Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) Inhibitors (English)
- New search for: He, Yuanjun
- New search for: He, Yuanjun
- New search for: Kamenecka, Theodore M.
- New search for: Shin, Youseung
- New search for: Song, Xinyi
- New search for: Jiang, Rong
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- New search for: Duckett, Derek
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- New search for: Ling, Yuan Yuan
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In:
Bioorganic & medicinal chemistry letters
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21
, 6
; 1719-1724
;
2011
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ISSN:
- Article (Journal) / Print
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Title:Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) Inhibitors
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Contributors:He, Yuanjun ( author ) / Kamenecka, Theodore M. / Shin, Youseung / Song, Xinyi / Jiang, Rong / Noel, Romain / Duckett, Derek / Chen, Weimin / Ling, Yuan Yuan / Cameron, Michael D.
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Published in:Bioorganic & medicinal chemistry letters ; 21, 6 ; 1719-1724
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Publisher:
- New search for: Elsevier
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Place of publication:Amsterdam [u.a.]
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Publication date:2011
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ISSN:
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ZDBID:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 35.70 / 44.33 / 44.42
- Further information on Basic classification
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Keywords:
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Source:
Table of contents – Volume 21, Issue 6
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1559
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Graphical contents list| 2011
- 1578
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Application of plant allylpolyalkoxybenzenes in synthesis of antimitotic phenstatin analoguesTitov, Ilia Y. / Sagamanova, Irina K. / Gritsenko, Roman T. / Karmanova, Irina B. / Atamanenko, Olga P. / Semenova, Marina N. / Semenov, Victor V. et al. | 2011
- 1582
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Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifsYoung, Robert J. / Adams, Carl / Blows, Mike / Brown, David / Burns-Kurtis, Cynthia L. / Chan, Chuen / Chaudry, Laiq / Convery, Máire A. / Davies, David E. / Exall, Anne M. et al. | 2011
- 1588
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The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifsWatson, Nigel S. / Adams, Carl / Belton, David / Brown, David / Burns-Kurtis, Cynthia L. / Chaudry, Laiq / Chan, Chuen / Convery, Máire A. / Davies, David E. / Exall, Anne M. et al. | 2011
- 1593
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Synthesis and biological evaluation of 2,4-diaminoquinazoline derivatives as novel heat shock protein 90 inhibitorsThorat, Dhanaji Achyutrao / Doddareddy, Munikumar Reddy / Seo, Seon Hee / Hong, Tae-Joon / Cho, Yong Seo / Hahn, Ji-Sook / Pae, Ae Nim et al. | 2011
- 1598
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A photoreactive probe that differentiates the binding sites of noncompetitive GABA receptor antagonistsShimotahira, Hiroshi / Fusazaki, Sayaka / Ikeda, Izumi / Ozoe, Yoshihisa et al. | 2011
- 1601
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Synthesis and evaluation of novel pyrimidine-based dual EGFR/Her-2 inhibitorsSuzuki, Naoyuki / Shiota, Takeshi / Watanabe, Fumihiko / Haga, Norihiro / Murashi, Takami / Ohara, Takafumi / Matsuo, Kenji / Oomori, Naoki / Yari, Hiroshi / Dohi, Keiji et al. | 2011
