Discrete Molecular Dynamics Distinguishes Nativelike Binding Poses from Decoys in Difficult Targets (English)
- New search for: Proctor, Elizabeth A.
- New search for: Proctor, Elizabeth A.
- New search for: Yin, Shuangye
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In:
Biophysical journal
;
102
, 1
; 144-152
;
2012
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ISSN:
- Article (Journal) / Print
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Title:Discrete Molecular Dynamics Distinguishes Nativelike Binding Poses from Decoys in Difficult Targets
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Contributors:
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Published in:Biophysical journal ; 102, 1 ; 144-152
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Publisher:
- New search for: Biophysical Soc.
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Place of publication:Bethesda, Md.
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Publication date:2012
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ISSN:
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ZDBID:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
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Table of contents – Volume 102, Issue 1
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1
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Micro- and Macrorheology of Jellyfish Extracellular MatrixGambini, Camille et al. | 2012
- 10
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Blood Clot Formation under Flow: The Importance of Factor XI Depends Strongly on Platelet CountFogelson, Aaron L. et al. | 2012
- 19
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Stability and Multiattractor Dynamics of a Toggle Switch Based on a Two-Stage Model of Stochastic Gene ExpressionStrasser, Michael et al. | 2012
- 30
-
Extracting Surface Activation Time from the Optically Recorded Action Potential in Three-Dimensional MyocardiumWalton, Richard D. et al. | 2012
- 39
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Protein Translocation through Tom40: Kinetics of Peptide ReleaseMahendran, Kozhinjampara R. et al. | 2012
- 48
-
A Novel Phase of Compressed Bilayers That Models the Prestalk Transition State of Membrane FusionQian, Shuo et al. | 2012
- 56
-
Lipid-Protein Interactions Alter Line Tensions and Domain Size Distributions in Lung Surfactant MonolayersDhar, Prajnaparamita et al. | 2012
- 66
-
Force Spectroscopy Reveals the Effect of Different Ions in the Nanomechanical Behavior of Phospholipid Model Membranes: The Case of Potassium CationRedondo-Morata, Lorena et al. | 2012
- 75
-
Two-Component Coarse-Grained Molecular-Dynamics Model for the Human Erythrocyte MembraneLi, He et al. | 2012
- 85
-
Quantitative Analysis of the Nanopore Translocation Dynamics of Simple Structured PolynucleotidesSchink, Severin et al. | 2012
- 96
-
Bandpass Filtering of DNA Elastic Modes Using Confinement and TensionLin, Jun et al. | 2012
- 101
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A Kinetic Zipper Model with Intrachain Interactions Applied to Nucleic Acid Hairpin Folding KineticsKuznetsov, Serguei V. et al. | 2012
- 112
-
Molecular Dynamics Simulation of Shear- and Stretch-Induced Dissociation of P-Selectin/PSGL-1 ComplexKang, Yingyong et al. | 2012
- 121
-
Pressure-Accelerated Dissociation of Amyloid Fibrils in Wild-Type Hen LysozymeShah, Buddha R. et al. | 2012
- 127
-
Role of Channel Lysines and the “Push Through a One-Way Valve” Mechanism of the Viral DNA Packaging MotorFang, Huaming et al. | 2012
- 136
-
NMR Solution Structure of Rat Aβ(1–16): Toward Understanding the Mechanism of Rats' Resistance to Alzheimer's DiseaseIstrate, Andrey N. et al. | 2012
- 136
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NMR Solution Structure of Rat Ab(1-16): Toward Understanding the Mechanism of Rats Resistance to Alzheimers DiseaseIstrate, A. N. / Tsvetkov, P. O. / Mantsyzov, A. B. / Kulikova, A. A. / Kozin, S. A. / Makarov, A. A. / Polshakov, V. I. et al. | 2012
- 144
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Discrete Molecular Dynamics Distinguishes Nativelike Binding Poses from Decoys in Difficult TargetsProctor, Elizabeth A. et al. | 2012
- 152
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The Role of Gln61 in HRas GTP Hydrolysis: A Quantum Mechanics/Molecular Mechanics StudyMartín-García, Fernando et al. | 2012
- 158
-
Energy Landscape of the Prion Protein Helix 1 Probed by Metadynamics and NMRCamilloni, Carlo et al. | 2012
- 168
-
α−α Cross-Links Increase Fibrin Fiber Elasticity and StiffnessHelms, Christine C. et al. | 2012
- 168
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a-a Cross-Links Increase Fibrin Fiber Elasticity and StiffnessHelms, C. C. / Ariens, R. A. / Uitte de Willige, S. / Standeven, K. F. / Guthold, M. et al. | 2012
- 176
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Distribution of Sialic Acids on Mucins and Gels: A Defense MechanismBaos, S.C. et al. | 2012
- L01
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Direct Measurement of the Mechanical Properties of Lipid Phases in Supported BilayersPicas, L. / Rico, F. / Scheuring, S. et al. | 2012
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A Molecular Dynamics Study on the Effect of Disulfide Bonds in Cys-Loop Ligand-Gated GABAA ReceptorsCarpenter, Timothy S. et al. | 2012
-
Modification of Lipid Membrane Rigidity by the Yeast and Human Sar1 Vesicle Trafficking ProteinsLoftus, Andrew F. et al. | 2012
-
Integrating Theory, Simulations and Experiments to Reveal the Recognition-Specific Pathways in the Nuclear Co-Activator Binding Domain EnsembleRamanathan, Arvind et al. | 2012
-
Purification and In Vitro Functional Analysis of Glutamate ReceptorJoo Lee, Sun et al. | 2012
-
Structural and Mechanistic Insights into Gating of K2P ChannelsRapedius, Markus et al. | 2012
-
MscCG - A Mechanosensitive Channel from Corynebacterium Glutamicum with Dual FunctionBecker, Michael et al. | 2012
-
Measuring the Opening of MscL using Alternating Laser Excitation (ALEX) FRETWang, Yong et al. | 2012
-
The β1B Subunit Regulates the Activity of LVA Calcium Channels: Evidences for a Physical InteractionArteaga-Tlecuitl, Rogelio et al. | 2012
-
Rare Missense Mutations in the Calcium Channel β2 Subunit Gene of Autistic Patients Reduce Time-Dependent Inactivation of CaV1.2Breitenkamp, Alexandra F. et al. | 2012
-
Rescuing Proper Trafficking of Cysteine Mutant ProteinsLopez-Rodriguez, Angelica M. et al. | 2012
-
Matrix Metalloproteinase-9 Increases the Ligand Sensitivity of CNG Channels: Evidence for Sequential Subunit ModificationMeighan, Peter C. et al. | 2012
-
Modulation of EAG Channel Inactivation by ICA105574Garg, Vivek et al. | 2012
-
The Mechano-Activated Potassium Channel from Human Erythrocyte (HEMKCA): Effect of Oxidative Stress and its Implication on the Senescence ProcessRomero, Jesus G. et al. | 2012
-
Palmitate Improves Basal and β-Stimulated Left Ventricle Function in Diabetic Mouse HeartsCaceres, Viviane et al. | 2012
-
Single-Molecule DNA Repair in Live BacteriaUphoff, Stephan et al. | 2012
-
Spatially-Resolved Measurements of Bacillus Subtilis Cell Wall Growth Dynamics during Elongation and DivisionDeng, Yi et al. | 2012
-
Complex In Vitro Motility Characteristics Emerge from Mechanical Coupling of Myosin Motors via a Commonly Propelled Actin FilamentHilbert, Lennart et al. | 2012
-
Slow Myosin ATP Turnover in the Super-Relaxed State in Tarantula MusclePate, Edward et al. | 2012
-
Maximal Coherence at Room Temperature in the Bacterial Photosynthetic Reaction CenterLong, Phillip D. et al. | 2012
-
The Effects of Phosphate and Hydrogen Ions on the Velocity-pCa Relationship in a Motility AssayDebold, Edward P. et al. | 2012
-
The Functional Consequences of HCM Troponin C Mutations in the Regulation of Slow Skeletal Muscle ContractionDweck, David et al. | 2012
-
Two Voltage-Gated Calcium Channels Regulate Calcium Uptake in Murine Cardiac MitochondriaJaroslaw Motloch, Lukas et al. | 2012
-
Effect of Hypertrophic Cardiomyopathy Linked Troponin C Mutations on the Calcium Sensitivity of Acto-Myosin ATPase under Different Phosphorylation States of Troponin IAlbury, Acchia et al. | 2012
-
Towards Fast and Accurate Calculation of Protein pKa Values Exploiting Various Degrees of Conformational FlexibilityPraneeth Kilambi, Krishna et al. | 2012
-
Subnanometer Structure of the Actin/Myosin/Tropomyosin ComplexBehrmann, Elmar et al. | 2012
-
Modeling the Sequence Dependent Rigidity of DNA with a Molecular Dynamics Parameterized Rigid Base ModelMitchell, Jonathan S. et al. | 2012
-
Increased Activity of Mitochondrial Complex II in Rabbit Heart Failure is Associated with Reactive Oxygen Species Generation and Impaired Excitation-Contraction CouplingSeidlmayer, Lea K. et al. | 2012
-
