S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: Potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,d-arabinofuranosyl)adenine (English)
- New search for: Shokar, Ajit
- New search for: Shokar, Ajit
- New search for: Au, Aaron
- New search for: An, Seung Hwan
- New search for: Tong, Elsie
- New search for: Garza, Gabriel
- New search for: Zayas, Jessica
- New search for: Wnuk, Stanislaw F.
- New search for: Land, Kirkwood M.
In:
Bioorganic & medicinal chemistry letters
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22
, 12
; 4203-4206
;
2012
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ISSN:
- Article (Journal) / Print
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Title:S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: Potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,d-arabinofuranosyl)adenine
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Contributors:Shokar, Ajit ( author ) / Au, Aaron / An, Seung Hwan / Tong, Elsie / Garza, Gabriel / Zayas, Jessica / Wnuk, Stanislaw F. / Land, Kirkwood M.
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Published in:Bioorganic & medicinal chemistry letters ; 22, 12 ; 4203-4206
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Publisher:
- New search for: Elsevier
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Place of publication:Amsterdam [u.a.]
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Publication date:2012
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ISSN:
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ZDBID:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 35.70 / 44.33 / 44.42
- Further information on Basic classification
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Keywords:
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Source:
Table of contents – Volume 22, Issue 12
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 3843
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Graphical contents list| 2012
- 3862
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Thiourea compound AW00178 sensitizes human H1299 lung carcinoma cells to TRAIL-mediated apoptosisRyu, Byung Jun / Hwang, Mi-Kyung / Park, Mikyung / Lee, Kyunghee / Kim, Seong Hwan et al. | 2012
- 3866
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Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptidesWollinsky, Beate / Ludwig, Lena / Hamacher, Alexandra / Yu, Xia / Kassack, Matthias U. / Li, Shu-Ming et al. | 2012
- 3870
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Production of truncated protein by the crosslink formation of mRNA with 2′-OMe oligoribonucleotide containing 2-amino-6-vinylpurineHagihara, Shinya / Kusano, Shuhei / Lin, Wei-Chen / Chao, Xiao-guang / Hori, Tsuneaki / Imoto, Shuhei / Nagatsugi, Fumi et al. | 2012
- 3870
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Production of truncated protein by the crosslink formation of mRNA with 2prime-OMe oligoribonucleotide containing 2-amino-6-vinylpurineHagihara, S. / Kusano, S. / Lin, W. C. / Chao, X. g. / Hori, T. / Imoto, S. / Nagatsugi, F. et al. | 2012
- 3873
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Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetesMcCoull, William / Addie, Matthew S. / Birch, Alan M. / Birtles, Susan / Buckett, Linda K. / Butlin, Roger J. / Bowker, Suzanne S. / Boyd, Scott / Chapman, Stephen / Davies, Robert D.M. et al. | 2012
- 3879
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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseasesBrown, Dearg S. / Cumming, John G. / Bethel, Paul / Finlayson, Jonathan / Gerhardt, Stefan / Nash, Ian / Pauptit, Richard A. / Pike, Kurt G. / Reid, Alan / Snelson, Wendy et al. | 2012
- 3879
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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38a MAP kinase inhibitor for the treatment of inflammatory diseasesBrown, D. S. / Cumming, J. G. / Bethel, P. / Finlayson, J. / Gerhardt, S. / Nash, I. / Pauptit, R. A. / Pike, K. G. / Reid, A. / Snelson, W. et al. | 2012
