5-Benzothiazole substituted pyrimidine derivatives as HCV replication (replicase) inhibitors (English)
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In:
Bioorganic & medicinal chemistry letters
;
22
, 9
; 3229-3235
;
2012
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ISSN:
- Article (Journal) / Print
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Title:5-Benzothiazole substituted pyrimidine derivatives as HCV replication (replicase) inhibitors
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Contributors:Arasappan, Ashok ( author ) / Bennett, Frank / Girijavallabhan, Vinay / Huang, Yuhua / Huelgas, Regina / Alvarez, Carmen / Chen, Lei / Gavalas, Stephen / Kim, Seong-Heon / Kosinski, Aneta
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Published in:Bioorganic & medicinal chemistry letters ; 22, 9 ; 3229-3235
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Publisher:
- New search for: Elsevier
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Place of publication:Amsterdam [u.a.]
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Publication date:2012
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ISSN:
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ZDBID:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 35.70 / 44.33 / 44.42
- Further information on Basic classification
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Keywords:
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Classification:
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Source:
Table of contents – Volume 22, Issue 9
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 3021
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Graphical contents list| 2012
- 3039
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Design, synthesis, and biological evaluation of chalcone oxime derivatives as potential immunosuppressive agentsLuo, Yin / Song, Ran / Li, Yao / Zhang, Shuai / Liu, Zhi-Jun / Fu, Jie / Zhu, Hai-Liang et al. | 2012
- 3044
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Preparation, antibacterial evaluation and preliminary structure–activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivativesOuyang, Liang / Huang, Yuhui / Zhao, Yuwei / He, Gu / Xie, Yongmei / Liu, Jie / He, Jun / Liu, Bo / Wei, Yuquan et al. | 2012
- 3050
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Discovery of new quinoline ether inhibitors with high affinity and selectivity for PDGFR tyrosine kinasesPlé, Patrick A. / Jung, Frédéric / Ashton, Sue / Hennequin, Laurent / Laine, Romuald / Lambert-van der Brempt, Christine / Morgentin, Rémy / Pasquet, Georges / Taylor, Sian et al. | 2012
- 3056
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Design, synthesis and structure–activity-relationship of 1,5-tetrahydronaphthyridines as CETP inhibitorsFernandez, Maria-Carmen / Escribano, Ana / Mateo, Ana I. / Parthasarathy, Saravanan / Martin de la Nava, Eva M. / Wang, Xiaodong / Cockerham, Sandra L. / Beyer, Thomas P. / Schmidt, Robert J. / Cao, Guoqing et al. | 2012
- 3063
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Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarinsBalboni, Gianfranco / Congiu, Cenzo / Onnis, Valentina / Maresca, Alfonso / Scozzafava, Andrea / Winum, Jean-Yves / Maietti, Annalisa / Supuran, Claudiu T. et al. | 2012
- 3067
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Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activitiesChang, Minsun / Lee, Sung-Hak / Kim, Ho Jun / Koh, Jong-Sung / Kim, Aeri et al. | 2012
- 3072
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Design, synthesis and anticonvulsant activities of novel 1-(substituted/unsubstituted benzylidene)-4-(4-(6,8-dibromo-2-(methyl/phenyl)-4-oxoquinazolin-3(4H)-yl)phenyl) semicarbazide derivativesSaravanan, Govindaraj / Alagarsamy, Veerachamy / Prakash, Chinnasamy Rajaram et al. | 2012
- 3079
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Development of rationally designed DNA N6 adenine methyltransferase inhibitorsHobley, Gerard / McKelvie, Jennifer C. / Harmer, Jenny E. / Howe, Jason / Oyston, Petra C.F. / Roach, Peter L. et al. | 2012
- 3083