In Vivo Investigation of Calpain Activity by Lifetime Imaging of Genetically Encoded FRET SensorsSardini, Alessandro et al. | 2012
-
Second-Chance Signal Transduction is a Model for Bacterial Flagellar Switching and Tropomyosin-Based MotilityZot, Henry G. et al. | 2012
-
Measuring DNA Bending and Twisting Flexibility in E. ColiBecker, Nicole A. et al. | 2012
-
The Stability and Dynamics of E-Coli Beta-Clamp by Single Molecule and Fluorescence Correlation SpectroscopyRanjit, Suman et al. | 2012
-
An Improved Meta-Analysis Procedure Reveals Key Transcriptome Signatures Underlying a Renal Damage PhenotypeBai, Yu et al. | 2012
-
The Molecular Refractive Function of Lens Gamma CrystallinsZhao, Huaying et al. | 2012
-
Non-Gaussianity in Single Particle Tracking: Use of Kurtosis to Learn the Characteristics of a Cage-Type PotentialLushnikov, Pavel M. et al. | 2012
-
A Microfluidic-Based Tyrosine Kinase and Phosphatase AssayNevenzel, Hadas et al. | 2012
-
Viscoelastic Response of Red Blood Cells in Linear Optical TrapsSawetzki, Tobias et al. | 2012
-
Single-Molecule Investigation of Phycobilisome Energy Transfer MechanismsKessler, Jonathan M. et al. | 2012
-
De Novo Design of Protein Binders: Targeting Human IgG (Fc)Strauch, Eva-Maria et al. | 2012
-
Photosensitization Mechanism in Lipid Membranes: The Role of Hydroperoxide LipidsJunqueira, Helena C. et al. | 2012
-
Dopamine Receptor Signaling in the Pancreatic β-CellUstione, Alessandro et al. | 2012
-
Computational Modeling of Glycolipid-Glycoprotein Complexes: Methods and ApplicationsDeMarco, Mari et al. | 2012
-
Computational Investigation of Graphene Nano Pore DNA DetectionSathe, Chaitanya et al. | 2012
-
Protein-Ligand Binding by Free Energy Simulations: Issues, Successes and FailuresEssex, Jonathan W. et al. | 2012
-
Metal Organic Materials as Biomimetic Heme CatalystsLarsen, Randy W. et al. | 2012
-
Distribution Characterization with Fluorescence Cumulant AnalysisOlson, Eben et al. | 2012
-
Far Field Fluorescence and AFM Superposition with 10nm Special ResolutionHodges, Jeffery et al. | 2012
-
Lipid and Detergent Effects on the Kinetic Stability of the GPCR, RhodopsinAlbert, Arlene et al. | 2012
-
Visualizing the Interaction of Kinetochores Complexes with MicrotubulesNogales, Eva et al. | 2012
-
Visualization of Troponin on Muscle Thin Filaments by Single Particle AnalysisYang, Shixin et al. | 2012
-
Computational Electrophysiology Reveals Ion Channel Permeation in Atomistic DetailZachariae, Ulrich et al. | 2012
-
From Force-Fields to Photons: MD Simulations of Dye-Labeled Nucleic Acids and Monte Carlo Modeling of FRETMilas, Peker et al. | 2012
-
Invisible Binding: DnaA, the Initiator of Chromosome Replication in Bacteria, Associates with the Escherichia Coli Inner Membrane In VivoRegev, Tomer et al. | 2012
-
Inositol 1,4,5 Trisphosphate Receptor Type 1 (IP3R1) Activate Ryanodine Receptor (RyR1) to Mediate Ca2+ Spark Signaling in Adult Mammalian Skeletal MuscleTjondrokoesoemo, Andoria et al. | 2012
-
Association-Dissociation Dynamics of Transmembrane Helices as Detected by Single-Molecule Fluorescence MicroscopyYano, Yoshiaki et al. | 2012
-
Characteristics and Mechanisms of Fluid Pressure-Induced Ca2+ Waves in Atrial MyocytesWoo, Sun-Hee et al. | 2012
-
Investigating the Interaction Between Characterized Amyloid-Beta Oligomers and the Prion Protein Receptor in Live CellsNarayan, Priyanka et al. | 2012
-
Role of (httNT) α-Helix Formation in Huntingtin N-Terminal Fragment AggregationMishra, Rakesh et al. | 2012
-
Ligand Dynamics during Microsecond Simulations of the A2a Adenosine ReceptorYoung Lee, Ji et al. | 2012
-
Evaluation of the Amyloid Fibril StabilityKurouski, Dmitry et al. | 2012
-
RNA Editing of the IQ Domain in CaV1.3 Channels Modulates their Ca2+-Dependent InactivationHuang, Hua et al. | 2012
-
Evolution of Protein Architecture for Mechanical FunctionDebès, Cédric et al. | 2012
-
Rotary Motion of FOF1-ATP Synthase in the Presence of pmfWatanabe, Rikiya et al. | 2012
-
Membrane Protein Secondary Structure Determination via Pulsed EPR ESEEMZhou, You et al. | 2012
-
A New Secretory Phospholipase A2 from Glycine Max Soybean: Purification, Characterization and Kinetic AnalysisMariani, Maria E. et al. | 2012
-
Why Proteins Crystallize (or not): The Role of Non Specific Protein InteractionsFusco, Diana et al. | 2012
-
Single Molecule Studies of the Effect of Spermidine on DNA Mechanics and Viral DNA PackagingKeller, Nicholas A. et al. | 2012
-
Chemical Imaging of the Lipid and Cholesterol Distribution in the Plasma Membranes of Intact CellsKraft, Mary L. et al. | 2012
-
A Single Molecule Kinetic and Thermodynamic Approach to Oligonucleotide Duplex FormationDupuis, Nicholas F. et al. | 2012
-
Structure-Function Relationships Within the Hepatitis Delta Virus RibozymeSripathi, Kamali et al. | 2012
-
Characterizing an Intermediate State Between Inactive and Active States of RecAJiang, Tao et al. | 2012
-
ATP-Induced Helicase Slippage Reveals Highly Coordinated SubunitsSun, Bo et al. | 2012
-
Secondary Structure Formation by Bilayer-Active Peptides Studied by Freeze-Fracture Electron Microscopy: From Disc Micelles to Cochleate CylinderPapahadjopoulos-Sternberg, Brigitte et al. | 2012
-
Use of Fast DNA Footprinting and Real-Time Fluorescence Spectroscopy to Characterize Novel, Biologically Revlevant Transcription Initiation Intermediates for E. Coli RNA PolymeraseHeitkamp, Sara et al. | 2012
-
Single Molecule DNA Interactions Between the E. Coli DNA Polymerase III α Subunit and the Polymerase Manager Protein UmuDRuslie, Clarissa et al. | 2012
-
Studying RecA Homology Search Mechanism using Single-Molecule MethodsLiao, Song-Mao et al. | 2012
-
Nanoparticle and Surfactant Interactions with Model Cell MembranesCuculis, Luke et al. | 2012
-
Architecture of the Mediator Head ModuleTakagi, Yuichiro et al. | 2012
-
Lipid Droplets are Polarized during G2 Phase and Increase in Number at the Septum after its Formation in Fission Yeast CellsMeyers, Alex et al. | 2012
-
Cholesterol Mediates Membrane Curvature during Fusion EventsIvankin, Andrey et al. | 2012
-
Calculating Elastic Constants and the Effects of Curvature on the Binding of Lipid Chain Anchors to DPPC/DOPC/Cholesterol Model Lipid BilayersUline, Mark et al. | 2012
-
Modular Thermal Sensors in Temperature-Gated TRP ChannelsQin, Feng et al. | 2012
-
S-Adenosyl-L-Methionine Induced RyR2 Subconductance: Evidence for an Allosteric MechanismBalog, Edward M. et al. | 2012
-
Solution NMR as an Investigational Tool for Disordered and Partly Folded ProteinsJane Dyson, H. et al. | 2012
-
Stretch-Dependent Sub-Cellular Ca2+ Signaling in Atrial MyocytesGreiser, Maura et al. | 2012
-
Modulating the Mitochondrial F0F1-ATPase as Therapeutic Strategy for Systematic AutoimmunityGlick, Gary D. et al. | 2012
-
Partitioning, Diffusion, and Ligand Binding of Raft Lipid Analogs in Model and Cellular Plasma MembranesSezgin, Erdinc et al. | 2012
-
Dantrolene-Sensitive Mitochondrial Ca2+ Uptake under Mitochondrial Ca2+ Uniporter InhibitionPan, Shi et al. | 2012
-
Rapid Changes in Mitochondrial Ca2+-Concentration in Fast Skeletal Muscle Fibers from Wild Type and Calsequestrin Null MiceScorzeto, Michele et al. | 2012
-
Gated Regulation of CRAC Channel Ion Selectivity by STIM1McNally, Beth et al. | 2012
-
Influenza Virus Hemagglutinin Delays Endosomal Acidification - a Strategy for Successful Delivery of the Viral Genome?Sieben, Christian et al. | 2012
-
Role of Rac1-GTPase in Glucose Inhibition of Glucagon SecretionElliott, Amicia D. et al. | 2012
-
Novel Modulators of STIM-ORAI Calcium Entry PathwayQuintana, Ariel et al. | 2012
-
Stochastic Nature of Clathrin-Coated Pit AssemblyBanerjee, Anand et al. | 2012
-
Structural Analysis of Dynamin Reveals Power StrokeHinshaw, Jenny E. et al. | 2012
-
A Novel Sorting Prevention Mechanism Mediated by HID-1 during Early Biogenesis of Dense Core VesiclesXu, Tao et al. | 2012
-
Phosphoinositide Regulation of TRPV1Lukacs, Viktor et al. | 2012
-
On the Potential Interaction between Non-Selective Cation Channel TRPM4 and the Sulfonylurea Receptor SUR1Sala-Rabanal, Monica et al. | 2012
-
The Investigation of Lipid Membrane Deformation in Giant Unilamellar Vesicles using Microfluidic TechnologyRobinson, Tom et al. | 2012
-
GαQ/Gα11 Modulate Aldosterone Mediated Electrical Remodeling and Ca2+ Handling Alterations in Ventricular MyocytesPahlavan, Sara et al. | 2012
-
A Two-State Eukaryotic Cell Migration ModelYogurtcu, Osman N. et al. | 2012
-
Distinct Roles for Talin-1 and Kindlin-3 in Regulating LFA-1 Conformation during Neutrophil Rolling and ArrestLefort, Craig T. et al. | 2012
-
Half-Sarcomeres with Heterogeneous Crossbridge Populations can be Stabilized by Accompanying Variations in Titin FilamentsCampbell, Stuart G. et al. | 2012
-
Geometric Changes of Transverse Tubules in Rabbit Cardiac Myocytes during ContractionMcNary, Thomas G. et al. | 2012
-