- 3884
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N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetrationWei, Zhongyong / Yang, Hua / Liu, Ziping / Tremblay, Maxime / Johnstone, Shawn / Béha, Sara / Yue, Shi Yi / Srivastava, Sanjay / Tomaszewski, Miroslaw J. / Brown, William et al. | 2012
- 3890
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Disubstituted piperidines as potent orexin (hypocretin) receptor antagonistsJiang, Rong / Song, Xinyi / Bali, Purva / Smith, Anthony / Bayona, Claudia Ruiz / Lin, Li / Cameron, Michael D. / McDonald, Patricia H. / Kenny, Paul J. / Kamenecka, Theodore M. et al. | 2012
- 3895
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The design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivityCumming, John G. / Bower, Justin F. / Waterson, David / Faull, Alan / Poyser, Philip J. / Turner, Paul / McDermott, Benjamin / Campbell, Andrew D. / Hudson, Julian / James, Michael et al. | 2012
- 3900
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The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK)Davies, Christopher W. / Chaney, Joseph / Korbel, Gregory / Ringe, Dagmar / Petsko, Gregory A. / Ploegh, Hidde / Das, Chittaranjan et al. | 2012
- 3905
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Synthesis and anti-leishmanial activity of 1-aryl-β-carboline derivatives against Leishmania donovaniGohil, Vikrantsinh M. / Brahmbhatt, Keyur G. / Loiseau, Philippe M. / Bhutani, Kamlesh K. et al. | 2012
- 3905
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Synthesis and anti-leishmanial activity of 1-aryl-b-carboline derivatives against Leishmania donovaniGohil, V. M. / Brahmbhatt, K. G. / Loiseau, P. M. / Bhutani, K. K. et al. | 2012
- 3908
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Red fluorescent scaffold for highly sensitive protease activity probesKushida, Yu / Hanaoka, Kenjiro / Komatsu, Toru / Terai, Takuya / Ueno, Tasuku / Yoshida, Kengo / Uchiyama, Masanobu / Nagano, Tetsuo et al. | 2012
- 3912
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Synthesis of chalcone derivatives as potential anti-diabetic agentsHsieh, Chi-Ting / Hsieh, Tusty-Jiuan / El-Shazly, Mohamed / Chuang, Da-Wei / Tsai, Yi-Hong / Yen, Chiao-Ting / Wu, Shou-Fang / Wu, Yang-Chang / Chang, Fang-Rong et al. | 2012
- 3916
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Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonistsMittapalli, Gopi Kumar / Vellucci, Danielle / Yang, Jun / Toussaint, Marion / Brothers, Shaun P. / Wahlestedt, Claes / Roberts, Edward et al. | 2012
- 3921
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Development of a novel, CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) NAM probe (ML289) derived from a closely related mGlu5 PAMSheffler, Douglas J. / Wenthur, Cody J. / Bruner, Joshua A. / Carrington, Sheridan J.S. / Vinson, Paige N. / Gogi, Kiran K. / Blobaum, Anna L. / Morrison, Ryan D. / Vamos, Mitchell / Cosford, Nicholas D.P. et al. | 2012
- 3926
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Coumarin–trioxane hybrids: Synthesis and evaluation as a new class of antimalarial scaffoldsSashidhara, Koneni V. / Kumar, Abdhesh / Dodda, Ranga Prasad / Krishna, Naikade Niraj / Agarwal, Pooja / Srivastava, Kumkum / Puri, S.K. et al. | 2012
- 3931
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Targeting prostate cancer cells with a multivalent PSMA inhibitor-guided streptavidin conjugateLiu, Tiancheng / Nedrow-Byers, Jessie R. / Hopkins, Mark R. / Wu, Lisa Y. / Lee, Jeonghoon / Reilly, Peter T.A. / Berkman, Clifford E. et al. | 2012
- 3935
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The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1)Foot, Jonathan S. / Deodhar, Mandar / Turner, Craig I. / Yin, Ping / van Dam, Ellen M. / Silva, Diego G. / Olivieri, Aldo / Holt, Andrew / McDonald, Ian A. et al. | 2012
