes for investigating dichromic fluorescenceBai, Mingfeng / Achilefu, Samuel et al. | 2010
- 285
-
Oxidative inactivation of the lymphoid tyrosine phosphatase mediated by both general and active site directed NO donorsKarver, Caitlin E. / Ahmed, Vanessa F. / Barrios, Amy M. et al. | 2010
- 288
-
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseasesGallant, Michel / Beaulieu, Christian / Berthelette, Carl / Colucci, John / Crackower, Michael A. / Dalton, Chad / Denis, Danielle / Ducharme, Yves / Friesen, Richard W. / Guay, Daniel et al. | 2010
- 294
-
Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflataDao, Trong Tuan / Nguyen, Phi Hung / Lee, Hong Sik / Kim, Eunhee / Park, Junsoo / Lim, Seong Il / Oh, Won Keun et al. | 2010
- 299
-
Receptor activity and conformational analysis of 5′-halogenated resiniferatoxin analogs as TRPV1 ligandsLim, Kwang Su / Kang, Dong Wook / Kim, Yong Soo / Kim, Myeong Seop / Park, Seul-Gi / Choi, Sun / Pearce, Larry V. / Blumberg, Peter M. / Lee, Jeewoo et al. | 2010
- 299
-
Receptor activity and conformational analysis of 5prime-halogenated resiniferatoxin analogs as TRPV1 ligandsLim, K. S. / Kang, D. W. / Kim, Y. S. / Kim, M. S. / Park, S. G. / Choi, S. / Pearce, L. V. / Blumberg, P. M. / Lee, J. et al. | 2011
- 303
-
Signal turn-on probe for nucleic acid detection based on 19F nuclear magnetic resonanceSakamoto, Takashi / Shimizu, Yu-ki / Sasaki, Jun / Hayakawa, Hikaru / Fujimoto, Kenzo et al. | 2010
- 307
-
Structure–activity relationship (SAR) of the α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonistsZhong, Min / Hanan, Emily J. / Shen, Wang / Bui, Minna / Arkin, Michelle R. / Barr, Kenneth J. / Evanchik, Marc J. / Hoch, Ute / Hyde, Jennifer / Martell, Jose R. et al. | 2010
- 307
-
Structure-activity relationship (SAR) of the a-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonistsZhong, M. / Hanan, E. J. / Shen, W. / Bui, M. / Arkin, M. R. / Barr, K. J. / Evanchik, M. J. / Hoch, U. / Hyde, J. / Martell, J. R. et al. | 2011
- 311
-
Large scale enzymatic synthesis of oligosaccharides and a novel purification processZhou, Guangyan / Liu, Xianwei / Su, Doris / Li, Lei / Xiao, Min / Wang, Peng G. et al. | 2010
- 315
-
Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegenerationProbst, Gary D. / Bowers, Simeon / Sealy, Jennifer M. / Truong, Anh P. / Hom, Roy K. / Galemmo, Robert A. Jr. / Konradi, Andrei W. / Sham, Hing L. / Quincy, David A. / Pan, Hu et al. | 2010
- 320
-
Development of benzothiazole ‘click-on’ fluorogenic dyesQi, Jianjun / Tung, Ching-Hsuan et al. | 2010
- 324
-
Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitorsPabba, Chittari / Gregg, Brian T. / Kitchen, Douglas B. / Chen, Zhen Jia / Judkins, Angela et al. | 2010
- 329
-
A facile, click chemistry-based approach to assembling fluorescent chemosensors for protein tyrosine kinasesKamaruddin, Mohd Aizuddin / Ung, Phuc / Hossain, Mohammed Iqbal / Jarasrassamee, Boonyarin / O’Malley, William / Thompson, Philip / Scanlon, Denis / Cheng, Heung-Chin / Graham, Bim et al. | 2010
- 332
-
Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1Ouellet, Hugues / Kells, Petrea M. / Ortiz de Montellano, Paul R. / Podust, Larissa M. et al. | 2010