- 1607
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Computational study of bindings of HL9, a nonapeptide fragment of human lysozyme, to HIV-1 fusion protein gp41Hartono, Yossa Dwi / Lee, Angelina Noviani / Lee-Huang, Sylvia / Zhang, Dawei et al. | 2011
- 1612
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Synthesis, biological evaluation and molecular docking studies of stellatin derivatives as cyclooxygenase (COX-1, COX-2) inhibitors and anti-inflammatory agentsGautam, Raju / Jachak, Sanjay M. / Kumar, Vivek / Mohan, C. Gopi et al. | 2011
- 1617
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Discovery of new inhibitor for PDE3 by virtual screeningKim, Ki Young / Lee, Hyuk / Yoo, Sung-Eun / Kim, Seong Hwan / Kang, Nam Sook et al. | 2011
- 1621
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N-Benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitorsAtkinson, Karen A. / Beretta, Elena E. / Brown, Janice A. / Castrodad, Mayda / Chen, Yue / Cosgrove, Judith M. / Du, Ping / Litchfield, John / Makowski, Michael / Martin, Kelly et al. | 2011
- 1626
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Isatin 1,2,3-triazoles as potent inhibitors against caspase-3Jiang, Yang / Hansen, Trond Vidar et al. | 2011
- 1630
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Novel second generation analogs of eribulin. Part I: Compounds containing a lipophilic C32 side chain overcome P-glycoprotein susceptibilityNarayan, Sridhar / Carlson, Eric M. / Cheng, Hongsheng / Du, Hong / Hu, Yongbo / Jiang, Yimin / Lewis, Bryan M. / Seletsky, Boris M. / Tendyke, Karen / Zhang, Huiming et al. | 2011
- 1634
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Novel second generation analogs of eribulin. Part II: Orally available and active against resistant tumors in vivoNarayan, Sridhar / Carlson, Eric M. / Cheng, Hongsheng / Condon, Krista / Du, Hong / Eckley, Sean / Hu, Yongbo / Jiang, Yimin / Kumar, Vipul / Lewis, Bryan M. et al. | 2011
- 1639
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Novel second generation analogs of eribulin. Part III: Blood–brain barrier permeability and in vivo activity in a brain tumor modelNarayan, Sridhar / Carlson, Eric M. / Cheng, Hongsheng / Condon, Krista / Du, Hong / Eckley, Sean / Hu, Yongbo / Jiang, Yimin / Kumar, Vipul / Lewis, Bryan M. et al. | 2011
- 1644
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Antiviral agents 3. Discovery of a novel small molecule non-nucleoside inhibitor of Hepatitis B Virus (HBV)Crosby, Ian T. / Bourke, David G. / Jones, Eric D. / Jeynes, Tyrone P. / Cox, Susan / Coates, Jonathan A.V. / Robertson, Alan D. et al. | 2011
- 1649
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[11C]Enzastaurin, the first design and radiosynthesis of a new potential PET agent for imaging of protein kinase CWang, Min / Xu, Lu / Gao, Mingzhang / Miller, Kathy D. / Sledge, George W. / Zheng, Qi-Huang et al. | 2011
- 1654
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Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced PEPCK activationHudson, Andrew R. / Higuchi, Robert I. / Roach, Steven L. / Valdez, Lino J. / Adams, Mark E. / Vassar, Angie / Rungta, Deepa / Syka, Peter M. / Mais, Dale E. / Marschke, Keith B. et al. | 2011
- 1658
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Tetrahydroquinolin-3-yl carbamate glucocorticoid receptor agonists with reduced PEPCK activationRoach, Steven L. / Higuchi, Robert I. / Hudson, Andrew R. / Vassar, Angie / Grant, Virginia H.S. / Lamer, Ryan / Hooper, Charlene / Rungta, Deepa / Syka, Peter M. / Mais, Dale E. et al. | 2011