Mechanoregulation of Delayed Stretch ActivationMijailovich, Srboljub M. et al. | 2012
-
From Single Molecule Fluctuation to Muscle Contraction: A Brownian Model of A.F. Huxley's HypothesesMarcucci, Lorenzo et al. | 2012
-
Dual Roles of Extracellular Calcium in Excitation-Contraction Coupling of Mouse Skeletal MuscleFerreira, Juan et al. | 2012
-
Exploration and Suppression of Cardiac Amyloidosis Induced by Huntington's Disease-Causing Amyloid in the Drosophila Heart ModelMelkani, Girish C. et al. | 2012
-
Cardiocyte Functional Data Analysis: A Novel ApproachVazquez-Hidalgo, Esteban et al. | 2012
-
Regulating Intracellular Transport with External StimuliRadhakrishnan, Anand et al. | 2012
-
Intracellular Trafficking of Lipid Gene Vectors Investigated by Three-Dimensional Single Particle TrackingCoppola, Stefano et al. | 2012
-
Mitochondria - A Potential Roadblock for Axonal TransportChe, Daphne L. et al. | 2012
-
Study of BDNF Transcytosis in Hippocampal NeuronsXie, Wenjun et al. | 2012
-
Structural and Biochemical Study of the Interaction Between Actin and the Mammalian Formin FMNL3Thompson, Morgan E. et al. | 2012
-
Novel Modulation of the S.Cerevsiae Actin-Cyctokeleton by Heterologous Expression of the Short N.Crassa TropomyosinEbrahim, Seham et al. | 2012
-
Understanding mRNA Transport during Developing Hippocampal Neurons and during Neuron RegenerationPathak, Gunja et al. | 2012
-
A Biochemical Model for Sub-Cellular Waves of Actin ActivityHolmes, William R. et al. | 2012
-
Nuclear Localization of mDia2 Formin and its Possible Regulation by Rho Family GTPasesShao, Xiaowei et al. | 2012
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Solution Conformation of Extracellular Matrix ProteinsPatel, Trushar R. et al. | 2012
-
Three Dimensional Single Molecule Tracking of Full Length Myosin Conformation ChangeSheung, Janet Y. et al. | 2012
-
Modeling the Endosomal Escape of Labeled Cell Penetrating PeptidesMadani, Fatemeh et al. | 2012
-
Diffusion inside Living Human CellsLeijnse, Natascha et al. | 2012
-
Combining Super-Resolution Imaging and Single Particle Tracking in Living Cells to Probe Interactions Between Actin and Plasma Membrane ProteinsHiggins, Jenny L. et al. | 2012
-
Crowding of Molecular Motors Determines Microtubule DepolymerizationReese, Louis et al. | 2012
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Kinesin Backstepping Under 3D LoadCross, Robert et al. | 2012
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Development of a Force Field Topology Database for Detergents for Molecular Dynamics Simulations with the Amber Force FieldsAbel, Stéphane et al. | 2012
-
CLC Transporters: The Search for Conformational ChangeMaduke, Merritt et al. | 2012
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Electropore Dynamics in Time-Dependent Electric FieldsLevine, Zachary A. et al. | 2012
-
Impact of Sterol Tilt on Membrane Bending Rigidity in Cholesterol and 7DHC-Containing DMPC MembraneKhelashvili, George et al. | 2012
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Enhanced Lipid Diffusion and Mixing in Accelerated Molecular DynamicsWang, Yi et al. | 2012
-
Unified Description of Optical Properties and Photostability of Fluorescent Proteins by Means of the Chromophore-Protein Electrostatic InteractionsDrobizhev, Mikhail et al. | 2012
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Aggregated yet Disordered: A Molecular Simulation Study of the Self-Aggregation of ElastinRauscher, Sarah et al. | 2012
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pH Replica-Exchange Method Based on Discrete Protonation StatesItoh, Satoru G. et al. | 2012
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Synchronization of Swimming MicroorganismsElfring, Gwynn J. et al. | 2012
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Computer Aided Distance Reconstruction in Single Molecule FRET Experiments through Combination with Dye Dynamics from Molecular Dynamics SimulationsHoefling, Martin et al. | 2012
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A Comparison Between ADIFAB and Reporter Vesicles in the Measurement of PLA2 ActivityOcampo Ariza, Hector J. et al. | 2012
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Specificity, Structure and Dynamics of Tiam1 PDZ Domain Ligand-Bound ComplexesFuentes, Ernesto J. et al. | 2012
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A Prokaryotic Perspective on Pentameric Ligand-Gated Ion Channel Structure and FunctionDutzler, Raimund et al. | 2012
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Probing the Structural and Dynamic Properties of KCNE1 using Site-Directed Spin Labeling EPR SpectroscopyTroxel, Kaylee R. et al. | 2012
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The Ring of Glutamates in the Charge-Selectivity Filter Region of the Nicotinic Receptor Forms a System of Unanticipated ComplexityCymes, Gisela D. et al. | 2012
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Simulation Studies of Transport of Hydrophobic Compounds through Outer Membrane Proteins of Gram Negative BacteriaChohan, Pragya et al. | 2012
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Twist, Stretch and Melt: Quantifying How DNA Complies to TensionGross, Peter et al. | 2012
-
How PIP2 Lipids Regulate the Position and Phosphorylation of the Syntaxin N-TerminusKhelashvili, George et al. | 2012
-
The Structure of the Chemokine Receptor CXCR1 in Phospholipid Bilayers and Interactions with IL-8Ho Park, Sang et al. | 2012
-
Nanopore Analysis of Individual RNA/Antibiotic ComplexesWanunu, Meni et al. | 2012
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Structure-Function Investigation of a Transglycosylase Associated Protein from Mycobacterium TuberculosisMurray, Dylan T. et al. | 2012
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Structural Basis for the Mg2+-Dependent Modulation of Calmodulin ActivitySenguen, F. Timur et al. | 2012
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Plasticity of the Asialoglycoprotein Receptor Deciphered by Ensemble FRET and Single-Molecule Counting PALMRenz, Malte et al. | 2012
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Bcl-xL Increases Bax Mitochondrial Localization and Activation in Non-Apoptotic CellsDejean, Laurent M. et al. | 2012
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Persistent α-Helical Content and Local Helical Structural Fluctuations from a Molten Globule to Ordered Peptide TransitionBrown, Mia et al. | 2012
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Amyloid Beta Misfolds and Increases its Affinity for Cell Membranes at the Initial Step of AggregationNag, Suman et al. | 2012
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Dynamic Motions of the G Protein Subunit G Alpha I1 While Complexed to the GEF Ric-8ABlack, Labe et al. | 2012
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Evaluating the Consequences of Adsorption-Induced Structural Perturbations of ProteinsFelsovalyi, Flora et al. | 2012
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The Geometrical Origins of a Protein Folding MechanismLammert, Heiko et al. | 2012
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Peptides - Beta-Sheet Folding from Hairpins to AggregatesKeiderling, Timothy A. et al. | 2012
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Prediction of Thermostable Mutants of G-Protein Coupled Receptor Proteins using Knowledge-Based Energy FunctionsMueller, Daniela S. et al. | 2012
-
Role of Local Metal-Site Interactions and Bulk Protein Restraints in the Thermodynamics of Zinc Binding to a Zinc Finger ProteinDixit, Purushottam et al. | 2012
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Mapping the Oligomeric Assembly of Plasma Factor XIII A2B2 by Hydrogen-Deuterium Exchange Coupled with MALDI-TOF Mass SpectrometryMaurer, Muriel et al. | 2012
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Hugging Interaction: Asymmetric Binding of Metastasis Associated Protein S100A4 to Non-Muscle Myosin 2A TailKiss, Bence et al. | 2012
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Molecular Determinants for a Mutant Mu-Opioid Receptor in which Naloxone Acts as a Partial AgonistPearsall, Elizabeth et al. | 2012
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The Role of Electrostatics in the Function of Homologous Thioester Containing Proteins: Insights into the Evolution of the Complement C3d:Cr2 InteractionKieslich, Chris A. et al. | 2012
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Mapping the Inositol Hexakisphosphate Binding Sites on the Human Fibroblast Growth FactorHenderson, Rory et al. | 2012
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Kinetics of Ligand Receptor Interaction Reveals the Mode of Binding in Cyclic Nucleotide-Activated ProteinsPeuker, Sebastian et al. | 2012
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Thermodynamic Measurements of Bilayer Insertion of a Single Transmembrane HelixKyrychenko, Alexander et al. | 2012