- 338
-
Efficient synthesis and biological evaluation of epiceanothic acid and related compoundsZhang, Pu / Xu, Li / Qian, Keduo / Liu, Jun / Zhang, Luyong / Lee, Kuo-Hsiung / Sun, Hongbin et al. | 2010
- 342
-
Asymmetric synthesis of phenanthroindolizidine alkaloids with hydroxyl group at the C14 position and evaluation of their antitumor activitiesIkeda, Takashi / Yaegashi, Takashi / Matsuzaki, Takeshi / Hashimoto, Syusuke / Sawada, Seigo et al. | 2010
- 346
-
Indole-3-piperazinyl derivatives: Novel chemical class of 5-HT6 receptor antagonistsNirogi, Ramakrishna V.S. / Deshpande, Amol D. / Kambhampati, Ramasastri / Badange, Rajesh Kumar / Kota, Laxman / Daulatabad, Anand V. / Shinde, Anil K. / Ahmad, Ishtiyaque / Kandikere, Vishwottam / Jayarajan, Pradeep et al. | 2010
- 350
-
An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activityKamal, Ahmed / Kumar, B. Ashwini / Suresh, Paidakula / Shankaraiah, Nagula / Kumar, M. Shiva et al. | 2010
- 350
-
An efficient one-pot synthesis of benzothiazolo-4b-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activityKamal, A. / Kumar, B. A. / Suresh, P. / Shankaraiah, N. / Kumar, M. S. et al. | 2011
- 354
-
Bitriazolyl acyclonucleosides synthesized via Huisgen reaction using internal alkynes show antiviral activity against tobacco mosaic virusWang, Menghua / Zhu, Ruizhi / Fan, Zhijin / Fu, Yifeng / Feng, Liang / Yao, Jianhua / Maggiani, Alain / Xia, Yi / Qu, Fanqi / Peng, Ling et al. | 2010
- 358
-
Design and synthesis of potent macrocyclic renin inhibitorsSund, Christian / Belda, Oscar / Wiktelius, Daniel / Sahlberg, Christer / Vrang, Lotta / Sedig, Susanne / Hamelink, Elizabeth / Henderson, Ian / Agback, Tatiana / Jansson, Katarina et al. | 2010
- 363
-
Silanetriols as in vitro inhibitors for AChEBlunder, Martina / Hurkes, Natascha / Spirk, Stefan / List, Martina / Pietschnig, Rudolf et al. | 2010
- 366
-
Antiproliferative and apoptotic sesquiterpene lactones from Carpesium faberiLi, Xu-Wen / Weng, Liang / Gao, Xue / Zhao, Yun / Pang, Fei / Liu, Jian-Hui / Zhang, Hong-Feng / Hu, Jin-Feng et al. | 2010
- 373
-
Two dimeric lignans with an unusual a,b-unsaturated ketone motif from Zanthoxylum podocarpum and their inhibitory effects on nitric oxide productionZhou, X. J. / Chen, X. L. / Li, X. S. / Su, J. / He, J. B. / Wang, Y. H. / Li, Y. / Cheng, Y. X. et al. | 2011
- 373
-
Two dimeric lignans with an unusual α,β-unsaturated ketone motif from Zanthoxylum podocarpum and their inhibitory effects on nitric oxide productionZhou, Xiao-Jiang / Chen, Xiao-Liang / Li, Xue-Song / Su, Jia / He, Jiang-Bo / Wang, Yue-Hu / Li, Yan / Cheng, Yong-Xian et al. | 2010
- 377
-
Potent transglutaminase inhibitors, dithio b-aminoethyl ketonesOzaki, S. / Ebisui, E. / Hamada, K. / Suzuki, A. Z. / Terauchi, A. / Mikoshiba, K. et al. | 2011
- 377
-
Potent transglutaminase inhibitors, dithio β-aminoethyl ketonesOzaki, Shoichiro / Ebisui, Etsuko / Hamada, Kozo / Suzuki, Akinobu Z. / Terauchi, Akiko / Mikoshiba, Katsuhiko et al. | 2010
- 380
-
Glycosylated nordihydroguaiaretic acids as anti-cancer agentsHwu, Jih Ru / Hsu, Chuan-I / Hsu, Ming-Hua / Liang, Yu-Chuan / Huang, Ru Chih C. / Lee, Yuan C. et al. | 2010