- 3941
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MK-8825: A potent and selective CGRP receptor antagonist with good oral activity in ratsBell, Ian M. / Stump, Craig A. / Gallicchio, Steven N. / Staas, Donnette D. / Zartman, C. Blair / Moore, Eric L. / Sain, Nova / Urban, Mark / Bruno, Joseph G. / Calamari, Amy et al. | 2012
- 3946
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Identification of a phenylacylsulfonamide series of dual Bcl-2/Bcl-xL antagonistsPerez, Heidi L. / Banfi, Patrizia / Bertrand, Jay / Cai, Zhen-Wei / Grebinski, James W. / Kim, Kyoung / Lippy, Jonathan / Modugno, Michele / Naglich, Joseph / Schmidt, Robert J. et al. | 2012
- 3951
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Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonistsSchroeder, Gretchen M. / Wei, Donna / Banfi, Patrizia / Cai, Zhen-Wei / Lippy, Jonathan / Menichincheri, Maria / Modugno, Michele / Naglich, Joseph / Penhallow, Becky / Perez, Heidi L. et al. | 2012
- 3957
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Investigation of the nucleotide triphosphate substrate specificity of Homo sapiens UDP-N-acetylgalactosamine pyrophosphorylase (AGX1)Xue, Mengyang / Guan, Wanyi / Zou, Yang / Fang, Junqiang / Liu, Xian-wei / Wang, Peng George / Wang, Fengshan et al. | 2012
- 3962
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E297G mutated bile salt export pump (BSEP) function enhancers derived from GW4064: Structural development study and separation from farnesoid X receptor-agonistic activityMisawa, Takashi / Hayashi, Hisamitsu / Makishima, Makoto / Sugiyama, Yuichi / Hashimoto, Yuichi et al. | 2012
- 3967
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Interactions of N-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-2-aryl-2-yl-acetamides and 1-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-phenyl}-3-aryl-2-yl-ureas with dopamine D2 and 5-hydroxytryptamine 5HT1A receptorsSukalovic, Vladimir / Ignjatovic, Djurdjica / Tovilovic, Gordana / Andric, Deana / Shakib, Kaveh / Kostic-Rajacic, Sladjana / Soskic, Vukic et al. | 2012
- 3973
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Identification of benzoxazole analogs as novel, S1P3 sparing S1P1 agonistsDeng, Guanghui / Meng, Qinghua / Liu, Qian / Xu, Xuesong / Xu, Qiongfeng / Ren, Feng / Guo, Taylor B. / Lu, Hongtao / Xiang, Jia-Ning / Elliott, John D. et al. | 2012
- 3978
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Towards a KCC2 blocker pharmacophore modelLebon, Florence / Pégurier, Cécile / Ledecq, Marie / Mathieu, Benoit / Bosman, Nathalie / Frycia, Anne / Lengelé, Sébastien / Dhurke, Kashinath / Kanduluru, Ananda Kumar / Meunier, Stéphane et al. | 2012
- 3983
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Identification of chalcones as potent and selective PDE5A1 inhibitorsNam, Ky-Youb / Choi, Nam Song / Han, Cheol Kyu / Ahn, Soon Kil et al. | 2012
- 3988
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Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activitySuchaud, Virginie / Bailly, Fabrice / Lion, Cédric / Tramontano, Enzo / Esposito, Francesca / Corona, Angela / Christ, Frauke / Debyser, Zeger / Cotelle, Philippe et al. | 2012
- 3993
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N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteasesSantana, Ana Bela / Lucas, Susana D. / Gonçalves, Lídia M. / Correia, Henrique F. / Cardote, Teresa A.F. / Guedes, Rita C. / Iley, Jim / Moreira, Rui et al. | 2012
- 3998
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Synthesis and evaluation of [18F]Fluorobutyl ethacrynic amide: A potential PET tracer for studying glutathione transferaseHuang, Ho-Lien / Yeh, Chun-Nan / Chang, Kang-Wei / Chen, Jenn-Tzong / Lin, Kun-Ju / Chiang, Li-Wu / Jeng, Kee-Ching / Wang, Wei-Ting / Lim, Ken-Hong / Chen, Caleb Gonshen et al. | 2012
- 4004