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Synthesis and SAR of 1,3-thiazolyl thiophene and pyridine derivatives as potent, orally active and S1P3-sparing S1P1 agonistsAsano, Masayoshi / Nakamura, Tsuyoshi / Sekiguchi, Yukiko / Mizuno, Yumiko / Yamaguchi, Takahiro / Tamaki, Kazuhiko / Shimozato, Takaichi / Doi-Komuro, Hiromi / Kagari, Takashi / Tomisato, Wataru et al. | 2012
- 3089
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Inhibition of quorum sensing regulated biofilm formation in Serratia marcescens causing nosocomial infectionsBakkiyaraj, Dhamodharan / Sivasankar, Chandran / Pandian, Shunmugiah Karutha et al. | 2012
- 3095
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Quinolinyl- and phenantridinyl-acetamides as bradykinin B1 receptor antagonistsÉles, János / Beke, Gyula / Vágó, István / Bozó, Éva / Huszár, József / Tarcsay, Ákos / Kolok, Sándor / Schmidt, Éva / Vastag, Mónika / Hornok, Katalin et al. | 2012
- 3100
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Efficient synthesis of Guanfu base G via highly regioselective lipase-catalyzed acylation in non-aqueous phaseXia, Ye / Liu, Ji-Hua / Liu, Jing-Han / Yu, Bo-Yang et al. | 2012
- 3104
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Synthesis, characterization, molecular docking and cytotoxic activity of novel plumbagin hydrazones against breast cancer cellsDandawate, Prasad / Khan, Ejazuddin / Padhye, Subhash / Gaba, Himanshi / Sinha, Swati / Deshpande, Jyoti / Venkateswara Swamy, K. / Khetmalas, Madhukar / Ahmad, Aamir / Sarkar, Fazlul H. et al. | 2012
- 3109
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Discovery of small molecule HIV-1 integrase dimerization inhibitorsTintori, Cristina / Demeulemeester, Jonas / Franchi, Luigi / Massa, Silvio / Debyser, Zeger / Christ, Frauke / Botta, Maurizio et al. | 2012
- 3115
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Synthesis and evaluation of anti-thrombotic activity of benzocoumarin amide derivativesSashidhara, Koneni V. / Palnati, Gopala Reddy / Avula, Srinivasa Rao / Singh, Surendra / Jain, Manish / Dikshit, Madhu et al. | 2012
- 3122
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Synthesis and evaluation of 2-[2-(phenylthiomethyl)-1H-benzo[d] imidazol-1-yl)acetohydrazide derivatives as antitumor agentsLiu, Ting / Sun, Changyan / Xing, Xiumei / Jing, Lingling / Tan, Rui / Luo, Youfu / Huang, Wencai / Song, Hang / Li, Zicheng / Zhao, Yinglan et al. | 2012
- 3126
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Cytotoxic cytochalasins from the endozoic fungus Phoma sp. of the giant jellyfish Nemopilema nomuraiKim, Eun La / Li, Jian Lin / Dang, Hung The / Hong, Jongki / Lee, Chong-Ok / Kim, Dong-Kyoo / Yoon, Won Duk / Kim, Euikyung / Liu, Yonghong / Jung, Jee H. et al. | 2012
- 3130
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Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonistEpifano, Francesco / Genovese, Salvatore / James Squires, E. / Gray, Matthew A. et al. | 2012
- 3136
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Enzymatic synthesis of 8-vinyl- and 8-styryl-2prime-deoxyguanosine modified DNA-novel fluorescent molecular probesHolzberger, B. / Strohmeier, J. / Siegmund, V. / Diederichsen, U. / Marx, A. et al. | 2012
- 3136
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Enzymatic synthesis of 8-vinyl- and 8-styryl-2′-deoxyguanosine modified DNA—novel fluorescent molecular probesHolzberger, Bastian / Strohmeier, Julian / Siegmund, Vanessa / Diederichsen, Ulf / Marx, Andreas et al. | 2012
- 3140
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Triazoloamides as potent γ-secretase modulators with reduced hERG liabilityFischer, Christian / Zultanski, Susan L. / Zhou, Hua / Methot, Joey L. / Shah, Sanjiv / Nuthall, Hugh / Hughes, Bethany L. / Smotrov, Nadja / Hill, Armetta / Szewczak, Alexander A. et al. | 2012
- 3140
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Triazoloamides as potent g-secretase modulators with reduced hERG liabilityFischer, C. / Zultanski, S. L. / Zhou, H. / Methot, J. L. / Shah, S. / Nuthall, H. / Hughes, B. L. / Smotrov, N. / Hill, A. / Szewczak, A. A. et al. | 2012
- 3147