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Two Tyrosyl Radicals Stabilize High Oxidation States in Cytochrome C Oxidase for Efficient Energy Conservation and Proton TranslocationRousseau, Denis L. et al. | 2012
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Opposing Effects of Proline and Calcium Binding Lead to Plasticity in Adhesive Dimers of Neural-CadheirnVunnam, Nagamani et al. | 2012
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A New Role for UvrB in NER? Single Molecule Imaging of the NER Complex UvrBC-DNAHughes, Craig D. et al. | 2012
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Substrate Interactions of a Human DNA AlkyltransferaseFried, Michael G. et al. | 2012
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Atomistic Modeling of Excluded-Volume and Soft Interactions in Crowded EnvironmentsQin, Sanbo et al. | 2012
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Competitive Binding to Lipid Bilayers by Peptides and DrugsLee, Chang-Chun et al. | 2012
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Computer Simulation of Chromatin: Interdependency Between Nucleosome Positions and Chromatin StructureMüller, Oliver et al. | 2012
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Geometric Regulation of Chromatin Remodeling is Dependent on Acto-Myosin ContractilityJain, Nikhil et al. | 2012
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Structural and Functional Consequences of Phosphate-Arsenate Substitutions in Selected Nucleotides: DNA, RNA, and ATPMa, Buyong et al. | 2012
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Transfer Free Energies from Spontaneous Bilayer Insertion of Water Soluble Trans-Membrane HelicesUlmschneider, Martin B. et al. | 2012
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Anionic Phospholipids change the Effect of the Hydrophobic Surfactant Proteins on Structures of Hexagonal LipidsChavarha, Mariya et al. | 2012
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Protection of the Membrane Permeability Barrier by AnnexinsCreutz, Carl E. et al. | 2012
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Influence of the Interdigitated Gel Phase in Mixtures of Ether-Linked and Monofluorinated Ester-Linked PhospholipidsSmith, Eric A. et al. | 2012
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A Dynamic Model of Fusion Pores in Lipid BilayersRyham, Rolf et al. | 2012
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Characterization of a Novel CLC Homolog from Citrobacter KoseriPhillips, Sabrina et al. | 2012
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Mapping Interactions Between the Amino-Terminal Region of Secretin and its Receptor using Disulfide-TrappingDong, Maoqing et al. | 2012
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Rate Constants for Anion Transport by Steroid-Based Synthetic Anion TransportersLi, Hongyu et al. | 2012
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Arrestin Allows All-Trans-Retinal to Enter the Ligand Binding Pocket of Phosphorylated OpsinSommer, Martha E. et al. | 2012
-
Eccentric Exercise Elicits Elevation of Resting Calcium in Skeletal Muscle. Periodic Acceleration Enhanced the RecoveryLopez, Jose R. et al. | 2012
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Structural Intermediates in a Model of the Substrate Translocation Path in the Bacterial Glutamate Transporter Homologue GltPhStolzenberg, Sebastian et al. | 2012
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A Proton Leak Current through the Cardiac Sodium Channel Linked to Mixed Arrhythmia and Dilated Cardiomyopathy PhenotypesGosselin-Badaroudine, Pascal et al. | 2012
-
Molecular Modelling and Experimental Analysis of the ATP Sensitivity of Cloned Smooth Muscle KATP ChannelsChadburn, Andrew et al. | 2012
-
Patient-Specific Inducible Pluripotent Stem Cells Reveal Mechanism of Personalized Therapy for an Inherited Cardiac ArrhythmiaWang, Kai et al. | 2012
-
Biophysical and Pharmacological Characterisation of Native Human NaV1.8 Channels from Isolated Dorsal Root Ganglia (DRG)Payne, Liz et al. | 2012
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A Self-Limiting Regulation of TRPC3 C6 C7 Channels Linked with PI(4,5)P2-Diacylglycerol SignalingImai, Yuko et al. | 2012
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Mechanisms for Increased Arrhythmia Risk in Aged HeartsNguyen, Thao P. et al. | 2012
-
The Molecular Basis of Phosphoinositide Activation of Human Inward Rectifier (Kir2.1) ChannelsD'Avanzo, Nazzareno et al. | 2012
-
Preferential Association with Gβγ Over Gα Governs the Activity of a G Protein-Activated K+ ChannelYakubovich, Daniel et al. | 2012
-
Pluripotent Cell-Derived Cardiomyocytes: One Cell Type as a Predictive Tool For the Assessment of Drug Efficacy and Safety on a Variety of Cardiac TargetsKettenhofen, Ralf F. et al. | 2012
-
Multiple, Dynamic, Packing Strategies of Ryanodine Receptors in VentricleAsghari, Parisa et al. | 2012
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How Spatiotemporal Clustering of L-Type Ca2+ Channels Regulates Ca2+ Signals in Rat Ventricular Myocytes?Cheng, Yuhui et al. | 2012
-
The Effects of C-Terminal Mutations on the Folding of Cardiac Myosin Binding Protein-CHolly, Ashley et al. | 2012
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Ros and CaMKII Modulate Sodium Overload-Induced Calcium Leak from Ryanodine Receptors in Ventricular MyocytesViatchenko-Karpinski, Serge et al. | 2012
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Regulatory Light Chain Phosphorylation Mimic S15D Causes Partial Rescue of Isometric Force Production in FHC Causing Mutation D166VSchmidt, William M. et al. | 2012
-
Multiscale Simulation of Malaria-Infected Erythrocytes and Spherocytes of Hereditary Spherocytosis Passing Endothelial Slits in the SpleenPeng, Zhangli et al. | 2012
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Nrf2 Controls Mitochondrial BioenergeticsHolmstrom, Kira M. et al. | 2012
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Myosin VI Comes Together - Structure and Motor Regulation by Binding PartnersToseland, Christopher P. et al. | 2012
-
Automation of “Classical” Patch Clamp Experiments Featuring Multi Channel Recordings, Optical Cell Selection and Ultra Fast Compound ApplicationDanker, Timm et al. | 2012
-
Localization of Liquid-Ordered/Liquid-Crystalline Phase Separation at a Lipid Bilayer Suspended Over MicrowellsSumitomo, Koji et al. | 2012
-
Under Pressure: Measuring Desolvation of Model α-Helical PeptidesDonaldson, Teraya et al. | 2012
-
Modulating Contraction by Binding of MyBP-C to ActinCraig, Roger et al. | 2012
-
Molecular Structure and Stability of Phospholipid Monolayers Probed by Vibrational Sum Frequency Spectroscopy (VSFS)Liljeblad, Jonathan F.D. et al. | 2012
-
Co-Opting Moore's Law: Vaccines and Medicines made from a WaferDeSimone, Joseph M. et al. | 2012
-
Testing the Ability of Implicit Membrane Models to Discriminate the Native State of Membrane ProteinsYuzlenko, Olga et al. | 2012
-
Chromatin Dynamics: At the Source of RNA ProductionLavelle, Christophe et al. | 2012
-
Myosin V as a Point-to-Point Organelle TransporterHammer, John A. et al. | 2012
-
Building Complexity to Understand Myosin V Cargo TransportTrybus, Kathleen M. et al. | 2012
-
Single-Molecule Imaging Reveals Mechanisms of Roadblock Clearance by DNA Motor EnzymesFinkelstein, Ilya J. et al. | 2012
-
Structure, Dynamics, and Mechanism of the Leucine Transporter Studied by Double Electron Electron Resonance SpectroscopyKazmier, Kelli et al. | 2012
-
A Transgenic Mouse Model for Imaging Single RNA Dynamics In VivoYoon Park, Hye et al. | 2012
-
Oligomerization of HIV-1 Restriction Factor APOBEC3G Transforms it from a Fast Enzyme to a Slow Nucleic Acid Binding ProteinChaurasiya, Kathy R. et al. | 2012
-
Structural Relationships Between Retaining and Inverting GT-B Glycosyltransferases as Revealed by Structure Analysis of Sucrose Synthase-1 from Arabidopsis ThalianaZheng, Yi et al. | 2012
-
Computational Studies of the Molecular Mechanisms Responsible for Ca2+ Permeation and Mg2+ Block of NMDA ReceptorsVeras, Lea et al. | 2012
-
Nucleic Acid Chaperone Activity of Wild Type and Mutant FIV Nucleocapsid ProteinsWu, Hao et al. | 2012
-
Fluorescence Correlation Spectroscopy Imaging of Chromatin DynamicsWachsmuth, Malte et al. | 2012
-
Membrane Protein Function and Transmembrane Helix Backbone DynamicsLangosch, Dieter et al. | 2012
-
Rhodopsin Simulations in Detergent Micelles Characterize Meta I and Meta II PhotointermediatesMertz, Blake et al. | 2012
-
Effects of the Periplasmic Domain of BamA, the Essential Transmembrane Protein of the Beta-Barrel Assembly Machinery (BAM), in Folding and Insertion of the Outer Membrane Protein ATalmon, Esther et al. | 2012
-