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Discovery of novel EGFR tyrosine kinase inhibitors by structure-based virtual screeningLi, Siyuan / Sun, Xianqiang / Zhao, Hongli / Tang, Yun / Lan, Minbo et al. | 2012
- 4010
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Anion-selective transport activities of tetrameric sterol–spermine conjugatesChen, Wen-Hua / Zhou, Jia / Wang, Yong-Min et al. | 2012
- 4014
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Synthesis of a ratiometric fluorescent peptide sensor for the highly selective detection of Cd2+Li, Yan / Li, Lianzhi / Pu, Xuewei / Ma, Guolin / Wang, Erqiong / Kong, Jinming / Liu, Zhipeng / Liu, Yangzhong et al. | 2012
- 4018
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Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agentsYen, Chiao-Ting / Nakagawa-Goto, Kyoko / Hwang, Tsong-Long / Morris-Natschke, Susan L. / Bastow, Kenneth F. / Wu, Yang-Chang / Lee, Kuo-Hsiung et al. | 2012
- 4023
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Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDK1 inhibitors discovered by fragment-based screeningLee, Angeline C.-H. / Ramanujulu, Pondy Murugappan / Poulsen, Anders / Williams, Meredith / Blanchard, Stéphanie / Ma, Diana M. / Bonday, Zahid / Goh, Kay Lin / Goh, Kee Chuan / Goh, Miah Kiat et al. | 2012
- 4028
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Acylprolinamides: A new class of peptide deformylase inhibitors with in vivo antibacterial activityAxten, Jeffrey M. / Medina, Jesús R. / Blackledge, Charles W. / Duquenne, Céline / Grant, Seth W. / Bobko, Mark A. / Peng, Tony / Miller, William H. / Pinckney, Theresa / Gallagher, Timothy F. et al. | 2012
- 4033
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Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitorsLe Brazidec, Jean-Yves / Pasis, Angela / Tam, Betty / Boykin, Christina / Wang, Deping / Marcotte, Douglas J. / Claassen, Gisela / Chong, Jer-Hong / Chao, Jianhua / Fan, Junhua et al. | 2012
- 4038
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5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMPChen, Haijun / Tsalkova, Tamara / Mei, Fang C. / Hu, Yaohua / Cheng, Xiaodong / Zhou, Jia et al. | 2012
- 4044
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Synthesis and structure–activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitorsLee, Jongkook / Han, Sun-Young / Jung, Heejung / Yang, Jeon / Choi, Jie-Won / Chae, Chong Hack / Park, Chi Hoon / Choi, Sang Un / Lee, Kwangho / Ha, Jae Du et al. | 2012
- 4049
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Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13Yu, Mi-Sun / Lee, June / Lee, Jin Moo / Kim, Younggyu / Chin, Young-Won / Jee, Jun-Goo / Keum, Young-Sam / Jeong, Yong-Joo et al. | 2012
- 4055
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The antibacterial activity of 4,4′-bipyridinium amphiphiles with conventional, bicephalic and gemini architecturesGrenier, Melissa C. / Davis, Robert W. / Wilson-Henjum, Kelsey L. / LaDow, Jade E. / Black, Jacob W. / Caran, Kevin L. / Seifert, Kyle / Minbiole, Kevin P.C. et al. | 2012
- 4055
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The antibacterial activity of 4,4prime-bipyridinium amphiphiles with conventional, bicephalic and gemini architecturesGrenier, M. C. / Davis, R. W. / Wilson-Henjum, K. L. / LaDow, J. E. / Black, J. W. / Caran, K. L. / Seifert, K. / Minbiole, K. P. et al. | 2012
- 4059
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7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligandsBanister, Samuel D. / Rendina, Louis M. / Kassiou, Michael et al. | 2012
- 4064
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Pre-steady state kinetic analysis of cyclobutyl derivatives of 2prime-deoxyadenosine 5prime-triphosphate as inhibitors of HIV-1 reverse transcriptaseKim, J. / Wang, L. / Li, Y. / Becnel, K. D. / Frey, K. M. / Garforth, S. J. / Prasad, V. R. / Schinazi, R. F. / Liotta, D. C. / Anderson, K. S. et al. | 2012