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An approach for differentiating isozymes. Construction of libraries containing short aromatic peptides as part of a method to design selective inhibitors against lipasesPark, Sangeun / Yu, Jaehoon et al. | 2012
- 3152
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The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistryHuang, Baohua / Kukowska-Latallo, Jolanta F. / Tang, Shengzhuang / Zong, Hong / Johnson, Kali B. / Desai, Ankur / Gordon, Chris L. / Leroueil, Pascale R. / Baker, James R. Jr. et al. | 2012
- 3157
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Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonistsSasmal, Sanjita / Balaji, Gade / Kanna Reddy, Hariprasada R. / Balasubrahmanyam, D. / Srinivas, Gujjary / Kyasa, ShivaKumar / Sasmal, Pradip K. / Khanna, Ish / Talwar, Rashmi / Suresh, J. et al. | 2012
- 3163
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Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists: Part 2Sasmal, Sanjita / Balasubrahmanyam, D. / Kanna Reddy, Hariprasada R. / Balaji, Gade / Srinivas, Gujjary / Cheera, Srisailam / Abbineni, Chandrasekhar / Sasmal, Pradip K. / Khanna, Ish / Sebastian, V.J. et al. | 2012
- 3168
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Glucose–aspirin: Synthesis and in vitro anti-cancer activity studiesJacob, James N. / Tazawa, Makio J. et al. | 2012
- 3172
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Synthesis and characterization of pyruvate–isoniazid analogs and their copper complexes as potential ICL inhibitorsShingnapurkar, Dipti / Dandawate, Prasad / Anson, Christopher E. / Powell, Annie K. / Afrasiabi, Zahra / Sinn, Ekkehard / Pandit, Shital / Venkateswara Swamy, K. / Franzblau, Scott / Padhye, Subhash et al. | 2012
- 3177
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The effects of diketopiperazines from Callyspongia sp. on release of cytokines and chemokines in cultured J774A.1 macrophagesChen, Jin-Hui / Lan, Xiang-Peng / Liu, Yonghong / Jia, Ai-Qun et al. | 2012
- 3181
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Discovery of a novel acetylcholinesterase inhibitor by structure-based virtual screening techniquesChen, Yao / Fang, Lei / Peng, Sixun / Liao, Hong / Lehmann, Jochen / Zhang, Yihua et al. | 2012
- 3188
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Pyronepolyene C-glucosides with NF-κB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp. JJY40Peng, Jixing / Jiao, Jieying / Li, Jing / Wang, Wei / Gu, Qianqun / Zhu, Tianjiao / Li, Dehai et al. | 2012
- 3188
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Pyronepolyene C-glucosides with NF-kB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp. JJY40Peng, J. / Jiao, J. / Li, J. / Wang, W. / Gu, Q. / Zhu, T. / Li, D. et al. | 2012
- 3191
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Synthesis and antitumor-evaluation of 1,3,4-thiadiazole-containing benzisoselenazolone derivativesLuo, Zhenhua / Chen, Baoquan / He, Shuangyan / Shi, Yanping / Liu, Yuming / Li, Caiwen et al. | 2012
- 3194
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3D-QSAR Study on dihydro-1,3,5-triazines and their spiro derivatives as DHFR inhibitors by comparative molecular field analysis (CoMFA)Ma, Xiang / Xiang, Guangya / Yap, Chun-Wei / Chui, Wai-Keung et al. | 2012
- 3198
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Synthesis and structure–activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent β isoform selective phosphatidylinositol 3-kinase inhibitorsSanchez, Robert M. / Erhard, Karl / Hardwicke, Mary Ann / Lin, Hong / McSurdy-Freed, Jeanelle / Plant, Ramona / Raha, Kaushik / Rominger, Cynthia M. / Schaber, Michael D. / Spengler, Michael D. et al. | 2012
- 3198
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Synthesis and structure-activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent b isoform selective phosphatidylinositol 3-kinase inhibitorsSanchez, R. M. / Erhard, K. / Hardwicke, M. A. / Lin, H. / McSurdy-Freed, J. / Plant, R. / Raha, K. / Rominger, C. M. / Schaber, M. D. / Spengler, M. D. et al. | 2012
- 3203