- 1663
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Synthesis and photophysical properties of new SNARF derivatives as dual emission pH sensorsNakata, Eiji / Nazumi, Yoshijiro / Yukimachi, Yoshihiro / Uto, Yoshihiro / Maezawa, Hiroshi / Hashimoto, Toshihiro / Okamoto, Yasuko / Hori, Hitoshi et al. | 2011
- 1667
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Efficient synthesis of triazole moiety-containing nucleotide analogs and their inhibitory effects on a malic enzymeHou, Shuhua / Liu, Wujun / Ji, Debin / Zhao, Zongbao (Kent) et al. | 2011
- 1670
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SAR studies on dihydropyrimidinone antibioticsXu, Lianhong / Zhang, Lijun / Jones, Robert / Bryant, Clifford / Boddeker, Nina / Mabery, Eric / Bahador, Gina / Watson, Julia / Clough, Jeffery / Arimilli, Murty et al. | 2011
- 1675
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Synthesis and in vitro anti-HSV-1 activity of a novel Hsp90 inhibitor BJ-B11Ju, Huai-Qiang / Xiang, Yang-Fei / Xin, Bao-Juan / Pei, Ying / Lu, Jia-Xin / Wang, Qiao-Li / Xia, Min / Qian, Chui-Wen / Ren, Zhe / Wang, Sha-Yan et al. | 2011
- 1678
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Biotin tethered homotryptamine derivatives: High affinity probes of the human serotonin transporter (hSERT)Tomlinson, Ian D. / Iwamoto, Hideki / Blakely, Randy D. / Rosenthal, Sandra J. et al. | 2011
- 1683
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Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybridsLombard, Marli C. / N’Da, David D. / Breytenbach, Jaco C. / Smith, Peter J. / Lategan, Carmen A. et al. | 2011
- 1687
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Novel potent pyrimido[4,5-c]quinoline inhibitors of protein kinase CK2: SAR and preliminary assessment of their analgesic and anti-viral propertiesPierre, Fabrice / O’Brien, Sean E. / Haddach, Mustapha / Bourbon, Pauline / Schwaebe, Michael K. / Stefan, Eric / Darjania, Levan / Stansfield, Ryan / Ho, Caroline / Siddiqui-Jain, Adam et al. | 2011
- 1692
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Pyridyl amides as potent inhibitors of T-type calcium channelsReger, Thomas S. / Yang, Zhi-Qiang / Schlegel, Kelly-Ann S. / Shu, Youheng / Mattern, Christa / Cube, Rowena / Rittle, Kenneth E. / McGaughey, Georgia B. / Hartman, George D. / Tang, Cuyue et al. | 2011
- 1697
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Discovery of orally available tetrahydroquinoline-based glucocorticoid receptor agonistsHudson, Andrew R. / Higuchi, Robert I. / Roach, Steven L. / Adams, Mark E. / Vassar, Angela / Syka, Peter M. / Mais, Dale E. / Miner, Jeffrey N. / Marschke, Keith B. / Zhi, Lin et al. | 2011
- 1701
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Overcoming biochemical pharmacologic mechanisms of platinum resistance with a texaphyrin–platinum conjugateArambula, Jonathan F. / Sessler, Jonathan L. / Siddik, Zahid H. et al. | 2011
- 1706
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One step synthesis of 2-hydroxymethylisoflavone and their osteogenic activityKumar, Manmeet / Rawat, Preeti / Kureel, Jyoti / Singh, Anuj Kumar / Singh, Divya / Maurya, Rakesh et al. | 2011
- 1710
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Quinolizidinone carboxylic acid selective M1 allosteric modulators: SAR in the piperidine seriesKuduk, Scott D. / Chang, Ronald K. / Di Marco, Christina N. / Ray, William J. / Ma, Lei / Wittmann, Marion / Seager, Matthew A. / Koeplinger, Kenneth A. / Thompson, Charles D. / Hartman, George D. et al. | 2011
- 1716
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Phellinstatin, a new inhibitor of enoyl-ACP reductase produced by the medicinal fungus Phellinus linteusCho, Jun-Young / Kwon, Yun-Ju / Sohn, Mi-Jin / Seok, Soon-Ja / Kim, Won-Gon et al. | 2011