- 4064
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Pre-steady state kinetic analysis of cyclobutyl derivatives of 2′-deoxyadenosine 5′-triphosphate as inhibitors of HIV-1 reverse transcriptaseKim, Jiae / Wang, Ligong / Li, Yongfeng / Becnel, Kimberlynne D. / Frey, Kathleen M. / Garforth, Scott J. / Prasad, Vinayaka R. / Schinazi, Raymond F. / Liotta, Dennis C. / Anderson, Karen S. et al. | 2012
- 4068
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Chromatin structure determines accessibility of a hairpin polyamide–chlorambucil conjugate at histone H4 genes in pancreatic cancer cellsJespersen, Christine / Soragni, Elisabetta / James Chou, C. / Arora, Paramjit S. / Dervan, Peter B. / Gottesfeld, Joel M. et al. | 2012
- 4072
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Anticonvulsant activity of artificial sweeteners: A structural link between sweet-taste receptor T1R3 and brain glutamate receptorsTalevi, Alan / Enrique, Andrea V. / Bruno-Blanch, Luis E. et al. | 2012
- 4075
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An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidinesParmar, Narsidas J. / Pansuriya, Bhavesh R. / Barad, Hitesh A. / Kant, Rajni / Gupta, Vivek K. et al. | 2012
- 4080
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A novel series of pyrazolylpiperidine N-type calcium channel blockersSubasinghe, Nalin L. / Wall, Mark J. / Winters, Michael P. / Qin, Ning / Lubin, Mary Lou / Finley, Michael F.A. / Brandt, Michael R. / Neeper, Michael P. / Schneider, Craig R. / Colburn, Raymond W. et al. | 2012
- 4084
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Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activityKeck, Gary E. / Poudel, Yam B. / Rudra, Arnab / Stephens, Jeffrey C. / Kedei, Noemi / Lewin, Nancy E. / Blumberg, Peter M. et al. | 2012
- 4089
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Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitorsBode, Christiane M. / Boezio, Alessandro A. / Albrecht, Brian K. / Bellon, Steven F. / Berry, Loren / Broome, Martin A. / Choquette, Deborah / Dussault, Isabelle / Lewis, Richard T. / Lin, Min-Hwa Jasmine et al. | 2012
- 4094
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Ethyl 2,4,6-trihydroxybenzoate is an agonistic ligand for liver X receptor that induces cholesterol efflux from macrophages without affecting lipid accumulation in HepG2 cellsHoang, Minh-Hien / Jia, Yaoyao / Jun, Hee-jin / Lee, Ji-Hae / Lee, Dong-Ho / Hwang, Bang-Yeon / Kim, Woo-Jin / Lee, Hak-Ju / Lee, Sung-Joon et al. | 2012
- 4100
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Synthesis, characterization and in vitro anti-tumor activities of matrine derivativesWang, Lisheng / You, Yejun / Wang, Songqing / Liu, Xu / Liu, Buming / Wang, Jinni / Lin, Xiao / Chen, Mingsheng / Liang, Gang / Yang, Hua et al. | 2012
- 4103
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Enhancement of fluorescence quenching and exciplex formation in DNA major groove by double incorporation of modified fluorescent deoxyuridinesTanaka, Makiko / Oguma, Kazuhiro / Saito, Yoshio / Saito, Isao et al. | 2012
- 4106
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Fluorescent 2-styrylpyridazin-3(2H)-one derivatives as probes targeting amyloid-beta plaques in Alzheimer’s diseasePark, Yong Dae / Park, Jeong Hoon / Hur, Min Goo / Kim, Sang Wook / Min, Jung-Joon / Park, Seung-Hwan / Yoo, Yung Joon / Yoon, Yong-Jin / Yang, Seung Dae et al. | 2012
- 4111
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Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 1Delouvrié, Bénédicte / Al-Kadhimi, Katherine / Arnould, Jean-Claude / Barry, Simon T. / Cross, Darren A.E. / Didelot, Myriam / Gavine, Paul R. / Germain, Hervé / Harris, Craig S. / Hughes, Adina M. et al. | 2012
- 4111