- 383
-
Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: Synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritisDyckman, Alaric J. / Langevine, Charles M. / Quesnelle, Claude / Kempson, James / Guo, Junqing / Gill, Patrice / Spergel, Steven H. / Watterson, Scott H. / Li, Tianle / Nirschl, David S. et al. | 2010
- 387
-
Modifications of the C6-substituent of penicillin sulfones with the goal of improving inhibitor recognition and efficacyNottingham, Micheal / Bethel, Christopher R. / Pagadala, Sundar Ram Reddy / Harry, Emily / Pinto, Abishai / Lemons, Zachary A. / Drawz, Sarah M. / Akker, Focco van den / Carey, Paul R. / Bonomo, Robert A. et al. | 2010
- 394
-
Synthesis and biological characterisation of novel dithiocarbamate containing 5-nitroimidazole 99mTc-complexes as potential agents for targeting hypoxiaGiglio, Javier / Fernández, Soledad / Rey, Ana / Cerecetto, Hugo et al. | 2010
- 398
-
Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assemblyFader, Lee D. / Bethell, Richard / Bonneau, Pierre / Bös, Michael / Bousquet, Yves / Cordingley, Michael G. / Coulombe, René / Deroy, Patrick / Faucher, Anne-Marie / Gagnon, Alexandre et al. | 2010
- 405
-
Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11b-HSD1 inhibitorsSun, D. / Wang, Z. / Caille, S. / DeGraffenreid, M. / Gonzalez-Lopez de Turiso, F. / Hungate, R. / Jaen, J. C. / Jiang, B. / Julian, L. D. / Kelly, R. et al. | 2011
- 405
-
Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitorsSun, Daqing / Wang, Zhulun / Caille, Seb / DeGraffenreid, Michael / Gonzalez-Lopez de Turiso, Felix / Hungate, Randall / Jaen, Juan C. / Jiang, Ben / Julian, Lisa D. / Kelly, Ron et al. | 2010
- 411
-
Synthesis and biological activity of pyridopyridazin-6-one p38 MAP kinase inhibitors. Part 1Tynebor, Robert M. / Chen, Meng-Hsin / Natarajan, Swaminathan R. / O’Neill, Edward A. / Thompson, James E. / Fitzgerald, Catherine E. / O’Keefe, Stephen J. / Doherty, James B. et al. | 2010
- 417
-
A novel series of IKKβ inhibitors part I: Initial SAR studies of a HTS hitCushing, Timothy D. / Baichwal, Vijay / Berry, Karen / Billedeau, Roland / Bordunov, Viola / Broka, Chris / Cardozo, Mario / Cheng, Peng / Clark, David / Dalrymple, Stacie et al. | 2010
- 417
-
A novel series of IKKb inhibitors part I: Initial SAR studies of a HTS hitCushing, T. D. / Baichwal, V. / Berry, K. / Billedeau, R. / Bordunov, V. / Broka, C. / Cardozo, M. / Cheng, P. / Clark, D. / Dalrymple, S. et al. | 2011
- 423
-
A novel series of IKKβ inhibitors part II: Description of a potent and pharmacologically active series of analogsCushing, Timothy D. / Baichwal, Vijay / Berry, Karen / Billedeau, Roland / Bordunov, Viola / Broka, Chris / Browner, Michelle F. / Cardozo, Mario / Cheng, Peng / Clark, David et al. | 2010
- 423
-
A novel series of IKKb inhibitors part II: Description of a potent and pharmacologically active series of analogsCushing, T. D. / Baichwal, V. / Berry, K. / Billedeau, R. / Bordunov, V. / Broka, C. / Browner, M. F. / Cardozo, M. / Cheng, P. / Clark, D. et al. | 2011
- 427
-