- 1719
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Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) InhibitorsHe, Yuanjun / Kamenecka, Theodore M. / Shin, Youseung / Song, Xinyi / Jiang, Rong / Noel, Romain / Duckett, Derek / Chen, Weimin / Ling, Yuan Yuan / Cameron, Michael D. et al. | 2011
- 1724
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Oxindole derivatives as inhibitors of TAK1 kinaseLockman, Jeffrey W. / Reeder, Matthew D. / Robinson, Rosann / Ormonde, Patricia A. / Cimbora, Daniel M. / Williams, Brandi L. / Willardsen, J. Adam et al. | 2011
- 1728
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Antibacterial activities of imidazolium, pyrrolidinium and piperidinium saltsIwai, Noritaka / Nakayama, Kyosuke / Kitazume, Tomoya et al. | 2011
- 1731
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Discovery of potent dipeptidyl peptidase IV inhibitors derived from β-aminoamides bearing substituted [1,2,3]-triazolopiperidines for the treatment of type 2 diabetesShan, Zhenwei / Peng, Min / Fan, Houxing / Lu, Qingtao / Lu, Peng / Zhao, Chuansheng / Chen, Yilang et al. | 2011
- 1731
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Discovery of potent dipeptidyl peptidase IV inhibitors derived from b-aminoamides bearing substituted [1,2,3]-triazolopiperidines for the treatment of type 2 diabetesShan, Z. / Peng, M. / Fan, H. / Lu, Q. / Lu, P. / Zhao, C. / Chen, Y. et al. | 2011
- 1736
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Discovery of novel mGluR1 antagonists: A multistep virtual screening approach based on an SVM model and a pharmacophore hypothesis significantly increases the hit rate and enrichment factorLi, Guo-Bo / Yang, Ling-Ling / Feng, Shan / Zhou, Jian-Ping / Huang, Qi / Xie, Huan-Zhang / Li, Lin-Li / Yang, Sheng-Yong et al. | 2011
- 1741
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Discovery of a potent, orally bioavailable pyrimidine VLA-4 antagonist effective in a sheep asthma modelSemko, Christopher M. / Chen, Linda / Dressen, Darren B. / Dreyer, Mark L. / Dunn, Whitney / Farouz, Francine S. / Freedman, Stephen B. / Holsztynska, Elizabeth J. / Jefferies, Michael / Konradi, Andrei W. et al. | 2011
- 1744
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Design and synthesis of tricyclic tetrahydroquinolines as a new series of nonsteroidal selective androgen receptor modulators (SARMs)Nagata, Naoya / Miyakawa, Motonori / Amano, Seiji / Furuya, Kazuyuki / Yamamoto, Noriko / Inoguchi, Kiyoshi et al. | 2011
- 1748
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Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonistsKiyoi, Takao / Adam, Julia M. / Clark, John K. / Davies, Keneth / Easson, Anna-Marie / Edwards, Darren / Feilden, Helen / Fields, Ruth / Francis, Stuart / Jeremiah, Fiona et al. | 2011
- 1754
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Lead detoxification activities and ADMET hepatotoxicities of a class of novel 5-(1-carbonyl-l-amino-acid)-2,2-dimethyl-[1,3]dithiolane-4-carboxylic acidsXu, Yanxia / Wang, Yuji / Zhao, Ming / Hou, Baoguang / Peng, Li / Zheng, Meiqing / Wu, Jianhui / Peng, Shiqi et al. | 2011
- 1758
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Novel dihydrothieno[2,3-e]indazole derivatives as IκB kinase inhibitorsTakahashi, Hiroyasu / Shinoyama, Mariko / Komine, Takashi / Nagao, Muneki / Suzuki, Masashi / Tsuchida, Hisatoshi / Katsuyama, Koichi et al. | 2011
- 1758
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Novel dihydrothieno[2,3-e]indazole derivatives as IkB kinase inhibitorsTakahashi, H. / Shinoyama, M. / Komine, T. / Nagao, M. / Suzuki, M. / Tsuchida, H. / Katsuyama, K. et al. | 2011