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Structure-activity relationship of a series of non peptidic RGD integrin antagonists targeting a5b1: Part 1Delouvrie, B. / Al-Kadhimi, K. / Arnould, J. C. / Barry, S. T. / Cross, D. A. / Didelot, M. / Gavine, P. R. / Germain, H. / Harris, C. S. / Hughes, A. M. et al. | 2012
- 4117
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Structure-activity relationship of a series of non peptidic RGD integrin antagonists targeting a5b1: Part 2Delouvrie, B. / Al-Kadhimi, K. / Arnould, J. C. / Barry, S. T. / Cross, D. A. / Didelot, M. / Gavine, P. R. / Germain, H. / Harris, C. S. / Hughes, A. M. et al. | 2012
- 4117
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Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 2Delouvrié, Bénédicte / Al-Kadhimi, Katherine / Arnould, Jean-Claude / Barry, Simon T. / Cross, Darren A.E. / Didelot, Myriam / Gavine, Paul R. / Germain, Hervé / Harris, Craig S. / Hughes, Adina M. et al. | 2012
- 4122
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Total synthesis and dual PPARα/γ agonist effects of Amorphastilbol and its synthetic derivativesKim, Taejung / Lee, Woojung / Jeong, Kyu Hyuk / Song, Jung Ho / Park, Soon-Hye / Choi, Pilju / Kim, Su-Nam / Lee, Seokjoon / Ham, Jungyeob et al. | 2012
- 4122
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Total synthesis and dual PPARa/g agonist effects of Amorphastilbol and its synthetic derivativesKim, T. / Lee, W. / Jeong, K. H. / Song, J. H. / Park, S. H. / Choi, P. / Kim, S. N. / Lee, S. / Ham, J. et al. | 2012
- 4127
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Synthesis and characterization of 2′-C-Me branched C-nucleosides as HCV polymerase inhibitorsCho, Aesop / Zhang, Lijun / Xu, Jie / Babusis, Darius / Butler, Thomas / Lee, Rick / Saunders, Oliver L. / Wang, Ting / Parrish, Jay / Perry, Jason et al. | 2012
- 4127
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Synthesis and characterization of 2prime-C-Me branched C-nucleosides as HCV polymerase inhibitorsCho, A. / Zhang, L. / Xu, J. / Babusis, D. / Butler, T. / Lee, R. / Saunders, O. L. / Wang, T. / Parrish, J. / Perry, J. et al. | 2012
- 4133
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Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitorsChu, Lin / Armstrong, Helen M. / Chang, Linda L. / Cheng, Amy F. / Colwell, Lawrence / Cui, Jisong / Evans, Jilly / Galka, Amy / Goulet, Mark T. / Hayes, Nancy et al. | 2012
- 4139
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Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based designAkula, Nagaraju / Midzak, Andrew / Lecanu, Laurent / Papadopoulos, Vassilios et al. | 2012
- 4144
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Synthesis of PECAM-1-specific 64Cu PET imaging agent: Evaluation of myocardial infarction caused by ischemia-reperfusion injury in mouseXiao, Li / Zhang, Yi / Yang, Zequan / Xu, Yaqin / Kundu, Bijoy / Chordia, Mahendra D. / Pan, Dongfeng et al. | 2012
- 4148
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Thieno[3,2-b]thiophene-2-carboxylic acid derivatives as GPR35 agonistsDeng, Huayun / Hu, Jieyu / Hu, Haibei / He, Mingqian / Fang, Ye et al. | 2012
- 4153
-
Structure–activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitorsPajouhesh, Hassan / Feng, Zhong-Ping / Zhang, Lingyun / Pajouhesh, Hossein / Jiang, Xinpo / Hendricson, Adam / Dong, Haiheng / Tringham, Elizabeth / Ding, Yanbing / Vanderah, Todd W. et al. | 2012
- 4159
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Depigmenting activities of kojic acid derivatives without tyrosinase inhibitory activitiesCho, Jun-Cheol / Rho, Ho Sik / Joo, Yung Hyup / Lee, Chang Seok / Lee, Jaekyoung / Ahn, Soo Mi / Kim, Jung Eun / Shin, Song Seok / Park, Young-Ho / Suh, Kyung-Do et al. | 2012
- 4163
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Sulfonyl-morpholino-pyrimidines: SAR and development of a novel class of selective mTOR kinase inhibitorFinlay, M. Raymond V. / Buttar, David / Critchlow, Susan E. / Dishington, Allan P. / Fillery, Shaun M. / Fisher, Eric / Glossop, Steve C. / Graham, Mark A. / Johnson, Trevor / Lamont, Gillian M. et al. | 2012