Exploring the Biophysical Properties of Human Uncoupling Proteins: A Search for their Physiological Roles in the Central Nervous SystemHoang, Tuan et al. | 2012
-
New Developments on Generalized Simulated Annealing Applied to ab-initio Protein Structure PredictionMelo, Marcelo C. et al. | 2012
-
Intrinsically Disordered Regions as Affinity Tuners in Protein-DNA InteractionsLevy, Yaakov (Koby) et al. | 2012
-
Conformational Sampling of FG-Nucleoporins using Extended Molecular Dynamics SimulationsMiguel, Amanda V. et al. | 2012
-
Different Behaviors of the Structured and Unstructured Regions of Titin under PressureSomkuti, Judit et al. | 2012
-
Kinetic Enhancement of NF-KB/DNA Dissociation by IkBalphaAlverdi, Vera et al. | 2012
-
Optimal Nanocarrier Design for Cancer Cell TargetingTsekouras, Konstantinos et al. | 2012
-
Role of Membrane Oxidation in Controlling the Activity of Secretory Phospholipase A2 Toward Apoptotic Lymphoma CellsGibbons, Elizabeth et al. | 2012
-
High Resolution Characterization of Tertiary Contacts in Intrinsically Disordered Amyloidogenic States of α-Synuclein Provides New Scaffolds for Structure-Aided Drug DiscoveryBertoncini, Carlos W. et al. | 2012
-
The Difference of Apoptotic Responses in Denervated Muscle Atrophy of Aging Rat Skeletal MusclesLim, Jae-Young et al. | 2012
-
Folding and Characterization of Intrinsically Disordered Protein Human Cyclin I (Ccni)Chu, Hsueh-Liang et al. | 2012
-
Impact of Oxidized Lipids on Membrane Structure and Dynamics and its Interactions with ProteinsWallgren, Marcus et al. | 2012
-
Ultrasound-Induced Nanofragmentation of Bubbles with Saturated and Unsaturated Lipid CoatsCox, Debra J. et al. | 2012
-
Nanomanipulation of Single RNA MoleculesLi, Pan T.X. et al. | 2012
-
Functional Non-Coding RNA Coding Vascular Epigenetics: Chance and Necessity in Adaptation ReactionsWissler, Josef H. et al. | 2012
-
Single Molecule Views of the Ribosome AssemblyKim, Hajin et al. | 2012
-
Mechanism of Interaction Between Lung Surfactant Protein-D and Influenza A Virus HemagglutininChong Goh, Boon et al. | 2012
-
Native Architecture Encodes Cooperativity and Specificity in RNA Folding IntermediatesBehrouzi, Reza et al. | 2012
-
Understanding Chlorocatechol 1,2-Dioxygenase Function: A Promising Player in Bioremediation ProcessesMesquita, Nathalya C. et al. | 2012
-
Tracking Bacterial Riboregulation by DsrA Noncoding RNACayrol, Bastien et al. | 2012
-
Evidence for a TH6-TH7 Transmembrane Hairpin in the Diphtheria Toxin T-Domain Open Channel StateKienker, Paul et al. | 2012
-
Crotamine Toxicity Revisited: Novel Insights Based on KV Channel InhibitionTytgat, Jan et al. | 2012
-
Quantifying BMP2 Dynamics during Stem Cell Differentiation using, Real Time Imaging, Combined Confocal AFM and Systems Biology ApproachesAkkiraju, Hemanth et al. | 2012
-
Observation of Two-Step Unzipping of a Single SNARE Complex by using Nano-Mechanical MeasurementMin, Duyoung et al. | 2012
-
Purification of the Voltage Sensor Domain of KCNQ1 and its Interactions with Cholesterol and SphingomyelinPeng, Dungeng et al. | 2012
-
Enhanced Embryonic Stem Cell Differentiation to Cardiac Pacemaker Cells by Transduction with a Single Transcription FactorIonta, Vittoria et al. | 2012
-
Predicting Allosteric Pathways for Activation of K+ Channels by Perturbation Based Markovian Transmission ModelGursoy, Gamze et al. | 2012
-
Aberrant Functional Differentiation of Cardiac Precursors from a Dystrophic MouseAltomare, Claudia et al. | 2012
-
Investigating the Effect of Redox Agents on Structural Re-Arrangement of the BK Channel RCK1-RCK2 Linker using Fluorescence Lifetime Imaging MicroscopyRowe, Iain et al. | 2012
-
The BK Channel Opener Phloretin Influences Voltage- and Calcium-Dependent GatingGonzalez, Lorie A. et al. | 2012
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Multiple Ca2+ Binding Sites in the RCK Domain Contribute to Gating in the MthK K+ ChannelSmith, Frank J. et al. | 2012
-
The Width-Length Relationship of Mitotic Spindle in Caenorhabditis Elegans Embryonic Cells: Quantification and Implications for the Regulatory MechanismHara, Yuki et al. | 2012
-
Simulating Self-Organization of Microtubules Interacting with Motor Protein-Coated Beads in Microscopic ChambersNitta, Takahiro et al. | 2012
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Microtubule Dynamics of S. Pombe TubulinDrummond, Douglas R. et al. | 2012
-
Advances in Image Correlation Spectroscopy for Measurements in Heterogeneous Cell EnvironmentsWiseman, Paul W. et al. | 2012
-
Stu2p, the Budding Yeast Homologue of XMAP215, is a Weak Microtubule Polymerase that Promotes RescuesPodolski, Marija et al. | 2012
-
Using a Non-Averaged Displacement Analysis to Characterize Multiple Populations of Single Molecule MotionsCarter, Michael S. et al. | 2012
-
The Effect of Thrombin Concentration on Rheology of Fibrin NetworksWu, Huayin et al. | 2012
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Coupling Molecular Motions of Prestin to Cellular Motility: Effects of Voltage, Chloride and CytoskeletonSong, Lei et al. | 2012
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Revealing the Interaction of Binding Protein with ABC Transporter by Fluorescence Correlation SpectroscopyZiomkowska, Joanna et al. | 2012
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High Throughput Screening Methodology to Probe Cell DeformabilityQi, Dongping et al. | 2012
-
Interaction of SERCA with the Transmembrane Domain of Phospholamban Measured by FRET in Live CellsBidwell, Philip A. et al. | 2012
-
Interactions Between the γ Subunit and the ε Subunit Mediate Inhibition and Coupling in Escherichia Coli F1-ATPaseNegrey, Natalie C. et al. | 2012
-
Observations of MHC Structural Changes Elicited from Antigenic Peptide using Diffracted X-Ray Tracking (DXT)Sasaki, Yuji C. et al. | 2012
-
An Irreversible Lock to Proteins for Dynamic Force Spectroscopy at the Mammalian Cell SurfaceCelik, Emrah et al. | 2012
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Extracellular Matrix Proteins are Necessary for Mouse Embryonic Stem Cell Differentiation and May Guide Stem Cell FateTaylor-Weiner, Hermes et al. | 2012
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Interactions of the DNA Polymerase X From African Swine Fever Virus with the ssDNA. Properties of the Total DNA-Binding Site and the Strong DNA-Binding SubsiteJezewska, Maria J. et al. | 2012
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Deriving Transferable Parameters for the Coarse-Grained Martini Model: Application to Amyloid-Like and Elastin-Like PeptidesSeo, Mikyung et al. | 2012
-
Insight into the Mechanism of Hu-Induced DNA BendingMoreno, Andrew T. et al. | 2012
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Iron Ions Released from the Stainless-Steel Anode during High-Voltage Pulse Quench the Fluorescence of Calcein in both Solution and Electroporated CellsRodaitė-Riševičienė, Raminta et al. | 2012
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Network Topologies and Dynamics Leading to Endotoxin Tolerance and Priming in Innate Immune CellsFu, Yan et al. | 2012
-
Revealing Conformational Substates of Lipidated N-Ras Protein by Pressure ModulationKapoor, Shobhna et al. | 2012
-
Direct Observation of Plasma Membrane Domains using Super Resolution MicroscopyHarkes, Rolf et al. | 2012
-
Modulation Mechanism on the Conformational Diversities of Biantennary Complex-Type N-Glycans in WaterNishima, Wataru et al. | 2012
-
The Effects of Tension and Supercoiling on Protein-Mediated DNA LoopingDing, Yue et al. | 2012
-
Laurdan Fluorescence Lifetime as a Biosensor to Detect Differences and Changes in Membrane of Living CellsGolfetto, Ottavia et al. | 2012
-
The Longitudinal Correlation Length Controls the Range of Interactions Between DNA-Bending ProteinsZhang, Houyin et al. | 2012
-
Amphiphilic Effects of Chlorhexidine Digluconate on Rotational and Lateral Mobilities of Bacterial Outer and Model Membrane Lipid BilayersJang, Hye-Ock et al. | 2012
-
Effect of Lipid Bilayer Composition on the Membrane-Binding Ability and Depth of Insertion of Antimicrobial Piscidin 1: A Solid-State Deuterium NMR StudyShrestha, Akritee et al. | 2012
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Methods for Measuring Lipid Bilayer ViscosityHormel, Tristan T. et al. | 2012
-
Relating Molecular-Level Events with Bacterial Killing by Antimicrobial PeptidesMelo, Manuel N. et al. | 2012
-
Estimating the Free Energy to Bind a Potent Antimicrobial Lipopeptide to a Model Membrane BilayerLin, Dejun et al. | 2012
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Synergistic Insertion of Antimicrobial Peptides into MembranesStrandberg, Erik et al. | 2012
-
Optical Activation or Silencing of Neural Activaty in Neurons that Regulate Energy Balance in the HypothalamusYe, Chianping et al. | 2012
-
Changes of Intramolecular Distances in the Na+/K+ Atpase upon Ouabain BindingSanchez-Rodriguez, Jorge E. et al. | 2012