Synthesis and antifungal evaluation of 6-hydroxy-1H-carbazole-1,4(9H)-dionesRyu, Chung-Kyu / Lee, Seung-Yon / Kim, Na Young / Hong, Jung An / Yoon, Joo Hee / Kim, Aram et al. | 2010
- 431
-
Synthesis and biological evaluation of tubulysin D analogs related to stereoisomers of tubuvalineShibue, Taku / Okamoto, Iwao / Morita, Nobuyoshi / Morita, Hiroshi / Hirasawa, Yusuke / Hosoya, Takahiro / Tamura, Osamu et al. | 2010
- 435
-
Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl groupKwon, Sung Wook / Kang, Seung Kyu / Lee, Jae Hong / Bok, Joo Hwan / Kim, Chi Hyun / Rhee, Sang Dal / Jung, Won Hoon / Kim, Hee Youn / Bae, Myung Ae / Song, Jin Sook et al. | 2010
- 435
-
Synthesis and 11b hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl groupKwon, S. W. / Kang, S. K. / Lee, J. H. / Bok, J. H. / Kim, C. H. / Rhee, S. D. / Jung, W. H. / Kim, H. Y. / Bae, M. A. / Song, J. S. et al. | 2011
- 440
-
Novel gratisin derivatives with high antimicrobial activity and low hemolytic activityTamaki, Makoto / Imazeki, Yukie / Shirane, Aya / Fujinuma, Kenta / Shindo, Mitsuno / Kimura, Masahiro / Uchida, Yoshiki et al. | 2010
- 444
-
Microwave assisted one pot synthesis of some novel 2,5-disubstituted 1,3,4-oxadiazoles as antifungal agentsSangshetti, Jaiprakash N. / Chabukswar, Aniruddha R. / Shinde, Devanand B. et al. | 2010
- 449
-
Click chemistry inspired one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their Src kinase inhibitory activityKumar, Dalip / Reddy, V. Buchi / Kumar, Anil / Mandal, Deendayal / Tiwari, Rakesh / Parang, Keykavous et al. | 2010
- 453
-
Design and efficient synthesis of A-278637 derivatives as potential potassium channel openerLi, Tuanjie / Feng, Xiaodong / Yao, Changsheng / Yu, Chenxia / Jiang, Bei / Tu, Shujiang et al. | 2010
- 456
-
CoMFA and CoMSIA studies on 5-hydroxyindole-3-carboxylate derivatives as 5-lipoxygenase inhibitors: Generation of homology model and docking studiesAparoy, P. / Suresh, G.K. / Kumar Reddy, K. / Reddanna, P. et al. | 2010
- 463
-
Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse modelsMesaros, Eugen F. / Burke, Jason P. / Parrish, Jonathan D. / Dugan, Benjamin J. / Anzalone, Andrew V. / Angeles, Thelma S. / Albom, Mark S. / Aimone, Lisa D. / Quail, Matthew R. / Wan, Weihua et al. | 2010
- 467
-
Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 1Dwyer, Michael P. / Paruch, Kamil / Labroli, Marc / Alvarez, Carmen / Keertikar, Kerry M. / Poker, Cory / Rossman, Randall / Fischmann, Thierry O. / Duca, Jose S. / Madison, Vincent et al. | 2010
- 471
-
Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 2Labroli, Marc / Paruch, Kamil / Dwyer, Michael P. / Alvarez, Carmen / Keertikar, Kartik / Poker, Cory / Rossman, Randall / Duca, Jose S. / Fischmann, Thierry O. / Madison, Vincent et al. | 2010
- 475
-
Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitorYao, Zhiyi / Xu, Yingjun / Zhang, Minmin / Jiang, Sheng / Nicklaus, Marc C. / Liao, Chenzhong et al. | 2010
- 475
-
Discovery of a novel hybrid from finasteride and epristeride as 5a-reductase inhibitorYao, Z. / Xu, Y. / Zhang, M. / Jiang, S. / Nicklaus, M. C. / Liao, C. et al. | 2011
- 479
-