- 1763
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Design, synthesis and in vitro cytotoxicity of novel dinuclear platinum(II) complexesGao, Chuanzhu / Gou, Shaohua / Fang, Lei / Zhao, Jian et al. | 2011
- 1767
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Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799Ohwada, Jun / Ebiike, Hirosato / Kawada, Hatsuo / Tsukazaki, Masao / Nakamura, Mitsuaki / Miyazaki, Takuya / Morikami, Kenji / Yoshinari, Kiyoshi / Yoshida, Miyuki / Kondoh, Osamu et al. | 2011
- 1773
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Structure–activity relationship studies on 1-(5-carboxyindol-1-yl)-propan-2-one inhibitors of human cytosolic phospholipase A2α: Variation of the activated ketone moietyKaptur, Martina / Elfringhoff, Alwine Schulze / Lehr, Matthias et al. | 2011
- 1773
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Structure-activity relationship studies on 1-(5-carboxyindol-1-yl)-propan-2-one inhibitors of human cytosolic phospholipase A2a: Variation of the activated ketone moietyKaptur, M. / Elfringhoff, A. S. / Lehr, M. et al. | 2011
- 1777
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A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-α in activated RAW 264.7 cellsNhiem, Nguyen Xuan / Tai, Bui Huu / Quang, Tran Hong / Kiem, Phan Van / Minh, Chau Van / Nam, Nguyen Hoai / Kim, Jun-Ho / Im, Lee-Rang / Lee, Young-Mi / Kim, Young Ho et al. | 2011
- 1777
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A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-a in activated RAW 264.7 cellsNhiem, N. X. / Tai, B. H. / Quang, T. H. / Kiem, P. V. / Minh, C. V. / Nam, N. H. / Kim, J. H. / Im, L. R. / Lee, Y. M. / Kim, Y. H. et al. | 2011
- 1782
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KDR inhibitor with the intramolecular non-bonded interaction: Conformation–activity relationships of novel indole-3-carboxamide derivativesHonda, Takahiro / Nagahara, Hironori / Mogi, Hiroyuki / Ban, Masakazu / Aono, Hiroyuki et al. | 2011
- 1786
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Anti-obesity compounds in green leaves of Eucommia ulmoidesHirata, T. / Kobayashi, T. / Wada, A. / Ueda, T. / Fujikawa, T. / Miyashita, H. / Ikeda, T. / Tsukamoto, S. / Nohara, T. et al. | 2011
- 1792
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A novel alkaloid, aristopyridinone A and anti-inflammatory phenanthrenes isolated from Aristolochia manshuriensisChung, Yu-Ming / Chang, Fang-Rong / Tseng, Tseng-Fu / Hwang, Tsong-Long / Chen, Lei-Chin / Wu, Shou-Fang / Lee, Chia-Lin / Lin, Zu-Yau / Chuang, Li-Yeh / Su, Jinu-Huang et al. | 2011
- 1795
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Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agentIsshiki, Yoshiaki / Kohchi, Yasunori / Iikura, Hitoshi / Matsubara, Yasuaki / Asoh, Kohsuke / Murata, Takeshi / Kohchi, Masami / Mizuguchi, Eisaku / Tsujii, Shinji / Hattori, Kazuo et al. | 2011
- 1802
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Synthesis, characterization and anti-tumor activity of moxifloxacin–Copper complexes against breast cancer cell linesPatitungkho, Sommai / Adsule, Shreelekha / Dandawate, Prasad / Padhye, Subhash / Ahmad, Aamir / Sarkar, Fazlul H. et al. | 2011
- 1807
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hNK2 receptor antagonists. The use of intramolecular hydrogen bonding to increase solubility and membrane permeabilityEttorre, Alessandro / D’Andrea, Piero / Mauro, Sandro / Porcelloni, Marina / Rossi, Cristina / Altamura, Maria / Catalioto, Rose M. / Giuliani, Sandro / Maggi, Carlo Alberto / Fattori, Daniela et al. | 2011