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Intercellular Calcium Waves in Vascular Smooth Muscle CellsQuijano, Jairo C. et al. | 2012
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Proton Tunneling Accelerates ATP Hydrolysis in Eg5 KinesinParke, Courtney et al. | 2012
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Interaction of Hydrophobic Surfactant Proteins with Oriented Phospholipid BilayersKumar, Kamlesh et al. | 2012
-
A Novel, Wafer-Level Method to Fabricate Zero-Mode Waveguides for Single Molecule DetectionLionberger, Troy A. et al. | 2012
-
Phosphoinositide Signaling Regulates the Surface Localization of the δ2 Ionotropic Glutamate ReceptorPetrou, Vasileios I. et al. | 2012
-
Effects of Epigallocatechin-3-Gallate on the Activation of Cardiac Thin Filaments by Calcium and Strong-Binding CrossbridgesFuchs, Franklin et al. | 2012
-
Temperature Behavior of Nanometer-Size Lipid Domains in DPPC:DLPC Model Membranes Studied by Small Angle Neutron ScatteringKrzyzanowski, Natalie et al. | 2012
-
Ultraviolet Resonance Raman Study of Lipid Mediated Peptide FoldingXiong, Jian et al. | 2012
-
Analysis of the Area Per Lipid in Protein-Membrane SystemsMori, Takaharu et al. | 2012
-
Adsorption and Rheological Properties of Myelin Basic Protein and Effects On the Interaction Forces Between Myelin BilayersLee, Dong Woog et al. | 2012
-
2H Solid-State NMR Studies of the Antimicrobial Peptide MSI-78 Interacting with the Membranes of Whole Escherichia ColiPius, James et al. | 2012
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Understanding Plasma Memebrane Organization and Cellular Homeostasis RelationshipSanchez, Susana et al. | 2012
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Identifying Motifs for Phosphatidylcholine Activation of Bacterial Phosphatidylinositol-Specific Phospholipase C EnzymesCheng, Jiongjia et al. | 2012
-
Allosteric Transition and Pharmacological Modulation of Pentameric Channel-Receptors: The Case of General AnestheticsCorringer, Pierre-Jean et al. | 2012
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Role of Surface Modifications in Ovalbumin Interacting with Lipid MembranesFraser, Andrew K. et al. | 2012
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Effect of Hydrophobic Peptide Sequence upon Peptide-Dependent Acceleration of Lipid Flip-FlopLeBarron, James et al. | 2012
-
Steps Towards a Modular Theory of DiseaseMarcotte, Edward M. et al. | 2012
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Intrinsic Heterogeneity in Liposome Suspensions Caused by the Dynamic Spontaneous Formation of Hydrophobic Active Sites in Lipid MembranesAgmo Hernandez, Victor et al. | 2012
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Impact of Aminoacylated Phospholipids on the Interactions of Antimicrobial Peptides with Phospholipid VesiclesPokorny, Antje et al. | 2012
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Antimicrobial Peptides: Correlation Between Pore Forming Potency in Lipid Vesicles and Antimicrobial, Hemolytic and Cytotoxic ActivityHe, Jing et al. | 2012
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Role of the Side Chains in the Activity of Cyclic N-Substituted Glycine OligomersKosutic, Marija et al. | 2012
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Regional Connexin43 De-Phosphorylation and AMP-Kinase Activation after Rapid Pacing in Myofilament Ca Sensitized HeartsBennuri, Sirish et al. | 2012
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A New Methodology for Quantitative LSPR BiosensingRaphael, Marc et al. | 2012
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Novel Na+-Selective Channels in the LysosomeWang, Xiang et al. | 2012
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Snake Venom-Derived Peptides as Tools for Intracellular DeliveryRodrigues, Margarida et al. | 2012
-
Molecular Dynamics Simulations of Cx26-Wt and Deafness Related Mutants M34A, A40G and V37IAraya-Secchi, Raul et al. | 2012
-
Cysteine Crosslinking to Study Allosteric Transitions of a Bacterial Homolog of Pentameric Channel-ReceptorsPrevost, Marie et al. | 2012
-
Molecular Mechanisms Governing Cx26/Cx32 Heterotypic Docking and Functional Gap Junction Channel FormationGong, Xiang-Qun et al. | 2012
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Properties of Two Cataract Associated Mutations Located in the N-Terminus of Connexin46Tong, Jun-Jie et al. | 2012
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Ser1928 is Required for Regulation of Calcium-Dependent Inactivation of CaV1.2 L-Type Calcium Channels by AKAP79-Anchored PKA and CalcineurinYoun, Dong-ho et al. | 2012
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Direct Observation of Catch-Bonds in Focal Adhesions of Living CellsBonakdar, Navid et al. | 2012
-
Filamin's Force Sensing Mechanism Revealed by Optical TweezersRognoni, Lorenz E. et al. | 2012
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A Novel FRET-Based Assay Reveals 1:1 Stoichiometry of Apocalmodulin Binding Across Voltage-Gated Ca and Na Ion ChannelsJohny, Manu B. et al. | 2012
-
Resolving the Grip of the Distal Carboxy Tail on the Proximal Calmodulatory Region of CaV ChannelsSang, Lingjie et al. | 2012
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Neutralizing the Charges in a Voltage Sensor Repairs Gating Perturbations in the Pore of CaV1.2Beyl, Stanislav et al. | 2012
-
Characterization of Cyclic Nucleotide Gated Channels using Atomic Force MicroscopeMaria Napolitano, Luisa et al. | 2012
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Integrated Structural Biology of the KCNQ1-KCNE3 ComplexVan Horn, Wade D. et al. | 2012
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Mathematical Model of Oxygen Labeling to Study Heart Energy TransferSchryer, David W. et al. | 2012
-
The Origins of Cross-Bridges in Active and Rigor Insect Flight Muscle are not as Predicted from Acto-S1 and X-Ray CrystallographyVargas, Claudia L. et al. | 2012
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Instability of the S1/S2 Hinge is not Affected by the Myosin FilamentHall, Nakiuda et al. | 2012
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Manganese Cation Reports on the Number of Coordinated Phosphates from the Nucleotide at the Active Site in Myosin ATPaseAstashkin, Andrei V. et al. | 2012
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Mapping the Structural Dynamics Within the Shaker Potassium Channel using Tethered Spectroscopic Probes as Chemical CalipersJarecki, Brian W. et al. | 2012
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KCNE1 Slows the Voltage Sensors of KCNQ1Ruscic, Katarina et al. | 2012
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Growth of Curved and Helical Bacterial CellsJiang, Hongyuan et al. | 2012
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NAADP is a Physiologically-Relevant Calcium Mobilising Compound in Atrial MyocytesBayliss, Rebecca A. et al. | 2012
-
Multiphase Recovery of Escherichia Coli to Hyperosmotic ShockPilizota, Teuta et al. | 2012
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The Role of the 2nd Threonine Within the TTVGYGD Sequence of Kv-Channels in C-Type Inactivation Gating, Ion Selectivity and PermeationLabro, Alain J. et al. | 2012
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Influence of Mecanical Stress on Tumor GrowthDelarue, Morgan et al. | 2012
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Structural Dynamics in Chloroplast Signal Recognition Particle (cpSRP) Proteins Studied with Single Molecule FluorescenceGao, Feng et al. | 2012
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Measurement of the Microscopic Dynamics of Photoprotection in Living Cells of Green AlgaeAmarnath, Kapil et al. | 2012
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Prediction of pKa Value of Zinc-Bound Water in Carbonic AnhydraseJiao, Dian et al. | 2012
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Organization and Dynamics of the Living E. Coli Nucleoid at High Resolution in Space and TimeFisher, Jay et al. | 2012
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Mechanical Stress on Double Stranded DNA Drives Homology RecognitionFeinstein, Efraim et al. | 2012
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MICU1 Serves as a Ca2+-Controlled Gatekeeper for the Mitochondrial Ca2+ UniporterCsordás, György et al. | 2012
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Modeling the Paradoxical Increase in Mitochondrial Calcium Buffering Power as Matrix Calcium IncreasesBazil, Jason N. et al. | 2012
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Retaining the Self Interactions in Alchemical Free Energy CalculationsMugnai, Mauro L. et al. | 2012
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Role of Polyhydroxybutyrate in Mitochondrial Calcium TransportSmithen, Matthew et al. | 2012