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Lead optimization of 4,4-biaryl piperidine amides as γ-secretase inhibitorsClose, Joshua / Heidebrecht, Richard Jr. / Hendrix, John / Li, Chaomin / Munoz, Ben / Surdi, Laura / Kattar, Solomon / Tempest, Paul / Moses, Paul / Geng, Xiaoliu et al. | 2012
- 3203
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Lead optimization of 4,4-biaryl piperidine amides as g-secretase inhibitorsClose, J. / Heidebrecht, R. / Hendrix, J. / Li, C. / Munoz, B. / Surdi, L. / Kattar, S. / Tempest, P. / Moses, P. / Geng, X. et al. | 2012
- 3208
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Thienopyridine ureas as dual inhibitors of the VEGF and Aurora kinase familiesCurtin, Michael L. / Frey, Robin R. / Heyman, H. Robin / Soni, Niru B. / Marcotte, Patrick A. / Pease, Lori J. / Glaser, Keith B. / Magoc, Terrance J. / Tapang, Paul / Albert, Daniel H. et al. | 2012
- 3213
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Development of hydrocortisone succinic acid/and 5-fluorouracil/chitosan microcapsules for oral and topical drug deliveriesLam, Pik-Ling / Lee, Kenneth Ka-Ho / Wong, Raymond Siu-Ming / Cheng, Gregory Yin Ming / Cheng, Shuk Yan / Yuen, Marcus Chun-Wah / Lam, Kim-Hung / Gambari, Roberto / Kok, Stanton Hon-Lung / Chui, Chung-Hin et al. | 2012
- 3219
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Anti-AIDS agents 89. Identification of DCX derivatives as anti-HIV and chemosensitizing dual function agents to overcome P-gp-mediated drug resistance for AIDS therapyZhou, Ting / Ohkoshi, Emika / Shi, Qian / Bastow, Kenneth F. / Lee, Kuo-Hsiung et al. | 2012
- 3223
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Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluationBanerjee, Abhisek / Yadav, Pravin S. / Bajpai, Malini / Sangana, Ramachandra Rao / Gullapalli, Srinivas / Gudi, Girish S. / Gharat, Laxmikant A. et al. | 2012
- 3229
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5-Benzothiazole substituted pyrimidine derivatives as HCV replication (replicase) inhibitorsArasappan, Ashok / Bennett, Frank / Girijavallabhan, Vinay / Huang, Yuhua / Huelgas, Regina / Alvarez, Carmen / Chen, Lei / Gavalas, Stephen / Kim, Seong-Heon / Kosinski, Aneta et al. | 2012
- 3235
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4-(1-Phenyl-1H-pyrazol-4-yl)quinolines as novel, selective and brain penetrant metabotropic glutamate receptor 4 positive allosteric modulatorsJimenez, Hermogenes N. / Liu, Kevin G. / Hong, Sang-Phyo / Reitman, Michael S. / Uberti, Michelle A. / Bacolod, Maria D. / Cajina, Manuel / Nattini, Megan / Sabio, Michael / Doller, Darío et al. | 2012
- 3240
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A conformationally restricted uniconazole analogue as a specific inhibitor of rice ent-kaurene oxidase, CYP701A6Todoroki, Yasushi / Naiki, Kumi / Muramatsu, Taku / Ohnishi, Toshiyuki / Ueno, Kotomi / Mizutani, Masaharu / Hirai, Nobuhiro et al. | 2012
- 3244
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Analogs of the RSK inhibitor SL0101: Optimization of in vitro biological stabilityHilinski, Michael K. / Mrozowski, Roman M. / Clark, David E. / Lannigan, Deborah A. et al. | 2012
- 3248
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Conformationally restricted novel pyrazole derivatives: Synthesis of 1,8-disubstituted 5,5-dimethyl-4,5-dihydro-1H-benzo[g]indazoles as a new class of PDE4 inhibitorsShyamsunder Reddy, T. / Shiva Kumar, K. / Meda, Chandana L.T. / Kandale, Ajit / Rambabu, D. / Rama Krishna, G. / Hariprasad, C. / Venugopala Rao, V. / Venkataiah, S. / Malla Reddy, C. et al. | 2012
- 3256
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Novel acridinedione derivatives: Design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studiesAlvala, Mallika / Bhatnagar, Shubhmita / Ravi, Alvala / Jeankumar, Variam Ullas / Manjashetty, Thimmappa H / Yogeeswari, Perumal / Sriram, Dharmarajan et al. | 2012
- 3261
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Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitorChen, Shang-Ke / Zhao, Peng / Shao, Yong-Xian / Li, Zhe / Zhang, Cuixian / Liu, Peiqing / He, Xixin / Luo, Hai-Bin / Hu, Xiaopeng et al. | 2012
- 3265