- 1810
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1-((3S,4S)-4-Amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetesAndrews, Kim M. / Beebe, David A. / Benbow, John W. / Boyer, David A. / Doran, Shawn D. / Hui, Yu / Liu, Shenping / McPherson, R. Kirk / Neagu, Constantin / Parker, Janice C. et al. | 2011
- 1815
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4-Aminopyrimidine-5-carbaldehyde oximes as potent VEGFR-2 inhibitors. Part IIHuang, Shenlin / Li, Ronghua / LaMontagne, Kenneth R. / Greenberger, Lee M. / Connolly, Peter J. et al. | 2011
- 1819
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The synthesis and structure–activity relationship of pyridazinones as glucan synthase inhibitorsTing, Pauline C. / Kuang, Rongze / Wu, Heping / Aslanian, Robert G. / Cao, Jianhua / Kim, David W. / Lee, Joe F. / Schwerdt, John / Zhou, Gang / Wainhaus, Samuel et al. | 2011
- 1823
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Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitorsAl-Hourani, Baker Jawabrah / Sharma, Sai Kiran / Mane, Jonathan Y. / Tuszynski, Jack / Baracos, Vickie / Kniess, Torsten / Suresh, Mavanur / Pietzsch, Jens / Wuest, Frank et al. | 2011
- 1827
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Design and synthesis of novel CCR2 antagonists: Investigation of non-aryl/heteroaryl binding motifsTrujillo, John I. / Huang, Wei / Hughes, Robert O. / Joseph Rogier, D. / Turner, Steven R. / Devraj, Rajesh / Morton, Philip A. / Xue, Chu-Biao / Chao, Ganfeng / Covington, Maryanne B. et al. | 2011
- 1832
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Maintaining potent HTLV-I protease inhibition without the P3-cap moiety in small tetrapeptidic inhibitorsNguyen, Jeffrey-Tri / Kato, Keiko / Kumada, Henri-Obadja / Hidaka, Koushi / Kimura, Tooru / Kiso, Yoshiaki et al. | 2011
- 1838
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Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitorBowers, Simeon / Truong, Anh P. / Neitz, R. Jeffrey / Neitzel, Martin / Probst, Gary D. / Hom, Roy K. / Peterson, Brian / Galemmo, Robert A. Jr. / Konradi, Andrei W. / Sham, Hing L. et al. | 2011
- 1844
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Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitorsFang, Xingang / Chen, Yen Ting / Sessions, E. Hampton / Chowdhury, Sarwat / Vojkovsky, Tomas / Yin, Yan / Pocas, Jennifer R. / Grant, Wayne / Schröter, Thomas / Lin, Li et al. | 2011
- 1849
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Organelle-selective energy transfer: A fluorescent indicator of intracellular environmentLoudet, Aurore / Ueno, Yuichiro / Wu, Liangxing / Jose, Jiney / Barhoumi, Rola / Burghardt, Robert / Burgess, Kevin et al. | 2011
- 1852
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Optimisation of ITK inhibitors through successive iterative design cyclesHerdemann, Matthias / Weber, Alexander / Jonveaux, Jérôme / Schwoebel, Frank / Stoeck, Michael / Heit, Isabelle et al. | 2011
- 1857
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5-Oxo-15-HETE: Total synthesis and bioactivityPatel, Pranav / Anumolu, Jaganmohan R. / Powell, William S. / Rokach, Joshua et al. | 2011
- 1861
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Thienopyrrole acetic acids as antagonists of the CRTH2 receptorBonafoux, Dominique / Abibi, Ayome / Bettencourt, Brian / Burchat, Andrew / Ericsson, Anna / Harris, Christopher M. / Kebede, Tegest / Morytko, Michael / McPherson, Michael / Wallace, Grier et al. | 2011
- 1865
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Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β3 adrenergic receptor agonistsMorriello, Gregori J. / Wendt, Harvey R. / Bansal, Alka / Salvo, Jerry Di / Feighner, Scott / He, Jiafang / Hurley, Amanda L. / Hreniuk, Donna L. / Salituro, Gino M. / Reddy, Marat Vijay et al. | 2010