-
Protein Force Field Improved by using a New Backbone-Torsion-Energy TermSakae, Yoshitake et al. | 2012
-
Extended-System Adaptively Biased Simulations of Membrane Protein OrientationHénin, Jérôme et al. | 2012
-
Single Molecule Oxidative FoldingKosuri, Pallav et al. | 2012
-
Kinetic Schemes for Post-Synchronized Single Molecule DynamicsChen, Chunlai et al. | 2012
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Sub-Millisecond Single Molecule Fluorescence Imaging Combined with Dual Optical Tweezers on DNA TethersLlorente Garcia, Isabel et al. | 2012
-
Self-Assembly of a DNA-Based Switchable Linker for Single-Molecule Force SpectroscopyHalvorsen, Ken et al. | 2012
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Single-Molecule Elasticity Measurements Reveal Swelling Transition in PEG and Certain ssDNAsMcIntosh, Dustin B. et al. | 2012
-
High Bandwidth Resonant Radio Frequency Circuit for Lipid Bilayer DetectionBhat, Abhishek et al. | 2012
-
Conformational Change in the ATPase-Gate of Topoisomerase VI Induced by Nucleotide and DNALanz, Martin A. et al. | 2012
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Angular Morhpomechanics in the Establishment of Multicellular ArchitectureTanner, Kandice et al. | 2012
-
Photoswitchable Biocompatible Polymer Dots Doped with DiaryletheneOsakada, Yasuko et al. | 2012
-
Cellular Internalization and Degradation of Protein-Nanoparticle ComplexesFleischer, Candace C. et al. | 2012
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Electrophysiological Ion Channel Screening using Lipid BilayersSchmidt, Jacob et al. | 2012
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Measurements of Cell Mass Distribution during Cell Division with Quantitative Phase MicroscopyZangle, Thomas A. et al. | 2012
-
Novel Genetically Encoded Probes for Observing Molecular Processes in Living Cells by Two-Photon Polarization MicroscopyLazar, Josef et al. | 2012
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Three-Dimensional Real-Time Imaging of Gliding Motility in Apicomplexan Parasites using 4D Dark Field MicroscopyKelvin, James M. et al. | 2012
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Chondrocyte Deformation Under Extreme Tissue StrainsMadden, Ryan et al. | 2012
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Probing the Transport of Ionic Liquids in Aqueous Solution through NanoporesMahendran, Kozhinjampara R. et al. | 2012
-
Measurement of Average Transition-Path Time for Protein Folding in Single Molecule FRET ExperimentsSung Chung, Hoi et al. | 2012
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Cavities in the Hydrophobic Core Govern Pressure Unfolding of ProteinsRoche, Julien et al. | 2012
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Coordination of Multiple Motors Bound to Intracellular CargosHendricks, Adam G. et al. | 2012
-
Phasor Diagram Analysis of Telomeric G-Quadruplex Stability and HeterogeneityBuscaglia, Robert et al. | 2012
-
Transport Properties of a Prokaryotic CLC Transporter Assayed by Solid-Supported Membrane ElectrophysiologyGarcia-Celma, Juan J. et al. | 2012
-
The Simultaneous Determination of Diffusion Coefficients and PMFs Through the OFR MethodHolland, Bryan W. et al. | 2012
-
Separable Roles for ATPase Domains Involved in Virulence Factor SecretionBurton, Briana et al. | 2012
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Translational and Rotational Diffusion, and Conformational Dynamics of fd Virus on Freestanding Cationic Lipid MembranesHerold, Christoph et al. | 2012
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Ionization Properties of Phosphatidylinositol 4,5-Bisphosphate in Complex Ternary Lipid SystemsGraber, Zachary T. et al. | 2012
-
The Forces that Center the Mitotic SpindleHoward, Jonathon et al. | 2012
-
Live-Cell Super-Resolution Fluorescence Imaging at High Spatiotemporal ResolutionsShim, Sang-Hee et al. | 2012
-
2D/3D Super-Resolution Microscopy by Means of Individual Molecule Localization (IML) and Selective Plane Illumination MicroscopyCella Zanacchi, Francesca et al. | 2012
-
A DNA Lesion Alters the Global Conformational Dynamics of a Y-Family DNA Polymerase during CatalysisMaxwell, Brian A. et al. | 2012
-
Testing the Structural Mechanism of Transmembrane Translocation using De-Novo Designed Soft-Metal Transporters with Inverted Dual TopologyJoh, Nathan H. et al. | 2012
-
Three-Dimensional Structure of Full Length Integrin Embedded in MembraneXu, Xiao-Ping et al. | 2012
-
Remodeling of Actin Filaments by CofilinGalkin, Vitold E. et al. | 2012
-
Symmetry Breaking for Actin-Based Motility : From Molecular to MacroscopicCarvalho, Kevin et al. | 2012
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Regulation of Actin Isoforms by Nitric OxideBansbach, Heather M. et al. | 2012
-
Gamma Synuclein Forms Tertramers that can be Disrupted by Phospholipase CGolebiewska, Urszula P. et al. | 2012
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Inhibition of Lysozyme Amyloidogenesis by OsmolytesChandra, Nividh et al. | 2012
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The Interaction Between the Cell Membrane and Two Paddle DomainsUnnerståle, Sofia et al. | 2012
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Chloride Flux in Prestin-Expressing CellsZhong, Sheng et al. | 2012
-
Ligand Recognition of Lipocalin-Type Prostaglandin D SynthaseShimamoto, Shigeru et al. | 2012
-
In Vitro Folding of KvAP, a Voltage Gated K+ ChannelDevaraneni, Prasanna K. et al. | 2012
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Ubiquitin Dynamics in ComplexesPeters, Jan H. et al. | 2012
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Structural Differences Between Postsynaptic Densities Isolated from Different Brain RegionsBurgoyne, Madeline M. et al. | 2012
-
Thermal Melting of Duplex DNA in the Slow Exchange RegimeStellwagen, Earle et al. | 2012
-
Engineering Hyper-Catalytic Enzyme by Photo-Activated Conformation ModulationAgarwal, Pratul K. et al. | 2012
-
High-Bandwidth Magnetic Tweezers for Applying Torsion to Single DNA MoleculesJiang, Chang et al. | 2012
-
Testing Models For DNA Elasticity on Short Length Scales by Simulating DNA Supercoiling under TensionSchöpflin, Robert et al. | 2012
-
Nonlinear Elasticity of DNA BendingQu, Hao et al. | 2012
-
A Multi-State Mechanism of Nucleotide Selection in DNA Polymerase I Revealed by Single-Molecule FRETBerezhna, Svitlana et al. | 2012
-
Single Molecule FRET Characterization of Pre-mRNA Splicing: Substrate Dynamics during Recognition and CatalysisBlanco, Mario R. et al. | 2012
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Lipid Raft Formation and Properties are Necessary and Sufficient to Explain the Properties of Membrane Domains in B. Burgdorferi and are Necessary for its Membrane IntegrityLaRocca, Timothy J. et al. | 2012
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Interface Specificity of Phospholipase Activity using a Novel Surface Dilution Kinetic AssayRanganathan, Radha et al. | 2012
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RNA Polymerase II Translocation and Fidelity are Governed by Trigger Loop Dynamics: A Single-Molecule StudyZhou, Jing et al. | 2012
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Multiplexed Microfluidic Device for Bilayer Experimentation and Drug Screening Assays on Membrane ProteinsStimberg, Verena et al. | 2012
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Phase Separation in Model Membranes Controlled by Hybrid LipidsKumar Ghosh, Sajal et al. | 2012
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Probing the Organization and Dynamics of Lipid Probes in Phase Separated Supported Bilayers using Super-Resolution Fluorescence Localization MicroscopyKarslake, Jason et al. | 2012
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A Statistical Mechanical Model of Cholesterol/Phospholipid Mixtures: Linking Condensed Complexes, Superlattices, and the Phase DiagramSugar, Istvan P. et al. | 2012
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Role of Disorder in T-Cell SignalingWucherpfennig, Kai et al. | 2012
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In Vitro Characterization of a Novel N-Terminal CPVT RyR MutationNeco, Patricia et al. | 2012
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Effect of Ryanodine Receptor Refractoriness on the Induction of Calcium AlternansAlvarez-Lacalle, Enric et al. | 2012
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Molecular Dynamics Simulations of the Influenza Virus Envelope and Raft-Like Aggregates of HemagglutininParton, Daniel L. et al. | 2012
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Distribution, Orientation and Dynamics of 17β-Estradiol in Lipid Membranes Investigated by Solid-State NMRVogel, Alexander et al. | 2012