Biological activity and preclinical efficacy of azetidinyl pyridazines as potent systemically-distributed stearoyl-CoA desaturase inhibitorsIsabel, Elise / Powell, David A. / Black, W. Cameron / Chan, Chi-Chung / Crane, Sheldon / Gordon, Robert / Guay, Jocelyne / Guiral, Sebastien / Huang, Zheng / Robichaud, Joël et al. | 2010
- 484
-
A novel series of potent and selective EP4 receptor ligands: Facile modulation of agonism and antagonismBoyd, Michael J. / Berthelette, Carl / Chiasson, Jean-François / Clark, Patsy / Colucci, John / Denis, Danielle / Han, Yongxin / Lévesque, Jean-Francois / Mathieu, Marie-Claude / Stocco, Rino et al. | 2010
- 488
-
Chromanol derivatives—A novel class of CETP inhibitorsVakalopoulos, Alexandros / Schmeck, Carsten / Thutewohl, Michael / Li, Volkhart / Bischoff, Hilmar / Lustig, Klemens / Weber, Olaf / Paulsen, Holger / Elias, Harry et al. | 2010
- 492
-
Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPARδ agonistsLuckhurst, Christopher A. / Stein, Linda A. / Furber, Mark / Webb, Nicola / Ratcliffe, Marianne J. / Allenby, Gary / Botterell, Sara / Tomlinson, Wendy / Martin, Barrie / Walding, Andrew et al. | 2010
- 492
-
Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPARd agonistsLuckhurst, C. A. / Stein, L. A. / Furber, M. / Webb, N. / Ratcliffe, M. J. / Allenby, G. / Botterell, S. / Tomlinson, W. / Martin, B. / Walding, A. et al. | 2011
- 497
-
The discovery of novel indole-2-carboxamides as cannabinoid CB1 receptor antagonistsCowley, Phillip M. / Baker, James / Barn, David R. / Buchanan, Kirsteen I. / Carlyle, Ian / Clark, John K. / Clarkson, Thomas R. / Deehan, Maureen / Edwards, Darren / Goodwin, Richard R. et al. | 2010
- 502
-
Radiolabeling and preliminary biological evaluation of a 99mTc(CO)3 labeled 3,3′-(benzylidene)-bis-(1H-indole-2-carbohydrazide) derivative as a potential SPECT tracer for in vivo visualization of necrosisPrinsen, Kristof / Jin, Lixin / Vunckx, Kathleen / De Saint-Hubert, Marijke / Zhou, Lin / Cleynhens, Jan / Nuyts, Johan / Bormans, Guy / Ni, Yicheng / Verbruggen, Alfons et al. | 2010
- 502
-
Radiolabeling and preliminary biological evaluation of a 99mTc(CO)3 labeled 3,3prime-(benzylidene)-bis-(1H-indole-2-carbohydrazide) derivative as a potential SPECT tracer for in vivo visualization of necrosisPrinsen, K. / Jin, L. / Vunckx, K. / De Saint-Hubert, M. / Zhou, L. / Cleynhens, J. / Nuyts, J. / Bormans, G. / Ni, Y. / Verbruggen, A. et al. | 2011
- 506
-
Design, synthesis, and structure–activity relationships of indole-3-heterocycles as agonists of the CB1 receptorMorrison, Angus J. / Adam, Julia M. / Baker, James A. / Campbell, Robert A. / Clark, John K. / Cottney, Jean E. / Deehan, Maureen / Easson, Anna-Marie / Fields, Ruth / Francis, Stuart et al. | 2010
- 510
-
Synthesis and antibacterial activity of novel 4-aryl-[1,2,3]-triazole containing macrolidesPereira, David / Fernandes, Prabhavathi et al. | 2010
- 514
-
Reactions of nitroxides. Part X: Antifungal activity of selected sulfur and selenium derivatives of 2,2,6,6-tetramethylpiperidineZakrzewski, Jerzy / Krawczyk, Maria et al. | 2010
- 517
-
Evaluation of hadacidin analoguesTibrewal, Nidhi / Elliott, Gregory I. et al. | 2010
- 520
-