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Discovery of 4prime-azido-2prime-deoxy-2prime-C-methyl cytidine and prodrugs thereof: A potent inhibitor of Hepatitis C virus replicationNilsson, M. / Kalayanov, G. / Winqvist, A. / Pinho, P. / Sund, C. / Zhou, X. X. / Wahling, H. / Belfrage, A. K. / Pelcman, M. / Agback, T. et al. | 2012
- 3265
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Discovery of 4′-azido-2′-deoxy-2′-C-methyl cytidine and prodrugs thereof: A potent inhibitor of Hepatitis C virus replicationNilsson, Magnus / Kalayanov, Genadiy / Winqvist, Anna / Pinho, Pedro / Sund, Christian / Zhou, Xiao-Xiong / Wähling, Horst / Belfrage, Anna-Karin / Pelcman, Michael / Agback, Tatiana et al. | 2012
- 3269
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New diarylureas and diarylamides possessing acet(benz)amidophenyl scaffold: Design, synthesis, and antiproliferative activity against melanoma cell lineKim, Hee Jin / Cho, Hye Jung / Kim, Hwan / El-Gamal, Mohammed I. / Oh, Chang-Hyun / Lee, So Ha / Sim, Taebo / Hah, Jung-Mi / Yoo, Kyung Ho et al. | 2012
- 3274
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Design, synthesis, molecular docking and biological evaluation of new dithiocarbamates substituted benzimidazole and chalcones as possible chemotherapeutic agentsBacharaju, Keerthana / Jambula, Swathi Reddy / Sivan, Sreekanth / JyostnaTangeda, Saritha / Manga, Vijjulatha et al. | 2012
- 3278
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In silico binding free energy predictability with π–π interaction energy-augmented scoring function: Benzimidazole Raf inhibitors as a case studyChung, Jae Yoon / Cho, Seung Joo / Cho, Art E. / Hah, Jung-Mi et al. | 2012
- 3278
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In silico binding free energy predictability with p-p interaction energy-augmented scoring function: Benzimidazole Raf inhibitors as a case studyChung, J. Y. / Cho, S. J. / Cho, A. E. / Hah, J. M. et al. | 2012
- 3284
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Design, synthesis, and biological activity of novel 1,4-disubstituted piperidine/piperazine derivatives as CCR5 antagonist-based HIV-1 entry inhibitorsDong, Ming-xin / Lu, Lu / Li, Haitao / Wang, Xiaohua / Lu, Hong / Jiang, Shibo / Dai, Qiu-yun et al. | 2012
- 3287
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An Hsp90 modulator that exhibits a unique mechanistic profileRamsey, Deborah M. / McConnell, Jeanette R. / Alexander, Leslie D. / Tanaka, Kaishin W. / Vera, Chester M. / McAlpine, Shelli R. et al. | 2012
- 3291
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Steroidal C-21 heteroaryl thioethers. Part 3: Pregn-4-eno-[3,2-c]pyrazole fused A ring modified steroids as selective glucocorticoid receptor modulators (dissociated steroids)Biju, Purakkattle / Wang, Hongwu / Anthes, John / McCormick, Kevin / Aslanian, Robert / Berlin, Michael / Bitar, Rema / Lim, Yeon-Hee / Lee, Yoon Joo / Prelusky, Daniel et al. | 2012
- 3296
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X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinaseMcLean, Larry R. / Zhang, Ying / Zaidi, Nisha / Bi, Xiping / Wang, Rachel / Dharanipragada, Ram / Jurcak, John G. / Gillespy, Timothy A. / Zhao, Zhicheng / Musick, Kwon Y. et al. | 2012
- 3301
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Design and synthesis of carbamate and thiocarbamate derivatives and their inhibitory activities of NO production in LPS activated macrophagesJin, Guo Hua / Lee, Hwa Jin / Gim, Hyo Jin / Ryu, Jae-Ha / Jeon, Raok et al. | 2012
- 3305
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Isoquinoline derivatives as potent CRTH2 receptor antagonists: Synthesis and SARNishikawa-Shimono, Rie / Sekiguchi, Yoshinori / Koami, Takeshi / Kawamura, Madoka / Wakasugi, Daisuke / Watanabe, Kazuhito / Wakahara, Shunichi / Matsumoto, Kayo / Takayama, Tetsuo et al. | 2012
- 3311
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Discovery of an orally-bioavailable CC Chemokine Receptor 2 antagonist derived from an acyclic diaminoalcohol backboneCarter, Percy H. / Brown, Gregory D. / King, Sarah R. / Voss, Matthew E. / Tebben, Andrew J. / Cherney, Robert J. / Mandlekar, Sandhya / Lo, Yvonne C. / Yang, Gengjie / Miller, Persymphonie B. et al. | 2012