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Studying Calcium Signal Reshaping by Buffers Observing the Competition of Two DyesPiegari, Estefania et al. | 2012
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Altered Skeletal Muscle Excitation Contraction Coupling in DysferlinopathyZiman, Andrew P. et al. | 2012
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The C-Terminal Di-Arginine Motif of Cdc42 is Essential for Binding to Phosphatidylinositol 4,5 Bisphosphate-Containing Membranes and Inducing Cellular TransformationErickson, Jon et al. | 2012
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Sub-Frame Time Resolution in Fluorescence Imaging Reveals Delay Between SNAP25 Conformational change and Secretory Events in Chromaffin CellsZhao, Ying et al. | 2012
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Ranolazine Effects on NaV1.2 and Modulation by pHPeters, Colin H. et al. | 2012
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Action Potential-Triggered Somatic Exocytosis in Mesencephalic Trigeminal Nucleus Neurons in Rat Brain SlicesZhang, Bo et al. | 2012
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Ca2+ Dependent Inhibition of Cardiac Sodium ChannelDzhura, Igor et al. | 2012
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Drug Screening on Signal Transduction Proteins Via μ-Patterned SurfacesLanzerstorfer, Peter et al. | 2012
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Proton Block of the Pore Underlies the Loss of hERG Channel Conductance during AcidosisVan Slyke, Aaron et al. | 2012
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Rab27a Regulates Exocytosis of Large Dense-Core Granules in Mouse Chromaffin CellsHoerauf, Widmann W. et al. | 2012
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Unique Type of Sodium Channel Inhibition by RiluzoleMike, Arpad et al. | 2012
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TRPV4 Channels in Mouse Skeletal Muscle: Gene Expression, Role for Ca2+ Homeostasis and Muscle Force and FatigueLange, Thom et al. | 2012
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The Open Conformation of the Mg2+ Channel CorA from Solvent Accessibility and Distance ConstraintsSompornpisut, Pornthep et al. | 2012
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Polyhydroxybutyrate (PHB) is an Essential Structural Compound of TRPM8 Channel Required for its FunctionCao, Chike et al. | 2012
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Role of Central Cavity in Ion Permeation through the Kv1.2 ChannelSumikama, Takashi et al. | 2012
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SMD Simulations of a K+ Ion in the KcsA ChannelStefanovski, Darko et al. | 2012
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Multistep Electrical Remodeling and Sudden Death Precede Heart Failure in a Mouse Model of Inherited Dilated CardiomyopathyKurebayashi, Nagomi et al. | 2012
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A Universal Molecular Tension on a Single Integrin during Cell AdhesionWang, Xuefeng et al. | 2012
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The Geometry of Branching Actin Networks from Capping Branching and Filament GrowthSmith, Daniel B. et al. | 2012
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Structure of Titin PEVK Explored with FRET SpectroscopyHuber, Tamas et al. | 2012
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FRET Reveals Substantial Reorientation of the Cytoplasmic Interface of the Skeletal Muscle DHPR in the Presence of RyR1Polster, Alexander et al. | 2012
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Incorporating Cooperativity into Huxley-Type Cross-Bridge Models in Thermodynamically Consistent WayKalda, Mari et al. | 2012
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Symmetric Modulation of Cross-Bridge Kinetics by Sarcomere Velocity during Shortening and Lengthening in Cardiac Trabeculae; A New Insight on Sarcomere DynamicsYadid, Moran et al. | 2012
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Changes in the Myocardial Expression of Tropomyosin Isoforms Modulate Troponin T-Mediated Cardiac Thin Filament ActivationMamidi, Ranganath et al. | 2012
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Cross-Bridge Cycling Kinetics in Intact Multicellular Cardiac Muscle at Physiological Temperature: Impact of Muscle LengthMilani-Nejad, Nima et al. | 2012
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Mechanism of Doxorubicin-Induced Suppression of Cardiac Ankyrin Repeat Protein: Implications for Anthracycline CardiomyopathyZhong, Lin et al. | 2012
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Transmural Heterogeneity and Depressed Function in the Mechanical Properties of Ventricular Tissue from Patients with End-Stage Heart FailureShekar, Premi et al. | 2012
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Simulation of Myoplasmic Calcium Transients in Mouse Slow-Twitch Muscle FibersBaylor, Stephen M. et al. | 2012
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Heart of the Matter: Assessing Human Cardiomyopathies with Spontaneous Oscillatory Contractions (SPOC)Li, Amy et al. | 2012
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Mapping Vesicle Trafficking during Plant Cell Cytokinesis using Spatio-Temporal Image Correlation SpectroscopyGuillet, Dominique et al. | 2012
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Specific Ion Efects on Actin Filament Stability and Flexural RigidityKang, Hyeran et al. | 2012
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Molecular Dynamics Analysis of Coupling Behaviors Between Extension and Torsion of Actin FilamentsMatsushita, Shinji et al. | 2012
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Modeling and Simulation of Myosin-Dependent Rearrangement and Force Generation in an Actomyosin NetworkInoue, Yasuhiro et al. | 2012
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Regulation of Axonal Transport by Kinesin Phosphorylation at S176Thompson, Andrew R. et al. | 2012
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Dynamic Self-Organization of Bacterial DNA Segregation Machinery in a Cell-Free ReactionChin Hwang, Ling et al. | 2012
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Incorporation of Photochromic Molecule into the Functional Loop L5 of Kinesin for the Purpose of Photo-RegulationIshikawa, Kumiko et al. | 2012
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Structural Studies of Septin2G Amyloid FibrilsItri, Rosangela et al. | 2012
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Characterization of the Microtubules Modified with Photochromic MoleculesIshiyama, Koichiro et al. | 2012
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Temperature Dependent Dynamics of Cytochrome P450cam from Elastic Incoherent Neutron ScatteringYi, Zheng et al. | 2012
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Corral Trapping of Single Molecules in Solution: Theory and ApplicationsCarlson, Christine A. et al. | 2012
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Networks of Dynein and Regulatory Proteins in Flagella/Cilia Visualized by Electron Cryo-TomographyIshikawa, Takashi et al. | 2012
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Structural Investigation of Molecular Components of T. Brucei Flagellum by Cryo Electron TomographyKoyfman, Alexey Y. et al. | 2012
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Three Dimensional Imaging of Maurer's Clefts in “Unroofed”Plasmodium Falciparum-Infected Erythrocytes by Transmission Electron MicroscopyHayakawa, Eri H. et al. | 2012
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Engineered Dynein Mutants Reveal Minimal Structural and Catalytic Requirements for Processive MotilityCleary, Frank B. et al. | 2012
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Gating Ion Translocation through the Na,K-ATPase PumpVedovato, Natascia et al. | 2012
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Flexural Rigidity and Shear Stiffness of FlagellaXu, Gang et al. | 2012
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Structure of Trypanosoma Brucei Flagellum Accounts for its Bihelical MotionSchmid, Michael F. et al. | 2012
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Decreased Fatigue Resistance is an Early Functional Defect in Skeletal Muscles of Mitochondrial-DNA-Mutator MiceWesterblad, Håkan et al. | 2012
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Action Mechanism of ODPC in Giants Unilamellar Vesicles as Observed by Optical MicroscopyBarbosa Gomide, Andreza et al. | 2012
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Discovery of VEGF-KDR Binding Inhibitors by Screening Small-Molecule Microarrays with Label-Free Ellipsometric ScannersLandry, James P. et al. | 2012
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MloK1 Ligand Binding Simulations Indicate an Induced-Fit MechanismVoß, Béla et al. | 2012