Discovery of 1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydroquinolin-4-amine, a dual serotonin and dopamine reuptake inhibitorShao, Liming / Ma, Jianguo / Wang, Fengjiang / Malcolm, Scott C. / Hewitt, Michael C. / Campbell, Una C. / Spicer, Nancy A. / Hardy, Larry W. / Schreiber, Rudy / Spear, Kerry L. et al. | 2010
- 524
-
3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agentsKuarm, B. Suresh / Reddy, Y. Thirupathi / Madhav, J. Venu / Crooks, Peter A. / Rajitha, B. et al. | 2010
- 528
-
Thiophene and bioisostere derivatives as new MMP12 inhibitorsBadland, Matthew / Compère, Delphine / Courté, Karine / Dublanchet, Anne-Claude / Blais, Stéphane / Manage, Ajith / Peron, Guillaume / Wrigglesworth, Roger et al. | 2010
- 531
-
Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARd agonistsLuckhurst, C. A. / Ratcliffe, M. / Stein, L. / Furber, M. / Botterell, S. / Laughton, D. / Tomlinson, W. / Weaver, R. / Chohan, K. / Walding, A. et al. | 2011
- 531
-
Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonistsLuckhurst, Christopher A. / Ratcliffe, Marianne / Stein, Linda / Furber, Mark / Botterell, Sara / Laughton, David / Tomlinson, Wendy / Weaver, Richard / Chohan, Kamaldeep / Walding, Andrew et al. | 2010
- 537
-
Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1Marcin, Lawrence R. / Higgins, Mendi A. / Zusi, F. Christopher / Zhang, Yunhui / Dee, Michael F. / Parker, Michael F. / Muckelbauer, Jodi K. / Camac, Daniel M. / Morin, Paul E. / Ramamurthy, Vidhyashankar et al. | 2010
- 542
-
Triterpene derivatives that inhibit human immunodeficiency virus type 1 replicationDorr, Casey R. / Yemets, Sergiy / Kolomitsyna, Oksana / Krasutsky, Pavel / Mansky, Louis M. et al. | 2010
- 546
-
Antitumor agents 281. Design, synthesis, and biological activity of substituted 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogs (ATBO) as potent in vitro anticancer agentsDong, Yizhou / Nakagawa-Goto, Kyoko / Lai, Chin-Yu / Morris-Natschke, Susan L. / Bastow, Kenneth F. / Lee, Kuo-Hsiung et al. | 2010
- 550
-
Protein kinase affinity reagents based on a 5-aminoindazole scaffoldKrishnamurty, Ratika / Brock, Amanda M. / Maly, Dustin J. et al. | 2010
- 555
-
Chalcone-based inhibitors against hypoxia-inducible factor 1—Structure activity relationship studiesSrinivasan, Balasubramanian / Johnson, Thomas E. / Xing, Chengguo et al. | 2010
- 558
-
2-Arylbenzoxazoles as CETP inhibitors: Raising HDL-C in cynoCETP transgenic miceKallashi, Florida / Kim, Dooseop / Kowalchick, Jennifer / Park, You Jung / Hunt, Julianne A. / Ali, Amjad / Smith, Cameron J. / Hammond, Milton L. / Pivnichny, James V. / Tong, Xinchun et al. | 2010
- 562
-
Novel pyrazole-3-carboxamide derivatives as cannabinoid-1 (CB1) antagonists: Journey from non-polar to polar amidesSasmal, Pradip K. / Reddy, D. Srinivasa / Talwar, Rashmi / Venkatesham, B. / Balasubrahmanyam, D. / Kannan, M. / Srinivas, P. / Kumar, K. Shiva / Devi, B. Neelima / Jadhav, Vikram P. et al. | 2010
- 569
-
Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: A new class of biological compoundsDubey, Adesh / Srivastava, S.K. / Srivastava, S.D. et al. | 2010
- 574
-