- 3317
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Fluoride enhances the activity of fungicides that destabilize cell membranesLi, Sanshu / Breaker, Ronald R. et al. | 2012
- 3323
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Inhibition of platelet adhesion by peptidomimetics mimicking the interactive b-hairpin of glycoprotein IbaBernard, E. / Buckley, V. / Moman, E. / Coleman, L. / Meade, G. / Kenny, D. / Devocelle, M. et al. | 2012
- 3323
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Inhibition of platelet adhesion by peptidomimetics mimicking the interactive β-hairpin of glycoprotein IbαBernard, Elise / Buckley, Vivienne / Moman, Edelmiro / Coleman, Lorraine / Meade, Gerardene / Kenny, Dermot / Devocelle, Marc et al. | 2012
- 3327
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Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cellsPierre, Fabrice / Regan, Collin F. / Chevrel, Marie-Claire / Siddiqui-Jain, Adam / Macalino, Diwata / Streiner, Nicole / Drygin, Denis / Haddach, Mustapha / O’Brien, Sean E. / Rice, William G. et al. | 2012
- 3332
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Penicacids A–C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07Chen, Ziming / Zheng, Zhihui / Huang, Hongbo / Song, Yongxiang / Zhang, Xuelian / Ma, Junying / Wang, Bo / Zhang, Changsheng / Ju, Jianhua et al. | 2012
- 3336
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Quantitative structure and bioactivity relationship study on human acetylcholinesterase inhibitorsYan, Aixia / Wang, Kai et al. | 2012
- 3343
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Synthesis and inhibitory effect of piperine derivates on monoamine oxidaseMu, Li-Hua / Wang, Bo / Ren, Hao-Yang / Liu, Ping / Guo, Dai-Hong / Wang, Fu-Meng / Bai, Lin / Guo, Yan-Shen et al. | 2012
- 3349
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Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosisChapman, Timothy M. / Bouloc, Nathalie / Buxton, Roger S. / Chugh, Jasveen / Lougheed, Kathryn E.A. / Osborne, Simon A. / Saxty, Barbara / Smerdon, Stephen J. / Taylor, Debra L. / Whalley, David et al. | 2012
- 3354
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Fused bicycles as arylketone bioisosteres leading to potent, orally active thiadiazole H3 antagonistsXiao, Dong / Palani, Anandan / Sofolarides, Michael / Aslanian, Robert / West, Robert E. Jr. / Williams, Shirley M. / Wu, Ren-Long / Hwa, Joyce / Sondey, Christopher / Lachowicz, Jean et al. | 2012
- 3358
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Blocking HIV-1 entry by a gp120 surface binding inhibitorTsou, Lun K. / Chen, Chin-Ho / Dutschman, Ginger E. / Cheng, Yung-Chi / Hamilton, Andrew D. et al. | 2012
- 3362
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Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indolesYoungsaye, Willmen / Dockendorff, Chris / Vincent, Benjamin / Hartland, Cathy L. / Bittker, Joshua A. / Dandapani, Sivaraman / Palmer, Michelle / Whitesell, Luke / Lindquist, Susan / Schreiber, Stuart L. et al. | 2012
- 3366
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Design, synthesis and structure–activity relationship of N-substituted tropane muscarinic acetylcholine receptor antagonistsLainé, Dramane I. / Yan, Hongxing / Xie, Haibo / Davis, Roderick S. / Dufour, Jeremy / Widdowson, Katherine L. / Palovich, Michael R. / Wan, Zehong / Foley, James J. / Schmidt, Dulcie B. et al. | 2012
- 3370
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Dimerization of β-tryptase inhibitors, does it work for both basic and neutral P1 groups?Liang, Guyan / Choi-Sledeski, Yong Mi / Chen, Xin / Gong, Yong / MacMillan, Eric W. / Tsay, Joseph / Sides, Keith / Cairns, Jennifer / Kulitzscher, Berndt / Aldous, David J. et al. | 2012
- 3370
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Dimerization of b-tryptase inhibitors, does it work for both basic and neutral P1 groups?Liang, G. / Choi-Sledeski, Y. M. / Chen, X. / Gong, Y. / MacMillan, E. W. / Tsay, J. / Sides, K. / Cairns, J. / Kulitzscher, B. / Aldous, D. J. et al. | 2012
- IFC
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Editorial board| 2012