- 4169
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Pharmacophore-based small molecule CXCR4 ligandsNarumi, Tetsuo / Tanaka, Tomohiro / Hashimoto, Chie / Nomura, Wataru / Aikawa, Haruo / Sohma, Akira / Itotani, Kyoko / Kawamata, Miyako / Murakami, Tsutomu / Yamamoto, Naoki et al. | 2012
- 4173
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Kappa agonist CovX-BodiesRoberts, Lee R. / Brady, Kevin / Brown, Amy / Davey, Doreen / Feng, Lijin / Huang, Hanhua / Liu, Dingguo / Malet, Laia / McMurray, Gordon / Phelan, Anne et al. | 2012
- 4179
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Identification of blapsins A and B as potent small-molecule 14-3-3 inhibitors from the insect Blaps japanensisYan, Yong-Ming / Dai, Huan-Qin / Du, Yuhong / Schneider, Bernd / Guo, Hui / Li, Dian-Peng / Zhang, Li-Xin / Fu, Haian / Dong, Xiao-Ping / Cheng, Yong-Xian et al. | 2012
- 4182
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Stereoselective synthesis of alpinoid-C and its analogues and study of their cytotoxic activity against cancer cell linesPurushotham Reddy, S. / Chinnababu, B. / Shekhar, V. / Kumar Reddy, D. / Bhanuprakash, G.V.S. / Velatoor, L.R. / Venkateswara Rao, J. / Venkateswarlu, Y. et al. | 2012
- 4185
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Discovery of potent antimicrobial peptide analogs of Ixosin-BLung, Feng-Di T. / Wang, Kai-Shiuan / Liao, Zih-Jie / Hsu, Sheng-Kai / Song, Fei-Yi / Liou, Chien-Chung / Wu, Yu-Shan et al. | 2012
- 4189
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Structure and property based design, synthesis and biological evaluation of g-lactam based HDAC inhibitors: Part IILee, C. / Choi, E. / Cho, M. / Lee, B. / Oh, S. J. / Park, S. K. / Lee, K. / Kim, H. M. / Han, G. et al. | 2012
- 4189
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Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors: Part IILee, Chulho / Choi, Eunhyun / Cho, Misun / Lee, Boah / Oh, Soo Jin / Park, Song-Kyu / Lee, Kiho / Kim, Hwan Mook / Han, Gyoonhee et al. | 2012
- 4193
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Simple, fast and efficient synthesis of b-keto esters from the esters of heteroaryl compounds, its antimicrobial study and cytotoxicity towards various cancer cell linesVenkat Ragavan, R. / Vijayakumar, V. / Rajesh, K. / Palakshi Reddy, B. / Karthikeyan, S. / Suchetha Kumari, N. et al. | 2012
- 4193
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Simple, fast and efficient synthesis of β-keto esters from the esters of heteroaryl compounds, its antimicrobial study and cytotoxicity towards various cancer cell linesVenkat Ragavan, R. / Vijayakumar, V. / Rajesh, K. / Palakshi Reddy, B. / Karthikeyan, S. / Suchetha Kumari, N. et al. | 2012
- 4198
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Synthesis of constrained benzocinnolinone analogues of CEP-26401 (irdabisant) as potent, selective histamine H3 receptor inverse agonistsJosef, Kurt A. / Aimone, Lisa D. / Lyons, Jacquelyn / Raddatz, Rita / Hudkins, Robert L. et al. | 2012
- 4203
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S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: Potent inhibitory activity of 9-(2-deoxy-2-fluoro-b,d-arabinofuranosyl)adenineShokar, A. / Au, A. / An, S. H. / Tong, E. / Garza, G. / Zayas, J. / Wnuk, S. F. / Land, K. M. et al. | 2012
- 4203
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S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: Potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,d-arabinofuranosyl)adenineShokar, Ajit / Au, Aaron / An, Seung Hwan / Tong, Elsie / Garza, Gabriel / Zayas, Jessica / Wnuk, Stanislaw F. / Land, Kirkwood M. et al. | 2012
- IFC
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Editorial board| 2012