- 1865
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Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human b3 adrenergic receptor agonistsMorriello, G. J. / Wendt, H. R. / Bansal, A. / Salvo, J. D. / Feighner, S. / He, J. / Hurley, A. L. / Hreniuk, D. L. / Salituro, G. M. / Reddy, M. V. et al. | 2011
- 1871
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Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonistsNapier, Susan E. / Letourneau, Jeffrey J. / Ansari, Nasrin / Auld, Douglas S. / Baker, James / Best, Stuart / Campbell-Wan, Leigh / Chan, Jui-Hsiang / Craighead, Mark / Desai, Hema et al. | 2010
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Hepatitis C NS5B polymerase inhibitors: Functional equivalents for the benzothiadiazine moietyHutchinson, Douglas K. / Flentge, Charles A. / Donner, Pamela L. / Wagner, Rolf / Maring, Clarence J. / Kati, Warren M. / Liu, Yaya / Masse, Sherie V. / Middleton, Tim / Mo, Hongmei et al. | 2010
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Synthesis and evaluation of [(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]cyclohexanes and 4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]piperidines as DPP-4 inhibitorsChen, Ping / Caldwell, Charles G. / Ashton, Wallace / Wu, Joseph K. / He, Huaibing / Lyons, Kathryn A. / Thornberry, Nancy A. / Weber, Ann E. et al. | 2010
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Toxic polyketides produced by Fusarium sp., an endophytic fungus isolated from Melia azedarachYang, Sheng-Xiang / Gao, Jin-Ming / Zhang, Qiang / Laatsch, Hartmut et al. | 2010
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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacySweis, Ramzi F. / Hunt, Julianne A. / Kallashi, Florida / Hammond, Milton L. / Chen, Ying / Eveland, Suzanne S. / Guo, Qiu / Hyland, Sheryl A. / Milot, Denise P. / Cumiskey, Anne-Marie et al. | 2010
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Synthesis and SAR of sulfoxide substituted carboxyquinolines as NK3 receptor antagonistsXiong, Hui / Kang, James / Woods, James M. / McCauley, John P. Jr. / Koether, Gerard M. / Albert, Jeffrey S. / Hinkley, Lindsay / Li, Yan / Gadient, Reto A. / Simpson, Thomas R. et al. | 2010
- 1900
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Corrigendum to “Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models” [Bioorg. Med. Chem. Lett. 21 (2011) 463]Mesaros, Eugen F. / Burke, Jason P. / Parrish, Jonathan D. / Dugan, Benjamin J. / Anzalone, Andrew V. / Angeles, Thelma S. / Albom, Mark S. / Aimone, Lisa D. / Quail, Matthew R. / Wan, Weihua et al. | 2011
- 1901
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Corrigendum to “Identification of a sulfonoquinovosyldiacylglyceride from Azadirachta indica and studies on its cytotoxic activity and DNA binding properties” [Bioorg. Med. Chem. Lett. 20 (2010) 6699–6702]Chatterjee, Ratna / Singh, Omkar / Pachuau, Lalawmpuii / Malik, Shiba Prasad / Paul, Mausumi / Bhadra, Kakali / Paul, Santanu / Kumar, Gopinatha Suresh / Mondal, Nirup Bikash / Banerjee, Sukdeb et al. | 2011
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Corrigendum to “A novel screening model for the molecular drug for diabetes and obesity based on tyrosine phosphatase Shp2” [Bioorg. Med. Chem. Lett. 21 (2011) 874]Bu, Yanyan / Shi, Tao / Meng, Minghui / Kong, Guiping / Tian, Yingpu / Chen, Quancheng / Yao, Xinsheng / Feng, Gensheng / Chen, Haifeng / Lu, Zhongxian et al. | 2010
- IFC
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Editorial board| 2011