Synthesis and biological activity of novel 5′-arylamino-nucleosides by microwave-assisted one-pot tandem Staudinger/aza-Wittig/reductionChen, Hua / Zhao, Jianpeng / Li, Yanan / Shen, Fengjuan / Li, Xiaoliu / Yin, Qingmei / Qin, Zhanbin / Yan, Xinhao / Wang, Yanfei / Zhang, Pingzhu et al. | 2010
- 574
-
Synthesis and biological activity of novel 5prime-arylamino-nucleosides by microwave-assisted one-pot tandem Staudinger/aza-Wittig/reductionChen, H. / Zhao, J. / Li, Y. / Shen, F. / Li, X. / Yin, Q. / Qin, Z. / Yan, X. / Wang, Y. / Zhang, P. et al. | 2011
- 577
-
Discovery of a novel IKK-b inhibitor by ligand-based virtual screening techniquesNoha, S. M. / Atanasov, A. G. / Schuster, D. / Markt, P. / Fakhrudin, N. / Heiss, E. H. / Schrammel, O. / Rollinger, J. M. / Stuppner, H. / Dirsch, V. M. et al. | 2011
- 577
-
Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniquesNoha, Stefan M. / Atanasov, Atanas G. / Schuster, Daniela / Markt, Patrick / Fakhrudin, Nanang / Heiss, Elke H. / Schrammel, Olivia / Rollinger, Judith M. / Stuppner, Hermann / Dirsch, Verena M. et al. | 2010
- 584
-
Identification of novel pyrrolopyrazoles as protein kinase C b II inhibitorsLi, H. / Hong, Y. / Nukui, S. / Lou, J. / Johnson, S. / Scales, S. / Botrous, I. / Tompkins, E. / Yin, C. / Zhou, R. et al. | 2011
- 584
-
Identification of novel pyrrolopyrazoles as protein kinase C β II inhibitorsLi, Hui / Hong, Yufeng / Nukui, Seiji / Lou, Jihong / Johnson, Sarah / Scales, Stephanie / Botrous, Iriny / Tompkins, Eileen / Yin, Chunfeng / Zhou, Ru et al. | 2010
- 588
-
Replacing the 2′-oxygen with an exocyclic methylene group reverses the stabilization effects of α-l-LNASeth, Punit P. / Allerson, Charles R. / Berdeja, Andres / Swayze, Eric E. et al. | 2010
- 588
-
Replacing the 2prime-oxygen with an exocyclic methylene group reverses the stabilization effects of a-l-LNASeth, P. P. / Allerson, C. R. / Berdeja, A. / Swayze, E. E. et al. | 2011
- 592
-
Bioisosteric approach to the discovery of imidazo[1,2-a]pyrazines as potent Aurora kinase inhibitorsMeng, Zhaoyang / Kulkarni, Bheemashankar A. / Kerekes, Angela D. / Mandal, Amit K. / Esposite, Sara J. / Belanger, David B. / Reddy, Panduranga Adulla / Basso, Andrea D. / Tevar, Seema / Gray, Kimberly et al. | 2010
- 599
-
Design and an efficient synthesis of natural product-based cyclopenta[b]pyran derivatives with potential bioactivityYao, Changsheng / Jiang, Bei / Li, Tuanjie / Qin, Bingbin / Feng, Xiaodong / Zhang, Honghong / Wang, Cuihua / Tu, Shujiang et al. | 2010
- 602
-
Stereospecific synthesis and structure–activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitorsPizzi, Domenica A. / Leslie, Colin P. / Fabio, Romano Di / Seri, Catia / Bernasconi, Giovanni / Squaglia, Michela / Carnevale, Gennaro / Falchi, Alessandro / Greco, Elisabetta / Mangiarini, Laura et al. | 2010
- 606
-
Corrigendum to “A newly synthesized, potent tyrosinase inhibitor: 5-(6-Hydroxy-2-naphthyl)-1,2,3-benzenetriol” [Bioorg. Med. Chem. Lett. 20 (2010) 4882–4884]Choi, Jehun / Bae, Sung Jin / Ha, Young Mi / No, Jae Kyung / Lee, Eun Kyeong / Lee, Jun Sik / Song, Suhee / Lee, Hyojin / Suh, Hongsuk / Yu, Byung Pal et al. | 2010
- IFC
-
Editorial board| 2010